Damage and Repair

  1. Published

    Fibril morphology and tendon mechanical properties in patellar tendinopathy: effects of heavy slow resistance training

    Kongsgaard, M., Qvortrup, Klaus, Larsen, J. O., Aagaard, P., Doessing, S., Hansen, P., Kjær, Michael, Magnusson, Stig Peter, Kongsgaard, M., Qvortrup, K., Grambo Larsen, J., Aagaard, P., Doessing, S., Hansen, P., Kjær, Michael & Magnusson, Stig Peter, 1 Apr 2010, In: American Journal of Sports Medicine. 38, 4, p. 749-56 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    Folate stress induces SLX1- and RAD51-dependent mitotic DNA synthesis at the fragile X locus in human cells

    Garribba, L., Bjerregaard, Victoria Alexandra, Gonçalves Dinis, M. M., Özer, Ö., Wu, Wei, Sakellariou, D., Pena-Diaz, J., Hickson, Ian David & Liu, Ying, 2020, In: Proceedings of the National Academy of Sciences of the United States of America. 117, 28, p. 16527-16536 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    From mechanical loading to collagen synthesis, structural changes and function in human tendon

    Kjær, Michael, Langberg, Henning, Heinemeier, K., Bayer, M. L., Hansen, M., Holm, L., Doessing, S., Kongsgaard, M., Krogsgaard, Michael R. & Magnusson, Stig Peter, 2009, In: Scandinavian Journal of Medicine & Science in Sports Online. 19, 4, p. 500-10 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    From powerhouse to perpetrator—mitochondria in health and disease

    Fakouri, N. B., Hansen, T. L., Desler, Claus, Anugula, Sharath & Rasmussen, Lene Juel, 2019, In: Biology. 8, 2, 15 p., 35.

    Research output: Contribution to journalReviewResearchpeer-review

  5. Published

    Functional adaptation of tendon and skeletal muscle to resistance training in three patients with genetically verified classic Ehlers Danlos Syndrome

    Møller, M. B., Kjær, Michael, Svensson, R. B., Andersen, J. L., Magnusson, Stig Peter & Nielsen, R. H., 2014, In: M.L.T.J. Muscles, Ligaments and Tendons Journal. 4, 3, p. 315-323 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Functional characterization of MLH1 missense variants identified in Lynch Syndrome patients

    Andersen, S. D., Liberti, S. E., Lützen, A., Drost, M., Bernstein, I., Nilbert, Mef Christina, Dominguez, M., Nyström, M., Hansen, Thomas van Overeem, Christoffersen, J. W., Jäger, A. C., de Wind, N., Nielsen, Finn Cilius, Tørring, P. M. & Rasmussen, Lene Juel, Dec 2012, In: Human Mutation. 33, 12, p. 1647-1655 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Functional examination of MLH1, MSH2, and MSH6 intronic mutations identified in Danish colorectal cancer patients

    Petersen, S. M., Dandanell, M., Rasmussen, Lene Juel, Gerdes, Anne-Marie Axø, Krogh, L. N., Bernstein, I., Okkels, H., Wikman, F., Nielsen, Finn Cilius & Hansen, Thomas van Overeem, 2013, In: BMC Medical Genetics. 14, p. 103

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Functional implications of the p.Cys680Arg mutation in the MLH1 mismatch repair protein

    Dominguez-Valentin, M., Drost, M., Therkildsen, C., Rambech, E., Ehrencrona, H., Angleys, M., Lau Hansen, T., de Wind, N., Nilbert, Mef Christina & Rasmussen, Lene Juel, Jul 2014, In: Molecular Genetics & Genomic Medicine. 2, 4, p. 352-355 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    GABAA Receptor-Mediated Bidirectional Control of Synaptic Activity, Intracellular Ca2+, Cerebral Blood Flow, and Oxygen Consumption in Mouse Somatosensory Cortex In Vivo

    Jessen, S. B., Brazhe, A., Lind, Barbara Lykke, Mathiesen, C., Thomsen, K., Jensen, K. & Lauritzen, Martin, 2015, In: Cerebral Cortex. 25, 9, p. 2594-2609 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    GH and IGF1 levels are positively associated with musculotendinous collagen expression: experiments in acromegalic and GH deficiency patients

    Doessing, S., Holm, L., Heinemeier, K. M., Feldt-Rasmussen, Ulla, Schjerling, Peter, Qvortrup, Klaus, Larsen, J. O., Nielsen, R. H., Flyvbjerg, A. & Kjær, Michael, Dec 2010, In: European Journal of Endocrinology. 163, 6, p. 853-62 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    GH/IGF-I axis and matrix adaptation of the musculotendinous tissue to exercise in humans

    Heinemeier, K. M., Mackey, Abigail, Doessing, S., Hansen, M., Bayer, M. L., Nielsen, R. H., Herchenhan, A., Malmgaard-Clausen, N. M. & Kjær, Michael, Aug 2012, In: Scandinavian Journal of Medicine & Science in Sports. 22, 4, p. e1-7

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Galectin-7 reprograms skin carcinogenesis by fostering innate immune evasive programs

