Damage and Repair

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  1. Published

    Knotty Problems during Mitosis: Mechanistic Insight into the Processing of Ultrafine DNA Bridges in Anaphase

    Sarlós, K., Biebricher, A., Petermann, E. J. G., Wuite, G. J. L. & Hickson, Ian David, 2017, In: Cold Spring Harbor Laboratory. Symposia on Quantitative Biology. 82, p. 187-195

    Research output: Contribution to journal › Journal article › Research › peer-review

  2. Published

    Reconstitution of anaphase DNA bridge recognition and disjunction

    Sarlós, K., Biebricher, A. S., Bizard, A. H., Bakx, J. A. M., Ferreté-Bonastre, A. G., Modesti, M., Paramasivam, M., Yao, Q., Peterman, E. J. G., Wuite, G. J. L. & Hickson, Ian David, 2018, In: Nature Structural and Molecular Biology. 25, 9, p. 868-876 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Neurodegeneration in Accelerated Aging

    Scheibye-Knudsen, Morten, Nov 2016, In: Danish Medical Journal. 63, 11, 21 p., B5308.

    Research output: Contribution to journal › Review › Research › peer-review

  4. Published

    Neurodegeneration in accelerated aging

    Scheibye-Knudsen, Morten, 2016, 190 p.

    Research output: Book/Report › Doctoral thesis › Research

  5. Published

    Cockayne syndrome group A and B proteins converge on transcription-linked resolution of non-B DNA

    Scheibye-Knudsen, M., Tseng, A., Jensen, M. B., Scheibye-Alsing, K., Fang, E. F., Iyama, T., Bharti, S. K., Marosi, K., Froetscher, L., Kassahun, H., Eckley, D. M., Maul, R. W., Bastian, P., De, S., Ghosh, S., Nilsen, H., Goldberg, I. G., Mattson, M. P., Wilson, D. M. . III., Brosh, R. M. . J. & 2 others, Gorospe, M. & Bohr, Vilhelm, 1 Nov 2016, In: National Academy of Sciences. Proceedings. 113, 44, p. 12502-12507

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    A high-fat diet and NAD+ activate sirt1 to rescue premature aging in cockayne syndrome

    Scheibye-Knudsen, M., Mitchell, S. J., Fang, E. F., Iyama, T., Ward, T., Wang, J., Dunn, C. A., Singh, N., Veith, S., Hasan-Olive, M. M., Mangerich, A., Wilson, M. A., Mattson, M. P., Bergersen, L. H., Cogger, V. C., Warren, A., Le Couteur, D. G., Moaddel, R., Wilson, D. M., Croteau, D. L. & 2 others, De Cabo, R. & Bohr, Vilhelm, 4 Nov 2014, In: Cell Metabolism. 20, 5, p. 840-855 16 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    New hallmarks of ageing: a 2022 Copenhagen ageing meeting summary

    Schmauck-Medina, T., Molière, A., Lautrup, S., Zhang, J., Chlopicki, S., Madsen, H. B., Cao, S., Soendenbroe, C., Mansell, E., Vestergaard, M. B., Li, Z., Shiloh, Y., Opresko, P. L., Egly, J. M., Kirkwood, T., Verdin, E., Bohr, V. A., Cox, L. S., Stevnsner, T., Rasmussen, L. J. & 1 others, Fang, E. F., 2022, In: Aging. 14, 16, p. 6829-6839 11 p.

    Research output: Contribution to journal › Review › Research › peer-review

  8. Published

    Regulation of DNA double-strand break repair by ubiquitin and ubiquitin-like modifiers

    Schwertman, P., Bekker-Jensen, Simon Holst & Mailand, Niels, Jun 2016, In: Nature Reviews. Molecular Cell Biology. 17, 6, p. 379-94 16 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Viscoelastic Capillary Flow Cytometry

    Serhatlioglu, M., Jensen, E. A., Niora, M., Hansen, A. T., Nielsen, Christian Friberg, Jansman, M. M. T., Hosta-rigau, L., Dziegiel, Morten Hanefeld, Berg-sørensen, K., Hickson, Ian David & Kristensen, A., 2023, In: Advanced NanoBiomed Research. 3, 2, 2200137.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Development of a fiber-based microfluidic flow cytometry platform using viscoelastic fluids for polydisperse particle suspensions

    Serhatlioglu, M., Jensen, E. A., Niora, M., Hansen, A. T., Nielsen, Christian Friberg, Theresia Jansman, M. M., Hosta-Rigau, L., Dziegiel, Morten Hanefeld, Berg-Sørensen, K., Hickson, Ian David & Kristensen, A., 2022, In: Proceedings of SPIE - The International Society for Optical Engineering. 12198, 9 p., 1219802.

