- 2013
- Published
Rac1 signaling is required for insulin-stimulated glucose uptake and is dysregulated in insulin-resistant murine and human skeletal muscle
Sylow, Lykke, Jensen, Thomas Elbenhardt, Kleinert, Maximilian, Højlund, K., Kiens, Bente, Wojtaszewski, Jørgen F P, Prats Gavalda, Clara, Schjerling, P. & Richter, Erik A., 2013, In: Diabetes. 62, 6, p. 1865-1875 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Subcellular localization and mechanism of secretion of vascular endothelial growth factor in human skeletal muscle
Høier, B., Prats Gavalda, Clara, Qvortrup, Klaus, Pilegaard, Henriette, Bangsbo, Jens & Hellsten, Ylva, 2013, In: F A S E B Journal. 27, 9, p. 3496-3504 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Two weeks of metformin treatment enhances mitochondrial respiration in skeletal muscle of AMPK kinase dead but not wild type mice
Kristensen, Jonas Møller, Larsen, Steen, Helge, Jørn Wulff, Dela, Flemming & Wojtaszewski, Jørgen F P, 2013, In: P L o S One. 8, 1, 10 p., e53533.Research output: Contribution to journal › Journal article › Research › peer-review
- 2012
- Published
The helicase and ATPase activities of RECQL4 are compromised by mutations reported in three human patients
Jensen, M. B., Dunn, C. A., Keijzers, G., Kulikowicz, T., Rasmussen, Lene Juel, Croteau, D. L. & Bohr, Vilhelm, Nov 2012, In: Aging. 4, 11, p. 790-802 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Høj puls og masser af fedt
Christensen, Dirk Lund & Helge, Jørn Wulff, 15 Jun 2012, In: Weekendavisen. 24, p. 11 1 p.Research output: Contribution to journal › Contribution to newspaper - Newspaper article › Communication
- Published
Cockayne syndrome group B protein prevents the accumulation of damaged mitochondria by promoting mitochondrial autophagy
Scheibye-Knudsen, M., Ramamoorthy, M., Sykora, P., Maynard, S., Lin, P., Minor, R. K., Wilson, D. M., Cooper, M., Spencer, R., de Cabo, R., Croteau, D. L. & Bohr, Vilhelm, Apr 2012, In: The Journal of Experimental Medicine. 209, 4, p. 855-69 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
14-3-3 checkpoint regulatory proteins interact specifically with DNA repair protein human exonuclease 1 (hEXO1) via a semi-conserved motif
Andersen, S. D., Keijzers, G., Rampakakis, E., Engels, K., Luhn, P., El-Shemerly, M., Nielsen, Finn Cilius, Du, Y., May, A., Bohr, Vilhelm, Ferrari, S., Zannis-Hadjopoulos, M., Fu, H. & Rasmussen, Lene Juel, Mar 2012, In: D N A Repair. 11, 3, p. 267-77 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Metabolic profile in two physically active Inuit groups consuming either a western or a traditional Inuit diet
Munch-Andersen, T., Olsen, D. B., Søndergaard, H., Daugaard, J. R., Bysted, A., Christensen, Dirk Lund, Saltin, B. & Helge, Jørn Wulff, Mar 2012, In: International Journal of Circumpolar Health. 71, 8 p., 17342.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
5'-AMP activated protein kinase is involved in the regulation of myocardial ß-oxidative capacity in mice
Stride, N., Larsen, S., Treebak, Jonas Thue, Hansen, C. N., Hey-Mogensen, M., Speerschneider, T., Jensen, Thomas Elbenhardt, Jeppesen, J., Wojtaszewski, Jørgen F P, Richter, Erik A., Køber, Lars Valeur & Dela, Flemming, 22 Feb 2012, In: Frontiers in Physiology. 3, 7 p., 00033.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Endurance training per se increases metabolic health in young, moderately overweight men
Nordby, P., Auerbach, P. L., Rosenkilde, M., Kristiansen, L., Thomasen, J. R., Rygaard, L., Groth, R., Brandt, N., Helge, Jørn Wulff, Richter, Erik A., Ploug, Thorkil & Stallknecht, Bente Merete, 2012, In: Obesity. 20, 11, p. 2202-2212 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Muscle ceramide content is similar after 3 weeks' consumption of fat or carbohydrate diet in a crossover design in patients with type 2 diabetes
Helge, Jørn Wulff, Tobin, L., Drachmann, T., Hellgren, L., Dela, Flemming & Galbo, Henrik, 2012, In: European Journal of Applied Physiology. 112, 3, p. 911-918Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Muscle inflammatory signaling in response to 9 days of physical inactivity in young men with low compared to normal birth weight
