- 2019
- Published
Statin Treatment Decreases Mitochondrial Respiration But Muscle Coenzyme Q10 Levels Are Unaltered: The LIFESTAT Study
Dohlmann, T. L., Morville, T., Kuhlman, A. B., Chrøis, K. M., Helge, Jørn Wulff, Dela, Flemming & Larsen, Steen, Jul 2019, In: Journal of Clinical Endocrinology and Metabolism. 104, 7, p. 2501–2508Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effects of Long-Term Physical Activity and Diet on Skin Glycation and Achilles Tendon Structure
Hjerrild, J. N., Wobbe, A., Stausholm, M. B., Larsen, A. E., Josefsen, C. O., Malmgaard-Clausen, N. M., Dela, Flemming, Kjær, Michael, Magnusson, Stig Peter, Hansen, M., Svensson, R. B. & Couppé, C., 22 Jun 2019, In: Nutrients. 11, 6Research output: Contribution to journal › Journal article › Research › peer-review
- Published
GIP-induced vasodilation in human adipose tissue involves capillary recruitment
Asmar, M., Asmar, A., Simonsen, L., Dela, Flemming, Holst, Jens Juul & Bulow, J., Jun 2019, In: Endocrine Connections. 8, 6, p. 806-813Research output: Contribution to journal › Journal article › Research › peer-review
- Published
ADAMTS9 regulates skeletal muscle insulin sensitivity through extracellular matrix alterations
Graae, A-S., Grarup, N., Ribel-Madsen, R., Lystbæk, S. H., Boesgaard, T., Staiger, H., Fritsche, A., Wellner, N., Sulek, K., Kjølby, M. F., Backe, M. B., Chubanava, S., Prats, C., Serup, A. K. L., Birk, J. B., Dubail, J., Gillberg, L., Vienberg, S. G., Nykjær, A., Kiens, B. & 10 others, , 2019, In: Diabetes. 68, 3, p. 502-514Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Aerobic Exercise Performance and Muscle Strength in Statin Users-The LIFESTAT Study
Morville, T., Dohlmann, T. L., Kuhlman, A. B., Sahl, Ronni Eg, Kriegbaum, Margit, Larsen, Steen, Dela, Flemming & Helge, Jørn Wulff, 2019, In: Medicine and Science in Sports and Exercise. 51, 7, p. 1429-1437 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Aerobic and resistance exercise training reverses age-dependent decline in NAD(+) salvage capacity in human skeletal muscle
de Guia, R. M., Agerholm, M., Nielsen, Thomas Svava, Consitt, L. A., Sogaard, D., Helge, Jørn Wulff, Larsen, Steen, Brandauer, J., Houmard, J. A. & Treebak, Jonas Thue, 2019, In: Physiological Reports. 7, 12, 15 p., e14139.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Aging in high functioning elderly persons: study design and analyses of behavioral and psychological factors
Finkenzeller, T., Poetzelsberger, B., Koesters, A., Wuerth, S., Amesberger, G., Dela, Flemming & Mueller, E., 2019, In: Scandinavian Journal of Medicine & Science in Sports. 29, p. 7-16Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Are skin senescence and immunosenescence linked within individuals?