    Research output: Contribution to journal › Conference article › Research › peer-review

  11. Published

    Oxygen consumption and blood flow coupling in human motor cortex during intense finger tapping: implication for a role of lactate

    Seyedi Vafaee, M., Vang, K., Bergersen, L. H. & Gjedde, Albert, Oct 2012, In: Journal of Cerebral Blood Flow and Metabolism. 32, 10, p. 1859-68 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Ribosome impairment regulates intestinal stem cell identity via ZAKɑ activation

    Silva, J., Alkan, F., Ramalho, S., Snieckute, Goda, Prekovic, S., Garcia, A. K., Hernández-Pérez, S., van der Kammen, R., Barnum, D., Hoekman, L., Altelaar, M., Zwart, W., Suijkerbuijk, S. J. E., Bekker-Jensen, Simon Holst & Faller, W. J., 2022, In: Nature Communications. 13, 1, 4492.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    FBH1 helicase disrupts RAD51 filaments in vitro and modulates homologous recombination in mammalian cells

    Simandlova, J., Zagelbaum, J., Payne, M. J., Chu, W. K., Shevelev, I., Hanada, K., Chatterjee, S., Reid, D. A., Liu, Ying, Janscak, P., Rothenberg, E. & Hickson, Ian David, 22 Nov 2013, In: The Journal of Biological Chemistry. 288, 47, p. 34168-80 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Tendon properties in a mouse model of severe osteogenesis imperfecta

    Sinkam, L., Boraschi-Diaz, I., Svensson, R. B., Kjær, Michael, Komarova, S. V., Bergeron, R., Rauch, F. & Veilleux, L. N., 2023, In: Connective Tissue Research. 64, 3, p. 285-293

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Noninvasive Cu-64-ATSM and PET/CT Assessment of Hypoxia in Rat Skeletal Muscles and Tendons During Muscle Contractions

    Skovgaard, D., Kjær, Michael, Madsen, J. & Kjaer, A., 2009, In: Journal of Nuclear Medicine. 50, 6, p. 950-958 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    18F-fluorodeoxyglucose and PET/CT for noninvasive study of exercise-induced glucose uptake in rat skeletal muscle and tendon

    Skovgaard, D., Kjær, Michael, El Ali, Henrik H. & Kjær, Andreas, May 2009, In: European Journal of Nuclear Medicine and Molecular Imaging. 36, 5, p. 859-68 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    An advanced glycation endproduct (AGE)-rich diet promotes accumulation of AGEs in Achilles tendon

    Skovgaard, D., Svensson, R. B., Scheijen, J., Eliasson, P., Mogensen, P., Hag, Anne Mette Fisker, Kjær, Michael, Schalkwijk, C. G., Schjerling, P., Magnusson, Stig Peter & Couppé, C., Mar 2017, In: Physiological Reports. 5, 6, 7 p., e13215.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Noninvasive 64Cu-ATSM and PET/CT Assessment of Hypoxia in Rat Skeletal Muscles and Tendons During Muscle Contractions

    Skovgaard, D., Kjær, Michael, Madsen, J. & Kjær, Andreas, 2009, In: Journal of Nuclear Medicine. 50, 6, p. 950-958 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Thymidine kinase 1 deficient cells show increased survival rate after UV-induced DNA damage

    Skovgaard, T., Rasmussen, Lene Juel & Munch-Petersen, B., 2010, In: Nucleosides, Nucleotides and Nucleic Acids. 29, 4-6, p. 347-51 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Glia-Neuron Interactions in the Retina Can Be Studied in Cocultures of Muller Cells and Retinal Ganglion Cells

    Jensen, Dorte Skytt, Toft-Kehler, A. K., Braendstrup, C. T., Cejvanovic, S., Gurubaran, I. S., Bergersen, L. H. & Kolko, Miriam, 2016, In: Journal of Biomedicine and Biotechnology. 2016, 11 p., 1087647.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Molecular indicators of denervation in ageing human skeletal muscle

    Soendenbroe, C., Heisterberg, M. F., Schjerling, Peter, Karlsen, Anders, Kjær, Michael, Andersen, J. L. & Mackey, Abigail, 2019, In: Muscle & Nerve. 60, 4, p. 453-463 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Preserved stem cell content and innervation profile of elderly human skeletal muscle with lifelong recreational exercise

    Soendenbroe, C., Dahl, C. L., Meulengracht, C., Tamáš, M., Svensson, R. B., Schjerling, Peter, Kjær, Michael, Andersen, J. L. & Mackey, Abigail, 2022, In: The Journal of Physiology. 600, 8, p. 1969-1989

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Resting in bed - how quickly does the muscle lose its nerve?

    Soendenbroe, C., Mackey, Abigail & Kjær, Michael, 2021, In: The Journal of Physiology. 599, 12, p. 2995-2996

    Research output: Contribution to journal › Editorial › Research

  24. Published

    Metabolic reprogramming by Acly inhibition using SB-204990 alters glucoregulation and modulates molecular mechanisms associated with aging

    Sola-García, A., Cáliz-Molina, M. Á., Espadas, I., Petr, M., Panadero-Morón, C., González-Morán, D., Martín-Vázquez, M. E., Narbona-Pérez, Á. J., López-Noriega, L., Martínez-Corrales, G., López-Fernández-Sobrino, R., Carmona-Marin, L. M., Martínez-Force, E., Yanes, O., Vinaixa, M., López-López, D., Reyes, J. C., Dopazo, J., Martín, F., Gauthier, B. R. & 3 others, Scheibye-Knudsen, Morten, Capilla-González, V. & Martín-Montalvo, A., 2023, In: Communications Biology . 6, 250.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    CNOT6: A Novel Regulator of DNA Mismatch Repair

    Song, P., Liu, S., Liu, D., Keijzers, G., Bakula, Daniela Janina, Duan, S., de Wind, N., Ye, Z., Vakhrushev, Sergey, Scheibye-Knudsen, Morten & Rasmussen, Lene Juel, 2022, In: Cells. 11, 3, 521.

