- 2017
- Published
miRNAs in Human Subcutaneous Adipose Tissue: Effects of Weight Loss Induced by Hypocaloric Diet and Exercise
Kristensen, M. M., Davidsen, P. K., Vigelso, A., Hansen, C. N., Jensen, Lars Juhl, Jessen, N., Bruun, J. M., Dela, Flemming & Helge, Jørn Wulff, Mar 2017, In: Obesity. 25, 3, p. 572-580 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Study protocol; Thyroid hormone Replacement for Untreated older adults with Subclinical hypothyroidism: a randomised placebo controlled Trial (TRUST)
Stott, D. J., Gussekloo, J., Kearney, P. M., Rodondi, N., Westendorp, R. G. J., Mooijaart, S. P., Kean, S., Quinn, T. J., Sattar, N., Hendry, K., Du Puy, R., Den Elzen, W. P. J., Poortvliet, R. K. E., Smit, J. W. A., Jukema, J. W., Dekkers, O. M., Blum, M., Collet, T-H., McCarthy, V., Hurley, C. & 5 others, , 3 Feb 2017, In: B M C Endocrine Disorders. 17, p. 1-17 17 p., 6.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Repeated Prolonged Exercise Decreases Maximal Fat Oxidation in Older Men
Morville, T., Rosenkilde, M., Munch-Andersen, T., Riis Andersen, P., Groenbæk, K. K., Helbo, S., Kristensen, M., Vigelsø, A., Mattsson, N., Kruuse Rasmusen, H., Guadalupe-Grau, A., Fago, A., Neigaard Hansen, C., Twelkmeyer, B., Løvind Andersen, J., Dela, Flemming & Helge, Jørn Wulff, Feb 2017, In: Medicine and Science in Sports and Exercise. 49, 2, p. 308-316 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
When Contact Is Not Enough: Affecting First Year Medical Students' Image towards Older Persons
Kusumastuti, S., van Fenema, E., Stratum, E. C. F. P., Achterberg, W., Lindenberg, J. & Westendorp, Rudi GJ, 20 Jan 2017, In: PLOS ONE. 12, 1, p. 1-15 15 p., e0169977.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Assessment of health status by molecular measures in adults ranging from middle-aged to old: Ready for clinical use?
Waaijer, M. E. C., Westendorp, Rudi GJ, Goldeck, D., Gunn, D. A., Pawelec, G., Stijntjes, M., Slagboom, P. E. & Maier, A. B., Jan 2017, In: Experimental Gerontology. 87, Part B, p. 175–181 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genome instability in Alzheimer disease
Hou, Y., Song, H., Croteau, D. L., Akbari, M. & Bohr, Vilhelm, Jan 2017, In: Mechanisms of Ageing and Development. 161, part A, p. 83-94 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
In Vitro and In Vivo Detection of Mitophagy in Human Cells, C. Elegans, and Mice
Fang, E. F., Palikaras, K., Sun, N., Fivenson, E. M., Spangler, R. D., Kerr, J. S., Cordonnier, S. A., Hou, Y., Dombi, E., Kassahun, H., Tavernarakis, N., Poulton, J., Nilsen, H. & Bohr, Vilhelm, 2017, In: Journal of Visualized Experiments. 129, e56301.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Anthropometry, DXA and leptin reflect subcutaneous but not visceral abdominal adipose tissue by MRI in 197 healthy adolescents
Tinggaard, J., Hagen, C. P., Christensen, A. N., Mouritsen, A., Mieritz, M. G., Wohlfahrt-Veje, C., Helge, Jørn Wulff, Beck, T. N., Fallentin, E., Larsen, R., Jensen, R. B., Juul, Anders & Main, Katharina Maria, 2017, In: Pediatric Research. 82, p. 620-628Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cockayne syndrome: Clinical features, model systems and pathways
Karikkineth, A. C., Scheibye-Knudsen, Morten, Fivenson, E., Croteau, D. L. & Bohr, Vilhelm, 2017, In: Ageing Research Reviews. 33, p. 3-17Research output: Contribution to journal › Review › Research › peer-review
- Published
Corporate culture: research can benefit
Westendorp, Rudi GJ & Wewer, Ulla M., 2017, In: Nature. 542, 7641, 1 p., 295.Research output: Contribution to journal › Journal article › Communication
- Published
Lack of effect of prolonged treatment with liraglutide on cardiac remodeling in rats after acute myocardial infarction
Kyhl, K., Lønborg, Jacob Thomsen, Hartmann, Bolette, Kissow, Hannelouise, Poulsen, Steen Seier, El Ali, Henrik H., Kjær, Andreas, Dela, Flemming, Engstrøm, Thomas & Treiman, M., 2017, In: Peptides. 93, p. 1-12Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Maximal Fat Oxidation is Related to Performance in an Ironman Triathlon
Frandsen, J., Vest, S. D., Dela, Flemming & Helge, Jørn Wulff, 2017, In: International Journal of Sports Medicine. 38, 13, p. 975-982Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mitophagy and Alzheimer's Disease: Cellular and Molecular Mechanisms
Kerr, J. S., Adriaanse, B. A., Greig, N. H., Mattson, M. P., Cader, M. Z., Bohr, Vilhelm & Fang, E. F., 2017, In: Trends in Neurosciences. 40, 3, p. 151-166 16 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Mitophagy in neurodegeneration and aging
Fivenson, E. M., Lautrup, S., Sun, N., Scheibye-Knudsen, Morten, Stevnsner, T., Nilsen, H., Bohr, Vilhelm & Fang, E. F., 2017, In: Neurochemistry International. 109, p. 202-209Research output: Contribution to journal › Review › Research › peer-review
