Individualized Health

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  1. 2018
  2. Published

    Effects of 6-month aerobic interval training on skeletal muscle metabolism in middle-aged metabolic syndrome patients

    Guadalupe-Grau, A., Fernández-Elías, V. E., Ortega, J. F., Dela, Flemming, Helge, Jørn Wulff & Mora-Rodriguez, R., Feb 2018, In: Scandinavian Journal of Medicine & Science in Sports. 28, 2, p. 585-595 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    GIP(3-30)NH2 is an efficacious GIP receptor antagonist in humans: a randomised, double-blinded, placebo-controlled, crossover study

    Gasbjerg, Lærke Smidt, Christensen, Mikkel Bring, Hartmann, Bolette, Lanng, A. R., wbf943, wbf943, Gabe, M. B. N., Dela, Flemming, Vilsbøll, Tina, Holst, Jens Juul, Rosenkilde, Mette & Knop, Filip Krag, Feb 2018, In: Diabetologia. 61, 2, p. 413-423

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Associations between vitamin D status and atherosclerosis among Inuit in Greenland

    Gjødesen, C. U., Jørgensen, M. E., Bjerregaard, P., Dahl-Petersen, I. K., Larsen, C. V. L., Noël, M., Melbye, M., Cohen, A. S., Lundqvist, M., Hougaard, D. M., Helge, Jørn Wulff & Nielsen, N. O., Jan 2018, In: Atherosclerosis. 268, p. 145-151 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Social Relations at Work and Incident Dementia: 29-Years' Follow-Up of the Copenhagen Male Study

    Ishtiak-Ahmed, K., Hansen, Åse Marie, Garde, A. H., Mortensen, Erik Lykke, Gyntelberg, F., Phung, T. K. T., Lund, Rikke, Rod, Naja Hulvej, Prescott, Eva, Waldemar, Gunhild, Westendorp, Rudi GJ & Nabe-Nielsen, Kirsten, Jan 2018, In: Journal of Occupational and Environmental Medicine. 60, 1, p. 12–18 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    2706 km cycling in 2 weeks: effects on cardiac function in 6 elderly male athletes

    Morville, T., Rosenkilde, M., Mattsson, N., Dela, Flemming, Helge, Jørn Wulff & Rasmusen, Hanne K., 2018, In: Physician and Sportsmedicine. 46, 3, p. 263-268 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Bone mineral density in lifelong trained male football players compared with young and elderly untrained men

    Hagman, M., Helge, Eva Wulff, Hornstrup, T., Fristrup, B., Nielsen, Jens Jung, Jørgensen, N. R., Andersen, J. L., Helge, Jørn Wulff & Krustrup, P., 2018, In: Journal of Sport and Health Science. 7, 2, p. 159-168 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Divergent effects of resistance and endurance exercise on plasma bile acids, FGF19, and FGF21 in humans

    Morville, T., Sahl, Ronni Eg, Trammell, Sam, Svenningsen, J. S., Gillum, M. P., Helge, Jørn Wulff & Clemmensen, Christoffer, 2018, In: JCI Insight. 3, 15, p. 1-13 e122737.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Exercise training increases skeletal muscle mitochondrial volume density by enlargement of existing mitochondria and not de novo biogenesis

    Lundby, A. M., Jacobs, R. A., Gehrig, S., de Leur, J., Hauser, M., Bonne, T. C., Flück, D., Dandanell, S., Kirk, N., Kaech, A., Ziegler, U., Larsen, Steen & Lundby, C., 2018, In: Acta Physiologica (Print). 222, 1, 14 p., e12905.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Fitness and health benefits of team handball training for young untrained women - A cross-disciplinary RCT on physiological adaptations and motivational aspects

    Hornstrup, T., Wikman, J. M., Fristrup, B., Póvoas, S., Helge, Eva Wulff, Nielsen, S. H., Helge, Jørn Wulff, Andersen, J. L., Nybo, Lars & Krustrup, P., 2018, In: Journal of Sport and Health Science. 7, 2, p. 139-148 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Football training over 5 years is associated with preserved femoral bone mineral density in men with prostate cancer

    Uth, J., Fristrup, B., Haahr, R. D., Brasso, K., Helge, Jørn Wulff, Rørth, M. R., Midtgaard, Julie, Helge, Eva Wulff & Krustrup, P., 2018, In: Scandinavian Journal of Medicine & Science in Sports. 28, Suppl. 1, p. 61-73 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Four days of bed rest increases intrinsic mitochondrial respiratory capacity in young healthy males