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    PICH acts as a force-dependent nucleosome remodeler

    Spakman, D., Clement, T. V. M., Biebricher, A. S., King, G. A., Singh, Manika Indrajit, Hickson, Ian David, Peterman, E. J. G. & Wuite, G. J. L., 2022, In: Nature Communications. 13, 7277.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    A Single Conserved Residue Mediates Binding of the Ribonucleotide Reductase Catalytic Subunit RRM1 to RRM2 and Is Essential for Mouse Development

    Specks, J., Lecona, E., Lopez-Contreras, Andres & Fernandez-Capetillo, O., Sep 2015, In: Molecular and Cellular Biology. 35, 17, p. 2910-2917 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    Enterococcus faecalis infection causes inflammation, intracellular oxphos-independent ROS production, and DNA damage in human gastric cancer cells

    Strickertsson, J. A. B., Desler, Claus, Martin-Bertelsen, T., Machado, A. M. D., Wadstrøm, T., Winther, Ole, Rasmussen, Lene Juel & Friis-Hansen, Lennart Jan, 2013, In: PLOS ONE. 8, 4, p. 1-13 13 p., e63147.

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    Enterococcus faecalis Infection and Reactive Oxygen Species Down-Regulates the miR-17-92 Cluster in Gastric Adenocarcinoma Cell Culture

    Strickertsson, J. A. B., Rasmussen, Lene Juel & Friis-Hansen, Lennart Jan, 28 Aug 2014, In: Genes. 5, 3, p. 726-38 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    Impact of bacterial infections on aging and cancer: Impairment of DNA repair and mitochondrial function of host cells

    Strickertsson, J. A. B., Desler, Claus & Rasmussen, Lene Juel, Aug 2014, In: Experimental Gerontology. 56, p. 164-174 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Published

    Bacterial infection increases risk of carcinogenesis by targeting mitochondria

    Strickertsson, J. A. B., Desler, Claus & Rasmussen, Lene Juel, Dec 2017, In: Seminars in Cancer Biology. 47, p. 95-100 6 p.

    Research output: Contribution to journal › Review › Research › peer-review

  32. Published

    Bloom syndrome DNA helicase deficiency is associated with oxidative stress and mitochondrial network changes

    Subramanian, V., Rodemoyer, B., Shastri, V., Rasmussen, Lene Juel, Desler, Claus & Schmidt, K. H., 2021, In: Scientific Reports. 11, 2157.

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. Published

    Effects of aging on human skeletal muscle after immobilization and retraining

    Suetta, Charlotte, Hvid, L. G., Justesen, L., Christensen, U., Neergaard, K., Simonsen, L., Ortenblad, N., Magnusson, Stig Peter, Kjær, Michael & Aagaard, P., 2009, In: Journal of Applied Physiology. 107, 4, p. 1172-80 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Published

    Coordinated increase in skeletal muscle fiber area and expression of IGF-I with resistance exercise in elderly post-operative patients

    Suetta, Charlotte, Clemmensen, C., Andersen, J. L., Magnusson, Stig Peter, Schjerling, P., Kjær, Michael, Suetta, C. A., Clemmensen, C., Andersen, J. L., Magnusson, Stig Peter, Schjerling, P. & Kjær, Michael, 1 Apr 2010, In: Growth Hormone & IGF Research. 20, 2, p. 134-40 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. Published

    Interaction between the helicases genetically linked to Fanconi anemia group J and Bloom's syndrome

    Suhasini, A. N., Rawtani, N. A., Wu, Y., Sommers, J. A., Sharma, S., Mosedale, G., North, P. S., Cantor, S. B., Hickson, Ian David & Brosh, R. M., 16 Feb 2011, In: E M B O Journal. 30, 4, p. 692-705 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    Effect of acute resistance exercise and sex on human patellar tendon structural and regulatory mRNA expression

    Sullivan, B. E., Carroll, C. C., Jemiolo, B., Trappe, S. W., Magnusson, S. P., Dossing, S., Kjær, Michael & Trappe, T. A., 2009, In: Journal of Applied Physiology. 106, 2, p. 468-475 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Published

    Multi-modal assessment of neurovascular coupling during cerebral ischaemia and reperfusion using remote middle cerebral artery occlusion

    Sutherland, B. A., Fordsmann, J. C., Martin, C., Neuhaus, A. A., Witgen, B. M., Hansen, H. P., Lønstrup, M., Couch, Y., Sibson, N. R., Lauritzen, Martin & Buchan, A. M., 2017, In: Journal of Cerebral Blood Flow and Metabolism. 37, 7, p. 2494-2508 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. Published

    Effect of aging and exercise on the tendon

    Svensson, R. B., Heinemeier, K. M., Couppé, Christian, Kjær, Michael & Magnusson, Stig Peter, 1 Dec 2016, In: Journal of Applied Physiology. 121, 6, p. 1237-1246 10 p.

    Research output: Contribution to journal › Review › Research › peer-review

  39. Published

    Mechanical properties of human patellar tendon collagen fibrils. An exploratory study of aging and sex

    Svensson, R. B., Eriksen, C. S., Tran, P. H. T., Kjær, Michael & Magnusson, Stig Peter, 2021, In: Journal of the Mechanical Behavior of Biomedical Materials. 124, 104864.

