Damage and Repair

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  1. Published

    RNF8 and RNF168 but not HERC2 are required for DNA damage-induced ubiquitylation in chicken DT40 cells

    Østergaard, Vibe Hallundbæk, Pentzold, C., Pedersen, R. T., Iosif, S., Alpi, A., Bekker-Jensen, Simon Holst, Mailand, Niels & Lisby, Michael, 2012, In: D N A Repair. 11, 11, p. 892–905 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  2. Published

    Human cancer cells utilize mitotic DNA synthesis to resist replication stress at telomeres regardless of their telomere maintenance mechanism

    Özer, Ö., Bhowmick, Rahul, Liu, Ying & Hickson, Ian David, 2018, In: OncoTarget. 9, 22, p. 15836-15846 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Pathways for maintenance of telomeres and common fragile sites during DNA replication stress

    Özer, Ö. & Hickson, Ian David, 2018, In: Open Biology. 8, 4, 11 p., 180018.

    Research output: Contribution to journal › Review › Research › peer-review

  4. Published

    Mitochondrial dysfunction induced by variation in the non-coding genome – A proposed workflow to improve diagnostics

    du Mee, D. J. M., Bak, M., Østergaard, Elsebet & Rasmussen, Lene Juel, 2020, In: Mitochondrion. 53, p. 255-259

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    The effect of resistance exercise upon age-related systemic and local skeletal muscle inflammation

    Ziegler, A. K., Jensen, S. M., Schjerling, P., Mackey, Abigail, Andersen, J. L. & Kjær, Michael, 2019, In: Experimental Gerontology. 121, p. 19-32

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    An anti-inflammatory phenotype in visceral adipose tissue of old lean mice, augmented by exercise

    Ziegler, A. K., Damgaard, A., Mackey, Abigail, Schjerling, Peter, Magnusson, Stig Peter, Olesen, A. T., Kjær, Michael & Schéele, Camilla Charlotte Nielsen, 2019, In: Scientific Reports. 9, 11 p., 12069.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Artificial intelligence for aging and longevity research: Recent advances and perspectives

    Zhavoronkov, A., Mamoshina, P., Vanhaelen, Q., Scheibye-Knudsen, Morten, Moskalev, A. & Aliper, A., 2019, In: Ageing Research Reviews. 49, p. 49-66 18 p.

    Research output: Contribution to journal › Review › Research › peer-review

  8. Published

    Histone malonylation is regulated by SIRT5 and KAT2A

    Zhang, R., Bons, J., Scheidemantle, G., Liu, X., Bielska, O., Carrico, C., Rose, J., Heckenbach, Indra John, Scheibye-Knudsen, Morten, Schilling, B. & Verdin, E., 2023, In: iScience. 26, 3, 106193.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Regional differences in turnover, composition, and mechanics of the porcine flexor tendon

    Zhang, C., Svensson, R. B., Couppé, Christian, Schjerling, P., Skovgaard, D., Kjær, Michael & Magnusson, Stig Peter, 2020, In: Connective Tissue Research. 61, 5, p. 475-484

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Regional collagen turnover and composition of the human patellar tendon

    Zhang, C., Couppé, Christian, Scheijen, J. L. J. M., Schalkwijk, C. G., Kjær, Michael, Magnusson, Stig Peter & Svensson, R. B., 2020, In: Journal of Applied Physiology. 128, 4, p. 884-891

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Comparison of Tenocyte Populations from the Core and Periphery of Equine Tendons

    Zhang, C., Svensson, R. B., Montagna, C., Carstensen, Helena, Buhl, Rikke, Schoof, E. M., Kjær, Michael, Magnusson, Stig Peter & Yeung, C. Y. C., 2020, In: Journal of Proteome Research. 19, 10, p. 4137-4144 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    DNA replication stress and its impact on chromosome segregation and tumorigenesis

    Zhang, B. N., Bueno Venegas, A., Hickson, Ian David & Chu, W. K., 2019, In: Seminars in Cancer Biology. 55, p. 61-69

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Identification of athletes at future risk of anterior cruciate ligament ruptures by neuromuscular screening

    Zebis, M. K., Andersen, L. L., Bencke, J., Kjær, Michael & Aagaard, P., 2009, In: American Journal of Sports Medicine. 37, 10, p. 1967-73 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Acute fatigue impairs neuromuscular activity of anterior cruciate ligament-agonist muscles in female team handball players

    Zebis, M. K., Bencke, J., Andersen, L. L., Alkjær, Tine, Suetta, Charlotte, Mortensen, P., Kjær, Michael, Aagaard, P., Zebis, M. K., Bencke, J., Andersen, L. L., Alkjaer, T., Suetta, C., Mortensen, P., Kjær, Michael & Aagaard, P., 2011, In: Scandinavian Journal of Medicine & Science in Sports Online. 21, 6, p. 833-40 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    MUS81 promotes common fragile site expression

    Ying, S., Minocherhomji, S., Chan, K. L., Palmai-Pallag, T., Chu, W. K., Wass, T. A., Mankouri, H. W., Liu, Ying & Hickson, Ian David, Aug 2013, In: Nature Cell Biology. 15, 8, p. 1001-1007 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Fanconi anaemia proteins are associated with sister chromatid bridging in mitosis

    Ying, S. & Hickson, Ian David, 1 Apr 2011, In: U H O D. 93, 4, p. 440-5 6 p.

