Individualized Health

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  1. Published

    14-3-3 checkpoint regulatory proteins interact specifically with DNA repair protein human exonuclease 1 (hEXO1) via a semi-conserved motif

    Andersen, S. D., Keijzers, G., Rampakakis, E., Engels, K., Luhn, P., El-Shemerly, M., Nielsen, Finn Cilius, Du, Y., May, A., Bohr, Vilhelm, Ferrari, S., Zannis-Hadjopoulos, M., Fu, H. & Rasmussen, Lene Juel, Mar 2012, In: D N A Repair. 11, 3, p. 267-77 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  2. Published

    2706 km cycling in 2 weeks: effects on cardiac function in 6 elderly male athletes

    Morville, T., Rosenkilde, M., Mattsson, N., Dela, Flemming, Helge, Jørn Wulff & Rasmusen, Hanne K., 2018, In: Physician and Sportsmedicine. 46, 3, p. 263-268 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    5'-AMP activated protein kinase is involved in the regulation of myocardial ß-oxidative capacity in mice

    Stride, N., Larsen, S., Treebak, Jonas Thue, Hansen, C. N., Hey-Mogensen, M., Speerschneider, T., Jensen, Thomas Elbenhardt, Jeppesen, J., Wojtaszewski, Jørgen F P, Richter, Erik A., Køber, Lars Valeur & Dela, Flemming, 22 Feb 2012, In: Frontiers in Physiology. 3, 7 p., 00033.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    In Vitro and In Vivo Detection of Mitophagy in Human Cells, C. Elegans, and Mice

    Fang, E. F., Palikaras, K., Sun, N., Fivenson, E. M., Spangler, R. D., Kerr, J. S., Cordonnier, S. A., Hou, Y., Dombi, E., Kassahun, H., Tavernarakis, N., Poulton, J., Nilsen, H. & Bohr, Vilhelm, 2017, In: Journal of Visualized Experiments. 129, e56301.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Rev1 deficiency induces a metabolic shift in MEFs that can be manipulated by the NAD+ precursor nicotinamide riboside

    Anugula, Sharath, Li, Zhiquan, Li, Yuan, Hendriksen, A., Christensen, P. B., Wang, L., Monk, J. M., de Wind, N., Bohr, Vilhelm, Desler, Claus, Naviaux, R. K. & Rasmussen, Lene Juel, 2023, In: Heliyon. 9, 6, e17392.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    A Biological Age Model Designed for Health Promotion Interventions: Protocol for an Interdisciplinary Study for Model Development

    Husted, Karina Louise Skov, Fogelstrom, M., Hulst, P., Brink-Kjaer, A., Henneberg, K., Sorensen, H. B. D., Dela, Flemming & Helge, Jørn Wulff, 2020, In: JMIR Research Protocols. 9, 10, 13 p., 19209.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    A Model for Estimating Biological Age From Physiological Biomarkers of Healthy Aging: Cross-sectional Study

    Husted, Karina Louise Skov, Brink-Kjaer, A., Fogelstrom, M., Hulst, P., Bleibach, A., Henneberg, K., Sorensen, H. B. D., Dela, Flemming, Jacobsen, Jens Christian Brings & Helge, Jørn Wulff, 2022, In: JMIR Aging. 5, 2, 15 p., 35696.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    A Small Molecule Inhibitor of the BLM Helicase Modulates Chromosome Stability in Human Cells

    Nguyen, G. H., Dexheimer, T. S., Rosenthal, A. S., Chu, W. K., Singh, D. K., Mosedale, G., Bachrati, C. Z., Schultz, L., Sakurai, M., Savitsky, P., Abu, M., McHugh, P. J., Bohr, Vilhelm, Harris, C. C., Jadhav, A., Gileadi, O., Maloney, D. J., Simeonov, A. & Hickson, Ian David, 24 Jan 2013, In: Chemistry & Biology. 20, 1, p. 55-62 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    A high carbohydrate diet remains the evidence based choice for elite athletes to optimise performance

    Helge, Jørn Wulff, 1 May 2017, In: Journal of Physiology. 595, 9, p. 2775-2775

    Research output: Contribution to journal › Comment/debate › Research › peer-review

  10. Published

    A high-fat diet and NAD+ activate sirt1 to rescue premature aging in cockayne syndrome

    Scheibye-Knudsen, M., Mitchell, S. J., Fang, E. F., Iyama, T., Ward, T., Wang, J., Dunn, C. A., Singh, N., Veith, S., Hasan-Olive, M. M., Mangerich, A., Wilson, M. A., Mattson, M. P., Bergersen, L. H., Cogger, V. C., Warren, A., Le Couteur, D. G., Moaddel, R., Wilson, D. M., Croteau, D. L. & 2 others, De Cabo, R. & Bohr, Vilhelm, 4 Nov 2014, In: Cell Metabolism. 20, 5, p. 840-855 16 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    A ketogenic diet accelerates neurodegeneration in mice with induced mitochondrial DNA toxicity in the forebrain