    Research output: Contribution to journal › Journal article › Research › peer-review

  40. Published

    Tensile force transmission in human patellar tendon fascicles is not mediated by glycosaminoglycans

    Svensson, R. B., Hassenkam, Tue, Hansen, P., Kjær, Michael & Magnusson, Stig Peter, 2011, In: Connective Tissue Research. 52, 5, p. 415-21 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. Published

    A Novel Rrm3 Function in Restricting DNA Replication via an Orc5-Binding Domain Is Genetically Separable from Rrm3 Function as an ATPase/Helicase in Facilitating Fork Progression

    Syed, S., Desler, Claus, Rasmussen, Lene Juel & Schmidt, K. H., Dec 2016, In: P L o S Genetics. 12, 12, 28 p., e1006451.

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. Published

    Key Components of Human Myofibre Denervation and Neuromuscular Junction Stability are Modulated by Age and Exercise

    Søndenbroe, C., Bechshøft, C. J. L., Heisterberg, M. F., Jensen, S. M., Bomme, E., Schjerling, Peter, Karlsen, Anders, Kjær, Michael, Andersen, J. L. & Mackey, Abigail, 2020, In: Cells. 9, 4, 893.

    Research output: Contribution to journal › Journal article › Research › peer-review

  43. Published

    Hyposalivation and Poor Dental Health Status Are Potential Correlates of Age-Related Cognitive Decline in Late Midlife in Danish Men

    Sørensen, Christiane Elisabeth, Hansen, N. L., Mortensen, Erik Lykke, Lauritzen, Martin, Osler, Merete & Pedersen, Anne Marie Lynge, 2018, In: Frontiers in Aging Neuroscience. 10, p. 1-7 7 p., 10.

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Published

    Elevated p16ink4a Expression in Human Labial Salivary Glands as a Potential Correlate of Cognitive Aging in Late Midlife

    Sørensen, Christiane Elisabeth, Tritsaris, Katerina, Reibel, Jesper, Lauritzen, Martin, Mortensen, Erik Lykke, Osler, Merete & Pedersen, Anne Marie Lynge, 2016, In: PloS one. 11, 3, p. e0152612

    Research output: Contribution to journal › Journal article › Research › peer-review

  45. Published

    Associations between xerostomia, histopathological alterations, and autonomic innervation of labial salivary glands in men in late midlife

    Sørensen, Christiane Elisabeth, Larsen, J. O., Reibel, Jesper, Lauritzen, Martin, Mortensen, Erik Lykke, Osler, Merete & Pedersen, Anne Marie Lynge, Sep 2014, In: Experimental Gerontology. 57, p. 211-217 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  46. Published

    Validation of hippocampal texture for early Alzheimer’s disease detection: generalization to independent cohorts and extrapolation to very early signs of dementia

    Sørensen, L., Igel, Christian, Hansen, N. L., Lauritzen, Martin, Osler, Merete, Rostrup, Egill & Nielsen, Mads, 2014, In: Alzheimer's & Dementia. 10, 4, Supplement, p. P133 1 p.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  47. Published

    Early detection of Alzheimer's disease using MRI hippocampal texture

    Sørensen, L., Igel, Christian, Hansen, N. L., Osler, Merete, Lauritzen, Martin, Rostrup, Egill & Nielsen, Mads, 2016, In: Human Brain Mapping. 37, 3, p. 1148-1161 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  48. Published

    Mutual stimulatory signaling between human myogenic cells and rat cerebellar neurons

    Tamáš, M., Pankratova, Stanislava, Schjerling, Peter, Soendenbroe, C., Yeung, C. C., Pennisi, C. P., Jakobsen, J. R., Krogsgaard, Michael R., Kjær, Michael & Mackey, Abigail, 2021, In: Physiological Reports. 9, 21, e15077.

    Research output: Contribution to journal › Journal article › Research › peer-review

  49. Published

    Chromosome instability syndromes

    Taylor, A. M. R., Rothblum-Oviatt, C., Ellis, N. A., Hickson, Ian David, Meyer, S., Crawford, T. O., Smogorzewska, A., Pietrucha, B., Weemaes, C. & Stewart, G. S., 2019, In: Nature Reviews. Disease Primers. 5, 20 p., 64.

    Research output: Contribution to journal › Review › Research › peer-review

  50. Published

    Application of a 5-tiered scheme for standardized classification of 2,360 unique mismatch repair gene variants in the InSiGHT locus-specific database

    Thompson, B. A., Spurdle, A. B., Plazzer, J-P., Greenblatt, M. S., Akagi, K., Al-Mulla, F., Bapat, B., Bernstein, I., Capellá, G., den Dunnen, J. T., du Sart, D., Fabre, A., Farrell, M. P., Farrington, S. M., Frayling, I. M., Frebourg, T., Goldgar, D. E., Heinen, C. D., Holinski-Feder, E., Kohonen-Corish, M. & 31 others, Robinson, K. L., Leung, S. Y., Martins, A., Moller, P., Morak, M., Nystrom, M., Peltomaki, P., Pineda, M., Qi, M., Ramesar, R., Rasmussen, Lene Juel, Royer-Pokora, B., Scott, R. J., Sijmons, R., Tavtigian, S. V., Tops, C. M., Weber, T., Wijnen, J., Woods, M. O., Macrae, F., Genuardi, M., Castillejo, A., Sexton, A., Chan, A. K. W., Viel, A., Blanco, A., French, A., Laner, A., Wagner, A., van den Ouweland, A. & on behalf of InSiGHT, O. B. O. I., Feb 2014, In: Nature Genetics. 46, 2, p. 107-115 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  51. Published

