Simon Holst Bekker-Jensen

Simon Holst Bekker-Jensen

Professor

Member of:

ORCID: 0000-0002-7308-4597

Publication year:
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51 - 75 out of 78Page size: 25
  1. 2013
  2. Published

    RNF111/Arkadia is a SUMO-targeted ubiquitin ligase that facilitates the DNA damage response

    Poulsen, S. L., Hansen, R. K., Wagner, S. A., van Cuijk, L., van Belle, G. J., Streicher, W., Wikström, M., Choudhary, Chunaram, Houtsmuller, A. B., Marteijn, J. A., Bekker-Jensen, Simon Holst & Mailand, Niels, 10 Jun 2013, In: Journal of Cell Biology. 201, 6, p. 797-807 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Regulation of PCNA-protein interactions for genome stability

    Mailand, Niels, Gibbs-Seymour, I. & Bekker-Jensen, Simon Holst, May 2013, In: Nature Reviews. Molecular Cell Biology. 14, 5, p. 269-82 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    The deubiquitylating enzyme USP44 counteracts the DNA double-strand break response mediated by the RNF8 and RNF168 ubiquitin ligases

    Mosbech, A., Lukas, Claudia, Bekker-Jensen, Simon Holst & Mailand, Niels, 24 Apr 2013, In: Journal of Biological Chemistry. 288, p. 16579-16587 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. 2012
  6. Published

    Histone displacement during nucleotide excision repair

    Dinant, C., Bartek, J. & Bekker-Jensen, Simon Holst, 17 Oct 2012, In: International Journal of Molecular Sciences (Online). 13, 10, p. 13322-13337 16 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass

    Povlsen, L. K., Beli, P., Wagner, S. A., Poulsen, S. L., Sylvestersen, K. B., Poulsen, J. W., Nielsen, Michael Lund, Bekker-Jensen, Simon Holst, Mailand, Niels & Choudhary, Chunaram, Oct 2012, In: Nature Cell Biology. 14, 10, p. 1089-98 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Ubiquitin and the DNA damage response: a new handle on histones

    Bekker-Jensen, Simon Holst & Mailand, Niels, 1 Sep 2012, In: Cell Cycle. 11, 17, p. 3153 1 p.

    Research output: Contribution to journal › Comment/debate › Research › peer-review

  9. Published

    TRIP12 and UBR5 Suppress Spreading of Chromatin Ubiquitylation at Damaged Chromosomes

    Gudjónsson, Thorkell, Altmeyer, M. F., Savic, V., Toledo Lazaro, L. I., Dinant, C., Grøfte, M., Bartkova, J., Poulsen, M., Oka, Y., Bekker-Jensen, Simon Holst, Mailand, Niels, Neumann, B., Heriche, J., Shearer, R., Saunders, D., Bartek, J., Lukas, Jiri & Lukas, Claudia, 17 Aug 2012, In: Cell. 150, 4, p. 697-709 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    A new non-catalytic role for ubiquitin ligase RNF8 in unfolding higher-order chromatin structure

    Luijsterburg, M. S., Acs, K., Ackermann, L., Wiegant, W. W., Bekker-Jensen, Simon Holst, Larsen, D. H., Khanna, K. K., van Attikum, H., Mailand, Niels & Dantuma, N. P., 2012, In: E M B O Journal. 31, 11, p. 2511-27 17 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    DNA damage-inducible SUMOylation of HERC2 promotes RNF8 binding via a novel SUMO-binding Zinc finger

    Danielsen, J. M. R., Povlsen, L. K., Villumsen, B. H., Streicher, W., Nilsson, Jakob, Wikström, M., Bekker-Jensen, Simon Holst & Mailand, Niels, 2012, In: Journal of Cell Biology. 197, 2, p. 179-87 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    DVC1 (C1orf124) is a DNA damage-targeting p97 adaptor that promotes ubiquitin-dependent responses to replication blocks

    Mosbech, A., Gibbs-Seymour, I., Kagias, K., Thorslund, T., Beli, P., Povlsen, L., Nielsen, S. V., Smedegaard, S., Sedgwick, G., Lukas, Claudia, Hartmann-Petersen, Rasmus, Lukas, Jiri, Choudhary, Chunaram, Pocock, R. D. J., Bekker-Jensen, Simon Holst & Mailand, Niels, 2012, In: Nature Structural and Molecular Biology. 19, 11, p. 1084-92 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Human RNF169 is a negative regulator of the ubiquitin-dependent response to DNA double-strand breaks

    Poulsen, M., Lukas, C., Lukas, J., Bekker-Jensen, Simon Holst & Mailand, Niels, 2012, In: Journal of Cell Biology. 197, 2, p. 189-99 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    ICLs: a chicken without an egg

    Bekker-Jensen, Simon Holst & Mailand, Niels, 2012, In: Nature Reviews. Molecular Cell Biology. 13, 6, p. 342

    Research output: Contribution to journal › Review › Research › peer-review

  15. Published

    RNF8 and RNF168 but not HERC2 are required for DNA damage-induced ubiquitylation in chicken DT40 cells

