Ian David Hickson

Ian David Hickson

Professor


  1. Published

    Human cancer cells utilize mitotic DNA synthesis to resist replication stress at telomeres regardless of their telomere maintenance mechanism

    Özer, Ö., Bhowmick, Rahul, Liu, Ying & Hickson, Ian David, 2018, In: OncoTarget. 9, 22, p. 15836-15846 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    Pathways for maintenance of telomeres and common fragile sites during DNA replication stress

    Özer, Ö. & Hickson, Ian David, 2018, In: Open Biology. 8, 4, 11 p., 180018.

    Research output: Contribution to journalReviewResearchpeer-review

  3. Published

    DNA replication stress and its impact on chromosome segregation and tumorigenesis

    Zhang, B. N., Bueno Venegas, A., Hickson, Ian David & Chu, W. K., 2019, In: Seminars in Cancer Biology. 55, p. 61-69

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    MUS81 promotes common fragile site expression

    Ying, S., Minocherhomji, S., Chan, K. L., Palmai-Pallag, T., Chu, W. K., Wass, T. A., Mankouri, H. W., Liu, Ying & Hickson, Ian David, Aug 2013, In: Nature Cell Biology. 15, 8, p. 1001-1007 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Fanconi anaemia proteins are associated with sister chromatid bridging in mitosis

    Ying, S. & Hickson, Ian David, 1 Apr 2011, In: U H O D. 93, 4, p. 440-5 6 p.

    Research output: Contribution to journalReviewResearchpeer-review

  6. Published

    Human topoisomerase IIIalpha is a single-stranded DNA decatenase that is stimulated by BLM and RMI1

    Yang, J., Bachrati, C. Z., Ou, J., Hickson, Ian David & Brown, G. W., 2010, In: Journal of Biological Chemistry. 285, 28, p. 21426-36 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    BLM and RMI1 Alleviate RPA Inhibition of TopoIIIa Decatenase Activity

    Yang, J., Bachrati, C. Z., Hickson, Ian David & Brown, G. W., Jul 2012, In: P L o S One. 7, 7, p. e41208

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Replication Stress Induces ATR/CHK1-Dependent Nonrandom Segregation of Damaged Chromosomes

    Xing, M., Zhang, F., Liao, H., Chen, S., Che, L., Wang, X., Bao, Z., Ji, F., Chen, G., Zhang, H., Li, W., Chen, Z., Liu, Ying, Hickson, Ian David, Shen, H. & Ying, S., 2020, In: Molecular Cell. 78, 4, p. 714-724.e5

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Acute MUS81 depletion leads to replication fork slowing and a constitutive DNA damage response

    Xing, M., Wang, X., Palmai-Pallag, T., Shen, H., Helleday, T., Hickson, Ian David & Ying, S., 2015, In: OncoTarget. 6, 35, p. 37638-37646 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    The prevention and resolution of DNA replication–transcription conflicts in eukaryotic cells

    Wu, Wei, Hickson, Ian David & Liu, Ying, 2020, In: Genome Instability & Disease. 1, 3, p. 114–128 15 p.

    Research output: Contribution to journalReviewResearchpeer-review

  11. Published

    RTEL1 suppresses G-quadruplex-associated R-loops at difficult-to-replicate loci in the human genome

    Wu, Wei, Bhowmick, Rahul, Vogel, Ivan, Özer, Ö., Ghisays, F., Thakur, R. S., Sanchez de Leon, E., Richter, P. H., Ren, L., Petrini, J. H., Hickson, Ian David & Liu, Ying, 2020, In: Nature Structural & Molecular Biology. 27, 5, p. 424-437 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    A role for the fission yeast Rqh1 helicase in chromosome segregation

    Win, T. Z., Mankouri, H. W., Hickson, Ian David & Wang, S., 15 Dec 2005, In: Journal of Cell Science. 118, Pt 24, p. 5777-84 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Inducible Degradation of the Human SMC5/6 Complex Reveals an Essential Role Only during Interphase

    Venegas, A. B., Natsume, T., Kanemaki, M. & Hickson, Ian David, 2020, In: Cell Reports. 31, 3, 20 p., 107533.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    MicroRNA-449a Inhibits Triple Negative Breast Cancer by Disturbing DNA Repair and Chromatid Separation

    Vajen, B., Bhowmick, Rahul, Greiwe, L., Schäffer, V., Eilers, M., Reinkens, T., Stalke, A., Schmidt, G., Fiedler, J., Thum, T., Deluca, D. S., Hickson, Ian David, Schlegelberger, B., Illig, T. & Skawran, B., 2022, In: International Journal of Molecular Sciences. 23, 9, 5131.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Chromosome instability syndromes

    Taylor, A. M. R., Rothblum-Oviatt, C., Ellis, N. A., Hickson, Ian David, Meyer, S., Crawford, T. O., Smogorzewska, A., Pietrucha, B., Weemaes, C. & Stewart, G. S., 2019, In: Nature Reviews. Disease Primers. 5, 20 p., 64.

