Individualized Health

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  1. Published

    14-3-3 checkpoint regulatory proteins interact specifically with DNA repair protein human exonuclease 1 (hEXO1) via a semi-conserved motif

    Andersen, S. D., Keijzers, G., Rampakakis, E., Engels, K., Luhn, P., El-Shemerly, M., Nielsen, Finn Cilius, Du, Y., May, A., Bohr, Vilhelm, Ferrari, S., Zannis-Hadjopoulos, M., Fu, H. & Rasmussen, Lene Juel, Mar 2012, In: D N A Repair. 11, 3, p. 267-77 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  2. Published

    2706 km cycling in 2 weeks: effects on cardiac function in 6 elderly male athletes

    Morville, T., Rosenkilde, M., Mattsson, N., Dela, Flemming, Helge, Jørn Wulff & Rasmusen, Hanne K., 2018, In: Physician and Sportsmedicine. 46, 3, p. 263-268 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    5'-AMP activated protein kinase is involved in the regulation of myocardial ß-oxidative capacity in mice

    Stride, N., Larsen, S., Treebak, Jonas Thue, Hansen, C. N., Hey-Mogensen, M., Speerschneider, T., Jensen, Thomas Elbenhardt, Jeppesen, J., Wojtaszewski, Jørgen F P, Richter, Erik A., Køber, Lars Valeur & Dela, Flemming, 22 Feb 2012, In: Frontiers in Physiology. 3, 7 p., 00033.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    In Vitro and In Vivo Detection of Mitophagy in Human Cells, C. Elegans, and Mice

    Fang, E. F., Palikaras, K., Sun, N., Fivenson, E. M., Spangler, R. D., Kerr, J. S., Cordonnier, S. A., Hou, Y., Dombi, E., Kassahun, H., Tavernarakis, N., Poulton, J., Nilsen, H. & Bohr, Vilhelm, 2017, In: Journal of Visualized Experiments. 129, e56301.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Rev1 deficiency induces a metabolic shift in MEFs that can be manipulated by the NAD+ precursor nicotinamide riboside

    Anugula, Sharath, Li, Zhiquan, Li, Yuan, Hendriksen, A., Christensen, P. B., Wang, L., Monk, J. M., de Wind, N., Bohr, Vilhelm, Desler, Claus, Naviaux, R. K. & Rasmussen, Lene Juel, 2023, In: Heliyon. 9, 6, e17392.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    A Biological Age Model Designed for Health Promotion Interventions: Protocol for an Interdisciplinary Study for Model Development

    Husted, Karina Louise Skov, Fogelstrom, M., Hulst, P., Brink-Kjaer, A., Henneberg, K., Sorensen, H. B. D., Dela, Flemming & Helge, Jørn Wulff, 2020, In: JMIR Research Protocols. 9, 10, 13 p., 19209.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    A Model for Estimating Biological Age From Physiological Biomarkers of Healthy Aging: Cross-sectional Study

    Husted, Karina Louise Skov, Brink-Kjaer, A., Fogelstrom, M., Hulst, P., Bleibach, A., Henneberg, K., Sorensen, H. B. D., Dela, Flemming, Jacobsen, Jens Christian Brings & Helge, Jørn Wulff, 2022, In: JMIR Aging. 5, 2, 15 p., 35696.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    A Small Molecule Inhibitor of the BLM Helicase Modulates Chromosome Stability in Human Cells

    Nguyen, G. H., Dexheimer, T. S., Rosenthal, A. S., Chu, W. K., Singh, D. K., Mosedale, G., Bachrati, C. Z., Schultz, L., Sakurai, M., Savitsky, P., Abu, M., McHugh, P. J., Bohr, Vilhelm, Harris, C. C., Jadhav, A., Gileadi, O., Maloney, D. J., Simeonov, A. & Hickson, Ian David, 24 Jan 2013, In: Chemistry & Biology. 20, 1, p. 55-62 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    A high carbohydrate diet remains the evidence based choice for elite athletes to optimise performance

    Helge, Jørn Wulff, 1 May 2017, In: Journal of Physiology. 595, 9, p. 2775-2775

    Research output: Contribution to journal › Comment/debate › Research › peer-review

  10. Published

    A high-fat diet and NAD+ activate sirt1 to rescue premature aging in cockayne syndrome