- Published
NAD+ in Aging: Molecular Mechanisms and Translational Implications
Fang, E. F., Lautrup, S., Hou, Y., Demarest, T. G., Croteau, D. L., Mattson, M. P. & Bohr, Vilhelm, 2017, In: Trends in Molecular Medicine. 23, 10, p. 899-916 18 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Pre-ischaemic mitochondrial substrate constraint by inhibition of malate-aspartate shuttle preserves mitochondrial function after ischaemia–reperfusion
Jespersen, N. R., Yokota, T., Støttrup, N. B., Bergdahl, A., Pælestik, K. B., Povlsen, J. A., Dela, Flemming & Bøtker, H. E., 2017, In: Journal of Physiology. 595, 12, p. 3765-3780 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Relationship between volition, physical activity and weight loss maintenance: Study rationale, design, methods and baseline characteristics
Dandanell, S., Elbe, A., Pfister, G. U., Elsborg, P. & Helge, Jørn Wulff, 2017, In: Scandinavian Journal of Public Health. 45, 3, p. 299-304 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Repeated lifestyle interventions lead to progressive weight loss: A retrospective review chart study
Dandanell, S., Ritz, C., Verdich, E., Dela, Flemming & Helge, Jørn Wulff, 2017, In: Scandinavian Journal of Public Health. 45, 3, p. 305-313 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Rev1 contributes to proper mitochondrial function via the PARP-NAD(+)-SIRT1-PGC1 alpha axis
Fakouri, N. B., Durhuus, J. A., Regnell, C. E., Angleys, M., Desler, Claus, Hasan-Olive, M., Martin-Pardillos, A., Tsaalbi-Shtylik, A., Thomsen, Kirsten Joan, Lauritzen, Martin, Bohr, Vilhelm, de Wind, N., Bergersen, L. H. & Rasmussen, Lene Juel, 2017, In: Scientific Reports. 7, 14 p., 12480.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Shift work, long working hours, and later risk of dementia: A long-term follow-up of the Copenhagen Male Study.
Nabe-Nielsen, Kirsten, Garde, A. H., Ahmed, K. I., Gyntelberg, F., Mortensen, Erik Lykke, Phung, T. K. T., Rod, Naja Hulvej, Waldemar, Gunhild, Westendorp, Rudi GJ & Hansen, Åse Marie, 2017, In: Scand J Work Environ Health. 43, 6, p. 569-577 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Temporary impact of blood donation on physical performance and hematologic variables in women
Stangerup, I., Kramp, N. L., Ziegler, A. K., Dela, Flemming, Magnussen, K. & Helge, Jørn Wulff, 2017, In: Transfusion. 57, 8, p. 1905-1911Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Thyroid Function Within the Normal Range, Subclinical Hypothyroidism and the Risk of Atrial Fibrillation
Baumgartner, C., da Costa, B. R., Collet, T-H., Feller, M., Floriani, C., Bauer, D. C., Cappola, A. R., Heckbert, S. R., Ceresini, G., Gussekloo, J., den Elzen, W. P. J., Peeters, R. P., Luben, R., Völzke, H., Dörr, M., Walsh, J. P., Bremner, A., Iacoviello, M., Macfarlane, P., Heeringa, J. & 7 others, , 2017, In: Circulation. 136, 22, p. 2100-2116 17 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Tomatidine enhances lifespan and healthspan in C. elegans through mitophagy induction via the SKN-1/Nrf2 pathway
Fang, E. F., Waltz, T. B., Kassahun, H., Lu, Q., Kerr, J. S., Morevati, M., Fivenson, E. M., Wollman, B. N., Marosi, K., Wilson, M. A., Iser, W. B., Eckley, D. M., Zhang, Y., Lehrmann, E., Goldberg, I. G., Scheibye-Knudsen, Morten, Mattson, M. P., Nilsen, H., Bohr, Vilhelm & Becker, K. G., 2017, In: Scientific Reports. 7, 46208.Research output: Contribution to journal › Journal article › Research › peer-review
- 2016
- Published
How older persons explain why they became victims of abuse
Mysyuk, Y., Westendorp, Rudi GJ & Lindenberg, J., 5 Dec 2016, In: Age and Ageing. 45, 5, p. 696-702 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A ketogenic diet accelerates neurodegeneration in mice with induced mitochondrial DNA toxicity in the forebrain
Lauritzen, K. H., Hasan-Olive, M. M., Regnell, C. E., Kleppa, L., Scheibye-Knudsen, Morten, Gjedde, Albert, Klungland, A., Bohr, Vilhelm, Storm-Mathisen, J. & Bergersen, L. H., Dec 2016, In: Neurobiology of Aging. 48, p. 34-47Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cardiorespiratory fitness in 16 025 adults aged 18-91 years and associations with physical activity and sitting time
Eriksen, L., Grønbæk, M., Helge, Jørn Wulff & Tolstrup, J. S., Dec 2016, In: Scandinavian Journal of Medicine & Science in Sports. 26, 12, p. 1435-1443 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Growth hormone secretion is diminished and tightly controlled in humans enriched for familial longevity
van der Spoel, E., Jansen, S. W., Akintola, A. A., Ballieux, B. E., Cobbaert, C. M., Slagboom, P. E., Blauw, G. J., Westendorp, Rudi GJ, Pijl, H., Roelfsema, F. & van Heemst, D., Dec 2016, In: Aging Cell. 15, 6, p. 1126–1131 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Increased post-operative cardiopulmonary fitness in gastric bypass patients is explained by weight loss