    Research output: Contribution to journal › Review › Research › peer-review

  17. Published

    Proteomics identifies differences in fibrotic potential of extracellular vesicles from human tendon and muscle fibroblasts

    Yeung, C. C., Schoof, E. M., Tamáš, M., Mackey, Abigail & Kjær, Michael, 2020, In: Cell Communication and Signaling. 18, 1, 15 p., 177.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Circadian regulation of protein cargo in extracellular vesicles

    Yeung, Ching-Yan Chloé, Dondelinger, F., Schoof, E. M., Georg, B., Lu, Y., Zheng, Z., Zhang, J., Hannibal, Jens, Fahrenkrug, J. & Kjær, Michael, 2022, In: Science Advances. 8, 14, 13 p., eabc9061.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Human topoisomerase IIIalpha is a single-stranded DNA decatenase that is stimulated by BLM and RMI1

    Yang, J., Bachrati, C. Z., Ou, J., Hickson, Ian David & Brown, G. W., 2010, In: Journal of Biological Chemistry. 285, 28, p. 21426-36 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    BLM and RMI1 Alleviate RPA Inhibition of TopoIIIa Decatenase Activity

    Yang, J., Bachrati, C. Z., Hickson, Ian David & Brown, G. W., Jul 2012, In: P L o S One. 7, 7, p. e41208

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Replication Stress Induces ATR/CHK1-Dependent Nonrandom Segregation of Damaged Chromosomes

    Xing, M., Zhang, F., Liao, H., Chen, S., Che, L., Wang, X., Bao, Z., Ji, F., Chen, G., Zhang, H., Li, W., Chen, Z., Liu, Ying, Hickson, Ian David, Shen, H. & Ying, S., 2020, In: Molecular Cell. 78, 4, p. 714-724.e5

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Acute MUS81 depletion leads to replication fork slowing and a constitutive DNA damage response

    Xing, M., Wang, X., Palmai-Pallag, T., Shen, H., Helleday, T., Hickson, Ian David & Ying, S., 2015, In: OncoTarget. 6, 35, p. 37638-37646 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    The prevention and resolution of DNA replication–transcription conflicts in eukaryotic cells

    Wu, Wei, Hickson, Ian David & Liu, Ying, 2020, In: Genome Instability & Disease. 1, 3, p. 114–128 15 p.

    Research output: Contribution to journal › Review › Research › peer-review

  24. Published

    RTEL1 suppresses G-quadruplex-associated R-loops at difficult-to-replicate loci in the human genome

    Wu, Wei, Bhowmick, Rahul, Vogel, Ivan, Özer, Ö., Ghisays, F., Thakur, R. S., Sanchez de Leon, E., Richter, P. H., Ren, L., Petrini, J. H., Hickson, Ian David & Liu, Ying, 2020, In: Nature Structural & Molecular Biology. 27, 5, p. 424-437 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Variation in the risk of colorectal cancer in families with Lynch syndrome: a retrospective cohort study

    The International Mismatch Repair Consortium, T. I. M. R. C., Jul 2021, In: The Lancet Oncology. 22, 7, p. 1014-1022 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    EEG correlates of visual short-term memory in older age vary with adult lifespan cognitive development

    Wiegand, I., Lauritzen, Martin, Osler, Merete, Mortensen, Erik Lykke, Rostrup, E., Rask, L., Richard, N., Horwitz, A., Benedek, K., Vangkilde, Signe & Petersen, Anders, 2018, In: Neurobiology of Aging. 62, p. 210-220 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    Sleep efficiency and neurophysiological patterns in middle-aged men are associated with cognitive change over their adult life course

    Waser, M., Lauritzen, Martin, Fagerlund, Birgitte, Osler, Merete, Mortensen, Erik Lykke, Sørensen, H. B. D. & Jennum, Poul, 2019, In: Journal of Sleep Research. 28, 4, 9 p., e12793.