    Scheibye-Knudsen, M., Mitchell, S. J., Fang, E. F., Iyama, T., Ward, T., Wang, J., Dunn, C. A., Singh, N., Veith, S., Hasan-Olive, M. M., Mangerich, A., Wilson, M. A., Mattson, M. P., Bergersen, L. H., Cogger, V. C., Warren, A., Le Couteur, D. G., Moaddel, R., Wilson, D. M., Croteau, D. L. & 2 others, De Cabo, R. & Bohr, Vilhelm, 4 Nov 2014, In: Cell Metabolism. 20, 5, p. 840-855 16 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    A ketogenic diet accelerates neurodegeneration in mice with induced mitochondrial DNA toxicity in the forebrain

    Lauritzen, K. H., Hasan-Olive, M. M., Regnell, C. E., Kleppa, L., Scheibye-Knudsen, Morten, Gjedde, Albert, Klungland, A., Bohr, Vilhelm, Storm-Mathisen, J. & Bergersen, L. H., Dec 2016, In: Neurobiology of Aging. 48, p. 34-47

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    A maximal cycle test with good validity and high repeatability in adults of all ages

    Eriksen, L., Tolstrup, J. S., Larsen, Steen, Grønbæk, M. & Helge, Jørn Wulff, Dec 2014, In: International Journal of Sports Medicine. 35, 14, p. 1184-9 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    A novel method for determining human ex vivo submaximal skeletal muscle mitochondrial function

    Hey-Mogensen, M., Gram, M., Jensen, M. B., Lund, M. T., Hansen, C. N., Scheibye-Knudsen, Morten, Bohr, Vilhelm & Dela, Flemming, 1 Sep 2015, In: The Journal of Physiology. 593, 17, p. 3991-4010 20 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    A randomized double-blind study of testosterone replacement therapy or placebo in testicular cancer survivors with mild Leydig cell insufficiency (Einstein-intervention)

    Bandak, M., Jørgensen, N., Juul, Anders, Lauritsen, J., Kreiberg, M., Oturai, P. S., Helge, Jørn Wulff & Daugaard, G., 3 Jul 2017, In: B M C Cancer. 17, 8 p., 461.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    ADAMTS9 regulates skeletal muscle insulin sensitivity through extracellular matrix alterations

    Graae, A-S., Grarup, N., Ribel-Madsen, R., Lystbæk, S. H., Boesgaard, T., Staiger, H., Fritsche, A., Wellner, N., Sulek, K., Kjølby, M. F., Backe, M. B., Chubanava, S., Prats, C., Serup, A. K. L., Birk, J. B., Dubail, J., Gillberg, L., Vienberg, S. G., Nykjær, A., Kiens, B. & 10 others, Wojtaszewski, Jørgen F P, Larsen, Steen, Apte, S. S., Häring, H., Vaag, A., Zethelius, B., Pedersen, Oluf Borbye, Treebak, Jonas Thue, Hansen, Torben & Holst, Birgitte, 2019, In: Diabetes. 68, 3, p. 502-514

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Absent Exercise-Induced Improvements in Fat Oxidation in Women With Polycystic Ovary Syndrome After High-Intensity Interval Training

    Lionett, S., Kiel, I. A., Røsbjørgen, R., Lydersen, S., Larsen, Steen & Moholdt, T., 2021, In: Frontiers in Physiology. 12, 13 p., 649794.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Accelerated progression of white matter hyperintensities and subsequent risk of mortality: a 12-year follow-up study

    Sabayan, B., van der Grond, J., Westendorp, Rudi GJ, van Buchem, M. A. & de Craen, A. J. M., Jun 2015, In: Neurobiology of Aging. 36, 6, p. 2130–2135 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Accuracy of Continuous Glucose Monitoring Measurements in Normo-Glycemic Individuals

    Akintola, A. A., Noordam, R., Jansen, S. W., de Craen, A. J., Ballieux, B. E., Cobbaert, C. M., Mooijaart, S. P., Pijl, H., Westendorp, Rudi GJ & van Heemst, D., 7 Oct 2015, In: PloS one. 10, 10, p. 1-13 13 p., e0139973.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Accuracy of a Clinical Applicable Method for Prediction of VO2max Using Seismocardiography

    Hansen, Mikkel Thunestvedt, Husted, Karina Louise Skov, Fogelstrøm, M., Rømer, Tue, Schmidt, S. E., Sørensen, K. & Helge, Jørn Wulff, 2023, In: International Journal of Sports Medicine. 44, 9, p. 650-656