    Pinto, N. A., Abba, M. C., Laporte, L., Pérez Sáez, J. M., Blidner, A. G., Torres, N. I., Morales, R. M., Gatto, S. G., Bach, C. A., Veigas, F., García Rivello, H. J., Song, P., Frederiksen, J. H., Rasmussen, Lene Juel, Poirier, F., Croci, D. O., Sundblad, V., Rabinovich, G. A. & Cerliani, J. P., 2023, In: Cell Death and Differentiation. 30, p. pages906–921

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Genetic insights into biological mechanisms governing human ovarian ageing

    Ruth, K. S., Day, F. R., Hussain, J., Martinez-Marchal, A., Aiken, C. E., Azad, A., Thompson, D. J., Knoblochova, L., Abe, H., Tarry-Adkins, J. L., Gonzalez, J. M., Fontanillas, P., Claringbould, A., Bakker, O. B., Sulem, P., Walters, R. G., Terao, C., Turon, S., Horikoshi, M., Lin, K. & 36 others, Onland-Moret, N. C., Sankar, A., Hertz, Emil Peter Thrane, Timshel, P. N., Shukla, V., Borup, R., Olsen, K. W., Aguilera, P., Ferrer-Roda, M., Huang, Y., Stankovic, S., Timmers, P. R. H. J., Ahearn, T. U., Alizadeh, B. Z., Naderi, E., Andrulis, I. L., Arnold, A. M., Aronson, K. J., Augustinsson, A., Bojesen, Stig Egil, Hoffding, M. K., Shrikhande, A., Pers, Tune H, Grøndahl, M. L., tcg964, tcg964, Lopez-Contreras, Andres, Daniel, J. A., Hoffmann, Eva, Biobank-based Integrative Omics St, B. I. O. S., eQTLGen Consortium, E. C., BioBank Japan Project, B. J. P., China Kadoorie Biobank Collaborati, C. K. B. C., kConFab Investigators, K. I., LifeLines Cohort Study, L. C. S., InterAct Consortium, I. C. & 23 Me Res Team, 2. M. R. T., 2021, In: Nature. 596, p. 393-397

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Genetic screens to identify pathogenic gene variants in the common cancer predisposition Lynch syndrome

    Drost, M., Lützen, A., van Hees, S., Ferreira, D., Calléja, F., Zonneveld, J. B. M., Nielsen, Finn Cilius, Rasmussen, Lene Juel & de Wind, N., 2013, In: Proceedings of the National Academy of Sciences of the United States of America. 110, 23, p. 9403-9408 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Genetic screens to identify pathogenic gene variants in the common cancer predisposition Lynch syndrome

    Drost, M., Lützen, A., van Hees, S., Ferreira, D., Calléja, F., Zonneveld, J. B. M., Nielsen, Finn Cilius, Rasmussen, Lene Juel & de Wind, N., 4 Jun 2013, In: Proceedings of the National Academy of Science of the United States of America. 110, 23, p. 9403-8 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Genome-wide screens for expressed hypothetical proteins

    Desler, Claus, Durhuus, J. A. & Rasmussen, Lene Juel, 2012, In: Methods in molecular biology (Clifton, N.J.). 815, p. 25-38 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Genomic and functional integrity of the hematopoietic system requires tolerance of oxidative DNA lesions

    Martín-Pardillos, A., Tsaalbi-Shtylik, A., Chen, S., Lazare, S., Van Os, R. P., Dethmers-Ausema, A., Fakouri, N. B., Bosshard, M., Aprigliano, R., Van Loon, B., Salvatori, D. C. F., Hashimoto, K., Van Der Spek, C. D., Moriya, M., Rasmussen, Lene Juel, De Haan, G., Raaijmakers, M. H. G. P. & De Wind, N., 2017, In: Blood. 130, 13, p. 1523-1534 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Genomic instability and aging

    Li, Zhiquan, Anugula, Sharath & Rasmussen, Lene Juel, 2022, Aging: From Fundamental Biology to Societal Impact. Oliveira, P. J. & Malva, J. O. (eds.). Academic Press, p. 275-295 21 p.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  19. Published

    Glia-Neuron Interactions in the Retina Can Be Studied in Cocultures of Muller Cells and Retinal Ganglion Cells

    Jensen, Dorte Skytt, Toft-Kehler, A. K., Braendstrup, C. T., Cejvanovic, S., Gurubaran, I. S., Bergersen, L. H. & Kolko, Miriam, 2016, In: Journal of Biomedicine and Biotechnology. 2016, 11 p., 1087647.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Glucosamine but not iboprofen alters cartilage turnover in osteoarthritis patients in response to physical training

    Petersen, S. G., Saxne, T., Heinegard, D., Hansen, M., Holm, L., Koskinen, S., Stordal, C., Christensen, H., Aagaard, P. & Kjær, Michael, 2010, In: Osteoarthritis and Cartilage. 18, 1, p. 34-40

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Glutamate-system defects behind psychiatric manifestations in a familial hemiplegic migraine type 2 disease-mutation mouse model

