Damage and Repair

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  1. Published

    Human exonuclease 1 (EXO1) regulatory functions in DNA replication with putative roles in cancer

    Keijzers, G., Bakula, Daniela Janina, Petr, Michael Angelo, Madsen, N. G. K., Teklu, Amanuel Abraha, Mkrtchyan, Garik, Osborne, Brenna & Scheibye-Knudsen, Morten, 2019, In: International Journal of Molecular Sciences . 20, 1, 15 p., 74.

    Research output: Contribution to journal › Review › Research › peer-review

  2. Published

    Human skeletal muscle fibroblasts stimulate in vitro myogenesis and in vivo muscle regeneration

    Mackey, Abigail, Magnan, M., Chazaud, B. & Kjær, Michael, 2017, In: The Journal of Physiology. 595, 15, p. 5115-5127 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Human topoisomerase IIIalpha is a single-stranded DNA decatenase that is stimulated by BLM and RMI1

    Yang, J., Bachrati, C. Z., Ou, J., Hickson, Ian David & Brown, G. W., 2010, In: Journal of Biological Chemistry. 285, 28, p. 21426-36 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Hyposalivation and Poor Dental Health Status Are Potential Correlates of Age-Related Cognitive Decline in Late Midlife in Danish Men

    Sørensen, Christiane Elisabeth, Hansen, N. L., Mortensen, Erik Lykke, Lauritzen, Martin, Osler, Merete & Pedersen, Anne Marie Lynge, 2018, In: Frontiers in Aging Neuroscience. 10, p. 1-7 7 p., 10.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    ICLs: a chicken without an egg

    Bekker-Jensen, Simon Holst & Mailand, Niels, 2012, In: Nature Reviews. Molecular Cell Biology. 13, 6, p. 342

    Research output: Contribution to journal › Review › Research › peer-review

  6. Published

    Ibuprofen alters human testicular physiology to produce a state of compensated hypogonadism

    Kristensen, D. M., Desdoits-Lethimonier, C., Mackey, Abigail, Dalgaard, M. D., De Masi, F., Munkbøl, C. H., Styrishave, Bjarne, Antignac, J., Le Bizec, B., Platel, C., Hay-Schmidt, Anders, Jensen, T. K., Lesné, L., Mazaud-Guittot, S., Kristiansen, Karsten, Brunak, Søren, Kjær, Michael, Juul, Anders & Jégou, B., 2018, In: Proceedings of the National Academy of Sciences of the United States of America. 115, 4, p. e715-e724 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Identification of athletes at future risk of anterior cruciate ligament ruptures by neuromuscular screening

    Zebis, M. K., Andersen, L. L., Bencke, J., Kjær, Michael & Aagaard, P., 2009, In: American Journal of Sports Medicine. 37, 10, p. 1967-73 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Immobilization Decreases FOXO3a Phosphorylation and Increases Autophagy-Related Gene and Protein Expression in Human Skeletal Muscle

    Møller, A. B., Vendelbo, M. H., Schjerling, Peter, Couppé, Christian, Møller, N., Kjær, Michael, Hansen, M. & Jessen, N., 14 Jun 2019, In: Frontiers in Physiology. 10, 14 p., 736.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Impact of GH administration on athletic performance in healthy young adults: A systematic review and meta-analysis of placebo-controlled trials

    Hermansen, K., Bengtsen, M., Kjær, Michael, Vestergaard, P. & Jørgensen, J. O. L., 2017, In: Growth Hormone & I G F Research. 34, p. 38-44

    Research output: Contribution to journal › Review › Research › peer-review

  10. Published

    Impact of bacterial infections on aging and cancer: Impairment of DNA repair and mitochondrial function of host cells

    Strickertsson, J. A. B., Desler, Claus & Rasmussen, Lene Juel, Aug 2014, In: Experimental Gerontology. 56, p. 164-174 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Impact of oral contraceptive use and menstrual phases on patellar tendon morphology, biochemical composition and biomechanical properties in female athletes

