Individualized Health

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  1. 2021
  2. Published

    Atorvastatin impairs liver mitochondrial function in obese Göttingen Minipigs but heart and skeletal muscle are not affected

    Christiansen, L. B., Dohlmann, T. L., Ludvigsen, T. P., Parfieniuk, E., Ciborowski, M., Szczerbinski, L., Kretowski, A., Desler, Claus, Tiano, L., Orlando, P., Martinussen, Torben, Olsen, Lisbeth Høier & Larsen, Steen, 2021, In: Scientific Reports. 11, 15 p., 2167.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Base excision repair causes age-dependent accumulation of single-stranded DNA breaks that contribute to Parkinson disease pathology

    SenGupta, T., Palikaras, K., Esbensen, Y. Q., Konstantinidis, G., Galindo, F. J. N., Achanta, K., Kassahun, H., Stavgiannoudaki, I., Bohr, Vilhelm, Akbari, M., Gaare, J., Tzoulis, C., Tavernarakis, N. & Nilsen, H., 2021, In: Cell Reports. 36, 10, 109668.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    CDK2 phosphorylation of Werner protein (WRN) contributes to WRN’s DNA double-strand break repair pathway choice

    Lee, J. H., Shamanna, R. A., Kulikowicz, T., Fakouri, N. B., Kim, E. W., Christiansen, L. S., Croteau, D. L. & Bohr, Vilhelm, 2021, In: Aging Cell. 20, 11, 14 p., e13484.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Cytosolic self-DNA—A potential source of chronic inflammation in aging

    Akbari, M., Shanley, D. P., Bohr, Vilhelm & Rasmussen, Lene Juel, 2021, In: Cells. 10, 12, 3544.

    Research output: Contribution to journal › Review › Research › peer-review

  6. Published

    Depleted myocardial coenzyme Q10 in cavalier king charles spaniels with congestive heart failure due to myxomatous mitral valve disease

    Christiansen, L. B., Reimann, Maria Josefine, Schou-Pedersen, A. M. V., Larsen, Steen, Lykkesfeldt, Jens & Olsen, Lisbeth Høier, 2021, In: Antioxidants. 10, 2, p. 1-13 13 p., 161.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    EX-vivo whole blood stimulation with A2E does not elicit an inflammatory cytokine response in patients with age-related macular degeneration

    Durhuus, J. A., Rozing, Maarten Pieter, Nielsen, M. K., Molbech, C. R., Keijzers, G., Scheibye-Knudsen, Morten, Rasmussen, Lene Juel, Westendorp, Rudi GJ & Sørensen, Torben Lykke, 2021, In: Scientific Reports. 11, 1, 8226.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Effect of Levothyroxine Therapy on the Development of Depressive Symptoms in Older Adults With Subclinical Hypothyroidism An Ancillary Study of a Randomized Clinical Trial

    Wildisen, L., Feller, M., Del Giovane, C., Moutzouri, E., Du Puy, R. S., Mooijaart, S. P., Collet, T., Poortvliet, R. K. E., Kearney, P., Quinn, T. J., Kloppel, S., Bauer, D. C., Peeters, R. P., Westendorp, Rudi GJ, Aujesky, D., Gussekloo, J. & Rodondi, N., 2021, In: JAMA network open. 4, 2, 12 p., 2036645.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Effects of football fitness training on lymphedema and upper-extremity function in women after treatment for breast cancer: A randomized trial

    Bloomquist, K., Krustrup, P., Fristrup, B., Sørensen, V., Helge, Jørn Wulff, Helge, Eva Wulff, Soelberg Vadstrup, E., Rørth, M., Hayes, S. C. & Uth, J., 2021, In: Acta Oncologica. 60, 3, p. 392-400 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Endotrophin is associated with chronic multimorbidity and all-cause mortality in a cohort of elderly women

    Staunstrup, L. M., Bager, C. L., Frederiksen, P., Helge, Jørn Wulff, Brunak, Søren, Christiansen, C. & Karsdal, M., 2021, In: EBioMedicine. 68, 10 p., 103391.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Familial longevity is associated with lower baseline bone turnover but not differences in bone turnover in response to rhTSH

    Zutinic, A., Roelfsema, F., Pijl, H., Ballieux, B. E., Westendorp, Rudi GJ, Blauw, G. J. & van Heemst, D., 2021, In: Aging. 13, 17, p. 21029-21039 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    High bone mineral density in lifelong trained female team handball players and young elite football players

    Hagman, M., Helge, Eva Wulff, Fristrup, B., Jørgensen, Niklas Rye, Helge, Jørn Wulff & Krustrup, P., 2021, In: European Journal of Applied Physiology. 121, 10, p. 2825-2836 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Maximal fat oxidation rate is higher in fit women and unfit women with obesity, compared to normal weight unfit women

    Frandsen, J., Hansen, I. M. D., Wismann, J. F., Olsen, M. H., Brage-Andersen, M. R., Sahl, Ronni Eg, Hansen, M., Ingersen, Arthur, Modvig, J. L., Schmücker, M., brl298, brl298, Dela, Flemming, Larsen, Steen & Helge, Jørn Wulff, 2021, In: Journal of Clinical Endocrinology and Metabolism. 106, 11, p. E4389-E4399 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Metabolomic Profile of Skeletal Muscle and Its Change Under a Mixed-Mode Exercise Intervention in Progressively Dysglycemic Subjects