    Bøttger, P., Glerup, S., Gesslein, B., Illarionova, N. B., Isaksen, T. J., Heuck, A., Clausen, B. H., Füchtbauer, E., Gramsbergen, J. B., Gunnarson, E., Aperia, A., Lauritzen, Martin, Lambertsen, K. L., Nissen, P. & Lykke-Hartmann, K., 25 Feb 2016, In: Scientific Reports. 6, 21 p., 22047.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Glutaraldehyde Cross-Linking of TendonMechanical Effects at the Level of the Tendon Fascicle and Fibril

    Hansen, P., Svensson, R. B., Aagaard, P., Trappe, T., Haraldsson, B. T., Kjær, Michael, Magnusson, P. & Hassenkam, Tue, 2009, In: Connective Tissue Research. 50, 4, p. 211-222 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Glutaraldehyde cross-linking of tendon mechanical effects at the level of the tendon fascicle and fibril

    Hansen, P., Hassenkam, Tue, Svensson, R. B., Aagaard, P., Trappe, T., Haraldsson, B. T., Kjær, Michael & Magnusson, P., 2009, In: Connective Tissue Research. 50, 4, p. 211-22 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Growth Hormone Receptor Antagonist Treatment Reduces Exercise Performance in Young Males

    Goto, K., Doessing, S., Nielsen, R. H., Flyvbjerg, A. & Kjær, Michael, 2009, In: Journal of Clinical Endocrinology and Metabolism. 94, 9, p. 3265-3272 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Growth hormone stimulates the collagen synthesis in human tendon and skeletal muscle without affecting myofibrillar protein synthesis

    Doessing, S., Heinemeier, K. M., Holm, L., Mackey, Abigail, Schjerling, Peter, Rennie, M., Petersen, K. S., Reitelseder, S., Kappelgaard, A., Rasmussen, M. H., Flyvbjerg, A. & Kjær, Michael, 15 Jan 2010, In: Journal of Physiology. 588, Pt 2, p. 341-51 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    H4K20me0 marks post-replicative chromatin and recruits the TONSL–MMS22L DNA repair complex

    Saredi, G., Huang, H., Hammond, Colin, Alabert, C., Bekker-Jensen, Simon Holst, Forne, I., Reveron-Gomez, Nazaret, Foster, B. M., Mlejnkova, L., Bartke, T., Cejka, P., Mailand, Niels, Imhof, A., Patel, D. J. & Groth, Anja, 30 Jun 2016, In: Nature. 534, 7609, p. 714-8 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Habitual side-specific loading leads to structural, mechanical, and compositional changes in the patellar tendon of young and senior lifelong male athletes

    Couppé, Christian, Svensson, R. B., Skovlund, S. V., Jensen, Jacob Kildevang, Eriksen, C. S., Malmgaard-Clausen, N. M., Nybing, J. D., Kjær, Michael & Magnusson, Stig Peter, 2021, In: Journal of Applied Physiology. 131, 4, p. 1187-1199

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Handgrip strength shows no improvements in geriatric patients with persistent inflammation during hospitalization

    Norheim, K. L., Bautmans, I. & Kjær, Michael, 1 Dec 2017, In: Experimental Gerontology. 99, p. 115-119 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Heavy Slow Resistance Versus Eccentric Training as Treatment for Achilles Tendinopathy: A Randomized Controlled Trial

    Beyer, R., Kongsgaard, M., Hougs Kjær, B., Øhlenschlæger, Tommy Frisgaard, Kjær, Michael & Magnusson, Stig Peter, Jul 2015, In: American Journal of Sports Medicine. 43, 7, p. 1704-11 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Helicobacter pylori infection generates genetic instability in gastric cells

    Machado, A. M. D., Figueiredo, C., Seruca, R. & Rasmussen, Lene Juel, 2010, In: BBA General Subjects. 1806, 1, p. 58-65 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    Helicobacter pylori infection induces genetic instability of nuclear and mitochondrial DNA in gastric cells

    Machado, A. M. D., Figueiredo, C., Touati, E., Máximo, V., Sousa, S., Michel, V., Carneiro, F., Nielsen, Finn Cilius, Seruca, R. & Rasmussen, Lene Juel, 2009, In: Clinical Cancer Research. 15, 9, p. 2995-3002 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    Heterogeneity of ductular reactions in adult rat and human liver revealed by novel expression of deleted in malignant brain tumor

    Bisgaard, Hanne Cathrine, Holmskov, U., Santoni Rugiu, Eric, Nagy, P., Nielsen, O., Ott, P., Hage, E., Dalhoff, Kim, Rasmussen, Lene Juel & Tygstrup, N., 2002, In: American Journal of Pathology. 161, 4, p. 1187-1198 12 p., 64395.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    Heterogeneity of ductular reactions in adult rat and human liver revealed by novel expression of deleted in malignant brain tumor

    Bisgaard, Hanne Cathrine, Holmskov, U., Santoni Rugiu, Eric, Nagy, P., Nielsen, O., Ott, P., Hage, E., Dalhoff, Kim, Rasmussen, Lene Juel & Tygstrup, N., 2002, In: American Journal of Pathology. 161, 4, p. 1187-1198 12 p., 64395.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    Heterotopic Ossification after an Achilles Tendon Rupture Cannot Be Prevented by Early Functional Rehabilitation: A Cohort Study

