Individualized Health

Rev1 deficiency induces a metabolic shift in MEFs that can be manipulated by the NAD⁺ precursor nicotinamide riboside

Anugula, Sharath, Li, Zhiquan, Li, Yuan, Hendriksen, A., Christensen, P. B., Wang, L., Monk, J. M., de Wind, N., Bohr, Vilhelm, Desler, Claus, Naviaux, R. K. & Rasmussen, Lene Juel, 2023, In: Heliyon. 9, 6, e17392.

Research output: Contribution to journal › Journal article › Research › peer-review

Accuracy of a Clinical Applicable Method for Prediction of VO₂max Using Seismocardiography

Hansen, Mikkel Thunestvedt, Husted, Karina Louise Skov, Fogelstrøm, M., Rømer, Tue, Schmidt, S. E., Sørensen, K. & Helge, Jørn Wulff, 2023, In: International Journal of Sports Medicine. 44, 9, p. 650-656

Research output: Contribution to journal › Journal article › Research › peer-review

Altered cardiovascular risk pattern of LDL cholesterol in older adults

Rozing, Maarten Pieter & Westendorp, Rudi GJ, 2023, In: Current Opinion in Lipidology. 34, 1, p. 22-26 5 p.

Research output: Contribution to journal › Review › Research › peer-review

Antioxidant enzymes and Nrf2/Keap1 in human skeletal muscle: Influence of age, sex, adiposity and aerobic fitness

Galvan-Alvarez, V., Gallego-Selles, A., Martinez-Canton, M., García-Gonzalez, E., Gelabert-Rebato, M., Ponce-Gonzalez, J. G., Larsen, Steen, Morales-Alamo, D., Losa-Reyna, J., Perez-Suarez, I., Dorado, C., Perez-Valera, M., Holmberg, H. C., Boushel, R., de Pablos Velasco, P., Helge, Jørn Wulff, Martin-Rincon, M. & Calbet, J. A. L., 2023, In: Free Radical Biology and Medicine. 209, p. 282-291 10 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Cross-species comparison of pregnancy-induced GDF15

Klein, A. B., Ranea-Robles, Pablo, Nicolaisen, T. S., Gil, Cláudia, Johann, K., Prats Quesada, Júlia, Pistoljevic, N., Hviid, K. V. R., Olsen, L. F., Offersen, Simone Margaard, Helge, Jørn Wulff, Nielsen, Henriette Svarre, Bakker, J., Kleinert, Maximilian & Clemmensen, Christoffer, 2023, In: American Journal of Physiology - Endocrinology and Metabolism. 325, 4, p. E303-E309

Research output: Contribution to journal › Journal article › Research › peer-review

Danish Pathology Life Course (PATHOLIFE) cohort: a register based cohort extending upon a national tissue biobank

Yde, Pernille, Bartholdy, Andreas, Gjerdrum, Lise Mette Rahbek, Westendorp, Rudi GJ, Mortensen, Laust Hvas, Bhatt, Samir & Jensen, Majken Karoline, 2023, In: BMJ Open. 13, 4, 10 p., e068483.

Research output: Contribution to journal › Journal article › Research › peer-review

Impact of Aging and Lifelong Exercise Training on Mitochondrial Function and Network Connectivity in Human Skeletal Muscle

Jørgensen, Stine Ringholm, Gudiksen, Anders, Halling, Jens Frey, Qoqaj, A., Rasmussen, P. M., Prats Gavalda, Clara, Plomgaard, Peter Stendahl & Pilegaard, Henriette, 2023, In: Journals of Gerontology. Series A: Biological Sciences & Medical Sciences. 78, 3, 11 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Long-term exposure to air pollution and risk of SARS-CoV-2 infection and COVID-19 hospitalization or death: Danish nationwide cohort study

Zhang, Jiawei, Lim, Youn-Hee, So, Rina, Jørgensen, J. T., Mortensen, Laust Hvas, Napolitano, George, Cole-Hunter, Thomas, Loft, Steffen, Bhatt, Samir, Hoek, G., Brunekreef, B., Westendorp, Rudi GJ, Ketzel, M., Brandt, J., Lange, Theis, Kølsen-Fisher, T. & Andersen, Zorana Jovanovic, 2023, In: The European respiratory journal. 61, 6, 50 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Long-term exposure to elemental components of fine particulate matter and all-natural and cause-specific mortality in a Danish nationwide administrative cohort study

So, R., Chen, J., Stafoggia, M., de Hoogh, K., Katsouyanni, K., Vienneau, D., Samoli, E., Rodopoulou, S., Loft, S., Lim, Y-H., Westendorp, R. G. J., Amini, H., Cole-Hunter, T., Bergmann, M., Shahri, S. M. T., Zhang, J., Maric, M., Mortensen, L. H., Bauwelinck, M., Klompmaker, J. O. & 9 others, Atkinson, R. W., Janssen, N. A. H., Oftedal, B., Renzi, M., Forastiere, F., Strak, M., Brunekreef, B., Hoek, G. & Andersen, Zorana Jovanovic, 2023, In: Environmental Research. 224, 11 p., 115552.

Research output: Contribution to journal › Journal article › Research › peer-review

Predicting mortality and visualizing health care spending by predicted mortality in Danes over age 65

Hansen, A. V., Mortensen, Laust Hvas, Ekstrøm, Claus Thorn, Trompet, S. & Westendorp, Rudi GJ, 2023, In: Scientific Reports. 13, 1, 7 p., 1203.

Research output: Contribution to journal › Journal article › Research › peer-review

A Model for Estimating Biological Age From Physiological Biomarkers of Healthy Aging: Cross-sectional Study

Husted, Karina Louise Skov, Brink-Kjaer, A., Fogelstrom, M., Hulst, P., Bleibach, A., Henneberg, K., Sorensen, H. B. D., Dela, Flemming, Jacobsen, Jens Christian Brings & Helge, Jørn Wulff, 2022, In: JMIR Aging. 5, 2, 15 p., 35696.

Research output: Contribution to journal › Journal article › Research › peer-review

Incorporating Baseline Outcome Data in Individual Participant Data Meta-Analysis of Non-randomized Studies

Syrogiannouli, L., Wildisen, L., Meuwese, C., Bauer, D. C., Cappola, A. R., Gussekloo, J., den Elzen, W. P. J., Trompet, S., Westendorp, R. G. J., Jukema, J. W., Ferrucci, L., Ceresini, G., Åsvold, B. O., Chaker, L., Peeters, R. P., Imaizumi, M., Ohishi, W., Vaes, B., Völzke, H., Sgarbi, J. A. & 7 others, Walsh, J. P., Dullaart, R. P. F., Bakker, S. J. L., Iacoviello, M., Rodondi, N., Del Giovane, C. & for the Thyroid Studies Collaboration, F. T. T. S. C., 2022, In: Frontiers in Psychiatry. 13, 774251.

Research output: Contribution to journal › Journal article › Research › peer-review

Intravenous nicotinamide riboside elevates mouse skeletal muscle NAD⁺ without impacting respiratory capacity or insulin sensitivity

Damgaard, Mads Vargas, Nielsen, Thomas Svava, Basse, A. L., Chubanava, Sabina, Trost, K., Moritz, Thomas, Dellinger, R. W., Larsen, Steen & Treebak, Jonas Thue, 2022, In: iScience. 25, 2, 21 p., 103863.

Research output: Contribution to journal › Journal article › Research › peer-review

Lamin A/C impairments cause mitochondrial dysfunction by attenuating PGC1 and the NAMPT-NAD⁺ pathway

Maynard, S., Hall, A., Galanos, P., Rizza, S., Yamamoto, T., Gram, H. H., Munk, S. H. N., Shoaib, Muhammad, Sørensen, Claus Storgaard, Bohr, Vilhelm, Lerdrup, Mads, Maya-Mendoza, A. & Bartek, J., 2022, In: Nucleic Acids Research. 50, 17, p. 9948-9965 18 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Meeting Report: Aging Research and Drug Discovery

Meron, E., Thaysen, M., Angeli, S., Antebi, A., Barzilai, N., Baur, J. A., Bekker-Jensen, S., Birkisdottir, M., Bischof, E., Bruening, J., Brunet, A., Buchwalter, A., Cabreiro, F., Cai, S., Chen, B. H., Ermolaeva, M., Ewald, C. Y., Ferrucci, L., Florian, M. C., Fortney, K. & 58 others, Freund, A., Georgievskaya, A., Gladyshev, V. N., Glass, D., Golato, T., Gorbunova, V., Hoejimakers, J., Houtkooper, R. H., Jager, S., Jaksch, F., Janssens, G., Jensen, M. B., Kaeberlein, M., Karsenty, G., de Keizer, P., Kennedy, B., Kirkland, J. L., Kjær, Michael, Kroemer, G., Lee, K. F., Lemaitre, J. M., Liaskos, D., Longo, V. D., Lu, Y. X., MacArthur, M. R., Maier, A. B., Manakanatas, C., Mitchell, S. J., Moskalev, A., Niedernhofer, L., Ozerov, I., Partridge, L., Passegué, E., Petr, Michael Angelo, Peyer, J., Radenkovic, D., Rando, T. A., Rattan, S., Riedel, C. G., Rudolph, L., Ai, R., Serrano, M., Schumacher, B., Sinclair, D. A., Smith, R., Suh, Y., Taub, P., Trapp, A., Trendelenburg, A. U., Valenzano, D. R., Verburgh, K., Verdin, E., Vijg, J., Westendorp, Rudi GJ, Zonari, A., Bakula, Daniela Janina, Zhavoronkov, A. & Scheibye-Knudsen, Morten, 2022, In: Aging. 14, 2, p. 530-543 14 p.

