Individualized Health

  1. 2013
  2. Published

    Rac1 signaling is required for insulin-stimulated glucose uptake and is dysregulated in insulin-resistant murine and human skeletal muscle

    Sylow, Lykke, Jensen, Thomas Elbenhardt, Kleinert, Maximilian, Højlund, K., Kiens, Bente, Wojtaszewski, Jørgen F P, Prats Gavalda, Clara, Schjerling, P. & Richter, Erik A., 2013, In: Diabetes. 62, 6, p. 1865-1875 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Subcellular localization and mechanism of secretion of vascular endothelial growth factor in human skeletal muscle

    Høier, B., Prats Gavalda, Clara, Qvortrup, Klaus, Pilegaard, Henriette, Bangsbo, Jens & Hellsten, Ylva, 2013, In: F A S E B Journal. 27, 9, p. 3496-3504 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published
  5. 2012
  6. Published

    The helicase and ATPase activities of RECQL4 are compromised by mutations reported in three human patients

    Jensen, M. B., Dunn, C. A., Keijzers, G., Kulikowicz, T., Rasmussen, Lene Juel, Croteau, D. L. & Bohr, Vilhelm, Nov 2012, In: Aging. 4, 11, p. 790-802 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Høj puls og masser af fedt

    Christensen, Dirk Lund & Helge, Jørn Wulff, 15 Jun 2012, In: Weekendavisen. 24, p. 11 1 p.

    Research output: Contribution to journalContribution to newspaper - Newspaper articleCommunication

  8. Published

    Cockayne syndrome group B protein prevents the accumulation of damaged mitochondria by promoting mitochondrial autophagy

    Scheibye-Knudsen, M., Ramamoorthy, M., Sykora, P., Maynard, S., Lin, P., Minor, R. K., Wilson, D. M., Cooper, M., Spencer, R., de Cabo, R., Croteau, D. L. & Bohr, Vilhelm, Apr 2012, In: The Journal of Experimental Medicine. 209, 4, p. 855-69 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    14-3-3 checkpoint regulatory proteins interact specifically with DNA repair protein human exonuclease 1 (hEXO1) via a semi-conserved motif

    Andersen, S. D., Keijzers, G., Rampakakis, E., Engels, K., Luhn, P., El-Shemerly, M., Nielsen, Finn Cilius, Du, Y., May, A., Bohr, Vilhelm, Ferrari, S., Zannis-Hadjopoulos, M., Fu, H. & Rasmussen, Lene Juel, Mar 2012, In: D N A Repair. 11, 3, p. 267-77 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Metabolic profile in two physically active Inuit groups consuming either a western or a traditional Inuit diet

    Munch-Andersen, T., Olsen, D. B., Søndergaard, H., Daugaard, J. R., Bysted, A., Christensen, Dirk Lund, Saltin, B. & Helge, Jørn Wulff, Mar 2012, In: International Journal of Circumpolar Health. 71, 8 p., 17342.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    5'-AMP activated protein kinase is involved in the regulation of myocardial ß-oxidative capacity in mice

    Stride, N., Larsen, S., Treebak, Jonas Thue, Hansen, C. N., Hey-Mogensen, M., Speerschneider, T., Jensen, Thomas Elbenhardt, Jeppesen, J., Wojtaszewski, Jørgen F P, Richter, Erik A., Køber, Lars Valeur & Dela, Flemming, 22 Feb 2012, In: Frontiers in Physiology. 3, 7 p., 00033.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Endurance training per se increases metabolic health in young, moderately overweight men

    Nordby, P., Auerbach, P. L., Rosenkilde, M., Kristiansen, L., Thomasen, J. R., Rygaard, L., Groth, R., Brandt, N., Helge, Jørn Wulff, Richter, Erik A., Ploug, Thorkil & Stallknecht, Bente Merete, 2012, In: Obesity. 20, 11, p. 2202-2212 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Muscle ceramide content is similar after 3 weeks' consumption of fat or carbohydrate diet in a crossover design in patients with type 2 diabetes

    Helge, Jørn Wulff, Tobin, L., Drachmann, T., Hellgren, L., Dela, Flemming & Galbo, Henrik, 2012, In: European Journal of Applied Physiology. 112, 3, p. 911-918

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Muscle inflammatory signaling in response to 9 days of physical inactivity in young men with low compared to normal birth weight

    Friedrichsen, M., Ribel-Madsen, R., Mortensen, B., Hansen, C. N., Alibegovic, A. C., Højbjerre, L., Sonne, M. P., Wojtaszewski, Jørgen F P, Stallknecht, Bente Merete, Dela, Flemming & Vaag, Allan, 2012, In: European Journal of Endocrinology. 167, 6, p. 829-838 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    RECQL4 localizes to mitochondria and preserves mitochondrial DNA integrity