    Larsen, Steen, Lundby, A. M., Dandanell, S., Oberholzer, L., Keiser, S., Andersen, A. B., Haider, T. & Lundby, C., 2018, In: Physiological Reports. 6, 18, 9 p., e13793.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Hypertension treatment for older people-navigating between Scylla and Charybdis

    Conroy, S. P., Westendorp, Rudi GJ & Witham, M. D., 2018, In: Age and Ageing. 47, 4, p. 505-508 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Impact of Thyroid Hormone Therapy on Atherosclerosis in the Elderly With Subclinical Hypothyroidism: A Randomized Trial

    Blum, M. R., Gencer, B., Adam, L., Feller, M., Collet, T., da Costa, B. R., Moutzouri, E., Dopheide, J., Depairon, M., Sykiotis, G. P., Kearney, P., Gussekloo, J., Westendorp, Rudi GJ, Stott, D. J., Bauer, D. C. & Rodondi, N., 2018, In: The Journal of clinical endocrinology and metabolism. 103, 8, p. 2988-2997 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Impact of Thyroid Hormone Therapy on Bone Health in Older Adults with Subclinical Hypothyroidism: a Randomized Clinical Trial

    Rodriguez, E. G., Lowe, A. L., Del Giovane, C., Feller, M., Kearney, P., Gussekloo, J., Mooijaart, S. P., Westendorp, Rudi GJ, Stott, D. J., Aeberli, D., Bauer, D., Hans, D. & Rodondi, N., 2018, In: Journal of Bone and Mineral Research. 33, p. 317-318 2 p., 1223.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  16. Published

    NAD+ supplementation normalizes key Alzheimer’s features and DNA damage responses in a new AD mouse model with introduced DNA repair deficiency

    Hou, Y., Lautrup, S., Cordonnier, S., Wang, Y., Croteau, D. L., Zavala, E., Zhang, Y., Moritoh, K., O’Connell, J. F., Baptiste, B. A., Stevnsner, T. V., Mattson, M. P. & Bohr, Vilhelm, 2018, In: Proceedings of the National Academy of Sciences of the United States of America. 115, 8, p. E1876-E1885

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Peak Fat Oxidation is Not Independently Related to Ironman Performance in Women

    Vest, S. D., Frandsen, J., Larsen, S., Dela, Flemming & Helge, Jørn Wulff, 2018, In: International Journal of Sports Medicine. 39, 12, p. 916-923

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Perturbations of NAD+ salvage systems impact mitochondrial function and energy homeostasis in mouse myoblasts and intact skeletal muscle

    Andersen, M. A., Dall, M., Jensen, Benjamin Anderschou Holbech, Prats Gavalda, Clara, Madsen, S., Basse, A. L., Graae, A., Risis, S., Goldenbaum, J., Quistorff, B., Larsen, Steen, Vienberg, S. G. & Treebak, Jonas Thue, 2018, In: American Journal of Physiology: Endocrinology and Metabolism. 314, 4, p. E377-E395 19 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Sarcopenia, Aging and Prospective Interventional Strategies

    Waltz, T. B., Fivenson, E. M., Morevati, M., Li, C., Becker, K. G., Bohr, Vilhelm & Fang, E. F., 2018, In: Current Medicinal Chemistry. 25, 40, p. 5588-5596 9 p.

    Research output: Contribution to journal › Review › Research › peer-review

  20. Published

    Simvastatin-Induced Insulin Resistance May Be Linked to Decreased Lipid Uptake and Lipid Synthesis in Human Skeletal Muscle: the LIFESTAT Study

    Larsen, S., Vigelsø, A., Dandanell, S., Prats Gavalda, Clara, Dela, Flemming & Helge, Jørn Wulff, 2018, In: Journal of Diabetes Research. 2018, 7 p., 9257874 .

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    The added value of health indicators to mortality predictions in old age: A systematic review

    Kusumastuti, S., Rozing, Maarten Pieter, Lund, Rikke, Mortensen, Erik Lykke & Westendorp, Rudi GJ, 2018, In: European Journal of Internal Medicine. 57, p. 7-18 12 p.