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    Subjective sleep quality and daytime sleepiness in late midlife and their association with age-related changes in cognition

    Waller, K. L., Mortensen, Erik Lykke, Avlund, K., Osler, Merete, Fagerlund, Birgitte, Lauritzen, Martin & Jennum, Poul, Jan 2016, In: Sleep Medicine. 17, p. 165-73 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    Melatonin and cortisol profiles in late midlife and their association with age-related changes in cognition

    Waller, K. L., Mortensen, Erik Lykke, Avlund, K., Fagerlund, Birgitte, Lauritzen, Martin, Gammeltoft, S. & Jennum, Poul, 2016, In: Nature and Science of Sleep. 8, p. 47-53 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    No detectable remodelling in adult human menisci: an analysis based on the C14 bomb pulse

    Våben, C., Heinemeier, K. M., Schjerling, P., Olsen, J., Petersen, Michael Mørk, Kjær, Michael & Krogsgaard, Michael R., 2020, In: British Journal of Sports Medicine. 54, 23, p. 1433-1437

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Published

    Essential Roles of Lactate in Müller Cell Survival and Function

    Vohra, Rupali, Aldana, Blanca, Jensen, Dorte Skytt, Freude, Kristine, Waagepetersen, Helle S., Bergersen, L. H. & Kolko, Miriam, 1 Dec 2018, In: Molecular Neurobiology. 55, 12, p. 9108-9121 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. Published

    Prevention of Cell Death by Activation of Hydroxycarboxylic Acid Receptor 1 (GPR81) in Retinal Explants

    Vohra, Rupali, Sanz-Morello, B., Tams, A. L. M., Mouhammad, Zaynab Ahmad, Freude, Kristine, Hannibal, Jens, Aldana, Blanca, Bergersen, L. H. & Kolko, Miriam, 2022, In: Cells. 11, 13, 2098.

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. Published

    Potential metabolic markers in glaucoma and their regulation in response to hypoxia

    Vohra, Rupali, Dalgaard, L. M., Vibaek, J., Langbøl, Mia Aggergaard, Bergersen, L. H., Olsen, N. V., Hassel, B., Chaudhry, F. A. & Kolko, Miriam, 28 Jan 2019, In: Acta Ophthalmologica. 97, 6, p. 567-576

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Published

    Disturbed mitochondrial function restricts glutamate uptake in the human Müller glia cell line, MIO-M1

    Vohra, Rupali, Gurubaran, I. S., Henriksen, U., Bergersen, L. H., Rasmussen, Lene Juel, Desler, C., Jensen, Dorte Skytt & Kolko, Miriam, 2017, In: Mitochondrion. 36, p. 52-59

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. Published

    Dual Properties of Lactate in Müller Cells: The Effect of GPR81 Activation

    Vohra, Rupali, Aldana, Blanca, Waagepetersen, Helle S., Bergersen, L. H. & Kolko, Miriam, 1 Mar 2019, In: Investigative Ophthalmology & Visual Science. 60, 4, p. 999-1008 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    Lactate-Mediated Protection of Retinal Ganglion Cells

    Vohra, Rupali, Aldana, Blanca, Bulli, G., Jensen, Dorte Skytt, Waagepetersen, Helle S., Bergersen, L. H. & Kolko, Miriam, 19 Apr 2019, In: Journal of Molecular Biology. 431, 9, p. 1878-1888 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Published

    A new cellular stress response that triggers centriolar satellite reorganization and ciliogenesis

    Villumsen, B. H., Danielsen, J. R., Povlsen, L., Sylvestersen, K. B., Merdes, A., Beli, P., Yang, Y., Choudhary, Chunaram, Nielsen, Michael Lund, Mailand, Niels & Bekker-Jensen, Simon Holst, 11 Oct 2013, In: E M B O Journal. 32, 23, p. 3029-3040

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. Published

    Local administration of growth hormone stimulates tendon collagen synthesis in elderly men

    Vestergaard, P. E., Jørgensen, J. O. L., Olesen, J., Bosnjak, E., Holm, L., Frystyk, J., Langberg, Henning, Kjær, Michael & Hansen, M. D., Nov 2012, In: Journal of Applied Physiology. 113, 9, p. 1432-8 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. Published

    Inducible Degradation of the Human SMC5/6 Complex Reveals an Essential Role Only during Interphase

    Venegas, A. B., Natsume, T., Kanemaki, M. & Hickson, Ian David, 2020, In: Cell Reports. 31, 3, 20 p., 107533.

    Research output: Contribution to journal › Journal article › Research › peer-review

  40. Published

    Enhancement of Astroglial Aerobic Glycolysis by Extracellular Lactate-Mediated Increase in cAMP

    Vardjan, N., Chowdhury, H. H., Horvat, A., Velebit, J., Malnar, M., Muhič, M., Kreft, M., Krivec, Š. G., Bobnar, S. T., Miš, K., Pirkmajer, S., Offermanns, S., Henriksen, G., Storm-mathisen, J., Bergersen, L. H. & Zorec, R., 2018, In: Frontiers in Molecular Neuroscience. 11, 15 p., 148.