    Croteau, D. L., Rossi, M. L., Canugovi, C., Tian, J., Sykora, P., Ramamoorthy, M., Wang, Z. M., Singh, D. K., Akbari, M., Kasiviswanathan, R., Copeland, W. C. & Bohr, Vilhelm, 2012, In: Aging Cell. 11, 3, p. 456-66 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Skeletal muscle mitochondrial respiration in AMPKa2 kinase dead mice

    Larsen, S., Kristensen, Jonas Møller, Stride, N., Wojtaszewski, Jørgen F P, Helge, Jørn Wulff & Dela, Flemming, 2012, In: Acta Physiologica (Print). 205, 2, p. 314-320 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. 2011
  18. Published

    Aging, longevity and health

    Rasmussen, Lene Juel, Sander, M., Wewer, Ulla M. & Bohr, Vilhelm, 23 Jul 2011, In: Mechanisms of Ageing and Development. p. 522-32 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Negative Regulation of STAT3 Protein-mediated Cellular Respiration by SIRT1 Protein

    Bernier, M., Paul, R. K., Martin-Montalvo, A., Scheibye-Knudsen, M., Song, S., He, H., Armour, S. M., Hubbard, B. P., Bohr, Vilhelm, Wang, L., Zong, Y., Sinclair, D. A. & de Cabo, R., 3 Jun 2011, In: The Journal of Biological Chemistry. 286, 22, p. 19270-9 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Aprataxin localizes to mitochondria and preserves mitochondrial function

    Sykora, P., Croteau, D. L., Bohr, Vilhelm & Wilson, D. M., 3 May 2011, In: Proceedings of the National Academy of Sciences USA (PNAS). 108, 18, p. 7437-42 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    DNA repair deficiency in neurodegeneration

    Jeppesen, D. K., Bohr, Vilhelm & Stevnsner, T. V., 30 Apr 2011, In: Progress in Neurobiology. 94, 2, p. 166-200 35 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Non-B DNA-forming sequences and WRN deficiency independently increase the frequency of base substitution in human cells

    Bacolla, A., Wang, G., Jain, A., Chuzhanova, N. A., Cer, R. Z., Collins, J. R., Cooper, D. N., Bohr, Vilhelm & Vasquez, K. M., 25 Mar 2011, In: The Journal of Biological Chemistry. 286, 12, p. 10017-26 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Proteome-wide identification of WRN-interacting proteins in untreated and nuclease-treated samples

    Lachapelle, S., Gagné, J., Garand, C., Desbiens, M., Coulombe, Y., Bohr, Vilhelm, Hendzel, M. J., Masson, J., Poirier, G. G. & Lebel, M., 4 Mar 2011, In: Journal of Proteome Research. 10, 3, p. 1216-27 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Improved glucose tolerance after intensive life style intervention occurs without changes in muscle ceramide or triacylglycerol in morbidly obese subjects

    Helge, Jørn Wulff, Stallknecht, Bente Merete, Drachmann, T., Hellgren, L., Jiménez-Jiménez, R., Andersen, J. L., Richelsen, B. & Bruun, J. M., 1 Mar 2011, In: Acta Physiologica (Print). 201, 3, p. 357-64 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Evidence that OGG1 glycosylase protects neurons against oxidative DNA damage and cell death under ischemic conditions

    Liu, D., Croteau, D. L., Souza-Pinto, N., Pitta, M., Tian, J., Wu, C., Jiang, H., Mustafa, K., Keijzers, G., Bohr, Vilhelm & Mattson, M. P., Feb 2011, In: Journal of Cerebral Blood Flow and Metabolism. 31, 2, p. 680-692 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Bi-directional routing of DNA mismatch repair protein human exonuclease 1 to replication foci and DNA double strand breaks

    Liberti, S. E., Andersen, S. D., Wang, J., May, A., Miron, S., Perderiset, M., Keijzers, G., Nielsen, Finn Cilius, Charbonnier, J., Bohr, Vilhelm & Rasmussen, Lene Juel, 2 Jan 2011, In: DNA Repair. 10, 1, p. 73-86 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Factors that influence telomeric oxidative base damage and repair by DNA glycosylase OGG1

    Rhee, D. B., Ghosh, A., Lu, J., Bohr, Vilhelm & Liu, Y., 2 Jan 2011, In: DNA Repair. 10, 1, p. 34-44 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Metabolism, genomics, and DNA repair in the mouse aging liver

    Lebel, M., de Souza-Pinto, N. C. & Bohr, Vilhelm, 1 Jan 2011, In: Current Gerontology and Geriatrics Research. 2011, p. 859415

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Altered mitochondrial regulation in quadriceps muscles of patients with COPD