Lund, M. T., Hansen, M., Wimmelmann, Cathrine Lawaetz, Taudorf, L. R., Helge, Jørn Wulff, Mortensen, Erik Lykke & Dela, Flemming, Dec 2016, In: Scandinavian Journal of Medicine & Science in Sports. 26, 12, p. 1428-1434 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Meta-analysis of genome-wide association studies of HDL cholesterol response to statins
Postmus, I., Warren, H. R., Trompet, S., Arsenault, B. J., Avery, C. L., Bis, J. C., Chasman, D. I., de Keyser, C. E., Deshmukh, H. A., Evans, D. S., Feng, Q., Li, X., Smit, R. A. J., Smith, A. V., Sun, F., Taylor, K. D., Arnold, A. M., Barnes, M. R., Barratt, B. J., Betteridge, J. & 68 others, , Dec 2016, In: Journal of Medical Genetics. 53, 12, p. 835-845 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effekt af livsstilsændringer på vægttab og vedligeholdelse af vægttab
Lionett, S. B., Helge, Jørn Wulff, Dela, Flemming & Jørgensen, S. D., 30 Nov 2016, In: Ugeskrift for Laeger. 178, 22, p. 2-6 5 p., 2016;178:V07160509.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Impact of physical and mental health on life satisfaction in old age: a population based observational study
Puvill, T., Lindenberg, J., de Craen, A. J. M., Slaets, J. P. J. & Westendorp, Rudi GJ, 25 Nov 2016, In: B M C Geriatrics. 16, p. 1-9 9 p., 194.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Familial Longevity Is Not Associated with Major Differences in the Hypothalamic–Pituitary–Gonadal Axis in Healthy Middle-Aged Men
van der Spoel, E., Roelfsema, F., Jansen, S. W., Akintola, A. A., Ballieux, B. E., Cobbaert, C. M., Blauw, G. J., Slagboom, P. E., Westendorp, Rudi GJ, Piji, H. & van Heemst, D., 9 Nov 2016, In: Frontiers in Endocrinology. 7, p. 1-7 7 p., 143.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cockayne syndrome group A and B proteins converge on transcription-linked resolution of non-B DNA
Scheibye-Knudsen, M., Tseng, A., Jensen, M. B., Scheibye-Alsing, K., Fang, E. F., Iyama, T., Bharti, S. K., Marosi, K., Froetscher, L., Kassahun, H., Eckley, D. M., Maul, R. W., Bastian, P., De, S., Ghosh, S., Nilsen, H., Goldberg, I. G., Mattson, M. P., Wilson, D. M. . III., Brosh, R. M. . J. & 2 others, , 1 Nov 2016, In: National Academy of Sciences. Proceedings. 113, 44, p. 12502-12507Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Perspectives on the Etiology of Violence in Later Life
Mysyuk, Y., Westendorp, Rudi GJ & Lindenberg, J., 1 Nov 2016, In: Journal of Interpersonal Violence. 31, 18, p. 3039-3062 24 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Exercise promotes IL-6 release from legs in older men with minor response to unilateral immobilization
Reihmane, D., Gram, M., Vigelsø Hansen, A., Helge, Jørn Wulff & Dela, Flemming, Nov 2016, In: European Journal of Sport Science. 16, 8, p. 1039-1046 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Successful ageing: A study of the literature using citation network analysis
Kusumastuti, S., Derks, M. G. M., Tellier, S., Di Nucci, Ezio, Lund, Rikke, Mortensen, Erik Lykke & Westendorp, Rudi GJ, Nov 2016, In: Maturitas. 93, p. 4-12 9 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Thyroid Function within the Reference Range and the Risk of Stroke: An Individual Participant Data Analysis
Chaker, L., Baumgartner, C., den Elzen, W. P. J., Collet, T-H., Ikram, M. A., Blum, M. R., Dehghan, A., Drechsler, C., Luben, R. N., Portegies, M. L. P., Iervasi, G., Medici, M., Stott, D. J., Dullaart, R. P., Ford, I., Bremner, A., Newman, A. B., Wanner, C., Sgarbi, J. A., Dörr, M. & 22 others, , Nov 2016, In: The Journal of Clinical Endocrinology & Metabolism. 101, 11, p. 4270 – 4282 13 p., jc20162255.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
NAD(+) Replenishment Improves Lifespan and Healthspan in Ataxia Telangiectasia Models via Mitophagy and DNA Repair
Fang, E. F., Kassahun, H., Croteau, D. L., Scheibye-Knudsen, M., Marosi, K., Lu, H., Shamanna, R. A., Kalyanasundaram, S., Bollineni, R. C., Wilson, M. A., Iser, W. B., Wollman, B. N., Morevati, M., Li, J., Kerr, J. S., Lu, Q., Waltz, T. B., Tian, J., Sinclair, D. A., Mattson, M. P. & 2 others, , 11 Oct 2016, In: Cell Metabolism. 24, 4, p. 566-581 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Actovegin, a non-prohibited drug increases oxidative capacity in human skeletal muscle
Søndergård, S. D., Dela, Flemming, Helge, Jørn Wulff & Larsen, Steen, Oct 2016, In: European Journal of Sport Science. 16, 7, p. 801-807 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Associations of Various Health-Ratings with Geriatric Giants, Mortality and Life Satisfaction in Older People