    Initial brain aging: heterogeneity of mitochondrial size is associated with decline in complex I-linked respiration in cortex and hippocampus

    Thomsen, Kirsten Joan, Yokota, T., Hasan-Olive, M. M., Sherazi, N., Fakouri, N. B., Desler, Claus, Regnell, C. E., Larsen, S., Rasmussen, Lene Juel, Dela, Flemming, Bergersen, L. H. & Lauritzen, Martin, 2018, In: Neurobiology of Aging. 61, p. 215-224 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  52. Published

    Principal cell spiking, postsynaptic excitation, and oxygen consumption in the rat cerebellar cortex

    Thomsen, Kirsten Joan, Piilgaard, H., Gjedde, Albert, Bonvento, G., Lauritzen, Martin, Thomsen, K., Hansen, H. P., Gjedde, A., Bonvento, G. & Lauritzen, Martin, 1 Sep 2009, In: Journal of Neurophysiology. 102, 3, p. 1503-12 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  53. Published

    Histone H1 couples initiation and amplification of ubiquitin signalling after DNA damage

    Thorslund, T., Ripplinger, A., Hoffmann, Saskia, Wild, T., Uckelmann, M., Villumsen, B., Narita, Takeo, Sixma, T. K., Choudhary, Chunaram, Bekker-Jensen, Simon Holst & Mailand, Niels, 19 Nov 2015, In: Nature. 527, 7578, p. 389-93 5 p.

    Research output: Contribution to journal › Letter › Research › peer-review

  54. Published

    Oxidative Stress-Induced Dysfunction of Muller Cells During Starvation

    Toft-Kehler, A. K., Gurubaran, I. S., Desler, Claus, Rasmussen, Lene Juel, Jensen, Dorte Skytt & Kolko, Miriam, May 2016, In: Investigative Ophthalmology & Visual Science. 57, 6, p. 2721-2728

    Research output: Contribution to journal › Journal article › Research › peer-review

  55. Published

    ATR Prohibits Replication Catastrophe by Preventing Global Exhaustion of RPA

    Toledo Lazaro, L. I., Altmeyer, M., Rask, M., Lukas, Claudia, Larsen, D. H., Povlsen, L. K., Bekker-Jensen, Simon Holst, Mailand, Niels, Bartek, J. & Lukas, Jiri, 21 Nov 2013, In: Cell. 155, 5, p. 1088-1103 16 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  56. Published

    Centriolar satellites: key mediators of centrosome functions

    Tollenaere, M. A. X., Mailand, Niels & Bekker-Jensen, Simon Holst, Jan 2015, In: Cellular and molecular life sciences : CMLS. 73, 1, p. 11-23 13 p.

    Research output: Contribution to journal › Review › Research › peer-review

  57. Published

    p38- and MK2-dependent signalling promotes stress-induced centriolar satellite remodelling via 14-3-3-dependent sequestration of CEP131/AZI1

    Tollenaere, M. A. X., Villumsen, B. H., Blasius, M., Nielsen, J. C., Wagner, S. A., Bartek, J., Beli, P., Mailand, Niels & Bekker-Jensen, Simon Holst, 30 Nov 2015, In: Nature Communications. 6, p. 1-12 12 p., 10075.

    Research output: Contribution to journal › Journal article › Research › peer-review

  58. Published

    The influence of fibrillin‐1 and physical activity upon tendon tissue morphology and mechanical properties in mice

    Tran, P. H. T., Skrba, T., Wondimu, E., Galatioto, G., Svensson, R. B., Olesen, A. T., Mackey, Abigail, Magnusson, Stig Peter, Ramirez, F. & Kjær, Michael, 1 Nov 2019, In: Physiological Reports. 7, 21, 9 p., e14267 .

    Research output: Contribution to journal › Journal article › Research › peer-review

  59. Published

    Early development of tendinopathy in humans: Sequence of pathological changes in structure and tissue turnover signaling

    Tran, P. H. T., Malmgaard-Clausen, N. M., Puggaard, R. S., Svensson, R. B., Nybing, J. D., Hansen, P., Schjerling, P., Zinglersen, A. H., Couppé, Christian, Boesen, Mikael Ploug, Magnusson, Stig Peter & Kjær, Michael, 2020, In: FASEB Journal. 34, 1, p. 776-788 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  60. Published

    Alternative translation initiation generates a functionally distinct isoform of the stress-activated kinase MK2

    Trulley, P., Snieckute, Goda, Bekker-Jensen, D. B., Menon, M. B., Freund, R., Kotlyarov, A., Olsen, Jesper Velgaard, Diaz-Muñoz, M. D., Turner, M., Bekker-Jensen, Simon Holst, Gaestel, M. & Tiedje, C., 2018, bioRxiv, 46 p. (bioRxiv).