    Naimi, A. I., Bourbeau, J., Perrault, H., Baril, J., Wright-Paradis, C., Rossi, A., Taivassalo, T., Sheel, A. W., Rabøl, R., Dela, Flemming & Boushel, R. C., 2011, In: Clinical Physiology and Functional Imaging. 31, 2, p. 124-31 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Association between plasma leptin and blood pressure in two population-based samples of children and adolescents

    Grøntved, A., Steene-Johannessen, J., Kynde, I., Franks, P. W., Helge, Jørn Wulff, Froberg, K., Anderssen, S. A. & Andersen, L. B., 2011, In: Journal of Hypertension. 29, 6, p. 1093-100 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    Cerebral autoregulation dynamics in endurance-trained individuals

    Lind-Holst, M., Cotter, J. D., Helge, Jørn Wulff, Boushel, R. C., Augustesen, H., Van Lieshout, J. J. & Pott, Frank Christian, 2011, In: Journal of Applied Physiology. 110, 5, p. 1327-33 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    Endothelial function after 10 days of bed rest in individuals at risk for type 2 diabetes and cardiovascular disease

    Sonne, M. P., Højbjerre, L., Alibegovic, A. C., Nielsen, L. B., Stallknecht, Bente Merete, Vaag, Allan & Dela, Flemming, 2011, In: Experimental Physiology. 96, p. 1000-9

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    High responders to resistance exercise training demonstrate differential regulation of skeletal muscle microRNA expression

    Davidsen, P. K., Gallagher, I. J., Hartman, J. W., Tarnopolsky, M. A., Dela, Flemming, Helge, Jørn Wulff, Timmons, J. A. & Phillips, S. M., 2011, In: Journal of Applied Physiology. 110, 2, p. 309-17 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    High-fat feeding inhibits exercise-induced increase in mitochondrial respiratory flux in skeletal muscle

    Skovbro, M., Boushel, R. C., Hansen, C. N., Helge, Jørn Wulff & Dela, Flemming, 2011, In: Journal of Applied Physiology. 110, 6, p. 1607-14 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    Impact of physical inactivity on adipose tissue low-grade inflammation in first-degree relatives of type 2 diabetic patients

    Højbjerre, L., Sonne, M. P., Alibegovic, A. C., Nielsen, N. B., Dela, Flemming, Vaag, Allan, Bruun, J. M. & Stallknecht, Bente Merete, 2011, In: Diabetes Care. 34, 10, p. 2265-72 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    Increased lipolysis but diminished gene expression of lipases in subcutaneous adipose tissue of healthy young males with intrauterine growth retardation

    Højbjerre, L., Alibegovic, A. C., Sonne, M. P., Dela, Flemming, Vaag, Allan, Bruun, J. M. & Stallknecht, Bente Merete, 2011, In: Journal of Applied Physiology. 111, 6, p. 1863-70 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    Increased mitochondrial substrate sensitivity in skeletal muscle of patients with type 2 diabetes

    Larsen, Steen, Stride, N., Hey-Mogensen, M., Hansen, C. N., Andersen, J. L., Madsbad, Sten, Worm, Dorte, Helge, Jørn Wulff & Dela, Flemming, 2011, In: Diabetologia. 54, 6, p. 1427-36 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    Interleukin-6 release is higher across arm than leg muscles during whole-body exercise

    Helge, Jørn Wulff, Klein, D. K., Andersen, T. M., van Hall, Gerrit, Calbet, J., Boushel, R. C. & Saltin, B., 2011, In: Experimental Physiology. 96, 6, p. 590-8 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Intracellular compartmentalization of skeletal muscle glycogen metabolism and insulin signalling

    Prats Gavalda, Clara, Gomez-Cabello, A. & Vigelsø Hansen, A., 2011, In: Experimental Physiology. 96, 4, p. 385-390 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    Muscle mitochondrial capacity exceeds maximal oxygen delivery in humans

    Boushel, R. C., Gnaiger, E., Calbet, J. A. L., Gonzalez-Alonso, J., Wright-Paradis, C., Sondergaard, H., Ara, I., Helge, Jørn Wulff & Saltin, B., 2011, In: Mitochondrion. 11, 2, p. 303-7 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    Normal mitochondrial function and increased fat oxidation capacity in leg and arm muscles in obese humans

    Ara, I., Larsen, Steen, Stallknecht, Bente Merete, Guerra, B., Morales-Alamo, D., Andersen, J. L., Ponce-González, J. G., Guadalupe-Grau, A., Galbo, Henrik, Calbet, J. A. L. & Helge, Jørn Wulff, 2011, In: International Journal of Obesity. 35, 1, p. 99-108 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. 2010
  43. Published