Friedrichsen, M., Ribel-Madsen, R., Mortensen, B., Hansen, C. N., Alibegovic, A. C., Højbjerre, L., Sonne, M. P., Wojtaszewski, Jørgen F P, Stallknecht, Bente Merete, Dela, Flemming & Vaag, Allan, 2012, In: European Journal of Endocrinology. 167, 6, p. 829-838 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
RECQL4 localizes to mitochondria and preserves mitochondrial DNA integrity
Croteau, D. L., Rossi, M. L., Canugovi, C., Tian, J., Sykora, P., Ramamoorthy, M., Wang, Z. M., Singh, D. K., Akbari, M., Kasiviswanathan, R., Copeland, W. C. & Bohr, Vilhelm, 2012, In: Aging Cell. 11, 3, p. 456-66 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Skeletal muscle mitochondrial respiration in AMPKa2 kinase dead mice
Larsen, S., Kristensen, Jonas Møller, Stride, N., Wojtaszewski, Jørgen F P, Helge, Jørn Wulff & Dela, Flemming, 2012, In: Acta Physiologica (Print). 205, 2, p. 314-320 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2011
- Published
Aging, longevity and health
Rasmussen, Lene Juel, Sander, M., Wewer, Ulla M. & Bohr, Vilhelm, 23 Jul 2011, In: Mechanisms of Ageing and Development. p. 522-32 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Negative Regulation of STAT3 Protein-mediated Cellular Respiration by SIRT1 Protein
Bernier, M., Paul, R. K., Martin-Montalvo, A., Scheibye-Knudsen, M., Song, S., He, H., Armour, S. M., Hubbard, B. P., Bohr, Vilhelm, Wang, L., Zong, Y., Sinclair, D. A. & de Cabo, R., 3 Jun 2011, In: The Journal of Biological Chemistry. 286, 22, p. 19270-9 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Aprataxin localizes to mitochondria and preserves mitochondrial function
Sykora, P., Croteau, D. L., Bohr, Vilhelm & Wilson, D. M., 3 May 2011, In: Proceedings of the National Academy of Sciences USA (PNAS). 108, 18, p. 7437-42 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
DNA repair deficiency in neurodegeneration
Jeppesen, D. K., Bohr, Vilhelm & Stevnsner, T. V., 30 Apr 2011, In: Progress in Neurobiology. 94, 2, p. 166-200 35 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Non-B DNA-forming sequences and WRN deficiency independently increase the frequency of base substitution in human cells
Bacolla, A., Wang, G., Jain, A., Chuzhanova, N. A., Cer, R. Z., Collins, J. R., Cooper, D. N., Bohr, Vilhelm & Vasquez, K. M., 25 Mar 2011, In: The Journal of Biological Chemistry. 286, 12, p. 10017-26 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Proteome-wide identification of WRN-interacting proteins in untreated and nuclease-treated samples
Lachapelle, S., Gagné, J., Garand, C., Desbiens, M., Coulombe, Y., Bohr, Vilhelm, Hendzel, M. J., Masson, J., Poirier, G. G. & Lebel, M., 4 Mar 2011, In: Journal of Proteome Research. 10, 3, p. 1216-27 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Improved glucose tolerance after intensive life style intervention occurs without changes in muscle ceramide or triacylglycerol in morbidly obese subjects
Helge, Jørn Wulff, Stallknecht, Bente Merete, Drachmann, T., Hellgren, L., Jiménez-Jiménez, R., Andersen, J. L., Richelsen, B. & Bruun, J. M., 1 Mar 2011, In: Acta Physiologica (Print). 201, 3, p. 357-64 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Evidence that OGG1 glycosylase protects neurons against oxidative DNA damage and cell death under ischemic conditions
Liu, D., Croteau, D. L., Souza-Pinto, N., Pitta, M., Tian, J., Wu, C., Jiang, H., Mustafa, K., Keijzers, G., Bohr, Vilhelm & Mattson, M. P., Feb 2011, In: Journal of Cerebral Blood Flow and Metabolism. 31, 2, p. 680-692 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Bi-directional routing of DNA mismatch repair protein human exonuclease 1 to replication foci and DNA double strand breaks
Liberti, S. E., Andersen, S. D., Wang, J., May, A., Miron, S., Perderiset, M., Keijzers, G., Nielsen, Finn Cilius, Charbonnier, J., Bohr, Vilhelm & Rasmussen, Lene Juel, 2 Jan 2011, In: DNA Repair. 10, 1, p. 73-86 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Factors that influence telomeric oxidative base damage and repair by DNA glycosylase OGG1