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Acetaminophen toxicity induces mitochondrial complex I inhibition in human liver tissue

    Chrøis, K. M., Larsen, Steen, Pedersen, J. S., Rygg, M. O., Boilsen, A. E. B., Bendtsen, Flemming & Dela, Flemming, 2020, In: Basic & Clinical Pharmacology & Toxicology. 126, 1, p. 86-91

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Acquired Localized Cutis Laxa due to Increased Elastin Turnover

    Nygaard, R. H., Maynard, S., Schjerling, P., Kjær, M., Qvortrup, Klaus, Bohr, Vilhelm, Rasmussen, Lene Juel, Jemec, Gregor & Heidenheim, M., 14 Jun 2016, In: Case Reports in Dermatology. 8, 1, p. 42-51 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Actovegin, a non-prohibited drug increases oxidative capacity in human skeletal muscle

    Søndergård, S. D., Dela, Flemming, Helge, Jørn Wulff & Larsen, Steen, Oct 2016, In: European Journal of Sport Science. 16, 7, p. 801-807 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Acute exercise improves motor memory: Exploring potential biomarkers

    Skriver, K. C., Roig, M., Lundbye-Jensen, Jesper, Pingel, Jessica, Helge, Jørn Wulff, Kiens, Bente & Nielsen, Jens Bo, 2014, In: Neurobiology of Learning and Memory. 116, p. 46-58 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Adipocyte size and cellular expression of caveolar proteins analyzed by confocal microscopy.

    Hulstrøm, V., Prats Gavalda, Clara & Vinten, J., 15 Jun 2013, In: American Journal of Physiology: Cell Physiology. 304, 12, p. C1168-75 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Adipose tissue mitochondrial respiration and lipolysis before and after a weight loss by diet and RYGB

    Hansen, M., Lund, M. T., Gregers, E., Kraunsøe, R., van Hall, Gerrit, Helge, Jørn Wulff & Dela, Flemming, Oct 2015, In: Obesity. 23, 10, p. 2022-2229 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    Adverse Metabolic Risk Profiles in Greenlandic Inuit Children Compared to Danish Children

    Munch-Andersen, T., Sorensen, K., Andersen, L. B., Aachmann-Andersen, N. J., Aksglaede, L., Juul, A. & Helge, Jørn Wulff, Jun 2013, In: Obesity. 21, 6, p. 1226-1231 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    Aerobic Exercise Performance and Muscle Strength in Statin Users-The LIFESTAT Study

    Morville, T., Dohlmann, T. L., Kuhlman, A. B., Sahl, Ronni Eg, Kriegbaum, Margit, Larsen, Steen, Dela, Flemming & Helge, Jørn Wulff, 2019, In: Medicine and Science in Sports and Exercise. 51, 7, p. 1429-1437 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    Aerobic Exercise Training Increases Muscle Water Content in Obese Middle-Age Men

    Mora-Rodríguez, R., Sanchez-Roncero, A., Fernández-Elías, V. E., Guadalupe-Grau, A., Ortega, J. F., Dela, Flemming & Helge, Jørn Wulff, May 2016, In: Medicine and Science in Sports and Exercise. 48, 5, p. 822-828 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    Aerobic and resistance exercise training reverses age-dependent decline in NAD(+) salvage capacity in human skeletal muscle

    de Guia, R. M., Agerholm, M., Nielsen, Thomas Svava, Consitt, L. A., Sogaard, D., Helge, Jørn Wulff, Larsen, Steen, Brandauer, J., Houmard, J. A. & Treebak, Jonas Thue, 2019, In: Physiological Reports. 7, 12, 15 p., e14139.

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    Age- and Functional Status-Dependent Association Between Blood Pressure and Cognition: The Milan Geriatrics 75+ Cohort Study

    Ogliari, G., Sabayan, B., Mari, D., Rossi, P. D., Lucchi, T. A., de Craen, A. J. M. & Westendorp, Rudi GJ, Sep 2015, In: Journal of the American Geriatrics Society. 63, 9, p. 1741-1748 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Published

    Age-related macular degeneration: A two-level model hypothesis

    Rozing, Maarten Pieter, Durhuus, J. A., Krogh Nielsen, M., Subhi, Y., Kirkwood, T. B. L., Westendorp, Rudi GJ & Sørensen, Torben Lykke, 2020, In: Progress in Retinal and Eye Research. 76, 100825.