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. Published

    Human derived tendon cells contribute to myotube formation in vitro

    Tsuchiya, Y., Bayer, M. L., Schjerling, Peter, Soendenbroe, C. & Kjær, Michael, 2022, In: Experimental Cell Research. 417, 1, 113164.

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. Published

    Alternative translation initiation generates a functionally distinct isoform of the stress-activated kinase MK2

    Trulley, P., Snieckute, Goda, Bekker-Jensen, D. B., Menon, M. B., Freund, R., Kotlyarov, A., Olsen, Jesper Velgaard, Diaz-Muñoz, M. D., Turner, M., Bekker-Jensen, Simon Holst, Gaestel, M. & Tiedje, C., 2018, bioRxiv, 46 p. (bioRxiv).

    Research output: Working paper › Preprint › Research

  43. Published

    Early development of tendinopathy in humans: Sequence of pathological changes in structure and tissue turnover signaling

    Tran, P. H. T., Malmgaard-Clausen, N. M., Puggaard, R. S., Svensson, R. B., Nybing, J. D., Hansen, P., Schjerling, P., Zinglersen, A. H., Couppé, Christian, Boesen, Mikael Ploug, Magnusson, Stig Peter & Kjær, Michael, 2020, In: FASEB Journal. 34, 1, p. 776-788 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Published

    The influence of fibrillin‐1 and physical activity upon tendon tissue morphology and mechanical properties in mice

    Tran, P. H. T., Skrba, T., Wondimu, E., Galatioto, G., Svensson, R. B., Olesen, A. T., Mackey, Abigail, Magnusson, Stig Peter, Ramirez, F. & Kjær, Michael, 1 Nov 2019, In: Physiological Reports. 7, 21, 9 p., e14267 .

    Research output: Contribution to journal › Journal article › Research › peer-review

  45. Published

    Centriolar satellites: key mediators of centrosome functions

    Tollenaere, M. A. X., Mailand, Niels & Bekker-Jensen, Simon Holst, Jan 2015, In: Cellular and molecular life sciences : CMLS. 73, 1, p. 11-23 13 p.

    Research output: Contribution to journal › Review › Research › peer-review

  46. Published

    p38- and MK2-dependent signalling promotes stress-induced centriolar satellite remodelling via 14-3-3-dependent sequestration of CEP131/AZI1

    Tollenaere, M. A. X., Villumsen, B. H., Blasius, M., Nielsen, J. C., Wagner, S. A., Bartek, J., Beli, P., Mailand, Niels & Bekker-Jensen, Simon Holst, 30 Nov 2015, In: Nature Communications. 6, p. 1-12 12 p., 10075.

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. Published

    ATR Prohibits Replication Catastrophe by Preventing Global Exhaustion of RPA

    Toledo Lazaro, L. I., Altmeyer, M., Rask, M., Lukas, Claudia, Larsen, D. H., Povlsen, L. K., Bekker-Jensen, Simon Holst, Mailand, Niels, Bartek, J. & Lukas, Jiri, 21 Nov 2013, In: Cell. 155, 5, p. 1088-1103 16 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  48. Published

    Oxidative Stress-Induced Dysfunction of Muller Cells During Starvation

    Toft-Kehler, A. K., Gurubaran, I. S., Desler, Claus, Rasmussen, Lene Juel, Jensen, Dorte Skytt & Kolko, Miriam, May 2016, In: Investigative Ophthalmology & Visual Science. 57, 6, p. 2721-2728

    Research output: Contribution to journal › Journal article › Research › peer-review

  49. Published

    Histone H1 couples initiation and amplification of ubiquitin signalling after DNA damage

    Thorslund, T., Ripplinger, A., Hoffmann, Saskia, Wild, T., Uckelmann, M., Villumsen, B., Narita, Takeo, Sixma, T. K., Choudhary, Chunaram, Bekker-Jensen, Simon Holst & Mailand, Niels, 19 Nov 2015, In: Nature. 527, 7578, p. 389-93 5 p.

    Research output: Contribution to journal › Letter › Research › peer-review

  50. Published

    Initial brain aging: heterogeneity of mitochondrial size is associated with decline in complex I-linked respiration in cortex and hippocampus

    Thomsen, Kirsten Joan, Yokota, T., Hasan-Olive, M. M., Sherazi, N., Fakouri, N. B., Desler, Claus, Regnell, C. E., Larsen, S., Rasmussen, Lene Juel, Dela, Flemming, Bergersen, L. H. & Lauritzen, Martin, 2018, In: Neurobiology of Aging. 61, p. 215-224 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

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