Research output: Contribution to journal › Journal article › Research › peer-review

New hallmarks of ageing: a 2022 Copenhagen ageing meeting summary

Schmauck-Medina, T., Molière, A., Lautrup, S., Zhang, J., Chlopicki, S., Madsen, H. B., Cao, S., Soendenbroe, C., Mansell, E., Vestergaard, M. B., Li, Z., Shiloh, Y., Opresko, P. L., Egly, J. M., Kirkwood, T., Verdin, E., Bohr, V. A., Cox, L. S., Stevnsner, T., Rasmussen, L. J. & 1 others, Fang, E. F., 2022, In: Aging. 14, 16, p. 6829-6839 11 p.

Research output: Contribution to journal › Review › Research › peer-review

Subclinical thyroid dysfunction and incident diabetes: a systematic review and an individual participant data analysis of prospective cohort studies

Alwan, H., Villoz, F., Feller, M., Dullaart, R. P. F., Bakker, S. J. L., Peeters, R. P., Kavousi, M., Bauer, D. C., Cappola, A. R., Yeap, B. B., Walsh, J. P., Brown, S. J., Ceresini, G., Ferrucci, L., Gussekloo, J., Trompet, S., Iacoviello, M., Moon, J. H., Razvi, S., Bensenor, I. M. & 11 others, Azizi, F., Amouzegar, A., Valdés, S., Colomo, N., Wareham, N. J., Jukema, J. W., Westendorp, Rudi GJ, Kim, K. W., Rodondi, N., Del Giovane, C. & Thyroid Studies Collaboration, T. S. C., 2022, In: European Journal of Endocrinology. 187, 5, p. S35-S46 12 p.

Research output: Contribution to journal › Review › Research › peer-review

The effect of 8 weeks of physical training on muscle performance and maximal fat oxidation rates in patients treated with simvastatin and coenzyme Q10 supplementation

Kuhlman, A. B., Mikkelsen, L. B., Regnersgaard, S., Heinrichsen, S., Nielsen, F. H., Frandsen, J., Orlando, P., Silvestri, S., Larsen, Steen, Helge, Jørn Wulff & Dela, Flemming, 2022, In: Journal of Physiology. 600, 3, p. 569-581 13 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Thyroid antibodies and levothyroxine effects in subclinical hypothyroidism: A pooled analysis of two randomized controlled trials

Lyko, C., Blum, M. R., Abolhassani, N., Stuber, M. J., Del Giovane, C., Feller, M., Moutzouri, E., Oberle, J., Jungo, K. T., Collet, T-H., den Elzen, W. P. J., Poortvliet, R. K. E., Du Puy, R. S., Dekkers, O. M., Trompet, S., Jukema, J. W., Aujesky, D., Quinn, T., Westendorp, R., Kearney, P. M. & 5 others, Gussekloo, J., Van Heemst, D., Mooijaart, S. P., Bauer, D. C. & Rodondi, N., 2022, In: Journal of Internal Medicine. 292, 6, p. 892-903 12 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Use of candles and risk of cardiovascular and respiratory events in a Danish cohort study

Loft, Steffen, Andersen, Zorana Jovanovic, Jorgensen, J. T., Kristiansen, A. D., Dam, J. K., Cramer, J., Westendorp, Rudi GJ, Lund, Rikke & Lim, Youn-Hee, 2022, In: Indoor Air. 32, 8, 10 p., 13086.

Research output: Contribution to journal › Journal article › Research › peer-review

Reablement through time and space: A scoping review of how the concept of ‘reablement’ for older people has been defined and operationalised

Clotworthy, Amy, Kusumastuti, S. & Westendorp, Rudi GJ, 15 Jan 2021, In: BMC Geriatrics. 21, 16 p., 61.

Research output: Contribution to journal › Journal article › Research › peer-review

Absent Exercise-Induced Improvements in Fat Oxidation in Women With Polycystic Ovary Syndrome After High-Intensity Interval Training

Lionett, S., Kiel, I. A., Røsbjørgen, R., Lydersen, S., Larsen, Steen & Moholdt, T., 2021, In: Frontiers in Physiology. 12, 13 p., 649794.

Research output: Contribution to journal › Journal article › Research › peer-review

Alteration of mitochondrial homeostasis is an early event in a C. elegans model of human tauopathy

Palikaras, K., Achanta, K., Choi, S., Akbari, M. & Bohr, Vilhelm, 2021, In: Aging. 13, 21, p. 23876-23894 19 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Angiotensin-Converting Enzyme 2 (SARS-CoV-2 receptor) expression in human skeletal muscle

Perez-Valera, M., Martinez-Canton, M., Gallego-Selles, A., Galván-Alvarez, V., Gelabert-Rebato, M., Morales-Alamo, D., Santana, A., Martin-Rodriguez, S., Ponce-Gonzalez, J. G., Larsen, S., Losa-Reyna, J., Perez-Suarez, I., Dorado, C., Curtelin, D., Gonzalez-Henriquez, J. J., Boushel, R., Hallen, J., de Pablos Velasco, P., Freixinet-Gilart, J., Holmberg, H. C. & 3 others, Helge, Jørn Wulff, Martin-Rincon, M. & Calbet, J. A. L., 2021, In: Scandinavian Journal of Medicine and Science in Sports. 31, 12, p. 2249-2258 10 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Atorvastatin impairs liver mitochondrial function in obese Göttingen Minipigs but heart and skeletal muscle are not affected

Christiansen, L. B., Dohlmann, T. L., Ludvigsen, T. P., Parfieniuk, E., Ciborowski, M., Szczerbinski, L., Kretowski, A., Desler, Claus, Tiano, L., Orlando, P., Martinussen, Torben, Olsen, Lisbeth Høier & Larsen, Steen, 2021, In: Scientific Reports. 11, 15 p., 2167.

Research output: Contribution to journal › Journal article › Research › peer-review

Base excision repair causes age-dependent accumulation of single-stranded DNA breaks that contribute to Parkinson disease pathology

SenGupta, T., Palikaras, K., Esbensen, Y. Q., Konstantinidis, G., Galindo, F. J. N., Achanta, K., Kassahun, H., Stavgiannoudaki, I., Bohr, Vilhelm, Akbari, M., Gaare, J., Tzoulis, C., Tavernarakis, N. & Nilsen, H., 2021, In: Cell Reports. 36, 10, 109668.

Research output: Contribution to journal › Journal article › Research › peer-review

CDK2 phosphorylation of Werner protein (WRN) contributes to WRN’s DNA double-strand break repair pathway choice

Lee, J. H., Shamanna, R. A., Kulikowicz, T., Fakouri, N. B., Kim, E. W., Christiansen, L. S., Croteau, D. L. & Bohr, Vilhelm, 2021, In: Aging Cell. 20, 11, 14 p., e13484.

Research output: Contribution to journal › Journal article › Research › peer-review

Cytosolic self-DNA—A potential source of chronic inflammation in aging

Akbari, M., Shanley, D. P., Bohr, Vilhelm & Rasmussen, Lene Juel, 2021, In: Cells. 10, 12, 3544.

Research output: Contribution to journal › Review › Research › peer-review

Depleted myocardial coenzyme Q10 in cavalier king charles spaniels with congestive heart failure due to myxomatous mitral valve disease

Christiansen, L. B., Reimann, Maria Josefine, Schou-Pedersen, A. M. V., Larsen, Steen, Lykkesfeldt, Jens & Olsen, Lisbeth Høier, 2021, In: Antioxidants. 10, 2, p. 1-13 13 p., 161.

Research output: Contribution to journal › Journal article › Research › peer-review

EX-vivo whole blood stimulation with A2E does not elicit an inflammatory cytokine response in patients with age-related macular degeneration

Durhuus, J. A., Rozing, Maarten Pieter, Nielsen, M. K., Molbech, C. R., Keijzers, G., Scheibye-Knudsen, Morten, Rasmussen, Lene Juel, Westendorp, Rudi GJ & Sørensen, Torben Lykke, 2021, In: Scientific Reports. 11, 1, 8226.

Research output: Contribution to journal › Journal article › Research › peer-review

Effect of Levothyroxine Therapy on the Development of Depressive Symptoms in Older Adults With Subclinical Hypothyroidism An Ancillary Study of a Randomized Clinical Trial

Wildisen, L., Feller, M., Del Giovane, C., Moutzouri, E., Du Puy, R. S., Mooijaart, S. P., Collet, T., Poortvliet, R. K. E., Kearney, P., Quinn, T. J., Kloppel, S., Bauer, D. C., Peeters, R. P., Westendorp, Rudi GJ, Aujesky, D., Gussekloo, J. & Rodondi, N., 2021, In: JAMA network open. 4, 2, 12 p., 2036645.

Research output: Contribution to journal › Journal article › Research › peer-review

Effects of football fitness training on lymphedema and upper-extremity function in women after treatment for breast cancer: A randomized trial

Bloomquist, K., Krustrup, P., Fristrup, B., Sørensen, V., Helge, Jørn Wulff, Helge, Eva Wulff, Soelberg Vadstrup, E., Rørth, M., Hayes, S. C. & Uth, J., 2021, In: Acta Oncologica. 60, 3, p. 392-400 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Endotrophin is associated with chronic multimorbidity and all-cause mortality in a cohort of elderly women

Staunstrup, L. M., Bager, C. L., Frederiksen, P., Helge, Jørn Wulff, Brunak, Søren, Christiansen, C. & Karsdal, M., 2021, In: EBioMedicine. 68, 10 p., 103391.

Research output: Contribution to journal › Journal article › Research › peer-review

Familial longevity is associated with lower baseline bone turnover but not differences in bone turnover in response to rhTSH

Zutinic, A., Roelfsema, F., Pijl, H., Ballieux, B. E., Westendorp, Rudi GJ, Blauw, G. J. & van Heemst, D., 2021, In: Aging. 13, 17, p. 21029-21039 11 p.