    Magnusson, Stig Peter, Agergaard, A. S., Couppé, Christian, Svensson, R. B., Warming, S., Krogsgaard, Michael R., Kjær, Michael & Eliasson, P., 2020, In: Clinical Orthopaedics and Related Research. 478, 5, p. 1101-1108 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    High Intensity Interval Training Ameliorates Mitochondrial Dysfunction in the Left Ventricle of Mice with Type 2 Diabetes

    Baekkerud, F. H., Salerno, S., Ceriotti, P., Morland, C., Storm-Mathisen, J., Bergersen, L. H., Hoydal, M. A., Catalucci, D. & Stolen, T. O., 2019, In: Cardiovascular Toxicology. 19, 5, p. 422-431 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    High-confidence cancer patient stratification through multiomics investigation of DNA repair disorders

    Mkrtchyan, Garik, Veviorskiy, A., Izumchenko, E., Shneyderman, A., Pun, F. W., Ozerov, I. V., Aliper, A., Zhavoronkov, A. & Scheibye-Knudsen, Morten, 2022, In: Cell Death and Disease. 13, 11, 999.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    High-resolution mapping of mitotic DNA synthesis regions and common fragile sites in the human genome through direct sequencing

    Macheret, M., Bhowmick, Rahul, Sobkowiak, K., Padayachy, L., Mailler, J., Hickson, Ian David & Halazonetis, T. D., 2020, In: Cell Research. 30, p. 997–1008

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    Histology and Function of the Rectus Abdominis Muscle in Patients With Incisional Hernia

    Jensen, K. K., Oma, E., Kjær, Michael, Jørgensen, Lars Nannestad & Andersen, J. L., 2020, In: Journal of Surgical Research. 253, p. 245-251 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Histone H1 couples initiation and amplification of ubiquitin signalling after DNA damage

    Thorslund, T., Ripplinger, A., Hoffmann, Saskia, Wild, T., Uckelmann, M., Villumsen, B., Narita, Takeo, Sixma, T. K., Choudhary, Chunaram, Bekker-Jensen, Simon Holst & Mailand, Niels, 19 Nov 2015, In: Nature. 527, 7578, p. 389-93 5 p.

    Research output: Contribution to journalLetterResearchpeer-review

  40. Published

    Histone displacement during nucleotide excision repair

    Dinant, C., Bartek, J. & Bekker-Jensen, Simon Holst, 17 Oct 2012, In: International Journal of Molecular Sciences (Online). 13, 10, p. 13322-13337 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    Histone malonylation is regulated by SIRT5 and KAT2A

    Zhang, R., Bons, J., Scheidemantle, G., Liu, X., Bielska, O., Carrico, C., Rose, J., Heckenbach, Indra John, Scheibye-Knudsen, Morten, Schilling, B. & Verdin, E., 2023, In: iScience. 26, 3, 106193.

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    Holliday junction-containing DNA structures persist in cells lacking Sgs1 or Top3 following exposure to DNA damage

    Mankouri, H. W., Ashton, T. M. & Hickson, Ian David, 22 Mar 2011, In: Proceedings of the National Academy of Sciences USA (PNAS). 108, 12, p. 4944-9 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    How Do We Explore Heterogeneity in Turnover of Musculoskeletal Proteins?

    Agergaard, J. & Kjær, Michael, 2021, In: Function. 2, 4, 2 p., 034.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    How unfinished business from S-phase affects mitosis and beyond

    Mankouri, H. W., Huttner, D. & Hickson, Ian David, 16 Oct 2013, In: EMBO Journal. 32, 20, p. 2661-71 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    Human Achilles tendon glycation and function in diabetes

    Couppé, Christian, Svensson, R. B., Madsen, M. K., Kovanen, V., Grosset, J., Snorgaard, O., Bencke, J., Larsen, J. O., Bandholm, Thomas Quaade, Christensen, T. M., Boesen, A., Helmark, I. C., Aagaard, P., Kjær, Michael & Magnusson, Stig Peter, Jan 2016, In: Journal of Applied Physiology. 120, 2, p. 130-137 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    Human DNA polymerase delta double-mutant D316A;E318A interferes with DNA mismatch repair in vitro

    Liu, D., Frederiksen, J. H., Liberti, S. E., Lützen, Anne Hoff Kjeldsen, Keijzers, G., Pena-Diaz, J. & Rasmussen, Lene Juel, 19 Sep 2017, In: Nucleic Acids Research. 45, 16, p. 9427-9440 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    Human RNF169 is a negative regulator of the ubiquitin-dependent response to DNA double-strand breaks

    Poulsen, M., Lukas, C., Lukas, J., Bekker-Jensen, Simon Holst & Mailand, Niels, 2012, In: Journal of Cell Biology. 197, 2, p. 189-99 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    Human cancer cells utilize mitotic DNA synthesis to resist replication stress at telomeres regardless of their telomere maintenance mechanism

    Özer, Ö., Bhowmick, Rahul, Liu, Ying & Hickson, Ian David, 2018, In: OncoTarget. 9, 22, p. 15836-15846 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    Human derived tendon cells contribute to myotube formation in vitro

    Tsuchiya, Y., Bayer, M. L., Schjerling, Peter, Soendenbroe, C. & Kjær, Michael, 2022, In: Experimental Cell Research. 417, 1, 113164.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    Human exonuclease 1 (EXO1) activity characterization and its function on FLAP structures

    Keijzers, G., Bohr, Vilhelm & Rasmussen, Lene Juel, 2015, In: Bioscience Reports. 35, 3, 13 p., e00206.