    Hansen, M. D., Couppé, Christian, Hansen, C., Skovgaard, D., Kovanen, V., Larsen, J. O., Aagaard, P., Magnusson, Stig Peter & Kjær, Michael, 21 Feb 2013, In: Journal of Applied Physiology. 114, p. 998-1008 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Impaired dynamics and function of mitochondria caused by mtDNA toxicity leads to heart failure

    Lauritzen, K. H., Kleppa, L., Aronsen, J. M., Eide, L., Carlsen, H., Haugen, O. P., Sjaastad, I., Klungland, A., Rasmussen, Lene Juel, Attramadal, H., Storm-Mathisen, J. & Bergersen, L. H., 1 Aug 2015, In: American Journal of Physiology: Heart and Circulatory Physiology. 309, 3, p. H434-H449 16 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Improved Functional Performance in Geriatric Patients During Hospital Stay

    Karlsen, Anders, Loeb, M. R., Andersen, K. B., Joergensen, K. J., Scheel, F. U., Turtumoeygard, I. F., Perez, A. L. R., Kjær, Michael & Beyer, N., 2017, In: American Journal of Physical Medicine and Rehabilitation. 96, 5, p. e78-e84

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Improved skeletal muscle mass and strength after heavy strength training in very old individuals

    Bechshøft, R. L., Malmgaard-Clausen, N. M., Gliese, B., Beyer, N., Mackey, Abigail, Andersen, J. L., Kjær, Michael & Holm, L., 2017, In: Experimental Gerontology. 92, p. 96-105 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    In Silico screening for functional candidates amongst hypothetical proteins

    Desler, Claus, Suravajhala, P., Sanderhoff, M., Rasmussen, M. & Rasmussen, Lene Juel, 2009, In: BMC Bioinformatics. 10, p. 289

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    In acutely admitted geriatric patients, offering increased physical activity during hospitalization decreases length of stay and can improve mobility

    Oestergaard, A. S., Mathiesen, M. H., Karlsen, Anders, Turtumoeygaard, I. F., Vahlgren, J., Kjær, Michael & Beyer, N., 2018, In: Translational Sports Medicine. 1, 1, p. 46-53

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    In hip osteoarthritis, Nordic Walking is superior to strength training and home based exercise for improving function

    Bieler, T., Siersma, Volkert Dirk, Magnusson, Stig Peter, Kjær, Michael, Christensen, H. E. & Beyer, N., Aug 2017, In: Scandinavian Journal of Medicine & Science in Sports. 27, 8, p. 873–886 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    In response: Gamma oscillations or spikes?

    Benedek, Krisztina & Lauritzen, Martin, Sep 2016, In: Epilepsia. 57, 9, p. 1524–1525 2 p.

    Research output: Contribution to journal › Comment/debate › Research › peer-review

  19. Published

    In vitro tendon tissue development from human fibroblasts demonstrates collagen fibril diameter growth associated with a rise in mechanical strength

    Herchenhan, A., Bayer, M. L., Svensson, R. B., Magnusson, Stig Peter & Kjær, Michael, 2013, In: Developmental Dynamics. 242, 1, p. 2-8 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Increase in tendon protein synthesis in response to insulin-like growth factor-I is preserved in elderly men

    Nielsen, R. H., Holm, L., Malmgaard-Clausen, N. M., Reitelseder, S., Heinemeier, K. M. & Kjær, Michael, 1 Jan 2014, In: Journal of Applied Physiology. 116, 1, p. 42-6 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Increased 20-HETE synthesis explains reduced cerebral blood flow but not impaired neurovascular coupling after cortical spreading depression in rat cerebral cortex: 20-HETE synthesis explains reduced CBF after CSD