Research output: Contribution to journal › Journal article › Research › peer-review

High bone mineral density in lifelong trained female team handball players and young elite football players

Hagman, M., Helge, Eva Wulff, Fristrup, B., Jørgensen, Niklas Rye, Helge, Jørn Wulff & Krustrup, P., 2021, In: European Journal of Applied Physiology. 121, 10, p. 2825-2836 12 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Maximal fat oxidation rate is higher in fit women and unfit women with obesity, compared to normal weight unfit women

Frandsen, J., Hansen, I. M. D., Wismann, J. F., Olsen, M. H., Brage-Andersen, M. R., Sahl, Ronni Eg, Hansen, M., Ingersen, Arthur, Modvig, J. L., Schmücker, M., brl298, brl298, Dela, Flemming, Larsen, Steen & Helge, Jørn Wulff, 2021, In: Journal of Clinical Endocrinology and Metabolism. 106, 11, p. E4389-E4399 11 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Metabolomic Profile of Skeletal Muscle and Its Change Under a Mixed-Mode Exercise Intervention in Progressively Dysglycemic Subjects

Szczerbinski, L., Golonko, A., Taylor, M., Puchta, U., Konopka, P., Paszko, A., Citko, A., Szczerbinski, K., Gorska, M., Zabielski, P., Błachnio-Zabielska, A., Larsen, Steen & Kretowski, A., 2021, In: Frontiers in Endocrinology. 12, 13 p., 778442.

Research output: Contribution to journal › Journal article › Research › peer-review

NAD+ supplementation reduces neuroinflammation and cell senescence in a transgenic mouse model of Alzheimer's disease via cGAS-STING

Hou, Y., Wei, Y., Lautrup, S., Yang, B., Wang, Y., Cordonnier, S., Mattson, M. P., Croteau, D. L. & Bohr, Vilhelm, 2021, In: Proceedings of the National Academy of Sciences of the United States of America. 118, 37, e2011226118.

Research output: Contribution to journal › Journal article › Research › peer-review

Olfactory dysfunction in aging and neurodegenerative diseases

Dan, X., Wechter, N., Gray, S., Mohanty, J. G., Croteau, D. L. & Bohr, Vilhelm, 2021, In: Ageing Research Reviews. 70, 101416.

Research output: Contribution to journal › Review › Research › peer-review

One year of Football Fitness improves L1-L4 BMD, postural balance and muscle strength in women treated for breast cancer

Uth, J., Fristrup, B., Sørensen, V., Helge, Eva Wulff, Christensen, M. K., Kjærgaard, J. B., Møller, T. K., Helge, Jørn Wulff, Jørgensen, Niklas Rye, Rørth, M., Vadstrup, E. S. & Krustrup, P., 2021, In: Scandinavian Journal of Medicine & Science in Sports. 31, 7, p. 1545-1557 13 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Peak fat oxidation rate is closely associated with plasma free fatty acid concentrations in women; similar to men

Frandsen, J., Poggi, A. I., Ritz, C., Larsen, S., Dela, Flemming & Helge, Jørn Wulff, 2021, In: Frontiers in Physiology. 12, 11 p., 696261.

Research output: Contribution to journal › Journal article › Research › peer-review

Pharmacological but not physiological GDF15 suppresses feeding and the motivation to exercise

Klein, A. B., Nicolaisen, T. S., Ørtenblad, N., Gejl, K. D., Jensen, R., Fritzen, A. M., Larsen, E. L., Karstoft, K., Poulsen, H. E., Morville, T., Sahl, R. E., Helge, J. W., Lund, J., Falk, S., Lyngbæk, M., Ellingsgaard, H., Pedersen, B. K., Lu, W., Finan, B., Jørgensen, S. B. & 5 others, Seeley, R. J., Kleinert, Maximilian, Kiens, Bente, Richter, Erik A. & Clemmensen, Christoffer, 2021, In: Nature Communications. 12, 9 p., 1041.

Research output: Contribution to journal › Journal article › Research › peer-review

Reliability and variation in mitochondrial respiration in human adipose tissue

Sahl, Ronni Eg, Høy Helms, E. F., Schmücker, Malte, Flensted-Jensen, Mathias, Ingersen, Arthur, Morville, T., Dela, Flemming, Helge, Jørn Wulff & Larsen, S., 2021, In: Adipocytes. 10, 1, p. 605-611 7 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Six weeks of high intensity cycle training reduces H2O2 emission and increases antioxidant protein levels in obese adults with risk factors for type 2 diabetes

Flensted-Jensen, Mathias, Gram, M., Dela, Flemming, Helge, Jørn Wulff & Larsen, Steen, 2021, In: Free Radical Biology & Medicine. 173, p. 1-6

Research output: Contribution to journal › Journal article › Research › peer-review

The effects of 3 weeks of oral glutathione supplementation on whole body insulin sensitivity in obese males with and without type 2 diabetes: a randomized trial

Søndergård, S. D., Cintin, I., Kuhlman, A. B., Morville, T. H., Bergmann, M. L., Kjær, L. K., Poulsen, Henrik Enghusen, Giustarini, D., Rossi, R., Dela, Flemming, Helge, Jørn Wulff & Larsen, S., 2021, In: Applied Physiology, Nutrition and Metabolism. 46, 9, 10 p.

Research output: Contribution to journal › Journal article › Research › peer-review

The influence of age, sex and cardiorespiratory fitness on maximal fat oxidation rate

Frandsen, J., Amaro-Gahete, F. J., Landgrebe, A., Dela, Flemming, Ruiz, J. R., Helge, Jørn Wulff & Larsen, Steen, 2021, In: Applied Physiology, Nutrition and Metabolism. 46, 10, p. 1241-1247

Research output: Contribution to journal › Journal article › Research › peer-review

The response of mitochondrial respiration and quantity in skeletal muscle and adipose tissue to exercise in humans with prediabetes

Szczerbinski, L., Taylor, M. A., Puchta, U., Konopka, P., Paszko, A., Citko, A., Szczerbinski, K., Goscik, J., Gorska, M., Larsen, Steen & Kretowski, A., 2021, In: Cells. 10, 11, 3013.

Research output: Contribution to journal › Journal article › Research › peer-review

The training induced increase in whole-body peak fat oxidation rate may be attenuated with aging

Frandsen, J., Beck, T., Langkilde, C. H., Larsen, Steen, Dela, Flemming & Helge, Jørn Wulff, 2021, In: European Journal of Sport Science. 21, 1, p. 69-76

Research output: Contribution to journal › Journal article › Research › peer-review

Tipping Points-Do the Prognostic Values of Multimorbidity and Functional Status Vary with Age?

Thygesen, L. C., Christensen, K., Rorth, M., Sørensen, H. T., Vandenbroucke, J. P. & Westendorp, Rudi GJ, 2021, In: Clinical Epidemiology. 13, p. 853-857 5 p.

Research output: Contribution to journal › Editorial › Research › peer-review

Validity and reliability of a clinical non-exercise method for assessment of cardiorespiratory fitness using seismocardiography

Hansen, Mikkel Thunestvedt, Rømer, Tue, Hoejgaard, A., Husted, Karina Louise Skov, Soerensen, K., Schmidt, S., Dela, Flemming & Helge, Jørn Wulff, 2021, In: European Heart Journal. 42, Suppl. 1, p. 3172-3172

Research output: Contribution to journal › Conference abstract in journal › Research

Cockayne syndrome proteins CSA and CSB maintain mitochondrial homeostasis through NAD+ signaling

Okur, M. N., Fang, E. F., Fivenson, E. M., Tiwari, V., Croteau, D. L. & Bohr, Vilhelm, Dec 2020, In: Aging Cell. 19, 12, p. e13268

Research output: Contribution to journal › Journal article › Research › peer-review

Risky business: How older ‘at risk’ people in Denmark evaluated their situated risk during the COVID-19 pandemic

Clotworthy, Amy & Westendorp, Rudi GJ, Dec 2020, In: Anthropology & Aging. 41, 2, p. 167-176 10 p.

Research output: Contribution to journal › Journal article › Research › peer-review

ETNK1 Mutations in Atypical Chronic Myeloid Leukemia Induce a Mutator Phenotype That Can be Reverted with Phosphoethanolamine

Fontana, D., Mauri, M., Renso, R., Docci, M., Crespiatico, I., Rost, L. M., Jang, M., Niro, A., D'Aliberti, D., Massimino, L., Bertagna, M., Zambrotta, G., Bossi, M., Citterio, S., Crescenzi, B., Fanelli, F., Cassina, V., Corti, R., Salerno, D., Nardo, L. & 10 others, Chinello, C., Mantegazza, F., Mecucci, C., Magni, F., Cavaletti, G., Bruheim, P., Rea, D., Larsen, Steen, Piazza, R. & Gambacorti-Passerini, C., Nov 2020, In: Blood. 136, Suppl. 2, 3 p., LBA-5.

Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

The effectiveness of body age-based intervention in workplace health promotion: Results of a cohort study on 9851 Danish employees

Husted, Karina Louise Skov, Dandanell, S., Petersen, Janne, Dela, Flemming & Helge, Jørn Wulff, Sep 2020, In: PLoS ONE. 15, 9 September, 14 p., e0239337.

Research output: Contribution to journal › Journal article › Research › peer-review

Center for Sund Aldring: Regeringen overser ældres ret til selvbestemmelse

Clotworthy, Amy & Westendorp, Rudi GJ, 19 May 2020, In: Altinget.dk. 1 p.

Research output: Contribution to journal › Contribution to newspaper - Newspaper article › Communication

Cockayne syndrome group A and B proteins function in rRNA transcription through nucleolin regulation

Okur, M. N., Lee, J., Osmani, W., Kimura, R., Demarest, T. G., Croteau, D. L. & Bohr, Vilhelm, 18 Mar 2020, In: Nucleic Acids Research. 48, 5, p. 2473-2485 13 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Dietary habits, metabolic health and vitamin D status in Greenlandic children

Courraud, J., Quist, Jonas Salling, Kontopodi, E., Blomberg Jensen, M., Bjerrum, P. J., Helge, Jørn Wulff & Sørensen, K., 1 Jan 2020, In: Public Health Nutrition. 23, 5, p. 904-913

Research output: Contribution to journal › Journal article › Research › peer-review

Short-term NAD+ supplementation prevents hearing loss in mouse models of Cockayne syndrome

Okur, M. N., Mao, B., Kimura, R., Haraczy, S., Fitzgerald, T., Edwards-Hollingsworth, K., Tian, J., Osmani, W., Croteau, D. L., Kelley, M. W. & Bohr, Vilhelm, Jan 2020, In: npj Aging and Mechanisms of Disease. 6, 10 p., 1.