Rhee, D. B., Ghosh, A., Lu, J., Bohr, Vilhelm & Liu, Y., 2 Jan 2011, In: DNA Repair. 10, 1, p. 34-44 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Metabolism, genomics, and DNA repair in the mouse aging liver
Lebel, M., de Souza-Pinto, N. C. & Bohr, Vilhelm, 1 Jan 2011, In: Current Gerontology and Geriatrics Research. 2011, p. 859415Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Altered mitochondrial regulation in quadriceps muscles of patients with COPD
Naimi, A. I., Bourbeau, J., Perrault, H., Baril, J., Wright-Paradis, C., Rossi, A., Taivassalo, T., Sheel, A. W., Rabøl, R., Dela, Flemming & Boushel, R. C., 2011, In: Clinical Physiology and Functional Imaging. 31, 2, p. 124-31 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Association between plasma leptin and blood pressure in two population-based samples of children and adolescents
Grøntved, A., Steene-Johannessen, J., Kynde, I., Franks, P. W., Helge, Jørn Wulff, Froberg, K., Anderssen, S. A. & Andersen, L. B., 2011, In: Journal of Hypertension. 29, 6, p. 1093-100 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cerebral autoregulation dynamics in endurance-trained individuals
Lind-Holst, M., Cotter, J. D., Helge, Jørn Wulff, Boushel, R. C., Augustesen, H., Van Lieshout, J. J. & Pott, Frank Christian, 2011, In: Journal of Applied Physiology. 110, 5, p. 1327-33 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Endothelial function after 10 days of bed rest in individuals at risk for type 2 diabetes and cardiovascular disease
Sonne, M. P., Højbjerre, L., Alibegovic, A. C., Nielsen, L. B., Stallknecht, Bente Merete, Vaag, Allan & Dela, Flemming, 2011, In: Experimental Physiology. 96, p. 1000-9Research output: Contribution to journal › Journal article › Research › peer-review
- Published
High responders to resistance exercise training demonstrate differential regulation of skeletal muscle microRNA expression
Davidsen, P. K., Gallagher, I. J., Hartman, J. W., Tarnopolsky, M. A., Dela, Flemming, Helge, Jørn Wulff, Timmons, J. A. & Phillips, S. M., 2011, In: Journal of Applied Physiology. 110, 2, p. 309-17 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
High-fat feeding inhibits exercise-induced increase in mitochondrial respiratory flux in skeletal muscle
Skovbro, M., Boushel, R. C., Hansen, C. N., Helge, Jørn Wulff & Dela, Flemming, 2011, In: Journal of Applied Physiology. 110, 6, p. 1607-14 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Impact of physical inactivity on adipose tissue low-grade inflammation in first-degree relatives of type 2 diabetic patients
Højbjerre, L., Sonne, M. P., Alibegovic, A. C., Nielsen, N. B., Dela, Flemming, Vaag, Allan, Bruun, J. M. & Stallknecht, Bente Merete, 2011, In: Diabetes Care. 34, 10, p. 2265-72 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Increased lipolysis but diminished gene expression of lipases in subcutaneous adipose tissue of healthy young males with intrauterine growth retardation
Højbjerre, L., Alibegovic, A. C., Sonne, M. P., Dela, Flemming, Vaag, Allan, Bruun, J. M. & Stallknecht, Bente Merete, 2011, In: Journal of Applied Physiology. 111, 6, p. 1863-70 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Increased mitochondrial substrate sensitivity in skeletal muscle of patients with type 2 diabetes
Larsen, Steen, Stride, N., Hey-Mogensen, M., Hansen, C. N., Andersen, J. L., Madsbad, Sten, Worm, Dorte, Helge, Jørn Wulff & Dela, Flemming, 2011, In: Diabetologia. 54, 6, p. 1427-36 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Interleukin-6 release is higher across arm than leg muscles during whole-body exercise
Helge, Jørn Wulff, Klein, D. K., Andersen, T. M., van Hall, Gerrit, Calbet, J., Boushel, R. C. & Saltin, B., 2011, In: Experimental Physiology. 96, 6, p. 590-8 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Intracellular compartmentalization of skeletal muscle glycogen metabolism and insulin signalling
