Ian David Hickson
Professor
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Regulation of ETAA1-mediated ATR activation couples DNA replication fidelity and genome stability
Achuthankutty, D., Thakur, R. S., Haahr, Peter Thorlund, Hoffmann, Saskia, Drainas, A. P., Bizard, A. H., Weischenfeldt, Joachim Lütken, Hickson, Ian David & Mailand, Niels, 2019, In: The Journal of Cell Biology. 218, 12, 11 p., 3943.Research output: Contribution to journal › Journal article › Research › peer-review
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A short G1 phase imposes constitutive replication stress and fork remodelling in mouse embryonic stem cells
Ahuja, A. K., Jodkowska, K., Teloni, F., Bizard, A. H., Zellweger, R., Herrador, R., Ortega, S., Hickson, Ian David, Altmeyer, M., Mendez, J. & Lopes, M., Feb 2016, In: Nature Communications. 7, 11 p., 10660.Research output: Contribution to journal › Journal article › Research › peer-review
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Overexpression of DNA ligase III in mitochondria protects cells against oxidative stress and improves mitochondrial DNA base excision repair
Akbari, M., Keijzers, G., Maynard, S., Scheibye-Knudsen, M., Desler, Claus, Hickson, Ian David & Bohr, Vilhelm, Apr 2014, In: DNA Repair. 16, p. 44-53 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Loss of PICH Results in Chromosomal Instability, p53 Activation, and Embryonic Lethality
Albers, E., Sbroggiò, M., Pladevall Morera, David, Bizard, A. H., Avram, Alexandra Ioana, Gonzalez, P., Martin Gonzalez, Javier, Hickson, Ian David & Lopez-Contreras, Andres, 2018, In: Cell Reports. 24, 12, p. 3274-3284 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Yeast as a model system to study RecQ helicase function
Ashton, T. M. & Hickson, Ian David, 2010, In: DNA Repair. 9, 3, p. 303-14 11 p.Research output: Contribution to journal › Review › Research › peer-review
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Pathways for Holliday Junction Processing during Homologous Recombination in Saccharomyces cerevisiae
Ashton, T. M., Mankouri, H. W., Heidenblut, A., McHugh, P. J. & Hickson, Ian David, 1 May 2011, In: Molecular and Cellular Biology. 31, 9, p. 1921-33 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Duplex DNA and BLM regulate gate opening by the human TopoIIIα-RMI1-RMI2 complex
Bakx, J. A. M., Biebricher, A. S., King, G. A., Christodoulis, P., Sarlós, K., Bizard, A. H., Hickson, Ian David, Wuite, G. J. L. & Peterman, E. J. G., 2022, In: Nature Communications. 13, 1, 584.Research output: Contribution to journal › Journal article › Research › peer-review
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RAD51 protects human cells from transcription-replication conflicts
Bhowmick, Rahul, Lerdrup, Mads, Gadi, Sampath Amitash, Rossetti, G. G., Singh, Manika Indrajit, Liu, Ying, Halazonetis, T. D. & Hickson, Ian David, 2022, In: Molecular Cell. 82, 18, p. 3366-3381.e9Research output: Contribution to journal › Journal article › Research › peer-review
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The "enemies within": regions of the genome that are inherently difficult to replicate
Bhowmick, Rahul & Hickson, Ian David, 2017, In: F1000Research. 6, 7 p., 666.Research output: Contribution to journal › Review › Research › peer-review
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Completing genome replication outside of S phase
Bhowmick, Rahul, Hickson, Ian David & Liu, Ying, 2023, In: Molecular Cell. 83, 20, p. 3596-3607 12 p.Research output: Contribution to journal › Review › Research › peer-review
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RAD52 Facilitates Mitotic DNA Synthesis Following Replication Stress
Bhowmick, Rahul, Minocherhomji, S. & Hickson, Ian David, 15 Dec 2016, In: Molecular Cell. 64, 6, p. 1117-1126 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The RIF1-PP1 Axis Controls Abscission Timing in Human Cells
Bhowmick, Rahul, Thakur, R. S., Venegas, A. B., Liu, Ying, Nilsson, Jakob, Barisic, Marin & Hickson, Ian David, 2019, In: Current Biology. 29, 7, p. 1232-1242.e5Research output: Contribution to journal › Journal article › Research › peer-review
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PICH: A DNA Translocase Specially Adapted for Processing Anaphase Bridge DNA
Biebricher, A., Hirano, S., Enzlin, J., Wiechens, N., Streicher, W., Huttner, D., Wang, L., Nigg, E., Owen-Hughes, T., Liu, Ying, Peterman, E., Wuite, G. & Hickson, Ian David, 12 Sep 2013, In: Molecular Cell. 51, 5, p. 691-701 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Detection of Ultrafine Anaphase Bridges
Bizard, A. H., Nielsen, Christian Friberg & Hickson, Ian David, 2018, Genome Instability: Methods and Protocols. Springer, Vol. 1672. p. 495-508 14 p. (Methods in molecular biology (Clifton, N.J.)).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