Research output: Contribution to journal › Journal article › Research › peer-review

A Biological Age Model Designed for Health Promotion Interventions: Protocol for an Interdisciplinary Study for Model Development

Husted, Karina Louise Skov, Fogelstrom, M., Hulst, P., Brink-Kjaer, A., Henneberg, K., Sorensen, H. B. D., Dela, Flemming & Helge, Jørn Wulff, 2020, In: JMIR Research Protocols. 9, 10, 13 p., 19209.

Research output: Contribution to journal › Journal article › Research › peer-review

Acetaminophen toxicity induces mitochondrial complex I inhibition in human liver tissue

Chrøis, K. M., Larsen, Steen, Pedersen, J. S., Rygg, M. O., Boilsen, A. E. B., Bendtsen, Flemming & Dela, Flemming, 2020, In: Basic & Clinical Pharmacology & Toxicology. 126, 1, p. 86-91

Research output: Contribution to journal › Journal article › Research › peer-review

Age-related macular degeneration: A two-level model hypothesis

Rozing, Maarten Pieter, Durhuus, J. A., Krogh Nielsen, M., Subhi, Y., Kirkwood, T. B. L., Westendorp, Rudi GJ & Sørensen, Torben Lykke, 2020, In: Progress in Retinal and Eye Research. 76, 100825.

Research output: Contribution to journal › Journal article › Research › peer-review

An analysis of the productivity and impact of clinical PhD theses from the University of Copenhagen

Rømer, Tue, Hansen, Mikkel Thunestvedt & Helge, Jørn Wulff, 2020, In: Danish Medical Journal. 67, 5, A12190731.

Research output: Contribution to journal › Journal article › Research › peer-review

An individual participant data analysis of prospective cohort studies on the association between subclinical thyroid dysfunction and depressive symptoms

Wildisen, L., Del Giovane, C., Moutzouri, E., Beglinger, S., Syrogiannouli, L., Collet, T-H., Cappola, A. R., Asvold, B. O., Bakker, S. J. L., Yeap, B. B., Almeida, O. P., Ceresini, G., Dullaart, R. P. F., Ferrucci, L., Grabe, H., Jukema, J. W., Nauck, M., Trompet, S., Voelzke, H., Westendorp, R. & 7 others, Gussekloo, J., Kloppel, S., Aujesky, D., Bauer, D., Peeters, R., Feller, M. & Rodondi, N., 2020, In: Scientific Reports. 10, 1, 12 p., 19111.

Research output: Contribution to journal › Journal article › Research › peer-review

Beta-aminoisobutyric acid is released by contracting human skeletal muscle and lowers insulin release from INS-1 832/3 cells by mediating mitochondrial energy metabolism

Barlow, J. P., Karstoft, K., Vigelsø, A., Gram, M., Helge, Jørn Wulff, Dela, Flemming, Pappan, K., O'Neil, D., Dunn, W. & Solomon, T. P. J., 2020, In: Metabolism open. 7, p. 100053

Research output: Contribution to journal › Journal article › Research › peer-review

Cardioprotective effect of succinate dehydrogenase inhibition in rat hearts and human myocardium with and without diabetes mellitus

Jespersen, N. R., Hjortbak, M. V., Lassen, T. R., Støttrup, N. B., Johnsen, J., Tonnesen, P. T., Larsen, Steen, Kimose, H. H. & Bøtker, H. E., 2020, In: Scientific Reports. 10, 1, 15 p., 10344.

Research output: Contribution to journal › Journal article › Research › peer-review

Cardiovascular and metabolic health effects of team handball training in overweight women: Impact of prior experience

Hornstrup, T., Póvoas, S., Helge, Jørn Wulff, Melcher, Pia Grethe Sandfeld, Fristrup, B., Andersen, J. L., Møgelvang, R., Hansen, Peter Riis, Nybo, Lars & Krustrup, P., 2020, In: Scandinavian Journal of Medicine & Science in Sports. 30, 2, p. 281-294 14 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Cellular senescence and chronological age in various human tissues: A systematic review and meta-analysis

Tuttle, C. S. L., Waaijer, M. E. C., Slee-Valentijn, M. S., Stijnen, T., Westendorp, Rudi GJ & Maier, A. B., 2020, In: Aging Cell. 19, 2, 11 p., e13083.

Research output: Contribution to journal › Review › Research › peer-review

Circulating Thyroid Hormone Profile in Response to a Triiodothyronine Challenge in Familial Longevity

Zutinic, A., Blauw, G. J., Pijl, H., Ballieux, B. E., Westendorp, Rudi GJ, Roelfsema, F. & van Heemst, D., 2020, In: Endocrine Research. 4, 10, 9 p., bvaa117.

Research output: Contribution to journal › Journal article › Research › peer-review

DNA damage invokes mitophagy through a pathway involving Spata18

Dan, X., Babbar, M., Moore, A., Wechter, N., Tian, J., Mohanty, J. G., Croteau, D. L. & Bohr, Vilhelm, 2020, In: Nucleic Acids Research. 48, 12, p. 6611-6623 13 p.

Research output: Contribution to journal › Journal article › Research › peer-review

ETNK1 mutations induce a mutator phenotype that can be reverted with phosphoethanolamine

Fontana, D., Mauri, M., Renso, R., Docci, M., Crespiatico, I., Røst, L. M., Jang, M., Niro, A., D’aliberti, D., Massimino, L., Bertagna, M., Zambrotta, G., Bossi, M., Citterio, S., Crescenzi, B., Fanelli, F., Cassina, V., Corti, R., Salerno, D., Nardo, L. & 10 others, Chinello, C., Mantegazza, F., Mecucci, C., Magni, F., Cavaletti, G., Bruheim, P., Rea, D., Larsen, Steen, Gambacorti-passerini, C. & Piazza, R., 2020, In: Nature Communications. 11, 1, 16 p., 5938.

Research output: Contribution to journal › Journal article › Research › peer-review

Effect of Thyroid Hormone Therapy on Fatigability in Older Adults with Subclinical Hypothyroidism: A Nested Study within a Randomized Placebo-Controlled Trial

Stuber, M. J., Moutzouri, E., Feller, M., Del Giovane, C., Bauer, D. C., Blum, M. R., Collet, T. H., Gussekloo, J., Mooijaart, S. P., McCarthy, V. J. C., Aujesky, D., Westendorp, Rudi GJ, Stott, D. J., Glynn, N. W., Kearney, P. M., Rodondi, N. & Newman, A., 2020, In: Journals of Gerontology - Series A Biological Sciences and Medical Sciences. 75, 9, p. e89-e94 6 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Effects of small-sided recreational team handball training on mechanical muscle function, body composition and bone mineralization in untrained young adults - A randomized controlled trial

Fristrup, B., Krustrup, P., Andersen, J. L., Hornstrup, T., Løwenstein, F. T., Larsen, M. A., Helge, Jørn Wulff, Póvoas, S. C. A. & Aagaard, P., 2020, In: P L o S One. 15, 11, 17 p., e0241359.

Research output: Contribution to journal › Journal article › Research › peer-review

Exercise intensity and cardiovascular health outcomes after 12 months of football fitness training in women treated for stage I-III breast cancer: Results from the football fitness After Breast Cancer (ABC) randomized controlled trial

Uth, J., Fristrup, B., Sørensen, V., Helge, Eva Wulff, Christensen, M. K., Kjærgaard, J. B., Møller, T. K. T., Mohr, M., Helge, Jørn Wulff, Jørgensen, Niklas Rye, Rørth, M., Vadstrup, E. S. & Krustrup, P., 2020, In: Progress in Cardiovascular Diseases. 63, 6, p. 792-799 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Exercise training results in depot-specific adaptations to adipose tissue mitochondrial function

Mendham, A. E., Larsen, Steen, George, C., Adams, K., Hauksson, J., Olsson, T., Fortuin-de Smidt, M. C., Nankam, P. A. N., Hakim, O., Goff, L. M., Pheiffer, C. & Goedecke, J. H., 2020, In: Scientific Reports. 10, 1, 14 p., 3785.

Research output: Contribution to journal › Journal article › Research › peer-review

Frailty Index Status of Canadian Home Care Clients Improves With Exercise Therapy and Declines in the Presence of Polypharmacy

Larsen, R. T., Turcotte, L. A., Westendorp, Rudi GJ, Langberg, Henning & Hirdes, J. P., 2020, In: Journal of the American Medical Directors Association. 21, 6, p. 766-771 6 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Heterochromatin: an epigenetic point of view in aging

Lee, J., Kim, E. W., Croteau, D. L. & Bohr, Vilhelm, 2020, In: Experimental & Molecular Medicine. 52, 9, p. 1466-1474 9 p.

Research output: Contribution to journal › Review › Research › peer-review

Hippocampal tau oligomerization early in tau pathology coincides with a transient alteration of mitochondrial homeostasis and DNA repair in a mouse model of tauopathy

Zheng, Jin, Akbari, M., Schirmer, C., Reynaert, M. L., Loyens, A., Lefebvre, B., Buée, L., Croteau, D. L., Galas, M. C. & Bohr, Vilhelm, 2020, In: Acta Neuropathologica Communications. 8, 1, 23 p., 25.