Prats Gavalda, Clara, Gomez-Cabello, A. & Vigelsø Hansen, A., 2011, In: Experimental Physiology. 96, 4, p. 385-390 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Muscle mitochondrial capacity exceeds maximal oxygen delivery in humans
Boushel, R. C., Gnaiger, E., Calbet, J. A. L., Gonzalez-Alonso, J., Wright-Paradis, C., Sondergaard, H., Ara, I., Helge, Jørn Wulff & Saltin, B., 2011, In: Mitochondrion. 11, 2, p. 303-7 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Normal mitochondrial function and increased fat oxidation capacity in leg and arm muscles in obese humans
Ara, I., Larsen, Steen, Stallknecht, Bente Merete, Guerra, B., Morales-Alamo, D., Andersen, J. L., Ponce-González, J. G., Guadalupe-Grau, A., Galbo, Henrik, Calbet, J. A. L. & Helge, Jørn Wulff, 2011, In: International Journal of Obesity. 35, 1, p. 99-108 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2010
- Published
Base excision repair activities differ in human lung cancer cells and corresponding normal controls
Karahalil, B., Bohr, Vilhelm & De Souza-Pinto, N. C., 1 Dec 2010, In: Anticancer Research. 30, 12, p. 4963-71 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Replication of an association of variation in the FOXO3A gene with human longevity using both case-control and longitudinal data
Soerensen, M., Dato, S., Christensen, K., McGue, M., Stevnsner, T. V., Bohr, Vilhelm & Christiansen, L., 1 Dec 2010, In: Aging Cell. 9, 6, p. 1010-7 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
DNA Repair and the Accumulation of Oxidatively Damaged DNA Are Affected by Fruit Intake in Mice
Croteau, D. L., de Souza-Pinto, N. C., Harboe, C., Keijzers, G., Zhang, Y., Becker, K., Sheng, S. & Bohr, Vilhelm, Dec 2010, In: Journals of Gerontology. Series A: Biological Sciences & Medical Sciences. 65, 12, p. 1300-1311 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Human RecQL4 helicase plays critical roles in prostate carcinogenesis
Su, Y., Meador, J. A., Calaf, G. M., Proietti De-Santis, L., Zhao, Y., Bohr, Vilhelm & Balajee, A. S., 15 Nov 2010, In: Cancer Research. 70, 22, p. 9207-17 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Insulin resistance induced by physical inactivity is associated with multiple transcriptional changes in skeletal muscle in young men
Alibegovic, A. C., Sonne, M. P., Højbjerre, L., Bork-Jensen, J., Jacobsen, S., Nilsson, E., Faerch, K., Hiscock, N., Mortensen, B., Friedrichsen, M., Stallknecht, Bente Merete, Dela, Flemming & Vaag, Allan, 1 Nov 2010, In: American Journal of Physiology: Endocrinology and Metabolism. 299, 5, p. E752-63 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Impact of physical inactivity on subcutaneous adipose tissue metabolism in healthy young male offspring of patients with type 2 diabetes
Højbjerre, L., Sonne, M., Alibegovic, A., Dela, Flemming, Vaag, A., Bruun, J. M., Christensen, Karl Bang & Stallknecht, Bente Merete, Nov 2010, In: Diabetes. 59, 11, p. 2790-2798 90 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The mitochondrial transcription factor A functions in mitochondrial base excision repair
Canugovi, C., Maynard, S., Bayne, A. V., Sykora, P., Tian, J., de Souza-Pinto, N. C., Croteau, D. L. & Bohr, Vilhelm, 5 Oct 2010, In: DNA Repair. 9, 10, p. 1080-9 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Telomerer--begyndelsen og enden
Bohr, Vilhelm, 4 Oct 2010, In: Ugeskrift for Laeger. 172, 40, p. 2744Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Intake of total dietary sugar and fibre is associated with insulin resistance among Danish 8–10- and 14–16-year-old girls but not boys. European Youth Heart Studies I and II
Kynde, I., Johnsen, N. F., Wedderkopp, N., Bygbjerg, Ib Christian, Helge, Jørn Wulff & Heitmann, Berit, 1 Oct 2010, In: Public Health Nutrition. 13, 10, p. 1669-74 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effect of physical training on mitochondrial respiration and reactive oxygen species release in skeletal muscle in patients with obesity and type 2 diabetes