    Research output: Contribution to journalJournal articleResearchpeer-review

  51. Published

    Human exonuclease 1 (EXO1) regulatory functions in DNA replication with putative roles in cancer

    Keijzers, G., Bakula, Daniela Janina, Petr, Michael Angelo, Madsen, N. G. K., Teklu, Amanuel Abraha, Mkrtchyan, Garik, Osborne, Brenna & Scheibye-Knudsen, Morten, 2019, In: International Journal of Molecular Sciences . 20, 1, 15 p., 74.

    Research output: Contribution to journalReviewResearchpeer-review

  52. Published

    Human skeletal muscle fibroblasts stimulate in vitro myogenesis and in vivo muscle regeneration

    Mackey, Abigail, Magnan, M., Chazaud, B. & Kjær, Michael, 2017, In: The Journal of Physiology. 595, 15, p. 5115-5127 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  53. Published

    Human topoisomerase IIIalpha is a single-stranded DNA decatenase that is stimulated by BLM and RMI1

    Yang, J., Bachrati, C. Z., Ou, J., Hickson, Ian David & Brown, G. W., 2010, In: Journal of Biological Chemistry. 285, 28, p. 21426-36 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  54. Published

    Hyposalivation and Poor Dental Health Status Are Potential Correlates of Age-Related Cognitive Decline in Late Midlife in Danish Men

    Sørensen, Christiane Elisabeth, Hansen, N. L., Mortensen, Erik Lykke, Lauritzen, Martin, Osler, Merete & Pedersen, Anne Marie Lynge, 2018, In: Frontiers in Aging Neuroscience. 10, p. 1-7 7 p., 10.

    Research output: Contribution to journalJournal articleResearchpeer-review

  55. Published

    ICLs: a chicken without an egg

    Bekker-Jensen, Simon Holst & Mailand, Niels, 2012, In: Nature Reviews. Molecular Cell Biology. 13, 6, p. 342

    Research output: Contribution to journalReviewResearchpeer-review

  56. Published

    Ibuprofen alters human testicular physiology to produce a state of compensated hypogonadism

    Kristensen, D. M., Desdoits-Lethimonier, C., Mackey, Abigail, Dalgaard, M. D., De Masi, F., Munkbøl, C. H., Styrishave, Bjarne, Antignac, J., Le Bizec, B., Platel, C., Hay-Schmidt, Anders, Jensen, T. K., Lesné, L., Mazaud-Guittot, S., Kristiansen, Karsten, Brunak, Søren, Kjær, Michael, Juul, Anders & Jégou, B., 2018, In: Proceedings of the National Academy of Sciences of the United States of America. 115, 4, p. e715-e724 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  57. Published

    Identification of athletes at future risk of anterior cruciate ligament ruptures by neuromuscular screening

    Zebis, M. K., Andersen, L. L., Bencke, J., Kjær, Michael & Aagaard, P., 2009, In: American Journal of Sports Medicine. 37, 10, p. 1967-73 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  58. Published

    Immobilization Decreases FOXO3a Phosphorylation and Increases Autophagy-Related Gene and Protein Expression in Human Skeletal Muscle

    Møller, A. B., Vendelbo, M. H., Schjerling, Peter, Couppé, Christian, Møller, N., Kjær, Michael, Hansen, M. & Jessen, N., 14 Jun 2019, In: Frontiers in Physiology. 10, 14 p., 736.

    Research output: Contribution to journalJournal articleResearchpeer-review

  59. Published

    Impact of GH administration on athletic performance in healthy young adults: A systematic review and meta-analysis of placebo-controlled trials

    Hermansen, K., Bengtsen, M., Kjær, Michael, Vestergaard, P. & Jørgensen, J. O. L., 2017, In: Growth Hormone & I G F Research. 34, p. 38-44

    Research output: Contribution to journalReviewResearchpeer-review

  60. Published

    Impact of bacterial infections on aging and cancer: Impairment of DNA repair and mitochondrial function of host cells

    Strickertsson, J. A. B., Desler, Claus & Rasmussen, Lene Juel, Aug 2014, In: Experimental Gerontology. 56, p. 164-174 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  61. Published

    Impact of oral contraceptive use and menstrual phases on patellar tendon morphology, biochemical composition and biomechanical properties in female athletes

    Hansen, M. D., Couppé, Christian, Hansen, C., Skovgaard, D., Kovanen, V., Larsen, J. O., Aagaard, P., Magnusson, Stig Peter & Kjær, Michael, 21 Feb 2013, In: Journal of Applied Physiology. 114, p. 998-1008 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  62. Published

    Impaired dynamics and function of mitochondria caused by mtDNA toxicity leads to heart failure

    Lauritzen, K. H., Kleppa, L., Aronsen, J. M., Eide, L., Carlsen, H., Haugen, O. P., Sjaastad, I., Klungland, A., Rasmussen, Lene Juel, Attramadal, H., Storm-Mathisen, J. & Bergersen, L. H., 1 Aug 2015, In: American Journal of Physiology: Heart and Circulatory Physiology. 309, 3, p. H434-H449 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  63. Published