Research output: Contribution to journal › Journal article › Research › peer-review

Interaction between RECQL4 and OGG1 promotes repair of oxidative base lesion 8-oxoG and is regulated by SIRT1 deacetylase

Duan, S., Han, X., Akbari, M., Croteau, D. L., Rasmussen, Lene Juel & Bohr, Vilhelm, 2020, In: Nucleic Acids Research. 48, 12, p. 6530–6546

Research output: Contribution to journal › Journal article › Research › peer-review

Interrelationships Between Pituitary Hormones as Assessed From 24-hour Serum Concentrations in Healthy Older Subjects

van der Spoel, E., Roelfsema, F., Akintola, A. A., Jansen, S. W., Slagboom, P. E., Westendorp, Rudi GJ, Blauw, G. J., Pijl, H. & van Heemst, D., 2020, In: Journal of Clinical Endocrinology & Metabolism. 105, 4, p. e1201–e1214 4 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Long-term exposure to air pollution and stroke incidence: A Danish Nurse cohort study

Amini, H., Dehlendorff, C., Lim, Y-H., Mehta, A., Jørgensen, J. T., Mortensen, L. H., Westendorp, R., Hoffmann, B., Loft, S., Cole-Hunter, T., Bräuner, E. V., Ketzel, M., Hertel, O., Brandt, J., Solvang Jensen, S., Christensen, J. H., Geels, C., Frohn, L. M., Backalarz, C., Simonsen, M. K. & 1 others, Andersen, Zorana Jovanovic, 2020, In: Environment International. 142, 8 p., 105891.

Research output: Contribution to journal › Journal article › Research › peer-review

Low-Grade Inflammation Is Not Present in Former Obese Males but Adipose Tissue Macrophage Infiltration Persists

Ara, I., Auerbach, P., Larsen, Steen, Mata, E., Stallknecht, Bente Merete, Ploug, Thorkil, Prats Gavalda, Clara & Helge, Jørn Wulff, 2020, In: Biomedicines. 8, 5, 10 p., 123.

Research output: Contribution to journal › Journal article › Research › peer-review

Men Have a Stronger Monocyte-Derived Cytokine Production Response upon Stimulation with the Gram-Negative Stimulus Lipopolysaccharide than Women: A Pooled Analysis Including 15 Study Populations

Beenakker, K. G. M., Westendorp, Rudi GJ, de Craen, A. J. M., Chen, S., Raz, Y., Ballieux, B. E. P. B., Nelissen, R. G. H. H., Later, A. F. L., Huizinga, T. W., Slagboom, P. E., Boomsma, D. I. & Maier, A. B., 2020, In: Journal of Innate Immunity. 12, p. 142-153 12 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Menstrual cycle phase does not affect whole body peak fat oxidation rate during a graded exercise test

Frandsen, J., Pistoljevic, N., Quesada, J. P., Amaro-Gahete, F. J., Ritz, C., Larsen, S., Dela, Flemming & Helge, Jørn Wulff, 2020, In: Journal of Applied Physiology. 128, 3, p. 681-687 7 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Mitochondrial adaptations to high intensity interval training in older females and males

Chrois, K. M., Dohlmann, T. L., Sogaard, D., Hansen, Camilla Collin, Dela, Flemming, Helge, Jørn Wulff & Larsen, Steen, 2020, In: European Journal of Sport Science. 20, 1, p. 135-145

Research output: Contribution to journal › Journal article › Research › peer-review

Mitochondrial dysfunction in adults after out-of-hospital cardiac arrest

Wiberg, S., Stride, N., Bro-Jeppesen, J., Holmberg, M. J., Kjærgaard, J., Larsen, Steen, Donnino, M. W., Hassager, Christian & Dela, Flemming, 2020, In: European Heart Journal: Acute Cardiovascular Care. 9, 4, p. S138–S144 7 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Onset of Workplace Bullying and Risk of Weight Gain: A Multicohort Longitudinal Study

Xu, Tianwei, Magnusson Hanson, L. L., Clark, A. J., Ersbøll, A. K., Westerlund, H., Madsen, I. E. H., Rugulies, Reiner Ernst, Pentti, J., Stenholm, S., Vahtera, J., Sørensen, J. K., Nordentoft, M., Westendorp, Rudi GJ, Hansen, Åse Marie, Oksanen, T., Virtanen, M., Kivimäki, M. & Rod, Naja Hulvej, 2020, In: Obesity. 28, 11, p. 2216-2223 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Perceived stress and dementia: Results from the Copenhagen city heart study

Nabe-Nielsen, Kirsten, Rod, Naja Hulvej, Hansen, Åse Marie, Prescott, Eva, Grynderup, M. B., Islamoska, S., Ishtiak-Ahmed, K., Garde, Anne Helene, Gyntelberg, F., Mortensen, Erik Lykke, Thien Kieu Thi Phung, Waldemar, Gunhild & Westendorp, Rudi GJ, 2020, In: Aging & Mental Health. 24, 11, p. 1828-1836 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Plasma Metabolome Profiling of Resistance Exercise and Endurance Exercise in Humans

Morville, T., Sahl, Ronni Eg, Moritz, Thomas, Helge, Jørn Wulff & Clemmensen, Christoffer, 2020, In: Cell Reports. 33, 13, 14 p., 108554.

Research output: Contribution to journal › Journal article › Research › peer-review

Reply to Dutheil et al

Frandsen, J., Pistoljevic, N., Quesada, J. P., Amaro-Gahete, F. J., Larsen, Steen, Dela, Flemming & Helge, Jørn Wulff, 2020, In: Journal of applied physiology (Bethesda, Md. : 1985). 129, 1, 1 p.

Research output: Contribution to journal › Comment/debate › Research › peer-review

Shift work and incidence of dementia: A Danish Nurse Cohort study

Jørgensen, J. T., Hansen, J., Westendorp, Rudi GJ, Nabe-Nielsen, Kirsten, Stayner, L. T., Simonsen, M. K. & Andersen, Zorana Jovanovic, 2020, In: Alzheimer's and Dementia. 16, 9, p. 1268-1279 12 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Simvastatin improves mitochondrial respiration in peripheral blood cells

Durhuus, J. A., Hansson, Svenja, Morville, T., Kuhlman, A. B., Dohlmann, T. L., Larsen, Steen, Helge, Jørn Wulff, Angleys, M., Muniesa-Vargas, A., Bundgaard, J. R., Hickson, Ian David, Dela, Flemming, Desler, Claus & Rasmussen, Lene Juel, 2020, In: Scientific Reports. 10, 1, 17012.

Research output: Contribution to journal › Journal article › Research › peer-review

Skeletal Effects of Levothyroxine for Subclinical Hypothyroidism in Older Adults: A TRUST Randomized Trial Nested Study

Gonzalez Rodriguez, E., Stuber, M., Del Giovane, C., Feller, M., Collet, T. H., Löwe, A. L., Blum, M. R., van Vliet, N. A., van Heemst, D., Kearney, P. M., Gussekloo, J., Mooijaart, S., Westendorp, Rudi GJ, Stott, D. J., Aeberli, D., Bauer, D. C., Hans, D. & Rodondi, N., 2020, In: The Journal of clinical endocrinology and metabolism. 105, 1, p. 336–343 8 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Spatial Transcriptomics Reveals Genes Associated with Dysregulated Mitochondrial Functions and Stress Signaling in Alzheimer Disease

Navarro, J. F., Croteau, D. L., Jurek, A., Andrusivova, Z., Yang, B., Wang, Y., Ogedegbe, B., Riaz, T., Støen, M., Desler, Claus, Rasmussen, Lene Juel, Tønjum, T., Galas, M. C., Lundeberg, J. & Bohr, Vilhelm, 2020, In: iScience. 23, 10, 42 p., 101556.

Research output: Contribution to journal › Journal article › Research › peer-review

The NAD⁺-mitophagy axis in healthy longevity and in artificial intelligence-based clinical applications

Aman, Y., Frank, J., Lautrup, S. H., Matysek, A., Niu, Z., Yang, G., Shi, L., Bergersen, L. H., Storm-Mathisen, J., Rasmussen, Lene Juel, Bohr, Vilhelm, Nilsen, H. & Fang, E. F., 2020, In: Mechanisms of Ageing and Development. 185, 111194.

Research output: Contribution to journal › Journal article › Research › peer-review

The relationship between peak fat oxidation and prolonged double-poling endurance exercise performance

Rømer, Tue, Hansen, Mikkel Thunestvedt, Frandsen, J., Larsen, Steen, Dela, Flemming & Helge, Jørn Wulff, 2020, In: Scandinavian Journal of Medicine & Science in Sports. 30, 11, p. 2044-2056

Research output: Contribution to journal › Journal article › Research › peer-review

Thyroid hormone receptor α in skeletal muscle is essential for T3-mediated increase in energy expenditure

Nicolaisen, T. S., Klein, A. B., Dmytriyeva, O., Lund, Jens, Ingerslev, L. R., Fritzen, Andreas Mæchel, Carl, Christian Strini, Lundsgaard, Anne-Marie, Frost, M., Ma, Tao, Schjerling, P., Gerhart-Hines, Zach, Flamant, F., Gauthier, K., Larsen, Steen, Richter, Erik A., Kiens, Bente & Clemmensen, Christoffer, 2020, In: F A S E B Journal. 34, 11, p. 15480-15491 12 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Towards Inclusive Healthcare Delivery: Potentials and Challenges of Human-Centred Design in Health Innovation Processes to Increase Healthy Aging

Sandholdt, Catharina Thiel, Cunningham, J., Westendorp, Rudi GJ & Kristiansen, Maria, 2020, In: International Journal of Environmental Research and Public Health. 17, 12, 9 p., 4551.

Research output: Contribution to journal › Journal article › Research › peer-review

Gaan we luisteren of meten?

Westendorp, Rudi GJ & Kusumastuti, S., 18 Nov 2019, In: Nederlands Tijdschrift voor Geneeskunde. 163, D4473.

