Ian David Hickson
Professor
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Human cancer cells utilize mitotic DNA synthesis to resist replication stress at telomeres regardless of their telomere maintenance mechanism
Özer, Ö., Bhowmick, Rahul, Liu, Ying & Hickson, Ian David, 2018, In: OncoTarget. 9, 22, p. 15836-15846 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Pathways for maintenance of telomeres and common fragile sites during DNA replication stress
Özer, Ö. & Hickson, Ian David, 2018, In: Open Biology. 8, 4, 11 p., 180018.Research output: Contribution to journal › Review › Research › peer-review
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DNA replication stress and its impact on chromosome segregation and tumorigenesis
Zhang, B. N., Bueno Venegas, A., Hickson, Ian David & Chu, W. K., 2019, In: Seminars in Cancer Biology. 55, p. 61-69Research output: Contribution to journal › Journal article › Research › peer-review
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MUS81 promotes common fragile site expression
Ying, S., Minocherhomji, S., Chan, K. L., Palmai-Pallag, T., Chu, W. K., Wass, T. A., Mankouri, H. W., Liu, Ying & Hickson, Ian David, Aug 2013, In: Nature Cell Biology. 15, 8, p. 1001-1007 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Fanconi anaemia proteins are associated with sister chromatid bridging in mitosis
Ying, S. & Hickson, Ian David, 1 Apr 2011, In: U H O D. 93, 4, p. 440-5 6 p.Research output: Contribution to journal › Review › Research › peer-review
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Human topoisomerase IIIalpha is a single-stranded DNA decatenase that is stimulated by BLM and RMI1
Yang, J., Bachrati, C. Z., Ou, J., Hickson, Ian David & Brown, G. W., 2010, In: Journal of Biological Chemistry. 285, 28, p. 21426-36 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
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BLM and RMI1 Alleviate RPA Inhibition of TopoIIIa Decatenase Activity
Yang, J., Bachrati, C. Z., Hickson, Ian David & Brown, G. W., Jul 2012, In: P L o S One. 7, 7, p. e41208Research output: Contribution to journal › Journal article › Research › peer-review
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Replication Stress Induces ATR/CHK1-Dependent Nonrandom Segregation of Damaged Chromosomes
Xing, M., Zhang, F., Liao, H., Chen, S., Che, L., Wang, X., Bao, Z., Ji, F., Chen, G., Zhang, H., Li, W., Chen, Z., Liu, Ying, Hickson, Ian David, Shen, H. & Ying, S., 2020, In: Molecular Cell. 78, 4, p. 714-724.e5Research output: Contribution to journal › Journal article › Research › peer-review
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Acute MUS81 depletion leads to replication fork slowing and a constitutive DNA damage response
Xing, M., Wang, X., Palmai-Pallag, T., Shen, H., Helleday, T., Hickson, Ian David & Ying, S., 2015, In: OncoTarget. 6, 35, p. 37638-37646 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The prevention and resolution of DNA replication–transcription conflicts in eukaryotic cells
Wu, Wei, Hickson, Ian David & Liu, Ying, 2020, In: Genome Instability & Disease. 1, 3, p. 114–128 15 p.Research output: Contribution to journal › Review › Research › peer-review
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RTEL1 suppresses G-quadruplex-associated R-loops at difficult-to-replicate loci in the human genome
Wu, Wei, Bhowmick, Rahul, Vogel, Ivan, Özer, Ö., Ghisays, F., Thakur, R. S., Sanchez de Leon, E., Richter, P. H., Ren, L., Petrini, J. H., Hickson, Ian David & Liu, Ying, 2020, In: Nature Structural & Molecular Biology. 27, 5, p. 424-437 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
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A role for the fission yeast Rqh1 helicase in chromosome segregation
Win, T. Z., Mankouri, H. W., Hickson, Ian David & Wang, S., 15 Dec 2005, In: Journal of Cell Science. 118, Pt 24, p. 5777-84 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Inducible Degradation of the Human SMC5/6 Complex Reveals an Essential Role Only during Interphase
Venegas, A. B., Natsume, T., Kanemaki, M. & Hickson, Ian David, 2020, In: Cell Reports. 31, 3, 20 p., 107533.Research output: Contribution to journal › Journal article › Research › peer-review
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MicroRNA-449a Inhibits Triple Negative Breast Cancer by Disturbing DNA Repair and Chromatid Separation
Vajen, B., Bhowmick, Rahul, Greiwe, L., Schäffer, V., Eilers, M., Reinkens, T., Stalke, A., Schmidt, G., Fiedler, J., Thum, T., Deluca, D. S., Hickson, Ian David, Schlegelberger, B., Illig, T. & Skawran, B., 2022, In: International Journal of Molecular Sciences. 23, 9, 5131.Research output: Contribution to journal › Journal article › Research › peer-review
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Chromosome instability syndromes
Taylor, A. M. R., Rothblum-Oviatt, C., Ellis, N. A., Hickson, Ian David, Meyer, S., Crawford, T. O., Smogorzewska, A., Pietrucha, B., Weemaes, C. & Stewart, G. S., 2019, In: Nature Reviews. Disease Primers. 5, 20 p., 64.Research output: Contribution to journal › Review › Research › peer-review