    Base excision repair activities differ in human lung cancer cells and corresponding normal controls

    Karahalil, B., Bohr, Vilhelm & De Souza-Pinto, N. C., 1 Dec 2010, In: Anticancer Research. 30, 12, p. 4963-71 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    Replication of an association of variation in the FOXO3A gene with human longevity using both case-control and longitudinal data

    Soerensen, M., Dato, S., Christensen, K., McGue, M., Stevnsner, T. V., Bohr, Vilhelm & Christiansen, L., 1 Dec 2010, In: Aging Cell. 9, 6, p. 1010-7 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    DNA Repair and the Accumulation of Oxidatively Damaged DNA Are Affected by Fruit Intake in Mice

    Croteau, D. L., de Souza-Pinto, N. C., Harboe, C., Keijzers, G., Zhang, Y., Becker, K., Sheng, S. & Bohr, Vilhelm, Dec 2010, In: Journals of Gerontology. Series A: Biological Sciences & Medical Sciences. 65, 12, p. 1300-1311 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    Human RecQL4 helicase plays critical roles in prostate carcinogenesis

    Su, Y., Meador, J. A., Calaf, G. M., Proietti De-Santis, L., Zhao, Y., Bohr, Vilhelm & Balajee, A. S., 15 Nov 2010, In: Cancer Research. 70, 22, p. 9207-17 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    Insulin resistance induced by physical inactivity is associated with multiple transcriptional changes in skeletal muscle in young men

    Alibegovic, A. C., Sonne, M. P., Højbjerre, L., Bork-Jensen, J., Jacobsen, S., Nilsson, E., Faerch, K., Hiscock, N., Mortensen, B., Friedrichsen, M., Stallknecht, Bente Merete, Dela, Flemming & Vaag, Allan, 1 Nov 2010, In: American Journal of Physiology: Endocrinology and Metabolism. 299, 5, p. E752-63 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    Impact of physical inactivity on subcutaneous adipose tissue metabolism in healthy young male offspring of patients with type 2 diabetes

    Højbjerre, L., Sonne, M., Alibegovic, A., Dela, Flemming, Vaag, A., Bruun, J. M., Christensen, Karl Bang & Stallknecht, Bente Merete, Nov 2010, In: Diabetes. 59, 11, p. 2790-2798 90 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    The mitochondrial transcription factor A functions in mitochondrial base excision repair

    Canugovi, C., Maynard, S., Bayne, A. V., Sykora, P., Tian, J., de Souza-Pinto, N. C., Croteau, D. L. & Bohr, Vilhelm, 5 Oct 2010, In: DNA Repair. 9, 10, p. 1080-9 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    Telomerer--begyndelsen og enden

    Bohr, Vilhelm, 4 Oct 2010, In: Ugeskrift for Laeger. 172, 40, p. 2744

    Research output: Contribution to journalJournal articleResearchpeer-review

  51. Published

    Intake of total dietary sugar and fibre is associated with insulin resistance among Danish 8–10- and 14–16-year-old girls but not boys. European Youth Heart Studies I and II

    Kynde, I., Johnsen, N. F., Wedderkopp, N., Bygbjerg, Ib Christian, Helge, Jørn Wulff & Heitmann, Berit, 1 Oct 2010, In: Public Health Nutrition. 13, 10, p. 1669-74 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  52. Published

    Effect of physical training on mitochondrial respiration and reactive oxygen species release in skeletal muscle in patients with obesity and type 2 diabetes

    Hey-Mogensen, M., Højlund, K., Vind, B. F., Wang, L., Dela, Flemming, Beck-Nielsen, H., Fernström, M. & Sahlin, K., 1 Sep 2010, In: Diabetologia. 53, 9, p. 1976-85 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  53. Published

    Mitochondrial base excision repair in mouse synaptosomes during normal aging and in a model of Alzheimer's disease

    Diaz, R. G., Weissman, L., Yang, J., Bohr, Vilhelm & Stevnsner, T. V., 12 Aug 2010, In: Neurobiology of Aging.

    Research output: Contribution to journalJournal articleResearchpeer-review

  54. Published

    Arm and leg substrate utilization and muscle adaptation after prolonged low-intensity training

    Helge, Jørn Wulff, 1 Aug 2010, In: Acta Physiologica (Print). 199, 4, p. 519-28 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  55. Published

    Functional capacity of XRCC1 protein variants identified in DNA repair-deficient Chinese hamster ovary cell lines and the human population

    Berquist, B. R., Singh, D. K., Fan, J., Kim, D., Gillenwater, E., Kulkarni, A., Bohr, Vilhelm, Ackerman, E. J., Tomkinson, A. E. & Wilson, D. M., 1 Aug 2010, In: Nucleic Acids Symposium Series. 38, 15, p. 5023-35 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  56. Published

    Mitochondrial DNA repair and association with aging--an update

    Diaz, R. G., Bohr, Vilhelm & Stevnsner, T. V., 1 Aug 2010, In: Experimental Gerontology. 45, 7-8, p. 478-88 11 p.