    Improved Functional Performance in Geriatric Patients During Hospital Stay

    Karlsen, Anders, Loeb, M. R., Andersen, K. B., Joergensen, K. J., Scheel, F. U., Turtumoeygard, I. F., Perez, A. L. R., Kjær, Michael & Beyer, N., 2017, In: American Journal of Physical Medicine and Rehabilitation. 96, 5, p. e78-e84

    Research output: Contribution to journalJournal articleResearchpeer-review

  64. Published

    Improved skeletal muscle mass and strength after heavy strength training in very old individuals

    Bechshøft, R. L., Malmgaard-Clausen, N. M., Gliese, B., Beyer, N., Mackey, Abigail, Andersen, J. L., Kjær, Michael & Holm, L., 2017, In: Experimental Gerontology. 92, p. 96-105 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  65. Published

    In Silico screening for functional candidates amongst hypothetical proteins

    Desler, Claus, Suravajhala, P., Sanderhoff, M., Rasmussen, M. & Rasmussen, Lene Juel, 2009, In: BMC Bioinformatics. 10, p. 289

    Research output: Contribution to journalJournal articleResearchpeer-review

  66. Published

    In acutely admitted geriatric patients, offering increased physical activity during hospitalization decreases length of stay and can improve mobility

    Oestergaard, A. S., Mathiesen, M. H., Karlsen, Anders, Turtumoeygaard, I. F., Vahlgren, J., Kjær, Michael & Beyer, N., 2018, In: Translational Sports Medicine. 1, 1, p. 46-53

    Research output: Contribution to journalJournal articleResearchpeer-review

  67. Published

    In hip osteoarthritis, Nordic Walking is superior to strength training and home based exercise for improving function

    Bieler, T., Siersma, Volkert Dirk, Magnusson, Stig Peter, Kjær, Michael, Christensen, H. E. & Beyer, N., Aug 2017, In: Scandinavian Journal of Medicine & Science in Sports. 27, 8, p. 873–886 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  68. Published

    In response: Gamma oscillations or spikes?

    Benedek, Krisztina & Lauritzen, Martin, Sep 2016, In: Epilepsia. 57, 9, p. 1524–1525 2 p.

    Research output: Contribution to journalComment/debateResearchpeer-review

  69. Published

    In vitro tendon tissue development from human fibroblasts demonstrates collagen fibril diameter growth associated with a rise in mechanical strength

    Herchenhan, A., Bayer, M. L., Svensson, R. B., Magnusson, Stig Peter & Kjær, Michael, 2013, In: Developmental Dynamics. 242, 1, p. 2-8 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  70. Published

    Increase in tendon protein synthesis in response to insulin-like growth factor-I is preserved in elderly men

    Nielsen, R. H., Holm, L., Malmgaard-Clausen, N. M., Reitelseder, S., Heinemeier, K. M. & Kjær, Michael, 1 Jan 2014, In: Journal of Applied Physiology. 116, 1, p. 42-6 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  71. Published

    Increased 20-HETE synthesis explains reduced cerebral blood flow but not impaired neurovascular coupling after cortical spreading depression in rat cerebral cortex: 20-HETE synthesis explains reduced CBF after CSD

    Fordsmann, J. C., ko, R., Choi, H. B., Thomsen, Kirsten Joan, Witgen, B. M., Mathiesen, C., Lønstrup, M., Hansen, H. P., MacVicar, B. A. & Lauritzen, Martin, Feb 2013, In: Journal of Neuroscience. p. 2562-2570 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  72. Published

    Increased Rrm2 gene dosage reduces fragile site breakage and prolongs survival of ATR mutant mice

    Lopez-Contreras, Andres, Specks, J., Barlow, J. H., Ambrogio, C., Desler, Claus, Vikingsson, S., Rodrigo-Perez, S., Green, H., Rasmussen, Lene Juel, Murga, M., Nussenzweig, A. & Fernandez-Capetillo, O., 1 Apr 2015, In: Genes & Development. 29, 7, p. 690-5 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  73. Published

    Increased deoxythymidine triphosphate levels is a feature of relative cognitive decline

    Desler, Claus, Frederiksen, J. H., Olsen, M. N. A., Maynard, S., Keijzers, G., Fagerlund, Birgitte, Mortensen, Erik Lykke, Osler, Merete, Lauritzen, Martin, Bohr, Vilhelm & Rasmussen, Lene Juel, Nov 2015, In: Mitochondrion. 25, p. 34-7 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  74. Published

    Inducible Degradation of the Human SMC5/6 Complex Reveals an Essential Role Only during Interphase

    Venegas, A. B., Natsume, T., Kanemaki, M. & Hickson, Ian David, 2020, In: Cell Reports. 31, 3, 20 p., 107533.

