Ian David Hickson

Ian David Hickson

Professor


  1. Published

    The Escherichia coli Tus-Ter replication fork barrier causes site-specific DNA replication perturbation in yeast

    Larsen, N. B., Sass, E., Suski, C., Mankouri, H. W. & Hickson, Ian David, 2014, In: Nature Communications. 5, p. 1-10 10 p., 3574.

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    Tus-Ter as a tool to study site-specific DNA replication perturbation in eukaryotes

    Larsen, N. B., Hickson, Ian David & Mankouri, H. W., 1 Oct 2014, In: Cell Cycle. 13, 19, p. 2994-8 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    A Molecular Toolbox to Engineer Site-Specific DNA Replication Perturbation

    Larsen, N. B., Hickson, Ian David & Mankouri, H. W., 2018, Genome Instability: Methods and Protocols. Springer, Vol. 1672. p. 295-309 15 p. (Methods in molecular biology (Clifton, N.J.)).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  4. Published

    Stalled replication forks generate a distinct mutational signature in yeast

    Larsen, N. B., Liberti, S. E., Vogel, Ivan, Jorgensen, S. W., Hickson, Ian David & Mankouri, H. W., 2017, In: Proceedings of the National Academy of Sciences of the United States of America. 114, 36, p. 9665-9670

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    RecQ Helicases: Conserved Guardians of Genomic Integrity

    Larsen, N. B. & Hickson, Ian David, 2013, In: Advances in Experimental Medicine and Biology. 767, p. 161-84 24 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    The origins and processing of ultra fine anaphase DNA bridges

    Liu, Ying, Nielsen, Christian Friberg, Yao, Q. & Hickson, Ian David, 30 Apr 2014, In: Current Opinion in Genetics & Development. 26C, p. 1-5 5 p.

    Research output: Contribution to journalReviewResearchpeer-review

  7. Published

    53BP1 nuclear bodies form around DNA lesions generated by mitotic transmission of chromosomes under replication stress

    Lukas, Claudia, Savic, V., Bekker-Jensen, Simon Holst, Doil, C., Neumann, B., Pedersen, R. S., Grøfte, M., Chan, K. L., Hickson, Ian David, Bartek, J. & Lukas, Jiri, 1 Mar 2011, In: Nature Cell Biology. 13, 3, p. 243-53 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    High-resolution mapping of mitotic DNA synthesis regions and common fragile sites in the human genome through direct sequencing

    Macheret, M., Bhowmick, Rahul, Sobkowiak, K., Padayachy, L., Mailler, J., Hickson, Ian David & Halazonetis, T. D., 2020, In: Cell Research. 30, p. 997–1008

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    How unfinished business from S-phase affects mitosis and beyond

    Mankouri, H. W., Huttner, D. & Hickson, Ian David, 16 Oct 2013, In: EMBO Journal. 32, 20, p. 2661-71 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    A novel antirecombinase gains PARIty

    Mankouri, H. W., Chu, W. K. & Hickson, Ian David, Jan 2012, In: Molecular Cell. 45, 1, p. 6-7 2 p.

    Research output: Contribution to journalReviewResearchpeer-review

  11. Published

    The RecQ helicase-topoisomerase III-Rmi1 complex: a DNA structure-specific 'dissolvasome'?

    Mankouri, H. W. & Hickson, Ian David, 1 Dec 2007, In: Trends in Biochemical Sciences. 32, 12, p. 538-46 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Shu proteins promote the formation of homologous recombination intermediates that are processed by Sgs1-Rmi1-Top3

    Mankouri, H. W., Ngo, H. & Hickson, Ian David, 1 Oct 2007, In: Molecular Biology of the Cell. 18, 10, p. 4062-73 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Holliday junction-containing DNA structures persist in cells lacking Sgs1 or Top3 following exposure to DNA damage

    Mankouri, H. W., Ashton, T. M. & Hickson, Ian David, 22 Mar 2011, In: Proceedings of the National Academy of Sciences USA (PNAS). 108, 12, p. 4944-9 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Esc2 and Sgs1 act in functionally distinct branches of the homologous recombination repair pathway in Saccharomyces cerevisiae