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Anaphase: a fortune-teller of genomic instability
Bizard, A. H. & Hickson, Ian David, Jun 2018, In: Current Opinion in Cell Biology. 52, p. 112-119 8 p.Research output: Contribution to journal › Review › Research › peer-review
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The Dissolution of Double Holliday Junctions
Bizard, A. H. & Hickson, Ian David, 1 Jul 2014, In: Cold Spring Harbor perspectives in biology. 6, p. 1-16 16 p., a016477.Research output: Contribution to journal › Review › Research › peer-review
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The many lives of type IA topoisomerases
Bizard, A. H. & Hickson, Ian David, 2020, In: Journal of Biological Chemistry. 295, 20, p. 7138-7153 16 p.Research output: Contribution to journal › Review › Research › peer-review
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PICH and TOP3A cooperate to induce positive DNA supercoiling
Bizard, A. H., Allemand, J. F., Hassenkam, Tue, Paramasivam, M., Sarlós, K., Singh, Manika Indrajit & Hickson, Ian David, 2019, In: Nature Structural and Molecular Biology. 26, 4, p. 267-274 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Folate deficiency drives mitotic missegregation of the human FRAXA locus
Bjerregaard, Victoria Alexandra, Garribba, L., McMurray, C. T., Hickson, Ian David & Liu, Ying, 2018, In: Proceedings of the National Academy of Sciences of the United States of America. 115, 51, p. 13003-13008 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The Detection and Analysis of Chromosome Fragile Sites
Bjerregaard, Victoria Alexandra, Özer, Ö., Hickson, Ian David & Liu, Ying, 2018, Genome Instability: Methods and Protocols. Springer, Vol. 1672. p. 471-482 12 p. (Methods in molecular biology (Clifton, N.J.)).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
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Structural and mechanistic insight into Holliday-junction dissolution by topoisomerase IIIα and RMI1
Bocquet, N., Bizard, A. H., Abdulrahman, W., Larsen, N. B., Faty, M., Cavadini, S., Bunker, R. D., Kowalczykowski, S. C., Cejka, P., Hickson, Ian David & Thomä, N. H., Mar 2014, In: Nature Structural and Molecular Biology. 21, 3, p. 261-8 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The ZGRF1 Helicase Promotes Recombinational Repair of Replication-Blocking DNA Damage in Human Cells
Brannvoll, A., Xue, X., Kwon, Y., Kompocholi, Smaragda, Simonsen, Anne Katrine Wrist, Bagge, Keerthana Stine Viswalingam, Gonzalez, L., Hickson, Ian David, Østergaard, Vibe Hallundbæk, Mankouri, H. W., Sung, P. & Lisby, Michael, 2020, In: Cell Reports. 32, 1, 25 p., 107849.Research output: Contribution to journal › Journal article › Research › peer-review
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Proteome-wide analysis of SUMO2 targets in response to pathological DNA replication stress in human cells
Bursomanno, S., Beli, P., Khan, A. M., Minocherhomji, S., Wagner, S. A., Bekker-Jensen, Simon Holst, Mailand, Niels, Choudhary, Chunaram, Hickson, Ian David & Liu, Ying, Jan 2015, In: DNA Repair. 25, p. 84-96 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Regulation of SUMO2 Target Proteins by the Proteasome in Human Cells Exposed to Replication Stress
Bursomanno, S., McGouran, J. F., Kessler, B. M., Hickson, Ian David & Liu, Ying, 2015, In: Journal of Proteome Research. 14, 4, p. 1687-99 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Tumour predisposition and cancer syndromes as models to study gene–environment interactions
Carbone, M., Arron, S. T., Beutler, B., Bononi, A., Cavenee, W., Cleaver, J. E., Croce, C. M., D’Andrea, A., Foulkes, W. D., Gaudino, G., Groden, J. L., Henske, E. P., Hickson, I. D., Hwang, P. M., Kolodner, R. D., Mak, T. W., Malkin, D., Monnat, R. J., Novelli, F., Pass, H. I. & 3 others, , 2020, In: Nature Reviews Cancer. 20, p. 533–549Research output: Contribution to journal › Journal article › Research › peer-review
ID: 17446319
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LIFESTAT – Living with statins: An interdisciplinary project on the use of statins as a cholesterol-lowering treatment and for cardiovascular risk reduction
Research output: Contribution to journal › Journal article › Research › peer-review
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272
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A novel TPR-BEN domain interaction mediates PICH-BEND3 association
Research output: Contribution to journal › Journal article › Research › peer-review
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239
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Knotty Problems during Mitosis: Mechanistic Insight into the Processing of Ultrafine DNA Bridges in Anaphase
Research output: Contribution to journal › Journal article › Research › peer-review
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