    Research output: Contribution to journalJournal articleResearchpeer-review

  75. Published

    Inducing and Detecting Mitotic DNA Synthesis at Difficult-to-Replicate Loci

    Garribba, L., Wu, Wei, Özer, Ö., Bhowmick, Rahul, Hickson, Ian David & Liu, Ying, 2018, Methods in Enzymology: Mechanisms of DNA Recombination and Genome Rearrangements: Intersection between Homologous Recombination, DNA Replication and DNA Repair. Spies, M. & Malkova, A. (eds.). Elsevier, Vol. 601. p. 45-58 14 p. (Methods in Enzymology; No. 601).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  76. Published

    Inflammation relates to resistance training-induced hypertrophy in elderly patients

    Norheim, K. L., Cullum, C. K., Andersen, J. L., Kjær, Michael & Karlsen, Anders, Jun 2017, In: Medicine and Science in Sports and Exercise. 49, 6, p. 1079-1085 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  77. Published

    Influence of Nodal signalling on pluripotency factor expression, tumour cell proliferation and cisplatin-sensitivity in testicular germ cell tumours

    Harpelunde Poulsen, K., Nielsen, J. E., Grønkær Toft, B., Joensen, Ulla Nordström, Rasmussen, Lene Juel, Blomberg Jensen, M., Mitchell, R. T., Juul, Anders, Rajpert-De Meyts, E. & Jørgensen, Anders, 2020, In: BMC Cancer. 20, 1, 14 p., 349.

    Research output: Contribution to journalJournal articleResearchpeer-review

  78. Published

    Influence of Oral Contraceptive Use on Adaptations to Resistance Training

    Dalgaard, L. B., Dalgas, U., Andersen, J. L., Rossen, N. B., Moller, A. B., Stodkilde-Jorgensen, H., Jorgensen, J. O., Kovanen, V., Couppe, C., Langberg, Henning, Kjær, Michael & Hansen, M., Jul 2019, In: Frontiers in Physiology. 10, 14 p., 824.

    Research output: Contribution to journalJournal articleResearchpeer-review

  79. Published

    Influence of Sex and Estrogen on Musculotendinous Protein Turnover at Rest and After Exercise

    Hansen, M. & Kjær, Michael, 2014, In: Exercise and Sport Sciences Reviews. 42, 4, p. 183–192 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  80. Published

    Influence of ornithine decarboxylase antizymes and antizyme inhibitors on agmatine uptake by mammalian cells

    Ramos-Molina, B., Lopez-Contreras, Andres, Lambertos, A., Dardonville, C., Cremades, A. & Peñafiel, R., 2015, In: Amino Acids. 47, 5, p. 1025-34 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  81. Published

    Influence of the integrin alpha-1 subunit and its relationship with high-fat diet upon extracellular matrix synthesis in skeletal muscle and tendon

    Bayer, M. L., Svensson, R. B., Schjerling, P., Williams, A. S., Wasserman, D. H. & Kjær, Michael, 2020, In: Cell and Tissue Research. 381, 1, p. 177-187

    Research output: Contribution to journalJournal articleResearchpeer-review

  82. Published

    Initial brain aging: heterogeneity of mitochondrial size is associated with decline in complex I-linked respiration in cortex and hippocampus

    Thomsen, Kirsten Joan, Yokota, T., Hasan-Olive, M. M., Sherazi, N., Fakouri, N. B., Desler, Claus, Regnell, C. E., Larsen, S., Rasmussen, Lene Juel, Dela, Flemming, Bergersen, L. H. & Lauritzen, Martin, 2018, In: Neurobiology of Aging. 61, p. 215-224 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  83. Published

    Instability in NAD+ metabolism leads to impaired cardiac mitochondrial function and communication

    Lauritzen, K. H., Olsen, M. B., Ahmed, M. S., Yang, K., Rinholm, J. E., Bergersen, L. H., Esbensen, Q. Y., Sverkeli, L. J., Ziegler, M., Attramadal, H., Halvorsen, B., Aukrust, P. & Yndestad, A., 2021, In: eLife. 10, 23 p., 59828.

    Research output: Contribution to journalJournal articleResearchpeer-review

  84. Published

    Insulin-like growth factor I enhances collagen synthesis in engineered human tendon tissue

    Herchenhan, A., Bayer, M. L., Eliasson, P., Magnusson, Stig Peter & Kjær, Michael, Feb 2015, In: Growth Hormone & I G F Research. 25, 1, p. 13-19 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  85. Published

    Integrated Measurements of Electrical Activity, Oxygen Tension, Blood Flow, and Ca2+ -Signaling in Rodents In Vivo

    Mathiesen, C., Thomsen, K. & Lauritzen, Martin, 2014, Brain Energy Metabolism. Hirrlinger, J. & Waagepetersen, H. S. (eds.). p. 243-264 22 p.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterEducationpeer-review

  86. Published

    Integrated measurements of electrical activity, Oxygen tension, Blood flow, And Ca2+-Signaling in rodents in vivo

    Mathiesen, C., Thomsen, Kirsten Joan & Lauritzen, Martin, 1 Jan 2014, Brain Energy Metabolism. Vol. 90. p. 243-264 22 p. (Neuromethods).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  87. Published

    Integrated method for quantitative morphometry and oxygen transport modeling in striated muscle

    Al-Shammari, A. A., Kissane, R. W. P., Holbek, S., Mackey, Abigail, Andersen, T. R., Gaffney, E. A., Kjær, Michael & Egginton, S., 2019, In: Journal of Applied Physiology. 126, 3, p. 544-557 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  88. Published