Puvill, T., Lindenberg, J., Gussekloo, J., de Craen, A. J. M., Slaets, J. P. J. & Westendorp, Rudi GJ, 22 Sep 2016, In: P L o S One. 11, 9, p. 1-13 13 p., e0163499.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
New horizons: Reablement - supporting older people towards independence
Aspinal, F., Glasby, J., Rostgaard, T., Tuntland, H. & Westendorp, Rudi GJ, 5 Sep 2016, In: Age and Ageing. 45, 5, p. 574-578 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The development, implementation and evaluation of a transitional care programme to improve outcomes of frail older patients after hospitalisation
Heim, N., Rolden, H., van Fenema, E. M., Weverling-Rijnsburger, A. W. E., Tuijl, J. P., Jue, P., Oleksik, A. M., de Craen, A. J. M., Mooijaart, S. P., Blauw, G. J., Westendorp, Rudi GJ, van der Mast, R. C. & van Everdinck, I. E. C., 5 Sep 2016, In: Age and Ageing. 45, 5, p. 642-651 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
High-sensitivity cardiac troponin T is associated with cognitive decline in older adults at high cardiovascular risk
Wijsman, L. W., de Craen, A. J., Trompet, S., Sabayan, B., Muller, M., Stott, D. J., Ford, I., Welsh, P., Westendorp, Rudi GJ, Jukema, J. W., Sattar, N. & Mooijaart, S. P., Sep 2016, In: European Journal of Preventive Cardiology. 23, 13, p. 1383-1392 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Early and extraordinary peaks in physical performance come with a longevity cost
van de Vijver, P. L., van Bodegom, D. & Westendorp, Rudi GJ, 19 Aug 2016, In: Aging. 8, 8, p. 1822-1829 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Hepatic fat content decreases with 3 weeks of intermittent fasting in obese patients with and without type 2 diabetes
Ingersen, Arthur, Helset, H., Skaaby, Stinna, Calov, M., Chabanova, E., Helge, Jørn Wulff & Dela, Flemming, Aug 2016, In: Diabetologia. 59, S1, p. S78-S78Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
Insulin Plays a Permissive Role for the Vasoactive Effect of GIP Regulating Adipose Tissue Metabolism in Humans
Asmar, M., Simonsen, L., rck626, rck626, Holst, Jens Juul, Dela, Flemming & Bülow, J., Aug 2016, In: Journal of Clinical Endocrinology and Metabolism. 101, 8, p. 3155-62 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
P16INK4a Positive Cells in Human Skin Are Indicative of Local Elastic Fiber Morphology, Facial Wrinkling, and Perceived Age
Waaijer, M. E. C., Gunn, D. A., Adams, P. D., Pawlikowski, J. S., Griffiths, C. E. M., van Heemst, D., Slagboom, P. E., Westendorp, Rudi GJ & Maier, A. B., Aug 2016, In: Journals of Gerontology. Series A: Biological Sciences & Medical Sciences. 71, 8, p. 1022-1028 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Secreted microvesicular miR-31 inhibits osteogenic differentiation of mesenchymal stem cells
Weilner, S., Schraml, E., Wieser, M., Messner, P., Schneider, K., Wassermann, K., Micutkova, L., Fortschegger, K., Maier, A. B., Westendorp, Rudi GJ, Resch, H., Wolbank, S., Redl, H., Jansen-Dürr, P., Pietschmann, P., Grillari-Voglauer, R. & Grillari, J., Aug 2016, In: Aging Cell. 15, 4, p. 744–754 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Visit-to-visit blood pressure variability and future functional decline in old age
Ogliari, G., Smit, R. A. J., Westendorp, Rudi GJ, Jukema, J. W., de Craen, A. J. M. & Sabayan, B., Aug 2016, In: Journal of Hypertension. 34, 8, p. 1544–1550 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effects of a 12-week alpine skiing intervention on endothelial progenitor cells, peripheral arterial tone and endothelial biomarkers in the elderly
Niederseer, D., Steidle-Kloc, E., Mayr, M., Müller, E. E., Cadamuro, J., Patsch, W., Dela, Flemming, Müller, E. & Niebauer, J., 1 Jul 2016, In: International Journal of Cardiology. 214, p. 343-347 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
RECQL4 Promotes DNA End Resection in Repair of DNA Double-Strand Breaks
Lu, H., Shamanna, R. A., Keijzers, G., Anand, R., Rasmussen, Lene Juel, Cejka, P., Croteau, D. L. & Bohr, Vilhelm, 28 Jun 2016, In: Cell Reports. 16, 1, p. 161-173 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic variants determining survival and fertility in an adverse African environment: a population-based large-scale candidate gene association study
Koopman, J. J. E., Pijpe, J., Böhringer, S., van Bodegom, D., Eriksson, U. K., Sanchez-Faddeev, H., Ziem, J. B., Zwaan, B., Slagboom, P. E., de Knijff, P. & Westendorp, Rudi GJ, 27 Jun 2016, In: Aging. 8, 7, p. 1364-1383 20 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Acquired Localized Cutis Laxa due to Increased Elastin Turnover
Nygaard, R. H., Maynard, S., Schjerling, P., Kjær, M., Qvortrup, Klaus, Bohr, Vilhelm, Rasmussen, Lene Juel, Jemec, Gregor & Heidenheim, M., 14 Jun 2016, In: Case Reports in Dermatology. 8, 1, p. 42-51 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
