Understanding the relation between socioeconomic position and inflammation in post-menopausal women: education, income and occupational prestige
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Understanding the relation between socioeconomic position and inflammation in post-menopausal women : education, income and occupational prestige. / Pedersen, Jolene Masters; Budtz-Jørgensen, Esben; De Roos, Anneclaire; Garcia, Lorena; Lund, Rikke; Rod, Naja Hulvej; Kroenke, Candyce; Chan, Kei Hang Katie; Liu, Simin; Michael, Yvonne.
In: European Journal of Public Health, Vol. 27, No. 6, 01.12.2017, p. 1074-1079.Research output: Contribution to journal › Journal article › Research › peer-review
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TY - JOUR
T1 - Understanding the relation between socioeconomic position and inflammation in post-menopausal women
T2 - education, income and occupational prestige
AU - Pedersen, Jolene Masters
AU - Budtz-Jørgensen, Esben
AU - De Roos, Anneclaire
AU - Garcia, Lorena
AU - Lund, Rikke
AU - Rod, Naja Hulvej
AU - Kroenke, Candyce
AU - Chan, Kei Hang Katie
AU - Liu, Simin
AU - Michael, Yvonne
PY - 2017/12/1
Y1 - 2017/12/1
N2 - Background: The role of occupational prestige, a direct measure of the perceived status of job and job holder, in inflammation is unknown. To contribute to understanding the pathways by which socioeconomic position (SEP) is associated with inflammation, we aimed to estimate the direct effects of education, income and occupational prestige on C-reactive protein (CRP) and to describe the relationship between these markers and CRP.Methods: The study was based on 2026 post-menopausal women enrolled in the Women’s Health Initiative-Observational Study. Occupational prestige was determined by linking a text description of longest held occupation with a social status item from the Occupational Information Network. Path analysis was employed to estimate direct and mediated effects.Results: The study suggests that higher levels of education, income, and occupational prestige are associated with 8% (95% CI as percentage change −12, −4), 5% [95% CI (−8, −2) and 4% (95% CI − 7, −1)] lower levels of CRP, respectively. The inverse association between education and CRP was explained by the effect of education on income and occupational prestige. The effect of occupational prestige on CRP was independent of mediators in the model.Conclusions: The findings indicate that education may work to influence CRP primarily through increasing income and occupational prestige and provides evidence that occupational prestige captures a unique aspect of SEP.
AB - Background: The role of occupational prestige, a direct measure of the perceived status of job and job holder, in inflammation is unknown. To contribute to understanding the pathways by which socioeconomic position (SEP) is associated with inflammation, we aimed to estimate the direct effects of education, income and occupational prestige on C-reactive protein (CRP) and to describe the relationship between these markers and CRP.Methods: The study was based on 2026 post-menopausal women enrolled in the Women’s Health Initiative-Observational Study. Occupational prestige was determined by linking a text description of longest held occupation with a social status item from the Occupational Information Network. Path analysis was employed to estimate direct and mediated effects.Results: The study suggests that higher levels of education, income, and occupational prestige are associated with 8% (95% CI as percentage change −12, −4), 5% [95% CI (−8, −2) and 4% (95% CI − 7, −1)] lower levels of CRP, respectively. The inverse association between education and CRP was explained by the effect of education on income and occupational prestige. The effect of occupational prestige on CRP was independent of mediators in the model.Conclusions: The findings indicate that education may work to influence CRP primarily through increasing income and occupational prestige and provides evidence that occupational prestige captures a unique aspect of SEP.
U2 - 10.1093/eurpub/ckx070
DO - 10.1093/eurpub/ckx070
M3 - Journal article
C2 - 29186460
VL - 27
SP - 1074
EP - 1079
JO - European Journal of Public Health
JF - European Journal of Public Health
SN - 1101-1262
IS - 6
ER -
ID: 188196772