Ian David Hickson

Ian David Hickson

Professor


  1. 2016
  2. Published

    PICH promotes mitotic chromosome segregation: Identification of a novel role in rDNA disjunction

    Nielsen, Christian Friberg & Hickson, Ian David, 17 Oct 2016, In: Cell Cycle. 15, 20, p. 2704-2711 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Rad54 and Mus81 cooperation promotes DNA damage repair and restrains chromosome missegregation

    Ghamrasni, S. E., Cardoso, R., Li, L., Guturi, K. K. N., Bjerregaard, Victoria Alexandra, Liu, Ying, Venkatesan, S., Hande, M. P., Henderson, J. T., Sanchez, O., Hickson, Ian David, Hakem, A. & Hakem, R., 15 Sep 2016, In: Oncogene. 35, 37, p. 4836-4845 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Characterization of the NTPR and BD1 interacting domains of the human PICH-BEND3 complex

    Pitchai, G. P., Hickson, Ian David, Streicher, W., Montoya, Guillermo & Mesa, Pablo, Aug 2016, In: Acta Crystallographica. Section F: Structural Biology and Crystallization Communications Online. 72, 8, p. 646-651 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    A short G1 phase imposes constitutive replication stress and fork remodelling in mouse embryonic stem cells

    Ahuja, A. K., Jodkowska, K., Teloni, F., Bizard, A. H., Zellweger, R., Herrador, R., Ortega, S., Hickson, Ian David, Altmeyer, M., Mendez, J. & Lopes, M., Feb 2016, In: Nature Communications. 7, 11 p., 10660.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published
  7. 2015
  8. Published

    Replication stress activates DNA repair synthesis in mitosis

    Minocherhomji, S., Ying, S., Bjerregaard, Victoria Alexandra, Bursomanno, S., Aleliunaite, A., Wu, Wei, Mankouri, H. W., Shen, H., Liu, Ying & Hickson, Ian David, 10 Dec 2015, In: Nature. 528, 7581, p. 286-90 5 p.

    Research output: Contribution to journalLetterResearchpeer-review

  9. Published

    Interaction of RECQ4 and MCM10 is important for efficient DNA replication origin firing in human cells

    Kliszczak, M., Sedlackova, H., Pitchai, G. P., Streicher, W. W., Krejci, L. & Hickson, Ian David, 1 Dec 2015, In: OncoTarget. 6, 38, p. 40464-79 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    FBH1 Catalyzes Regression of Stalled Replication Forks

    Fugger, K., Mistrik, M., Neelsen, K. J., Yao, Q., Zellweger, R., Kousholt, A. N., Haahr, Peter Thorlund, Chu, W. K., Bartek, J., Lopes, M., Hickson, Ian David & Sørensen, Claus Storgaard, 10 Mar 2015, In: Cell Reports.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Proteome-wide analysis of SUMO2 targets in response to pathological DNA replication stress in human cells

    Bursomanno, S., Beli, P., Khan, A. M., Minocherhomji, S., Wagner, S. A., Bekker-Jensen, Simon Holst, Mailand, Niels, Choudhary, Chunaram, Hickson, Ian David & Liu, Ying, Jan 2015, In: DNA Repair. 25, p. 84-96 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Acute MUS81 depletion leads to replication fork slowing and a constitutive DNA damage response

    Xing, M., Wang, X., Palmai-Pallag, T., Shen, H., Helleday, T., Hickson, Ian David & Ying, S., 2015, In: OncoTarget. 6, 35, p. 37638-37646 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Crystal structure of the Bloom's syndrome helicase indicates a role for the HRDC domain in conformational changes

    Newman, J. A., Savitsky, P., Allerston, C. K., Bizard, A. H., Özer, Ö., Sarlós, K., Liu, Ying, Pardon, E., Steyaert, J., Hickson, Ian David & Gileadi, O., 2015, In: Nucleic Acids Research. 43, 10, p. 5221-35 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    FBH1 influences DNA replication fork stability and homologous recombination through ubiquitylation of RAD51

    Chu, W. K., Payne, M. J., Beli, P., Hanada, K., Choudhary, C. & Hickson, Ian David, 2015, In: Nature Communications. 6, 7 p., 5931.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    PICH promotes sister chromatid disjunction and co-operates with topoisomerase II in mitosis