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Interaction between the helicases genetically linked to Fanconi anemia group J and Bloom's syndrome
Suhasini, A. N., Rawtani, N. A., Wu, Y., Sommers, J. A., Sharma, S., Mosedale, G., North, P. S., Cantor, S. B., Hickson, Ian David & Brosh, R. M., 16 Feb 2011, In: E M B O Journal. 30, 4, p. 692-705 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
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PICH acts as a force-dependent nucleosome remodeler
Spakman, D., Clement, T. V. M., Biebricher, A. S., King, G. A., Singh, Manika Indrajit, Hickson, Ian David, Peterman, E. J. G. & Wuite, G. J. L., 2022, In: Nature Communications. 13, 7277.Research output: Contribution to journal › Journal article › Research › peer-review
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TRAIP drives replisome disassembly and mitotic DNA repair synthesis at sites of incomplete DNA replication
Sonneville, R., Bhowmick, Rahul, Hoffmann, Saskia, Mailand, Niels, Hickson, Ian David & Labib, K., 2019, In: eLife. 8, 19 p., e48686.Research output: Contribution to journal › Journal article › Research › peer-review
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FBH1 helicase disrupts RAD51 filaments in vitro and modulates homologous recombination in mammalian cells
Simandlova, J., Zagelbaum, J., Payne, M. J., Chu, W. K., Shevelev, I., Hanada, K., Chatterjee, S., Reid, D. A., Liu, Ying, Janscak, P., Rothenberg, E. & Hickson, Ian David, 22 Nov 2013, In: The Journal of Biological Chemistry. 288, 47, p. 34168-80 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Viscoelastic Capillary Flow Cytometry
Serhatlioglu, M., Jensen, E. A., Niora, M., Hansen, A. T., Nielsen, Christian Friberg, Jansman, M. M. T., Hosta-rigau, L., Dziegiel, Morten Hanefeld, Berg-sørensen, K., Hickson, Ian David & Kristensen, A., 2023, In: Advanced NanoBiomed Research. 3, 2, 2200137.Research output: Contribution to journal › Journal article › Research › peer-review
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Development of a fiber-based microfluidic flow cytometry platform using viscoelastic fluids for polydisperse particle suspensions
Serhatlioglu, M., Jensen, E. A., Niora, M., Hansen, A. T., Nielsen, Christian Friberg, Theresia Jansman, M. M., Hosta-Rigau, L., Dziegiel, Morten Hanefeld, Berg-Sørensen, K., Hickson, Ian David & Kristensen, A., 2022, In: Proceedings of SPIE - The International Society for Optical Engineering. 12198, 9 p., 1219802.Research output: Contribution to journal › Conference article › Research › peer-review
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Knotty Problems during Mitosis: Mechanistic Insight into the Processing of Ultrafine DNA Bridges in Anaphase
Sarlós, K., Biebricher, A., Petermann, E. J. G., Wuite, G. J. L. & Hickson, Ian David, 2017, In: Cold Spring Harbor Laboratory. Symposia on Quantitative Biology. 82, p. 187-195Research output: Contribution to journal › Journal article › Research › peer-review
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Reconstitution of anaphase DNA bridge recognition and disjunction
Sarlós, K., Biebricher, A. S., Bizard, A. H., Bakx, J. A. M., Ferreté-Bonastre, A. G., Modesti, M., Paramasivam, M., Yao, Q., Peterman, E. J. G., Wuite, G. J. L. & Hickson, Ian David, 2018, In: Nature Structural and Molecular Biology. 25, 9, p. 868-876 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Synthesis and SAR studies of 5-(pyridin-4-yl)-1,3,4-thiadiazol-2-amine derivatives as potent inhibitors of Bloom helicase
Rosenthal, A. S., Dexheimer, T. S., Gileadi, O., Nguyen, G. H., Chu, W. K., Hickson, Ian David, Jadhav, A., Simeonov, A. & Maloney, D. J., 15 Oct 2013, In: Bioorganic & Medicinal Chemistry Letters. 23, 20, p. 5660-6 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Potential biomarkers of DNA replication stress in cancer
Ren, L., Chen, L., Wu, Wei, Garribba, L., Tian, H., Liu, Z., Vogel, Ivan, Li, C., Hickson, Ian David & Liu, Ying, 2017, In: OncoTarget. 8, 23, p. 36996-37008 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 17446319
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LIFESTAT – Living with statins: An interdisciplinary project on the use of statins as a cholesterol-lowering treatment and for cardiovascular risk reduction
Research output: Contribution to journal › Journal article › Research › peer-review
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272
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A novel TPR-BEN domain interaction mediates PICH-BEND3 association
Research output: Contribution to journal › Journal article › Research › peer-review
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239
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Knotty Problems during Mitosis: Mechanistic Insight into the Processing of Ultrafine DNA Bridges in Anaphase
Research output: Contribution to journal › Journal article › Research › peer-review
Published