Lene Juel Rasmussen
Professor
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14-3-3 checkpoint regulatory proteins interact specifically with DNA repair protein human exonuclease 1 (hEXO1) via a semi-conserved motif
Andersen, S. D., Keijzers, G., Rampakakis, E., Engels, K., Luhn, P., El-Shemerly, M., Nielsen, Finn Cilius, Du, Y., May, A., Bohr, Vilhelm, Ferrari, S., Zannis-Hadjopoulos, M., Fu, H. & Rasmussen, Lene Juel, Mar 2012, In: D N A Repair. 11, 3, p. 267-77 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Helicobacter pylori infection affects mitochondrial function and DNA repair, thus, mediating genetic instability in gastric cells
Machado, A. M. D., Desler, C., Boggild, S., Strickertsson, J. A. B., Friis-Hansen, Lennart Jan, Figueiredo, C., Seruca, R. & Rasmussen, Lene Juel, 2013, In: Mechanisms of Ageing and Development. 134, 10, p. 460-466 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Rev1 deficiency induces a metabolic shift in MEFs that can be manipulated by the NAD+ precursor nicotinamide riboside
Anugula, Sharath, Li, Zhiquan, Li, Yuan, Hendriksen, A., Christensen, P. B., Wang, L., Monk, J. M., de Wind, N., Bohr, Vilhelm, Desler, Claus, Naviaux, R. K. & Rasmussen, Lene Juel, 2023, In: Heliyon. 9, 6, e17392.Research output: Contribution to journal › Journal article › Research › peer-review
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A Ketogenic Diet Improves Mitochondrial Biogenesis and Bioenergetics via the PGC1α-SIRT3-UCP2 Axis
Hasan-Olive, M. M., Lauritzen, K. H., Ali, M., Rasmussen, Lene Juel, Storm-Mathisen, J. & Bergersen, L. H., 2019, In: Neurochemical Research. 44, 1, p. 22-37 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
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A Novel Rrm3 Function in Restricting DNA Replication via an Orc5-Binding Domain Is Genetically Separable from Rrm3 Function as an ATPase/Helicase in Facilitating Fork Progression
Syed, S., Desler, Claus, Rasmussen, Lene Juel & Schmidt, K. H., Dec 2016, In: P L o S Genetics. 12, 12, 28 p., e1006451.Research output: Contribution to journal › Journal article › Research › peer-review
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A functional assay–based procedure to classify mismatch repair gene variants in Lynch syndrome
Drost, M., Tiersma, Y., Thompson, B. A., Frederiksen, J. H., Keijzers, G., Glubb, D., Kathe, S., Osinga, J., Westers, H., Pappas, L., Boucher, K. M., Molenkamp, S., Zonneveld, J. B., van Asperen, C. J., Goldgar, D. E., Wallace, S. S., Sijmons, R. H., Spurdle, A. B., Rasmussen, L. J., Greenblatt, M. S. & 2 others, , 2019, In: Genetics in Medicine. 21, p. 1486–1496Research output: Contribution to journal › Journal article › Research › peer-review
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A rapid and cell-free assay to test the activity of lynch syndrome-associated MSH2 and MSH6 missense variants
Drost, M., Zonneveld, J. B. M., van Hees, S., Rasmussen, Lene Juel, Hofstra, R. M. W. & de Wind, N., 2012, In: Human Mutation. 33, 3, p. 488-94 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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ARDD 2020: from aging mechanisms to interventions
Mkrtchyan, G. V., Abdelmohsen, K., Andreux, P., Bagdonaite, I., Barzilai, N., Brunak, S., Cabreiro, F., Cabo, R. D., Campisi, J., Cuervo, A. M., Demaria, M., Ewald, C. Y., Fang, E. F., Faragher, R., Ferrucci, L., Freund, A., Silva-García, C. G., Georgievskaya, A., Gladyshev, V. N., Glass, D. J. & 46 others, , 2020, In: Aging. 12, 24, p. 24486-24503 18 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Acquired Localized Cutis Laxa due to Increased Elastin Turnover
Nygaard, R. H., Maynard, S., Schjerling, P., Kjær, M., Qvortrup, Klaus, Bohr, Vilhelm, Rasmussen, Lene Juel, Jemec, Gregor & Heidenheim, M., 14 Jun 2016, In: Case Reports in Dermatology. 8, 1, p. 42-51 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Aging, longevity and health
Rasmussen, Lene Juel, Sander, M., Wewer, Ulla M. & Bohr, Vilhelm, 23 Jul 2011, In: Mechanisms of Ageing and Development. p. 522-32 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Alterations of monocarboxylate transporter densities during hypoxia in brain and breast tumour cells
Cheng, C., Edin, N. F. J., Lauritzen, K. H., Aspmodal, I., Christoffersen, S., Jian, L., Rasmussen, Lene Juel, Pettersen, E. O., Xiaoqun, G. & Bergersen, L. H., Jun 2012, In: Cellular oncology (Dordrecht). 35, 3, p. 217-27 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Analysis of the antimicrobial susceptibility of the ionizing radiation-resistant bacterium Deinococcus radiodurans: implications for bioremediation of radioactive waste
Bouchami, O., Sghaier, H., Desler, Claus, Lazim, H., Saidi, M., Rasmussen, Lene Juel & Ben Hassan, A., 2011, In: Annals of Microbiology.Research output: Contribution to journal › Journal article › Research › peer-review
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Application of a 5-tiered scheme for standardized classification of 2,360 unique mismatch repair gene variants in the InSiGHT locus-specific database