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. Published

    Aging in high functioning elderly persons: study design and analyses of behavioral and psychological factors

    Finkenzeller, T., Poetzelsberger, B., Koesters, A., Wuerth, S., Amesberger, G., Dela, Flemming & Mueller, E., 2019, In: Scandinavian Journal of Medicine & Science in Sports. 29, p. 7-16

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. Published

    Aging, longevity and health

    Rasmussen, Lene Juel, Sander, M., Wewer, Ulla M. & Bohr, Vilhelm, 23 Jul 2011, In: Mechanisms of Ageing and Development. p. 522-32 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Published

    Akt and Rac1 signalling are jointly required for insulin-stimulated glucose uptake in skeletal muscle and downregulated in insulin resistance

    Sylow, Lykke, Kleinert, Maximilian, Pehmøller, C., Prats Gavalda, Clara, Chiu, T. T., Klip, A., Richter, Erik A. & Jensen, Thomas Elbenhardt, 2014, In: Cellular Signalling. 26, 2, p. 323-331 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. Published

    Alpine Skiing With total knee ArthroPlasty (ASWAP): metabolism, inflammation, and skeletal muscle fiber characteristics

    Kristensen, M., Pötzelsberger, B., Scheiber, P., Bergdahl, A., Hansen, C. N., Andersen, J. L., Narici, M., Salvioli, S., Conte, M., Müller, E. & Dela, Flemming, Aug 2015, In: Scandinavian Journal of Medicine & Science in Sports. 25, Supplement S2, p. 40-48 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    Alpine Skiing With total knee ArthroPlasty (ASWAP): study design and intervention

    Koesters, A., Poetzelsberger, B., Dela, Flemming, Dorn, U., Hofstaedter, T., Fink, C. & Mueller, E., Aug 2015, In: Scandinavian Journal of Medicine & Science in Sports. 25, Supplement S2, p. 3-9 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Published

    Alteration of mitochondrial homeostasis is an early event in a C. elegans model of human tauopathy

    Palikaras, K., Achanta, K., Choi, S., Akbari, M. & Bohr, Vilhelm, 2021, In: Aging. 13, 21, p. 23876-23894 19 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. Published

    Altered cardiovascular risk pattern of LDL cholesterol in older adults

    Rozing, Maarten Pieter & Westendorp, Rudi GJ, 2023, In: Current Opinion in Lipidology. 34, 1, p. 22-26 5 p.

    Research output: Contribution to journal › Review › Research › peer-review

  39. Published

    Altered mitochondrial regulation in quadriceps muscles of patients with COPD

    Naimi, A. I., Bourbeau, J., Perrault, H., Baril, J., Wright-Paradis, C., Rossi, A., Taivassalo, T., Sheel, A. W., Rabøl, R., Dela, Flemming & Boushel, R. C., 2011, In: Clinical Physiology and Functional Imaging. 31, 2, p. 124-31 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  40. Published

    An Emerging Epidemic of Noncommunicable Diseases in Developing Populations Due to a Triple Evolutionary Mismatch

    Koopman, J. J. E., van Bodegom, D., Ziem, J. B. & Westendorp, Rudi GJ, Jun 2016, In: American Journal of Tropical Medicine and Hygiene. 94, 6, p. 1189-1192 4 p.

    Research output: Contribution to journal › Comment/debate › Research › peer-review

  41. Published

    An Internet-Based Physical Activity Intervention to Improve Quality of Life of Inactive Older Adults: A Randomized Controlled Trial

    Broekhuizen, K., de Gelder, J., Wijsman, C. A., Wijsman, L. W., Westendorp, Rudi GJ, Verhagen, E., Slagboom, P. E., de Craen, A. J., van Mechelen, W., van Heemst, D., van der Ouderaa, F. & Mooijaart, S. P., Apr 2016, In: Journal of Medical Internet Research. 18, 4, p. 1-11 11 p., e74.

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. Published

    An analysis of the productivity and impact of clinical PhD theses from the University of Copenhagen

    Rømer, Tue, Hansen, Mikkel Thunestvedt & Helge, Jørn Wulff, 2020, In: Danish Medical Journal. 67, 5, A12190731.

    Research output: Contribution to journal › Journal article › Research › peer-review

  43. Published

    An in vivo study on brain microstructure in biological and chronological ageing

    Altmann-Schneider, I., de Craen, A. J. M., van den Berg-Huysmans, A. A., Slagboom, P., Westendorp, Rudi GJ, van Buchem, M. A. & van der Grond, J., 25 Mar 2015, In: PloS one. 10, 3, p. 1-12 12 p., e0120778.