An Emerging Epidemic of Noncommunicable Diseases in Developing Populations Due to a Triple Evolutionary Mismatch
Koopman, J. J. E., van Bodegom, D., Ziem, J. B. & Westendorp, Rudi GJ, Jun 2016, In: American Journal of Tropical Medicine and Hygiene. 94, 6, p. 1189-1192 4 p.Research output: Contribution to journal › Comment/debate › Research › peer-review
- Published
The effects of diet- and RYGB-induced weight loss on insulin sensitivity in obese patients with and without type 2 diabetes
Hansen, M., Lund, M. T., Jørgensen, A. L. K., Palsøe, M. K., van Hall, Gerrit, Helge, Jørn Wulff & Dela, Flemming, Jun 2016, In: Acta Diabetologica. 53, 3, p. 423–432 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Aerobic Exercise Training Increases Muscle Water Content in Obese Middle-Age Men
Mora-Rodríguez, R., Sanchez-Roncero, A., Fernández-Elías, V. E., Guadalupe-Grau, A., Ortega, J. F., Dela, Flemming & Helge, Jørn Wulff, May 2016, In: Medicine and Science in Sports and Exercise. 48, 5, p. 822-828 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Subclinical Thyroid Dysfunction and Depressive Symptoms among Elderly: A Prospective Cohort Study
Blum, M. R., Wijsman, L. W., Virgini, V. S., Bauer, D. C., den Elzen, W. P. J., Jukema, J. W., Buckley, B. M., de Craen, A. J. M., Kearney, P. M., Stott, D. J., Gussekloo, J., Westendorp, Rudi GJ, Mooijaart, S. P. & Rodondi, N., May 2016, In: Neuroendocrinology. 103, 3-4, p. 291-299 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Hepatic mitochondrial oxidative phosphorylation is normal in obese patients with and without type 2 diabetes
Lund, M. T., Kristensen, M. D., Hansen, M., Tveskov, L., Floyd, A. K., Støckel, M., Vainer, B., Poulsen, Steen Seier, Helge, Jørn Wulff, Prats Gavalda, Clara & Dela, Flemming, 6 Apr 2016, In: The Journal of Physiology. 594, 15, p. 4351-4358 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
An Internet-Based Physical Activity Intervention to Improve Quality of Life of Inactive Older Adults: A Randomized Controlled Trial
Broekhuizen, K., de Gelder, J., Wijsman, C. A., Wijsman, L. W., Westendorp, Rudi GJ, Verhagen, E., Slagboom, P. E., de Craen, A. J., van Mechelen, W., van Heemst, D., van der Ouderaa, F. & Mooijaart, S. P., Apr 2016, In: Journal of Medical Internet Research. 18, 4, p. 1-11 11 p., e74.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Calculating the Rate of Senescence From Mortality Data: An Analysis of Data From the ERA-EDTA Registry
Koopman, J. J. E., Rozing, M. P., Kramer, A., Abad, J. M., Finne, P., Heaf, J. G., Hoitsma, A. J., De Meester, J. M. J., Palsson, R., Postorino, M., Ravani, P., Wanner, C., Jager, K. J., van Bodegom, D. & Westendorp, Rudi GJ, Apr 2016, In: Journals of Gerontology. Series A: Biological Sciences & Medical Sciences. 71, 4, p. 468-474 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Disentangling rectangularization and life span extension with the moving rectangle method
Schalkwijk, F. H., Koopman, J. J. E., Ghariq, E., de Beer, J. A. A., van Bodegom, D. & Westendorp, Rudi GJ, Mar 2016, In: Annals of Epidemiology. 26, 3, p. 218-221.e2 6 p.Research output: Contribution to journal › Letter › Research › peer-review
- Published
Effects of immobilization and aerobic training on proteins related to intramuscular substrate storage and metabolism in young and older men
Vigelsø Hansen, A., Gram, M., Wiuff, C., Hansen, C. N., Prats Gavalda, Clara, Dela, Flemming & Helge, Jørn Wulff, Mar 2016, In: European Journal of Applied Physiology. 116, 3, p. 481-494 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
DNA damage markers in dermal fibroblasts in vitro reflect chronological donor age
Waaijer, M. E. C., Croco, E., Westendorp, Rudi GJ, Slagboom, P. E., Sedivy, J. M., Lorenzini, A. & Maier, A. B., 30 Jan 2016, In: Aging. 8, 1, p. 147-155 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Older persons' definitions and explanations of elder abuse in the Netherlands
Mysyuk, Y., Westendorp, Rudi GJ & Lindenberg, J., 5 Jan 2016, In: Journal of Elder Abuse & Neglect. 28, 2, p. 95-113 19 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effect of regional muscle location but not adiposity on mitochondrial biogenesis-regulating proteins
Ponce-González, J. G., Ara, I., Larsen, Steen, Guerra, B., Calbet, J. A. L. & Helge, Jørn Wulff, Jan 2016, In: European Journal of Applied Physiology. 116, 1, 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Football training in men with prostate cancer undergoing androgen deprivation therapy: activity profile and short-term skeletal and postural balance adaptations