Hey-Mogensen, M., Højlund, K., Vind, B. F., Wang, L., Dela, Flemming, Beck-Nielsen, H., Fernström, M. & Sahlin, K., 1 Sep 2010, In: Diabetologia. 53, 9, p. 1976-85 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mitochondrial base excision repair in mouse synaptosomes during normal aging and in a model of Alzheimer's disease
Diaz, R. G., Weissman, L., Yang, J., Bohr, Vilhelm & Stevnsner, T. V., 12 Aug 2010, In: Neurobiology of Aging.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Arm and leg substrate utilization and muscle adaptation after prolonged low-intensity training
Helge, Jørn Wulff, 1 Aug 2010, In: Acta Physiologica (Print). 199, 4, p. 519-28 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Functional capacity of XRCC1 protein variants identified in DNA repair-deficient Chinese hamster ovary cell lines and the human population
Berquist, B. R., Singh, D. K., Fan, J., Kim, D., Gillenwater, E., Kulkarni, A., Bohr, Vilhelm, Ackerman, E. J., Tomkinson, A. E. & Wilson, D. M., 1 Aug 2010, In: Nucleic Acids Symposium Series. 38, 15, p. 5023-35 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mitochondrial DNA repair and association with aging--an update
Diaz, R. G., Bohr, Vilhelm & Stevnsner, T. V., 1 Aug 2010, In: Experimental Gerontology. 45, 7-8, p. 478-88 11 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Mitochondrial base excision repair assays
Maynard, S., de Souza-Pinto, N. C., Scheibye-Knudsen, M. & Bohr, Vilhelm, 1 Aug 2010, In: Methods. 51, 4, p. 416-25 10 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Cockayne syndrome group B protein promotes mitochondrial DNA stability by supporting the DNA repair association with the mitochondrial membrane
Aamann, M. D., Sorensen, M. M., Hvitby, C. P., Berquist, B. R., Muftuoglu, M., Tian, J., de Souza-Pinto, N. C., Scheibye-Knudsen, M., Wilson, D. M., Stevnsner, T. V. & Bohr, Vilhelm, 1 Jul 2010, In: The FASEB Journal. 24, 7, p. 2334-46 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Conserved helicase domain of human RecQ4 is required for strand annealing-independent DNA unwinding
Rossi, M. L., Ghosh, A. K., Kulikowicz, T., Croteau, D. L. & Bohr, Vilhelm, 1 Jul 2010, In: DNA Repair. 9, 7, p. 796-804 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effect of physical training on insulin secretion and action in skeletal muscle and adipose tissue of first-degree relatives of type 2 diabetic patients
Dela, Flemming & Stallknecht, Bente Merete, 1 Jul 2010, In: American Journal of Physiology: Endocrinology and Metabolism. 299, 1, p. E80-91 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mitochondria and aging
Prolla, T. A., Bohr, Vilhelm & de Souza-Pinto, N. C., Jul 2010, In: Mechanisms of Ageing and Development. 131, 7-8, p. 449-50 2 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Substrate specific stimulation of NEIL1 by WRN but not the other human RecQ helicases
Popuri, V., Croteau, D. L. & Bohr, Vilhelm, 4 Jun 2010, In: DNA Repair. 9, 6, p. 636-42 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The involvement of human RECQL4 in DNA double-strand break repair
Singh, D. K., Karmakar, P., Aamann, M. D., Schurman, S. H., May, A., Croteau, D. L., Burks, L., Plon, S. E. & Bohr, Vilhelm, 1 Jun 2010, In: Aging Cell. 9, 3, p. 358-71 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cooperation of DNA-PKcs and WRN helicase in the maintenance of telomeric D-loops
Kusumoto-Matsuo, R., Opresko, P. L., Ramsden, D., Tahara, H. & Bohr, Vilhelm, 1 May 2010, In: Aging. 2, 5, p. 274-84 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Human RECQL5beta stimulates flap endonuclease 1
Speina, E., Dawut, L., Hedayati, M., Wang, Z., May, A., Schwendener, S., Janscak, P., Croteau, D. L. & Bohr, Vilhelm, 1 May 2010, In: Nucleic Acids Symposium Series. 38, 9, p. 2904-16 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Childhood hypo-adiponectinaemia but not hyper-leptinaemia is associated with insulin insensitivity 6 years later