    Interaction between RECQL4 and OGG1 promotes repair of oxidative base lesion 8-oxoG and is regulated by SIRT1 deacetylase

    Duan, S., Han, X., Akbari, M., Croteau, D. L., Rasmussen, Lene Juel & Bohr, Vilhelm, 2020, In: Nucleic Acids Research. 48, 12, p. 6530–6546

    Research output: Contribution to journalJournal articleResearchpeer-review

  89. Published

    Interaction between the helicases genetically linked to Fanconi anemia group J and Bloom's syndrome

    Suhasini, A. N., Rawtani, N. A., Wu, Y., Sommers, J. A., Sharma, S., Mosedale, G., North, P. S., Cantor, S. B., Hickson, Ian David & Brosh, R. M., 16 Feb 2011, In: E M B O Journal. 30, 4, p. 692-705 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  90. Published

    Interaction of RECQ4 and MCM10 is important for efficient DNA replication origin firing in human cells

    Kliszczak, M., Sedlackova, H., Pitchai, G. P., Streicher, W. W., Krejci, L. & Hickson, Ian David, 1 Dec 2015, In: OncoTarget. 6, 38, p. 40464-79 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  91. Published

    Interneuron Deficit Associates Attenuated Network Synchronization to Mismatch of Energy Supply and Demand in Aging Mouse Brains

    Jessen, S. B., Mathiesen, C., Lind, Barbara Lykke & Lauritzen, Martin, 2017, In: Cerebral Cortex. 27, 1, p. 646-659

    Research output: Contribution to journalJournal articleResearchpeer-review

  92. Published

    Interventions for age-related diseases: Shifting the paradigm

    Figueira, I., Fernandes, A., Mladenovic Djordjevic, A., Lopez-Contreras, Andres, Henriques, C. M., Selman, C., Ferreiro, E., Gonos, E. S., Trejo, J. L., Misra, J., Rasmussen, Lene Juel, Xapelli, S., Ellam, T. & Bellantuono, I., Dec 2016, In: Mechanisms of Ageing and Development. 160, p. 69-92 24 p.

    Research output: Contribution to journalReviewResearchpeer-review

  93. Published

    Introducing the hypothome: a way to integrate predicted proteins in interactomes

    Desler, Claus, Zambach, S., Suravajhala, P. & Rasmussen, Lene Juel, 2014, In: International Journal of Bioinformatics Research and Applications. 10, 6, p. 647-52 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  94. Published

    Involvement of the DNA mismatch repair system in cisplatin sensitivity of testicular germ cell tumours

    Rudolph, C., Melau, C., Nielsen, J. E., Jensen, K. V., Liu, D., Pena-Diaz, J., Meyts, E. R., Rasmussen, Lene Juel & Jorgensen, A., 2017, In: Cellular Oncology. 40, 4, p. 341-355

    Research output: Contribution to journalJournal articleResearchpeer-review

  95. Published

    Is There a Link between Mitochondrial Reserve Respiratory Capacity and Aging?

    Hansen, T. L., Rasmussen, Lene Juel, Desler, Claus, Frederiksen, J. B., Espersen, M. L. M. & Singh, K. K., 2012, In: Journal of Aging Research. 2012, p. 192503 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  96. Published

    Is it all in the baseline? Trajectories of chair stand performance over 4 years and their association with grey matter structure in older adults

    Demnitz, N., Gates, A. T., Mortensen, Erik Lykke, Garde, Ellen, Wimmelmann, Cathrine Lawaetz, Siebner, Hartwig Roman, Kjær, Michael & Boraxbekk, CJ, 2023, In: Human Brain Mapping. 44, 11, p. 4299-4309 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  97. Published

    Is lactate a volume transmitter of metabolic states of the brain?

    Bergersen, L. H. & Gjedde, Albert, 19 Jun 2012, In: Frontiers in Neuroenergetics. 4, Article 5, p. 1-6 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  98. Published

    Isometric abdominal wall muscle strength assessment in individuals with incisional hernia: a prospective reliability study

    Jensen, K. K., Kjær, Michael & Jørgensen, Lars Nannestad, Dec 2016, In: Hernia. 20, 6, p. 831-837

    Research output: Contribution to journalJournal articleResearchpeer-review

  99. Published

    Key Components of Human Myofibre Denervation and Neuromuscular Junction Stability are Modulated by Age and Exercise

    Søndenbroe, C., Bechshøft, C. J. L., Heisterberg, M. F., Jensen, S. M., Bomme, E., Schjerling, Peter, Karlsen, Anders, Kjær, Michael, Andersen, J. L. & Mackey, Abigail, 2020, In: Cells. 9, 4, 893.

    Research output: Contribution to journalJournal articleResearchpeer-review

  100. Published

    Knotty Problems during Mitosis: Mechanistic Insight into the Processing of Ultrafine DNA Bridges in Anaphase

    Sarlós, K., Biebricher, A., Petermann, E. J. G., Wuite, G. J. L. & Hickson, Ian David, 2017, In: Cold Spring Harbor Laboratory. Symposia on Quantitative Biology. 82, p. 187-195

    Research output: Contribution to journalJournal articleResearchpeer-review