    Research output: Contribution to journalReviewResearchpeer-review

  16. Published

    Interaction between the helicases genetically linked to Fanconi anemia group J and Bloom's syndrome

    Suhasini, A. N., Rawtani, N. A., Wu, Y., Sommers, J. A., Sharma, S., Mosedale, G., North, P. S., Cantor, S. B., Hickson, Ian David & Brosh, R. M., 16 Feb 2011, In: E M B O Journal. 30, 4, p. 692-705 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    PICH acts as a force-dependent nucleosome remodeler

    Spakman, D., Clement, T. V. M., Biebricher, A. S., King, G. A., Singh, Manika Indrajit, Hickson, Ian David, Peterman, E. J. G. & Wuite, G. J. L., 2022, In: Nature Communications. 13, 7277.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    TRAIP drives replisome disassembly and mitotic DNA repair synthesis at sites of incomplete DNA replication

    Sonneville, R., Bhowmick, Rahul, Hoffmann, Saskia, Mailand, Niels, Hickson, Ian David & Labib, K., 2019, In: eLife. 8, 19 p., e48686.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    FBH1 helicase disrupts RAD51 filaments in vitro and modulates homologous recombination in mammalian cells

    Simandlova, J., Zagelbaum, J., Payne, M. J., Chu, W. K., Shevelev, I., Hanada, K., Chatterjee, S., Reid, D. A., Liu, Ying, Janscak, P., Rothenberg, E. & Hickson, Ian David, 22 Nov 2013, In: The Journal of Biological Chemistry. 288, 47, p. 34168-80 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Viscoelastic Capillary Flow Cytometry

    Serhatlioglu, M., Jensen, E. A., Niora, M., Hansen, A. T., Nielsen, Christian Friberg, Jansman, M. M. T., Hosta-rigau, L., Dziegiel, Morten Hanefeld, Berg-sørensen, K., Hickson, Ian David & Kristensen, A., 2023, In: Advanced NanoBiomed Research. 3, 2, 2200137.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Development of a fiber-based microfluidic flow cytometry platform using viscoelastic fluids for polydisperse particle suspensions

    Serhatlioglu, M., Jensen, E. A., Niora, M., Hansen, A. T., Nielsen, Christian Friberg, Theresia Jansman, M. M., Hosta-Rigau, L., Dziegiel, Morten Hanefeld, Berg-Sørensen, K., Hickson, Ian David & Kristensen, A., 2022, In: Proceedings of SPIE - The International Society for Optical Engineering. 12198, 9 p., 1219802.

    Research output: Contribution to journalConference articleResearchpeer-review

  22. Published

    Knotty Problems during Mitosis: Mechanistic Insight into the Processing of Ultrafine DNA Bridges in Anaphase

    Sarlós, K., Biebricher, A., Petermann, E. J. G., Wuite, G. J. L. & Hickson, Ian David, 2017, In: Cold Spring Harbor Laboratory. Symposia on Quantitative Biology. 82, p. 187-195

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Reconstitution of anaphase DNA bridge recognition and disjunction

    Sarlós, K., Biebricher, A. S., Bizard, A. H., Bakx, J. A. M., Ferreté-Bonastre, A. G., Modesti, M., Paramasivam, M., Yao, Q., Peterman, E. J. G., Wuite, G. J. L. & Hickson, Ian David, 2018, In: Nature Structural and Molecular Biology. 25, 9, p. 868-876 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Synthesis and SAR studies of 5-(pyridin-4-yl)-1,3,4-thiadiazol-2-amine derivatives as potent inhibitors of Bloom helicase

    Rosenthal, A. S., Dexheimer, T. S., Gileadi, O., Nguyen, G. H., Chu, W. K., Hickson, Ian David, Jadhav, A., Simeonov, A. & Maloney, D. J., 15 Oct 2013, In: Bioorganic & Medicinal Chemistry Letters. 23, 20, p. 5660-6 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Potential biomarkers of DNA replication stress in cancer

    Ren, L., Chen, L., Wu, Wei, Garribba, L., Tian, H., Liu, Z., Vogel, Ivan, Li, C., Hickson, Ian David & Liu, Ying, 2017, In: OncoTarget. 8, 23, p. 36996-37008 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

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