    Lauritzen, K. H., Hasan-Olive, M. M., Regnell, C. E., Kleppa, L., Scheibye-Knudsen, Morten, Gjedde, Albert, Klungland, A., Bohr, Vilhelm, Storm-Mathisen, J. & Bergersen, L. H., Dec 2016, In: Neurobiology of Aging. 48, p. 34-47

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    A maximal cycle test with good validity and high repeatability in adults of all ages

    Eriksen, L., Tolstrup, J. S., Larsen, Steen, Grønbæk, M. & Helge, Jørn Wulff, Dec 2014, In: International Journal of Sports Medicine. 35, 14, p. 1184-9 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    A novel method for determining human ex vivo submaximal skeletal muscle mitochondrial function

    Hey-Mogensen, M., Gram, M., Jensen, M. B., Lund, M. T., Hansen, C. N., Scheibye-Knudsen, Morten, Bohr, Vilhelm & Dela, Flemming, 1 Sep 2015, In: The Journal of Physiology. 593, 17, p. 3991-4010 20 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    A randomized double-blind study of testosterone replacement therapy or placebo in testicular cancer survivors with mild Leydig cell insufficiency (Einstein-intervention)

    Bandak, M., Jørgensen, N., Juul, Anders, Lauritsen, J., Kreiberg, M., Oturai, P. S., Helge, Jørn Wulff & Daugaard, G., 3 Jul 2017, In: B M C Cancer. 17, 8 p., 461.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    ADAMTS9 regulates skeletal muscle insulin sensitivity through extracellular matrix alterations

    Graae, A-S., Grarup, N., Ribel-Madsen, R., Lystbæk, S. H., Boesgaard, T., Staiger, H., Fritsche, A., Wellner, N., Sulek, K., Kjølby, M. F., Backe, M. B., Chubanava, S., Prats, C., Serup, A. K. L., Birk, J. B., Dubail, J., Gillberg, L., Vienberg, S. G., Nykjær, A., Kiens, B. & 10 others, Wojtaszewski, Jørgen F P, Larsen, Steen, Apte, S. S., Häring, H., Vaag, A., Zethelius, B., Pedersen, Oluf Borbye, Treebak, Jonas Thue, Hansen, Torben & Holst, Birgitte, 2019, In: Diabetes. 68, 3, p. 502-514

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Absent Exercise-Induced Improvements in Fat Oxidation in Women With Polycystic Ovary Syndrome After High-Intensity Interval Training

    Lionett, S., Kiel, I. A., Røsbjørgen, R., Lydersen, S., Larsen, Steen & Moholdt, T., 2021, In: Frontiers in Physiology. 12, 13 p., 649794.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Accelerated progression of white matter hyperintensities and subsequent risk of mortality: a 12-year follow-up study

    Sabayan, B., van der Grond, J., Westendorp, Rudi GJ, van Buchem, M. A. & de Craen, A. J. M., Jun 2015, In: Neurobiology of Aging. 36, 6, p. 2130–2135 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Accuracy of Continuous Glucose Monitoring Measurements in Normo-Glycemic Individuals

    Akintola, A. A., Noordam, R., Jansen, S. W., de Craen, A. J., Ballieux, B. E., Cobbaert, C. M., Mooijaart, S. P., Pijl, H., Westendorp, Rudi GJ & van Heemst, D., 7 Oct 2015, In: PloS one. 10, 10, p. 1-13 13 p., e0139973.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Accuracy of a Clinical Applicable Method for Prediction of VO2max Using Seismocardiography

    Hansen, Mikkel Thunestvedt, Husted, Karina Louise Skov, Fogelstrøm, M., Rømer, Tue, Schmidt, S. E., Sørensen, K. & Helge, Jørn Wulff, 2023, In: International Journal of Sports Medicine. 44, 9, p. 650-656

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Acetaminophen toxicity induces mitochondrial complex I inhibition in human liver tissue

    Chrøis, K. M., Larsen, Steen, Pedersen, J. S., Rygg, M. O., Boilsen, A. E. B., Bendtsen, Flemming & Dela, Flemming, 2020, In: Basic & Clinical Pharmacology & Toxicology. 126, 1, p. 86-91

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Acquired Localized Cutis Laxa due to Increased Elastin Turnover

    Nygaard, R. H., Maynard, S., Schjerling, P., Kjær, M., Qvortrup, Klaus, Bohr, Vilhelm, Rasmussen, Lene Juel, Jemec, Gregor & Heidenheim, M., 14 Jun 2016, In: Case Reports in Dermatology. 8, 1, p. 42-51 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Actovegin, a non-prohibited drug increases oxidative capacity in human skeletal muscle

    Søndergård, S. D., Dela, Flemming, Helge, Jørn Wulff & Larsen, Steen, Oct 2016, In: European Journal of Sport Science. 16, 7, p. 801-807 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Acute exercise improves motor memory: Exploring potential biomarkers

    Skriver, K. C., Roig, M., Lundbye-Jensen, Jesper, Pingel, Jessica, Helge, Jørn Wulff, Kiens, Bente & Nielsen, Jens Bo, 2014, In: Neurobiology of Learning and Memory. 116, p. 46-58 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Adipocyte size and cellular expression of caveolar proteins analyzed by confocal microscopy.