    Research output: Contribution to journalReviewResearchpeer-review

  57. Published

    Mitochondrial base excision repair assays

    Maynard, S., de Souza-Pinto, N. C., Scheibye-Knudsen, M. & Bohr, Vilhelm, 1 Aug 2010, In: Methods. 51, 4, p. 416-25 10 p.

    Research output: Contribution to journalReviewResearchpeer-review

  58. Published

    Cockayne syndrome group B protein promotes mitochondrial DNA stability by supporting the DNA repair association with the mitochondrial membrane

    Aamann, M. D., Sorensen, M. M., Hvitby, C. P., Berquist, B. R., Muftuoglu, M., Tian, J., de Souza-Pinto, N. C., Scheibye-Knudsen, M., Wilson, D. M., Stevnsner, T. V. & Bohr, Vilhelm, 1 Jul 2010, In: The FASEB Journal. 24, 7, p. 2334-46 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  59. Published

    Conserved helicase domain of human RecQ4 is required for strand annealing-independent DNA unwinding

    Rossi, M. L., Ghosh, A. K., Kulikowicz, T., Croteau, D. L. & Bohr, Vilhelm, 1 Jul 2010, In: DNA Repair. 9, 7, p. 796-804 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  60. Published

    Effect of physical training on insulin secretion and action in skeletal muscle and adipose tissue of first-degree relatives of type 2 diabetic patients

    Dela, Flemming & Stallknecht, Bente Merete, 1 Jul 2010, In: American Journal of Physiology: Endocrinology and Metabolism. 299, 1, p. E80-91 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  61. Published

    Mitochondria and aging

    Prolla, T. A., Bohr, Vilhelm & de Souza-Pinto, N. C., Jul 2010, In: Mechanisms of Ageing and Development. 131, 7-8, p. 449-50 2 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  62. Published

    Substrate specific stimulation of NEIL1 by WRN but not the other human RecQ helicases

    Popuri, V., Croteau, D. L. & Bohr, Vilhelm, 4 Jun 2010, In: DNA Repair. 9, 6, p. 636-42 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  63. Published

    The involvement of human RECQL4 in DNA double-strand break repair

    Singh, D. K., Karmakar, P., Aamann, M. D., Schurman, S. H., May, A., Croteau, D. L., Burks, L., Plon, S. E. & Bohr, Vilhelm, 1 Jun 2010, In: Aging Cell. 9, 3, p. 358-71 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  64. Published

    Cooperation of DNA-PKcs and WRN helicase in the maintenance of telomeric D-loops

    Kusumoto-Matsuo, R., Opresko, P. L., Ramsden, D., Tahara, H. & Bohr, Vilhelm, 1 May 2010, In: Aging. 2, 5, p. 274-84 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  65. Published

    Human RECQL5beta stimulates flap endonuclease 1

    Speina, E., Dawut, L., Hedayati, M., Wang, Z., May, A., Schwendener, S., Janscak, P., Croteau, D. L. & Bohr, Vilhelm, 1 May 2010, In: Nucleic Acids Symposium Series. 38, 9, p. 2904-16 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  66. Published

    Childhood hypo-adiponectinaemia but not hyper-leptinaemia is associated with insulin insensitivity 6 years later

    Kynde, I., Heitmann, B. L., Bygbjerg, Ib Christian, Andersen, L. B. & Helge, Jørn Wulff, May 2010, In: Pediatric Diabetes. 11, 3, p. 195-202 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  67. Published

    Effect of 10 days of bedrest on metabolic and vascular insulin action: a study in individuals at risk for type 2 diabetes

    Sonne, M. P., Alibegovic, A. C., Højbjerre, L., Vaag, Allan, Stallknecht, Bente Merete & Dela, Flemming, 1 Apr 2010, In: Journal of Applied Physiology. 108, 4, p. 830-7 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  68. Published

    Nutrition and aging

    Cheng, W., Bohr, Vilhelm & de Cabo, R., 1 Apr 2010, In: Mechanisms of Ageing and Development. 131, 4, p. 223-4 2 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  69. Published

    Depletion of WRN protein causes RACK1 to activate several protein kinase C isoforms

    Massip, L., Garand, C., Labbé, A., Perreault, E., Turaga, R. V. N., Bohr, Vilhelm & Lebel, M., 11 Mar 2010, In: Oncogene. 29, 10, p. 1486-97 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  70. Published