Kynde, I., Heitmann, B. L., Bygbjerg, Ib Christian, Andersen, L. B. & Helge, Jørn Wulff, May 2010, In: Pediatric Diabetes. 11, 3, p. 195-202 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effect of 10 days of bedrest on metabolic and vascular insulin action: a study in individuals at risk for type 2 diabetes
Sonne, M. P., Alibegovic, A. C., Højbjerre, L., Vaag, Allan, Stallknecht, Bente Merete & Dela, Flemming, 1 Apr 2010, In: Journal of Applied Physiology. 108, 4, p. 830-7 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Nutrition and aging
Cheng, W., Bohr, Vilhelm & de Cabo, R., 1 Apr 2010, In: Mechanisms of Ageing and Development. 131, 4, p. 223-4 2 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Depletion of WRN protein causes RACK1 to activate several protein kinase C isoforms
Massip, L., Garand, C., Labbé, A., Perreault, E., Turaga, R. V. N., Bohr, Vilhelm & Lebel, M., 11 Mar 2010, In: Oncogene. 29, 10, p. 1486-97 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Roles of Werner syndrome protein in protection of genome integrity
Rossi, M. L., Ghosh, A. K. & Bohr, Vilhelm, 2 Mar 2010, In: DNA Repair. 9, 3, p. 331-44 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Impact papers on aging in 2009
Blagosklonny, M. V., Campisi, J., Sinclair, D. A., Bartke, A., Blasco, M. A., Bonner, W. M., Bohr, V. A., Brosh, R. M., Brunet, A., Depinho, R. A., Donehower, L. A., Finch, C. E., Finkel, T., Gorospe, M., Gudkov, A. V., Hall, M. N., Hekimi, S., Helfand, S. L., Karlseder, J., Kenyon, C. & 15 others, , 1 Mar 2010, In: Aging. 2, 3, p. 111-21 11 p.Research output: Contribution to journal › Review › Research
- Published
Time trends in physical activity in leisure time in the Danish population from 1987 to 2005
Petersen, C. B., Thygesen, L. C., Helge, Jørn Wulff, Grønbaek, M. & Tolstrup, J. S., 1 Mar 2010, In: Scandinavian Journal of Public Health. 38, 2, p. 121-8 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Regional anatomic differences in skeletal muscle mitochondrial respiration in type 2 diabetes and obesity
Rabøl, R., Larsen, Steen, Højberg, P. M. V., Almdal, Thomas Peter, Boushel, R. C., Haugaard, Steen Bendix, Andersen, J. L., Madsbad, Sten & Dela, Flemming, 1 Feb 2010, In: Journal of Clinical Endocrinology and Metabolism. 95, 2, p. 857-63 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Earl R. Stadtman
Levine, R. L. & Bohr, Vilhelm, 1 Jan 2010, In: Mechanisms of Ageing and Development. 131, 1, p. 1Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cardiac and metabolic changes in long-term high fructose-fat fed rats with severe obesity and extensive intramyocardial lipid accumulation
Axelsen, L. N., Lademann, J. B., Petersen, J. S., von Holstein-Rathlou, Niels-Henrik, Ploug, Thorkil, Prats Gavalda, Clara, Pedersen, H. D. & Kjølbye, A. L., 2010, In: American Journal of Physiology: Regulatory, Integrative and Comparative Physiology. 298, 6, p. R1560-70Research output: Contribution to journal › Journal article › Research › peer-review
- Published
FAT/CD36 is localized in sarcolemma and in vesicle-like structures in subsarcolemma regions but not in mitochondria
Jeppesen, J., Mogensen, M., Prats Gavalda, Clara, Sahlin, K., Madsen, K. & Kiens, Bente, 2010, In: Journal of Lipid Research. 51, 6, p. 1504-1512 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Fat oxidation at rest predicts peak fat oxidation during exercise and metabolic phenotype in overweight men
Rosenkilde, M., Nordby, P., Nielsen, L. B., Stallknecht, Bente Merete & Helge, Jørn Wulff, 2010, In: International Journal of Obesity. 34, 5, p. 871-7 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Increased rate of whole body lipolysis before and after 9 days of bed rest in healthy young men born with low birth weight
Alibegovic, A. C., Hojbjerre, L., Sonne, M., van Hall, Gerrit, Alsted, T. J., Kiens, Bente, Stallknecht, Bente Merete, Dela, Flemming & Vaag, Allan, 2010, In: American Journal of Physiology: Endocrinology and Metabolism. 298, 3, p. E555-E564 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Intake of total dietary sugar and fibre is associated with insulin resistance among Danish 8-10- and 14-16-year-old girls but not boys. European Youth Heart Studies I and II