    Fordsmann, J. C., ko, R., Choi, H. B., Thomsen, Kirsten Joan, Witgen, B. M., Mathiesen, C., Lønstrup, M., Hansen, H. P., MacVicar, B. A. & Lauritzen, Martin, Feb 2013, In: Journal of Neuroscience. p. 2562-2570 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Increased Rrm2 gene dosage reduces fragile site breakage and prolongs survival of ATR mutant mice

    Lopez-Contreras, Andres, Specks, J., Barlow, J. H., Ambrogio, C., Desler, Claus, Vikingsson, S., Rodrigo-Perez, S., Green, H., Rasmussen, Lene Juel, Murga, M., Nussenzweig, A. & Fernandez-Capetillo, O., 1 Apr 2015, In: Genes & Development. 29, 7, p. 690-5 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Increased deoxythymidine triphosphate levels is a feature of relative cognitive decline

    Desler, Claus, Frederiksen, J. H., Olsen, M. N. A., Maynard, S., Keijzers, G., Fagerlund, Birgitte, Mortensen, Erik Lykke, Osler, Merete, Lauritzen, Martin, Bohr, Vilhelm & Rasmussen, Lene Juel, Nov 2015, In: Mitochondrion. 25, p. 34-7 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Inducible Degradation of the Human SMC5/6 Complex Reveals an Essential Role Only during Interphase

    Venegas, A. B., Natsume, T., Kanemaki, M. & Hickson, Ian David, 2020, In: Cell Reports. 31, 3, 20 p., 107533.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Inducing and Detecting Mitotic DNA Synthesis at Difficult-to-Replicate Loci

    Garribba, L., Wu, Wei, Özer, Ö., Bhowmick, Rahul, Hickson, Ian David & Liu, Ying, 2018, Methods in Enzymology: Mechanisms of DNA Recombination and Genome Rearrangements: Intersection between Homologous Recombination, DNA Replication and DNA Repair. Spies, M. & Malkova, A. (eds.). Elsevier, Vol. 601. p. 45-58 14 p. (Methods in Enzymology; No. 601).

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  26. Published

    Inflammation relates to resistance training-induced hypertrophy in elderly patients

    Norheim, K. L., Cullum, C. K., Andersen, J. L., Kjær, Michael & Karlsen, Anders, Jun 2017, In: Medicine and Science in Sports and Exercise. 49, 6, p. 1079-1085 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    Influence of Nodal signalling on pluripotency factor expression, tumour cell proliferation and cisplatin-sensitivity in testicular germ cell tumours

    Harpelunde Poulsen, K., Nielsen, J. E., Grønkær Toft, B., Joensen, Ulla Nordström, Rasmussen, Lene Juel, Blomberg Jensen, M., Mitchell, R. T., Juul, Anders, Rajpert-De Meyts, E. & Jørgensen, Anders, 2020, In: BMC Cancer. 20, 1, 14 p., 349.

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    Influence of Oral Contraceptive Use on Adaptations to Resistance Training

    Dalgaard, L. B., Dalgas, U., Andersen, J. L., Rossen, N. B., Moller, A. B., Stodkilde-Jorgensen, H., Jorgensen, J. O., Kovanen, V., Couppe, C., Langberg, Henning, Kjær, Michael & Hansen, M., Jul 2019, In: Frontiers in Physiology. 10, 14 p., 824.

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    Influence of Sex and Estrogen on Musculotendinous Protein Turnover at Rest and After Exercise

    Hansen, M. & Kjær, Michael, 2014, In: Exercise and Sport Sciences Reviews. 42, 4, p. 183–192 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    Influence of ornithine decarboxylase antizymes and antizyme inhibitors on agmatine uptake by mammalian cells

    Ramos-Molina, B., Lopez-Contreras, Andres, Lambertos, A., Dardonville, C., Cremades, A. & Peñafiel, R., 2015, In: Amino Acids. 47, 5, p. 1025-34 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Published

