Inducible Degradation of the Human SMC5/6 Complex Reveals an Essential Role Only during Interphase
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Inducible Degradation of the Human SMC5/6 Complex Reveals an Essential Role Only during Interphase. / Venegas, Andrés Bueno; Natsume, Toyoaki; Kanemaki, Masato; Hickson, Ian D.
In: Cell Reports, Vol. 31, No. 3, 107533, 2020.Research output: Contribution to journal › Journal article › Research › peer-review
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TY - JOUR
T1 - Inducible Degradation of the Human SMC5/6 Complex Reveals an Essential Role Only during Interphase
AU - Venegas, Andrés Bueno
AU - Natsume, Toyoaki
AU - Kanemaki, Masato
AU - Hickson, Ian D.
PY - 2020
Y1 - 2020
N2 - Venegas et al. employ an auxin-inducible degron system for different subunits of the SMC5/6 complex to interrogate the short- and long-term effects of SMC5/6 impairment in human cells. Degradation of SMC5/6’s subunits at different cell cycle stages places the essential role of the complex during S phase.
AB - Venegas et al. employ an auxin-inducible degron system for different subunits of the SMC5/6 complex to interrogate the short- and long-term effects of SMC5/6 impairment in human cells. Degradation of SMC5/6’s subunits at different cell cycle stages places the essential role of the complex during S phase.
U2 - 10.1016/j.celrep.2020.107533
DO - 10.1016/j.celrep.2020.107533
M3 - Journal article
C2 - 32320646
AN - SCOPUS:85083288723
VL - 31
JO - Cell Reports
JF - Cell Reports
SN - 2211-1247
IS - 3
M1 - 107533
ER -
ID: 240143048