    Research output: Working paper › Preprint › Research

  61. Published

    Human derived tendon cells contribute to myotube formation in vitro

    Tsuchiya, Y., Bayer, M. L., Schjerling, Peter, Soendenbroe, C. & Kjær, Michael, 2022, In: Experimental Cell Research. 417, 1, 113164.

    Research output: Contribution to journal › Journal article › Research › peer-review

  62. Published

    Enhancement of Astroglial Aerobic Glycolysis by Extracellular Lactate-Mediated Increase in cAMP

    Vardjan, N., Chowdhury, H. H., Horvat, A., Velebit, J., Malnar, M., Muhič, M., Kreft, M., Krivec, Š. G., Bobnar, S. T., Miš, K., Pirkmajer, S., Offermanns, S., Henriksen, G., Storm-mathisen, J., Bergersen, L. H. & Zorec, R., 2018, In: Frontiers in Molecular Neuroscience. 11, 15 p., 148.

    Research output: Contribution to journal › Journal article › Research › peer-review

  63. Published

    Inducible Degradation of the Human SMC5/6 Complex Reveals an Essential Role Only during Interphase

    Venegas, A. B., Natsume, T., Kanemaki, M. & Hickson, Ian David, 2020, In: Cell Reports. 31, 3, 20 p., 107533.

    Research output: Contribution to journal › Journal article › Research › peer-review

  64. Published

    Local administration of growth hormone stimulates tendon collagen synthesis in elderly men

    Vestergaard, P. E., Jørgensen, J. O. L., Olesen, J., Bosnjak, E., Holm, L., Frystyk, J., Langberg, Henning, Kjær, Michael & Hansen, M. D., Nov 2012, In: Journal of Applied Physiology. 113, 9, p. 1432-8 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  65. Published

    A new cellular stress response that triggers centriolar satellite reorganization and ciliogenesis

    Villumsen, B. H., Danielsen, J. R., Povlsen, L., Sylvestersen, K. B., Merdes, A., Beli, P., Yang, Y., Choudhary, Chunaram, Nielsen, Michael Lund, Mailand, Niels & Bekker-Jensen, Simon Holst, 11 Oct 2013, In: E M B O Journal. 32, 23, p. 3029-3040

    Research output: Contribution to journal › Journal article › Research › peer-review

  66. Published

    Essential Roles of Lactate in Müller Cell Survival and Function

    Vohra, Rupali, Aldana, Blanca, Jensen, Dorte Skytt, Freude, Kristine, Waagepetersen, Helle S., Bergersen, L. H. & Kolko, Miriam, 1 Dec 2018, In: Molecular Neurobiology. 55, 12, p. 9108-9121 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  67. Published

    Prevention of Cell Death by Activation of Hydroxycarboxylic Acid Receptor 1 (GPR81) in Retinal Explants

    Vohra, Rupali, Sanz-Morello, B., Tams, A. L. M., Mouhammad, Zaynab Ahmad, Freude, Kristine, Hannibal, Jens, Aldana, Blanca, Bergersen, L. H. & Kolko, Miriam, 2022, In: Cells. 11, 13, 2098.

    Research output: Contribution to journal › Journal article › Research › peer-review

  68. Published

    Potential metabolic markers in glaucoma and their regulation in response to hypoxia

    Vohra, Rupali, Dalgaard, L. M., Vibaek, J., Langbøl, Mia Aggergaard, Bergersen, L. H., Olsen, N. V., Hassel, B., Chaudhry, F. A. & Kolko, Miriam, 28 Jan 2019, In: Acta Ophthalmologica. 97, 6, p. 567-576

    Research output: Contribution to journal › Journal article › Research › peer-review

  69. Published

    Disturbed mitochondrial function restricts glutamate uptake in the human Müller glia cell line, MIO-M1

    Vohra, Rupali, Gurubaran, I. S., Henriksen, U., Bergersen, L. H., Rasmussen, Lene Juel, Desler, C., Jensen, Dorte Skytt & Kolko, Miriam, 2017, In: Mitochondrion. 36, p. 52-59

    Research output: Contribution to journal › Journal article › Research › peer-review

  70. Published

    Dual Properties of Lactate in Müller Cells: The Effect of GPR81 Activation

    Vohra, Rupali, Aldana, Blanca, Waagepetersen, Helle S., Bergersen, L. H. & Kolko, Miriam, 1 Mar 2019, In: Investigative Ophthalmology & Visual Science. 60, 4, p. 999-1008 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  71. Published

    Lactate-Mediated Protection of Retinal Ganglion Cells

    Vohra, Rupali, Aldana, Blanca, Bulli, G., Jensen, Dorte Skytt, Waagepetersen, Helle S., Bergersen, L. H. & Kolko, Miriam, 19 Apr 2019, In: Journal of Molecular Biology. 431, 9, p. 1878-1888 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  72. Published

    No detectable remodelling in adult human menisci: an analysis based on the C14 bomb pulse

    Våben, C., Heinemeier, K. M., Schjerling, P., Olsen, J., Petersen, Michael Mørk, Kjær, Michael & Krogsgaard, Michael R., 2020, In: British Journal of Sports Medicine. 54, 23, p. 1433-1437

    Research output: Contribution to journal › Journal article › Research › peer-review

  73. Published

    Subjective sleep quality and daytime sleepiness in late midlife and their association with age-related changes in cognition