    Influence of the integrin alpha-1 subunit and its relationship with high-fat diet upon extracellular matrix synthesis in skeletal muscle and tendon

    Bayer, M. L., Svensson, R. B., Schjerling, P., Williams, A. S., Wasserman, D. H. & Kjær, Michael, 2020, In: Cell and Tissue Research. 381, 1, p. 177-187

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. Published

    Initial brain aging: heterogeneity of mitochondrial size is associated with decline in complex I-linked respiration in cortex and hippocampus

    Thomsen, Kirsten Joan, Yokota, T., Hasan-Olive, M. M., Sherazi, N., Fakouri, N. B., Desler, Claus, Regnell, C. E., Larsen, S., Rasmussen, Lene Juel, Dela, Flemming, Bergersen, L. H. & Lauritzen, Martin, 2018, In: Neurobiology of Aging. 61, p. 215-224 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. Published

    Instability in NAD+ metabolism leads to impaired cardiac mitochondrial function and communication

    Lauritzen, K. H., Olsen, M. B., Ahmed, M. S., Yang, K., Rinholm, J. E., Bergersen, L. H., Esbensen, Q. Y., Sverkeli, L. J., Ziegler, M., Attramadal, H., Halvorsen, B., Aukrust, P. & Yndestad, A., 2021, In: eLife. 10, 23 p., 59828.

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Published

    Insulin-like growth factor I enhances collagen synthesis in engineered human tendon tissue

    Herchenhan, A., Bayer, M. L., Eliasson, P., Magnusson, Stig Peter & Kjær, Michael, Feb 2015, In: Growth Hormone & I G F Research. 25, 1, p. 13-19 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. Published

    Integrated Measurements of Electrical Activity, Oxygen Tension, Blood Flow, and Ca2+ -Signaling in Rodents In Vivo

    Mathiesen, C., Thomsen, K. & Lauritzen, Martin, 2014, Brain Energy Metabolism. Hirrlinger, J. & Waagepetersen, H. S. (eds.). p. 243-264 22 p.

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Education › peer-review

  36. Published

    Integrated measurements of electrical activity, Oxygen tension, Blood flow, And Ca2+-Signaling in rodents in vivo

    Mathiesen, C., Thomsen, Kirsten Joan & Lauritzen, Martin, 1 Jan 2014, Brain Energy Metabolism. Vol. 90. p. 243-264 22 p. (Neuromethods).

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  37. Published

    Integrated method for quantitative morphometry and oxygen transport modeling in striated muscle

    Al-Shammari, A. A., Kissane, R. W. P., Holbek, S., Mackey, Abigail, Andersen, T. R., Gaffney, E. A., Kjær, Michael & Egginton, S., 2019, In: Journal of Applied Physiology. 126, 3, p. 544-557 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. Published

    Interaction between RECQL4 and OGG1 promotes repair of oxidative base lesion 8-oxoG and is regulated by SIRT1 deacetylase

    Duan, S., Han, X., Akbari, M., Croteau, D. L., Rasmussen, Lene Juel & Bohr, Vilhelm, 2020, In: Nucleic Acids Research. 48, 12, p. 6530–6546

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. Published

    Interaction between the helicases genetically linked to Fanconi anemia group J and Bloom's syndrome

    Suhasini, A. N., Rawtani, N. A., Wu, Y., Sommers, J. A., Sharma, S., Mosedale, G., North, P. S., Cantor, S. B., Hickson, Ian David & Brosh, R. M., 16 Feb 2011, In: E M B O Journal. 30, 4, p. 692-705 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  40. Published

    Interaction of RECQ4 and MCM10 is important for efficient DNA replication origin firing in human cells

    Kliszczak, M., Sedlackova, H., Pitchai, G. P., Streicher, W. W., Krejci, L. & Hickson, Ian David, 1 Dec 2015, In: OncoTarget. 6, 38, p. 40464-79 16 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. Published