    Nielsen, Christian Friberg, Huttner, D., Bizard, A. H., Hirano, S., Li, T., Palmai-Pallag, T., Bjerregaard, Victoria Alexandra, Liu, Ying, Nigg, E. A., Wang, L. H. & Hickson, Ian David, 2015, In: Nature Communications. 6, 15 p., 8962.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Regulation of SUMO2 Target Proteins by the Proteasome in Human Cells Exposed to Replication Stress

    Bursomanno, S., McGouran, J. F., Kessler, B. M., Hickson, Ian David & Liu, Ying, 2015, In: Journal of Proteome Research. 14, 4, p. 1687-99 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. 2014
  18. Published

    Mechanistic insight into the interaction of BLM helicase with intra-strand G-quadruplex structures

    Chatterjee, S., Zagelbaum, J., Savitsky, P., Sturzenegger, A., Huttner, D., Janscak, P., Hickson, Ian David, Gileadi, O. & Rothenberg, E., 24 Nov 2014, In: Nature Communications. 5, p. 1-12 12 p., 5556.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Tus-Ter as a tool to study site-specific DNA replication perturbation in eukaryotes

    Larsen, N. B., Hickson, Ian David & Mankouri, H. W., 1 Oct 2014, In: Cell Cycle. 13, 19, p. 2994-8 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Regulation of gene expression by the BLM helicase correlates with the presence of G-quadruplex DNA motifs

    Nguyen, G. H., Tang, W., Robles, A. I., Beyer, R. P., Gray, L. T., Welsh, J. A., Schetter, A. J., Kumamoto, K., Wang, X. W., Hickson, Ian David, Maizels, N., Monnat, R. J. & Harris, C. C., 8 Jul 2014, In: Proceedings of the National Academy of Sciences of the United States of America. 111, 27, p. 9905-10 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    The Dissolution of Double Holliday Junctions

    Bizard, A. H. & Hickson, Ian David, 1 Jul 2014, In: Cold Spring Harbor perspectives in biology. 6, p. 1-16 16 p., a016477.

    Research output: Contribution to journalReviewResearchpeer-review

  22. Published

    Structure-specific endonucleases: guardians of fragile site stability

    Minocherhomji, S. & Hickson, Ian David, May 2014, In: Trends in Cell Biology. 24, 5, p. 321-327 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    The origins and processing of ultra fine anaphase DNA bridges

    Liu, Ying, Nielsen, Christian Friberg, Yao, Q. & Hickson, Ian David, 30 Apr 2014, In: Current Opinion in Genetics & Development. 26C, p. 1-5 5 p.

    Research output: Contribution to journalReviewResearchpeer-review

  24. Published

    Overexpression of DNA ligase III in mitochondria protects cells against oxidative stress and improves mitochondrial DNA base excision repair

    Akbari, M., Keijzers, G., Maynard, S., Scheibye-Knudsen, M., Desler, Claus, Hickson, Ian David & Bohr, Vilhelm, Apr 2014, In: DNA Repair. 16, p. 44-53 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Structural and mechanistic insight into Holliday-junction dissolution by topoisomerase IIIα and RMI1

    Bocquet, N., Bizard, A. H., Abdulrahman, W., Larsen, N. B., Faty, M., Cavadini, S., Bunker, R. D., Kowalczykowski, S. C., Cejka, P., Hickson, Ian David & Thomä, N. H., Mar 2014, In: Nature Structural and Molecular Biology. 21, 3, p. 261-8 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    The Escherichia coli Tus-Ter replication fork barrier causes site-specific DNA replication perturbation in yeast

    Larsen, N. B., Sass, E., Suski, C., Mankouri, H. W. & Hickson, Ian David, 2014, In: Nature Communications. 5, p. 1-10 10 p., 3574.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. 2013
  28. Published

    FBH1 helicase disrupts RAD51 filaments in vitro and modulates homologous recombination in mammalian cells

    Simandlova, J., Zagelbaum, J., Payne, M. J., Chu, W. K., Shevelev, I., Hanada, K., Chatterjee, S., Reid, D. A., Liu, Ying, Janscak, P., Rothenberg, E. & Hickson, Ian David, 22 Nov 2013, In: The Journal of Biological Chemistry. 288, 47, p. 34168-80 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    A Role for BLM in Double-Strand Break Repair Pathway Choice: Prevention of CtIP/Mre11-Mediated Alternative Nonhomologous End-Joining.

    Grabarz, A., Guirouilh-Barbat, J., Barascu, A., Pennarun, G., Genet, D., Rass, E., Germann, S. M., Bertrand, P., Hickson, Ian David & Lopez, B. S., 17 Oct 2013, In: Cell Reports. 5, 1, p. 21-28 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

ID: 17446319