Waaijer, M. E. C., Goldeck, D., Gunn, D. A., van Heemst, D., Westendorp, Rudi GJ, Pawelec, G. & Maier, A. B., 2019, In: Aging Cell. 18, 4, 5 p., e12956.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Assessment of maximal fat oxidation during exercise: A systematic review
Amaro-Gahete, F. J., Sanchez-Delgado, G., Jurado-Fasoli, L., De-la-O, A., Castillo, M. J., Helge, Jørn Wulff & Ruiz, J. R., 2019, In: Scandinavian Journal of Medicine & Science in Sports. 29, 7, p. 910-921Research output: Contribution to journal › Review › Research › peer-review
- Published
Association Between Levothyroxine Treatment and Thyroid-Related Symptoms Among Adults Aged 80 Years and Older With Subclinical Hypothyroidism
Mooijaart, S. P., Du Puy, R. S., Stott, D. J., Kearney, P. M., Rodondi, N., Westendorp, R. G. J., den Elzen, W. P. J., Postmus, I., Poortvliet, R. K. E., van Heemst, D., van Munster, B. C., Peeters, R. P., Ford, I., Kean, S., Messow, C-M., Blum, M. R., Collet, T-H., Watt, T., Dekkers, O. M., Jukema, J. W. & 3 others, , 2019, In: J A M A: The Journal of the American Medical Association. 322, 20, p. 1977-1986 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cardiovascular, muscular, and skeletal adaptations to recreational team handball training: a randomized controlled trial with young adult untrained men
Hornstrup, T., Løwenstein, F. T., Larsen, M. A., Helge, Eva Wulff, Póvoas, S., Helge, Jørn Wulff, Nielsen, Jens Jung, Fristrup, B., Andersen, J. L., Gliemann, Lasse, Nybo, Lars & Krustrup, P., 2019, In: European Journal of Applied Physiology. 119, 2, p. 561-573 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Clusters of Glycemic Response to Oral Glucose Tolerance Tests Explain Multivariate Metabolic and Anthropometric Outcomes of Bariatric Surgery in Obese Patients
Szczerbinski, L., Taylor, M. A., Citko, A., Gorska, M., Larsen, Steen, Hady, H. R. & Kretowski, A., 2019, In: Journal of Clinical Medicine. 8, 8, 16 p., 1091.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cockayne syndrome group B deficiency reduces H3K9me3 chromatin remodeler SETDB1 and exacerbates cellular aging
Lee, J., Demarest, T. G., Babbar, M., Kim, E. W., Okur, M. N., De, S., Croteau, D. L. & Bohr, Vilhelm, 2019, In: Nucleic Acids Research. 47, 16, p. 8548-8562Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Coenzyme Q10 does not improve peripheral insulin sensitivity in statin-treated men and women: the LIFESTAT study
Kuhlman, A. B., Morville, T., Dohlmann, T. L., Hansen, M., Kelly, B., Helge, Jørn Wulff & Dela, Flemming, 2019, In: Applied Physiology, Nutrition and Metabolism. 44, p. 485–492Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Copenhagen Consensus statement 2019: Physical activity and ageing
Bangsbo, J., Blackwell, J., Boraxbekk, C-J., Caserotti, P., Dela, F., Evans, A. B., Jespersen, A. P., Gliemann, L., Kramer, A. F., Lundbye-Jensen, J., Mortensen, E. L., Lassen, A. J., Gow, A. J., Harridge, S. D. R., Hellsten, Y., Kjær, M., Kujala, U. M., Rhodes, R. E., Pike, E. C. J., Skinner, T. & 6 others, , 2019, In: British Journal of Sports Medicine. 53, 14, p. 856-858 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Determination and validation of peak fat oxidation in endurance-trained men using an upper body graded exercise test
Hansen, Mikkel Thunestvedt, Rømer, Tue, Frandsen, J., Larsen, Steen, Dela, Flemming & Helge, Jørn Wulff, 2019, In: Scandinavian Journal of Medicine & Science in Sports. 29, 11, p. 1677-1690Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Diminished OPA1 expression and impaired mitochondrial morphology and homeostasis in Aprataxin-deficient cells
Zheng, Jin, Croteau, D. L., Bohr, Vilhelm & Akbari, M., 2019, In: Nucleic Acids Research. 47, 8, p. 4086–4110Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Diurnal Variation of Maximal Fat-Oxidation Rate in Trained Male Athletes
Amaro-Gahete, F. J., Jurado-Fasoli, L., Trivino, A. R., Sanchez-Delgado, G., De-la-O, A., Helge, Jørn Wulff & Ruiz, J. R., 2019, In: International Journal of Sports Physiology and Performance. 14, 8, p. 1140-1146Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Do psychosocial factors modify the negative association between disability and life satisfaction in old age?