    Interneuron Deficit Associates Attenuated Network Synchronization to Mismatch of Energy Supply and Demand in Aging Mouse Brains

    Jessen, S. B., Mathiesen, C., Lind, Barbara Lykke & Lauritzen, Martin, 2017, In: Cerebral Cortex. 27, 1, p. 646-659

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. Published

    Interventions for age-related diseases: Shifting the paradigm

    Figueira, I., Fernandes, A., Mladenovic Djordjevic, A., Lopez-Contreras, Andres, Henriques, C. M., Selman, C., Ferreiro, E., Gonos, E. S., Trejo, J. L., Misra, J., Rasmussen, Lene Juel, Xapelli, S., Ellam, T. & Bellantuono, I., Dec 2016, In: Mechanisms of Ageing and Development. 160, p. 69-92 24 p.

    Research output: Contribution to journal › Review › Research › peer-review

  43. Published

    Introducing the hypothome: a way to integrate predicted proteins in interactomes

    Desler, Claus, Zambach, S., Suravajhala, P. & Rasmussen, Lene Juel, 2014, In: International Journal of Bioinformatics Research and Applications. 10, 6, p. 647-52 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Published

    Involvement of the DNA mismatch repair system in cisplatin sensitivity of testicular germ cell tumours

    Rudolph, C., Melau, C., Nielsen, J. E., Jensen, K. V., Liu, D., Pena-Diaz, J., Meyts, E. R., Rasmussen, Lene Juel & Jorgensen, A., 2017, In: Cellular Oncology. 40, 4, p. 341-355

    Research output: Contribution to journal › Journal article › Research › peer-review

  45. Published

    Is There a Link between Mitochondrial Reserve Respiratory Capacity and Aging?

    Hansen, T. L., Rasmussen, Lene Juel, Desler, Claus, Frederiksen, J. B., Espersen, M. L. M. & Singh, K. K., 2012, In: Journal of Aging Research. 2012, p. 192503 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  46. Published

    Is it all in the baseline? Trajectories of chair stand performance over 4 years and their association with grey matter structure in older adults

    Demnitz, N., Gates, A. T., Mortensen, Erik Lykke, Garde, Ellen, Wimmelmann, Cathrine Lawaetz, Siebner, Hartwig Roman, Kjær, Michael & Boraxbekk, CJ, 2023, In: Human Brain Mapping. 44, 11, p. 4299-4309 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. Published

    Is lactate a volume transmitter of metabolic states of the brain?

    Bergersen, L. H. & Gjedde, Albert, 19 Jun 2012, In: Frontiers in Neuroenergetics. 4, Article 5, p. 1-6 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  48. Published

    Isometric abdominal wall muscle strength assessment in individuals with incisional hernia: a prospective reliability study

    Jensen, K. K., Kjær, Michael & Jørgensen, Lars Nannestad, Dec 2016, In: Hernia. 20, 6, p. 831-837

    Research output: Contribution to journal › Journal article › Research › peer-review

  49. Published

    Key Components of Human Myofibre Denervation and Neuromuscular Junction Stability are Modulated by Age and Exercise

    Søndenbroe, C., Bechshøft, C. J. L., Heisterberg, M. F., Jensen, S. M., Bomme, E., Schjerling, Peter, Karlsen, Anders, Kjær, Michael, Andersen, J. L. & Mackey, Abigail, 2020, In: Cells. 9, 4, 893.

    Research output: Contribution to journal › Journal article › Research › peer-review

  50. Published

    Knotty Problems during Mitosis: Mechanistic Insight into the Processing of Ultrafine DNA Bridges in Anaphase

    Sarlós, K., Biebricher, A., Petermann, E. J. G., Wuite, G. J. L. & Hickson, Ian David, 2017, In: Cold Spring Harbor Laboratory. Symposia on Quantitative Biology. 82, p. 187-195

    Research output: Contribution to journal › Journal article › Research › peer-review

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