Inducible Degradation of the Human SMC5/6 Complex Reveals an Essential Role Only during Interphase

Research output: Contribution to journalJournal articleResearchpeer-review

Venegas et al. employ an auxin-inducible degron system for different subunits of the SMC5/6 complex to interrogate the short- and long-term effects of SMC5/6 impairment in human cells. Degradation of SMC5/6’s subunits at different cell cycle stages places the essential role of the complex during S phase.

Original languageEnglish
Article number107533
JournalCell Reports
Volume31
Issue number3
Number of pages20
ISSN2211-1247
DOIs
Publication statusPublished - 2020

Number of downloads are based on statistics from Google Scholar and www.ku.dk


No data available

ID: 240143048