    Szczerbinski, L., Golonko, A., Taylor, M., Puchta, U., Konopka, P., Paszko, A., Citko, A., Szczerbinski, K., Gorska, M., Zabielski, P., Błachnio-Zabielska, A., Larsen, Steen & Kretowski, A., 2021, In: Frontiers in Endocrinology. 12, 13 p., 778442.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    NAD+ supplementation reduces neuroinflammation and cell senescence in a transgenic mouse model of Alzheimer's disease via cGAS-STING

    Hou, Y., Wei, Y., Lautrup, S., Yang, B., Wang, Y., Cordonnier, S., Mattson, M. P., Croteau, D. L. & Bohr, Vilhelm, 2021, In: Proceedings of the National Academy of Sciences of the United States of America. 118, 37, e2011226118.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Olfactory dysfunction in aging and neurodegenerative diseases

    Dan, X., Wechter, N., Gray, S., Mohanty, J. G., Croteau, D. L. & Bohr, Vilhelm, 2021, In: Ageing Research Reviews. 70, 101416.

    Research output: Contribution to journal › Review › Research › peer-review

  17. Published

    One year of Football Fitness improves L1-L4 BMD, postural balance and muscle strength in women treated for breast cancer

    Uth, J., Fristrup, B., Sørensen, V., Helge, Eva Wulff, Christensen, M. K., Kjærgaard, J. B., Møller, T. K., Helge, Jørn Wulff, Jørgensen, Niklas Rye, Rørth, M., Vadstrup, E. S. & Krustrup, P., 2021, In: Scandinavian Journal of Medicine & Science in Sports. 31, 7, p. 1545-1557 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Peak fat oxidation rate is closely associated with plasma free fatty acid concentrations in women; similar to men

    Frandsen, J., Poggi, A. I., Ritz, C., Larsen, S., Dela, Flemming & Helge, Jørn Wulff, 2021, In: Frontiers in Physiology. 12, 11 p., 696261.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Pharmacological but not physiological GDF15 suppresses feeding and the motivation to exercise

    Klein, A. B., Nicolaisen, T. S., Ørtenblad, N., Gejl, K. D., Jensen, R., Fritzen, A. M., Larsen, E. L., Karstoft, K., Poulsen, H. E., Morville, T., Sahl, R. E., Helge, J. W., Lund, J., Falk, S., Lyngbæk, M., Ellingsgaard, H., Pedersen, B. K., Lu, W., Finan, B., Jørgensen, S. B. & 5 others, Seeley, R. J., Kleinert, Maximilian, Kiens, Bente, Richter, Erik A. & Clemmensen, Christoffer, 2021, In: Nature Communications. 12, 9 p., 1041.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Reliability and variation in mitochondrial respiration in human adipose tissue

    Sahl, Ronni Eg, Høy Helms, E. F., Schmücker, Malte, Flensted-Jensen, Mathias, Ingersen, Arthur, Morville, T., Dela, Flemming, Helge, Jørn Wulff & Larsen, S., 2021, In: Adipocytes. 10, 1, p. 605-611 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Six weeks of high intensity cycle training reduces H2O2 emission and increases antioxidant protein levels in obese adults with risk factors for type 2 diabetes

    Flensted-Jensen, Mathias, Gram, M., Dela, Flemming, Helge, Jørn Wulff & Larsen, Steen, 2021, In: Free Radical Biology & Medicine. 173, p. 1-6

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    The effects of 3 weeks of oral glutathione supplementation on whole body insulin sensitivity in obese males with and without type 2 diabetes: a randomized trial

    Søndergård, S. D., Cintin, I., Kuhlman, A. B., Morville, T. H., Bergmann, M. L., Kjær, L. K., Poulsen, Henrik Enghusen, Giustarini, D., Rossi, R., Dela, Flemming, Helge, Jørn Wulff & Larsen, S., 2021, In: Applied Physiology, Nutrition and Metabolism. 46, 9, 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    The influence of age, sex and cardiorespiratory fitness on maximal fat oxidation rate

    Frandsen, J., Amaro-Gahete, F. J., Landgrebe, A., Dela, Flemming, Ruiz, J. R., Helge, Jørn Wulff & Larsen, Steen, 2021, In: Applied Physiology, Nutrition and Metabolism. 46, 10, p. 1241-1247

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    The response of mitochondrial respiration and quantity in skeletal muscle and adipose tissue to exercise in humans with prediabetes

    Szczerbinski, L., Taylor, M. A., Puchta, U., Konopka, P., Paszko, A., Citko, A., Szczerbinski, K., Goscik, J., Gorska, M., Larsen, Steen & Kretowski, A., 2021, In: Cells. 10, 11, 3013.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    The training induced increase in whole-body peak fat oxidation rate may be attenuated with aging

    Frandsen, J., Beck, T., Langkilde, C. H., Larsen, Steen, Dela, Flemming & Helge, Jørn Wulff, 2021, In: European Journal of Sport Science. 21, 1, p. 69-76

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    Tipping Points-Do the Prognostic Values of Multimorbidity and Functional Status Vary with Age?

    Thygesen, L. C., Christensen, K., Rorth, M., Sørensen, H. T., Vandenbroucke, J. P. & Westendorp, Rudi GJ, 2021, In: Clinical Epidemiology. 13, p. 853-857 5 p.

    Research output: Contribution to journal › Editorial › Research › peer-review

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