Kynde, I., Johnsen, N. F., Wedderkopp, N., Bygbjerg, Ib Christian, Helge, Jørn Wulff & Heitmann, Berit, 2010, In: Public Health Nutrition. 13, 10, p. 1669-74Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Kost, motion og sport
Helge, Jørn Wulff, McDonald, C. & Kjær, Michael, 2010, Menneskets Ernæring. 3 ed. København: Munksgaard , p. 401-424 24 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Communication
- Published
Leptin receptor 170 kDa (OB-R170) protein expression is reduced in obese human skeletal muscle: a potential mechanism of leptin resistance
Fuentes, T., Ara, I., Guadalupe-Grau, A., Larsen, S., Stallknecht, Bente Merete, Olmedillas, H., Santana, A., Helge, Jørn Wulff, Calbet, J. A. L. & Guerra, B., 2010, In: Experimental Physiology. 95, 1, p. 160-71 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mitochondrial helicases and mitochondrial genome maintenance
de Souza-Pinto, N. C., Aamann, M. D., Kulikowicz, T., Stevnsner, T. V. & Bohr, Vilhelm, 2010, In: Mechanisms of Ageing and Development. 131, 7-8, p. 503-10 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mitochondrial respiration in subcutaneous and visceral adipose tissue from patients with morbid obesity
Kraunsøe, R., Boushel, R. C., Hansen, C. N., Schjerling, Peter, Qvortrup, Klaus, Støckel, M., Mikines, K. J. & Dela, Flemming, 2010, In: Journal of Physiology. 588, 12, p. 2023-2032 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Muscle ceramide content in man is higher in type I than type II fibers and not influenced by glycogen content
Nordby, P., Prats Gavalda, Clara, Kristensen, D., Ekroos, K., Forsberg, G., Andersen, J. L., Ploug, Thorkil, Dela, Flemming, Storlien, L. & Helge, Jørn Wulff, 2010, In: Journal of Applied Physiology. 109, 5, p. 935-943 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Neurons efficiently repair glutamate-induced oxidative DNA damage by a process involving CREB-mediated up-regulation of apurinic endonuclease 1
Yang, J., Tadokoro, T., Keijzers, G., Mattson, M. P. & Bohr, Vilhelm, 2010, In: Journal of Biological Chemistry. 285, 36, p. 28191-9 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2009
- Published
The recombination protein RAD52 cooperates with the excision repair protein OGG1 for the repair of oxidative lesions in mammalian cells
de Souza-Pinto, N. C., Maynard, S., Hashiguchi, K., Hu, J., Muftuoglu, M. & Bohr, Vilhelm, Aug 2009, In: Molecular and Cellular Biology. 29, 16, p. 4441-54 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Sex hormone-binding globulin levels predict insulin sensitivity, disposition index, and cardiovascular risk during puberty
Sørensen, K., Aksglaede, L., Munch-Andersen, T., Aachmann-Andersen, N. J., Petersen, Jørgen Holm, Hilsted, Linda, Helge, Jørn Wulff & Juul, Anders, 1 May 2009, In: Diabetes Care. 32, 5, p. 909-14 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cockayne syndrome group B protein stimulates repair of formamidopyrimidines by NEIL1 DNA glycosylase
Muftuoglu, M., de Souza-Pinto, N. C., Dogan, A., Aamann, M., Stevnsner, T., Rybanska, I., Kirkali, G., Dizdaroglu, M. & Bohr, Vilhelm, Apr 2009, In: Journal of Biological Chemistry. 284, 14, p. 9270-9 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Base excision repair of oxidative DNA damage and association with cancer and aging
Maynard, S., Schurman, S. H., Harboe, C., de Souza-Pinto, N. C. & Bohr, Vilhelm, 1 Jan 2009, In: Carcinogenesis. 30, 1, p. 2-10 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
SIRT6 stabilizes DNA-dependent protein kinase at chromatin for DNA double-strand break repair
McCord, R. A., Michishita, E., Hong, T., Berber, E., Boxer, L. D., Kusumoto, R., Guan, S., Shi, X., Gozani, O., Burlingame, A. L., Bohr, Vilhelm & Chua, K. F., 1 Jan 2009, In: Aging. 1, 1, p. 109-21 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Are substrate use during exercise and mitochondrial respiratory capacity decreased in arm and leg muscle in type 2 diabetes?