    Research output: Contribution to journal › Review › Research › peer-review

  22. Published

    The dynamic life of the glycogen granule

    Prats Gavalda, Clara, Graham, T. E. & Shearer, J., 2018, In: Journal of Biological Chemistry. 293, 19, p. 7089-7098

    Research output: Contribution to journal › Review › Research › peer-review

  23. Published

    Thyroid Stimulating Hormone and Bone Mineral Density: Evidence From a Two-Sample Mendelian Randomization Study and a Candidate Gene Association Study

    van Vliet, N. A., Noordam, R., van Klinken, J. B., Westendorp, Rudi GJ, Bassett, J. D., Williams, G. R. & van Heemst, D., 2018, In: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. 33, 7, p. 1318-1325 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. 2017
  25. Published

    When subclinical hypothyroidism becomes clinically diagnosed

    Nixon, M. & Westendorp, Rudi GJ, Dec 2017, In: European Journal of Internal Medicine. 46, p. e34-e35 2 p.

    Research output: Contribution to journal › Comment/debate › Research › peer-review

  26. Published

    Macrophage Area Content and Phenotype in Hepatic and Adipose Tissue in Patients with Obesity Undergoing Roux-en-Y Gastric Bypass

    Kristensen, M. D., Lund, M. T., Hansen, M., Poulsen, Steen Seier, Ploug, Thorkil, Dela, Flemming, Helge, Jørn Wulff & Prats Gavalda, Clara, Nov 2017, In: Obesity. 25, 11, p. 1921-1931 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    Effects of intranasal insulin application on the hypothalamic BOLD response to glucose ingestion

    van Opstal, A. M., Akintola, A. A., Elst, M. V. D., Westendorp, Rudi GJ, Pijl, H., van Heemst, D. & van der Grond, J., 17 Oct 2017, In: Scientific Reports. 7, p. 1-7 7 p., 13327.

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    Exercise training protects against aging-induced mitochondrial fragmentation in mouse skeletal muscle in a PGC-1α dependent manner

    Halling, Jens Frey, Jørgensen, Stine Ringholm, Olesen, J., Prats Gavalda, Clara & Pilegaard, Henriette, 1 Oct 2017, In: Experimental Gerontology. 96, p. 1-6 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    Leydig cell dysfunction, systemic inflammation and metabolic syndrome in long-term testicular cancer survivors

    Bandak, M., Jørgensen, N., Juul, A., Lauritsen, J., Oturai, P. S., Mortensen, Jann, Hojman, P., Helge, Jørn Wulff & Daugaard, G., Oct 2017, In: European Journal of Cancer. 84, p. 9-17 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    Thyroid status and mortality in nonagenarians from long-lived families and the general population

    van Vliet, N. A., van der Spoel, E., Beekman, M., Slagboom, P. E., Blauw, G. J., Gussekloo, J., Westendorp, Rudi GJ & van Heemst, D., Oct 2017, In: Aging. 9, 10, p. 2223—2234 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Published

    Bedside manners: How to deal with delirium

    Westendorp, Rudi GJ, Sep 2017, In: Cleveland Clinic Journal of Medicine. 84, 9, p. 699-700 2 p.

    Research output: Contribution to journal › Editorial › Research › peer-review

  32. Published

    Insulin sensitivity in relation to fat distribution and plasma adipocytokines among abusers of anabolic androgenic steroids

    Rasmussen, J. J., Schou, Morten, Selmer, C., Johansen, M. L., Gustafsson, Finn, Frystyk, J., Dela, Flemming, Faber, Jens & Kistorp, Caroline Michaela Nervil, Sep 2017, In: Clinical Endocrinology. 87, 3, p. 249-256 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. Published

    Raman probing of lipids, proteins, and mitochondria in skeletal myocytes: a case study on obesity

    Brazhe, N. A., Nikelshparg, E. I., Prats Gavalda, Clara, Dela, Flemming & Sosnovtseva, Olga, Sep 2017, In: Journal of Raman Spectroscopy. 48, 9, p. 1158-1165 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Published

    The Gluco- and Liporegulatory and Vasodilatory Effects of Glucose-Dependent Insulinotropic Polypeptide (GIP) Are Abolished by an Antagonist of the Human GIP Receptor

    Asmar, M., Asmar, A., Simonsen, L., Gasbjerg, Lærke Smidt, wbf943, wbf943, Rosenkilde, Mette, Hartmann, Bolette, Dela, Flemming, Holst, Jens Juul & Bülow, J., Sep 2017, In: Diabetes. 66, 9, p. 2363-2371 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. Published