    Roles of Werner syndrome protein in protection of genome integrity

    Rossi, M. L., Ghosh, A. K. & Bohr, Vilhelm, 2 Mar 2010, In: DNA Repair. 9, 3, p. 331-44 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  71. Published

    Impact papers on aging in 2009

    Blagosklonny, M. V., Campisi, J., Sinclair, D. A., Bartke, A., Blasco, M. A., Bonner, W. M., Bohr, V. A., Brosh, R. M., Brunet, A., Depinho, R. A., Donehower, L. A., Finch, C. E., Finkel, T., Gorospe, M., Gudkov, A. V., Hall, M. N., Hekimi, S., Helfand, S. L., Karlseder, J., Kenyon, C. & 15 others, Kroemer, G., Longo, V., Nussenzweig, A., Osiewacz, H. D., Peeper, D. S., Rando, T. A., Rudolph, K. L., Sassone-Corsi, P., Serrano, M., Sharpless, N. E., Skulachev, V. P., Tilly, J. L., Tower, J., Verdin, E. & Vijg, J., 1 Mar 2010, In: Aging. 2, 3, p. 111-21 11 p.

    Research output: Contribution to journalReviewResearch

  72. Published

    Time trends in physical activity in leisure time in the Danish population from 1987 to 2005

    Petersen, C. B., Thygesen, L. C., Helge, Jørn Wulff, Grønbaek, M. & Tolstrup, J. S., 1 Mar 2010, In: Scandinavian Journal of Public Health. 38, 2, p. 121-8 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  73. Published

    Regional anatomic differences in skeletal muscle mitochondrial respiration in type 2 diabetes and obesity

    Rabøl, R., Larsen, Steen, Højberg, P. M. V., Almdal, Thomas Peter, Boushel, R. C., Haugaard, Steen Bendix, Andersen, J. L., Madsbad, Sten & Dela, Flemming, 1 Feb 2010, In: Journal of Clinical Endocrinology and Metabolism. 95, 2, p. 857-63 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  74. Published

    Earl R. Stadtman

    Levine, R. L. & Bohr, Vilhelm, 1 Jan 2010, In: Mechanisms of Ageing and Development. 131, 1, p. 1

    Research output: Contribution to journalJournal articleResearchpeer-review

  75. Published

    Cardiac and metabolic changes in long-term high fructose-fat fed rats with severe obesity and extensive intramyocardial lipid accumulation

    Axelsen, L. N., Lademann, J. B., Petersen, J. S., von Holstein-Rathlou, Niels-Henrik, Ploug, Thorkil, Prats Gavalda, Clara, Pedersen, H. D. & Kjølbye, A. L., 2010, In: American Journal of Physiology: Regulatory, Integrative and Comparative Physiology. 298, 6, p. R1560-70

    Research output: Contribution to journalJournal articleResearchpeer-review

  76. Published

    FAT/CD36 is localized in sarcolemma and in vesicle-like structures in subsarcolemma regions but not in mitochondria

    Jeppesen, J., Mogensen, M., Prats Gavalda, Clara, Sahlin, K., Madsen, K. & Kiens, Bente, 2010, In: Journal of Lipid Research. 51, 6, p. 1504-1512 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  77. Published

    Fat oxidation at rest predicts peak fat oxidation during exercise and metabolic phenotype in overweight men

    Rosenkilde, M., Nordby, P., Nielsen, L. B., Stallknecht, Bente Merete & Helge, Jørn Wulff, 2010, In: International Journal of Obesity. 34, 5, p. 871-7 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  78. Published

    Increased rate of whole body lipolysis before and after 9 days of bed rest in healthy young men born with low birth weight

    Alibegovic, A. C., Hojbjerre, L., Sonne, M., van Hall, Gerrit, Alsted, T. J., Kiens, Bente, Stallknecht, Bente Merete, Dela, Flemming & Vaag, Allan, 2010, In: American Journal of Physiology: Endocrinology and Metabolism. 298, 3, p. E555-E564 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  79. Published

    Intake of total dietary sugar and fibre is associated with insulin resistance among Danish 8-10- and 14-16-year-old girls but not boys. European Youth Heart Studies I and II

    Kynde, I., Johnsen, N. F., Wedderkopp, N., Bygbjerg, Ib Christian, Helge, Jørn Wulff & Heitmann, Berit, 2010, In: Public Health Nutrition. 13, 10, p. 1669-74

    Research output: Contribution to journalJournal articleResearchpeer-review

  80. Published

    Kost, motion og sport

    Helge, Jørn Wulff, McDonald, C. & Kjær, Michael, 2010, Menneskets Ernæring. 3 ed. København: Munksgaard , p. 401-424 24 p.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterCommunication

  81. Published

    Leptin receptor 170 kDa (OB-R170) protein expression is reduced in obese human skeletal muscle: a potential mechanism of leptin resistance

    Fuentes, T., Ara, I., Guadalupe-Grau, A., Larsen, S., Stallknecht, Bente Merete, Olmedillas, H., Santana, A., Helge, Jørn Wulff, Calbet, J. A. L. & Guerra, B., 2010, In: Experimental Physiology. 95, 1, p. 160-71 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  82. Published

    Mitochondrial helicases and mitochondrial genome maintenance

    de Souza-Pinto, N. C., Aamann, M. D., Kulikowicz, T., Stevnsner, T. V. & Bohr, Vilhelm, 2010, In: Mechanisms of Ageing and Development. 131, 7-8, p. 503-10 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  83. Published

    Mitochondrial respiration in subcutaneous and visceral adipose tissue from patients with morbid obesity

    Kraunsøe, R., Boushel, R. C., Hansen, C. N., Schjerling, Peter, Qvortrup, Klaus, Støckel, M., Mikines, K. J. & Dela, Flemming, 2010, In: Journal of Physiology. 588, 12, p. 2023-2032 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  84. Published

    Muscle ceramide content in man is higher in type I than type II fibers and not influenced by glycogen content

    Nordby, P., Prats Gavalda, Clara, Kristensen, D., Ekroos, K., Forsberg, G., Andersen, J. L., Ploug, Thorkil, Dela, Flemming, Storlien, L. & Helge, Jørn Wulff, 2010, In: Journal of Applied Physiology. 109, 5, p. 935-943 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  85. Published

    Neurons efficiently repair glutamate-induced oxidative DNA damage by a process involving CREB-mediated up-regulation of apurinic endonuclease 1

    Yang, J., Tadokoro, T., Keijzers, G., Mattson, M. P. & Bohr, Vilhelm, 2010, In: Journal of Biological Chemistry. 285, 36, p. 28191-9 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  86. 2009
  87. Published

    The recombination protein RAD52 cooperates with the excision repair protein OGG1 for the repair of oxidative lesions in mammalian cells

    de Souza-Pinto, N. C., Maynard, S., Hashiguchi, K., Hu, J., Muftuoglu, M. & Bohr, Vilhelm, Aug 2009, In: Molecular and Cellular Biology. 29, 16, p. 4441-54 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  88. Published

    Sex hormone-binding globulin levels predict insulin sensitivity, disposition index, and cardiovascular risk during puberty

    Sørensen, K., Aksglaede, L., Munch-Andersen, T., Aachmann-Andersen, N. J., Petersen, Jørgen Holm, Hilsted, Linda, Helge, Jørn Wulff & Juul, Anders, 1 May 2009, In: Diabetes Care. 32, 5, p. 909-14 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  89. Published

    Cockayne syndrome group B protein stimulates repair of formamidopyrimidines by NEIL1 DNA glycosylase

    Muftuoglu, M., de Souza-Pinto, N. C., Dogan, A., Aamann, M., Stevnsner, T., Rybanska, I., Kirkali, G., Dizdaroglu, M. & Bohr, Vilhelm, Apr 2009, In: Journal of Biological Chemistry. 284, 14, p. 9270-9 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  90. Published

    Base excision repair of oxidative DNA damage and association with cancer and aging

    Maynard, S., Schurman, S. H., Harboe, C., de Souza-Pinto, N. C. & Bohr, Vilhelm, 1 Jan 2009, In: Carcinogenesis. 30, 1, p. 2-10 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  91. Published

    SIRT6 stabilizes DNA-dependent protein kinase at chromatin for DNA double-strand break repair

    McCord, R. A., Michishita, E., Hong, T., Berber, E., Boxer, L. D., Kusumoto, R., Guan, S., Shi, X., Gozani, O., Burlingame, A. L., Bohr, Vilhelm & Chua, K. F., 1 Jan 2009, In: Aging. 1, 1, p. 109-21 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  92. Published

    Are substrate use during exercise and mitochondrial respiratory capacity decreased in arm and leg muscle in type 2 diabetes?