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Published

    An individual participant data analysis of prospective cohort studies on the association between subclinical thyroid dysfunction and depressive symptoms

    Wildisen, L., Del Giovane, C., Moutzouri, E., Beglinger, S., Syrogiannouli, L., Collet, T-H., Cappola, A. R., Asvold, B. O., Bakker, S. J. L., Yeap, B. B., Almeida, O. P., Ceresini, G., Dullaart, R. P. F., Ferrucci, L., Grabe, H., Jukema, J. W., Nauck, M., Trompet, S., Voelzke, H., Westendorp, R. & 7 others, Gussekloo, J., Kloppel, S., Aujesky, D., Bauer, D., Peeters, R., Feller, M. & Rodondi, N., 2020, In: Scientific Reports. 10, 1, 12 p., 19111.

    Research output: Contribution to journal › Journal article › Research › peer-review

  45. Published

    An optimized histochemical method to assess skeletal muscle glycogen and lipid stores reveals two metabolically distinct populations of type I muscle fibers

    Prats Gavalda, Clara, Gomez-Cabello, A., Nordby, P., Andersen, J. L., Helge, Jørn Wulff, Dela, Flemming, Baba, O. & Ploug, Thorkil, 2013, In: PloS one. 8, 10, p. e77774 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  46. Published

    Angiotensin-Converting Enzyme 2 (SARS-CoV-2 receptor) expression in human skeletal muscle

    Perez-Valera, M., Martinez-Canton, M., Gallego-Selles, A., Galván-Alvarez, V., Gelabert-Rebato, M., Morales-Alamo, D., Santana, A., Martin-Rodriguez, S., Ponce-Gonzalez, J. G., Larsen, S., Losa-Reyna, J., Perez-Suarez, I., Dorado, C., Curtelin, D., Gonzalez-Henriquez, J. J., Boushel, R., Hallen, J., de Pablos Velasco, P., Freixinet-Gilart, J., Holmberg, H. C. & 3 others, Helge, Jørn Wulff, Martin-Rincon, M. & Calbet, J. A. L., 2021, In: Scandinavian Journal of Medicine and Science in Sports. 31, 12, p. 2249-2258 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. Published

    Angiotensin-converting enzyme activity and cognitive impairment during hypoglycaemia in healthy humans

    Pedersen-Bjergaard, Ulrik, Thomsen, Carsten Eckhart, Høgenhaven, H., Smed, A., Kjaer, T. W., Holst, Jens Juul, Dela, Flemming, Hilsted, Linda, Frandsen, E., Pramming, S. & Thorsteinsson, B., 2008, In: Journal of the Renin-Angiotensin-Aldosterone System. 9, 1, p. 37-48 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  48. Published

    Anthropometry, DXA and leptin reflect subcutaneous but not visceral abdominal adipose tissue by MRI in 197 healthy adolescents

    Tinggaard, J., Hagen, C. P., Christensen, A. N., Mouritsen, A., Mieritz, M. G., Wohlfahrt-Veje, C., Helge, Jørn Wulff, Beck, T. N., Fallentin, E., Larsen, R., Jensen, R. B., Juul, Anders & Main, Katharina Maria, 2017, In: Pediatric Research. 82, p. 620-628

    Research output: Contribution to journal › Journal article › Research › peer-review

  49. Published

    Antioxidant enzymes and Nrf2/Keap1 in human skeletal muscle: Influence of age, sex, adiposity and aerobic fitness

    Galvan-Alvarez, V., Gallego-Selles, A., Martinez-Canton, M., García-Gonzalez, E., Gelabert-Rebato, M., Ponce-Gonzalez, J. G., Larsen, Steen, Morales-Alamo, D., Losa-Reyna, J., Perez-Suarez, I., Dorado, C., Perez-Valera, M., Holmberg, H. C., Boushel, R., de Pablos Velasco, P., Helge, Jørn Wulff, Martin-Rincon, M. & Calbet, J. A. L., 2023, In: Free Radical Biology and Medicine. 209, p. 282-291 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  50. Published

    Aprataxin localizes to mitochondria and preserves mitochondrial function

    Sykora, P., Croteau, D. L., Bohr, Vilhelm & Wilson, D. M., 3 May 2011, In: Proceedings of the National Academy of Sciences USA (PNAS). 108, 18, p. 7437-42 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

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