Puvill, T., Kusumastuti, S., Lund, Rikke, Mortensen, Erik Lykke, Slaets, J., Lindenberg, J. & Westendorp, Rudi GJ, 2019, In: P L o S One. 14, 10, 15 p., e0224421.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effect of the mineralocorticoid receptor antagonist eplerenone on liver fat and metabolism in patients with type 2 diabetes: A randomized, double-blind, placebo-controlled trial (MIRAD trial)
Johansen, M. L., Schou, Morten, Rossignol, P., Holm, M. R., Rasmussen, J., Brandt, N., Frandsen, M., Chabanova, E., Dela, Flemming, Faber, Jens & Kistorp, Caroline Michaela Nervil, 2019, In: Diabetes, Obesity and Metabolism. 21, 10, p. 2305-2314 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effects of one-legged high-intensity interval training on insulin-mediated skeletal muscle glucose homeostasis in patients with type 2 diabetes
Dela, Flemming, Ingersen, Arthur, Andersen, N. B., Nielsen, M. B., Petersen, H. H. H., Hansen, C. N., Larsen, Steen, Wojtaszewski, Jørgen F P & Helge, Jørn Wulff, 2019, In: Acta Physiologica (Print). 226, 2, 18 p., e13245.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucose metabolism dysregulation affects the transcriptome of skeletal muscle and responds to three-month exercise intervention in humans
Szczerbinski, L., Niemira, M., Szczerbinski, K., Puchta, U., Taylor, M., Citko, A., Siewiec, E., Zapolska, J., Larsen, Steen, Gorska, M. & Kretowski, A., 2019, In: Diabetologia. 62, Supl. 1/SI, p. S66-S66 127.Research output: Contribution to journal › Conference abstract in journal › Research
- Published
Impact of data analysis methods for maximal fat oxidation estimation during exercise in sedentary adults Data analysis maximal fat oxidation
Amaro-Gahete, F. J., Sanchez-Delgado, G., Alcantara, J. M. A., Martinez-Tellez, B., Acosta, F. M., Helge, Jørn Wulff & Ruiz, J. R., 2019, In: European Journal of Sport Science. 19, 9, p. 1230-1239,Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Impaired mitochondrial oxidative phosphorylation capacity in epicardial adipose tissue is associated with decreased concentration of adiponectin and severity of coronary atherosclerosis
Nakajima, T., Yokota, T., Shingu, Y., Yamada, A., Iba, Y., Ujihira, K., Wakasa, S., Ooka, T., Takada, S., Shirakawa, R., Katayama, T., Furihata, T., Fukushima, A., Matsuoka, R., Nishihara, H., Dela, Flemming, Nakanishi, K., Matsui, Y. & Kinugawa, S., 2019, In: Scientific Reports. 9, 1, 3535.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Increased oxidation of RNA despite reduced mitochondrial respiration after chronic electroconvulsive stimulation of rat brain tissue
Nielsen, B., Cejvanovic, V., Wortwein, G., Hansen, A. R., Marstal, K. K., Weimann, A., Bjerring, P. N., Dela, Flemming, Poulsen, Henrik Enghusen & Jørgensen, Martin Balslev, 2019, In: Neuroscience Letters. 690, p. 1-5Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Inflammatory biomarkers in patients in Simvastatin treatment: No effect of co-enzyme Q10 supplementation
Hansen, M., Kuhlman, A. C. B., Sahl, Ronni Eg, Kelly, B., Morville, T., Dohlmann, T. L., Chrøis, K. M., Larsen, S., Helge, Jørn Wulff & Dela, Flemming, 2019, In: Cytokine. 113, p. 393-399 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Influence of exercise amount and intensity on long-term weight loss maintenance and skeletal muscle mitochondrial ROS production in humans
Larsen, Steen, Dandanell, S., Kristensen, K. B., Jorgensen, S. D., Dela, Flemming & Helge, Jørn Wulff, 2019, In: Applied Physiology, Nutrition and Metabolism. 44, 9, p. 958-964Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Lamin A/C promotes DNA base excision repair