Thompson, B. A., Spurdle, A. B., Plazzer, J-P., Greenblatt, M. S., Akagi, K., Al-Mulla, F., Bapat, B., Bernstein, I., Capellá, G., den Dunnen, J. T., du Sart, D., Fabre, A., Farrell, M. P., Farrington, S. M., Frayling, I. M., Frebourg, T., Goldgar, D. E., Heinen, C. D., Holinski-Feder, E., Kohonen-Corish, M. & 31 others, , Feb 2014, In: Nature Genetics. 46, 2, p. 107-115 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Approaches to diagnose DNA mismatch repair gene defects in cancer
Peña-Diaz, J. & Rasmussen, Lene Juel, Feb 2016, In: DNA Repair. 38, p. 147-154 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Assessing Genetic Variants of Uncertain Significance: The Example of Lynch Syndrome
Rasmussen, Lene Juel & Heinen, C. D., 15 Apr 2014Research output: Other contribution › Net publication - Internet publication › Communication
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Associations of subjective vitality with DNA damage, cardiovascular risk factors and physical performance
Maynard, S., Keijzers, G., Hansen, Åse Marie, Osler, Merete, Molbo, Drude, Bendix, L., Møller, Peter, Loft, Steffen, Moreno-Villanueva, M., Bürkle, A., Hvitby, C. P., Schurman, S. H., Stevnsner, T. V., Rasmussen, Lene Juel, Avlund, K. & Bohr, Vilhelm, Jan 2015, In: Acta Physiologica (Print). 213, 1, p. 156-170 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Bacterial infection increases risk of carcinogenesis by targeting mitochondria
Strickertsson, J. A. B., Desler, Claus & Rasmussen, Lene Juel, Dec 2017, In: Seminars in Cancer Biology. 47, p. 95-100 6 p.Research output: Contribution to journal › Review › Research › peer-review
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Bi-directional routing of DNA mismatch repair protein human exonuclease 1 to replication foci and DNA double strand breaks
Liberti, S. E., Andersen, S. D., Wang, J., May, A., Miron, S., Perderiset, M., Keijzers, G., Nielsen, Finn Cilius, Charbonnier, J., Bohr, Vilhelm & Rasmussen, Lene Juel, 2 Jan 2011, In: DNA Repair. 10, 1, p. 73-86 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Biochemical characterization of MLH3 missense mutations does not reveal an apparent role of MLH3 in Lynch syndrome
Ou, J., Rasmussen, M., Westers, H., Andersen, S. D., Jager, P. O., Kooi, K. A., Niessen, R. C., Eggen, B. J. L., Nielsen, Finn Cilius, Kleibeuker, J. H., Sijmons, R. H., Rasmussen, Lene Juel & Hofstra, R. M. W., 2009, In: Genes, Chromosomes & Cancer. 48, 4, p. 340-50 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Bioenergetic Changes during Differentiation of Human Embryonic Stem Cells along the Hepatic Lineage
Hopkinson, B. M., Desler, Claus, Kalisz, M., Vestentoft, P. S., Rasmussen, Lene Juel & Bisgaard, Hanne Cathrine, 2017, In: Oxidative Medicine and Cellular Longevity. 2017, 11 p., 5080128.Research output: Contribution to journal › Journal article › Research › peer-review
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Bloom syndrome DNA helicase deficiency is associated with oxidative stress and mitochondrial network changes
Subramanian, V., Rodemoyer, B., Shastri, V., Rasmussen, Lene Juel, Desler, Claus & Schmidt, K. H., 2021, In: Scientific Reports. 11, 2157.Research output: Contribution to journal › Journal article › Research › peer-review
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CNOT6: A Novel Regulator of DNA Mismatch Repair
Song, P., Liu, S., Liu, D., Keijzers, G., Bakula, Daniela Janina, Duan, S., de Wind, N., Ye, Z., Vakhrushev, Sergey, Scheibye-Knudsen, Morten & Rasmussen, Lene Juel, 2022, In: Cells. 11, 3, 521.Research output: Contribution to journal › Journal article › Research › peer-review
Cadmium inhibits human DNA mismatch repair in vivo
Lützen, A., Liberti, S. E. & Rasmussen, Lene Juel, 13 Aug 2004, In: Biochemical and Biophysical Research Communications. 321, 1, p. 21-5 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Caregiver Engagement in Stroke Care: Opportunities and Challenges in Australia and Denmark
Lobo, E. H. S., Abdelrazek, M., Grundy, J., Kensing, F., Livingston, P. M., Rasmussen, Lene Juel, Islam, S. M. S. & Frølich, Anne, 2021, In: Frontiers in Public Health. 9, 6 p., 758808.Research output: Contribution to journal › Journal article › Research › peer-review
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Characterization of a highly conserved binding site of Mlh1 required for exonuclease I-dependent mismatch repair
Dherin, C., Gueneau, E., Francin, M., Nunez, M., Miron, S., Liberti, S. E., Rasmussen, Lene Juel, Zinn-Justin, S., Gilquin, B., Charbonnier, J. & Boiteux, S., 2009, In: Molecular and Cellular Biology. 29, 3, p. 907-18 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 13558388
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Is There a Link between Mitochondrial Reserve Respiratory Capacity and Aging?
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Enterococcus faecalis infection causes inflammation, intracellular oxphos-independent ROS production, and DNA damage in human gastric cancer cells
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LIFESTAT – Living with statins: An interdisciplinary project on the use of statins as a cholesterol-lowering treatment and for cardiovascular risk reduction
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