Uth, J., Hornstrup, T., Christensen, J. F., Christensen, Karl Bang, Jørgensen, N. R., Helge, Eva Wulff, Schmidt, J. F., Brasso, K., Helge, Jørn Wulff, Jakobsen, M. D., Andersen, L. L., Rørth, M. R., Midtgaard, Julie & Krustrup, P., 2016, In: European Journal of Applied Physiology. 116, 3, p. 471-480 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Higher muscle content of perilipin 5 and endothelial lipase protein in trained than untrained middle-aged men
Vigelsø Hansen, A., Prats Gavalda, Clara, Ploug, Thorkil, Dela, Flemming & Helge, Jørn Wulff, 2016, In: Physiological Research. 65, 2, p. 293-302 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
LIFESTAT – Living with statins: An interdisciplinary project on the use of statins as a cholesterol-lowering treatment and for cardiovascular risk reduction
Christensen, Christa Lykke, Helge, Jørn Wulff, Krasnik, Allan, Kriegbaum, Margit, Rasmussen, Lene Juel, Hickson, Ian David, Liisberg, Kasper Bering, Oxlund, Bjarke, Bruun, B., Lau, Sofie Rosenlund, Olsen, M. N. A., Andersen, John Sahl, Heltberg, Andreas Søndergaard, Kuhlman, A. C. B., Morville, T. H., Dohlmann, T. L., Larsen, Steen & Dela, Flemming, 2016, In: Scandinavian Journal of Public Health. 44, 5, p. 534-539 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Moving in extreme environments: extreme loading; carriage versus distance
Lucas, S. J. E., Helge, Jørn Wulff, Schütz, U. H. W., Goldman, R. F. & Cotter, J. D., 2016, In: Extreme Physiology & Medicine. 5, 14 p., 6.Research output: Contribution to journal › Review › Research › peer-review
- Published
Physiological responding to stress in middle-aged males enriched for longevity: a social stress study
Jansen, S. W. M., van Heemst, D., van der Grond, J., Westendorp, Rudi GJ & Oei, N. Y. L., 2016, In: Stress: The International Journal on the Biology of Stress . 19, 1, p. 28-36 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Positive effects of 1-year football and strength training on mechanical muscle function and functional capacity in elderly men
Sundstrup, E., Jakobsen, M. D., Andersen, L. L., Rostgaard Andersen, T., Randers, M. B., Helge, Jørn Wulff, Suetta, Charlotte, Schmidt, J. F., Bangsbo, Jens, Krustrup, P. & Aagaard, P., 2016, In: European Journal of Applied Physiology. 116, 6, p. 1127-1138 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Effect of Preoperative Type 2 Diabetes and Physical Fitness on Mental Health and Health-Related Quality of Life after Roux-en-Y Gastric Bypass
Wimmelmann, Cathrine Lawaetz, Lund, M. T., Hansen, M., Dela, Flemming & Mortensen, Erik Lykke, 2016, In: Journal of Obesity. 2016, p. 1-9 9 p., 3474816.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The effect of age and unilateral leg immobilization for 2 weeks on substrate utilization during moderate intensity exercise in human skeletal muscle
Vigelsø, A., Gram, M., Dybboe, R., Kuhlman, A. B., Prats Gavalda, Clara, Greenhaff, P. L., Constantin-Teodosiu, D., Birk, Jesper Bratz, Wojtaszewski, Jørgen F P, Dela, Flemming & Helge, Jørn Wulff, 2016, In: Journal of Physiology. 594, 8, p. 2339-2358 20 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Training Does Not Alter Muscle Ceramide and Diacylglycerol in Offsprings of Type 2 Diabetic Patients Despite Improved Insulin Sensitivity
Sogaard, D., Ostergard, T., Blachnio-Zabielska, A. U., Baranowski, M., Vigelsø Hansen, A., Andersen, J. L., Dela, Flemming & Helge, Jørn Wulff, 2016, In: Journal of Diabetes Research. 2016, 12 p., 2372741.Research output: Contribution to journal › Journal article › Research › peer-review
- 2015
- Published
The Trade-Off between Female Fertility and Longevity during the Epidemiological Transition in the Netherlands
Kaptijn, R., Thomese, F., Liefbroer, A. C., Van Poppel, F., Van Bodegom, D. & Westendorp, Rudi GJ, 17 Dec 2015, In: PloS one. 10, 12, p. 1-11 11 p., e0144353.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effects of angiotensin II receptor blockade on cerebral, cardiovascular, counter-regulatory, and symptomatic responses during hypoglycaemia in patients with type 1 diabetes
Færch, L. H., Thorsteinsson, B., Tarnow, L., Holst, Jens Juul, Kjær, T. W., Kanters, Jørgen K., Larroude, C., Dela, Flemming & Pedersen-Bjergaard, Ulrik, Dec 2015, In: Journal of the Renin-Angiotensin-Aldosterone System. 16, 4, p. 1036-1045 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Maintained peak leg and pulmonary VO2 despite substantial reduction in muscle mitochondrial capacity
Boushel, R., Gnaiger, E., Larsen, F. J., Helge, Jørn Wulff, González-Alonso, J., Ara, I., Munch-Andersen, T., van Hall, Gerrit, Søndergaard, H., Saltin, B. & Calbet, J. A. L., Dec 2015, In: Scandinavian Journal of Medicine & Science in Sports. 25 , Supplement 4, p. 135-143 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Ultrastructural myocardial changes in seven cats with spontaneous hypertrophic cardiomyopathy