    Waller, K. L., Mortensen, Erik Lykke, Avlund, K., Osler, Merete, Fagerlund, Birgitte, Lauritzen, Martin & Jennum, Poul, Jan 2016, In: Sleep Medicine. 17, p. 165-73 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  74. Published

    Melatonin and cortisol profiles in late midlife and their association with age-related changes in cognition

    Waller, K. L., Mortensen, Erik Lykke, Avlund, K., Fagerlund, Birgitte, Lauritzen, Martin, Gammeltoft, S. & Jennum, Poul, 2016, In: Nature and Science of Sleep. 8, p. 47-53 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  75. Published

    Sleep efficiency and neurophysiological patterns in middle-aged men are associated with cognitive change over their adult life course

    Waser, M., Lauritzen, Martin, Fagerlund, Birgitte, Osler, Merete, Mortensen, Erik Lykke, Sørensen, H. B. D. & Jennum, Poul, 2019, In: Journal of Sleep Research. 28, 4, 9 p., e12793.

    Research output: Contribution to journal › Journal article › Research › peer-review

  76. Published

    EEG correlates of visual short-term memory in older age vary with adult lifespan cognitive development

    Wiegand, I., Lauritzen, Martin, Osler, Merete, Mortensen, Erik Lykke, Rostrup, E., Rask, L., Richard, N., Horwitz, A., Benedek, K., Vangkilde, Signe & Petersen, Anders, 2018, In: Neurobiology of Aging. 62, p. 210-220 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  77. Published

    Variation in the risk of colorectal cancer in families with Lynch syndrome: a retrospective cohort study

    The International Mismatch Repair Consortium, T. I. M. R. C., Jul 2021, In: The Lancet Oncology. 22, 7, p. 1014-1022 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  78. Published

    The prevention and resolution of DNA replication–transcription conflicts in eukaryotic cells

    Wu, Wei, Hickson, Ian David & Liu, Ying, 2020, In: Genome Instability & Disease. 1, 3, p. 114–128 15 p.

    Research output: Contribution to journal › Review › Research › peer-review

  79. Published

    RTEL1 suppresses G-quadruplex-associated R-loops at difficult-to-replicate loci in the human genome

    Wu, Wei, Bhowmick, Rahul, Vogel, Ivan, Özer, Ö., Ghisays, F., Thakur, R. S., Sanchez de Leon, E., Richter, P. H., Ren, L., Petrini, J. H., Hickson, Ian David & Liu, Ying, 2020, In: Nature Structural & Molecular Biology. 27, 5, p. 424-437 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  80. Published

    Replication Stress Induces ATR/CHK1-Dependent Nonrandom Segregation of Damaged Chromosomes

    Xing, M., Zhang, F., Liao, H., Chen, S., Che, L., Wang, X., Bao, Z., Ji, F., Chen, G., Zhang, H., Li, W., Chen, Z., Liu, Ying, Hickson, Ian David, Shen, H. & Ying, S., 2020, In: Molecular Cell. 78, 4, p. 714-724.e5

    Research output: Contribution to journal › Journal article › Research › peer-review

  81. Published

    Acute MUS81 depletion leads to replication fork slowing and a constitutive DNA damage response

    Xing, M., Wang, X., Palmai-Pallag, T., Shen, H., Helleday, T., Hickson, Ian David & Ying, S., 2015, In: OncoTarget. 6, 35, p. 37638-37646 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  82. Published

    Human topoisomerase IIIalpha is a single-stranded DNA decatenase that is stimulated by BLM and RMI1

    Yang, J., Bachrati, C. Z., Ou, J., Hickson, Ian David & Brown, G. W., 2010, In: Journal of Biological Chemistry. 285, 28, p. 21426-36 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  83. Published

    BLM and RMI1 Alleviate RPA Inhibition of TopoIIIa Decatenase Activity

    Yang, J., Bachrati, C. Z., Hickson, Ian David & Brown, G. W., Jul 2012, In: P L o S One. 7, 7, p. e41208

    Research output: Contribution to journal › Journal article › Research › peer-review

  84. Published

    Circadian regulation of protein cargo in extracellular vesicles

    Yeung, Ching-Yan Chloé, Dondelinger, F., Schoof, E. M., Georg, B., Lu, Y., Zheng, Z., Zhang, J., Hannibal, Jens, Fahrenkrug, J. & Kjær, Michael, 2022, In: Science Advances. 8, 14, 13 p., eabc9061.

    Research output: Contribution to journal › Journal article › Research › peer-review

  85. Published

    Proteomics identifies differences in fibrotic potential of extracellular vesicles from human tendon and muscle fibroblasts

    Yeung, C. C., Schoof, E. M., Tamáš, M., Mackey, Abigail & Kjær, Michael, 2020, In: Cell Communication and Signaling. 18, 1, 15 p., 177.

    Research output: Contribution to journal › Journal article › Research › peer-review

  86. Published

    MUS81 promotes common fragile site expression

    Ying, S., Minocherhomji, S., Chan, K. L., Palmai-Pallag, T., Chu, W. K., Wass, T. A., Mankouri, H. W., Liu, Ying & Hickson, Ian David, Aug 2013, In: Nature Cell Biology. 15, 8, p. 1001-1007 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  87. Published

    Fanconi anaemia proteins are associated with sister chromatid bridging in mitosis

    Ying, S. & Hickson, Ian David, 1 Apr 2011, In: U H O D. 93, 4, p. 440-5 6 p.