    Larsen, Steen, Ara, I., Rabøl, R., Andersen, J. L., Boushel, R., Dela, Flemming & Helge, Jørn Wulff, 2009, In: Diabetologia. 52, 7, p. 1400-8 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  93. Published

    Cardiovascular disease markers in type 2 diabetes: the effects of a moderate home-based exercise training programme

    Scheede-Bergdahl, C., Benee Olsen, D., Reving, D., Boushel, R. & Dela, Flemming, 2009, In: Diabetes and Vascular Disease Research. 6, 4, p. 291-6 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  94. Published

    Diminished insulin-mediated forearm blood flow and muscle glucose uptake in young men with low birth weight

    Sonne, M. P., Højbjerre, L., Alibegovic, A. C., Vaag, Allan, Stallknecht, Bente Merete & Dela, Flemming, 2009, In: Journal of Vascular Research. 47, 2, p. 139-47 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  95. Published

    Dual regulation of muscle glycogen synthase during exercise by activation and compartmentalization

    Prats Gavalda, Clara, Helge, Jørn Wulff, Nordby, P., Qvortrup, Klaus, Ploug, Thorkil, Dela, Flemming & Wojtaszewski, Jørgen F P, 2009, In: Journal of Biological Chemistry. 284, 23, p. 15692-15700 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  96. Published

    Effect of Hyperglycemia on Mitochondrial Respiration in Type 2 Diabetes

    Rabøl, R., Højberg, P. M. V., Almdal, Thomas Peter, Boushel, R., Haugaard, S. B., Madsbad, Sten, Dela, Flemming, Rabøl, R., Højberg, P. M. V., Almdal, T., Boushel, R., Haugaard, S. B., Madsbad, Sten & Dela, F., 2009, In: Journal of Clinical Endocrinology and Metabolism. 94, 4, p. 1372-78

    Research output: Contribution to journalJournal articleResearchpeer-review

  97. Published

    Effects of a 14-month low-cost maintenance training program in patients with chronic systolic heart failure: a randomized study

    Prescott, Eva, Hjardem-Hansen, R., Dela, Flemming, Orkild, B., Teisner, A. & Nielsen, H., 2009, In: European Journal of Cardiovascular Prevention & Rehabilitation. 16, 4, p. 430-7 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  98. Published

    Exercise training in older patients with systolic heart failure: Adherence, exercise capacity, inflammation and glycemic control

    Prescott, Eva, Hjardem-Hansen, R., Dela, Flemming, Teisner, A. & Nielsen, H., 2009, In: Scandinavian Cardiovascular Journal. 43, p. 249-255 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  99. Published

    Fysisk traening ved type 2-diabetes. Er tre gange ti minutter om dagen bedre end 30 minutter?--sekundaerpublikation

    Dahl-Petersen, I., Eriksen, L., Haugaard, S. B. & Dela, Flemming, 2009, In: Ugeskrift for læger. 171, 11, p. 878-80 2 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  100. Published

    Hypoadiponectinemia in overweight children contributes to a negative metabolic risk profile 6 years later

    Kynde, I., Heitmann, B. L., Bygbjerg, Ib Christian, Andersen, L. B. & Helge, Jørn Wulff, 2009, In: Metabolism - Clinical and Experimental. 58, 12, p. 1817-24 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  101. Published

    Impact of 9 days of bed rest on hepatic and peripheral insulin action, insulin secretion, and whole-body lipolysis in healthy young male offspring of patients with type 2 diabetes

    Alibegovic, A. C., Højbjerre, L., Sonne, M. P., van Hall, G., Stallknecht, Bente Merete, Dela, Flemming & Vaag, Allan, 2009, In: Diabetes. 58, 12, p. 2749-56 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  102. Published

    Impact of the growth hormone receptor exon 3 deletion gene polymorphism on glucose metabolism, lipids, and insulin-like growth factor-I levels during puberty

    Sørensen, K., Aksglaede, L., Munch-Andersen, T., Aachmann-Andersen, N. J., Leffers, H., Helge, Jørn Wulff, Hilsted, Linda & Juul, Anders, 2009, In: Journal of Clinical Endocrinology and Metabolism. 94, 8, p. 2966-9 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  103. Published

    Impaired endothelial function and insulin action in first-degree relatives of patients with type 2 diabetes mellitus

    Sonne, M. P., Højbjerre, L., Alibegovic, A. A., Vaag, Allan, Stallknecht, Bente Merete & Dela, Flemming, 2009, In: Metabolism - Clinical and Experimental. 58, 1, p. 93-101 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  104. Published

    Improved glycaemic control decreases inner mitochondrial membrane leak in type 2 diabetes

    Rabøl, R., Højberg, P. M. V., Almdal, Thomas Peter, Boushel, R., Haugaard, S. B., Madsbad, Sten, Dela, Flemming, Rabøl, R., Højberg, P. M. V., Almdal, T., Boushel, R., Haugaard, S. B., Madsbad, Sten & Dela, F., 2009, In: Diabetic Medicine. 11, 4, p. 355-60 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  105. Published

    Insulin and non-insulin mediated vasodilation and glucose uptake in patients with type 2 diabetes

    Scheede-Bergdahl, C., Olsen, D. B., Reving, D., Boushel, R. & Dela, Flemming, 2009, In: Diabetes Research and Clinical Practice. 85, 3, p. 243-51 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review