    Mankouri, H. W., Ngo, H. & Hickson, Ian David, 1 Mar 2009, In: Molecular Biology of the Cell. 20, 6, p. 1683-94 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Top3 processes recombination intermediates and modulates checkpoint activity after DNA damage

    Mankouri, H. W. & Hickson, Ian David, 1 Oct 2006, In: Molecular Biology of the Cell. 17, 10, p. 4473-83 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Mutations in TOP3A Cause a Bloom Syndrome-like Disorder

    GOSgene, G., 2018, In: American Journal of Human Genetics. 103, 2, p. 221-231 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Nonlinear mechanics of human mitotic chromosomes

    Meijering, A. E. C., Sarlós, K., Nielsen, Christian Friberg, Witt, H., Harju, J., Kerklingh, E., Haasnoot, G. H., Bizard, A. H., Heller, I., Broedersz, C. P., Liu, Ying, Peterman, E. J. G., Hickson, Ian David & Wuite, G. J. L., 2022, In: Nature. p. 545–550

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Replication stress activates DNA repair synthesis in mitosis

    Minocherhomji, S., Ying, S., Bjerregaard, Victoria Alexandra, Bursomanno, S., Aleliunaite, A., Wu, Wei, Mankouri, H. W., Shen, H., Liu, Ying & Hickson, Ian David, 10 Dec 2015, In: Nature. 528, 7581, p. 286-90 5 p.

    Research output: Contribution to journalLetterResearchpeer-review

  19. Published

    Structure-specific endonucleases: guardians of fragile site stability

    Minocherhomji, S. & Hickson, Ian David, May 2014, In: Trends in Cell Biology. 24, 5, p. 321-327 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Development and evaluation of human AP endonuclease inhibitors in melanoma and glioma cell lines

    Mohammed, M. Z., Vyjayanti, V. N., Laughton, C. A., Dekker, L. V., Fischer, P. M., Wilson, D. M., Abbotts, R., Shah, S., Patel, P. M., Hickson, Ian David & Madhusudan, S., 15 Feb 2011, In: British Journal of Cancer Management. 104, 4, p. 653-63 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Cyclin E overexpression in the Drosophila accessory gland induces tissue dysplasia

    Molano-Fernández, M., Hickson, Ian David & Herranz, Hector, 2023, In: Frontiers in Cell and Developmental Biology. 10, 992253.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Developing T lymphocytes are uniquely sensitive to a lack of topoisomerase III alpha

    Mönnich, M., Hess, I., Wiest, W., Bachrati, C., Hickson, Ian David, Schorpp, M. & Boehm, T., Sep 2010, In: European Journal of Immunology. 40, 9, p. 2379-84 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Acute inactivation of the replicative helicase in human cells triggers MCM8-9-dependent DNA synthesis

    Natsume, T., Nishimura, K., Minocherhomji, S., Bhowmick, Rahul, Hickson, Ian David & Kanemaki, M. T., 2017, In: Genes & Development. 31, 8, p. 816-829 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Crystal structure of the Bloom's syndrome helicase indicates a role for the HRDC domain in conformational changes

    Newman, J. A., Savitsky, P., Allerston, C. K., Bizard, A. H., Özer, Ö., Sarlós, K., Liu, Ying, Pardon, E., Steyaert, J., Hickson, Ian David & Gileadi, O., 2015, In: Nucleic Acids Research. 43, 10, p. 5221-35 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Regulation of gene expression by the BLM helicase correlates with the presence of G-quadruplex DNA motifs

    Nguyen, G. H., Tang, W., Robles, A. I., Beyer, R. P., Gray, L. T., Welsh, J. A., Schetter, A. J., Kumamoto, K., Wang, X. W., Hickson, Ian David, Maizels, N., Monnat, R. J. & Harris, C. C., 8 Jul 2014, In: Proceedings of the National Academy of Sciences of the United States of America. 111, 27, p. 9905-10 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

ID: 17446319