    Research output: Contribution to journal › Review › Research › peer-review

  88. Published

    Acute fatigue impairs neuromuscular activity of anterior cruciate ligament-agonist muscles in female team handball players

    Zebis, M. K., Bencke, J., Andersen, L. L., Alkjær, Tine, Suetta, Charlotte, Mortensen, P., Kjær, Michael, Aagaard, P., Zebis, M. K., Bencke, J., Andersen, L. L., Alkjaer, T., Suetta, C., Mortensen, P., Kjær, Michael & Aagaard, P., 2011, In: Scandinavian Journal of Medicine & Science in Sports Online. 21, 6, p. 833-40 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  89. Published

    Identification of athletes at future risk of anterior cruciate ligament ruptures by neuromuscular screening

    Zebis, M. K., Andersen, L. L., Bencke, J., Kjær, Michael & Aagaard, P., 2009, In: American Journal of Sports Medicine. 37, 10, p. 1967-73 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  90. Published

    DNA replication stress and its impact on chromosome segregation and tumorigenesis

    Zhang, B. N., Bueno Venegas, A., Hickson, Ian David & Chu, W. K., 2019, In: Seminars in Cancer Biology. 55, p. 61-69

    Research output: Contribution to journal › Journal article › Research › peer-review

  91. Published

    Regional differences in turnover, composition, and mechanics of the porcine flexor tendon

    Zhang, C., Svensson, R. B., Couppé, Christian, Schjerling, P., Skovgaard, D., Kjær, Michael & Magnusson, Stig Peter, 2020, In: Connective Tissue Research. 61, 5, p. 475-484

    Research output: Contribution to journal › Journal article › Research › peer-review

  92. Published

    Regional collagen turnover and composition of the human patellar tendon

    Zhang, C., Couppé, Christian, Scheijen, J. L. J. M., Schalkwijk, C. G., Kjær, Michael, Magnusson, Stig Peter & Svensson, R. B., 2020, In: Journal of Applied Physiology. 128, 4, p. 884-891

    Research output: Contribution to journal › Journal article › Research › peer-review

  93. Published

    Comparison of Tenocyte Populations from the Core and Periphery of Equine Tendons

    Zhang, C., Svensson, R. B., Montagna, C., Carstensen, Helena, Buhl, Rikke, Schoof, E. M., Kjær, Michael, Magnusson, Stig Peter & Yeung, C. Y. C., 2020, In: Journal of Proteome Research. 19, 10, p. 4137-4144 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  94. Published

    Histone malonylation is regulated by SIRT5 and KAT2A

    Zhang, R., Bons, J., Scheidemantle, G., Liu, X., Bielska, O., Carrico, C., Rose, J., Heckenbach, Indra John, Scheibye-Knudsen, Morten, Schilling, B. & Verdin, E., 2023, In: iScience. 26, 3, 106193.

    Research output: Contribution to journal › Journal article › Research › peer-review

  95. Published

    Artificial intelligence for aging and longevity research: Recent advances and perspectives

    Zhavoronkov, A., Mamoshina, P., Vanhaelen, Q., Scheibye-Knudsen, Morten, Moskalev, A. & Aliper, A., 2019, In: Ageing Research Reviews. 49, p. 49-66 18 p.

    Research output: Contribution to journal › Review › Research › peer-review

  96. Published

    An anti-inflammatory phenotype in visceral adipose tissue of old lean mice, augmented by exercise

    Ziegler, A. K., Damgaard, A., Mackey, Abigail, Schjerling, Peter, Magnusson, Stig Peter, Olesen, A. T., Kjær, Michael & Schéele, Camilla Charlotte Nielsen, 2019, In: Scientific Reports. 9, 11 p., 12069.

    Research output: Contribution to journal › Journal article › Research › peer-review

  97. Published

    The effect of resistance exercise upon age-related systemic and local skeletal muscle inflammation

    Ziegler, A. K., Jensen, S. M., Schjerling, P., Mackey, Abigail, Andersen, J. L. & Kjær, Michael, 2019, In: Experimental Gerontology. 121, p. 19-32

    Research output: Contribution to journal › Journal article › Research › peer-review

  98. Published

    Mitochondrial dysfunction induced by variation in the non-coding genome – A proposed workflow to improve diagnostics

    du Mee, D. J. M., Bak, M., Østergaard, Elsebet & Rasmussen, Lene Juel, 2020, In: Mitochondrion. 53, p. 255-259

    Research output: Contribution to journal › Journal article › Research › peer-review

  99. Published

    Human cancer cells utilize mitotic DNA synthesis to resist replication stress at telomeres regardless of their telomere maintenance mechanism

    Özer, Ö., Bhowmick, Rahul, Liu, Ying & Hickson, Ian David, 2018, In: OncoTarget. 9, 22, p. 15836-15846 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  100. Published

    Pathways for maintenance of telomeres and common fragile sites during DNA replication stress

    Özer, Ö. & Hickson, Ian David, 2018, In: Open Biology. 8, 4, 11 p., 180018.

    Research output: Contribution to journal › Review › Research › peer-review

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