Research output: Contribution to journal › Comment/debate › Research

Statin Treatment Decreases Mitochondrial Respiration But Muscle Coenzyme Q10 Levels Are Unaltered: The LIFESTAT Study

Dohlmann, T. L., Morville, T., Kuhlman, A. B., Chrøis, K. M., Helge, Jørn Wulff, Dela, Flemming & Larsen, Steen, Jul 2019, In: Journal of Clinical Endocrinology and Metabolism. 104, 7, p. 2501–2508

Research output: Contribution to journal › Journal article › Research › peer-review

Effects of Long-Term Physical Activity and Diet on Skin Glycation and Achilles Tendon Structure

Hjerrild, J. N., Wobbe, A., Stausholm, M. B., Larsen, A. E., Josefsen, C. O., Malmgaard-Clausen, N. M., Dela, Flemming, Kjær, Michael, Magnusson, Stig Peter, Hansen, M., Svensson, R. B. & Couppé, C., 22 Jun 2019, In: Nutrients. 11, 6

Research output: Contribution to journal › Journal article › Research › peer-review

GIP-induced vasodilation in human adipose tissue involves capillary recruitment

Asmar, M., Asmar, A., Simonsen, L., Dela, Flemming, Holst, Jens Juul & Bulow, J., Jun 2019, In: Endocrine Connections. 8, 6, p. 806-813

Research output: Contribution to journal › Journal article › Research › peer-review

ADAMTS9 regulates skeletal muscle insulin sensitivity through extracellular matrix alterations

Graae, A-S., Grarup, N., Ribel-Madsen, R., Lystbæk, S. H., Boesgaard, T., Staiger, H., Fritsche, A., Wellner, N., Sulek, K., Kjølby, M. F., Backe, M. B., Chubanava, S., Prats, C., Serup, A. K. L., Birk, J. B., Dubail, J., Gillberg, L., Vienberg, S. G., Nykjær, A., Kiens, B. & 10 others, Wojtaszewski, Jørgen F P, Larsen, Steen, Apte, S. S., Häring, H., Vaag, A., Zethelius, B., Pedersen, Oluf Borbye, Treebak, Jonas Thue, Hansen, Torben & Holst, Birgitte, 2019, In: Diabetes. 68, 3, p. 502-514

Research output: Contribution to journal › Journal article › Research › peer-review

Aerobic Exercise Performance and Muscle Strength in Statin Users-The LIFESTAT Study

Morville, T., Dohlmann, T. L., Kuhlman, A. B., Sahl, Ronni Eg, Kriegbaum, Margit, Larsen, Steen, Dela, Flemming & Helge, Jørn Wulff, 2019, In: Medicine and Science in Sports and Exercise. 51, 7, p. 1429-1437 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Aerobic and resistance exercise training reverses age-dependent decline in NAD(+) salvage capacity in human skeletal muscle

de Guia, R. M., Agerholm, M., Nielsen, Thomas Svava, Consitt, L. A., Sogaard, D., Helge, Jørn Wulff, Larsen, Steen, Brandauer, J., Houmard, J. A. & Treebak, Jonas Thue, 2019, In: Physiological Reports. 7, 12, 15 p., e14139.

Research output: Contribution to journal › Journal article › Research › peer-review

Aging in high functioning elderly persons: study design and analyses of behavioral and psychological factors

Finkenzeller, T., Poetzelsberger, B., Koesters, A., Wuerth, S., Amesberger, G., Dela, Flemming & Mueller, E., 2019, In: Scandinavian Journal of Medicine & Science in Sports. 29, p. 7-16

Research output: Contribution to journal › Journal article › Research › peer-review

Are skin senescence and immunosenescence linked within individuals?

Waaijer, M. E. C., Goldeck, D., Gunn, D. A., van Heemst, D., Westendorp, Rudi GJ, Pawelec, G. & Maier, A. B., 2019, In: Aging Cell. 18, 4, 5 p., e12956.

Research output: Contribution to journal › Journal article › Research › peer-review

Assessment of maximal fat oxidation during exercise: A systematic review

Amaro-Gahete, F. J., Sanchez-Delgado, G., Jurado-Fasoli, L., De-la-O, A., Castillo, M. J., Helge, Jørn Wulff & Ruiz, J. R., 2019, In: Scandinavian Journal of Medicine & Science in Sports. 29, 7, p. 910-921

Research output: Contribution to journal › Review › Research › peer-review

Association Between Levothyroxine Treatment and Thyroid-Related Symptoms Among Adults Aged 80 Years and Older With Subclinical Hypothyroidism

Mooijaart, S. P., Du Puy, R. S., Stott, D. J., Kearney, P. M., Rodondi, N., Westendorp, R. G. J., den Elzen, W. P. J., Postmus, I., Poortvliet, R. K. E., van Heemst, D., van Munster, B. C., Peeters, R. P., Ford, I., Kean, S., Messow, C-M., Blum, M. R., Collet, T-H., Watt, T., Dekkers, O. M., Jukema, J. W. & 3 others, Smit, J. W. A., Langhorne, P. & Gussekloo, J., 2019, In: J A M A: The Journal of the American Medical Association. 322, 20, p. 1977-1986 10 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Cardiovascular, muscular, and skeletal adaptations to recreational team handball training: a randomized controlled trial with young adult untrained men

Hornstrup, T., Løwenstein, F. T., Larsen, M. A., Helge, Eva Wulff, Póvoas, S., Helge, Jørn Wulff, Nielsen, Jens Jung, Fristrup, B., Andersen, J. L., Gliemann, Lasse, Nybo, Lars & Krustrup, P., 2019, In: European Journal of Applied Physiology. 119, 2, p. 561-573 13 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Clusters of Glycemic Response to Oral Glucose Tolerance Tests Explain Multivariate Metabolic and Anthropometric Outcomes of Bariatric Surgery in Obese Patients

Szczerbinski, L., Taylor, M. A., Citko, A., Gorska, M., Larsen, Steen, Hady, H. R. & Kretowski, A., 2019, In: Journal of Clinical Medicine. 8, 8, 16 p., 1091.

Research output: Contribution to journal › Journal article › Research › peer-review

Cockayne syndrome group B deficiency reduces H3K9me3 chromatin remodeler SETDB1 and exacerbates cellular aging

Lee, J., Demarest, T. G., Babbar, M., Kim, E. W., Okur, M. N., De, S., Croteau, D. L. & Bohr, Vilhelm, 2019, In: Nucleic Acids Research. 47, 16, p. 8548-8562

Research output: Contribution to journal › Journal article › Research › peer-review

Coenzyme Q10 does not improve peripheral insulin sensitivity in statin-treated men and women: the LIFESTAT study

Kuhlman, A. B., Morville, T., Dohlmann, T. L., Hansen, M., Kelly, B., Helge, Jørn Wulff & Dela, Flemming, 2019, In: Applied Physiology, Nutrition and Metabolism. 44, p. 485–492

Research output: Contribution to journal › Journal article › Research › peer-review

Copenhagen Consensus statement 2019: Physical activity and ageing

Bangsbo, J., Blackwell, J., Boraxbekk, C-J., Caserotti, P., Dela, F., Evans, A. B., Jespersen, A. P., Gliemann, L., Kramer, A. F., Lundbye-Jensen, J., Mortensen, E. L., Lassen, A. J., Gow, A. J., Harridge, S. D. R., Hellsten, Y., Kjær, M., Kujala, U. M., Rhodes, R. E., Pike, E. C. J., Skinner, T. & 6 others, Skovgaard, T., Troelsen, J., Tulle, E., Tully, M. A., van Uffelen, J. G. Z. & Viña, J., 2019, In: British Journal of Sports Medicine. 53, 14, p. 856-858 3 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Determination and validation of peak fat oxidation in endurance-trained men using an upper body graded exercise test

Hansen, Mikkel Thunestvedt, Rømer, Tue, Frandsen, J., Larsen, Steen, Dela, Flemming & Helge, Jørn Wulff, 2019, In: Scandinavian Journal of Medicine & Science in Sports. 29, 11, p. 1677-1690

Research output: Contribution to journal › Journal article › Research › peer-review

Diminished OPA1 expression and impaired mitochondrial morphology and homeostasis in Aprataxin-deficient cells

Zheng, Jin, Croteau, D. L., Bohr, Vilhelm & Akbari, M., 2019, In: Nucleic Acids Research. 47, 8, p. 4086–4110

Research output: Contribution to journal › Journal article › Research › peer-review

Diurnal Variation of Maximal Fat-Oxidation Rate in Trained Male Athletes

Amaro-Gahete, F. J., Jurado-Fasoli, L., Trivino, A. R., Sanchez-Delgado, G., De-la-O, A., Helge, Jørn Wulff & Ruiz, J. R., 2019, In: International Journal of Sports Physiology and Performance. 14, 8, p. 1140-1146

Research output: Contribution to journal › Journal article › Research › peer-review

Do psychosocial factors modify the negative association between disability and life satisfaction in old age?

Puvill, T., Kusumastuti, S., Lund, Rikke, Mortensen, Erik Lykke, Slaets, J., Lindenberg, J. & Westendorp, Rudi GJ, 2019, In: P L o S One. 14, 10, 15 p., e0224421.

Research output: Contribution to journal › Journal article › Research › peer-review

Effect of the mineralocorticoid receptor antagonist eplerenone on liver fat and metabolism in patients with type 2 diabetes: A randomized, double-blind, placebo-controlled trial (MIRAD trial)

Johansen, M. L., Schou, Morten, Rossignol, P., Holm, M. R., Rasmussen, J., Brandt, N., Frandsen, M., Chabanova, E., Dela, Flemming, Faber, Jens & Kistorp, Caroline Michaela Nervil, 2019, In: Diabetes, Obesity and Metabolism. 21, 10, p. 2305-2314 10 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Effects of one-legged high-intensity interval training on insulin-mediated skeletal muscle glucose homeostasis in patients with type 2 diabetes

Dela, Flemming, Ingersen, Arthur, Andersen, N. B., Nielsen, M. B., Petersen, H. H. H., Hansen, C. N., Larsen, Steen, Wojtaszewski, Jørgen F P & Helge, Jørn Wulff, 2019, In: Acta Physiologica (Print). 226, 2, 18 p., e13245.