Maynard, S., Keijzers, G., Akbari, M., Ben Ezra, Michael, Hall, A., Morevati, M., Scheibye-Knudsen, Morten, Gonzalo, S., Bartek, J. & Bohr, Vilhelm, 2019, In: Nucleic Acids Research. 47, 22, p. 11709–11728Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Low N-terminal pro-brain natriuretic peptide levels are associated with non-alcoholic fatty liver disease in patients with type 2 diabetes
Johansen, M. L., Schou, Morten, Rasmussen, J., Rossignol, P., Holm, M. R., Chabanova, E., Dela, Flemming, Faber, Jens & Kistorp, Caroline Michaela Nervil, 2019, In: Diabetes & Metabolism. 45, 5, p. 429-435Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mitochondria in the signaling pathways that control longevity and health span
Akbari, M., Kirkwood, T. B. L. & Bohr, Vilhelm, 2019, In: Ageing Research Reviews. 54, 100940.Research output: Contribution to journal › Review › Research › peer-review
- Published
Mitochondrial function in liver cells is resistant to perturbations in NAD+ salvage capacity
Dall, M., Trammell, Sam, Asping, M., Hassing, Anna Skab, Agerholm, M., Vienberg, S. G., Gillum, M. P., Larsen, Steen & Treebak, Jonas Thue, 2019, In: The Journal of Biological Chemistry. 294, 36, p. 13304-13326 23 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mitochondrial reactive oxygen species generation in blood cells is associated with disease severity and exercise intolerance in heart failure patients
Shirakawa, R., Yokota, T., Nakajima, T., Takada, S., Yamane, M., Furihata, T., Maekawa, S., Nambu, H., Katayama, T., Fukushima, A., Saito, A., Ishimori, N., Dela, Flemming, Kinugawa, S. & Anzai, T., 2019, In: Scientific Reports. 9, 8 p., 14709.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mitophagy inhibits amyloid-β and tau pathology and reverses cognitive deficits in models of Alzheimer's disease
Fang, E. F., Hou, Y., Palikaras, K., Adriaanse, B. A., Kerr, J. S., Yang, B., Lautrup, S., Hasan-Olive, M. M., Caponio, D., Dan, X., Rocktäschel, P., Croteau, D. L., Akbari, M., Greig, N. H., Fladby, T., Nilsen, H., Cader, M. Z., Mattson, M. P., Tavernarakis, N. & Bohr, Vilhelm, 2019, In: Nature Neuroscience. 22, p. 401-412Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Muscle-Saturated Bioactive Lipids Are Increased with Aging and Influenced by High-Intensity Interval Training
Søgaard, D., Baranowski, M., Larsen, Steen, Taulo Lund, M., Munk Scheuer, C., Vestergaard Abildskov, C., Greve Dideriksen, S., Dela, Flemming & Helge, Jørn Wulff, 2019, In: International Journal of Molecular Sciences . 20, 5, 1240.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
NAD+ augmentation restores mitophagy and limits accelerated aging in Werner syndrome
Fang, E. F., Hou, Y., Lautrup, S., Jensen, M. B., Yang, B., SenGupta, T., Caponio, D., Khezri, R., Demarest, T. G., Aman, Y., Figueroa, D., Morevati, M., Lee, H-J., Kato, H., Kassahun, H., Lee, J-H., Filippelli, D., Okur, M. N., Mangerich, A., Croteau, D. L. & 9 others, , 2019, In: Nature Communications. 10, 1, 18 p., 5284.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
NEIL1 stimulates neurogenesis and suppresses neuroinflammation after stress
Yang, B., Figueroa, D. M., Hou, Y., Babbar, M., Baringer, S. L., Croteau, D. L. & Bohr, Vilhelm, 2019, In: Free Radical Biology and Medicine. 141, p. 47-58 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Night shift work, long working hours and dementia: a longitudinal study of the Danish Work Environment Cohort
Nabe-Nielsen, Kirsten, Hansen, Åse Marie, Ishtiak-Ahmed, K., Brodsgaard Grynderup, M., Gyntelberg, F., Islamoska, S., Mortensen, Erik Lykke, Phung, T. K. T., Rod, Naja Hulvej, Waldemar, Gunhild, Westendorp, Rudi GJ & Garde, A. H., 2019, In: BMJ Open.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Optimizing Maximal Fat Oxidation Assessment by a Treadmill-Based Graded Exercise Protocol: When Should the Test End?