Christiansen, L. B., Prats Gavalda, Clara, Hyttel, P. & Koch, Jørgen, Dec 2015, In: Journal of Veterinary Cardiology. 17 , Suppl. 1, p. S220-S232 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Seasonal Variation in Mortality, Medical Care Expenditure and Institutionalization in Older People: Evidence from a Dutch Cohort of Older Health Insurance Clients
Rolden, H. J. A., Rohling, J. H. T., van Bodegom, D. & Westendorp, Rudi GJ, 16 Nov 2015, In: PLOS ONE. 10, 11, p. 1-14 15 p., e0143154.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Association analysis of insulin-like growth factor-1 axis parameters with survival and functional status in nonagenarians of the Leiden Longevity Study
van der Spoel, E., Rozing, M. P., Houwing-Duistermaat, J. J., Slagboom, P. E., Beekman, M., de Craen, A. J. M., Westendorp, Rudi GJ & van Heemst, D., 12 Nov 2015, In: Aging. 7, 11, p. 956–963 8 p., PMC4694065.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Increased deoxythymidine triphosphate levels is a feature of relative cognitive decline
Desler, Claus, Frederiksen, J. H., Olsen, M. N. A., Maynard, S., Keijzers, G., Fagerlund, Birgitte, Mortensen, Erik Lykke, Osler, Merete, Lauritzen, Martin, Bohr, Vilhelm & Rasmussen, Lene Juel, Nov 2015, In: Mitochondrion. 25, p. 34-7 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Drug-Gene Interactions of Antihypertensive Medications and Risk of Incident Cardiovascular Disease: A Pharmacogenomics Study from the CHARGE Consortium
Bis, J. C., Sitlani, C., Irvin, R., Avery, C. L., Smith, A. V., Sun, F., Evans, D. S., Musani, S. K., Li, X., Trompet, S., Krijthe, B. P., Harris, T. B., Quibrera, P. M., Brody, J. A., Demissie, S., Davis, B. R., Wiggins, K. L., Tranah, G. J., Lange, L. A., Sotoodehnia, N. & 34 others, , 30 Oct 2015, In: PLOS ONE. 10, 10, p. 1-13 13 p., e0140496.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Resting heart rate, heart rate variability and functional decline in old age
Ogliari, G., Mahinrad, S., Stott, D. J., Jukema, J. W., Mooijaart, S. P., Macfarlane, P. W., Clark, E. N., Kearney, P. M., Westendorp, Rudi GJ, de Craen, A. J. M. & Sabayan, B., 20 Oct 2015, In: C M A J. 187, 15, p. E442-E449 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Accuracy of Continuous Glucose Monitoring Measurements in Normo-Glycemic Individuals
Akintola, A. A., Noordam, R., Jansen, S. W., de Craen, A. J., Ballieux, B. E., Cobbaert, C. M., Mooijaart, S. P., Pijl, H., Westendorp, Rudi GJ & van Heemst, D., 7 Oct 2015, In: PloS one. 10, 10, p. 1-13 13 p., e0139973.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Blood temperature and perfusion to exercising and non-exercising human limbs
González-Alonso, J., Calbet, J. A. L., Boushel, R., Helge, Jørn Wulff, Søndergaard, H., Munch-Andersen, T., van Hall, Gerrit, Mortensen, S. P. & Secher, Niels H., 1 Oct 2015, In: Experimental Physiology. 100, 10, p. 1118-1131 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Adipose tissue mitochondrial respiration and lipolysis before and after a weight loss by diet and RYGB
Hansen, M., Lund, M. T., Gregers, E., Kraunsøe, R., van Hall, Gerrit, Helge, Jørn Wulff & Dela, Flemming, Oct 2015, In: Obesity. 23, 10, p. 2022-2229 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
DNA Damage, DNA Repair, Aging, and Neurodegeneration
Maynard, S., Fang, E. F., Scheibye-Knudsen, Morten, Croteau, D. L. & Bohr, Vilhelm, Oct 2015, In: Cold Spring Harbor Perspectives in Medicine. 5, 10, a025130.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Defective mitochondrial respiration, altered dNTP pools and reduced AP endonuclease 1 activity in peripheral blood mononuclear cells of Alzheimer's disease patients
Maynard, S., Hejl, Anne-Mette, Dinh, T. T. S., Keijzers, G., Hansen, Åse Marie, Desler, Claus, Moreno-Villanueva, M., Bürkle, A., Rasmussen, Lene Juel, Waldemar, Gunhild & Bohr, Vilhelm, Oct 2015, In: Aging. 7, 10, p. 793-815 23 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effect of Discontinuation of Antihypertensive Treatment in Elderly People on Cognitive Functioning-the DANTE Study Leiden: A Randomized Clinical Trial
Moonen, J. E. F., Foster-Dingley, J. C., de Ruijter, W., van der Grond, J., Bertens, A. S., van Buchem, M. A., Gussekloo, J., Middelkoop, H. A., Wermer, M. J. H., Westendorp, Rudi GJ, de Craen, A. J. M. & van der Mast, R. C., Oct 2015, In: J A M A Internal Medicine. 175, 10, p. 1622-1630 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Familial Longevity Is Associated With Higher TSH Secretion and Strong TSH-fT3 Relationship
Jansen, S. W., Roelfsema, F., van der Spoel, E., Akintola, A. A., Postmus, I., Ballieux, B. E., Slagboom, P. E., Cobbaert, C. M., van der Grond, J., Westendorp, Rudi GJ, Pijl, H. & van Heemst, D., Oct 2015, In: Journal of Clinical Endocrinology and Metabolism. 100, 10, p. 3806-3813 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Effect of Reduced Physical Activity and Retraining on Blood Lipids and Body Composition in Young and Older Adult Men