    Thyroid function tests in the reference range and fracture: Individual participant analysis of prospective cohorts

    Aubert, C. E., Floriani, C., Bauer, D. C., da Costa, B. R., Segna, D., Blum, M. R., Collet, T-H., Fink, H. A., Cappola, A. R., Syrogiannouli, L., Peeters, R. P., Åsvold, B. O., den Elzen, W. P. J., Luben, R. N., Bremner, A. P., Gogakos, A., Eastell, R., Kearney, P. M., Hoff, M., Le Blanc, E. & 14 others, Ceresini, G., Rivadeneira, F., Uitterlinden, A. G., Khaw, K., Langhammer, A., Stott, D. J., Westendorp, Rudi GJ, Ferrucci, L., Williams, G. R., Gussekloo, J., Walsh, J. P., Aujesky, D., Rodondi, N. & Thyroid Studies Collaboration, T. S. C., 1 Aug 2017, In: The Journal of clinical endocrinology and metabolism. 102, 8, p. 2719–2728 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    DNA polymerase beta participates in mitochondrial DNA repair

    Sykora, P., Kanno, S., Akbari, M., Kulikowicz, T., Baptiste, B. A., Leandro, G. S., Lu, H., Tian, J., May, A., Becker, K. A., Croteau, D. L., Wilson, D. M., Sobol, R. W., Yasui, A. & Bohr, Vilhelm, Aug 2017, In: Molecular and Cellular Biology. 37, 16, e00237-17.

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Published

    Effect of APOE ε4 allele on survival and fertility in an adverse environment

    van Exel, E., Koopman, J. J. E., Bodegom, D. V., Meij, J. J., Knijff, P. D., Ziem, J. B., Finch, C. E. & Westendorp, Rudi GJ, 6 Jul 2017, In: PLOS ONE. 12, 7, p. 1-13 13 p., e0179497.

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. Published

    A randomized double-blind study of testosterone replacement therapy or placebo in testicular cancer survivors with mild Leydig cell insufficiency (Einstein-intervention)

    Bandak, M., Jørgensen, N., Juul, Anders, Lauritsen, J., Kreiberg, M., Oturai, P. S., Helge, Jørn Wulff & Daugaard, G., 3 Jul 2017, In: B M C Cancer. 17, 8 p., 461.

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. Published

    Discrimination ability of comorbidity, frailty, and subjective health to predict mortality in community-dwelling older people: Population based prospective cohort study

    Kusumastuti, S., Gerds, Thomas Alexander, Lund, Rikke, Mortensen, Erik Lykke & Westendorp, Rudi GJ, Jul 2017, In: European Journal of Internal Medicine. 42, p. 29-38 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  40. Published

    Influence of maximal fat oxidation on long-term weight loss maintenance in humans

    Dandanell, S., Husted, Karina Louise Skov, Amdisen, S., Vigelso, A., Dela, Flemming, Larsen, Steen & Helge, Jørn Wulff, Jul 2017, In: Journal of Applied Physiology. 123, 1, p. 267-274 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. Published

    Reproductive hormones and metabolic syndrome in 24 testicular cancer survivors and their biological brothers

    Bandak, M., Jorgensen, N., Juul, Anders, Lauritsen, J., Kier, M. G. G., Mortensen, M. S., Oturai, P. S., Mortensen, Jann, Hojman, P., Helge, Jørn Wulff & Daugaard, G., Jul 2017, In: Andrology. 5, 4, p. 718-724 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. Published

    Is there evidence for a limit to human lifespan?

    Rozing, Maarten Pieter, Kirkwood, T. B. L. & Westendorp, Rudi GJ, 29 Jun 2017, In: Nature. 546, 7660, p. E11-E12 2 p.