Amaro-Gahete, F. J., Sanchez-Delgado, G., Helge, Jørn Wulff & Ruiz, J. R., 2019, In: Frontiers in Physiology. 10, 5 p., 909.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Plasma free fatty acid concentration is closely tied to whole-body peak fat oxidation rate during repeated exercise
Frandsen, J., Vest, S. D., Ritz, C., Larsen, Steen, Dela, Flemming & Helge, Jørn Wulff, 2019, In: Journal of Applied Physiology. 126, 6, p. 1563-1571 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Pre-ischemic succinate dehydrogenase inhibition is protective against ischemia-reperfusion injury in rat and human myocardium with and without diabetes mellitus: [Meeting Abstract]
Jespersen, N. R., Hjortbak, M. V., Lassen, T. R., Stoettrup, N. B., Johnsen, J., Tonnesen, P. T., Larsen, Steen, Kimose, H. H. & Boetker, H. E., 2019, In: European Heart Journal. 40, S.1, p. 2101-2101 P3487 .Research output: Contribution to journal › Conference abstract in journal › Research
- Published
Subclinical thyroid dysfunction and depressive symptoms: protocol for a systematic review and individual participant data meta-analysis of prospective cohort studies
Wildisen, L., Moutzouri, E., Beglinger, S., Syrogiannouli, L., Cappola, A. R., Åsvold, B. O., Bakker, S. J. L., Ceresini, G., Dullaart, R., Ferrucci, L., Grabe, H., Jukema, J. W., Nauck, M., Trompet, S., Voelzke, H., Westendorp, R. G. J., Gussekloo, J., Peeters, R. P., Kloeppel, S., Aujesky, D. & 4 others, , 2019, In: BMJ Open. 9, 7, 4 p., 029716.Research output: Contribution to journal › Review › Research › peer-review
- Published
The influence of age and cardiorespiratory fitness on bioactive lipids in muscle
Søgaard, D., Baranowski, M., Dela, Flemming & Helge, Jørn Wulff, 2019, In: The journals of gerontology. Series A, Biological sciences and medical sciences. 74, 6, p. 778-786Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The rise of statins in Denmark: Making the case for a localized approach to the routinization of pharmaceutical prevention of cardiovascular disease
Lau, Sofie Rosenlund, Andersen, John Sahl, Dela, Flemming & Oxlund, Bjarke, 2019, In: BioSocieties. 14, 2, p. 228-250 23 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Trajectories of cardio-metabolic health in successful aging
Dela, Flemming, Finkenzeller, T., Ingersen, Arthur, Poetzelsberger, B. & Mueller, E., 2019, In: Scandinavian Journal of Medicine & Science in Sports. 29, p. 44-51Research output: Contribution to journal › Journal article › Research › peer-review
- 2018
- Published
Obesity leads to impairments in the morphology and organization of human skeletal muscle lipid droplets and mitochondrial networks, which are resolved with gastric bypass surgery-induced improvements in insulin sensitivity
Kristensen, M. D., Petersen, S. M., Møller, Kristina, Lund, Morten Asp Vonsild, Hansen, M., Hansen, C. N., Courraud, J., Helge, Jørn Wulff, Dela, Flemming & Prats Gavalda, Clara, Dec 2018, In: Acta Physiologica (Print). 224, 4, 15 p., e13100 .Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The combination of cardiorespiratory fitness and muscle strength, and mortality risk
Kim, Y., White, T., Wijndaele, K., Westgate, K., Sharp, S. J., Helge, Jørn Wulff, Wareham, N. J. & Brage, S., 1 Oct 2018, In: European Journal of Epidemiology. 33, 10, p. 953-964 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
High-intensity interval training changes mitochondrial respiratory capacity differently in adipose tissue and skeletal muscle
Dohlmann, T. L., Hindsø, M., Dela, Flemming, Helge, Jørn Wulff & Larsen, S., 1 Sep 2018, In: Physiological Reports. 6, 18, p. 1-11 e13857.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Variation in mitochondrial respiratory capacity and myosin heavy chain composition in repeated muscle biopsies
Sahl, Ronni Eg, Morville, T., Kraunsøe, R., Dela, Flemming, Helge, Jørn Wulff & Larsen, Steen, 1 Sep 2018, In: Analytical Biochemistry. 556, p. 119-124 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mitochondrial respiratory capacity remains stable despite a comprehensive and sustained increase in insulin sensitivity in obese patients undergoing gastric bypass surgery
Lund, M. T., Larsen, Steen, Hansen, M., Courraud, J., Floyd, A. K., Støckel, M., Helge, Jørn Wulff & Dela, Flemming, 1 May 2018, In: Acta Physiologica. 223, 1, p. 1-9 e13032.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
High-intensity interval training improves insulin sensitivity in older individuals
Søgaard, D., Lund, M. T., Scheuer, C. M., Dehlbaek, M. S., Dideriksen, S. G., Abildskov, C. V., Christensen, K. K., Dohlmann, T. L., Larsen, Steen, Vigelsø, A. H., Dela, Flemming & Helge, Jørn Wulff, Apr 2018, In: Acta Physiologica (Print). 222, 4, e13009.Research output: Contribution to journal › Journal article › Research › peer-review
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The relationship between skeletal muscle mitochondrial citrate synthase activity and whole body oxygen uptake adaptations in response to exercise training.
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Meal induced gut hormone secretion is altered in aerobically trained compared to sedentary young healthy males
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Two weeks of metformin treatment enhances mitochondrial respiration in skeletal muscle of AMPK kinase dead but not wild type mice
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Predicting mortality and visualizing health care spending by predicted mortality in Danes over age 65
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