Nørregaard, J., Gram, M., Vigelsø , A., Wiuff, C., Kuhlman, A. B., Helge, Jørn Wulff & Dela, Flemming, Oct 2015, In: Journal of Aging and Physical Activity. 23, 4, p. 489-495 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A novel method for determining human ex vivo submaximal skeletal muscle mitochondrial function
Hey-Mogensen, M., Gram, M., Jensen, M. B., Lund, M. T., Hansen, C. N., Scheibye-Knudsen, Morten, Bohr, Vilhelm & Dela, Flemming, 1 Sep 2015, In: The Journal of Physiology. 593, 17, p. 3991-4010 20 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Executive function, but not memory, associates with incident coronary heart disease and stroke
Rostamian, S., van Buchem, M. A., Westendorp, Rudi GJ, Jukema, J. W., Mooijaart, S. P., Sabayan, B. & de Craen, A. J. M., 1 Sep 2015, In: Neurology. 85, 9, p. 783-789 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Skeletal muscle mitochondrial H2O2 emission increases with immobilization and decreases after aerobic training in young and older men
Gram, M., Vigelsø, A., Yokota, T., Helge, Jørn Wulff, Dela, Flemming & Hey-Mogensen, M., 1 Sep 2015, In: The Journal of Physiology. 593, 17, p. 4011-4027 17 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Age- and Functional Status-Dependent Association Between Blood Pressure and Cognition: The Milan Geriatrics 75+ Cohort Study
Ogliari, G., Sabayan, B., Mari, D., Rossi, P. D., Lucchi, T. A., de Craen, A. J. M. & Westendorp, Rudi GJ, Sep 2015, In: Journal of the American Geriatrics Society. 63, 9, p. 1741-1748 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Subclinical hypothyroidism and cognitive function in people over 60 years: a systematic review and meta-analysis
Akintola, A. A., Jansen, S. W., van Bodegom, D., van der Grond, J., Westendorp, Rudi GJ, de Craen, A. J. M. & van Heemst, D., 11 Aug 2015, In: Frontiers in Aging Neuroscience. 7, p. 1-11 11 p., 150.Research output: Contribution to journal › Review › Research › peer-review
- Published
Slow mitochondrial repair of 5'-AMP renders mtDNA susceptible to damage in APTX deficient cells
Akbari, M., Sykora, P. & Bohr, Vilhelm, 10 Aug 2015, In: Scientific Reports. 5, 8 p., 12876 .Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Alpine Skiing With total knee ArthroPlasty (ASWAP): metabolism, inflammation, and skeletal muscle fiber characteristics
Kristensen, M., Pötzelsberger, B., Scheiber, P., Bergdahl, A., Hansen, C. N., Andersen, J. L., Narici, M., Salvioli, S., Conte, M., Müller, E. & Dela, Flemming, Aug 2015, In: Scandinavian Journal of Medicine & Science in Sports. 25, Supplement S2, p. 40-48 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Alpine Skiing With total knee ArthroPlasty (ASWAP): study design and intervention
Koesters, A., Poetzelsberger, B., Dela, Flemming, Dorn, U., Hofstaedter, T., Fink, C. & Mueller, E., Aug 2015, In: Scandinavian Journal of Medicine & Science in Sports. 25, Supplement S2, p. 3-9 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effect of moderate- versus high-intensity exercise on vascular function, biomarkers and quality of life in heart transplant recipients: A randomized, crossover trial
Dall, Christian Have, Gustafsson, F., Christensen, S. B., Dela, Flemming, Langberg, Henning & Prescott, Eva, Aug 2015, In: Journal of Heart and Lung Transplantation. 34, 8, p. 1033–1041 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
Most downloads
-
4320
downloads
The relationship between skeletal muscle mitochondrial citrate synthase activity and whole body oxygen uptake adaptations in response to exercise training.
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
4109
downloads
Meal induced gut hormone secretion is altered in aerobically trained compared to sedentary young healthy males
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
2124
downloads
Two weeks of metformin treatment enhances mitochondrial respiration in skeletal muscle of AMPK kinase dead but not wild type mice
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Latest publications
Antioxidant enzymes and Nrf2/Keap1 in human skeletal muscle: Influence of age, sex, adiposity and aerobic fitness
Research output: Contribution to journal › Journal article › Research › peer-review
Predicting mortality and visualizing health care spending by predicted mortality in Danes over age 65
Research output: Contribution to journal › Journal article › Research › peer-review
Accuracy of a Clinical Applicable Method for Prediction of VO2max Using Seismocardiography
Research output: Contribution to journal › Journal article › Research › peer-review