Research output: Contribution to journal › Journal article › Research › peer-review

Glucose metabolism dysregulation affects the transcriptome of skeletal muscle and responds to three-month exercise intervention in humans

Szczerbinski, L., Niemira, M., Szczerbinski, K., Puchta, U., Taylor, M., Citko, A., Siewiec, E., Zapolska, J., Larsen, Steen, Gorska, M. & Kretowski, A., 2019, In: Diabetologia. 62, Supl. 1/SI, p. S66-S66 127.

Research output: Contribution to journal › Conference abstract in journal › Research

Impact of data analysis methods for maximal fat oxidation estimation during exercise in sedentary adults Data analysis maximal fat oxidation

Amaro-Gahete, F. J., Sanchez-Delgado, G., Alcantara, J. M. A., Martinez-Tellez, B., Acosta, F. M., Helge, Jørn Wulff & Ruiz, J. R., 2019, In: European Journal of Sport Science. 19, 9, p. 1230-1239,

Research output: Contribution to journal › Journal article › Research › peer-review

Impaired mitochondrial oxidative phosphorylation capacity in epicardial adipose tissue is associated with decreased concentration of adiponectin and severity of coronary atherosclerosis

Nakajima, T., Yokota, T., Shingu, Y., Yamada, A., Iba, Y., Ujihira, K., Wakasa, S., Ooka, T., Takada, S., Shirakawa, R., Katayama, T., Furihata, T., Fukushima, A., Matsuoka, R., Nishihara, H., Dela, Flemming, Nakanishi, K., Matsui, Y. & Kinugawa, S., 2019, In: Scientific Reports. 9, 1, 3535.

Research output: Contribution to journal › Journal article › Research › peer-review

Increased oxidation of RNA despite reduced mitochondrial respiration after chronic electroconvulsive stimulation of rat brain tissue

Nielsen, B., Cejvanovic, V., Wortwein, G., Hansen, A. R., Marstal, K. K., Weimann, A., Bjerring, P. N., Dela, Flemming, Poulsen, Henrik Enghusen & Jørgensen, Martin Balslev, 2019, In: Neuroscience Letters. 690, p. 1-5

Research output: Contribution to journal › Journal article › Research › peer-review

Inflammatory biomarkers in patients in Simvastatin treatment: No effect of co-enzyme Q10 supplementation

Hansen, M., Kuhlman, A. C. B., Sahl, Ronni Eg, Kelly, B., Morville, T., Dohlmann, T. L., Chrøis, K. M., Larsen, S., Helge, Jørn Wulff & Dela, Flemming, 2019, In: Cytokine. 113, p. 393-399 7 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Influence of exercise amount and intensity on long-term weight loss maintenance and skeletal muscle mitochondrial ROS production in humans

Larsen, Steen, Dandanell, S., Kristensen, K. B., Jorgensen, S. D., Dela, Flemming & Helge, Jørn Wulff, 2019, In: Applied Physiology, Nutrition and Metabolism. 44, 9, p. 958-964

Research output: Contribution to journal › Journal article › Research › peer-review

Lamin A/C promotes DNA base excision repair

Maynard, S., Keijzers, G., Akbari, M., Ben Ezra, Michael, Hall, A., Morevati, M., Scheibye-Knudsen, Morten, Gonzalo, S., Bartek, J. & Bohr, Vilhelm, 2019, In: Nucleic Acids Research. 47, 22, p. 11709–11728

Research output: Contribution to journal › Journal article › Research › peer-review

Low N-terminal pro-brain natriuretic peptide levels are associated with non-alcoholic fatty liver disease in patients with type 2 diabetes

Johansen, M. L., Schou, Morten, Rasmussen, J., Rossignol, P., Holm, M. R., Chabanova, E., Dela, Flemming, Faber, Jens & Kistorp, Caroline Michaela Nervil, 2019, In: Diabetes & Metabolism. 45, 5, p. 429-435

Research output: Contribution to journal › Journal article › Research › peer-review

Mitochondria in the signaling pathways that control longevity and health span

Akbari, M., Kirkwood, T. B. L. & Bohr, Vilhelm, 2019, In: Ageing Research Reviews. 54, 100940.

Research output: Contribution to journal › Review › Research › peer-review

Mitochondrial function in liver cells is resistant to perturbations in NAD⁺ salvage capacity

Dall, M., Trammell, Sam, Asping, M., Hassing, Anna Skab, Agerholm, M., Vienberg, S. G., Gillum, M. P., Larsen, Steen & Treebak, Jonas Thue, 2019, In: The Journal of Biological Chemistry. 294, 36, p. 13304-13326 23 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Mitochondrial reactive oxygen species generation in blood cells is associated with disease severity and exercise intolerance in heart failure patients

Shirakawa, R., Yokota, T., Nakajima, T., Takada, S., Yamane, M., Furihata, T., Maekawa, S., Nambu, H., Katayama, T., Fukushima, A., Saito, A., Ishimori, N., Dela, Flemming, Kinugawa, S. & Anzai, T., 2019, In: Scientific Reports. 9, 8 p., 14709.

Research output: Contribution to journal › Journal article › Research › peer-review

Mitophagy inhibits amyloid-β and tau pathology and reverses cognitive deficits in models of Alzheimer's disease

Fang, E. F., Hou, Y., Palikaras, K., Adriaanse, B. A., Kerr, J. S., Yang, B., Lautrup, S., Hasan-Olive, M. M., Caponio, D., Dan, X., Rocktäschel, P., Croteau, D. L., Akbari, M., Greig, N. H., Fladby, T., Nilsen, H., Cader, M. Z., Mattson, M. P., Tavernarakis, N. & Bohr, Vilhelm, 2019, In: Nature Neuroscience. 22, p. 401-412

Research output: Contribution to journal › Journal article › Research › peer-review

Muscle-Saturated Bioactive Lipids Are Increased with Aging and Influenced by High-Intensity Interval Training

Søgaard, D., Baranowski, M., Larsen, Steen, Taulo Lund, M., Munk Scheuer, C., Vestergaard Abildskov, C., Greve Dideriksen, S., Dela, Flemming & Helge, Jørn Wulff, 2019, In: International Journal of Molecular Sciences . 20, 5, 1240.

Research output: Contribution to journal › Journal article › Research › peer-review

NAD+ augmentation restores mitophagy and limits accelerated aging in Werner syndrome

Fang, E. F., Hou, Y., Lautrup, S., Jensen, M. B., Yang, B., SenGupta, T., Caponio, D., Khezri, R., Demarest, T. G., Aman, Y., Figueroa, D., Morevati, M., Lee, H-J., Kato, H., Kassahun, H., Lee, J-H., Filippelli, D., Okur, M. N., Mangerich, A., Croteau, D. L. & 9 others, Maezawa, Y., Lyssiotis, C. A., Tao, J., Yokote, K., Rusten, T. E., Mattson, M. P., Jasper, H., Nilsen, H. & Bohr, Vilhelm, 2019, In: Nature Communications. 10, 1, 18 p., 5284.

Research output: Contribution to journal › Journal article › Research › peer-review

NEIL1 stimulates neurogenesis and suppresses neuroinflammation after stress

Yang, B., Figueroa, D. M., Hou, Y., Babbar, M., Baringer, S. L., Croteau, D. L. & Bohr, Vilhelm, 2019, In: Free Radical Biology and Medicine. 141, p. 47-58 12 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Night shift work, long working hours and dementia: a longitudinal study of the Danish Work Environment Cohort

Nabe-Nielsen, Kirsten, Hansen, Åse Marie, Ishtiak-Ahmed, K., Brodsgaard Grynderup, M., Gyntelberg, F., Islamoska, S., Mortensen, Erik Lykke, Phung, T. K. T., Rod, Naja Hulvej, Waldemar, Gunhild, Westendorp, Rudi GJ & Garde, A. H., 2019, In: BMJ Open.

Research output: Contribution to journal › Journal article › Research › peer-review

Optimizing Maximal Fat Oxidation Assessment by a Treadmill-Based Graded Exercise Protocol: When Should the Test End?

Amaro-Gahete, F. J., Sanchez-Delgado, G., Helge, Jørn Wulff & Ruiz, J. R., 2019, In: Frontiers in Physiology. 10, 5 p., 909.

Research output: Contribution to journal › Journal article › Research › peer-review

Plasma free fatty acid concentration is closely tied to whole-body peak fat oxidation rate during repeated exercise

Frandsen, J., Vest, S. D., Ritz, C., Larsen, Steen, Dela, Flemming & Helge, Jørn Wulff, 2019, In: Journal of Applied Physiology. 126, 6, p. 1563-1571 9 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Pre-ischemic succinate dehydrogenase inhibition is protective against ischemia-reperfusion injury in rat and human myocardium with and without diabetes mellitus: [Meeting Abstract]

Jespersen, N. R., Hjortbak, M. V., Lassen, T. R., Stoettrup, N. B., Johnsen, J., Tonnesen, P. T., Larsen, Steen, Kimose, H. H. & Boetker, H. E., 2019, In: European Heart Journal. 40, S.1, p. 2101-2101 P3487 .

Research output: Contribution to journal › Conference abstract in journal › Research

Subclinical thyroid dysfunction and depressive symptoms: protocol for a systematic review and individual participant data meta-analysis of prospective cohort studies

Wildisen, L., Moutzouri, E., Beglinger, S., Syrogiannouli, L., Cappola, A. R., Åsvold, B. O., Bakker, S. J. L., Ceresini, G., Dullaart, R., Ferrucci, L., Grabe, H., Jukema, J. W., Nauck, M., Trompet, S., Voelzke, H., Westendorp, R. G. J., Gussekloo, J., Peeters, R. P., Kloeppel, S., Aujesky, D. & 4 others, Bauer, D. C., Rodondi, N., Del Giovane, C. & Feller, M., 2019, In: BMJ Open. 9, 7, 4 p., 029716.