    Østergaard, Vibe Hallundbæk, Pentzold, C., Pedersen, R. T., Iosif, S., Alpi, A., Bekker-Jensen, Simon Holst, Mailand, Niels & Lisby, Michael, 2012, In: D N A Repair. 11, 11, p. 892–905 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    The Ubiquitin Ligase XIAP Recruits LUBAC for NOD2 Signaling in Inflammation and Innate Immunity

    Damgaard, R. B., Nachbur, U., Yabal, M., Wong, W. W., Fiil, Berthe Katrine, Kastirr, M., Rieser, E., Rickard, J. A., Bankovacki, A., Peschel, C., Ruland, J., Bekker-Jensen, Simon Holst, Mailand, Niels, Kaufmann, T., Strasser, A., Walczak, H., Silke, J., Jost, P. J. & Gyrd-Hansen, Mads, 2012, In: Molecular Cell. 46, 6, p. 746-58 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. 2011
  18. Published

    The ubiquitin- and SUMO-dependent signaling response to DNA double-strand breaks

    Bekker-Jensen, Simon Holst & Mailand, Niels, 12 Jun 2011, In: FEBS Letters. 585, p. 2914-2919 6 p.

    Research output: Contribution to journal › Review › Research › peer-review

  19. Published

    53BP1 nuclear bodies form around DNA lesions generated by mitotic transmission of chromosomes under replication stress

    Lukas, Claudia, Savic, V., Bekker-Jensen, Simon Holst, Doil, C., Neumann, B., Pedersen, R. S., Grøfte, M., Chan, K. L., Hickson, Ian David, Bartek, J. & Lukas, Jiri, 1 Mar 2011, In: Nature Cell Biology. 13, 3, p. 243-53 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Mass spectrometric analysis of lysine ubiquitylation reveals promiscuity at site level

    Danielsen, J. M. R., Sylvestersen, K. B., Bekker-Jensen, Simon Holst, Szklarczyk, D., Poulsen, J. W., Horn, H., Jensen, Lars Juhl, Mailand, Niels & Nielsen, Michael Lund, 1 Mar 2011, In: Molecular and Cellular Proteomics. 10, 3, p. M110.003590

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. 2010
  22. Published

    Assembly and function of DNA double-strand break repair foci in mammalian cells

    Bekker-Jensen, Simon Holst & Mailand, Niels, 10 Dec 2010, In: D N A Repair. 9, 12, p. 1219-28 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. HERC2 coordinates ubiquitin-dependent assembly of DNA repair factors on damaged chromosomes

    Bekker-Jensen, Simon Holst, Danielsen, J. M. R., Fugger, K., Gromova, I., Nerstedt, A., Bartek, J., Lukas, Jiri & Mailand, Niels, 2010, In: Nature Cell Biology. 12, 1, p. 80-6; sup pp 1-12

    Research output: Contribution to journal › Letter › Research › peer-review

  24. 2009
  25. Published

    Mislocalization of the MRN complex prevents ATR signaling during adenovirus infection

    Carson, C. T., Orazio, N. I., Lee, D. V., Suh, J., Bekker-Jensen, Simon Holst, Araujo, F. D., Lakdawala, S. S., Lilley, C. E., Bartek, J., Lukas, Jiri & Weitzman, M. D., 2009, In: EMBO Journal. 28, 6, p. 652-62 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Nucleotide excision repair-induced H2A ubiquitination is dependent on MDC1 and RNF8 and reveals a universal DNA damage response

    Marteijn, J. A., Bekker-Jensen, Simon Holst, Mailand, Niels, Lans, H., Schwertman, P., Gourdin, A. M., Dantuma, N. P., Lukas, Jiri & Vermeulen, W., 2009, In: Journal of Cell Biology. 186, 6, p. 835-47 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. RNF168 binds and amplifies ubiquitin conjugates on damaged chromosomes to allow accumulation of repair proteins

    Doil, C., Mailand, Niels, Bekker-Jensen, Simon Holst, Ménard, Patrice, Larsen, D. H., Pepperkok, R., Ellenberg, J., Panier, S., Durocher, D., Bartek, J., Lukas, Jiri & Lukas, Claudia, 2009, In: Cell. 136, 3, p. 435-46 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. USP7 counteracts SCFbetaTrCP- but not APCCdh1-mediated proteolysis of Claspin

    Faustrup, H., Bekker-Jensen, Simon Holst, Bartek, J., Lukas, Jiri & Mailand, Niels, 2009, In: Journal of Cell Biology. 184, 1, p. 13-9 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. 2008

  30. Phosphorylation of SDT repeats in the MDC1 N terminus triggers retention of NBS1 at the DNA damage-modified chromatin

    Melander, F., Bekker-Jensen, Simon Holst, Falck, J., Bartek, J., Mailand, Niels & Lukas, Jiri, 21 Apr 2008, In: Journal of Cell Biology. 181, 2, p. 213-26 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. 2007
  32. Published

    Human Xip1 (C2orf13) is a novel regulator of cellular responses to DNA strand breaks

    Bekker-Jensen, Simon Holst, Fugger, K., Danielsen, J. R., Gromova, I., Sehested, M., Celis, J., Bartek, J., Lukas, Jiri & Mailand, Niels, 6 Jul 2007, In: Journal of Biological Chemistry. 282, 27, p. 19638-43 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

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