Larsen, Steen, Ara, I., Rabøl, R., Andersen, J. L., Boushel, R., Dela, Flemming & Helge, Jørn Wulff, 2009, In: Diabetologia. 52, 7, p. 1400-8 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cardiovascular disease markers in type 2 diabetes: the effects of a moderate home-based exercise training programme
Scheede-Bergdahl, C., Benee Olsen, D., Reving, D., Boushel, R. & Dela, Flemming, 2009, In: Diabetes and Vascular Disease Research. 6, 4, p. 291-6 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Diminished insulin-mediated forearm blood flow and muscle glucose uptake in young men with low birth weight
Sonne, M. P., Højbjerre, L., Alibegovic, A. C., Vaag, Allan, Stallknecht, Bente Merete & Dela, Flemming, 2009, In: Journal of Vascular Research. 47, 2, p. 139-47 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Dual regulation of muscle glycogen synthase during exercise by activation and compartmentalization
Prats Gavalda, Clara, Helge, Jørn Wulff, Nordby, P., Qvortrup, Klaus, Ploug, Thorkil, Dela, Flemming & Wojtaszewski, Jørgen F P, 2009, In: Journal of Biological Chemistry. 284, 23, p. 15692-15700 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effect of Hyperglycemia on Mitochondrial Respiration in Type 2 Diabetes
Rabøl, R., Højberg, P. M. V., Almdal, Thomas Peter, Boushel, R., Haugaard, S. B., Madsbad, Sten, Dela, Flemming, Rabøl, R., Højberg, P. M. V., Almdal, T., Boushel, R., Haugaard, S. B., Madsbad, Sten & Dela, F., 2009, In: Journal of Clinical Endocrinology and Metabolism. 94, 4, p. 1372-78Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effects of a 14-month low-cost maintenance training program in patients with chronic systolic heart failure: a randomized study
Prescott, Eva, Hjardem-Hansen, R., Dela, Flemming, Orkild, B., Teisner, A. & Nielsen, H., 2009, In: European Journal of Cardiovascular Prevention & Rehabilitation. 16, 4, p. 430-7 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Exercise training in older patients with systolic heart failure: Adherence, exercise capacity, inflammation and glycemic control
Prescott, Eva, Hjardem-Hansen, R., Dela, Flemming, Teisner, A. & Nielsen, H., 2009, In: Scandinavian Cardiovascular Journal. 43, p. 249-255 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Fysisk traening ved type 2-diabetes. Er tre gange ti minutter om dagen bedre end 30 minutter?--sekundaerpublikation
Dahl-Petersen, I., Eriksen, L., Haugaard, S. B. & Dela, Flemming, 2009, In: Ugeskrift for læger. 171, 11, p. 878-80 2 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Hypoadiponectinemia in overweight children contributes to a negative metabolic risk profile 6 years later
Kynde, I., Heitmann, B. L., Bygbjerg, Ib Christian, Andersen, L. B. & Helge, Jørn Wulff, 2009, In: Metabolism - Clinical and Experimental. 58, 12, p. 1817-24 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Impact of 9 days of bed rest on hepatic and peripheral insulin action, insulin secretion, and whole-body lipolysis in healthy young male offspring of patients with type 2 diabetes
Alibegovic, A. C., Højbjerre, L., Sonne, M. P., van Hall, G., Stallknecht, Bente Merete, Dela, Flemming & Vaag, Allan, 2009, In: Diabetes. 58, 12, p. 2749-56 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Impact of the growth hormone receptor exon 3 deletion gene polymorphism on glucose metabolism, lipids, and insulin-like growth factor-I levels during puberty
Sørensen, K., Aksglaede, L., Munch-Andersen, T., Aachmann-Andersen, N. J., Leffers, H., Helge, Jørn Wulff, Hilsted, Linda & Juul, Anders, 2009, In: Journal of Clinical Endocrinology and Metabolism. 94, 8, p. 2966-9 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Impaired endothelial function and insulin action in first-degree relatives of patients with type 2 diabetes mellitus
Sonne, M. P., Højbjerre, L., Alibegovic, A. A., Vaag, Allan, Stallknecht, Bente Merete & Dela, Flemming, 2009, In: Metabolism - Clinical and Experimental. 58, 1, p. 93-101 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Improved glycaemic control decreases inner mitochondrial membrane leak in type 2 diabetes
Rabøl, R., Højberg, P. M. V., Almdal, Thomas Peter, Boushel, R., Haugaard, S. B., Madsbad, Sten, Dela, Flemming, Rabøl, R., Højberg, P. M. V., Almdal, T., Boushel, R., Haugaard, S. B., Madsbad, Sten & Dela, F., 2009, In: Diabetic Medicine. 11, 4, p. 355-60 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Insulin and non-insulin mediated vasodilation and glucose uptake in patients with type 2 diabetes
Scheede-Bergdahl, C., Olsen, D. B., Reving, D., Boushel, R. & Dela, Flemming, 2009, In: Diabetes Research and Clinical Practice. 85, 3, p. 243-51 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The relationship between skeletal muscle mitochondrial citrate synthase activity and whole body oxygen uptake adaptations in response to exercise training.
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Meal induced gut hormone secretion is altered in aerobically trained compared to sedentary young healthy males
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Two weeks of metformin treatment enhances mitochondrial respiration in skeletal muscle of AMPK kinase dead but not wild type mice
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