Research output: Contribution to journal › Review › Research › peer-review

The influence of age and cardiorespiratory fitness on bioactive lipids in muscle

Søgaard, D., Baranowski, M., Dela, Flemming & Helge, Jørn Wulff, 2019, In: The journals of gerontology. Series A, Biological sciences and medical sciences. 74, 6, p. 778-786

Research output: Contribution to journal › Journal article › Research › peer-review

The rise of statins in Denmark: Making the case for a localized approach to the routinization of pharmaceutical prevention of cardiovascular disease

Lau, Sofie Rosenlund, Andersen, John Sahl, Dela, Flemming & Oxlund, Bjarke, 2019, In: BioSocieties. 14, 2, p. 228-250 23 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Trajectories of cardio-metabolic health in successful aging

Dela, Flemming, Finkenzeller, T., Ingersen, Arthur, Poetzelsberger, B. & Mueller, E., 2019, In: Scandinavian Journal of Medicine & Science in Sports. 29, p. 44-51

Research output: Contribution to journal › Journal article › Research › peer-review

Obesity leads to impairments in the morphology and organization of human skeletal muscle lipid droplets and mitochondrial networks, which are resolved with gastric bypass surgery-induced improvements in insulin sensitivity

Kristensen, M. D., Petersen, S. M., Møller, Kristina, Lund, Morten Asp Vonsild, Hansen, M., Hansen, C. N., Courraud, J., Helge, Jørn Wulff, Dela, Flemming & Prats Gavalda, Clara, Dec 2018, In: Acta Physiologica (Print). 224, 4, 15 p., e13100 .

Research output: Contribution to journal › Journal article › Research › peer-review

The combination of cardiorespiratory fitness and muscle strength, and mortality risk

Kim, Y., White, T., Wijndaele, K., Westgate, K., Sharp, S. J., Helge, Jørn Wulff, Wareham, N. J. & Brage, S., 1 Oct 2018, In: European Journal of Epidemiology. 33, 10, p. 953-964 12 p.

Research output: Contribution to journal › Journal article › Research › peer-review

High-intensity interval training changes mitochondrial respiratory capacity differently in adipose tissue and skeletal muscle

Dohlmann, T. L., Hindsø, M., Dela, Flemming, Helge, Jørn Wulff & Larsen, S., 1 Sep 2018, In: Physiological Reports. 6, 18, p. 1-11 e13857.

Research output: Contribution to journal › Journal article › Research › peer-review

Variation in mitochondrial respiratory capacity and myosin heavy chain composition in repeated muscle biopsies

Sahl, Ronni Eg, Morville, T., Kraunsøe, R., Dela, Flemming, Helge, Jørn Wulff & Larsen, Steen, 1 Sep 2018, In: Analytical Biochemistry. 556, p. 119-124 6 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Mitochondrial respiratory capacity remains stable despite a comprehensive and sustained increase in insulin sensitivity in obese patients undergoing gastric bypass surgery

Lund, M. T., Larsen, Steen, Hansen, M., Courraud, J., Floyd, A. K., Støckel, M., Helge, Jørn Wulff & Dela, Flemming, 1 May 2018, In: Acta Physiologica. 223, 1, p. 1-9 e13032.

Research output: Contribution to journal › Journal article › Research › peer-review

High-intensity interval training improves insulin sensitivity in older individuals

Søgaard, D., Lund, M. T., Scheuer, C. M., Dehlbaek, M. S., Dideriksen, S. G., Abildskov, C. V., Christensen, K. K., Dohlmann, T. L., Larsen, Steen, Vigelsø, A. H., Dela, Flemming & Helge, Jørn Wulff, Apr 2018, In: Acta Physiologica (Print). 222, 4, e13009.

Research output: Contribution to journal › Journal article › Research › peer-review

Effects of 6-month aerobic interval training on skeletal muscle metabolism in middle-aged metabolic syndrome patients

Guadalupe-Grau, A., Fernández-Elías, V. E., Ortega, J. F., Dela, Flemming, Helge, Jørn Wulff & Mora-Rodriguez, R., Feb 2018, In: Scandinavian Journal of Medicine & Science in Sports. 28, 2, p. 585-595 11 p.

Research output: Contribution to journal › Journal article › Research › peer-review

GIP(3-30)NH₂ is an efficacious GIP receptor antagonist in humans: a randomised, double-blinded, placebo-controlled, crossover study

Gasbjerg, Lærke Smidt, Christensen, Mikkel Bring, Hartmann, Bolette, Lanng, A. R., wbf943, wbf943, Gabe, M. B. N., Dela, Flemming, Vilsbøll, Tina, Holst, Jens Juul, Rosenkilde, Mette & Knop, Filip Krag, Feb 2018, In: Diabetologia. 61, 2, p. 413-423

Research output: Contribution to journal › Journal article › Research › peer-review

Associations between vitamin D status and atherosclerosis among Inuit in Greenland

Gjødesen, C. U., Jørgensen, M. E., Bjerregaard, P., Dahl-Petersen, I. K., Larsen, C. V. L., Noël, M., Melbye, M., Cohen, A. S., Lundqvist, M., Hougaard, D. M., Helge, Jørn Wulff & Nielsen, N. O., Jan 2018, In: Atherosclerosis. 268, p. 145-151 7 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Social Relations at Work and Incident Dementia: 29-Years' Follow-Up of the Copenhagen Male Study

Ishtiak-Ahmed, K., Hansen, Åse Marie, Garde, A. H., Mortensen, Erik Lykke, Gyntelberg, F., Phung, T. K. T., Lund, Rikke, Rod, Naja Hulvej, Prescott, Eva, Waldemar, Gunhild, Westendorp, Rudi GJ & Nabe-Nielsen, Kirsten, Jan 2018, In: Journal of Occupational and Environmental Medicine. 60, 1, p. 12–18 7 p.

Research output: Contribution to journal › Journal article › Research › peer-review

2706 km cycling in 2 weeks: effects on cardiac function in 6 elderly male athletes

Morville, T., Rosenkilde, M., Mattsson, N., Dela, Flemming, Helge, Jørn Wulff & Rasmusen, Hanne K., 2018, In: Physician and Sportsmedicine. 46, 3, p. 263-268 6 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Bone mineral density in lifelong trained male football players compared with young and elderly untrained men

Hagman, M., Helge, Eva Wulff, Hornstrup, T., Fristrup, B., Nielsen, Jens Jung, Jørgensen, N. R., Andersen, J. L., Helge, Jørn Wulff & Krustrup, P., 2018, In: Journal of Sport and Health Science. 7, 2, p. 159-168 10 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Divergent effects of resistance and endurance exercise on plasma bile acids, FGF19, and FGF21 in humans

Morville, T., Sahl, Ronni Eg, Trammell, Sam, Svenningsen, J. S., Gillum, M. P., Helge, Jørn Wulff & Clemmensen, Christoffer, 2018, In: JCI Insight. 3, 15, p. 1-13 e122737.

Research output: Contribution to journal › Journal article › Research › peer-review

Exercise training increases skeletal muscle mitochondrial volume density by enlargement of existing mitochondria and not de novo biogenesis

Lundby, A. M., Jacobs, R. A., Gehrig, S., de Leur, J., Hauser, M., Bonne, T. C., Flück, D., Dandanell, S., Kirk, N., Kaech, A., Ziegler, U., Larsen, Steen & Lundby, C., 2018, In: Acta Physiologica (Print). 222, 1, 14 p., e12905.

Research output: Contribution to journal › Journal article › Research › peer-review

Fitness and health benefits of team handball training for young untrained women - A cross-disciplinary RCT on physiological adaptations and motivational aspects

Hornstrup, T., Wikman, J. M., Fristrup, B., Póvoas, S., Helge, Eva Wulff, Nielsen, S. H., Helge, Jørn Wulff, Andersen, J. L., Nybo, Lars & Krustrup, P., 2018, In: Journal of Sport and Health Science. 7, 2, p. 139-148 10 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Football training over 5 years is associated with preserved femoral bone mineral density in men with prostate cancer

Uth, J., Fristrup, B., Haahr, R. D., Brasso, K., Helge, Jørn Wulff, Rørth, M. R., Midtgaard, Julie, Helge, Eva Wulff & Krustrup, P., 2018, In: Scandinavian Journal of Medicine & Science in Sports. 28, Suppl. 1, p. 61-73 13 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Four days of bed rest increases intrinsic mitochondrial respiratory capacity in young healthy males

Larsen, Steen, Lundby, A. M., Dandanell, S., Oberholzer, L., Keiser, S., Andersen, A. B., Haider, T. & Lundby, C., 2018, In: Physiological Reports. 6, 18, 9 p., e13793.

Research output: Contribution to journal › Journal article › Research › peer-review

Hypertension treatment for older people-navigating between Scylla and Charybdis

Conroy, S. P., Westendorp, Rudi GJ & Witham, M. D., 2018, In: Age and Ageing. 47, 4, p. 505-508 4 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Impact of Thyroid Hormone Therapy on Atherosclerosis in the Elderly With Subclinical Hypothyroidism: A Randomized Trial

Blum, M. R., Gencer, B., Adam, L., Feller, M., Collet, T., da Costa, B. R., Moutzouri, E., Dopheide, J., Depairon, M., Sykiotis, G. P., Kearney, P., Gussekloo, J., Westendorp, Rudi GJ, Stott, D. J., Bauer, D. C. & Rodondi, N., 2018, In: The Journal of clinical endocrinology and metabolism. 103, 8, p. 2988-2997 10 p.

Research output: Contribution to journal › Journal article › Research › peer-review

Impact of Thyroid Hormone Therapy on Bone Health in Older Adults with Subclinical Hypothyroidism: a Randomized Clinical Trial

Rodriguez, E. G., Lowe, A. L., Del Giovane, C., Feller, M., Kearney, P., Gussekloo, J., Mooijaart, S. P., Westendorp, Rudi GJ, Stott, D. J., Aeberli, D., Bauer, D., Hans, D. & Rodondi, N., 2018, In: Journal of Bone and Mineral Research. 33, p. 317-318 2 p., 1223.

Research output: Contribution to journal › Conference abstract in journal › Research › peer-review