    Research output: Contribution to journal › Comment/debate › Research › peer-review

  43. Published

    Thyroid Hormone Therapy for Older Adults with Subclinical Hypothyroidism

    Stott, D. J., Rodondi, N., Kearney, P. M., Ford, I., Westendorp, R. G. J., Mooijaart, S. P., Sattar, N., Aubert, C. E., Aujesky, D., Bauer, D. C., Baumgartner, C., Blum, M. R., Browne, J. P., Byrne, S. L., Collet, T-H., Dekkers, O. M., den Elzen, W. P. J., Du Puy, R. S., Ellis, G., Feller, M. & 27 others, Floriani, C., Hendry, K., Hurley, C., Jukema, J. W., Kean, S., Kelly, M., Krebs, D., Langhorne, P., McCarthy, G., McCarthy, V., McConnachie, A., McDade, M., Messow, M., O’Flynn, A., O’Riordan, D., Poortvliet, R. K. E., Quinn, T. J., Russell, A., Sinnott, C., Smit, J. W. A., Van Dorland, H. A., Walsh, K. A., Walsh, E. K., Watt, T., Wilson, R., Gussekloo, J. & the TRUST Study Group, T. T. S. G., 29 Jun 2017, In: New England Journal of Medicine. 376, 26, p. 2534-2544 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Published

    Repeated Excessive Exercise Attenuates the Anti-Inflammatory Effects of Exercise in Older Men

    Sahl, Ronni Eg, Andersen, P. R., Gronbaek, K., Morville, T. H., Rosenkilde, M., Rasmusen, H. K., Poulsen, Steen Seier, Prats Gavalda, Clara, Dela, Flemming & Helge, Jørn Wulff, 22 Jun 2017, In: Frontiers in Physiology. 8, 6 p., 407.

    Research output: Contribution to journal › Journal article › Research › peer-review

  45. Published

    The effects of 2 weeks of statin treatment on mitochondrial respiratory capacity in middle-aged males: the LIFESTAT study

    Asping, M., Stride, N., Sogaard, D., Dohlmann, T. L., Helge, Jørn Wulff, Dela, Flemming & Larsen, S., Jun 2017, In: European Journal of Clinical Pharmacology. 73, 6, p. 679-687

    Research output: Contribution to journal › Journal article › Research › peer-review

  46. Published

    A high carbohydrate diet remains the evidence based choice for elite athletes to optimise performance

    Helge, Jørn Wulff, 1 May 2017, In: Journal of Physiology. 595, 9, p. 2775-2775

    Research output: Contribution to journal › Comment/debate › Research › peer-review

  47. Published

    Is there plasticity in mitochondrial cristae density with endurance training?

    Larsen, Steen, Helge, Jørn Wulff & Dela, Flemming, 1 May 2017, In: Journal of Physiology. 595, 9, p. 2985-2985 1 p.

    Research output: Contribution to journal › Comment/debate › Research › peer-review

  48. Published

    How is Change in Physical Health Status Reflected by Reports of Nurses and Older People Themselves?

    Puvill, T., Lindenberg, J., Slaets, J. P. J., de Craen, A. J. M. & Westendorp, Rudi GJ, 1 Apr 2017, In: Journals of Gerontology. Series A: Biological Sciences & Medical Sciences. 72, 4, p. 579–585 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  49. Published

    Determination of the exercise intensity that elicits maximal fat oxidation in individuals with obesity

    Jørgensen, S. D., Præst, C. B., Søndergård, S. D., Skovborg, C., Dela, Flemming, Larsen, Steen & Helge, Jørn Wulff, Apr 2017, In: Applied Physiology, Nutrition and Metabolism. 42, 4, p. 405-412 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  50. Published

    Maintaining a clinical weight loss after intensive lifestyle intervention is the key to cardiometabolic health

    Jørgensen, S. D., Skovborg, C., Præst, C. B., Kristensen, K. B., Nielsen, M. G., Lionett, S., Jørgensen, S. D., Vigelsø Hansen, A., Dela, Flemming & Helge, Jørn Wulff, Apr 2017, In: Obesity Research & Clinical Practice. 11, 4, p. 489-498 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  51. Published

    Effect of intranasally administered insulin on cerebral blood flow and perfusion: a randomized experiment in young and older adults

    Akintola, A. A., van Opstal, A. M., Westendorp, Rudi GJ, Postmus, I., van der Grond, J. & van Heemst, D., 14 Mar 2017, In: Aging. 9, 3, p. 790-802 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  52. Published

    Being Active, Engaged, and Healthy: Older Persons' Plans and Wishes to Age Successfully

    Huijg, J. M., van Delden, A. (. E. Q., van der Ouderaa, F. J. G., Westendorp, Rudi GJ, Slaets, J. P. J. & Lindenberg, J., 1 Mar 2017, In: Journals of Gerontology. Series B: Psychological Sciences & Social Sciences. 72, 2, p. 228-236 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

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