    Hulstrøm, V., Prats Gavalda, Clara & Vinten, J., 15 Jun 2013, In: American Journal of Physiology: Cell Physiology. 304, 12, p. C1168-75 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Adipose tissue mitochondrial respiration and lipolysis before and after a weight loss by diet and RYGB

    Hansen, M., Lund, M. T., Gregers, E., Kraunsøe, R., van Hall, Gerrit, Helge, Jørn Wulff & Dela, Flemming, Oct 2015, In: Obesity. 23, 10, p. 2022-2229 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    Adverse Metabolic Risk Profiles in Greenlandic Inuit Children Compared to Danish Children

    Munch-Andersen, T., Sorensen, K., Andersen, L. B., Aachmann-Andersen, N. J., Aksglaede, L., Juul, A. & Helge, Jørn Wulff, Jun 2013, In: Obesity. 21, 6, p. 1226-1231 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    Aerobic Exercise Performance and Muscle Strength in Statin Users-The LIFESTAT Study

    Morville, T., Dohlmann, T. L., Kuhlman, A. B., Sahl, Ronni Eg, Kriegbaum, Margit, Larsen, Steen, Dela, Flemming & Helge, Jørn Wulff, 2019, In: Medicine and Science in Sports and Exercise. 51, 7, p. 1429-1437 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    Aerobic Exercise Training Increases Muscle Water Content in Obese Middle-Age Men

    Mora-Rodríguez, R., Sanchez-Roncero, A., Fernández-Elías, V. E., Guadalupe-Grau, A., Ortega, J. F., Dela, Flemming & Helge, Jørn Wulff, May 2016, In: Medicine and Science in Sports and Exercise. 48, 5, p. 822-828 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    Aerobic and resistance exercise training reverses age-dependent decline in NAD(+) salvage capacity in human skeletal muscle

    de Guia, R. M., Agerholm, M., Nielsen, Thomas Svava, Consitt, L. A., Sogaard, D., Helge, Jørn Wulff, Larsen, Steen, Brandauer, J., Houmard, J. A. & Treebak, Jonas Thue, 2019, In: Physiological Reports. 7, 12, 15 p., e14139.

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    Age- and Functional Status-Dependent Association Between Blood Pressure and Cognition: The Milan Geriatrics 75+ Cohort Study

    Ogliari, G., Sabayan, B., Mari, D., Rossi, P. D., Lucchi, T. A., de Craen, A. J. M. & Westendorp, Rudi GJ, Sep 2015, In: Journal of the American Geriatrics Society. 63, 9, p. 1741-1748 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Published

    Age-related macular degeneration: A two-level model hypothesis

    Rozing, Maarten Pieter, Durhuus, J. A., Krogh Nielsen, M., Subhi, Y., Kirkwood, T. B. L., Westendorp, Rudi GJ & Sørensen, Torben Lykke, 2020, In: Progress in Retinal and Eye Research. 76, 100825.

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. Published

    Aging in high functioning elderly persons: study design and analyses of behavioral and psychological factors

    Finkenzeller, T., Poetzelsberger, B., Koesters, A., Wuerth, S., Amesberger, G., Dela, Flemming & Mueller, E., 2019, In: Scandinavian Journal of Medicine & Science in Sports. 29, p. 7-16

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. Published

    Aging, longevity and health

    Rasmussen, Lene Juel, Sander, M., Wewer, Ulla M. & Bohr, Vilhelm, 23 Jul 2011, In: Mechanisms of Ageing and Development. p. 522-32 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Published

    Akt and Rac1 signalling are jointly required for insulin-stimulated glucose uptake in skeletal muscle and downregulated in insulin resistance

    Sylow, Lykke, Kleinert, Maximilian, Pehmøller, C., Prats Gavalda, Clara, Chiu, T. T., Klip, A., Richter, Erik A. & Jensen, Thomas Elbenhardt, 2014, In: Cellular Signalling. 26, 2, p. 323-331 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. Published

    Alpine Skiing With total knee ArthroPlasty (ASWAP): metabolism, inflammation, and skeletal muscle fiber characteristics

    Kristensen, M., Pötzelsberger, B., Scheiber, P., Bergdahl, A., Hansen, C. N., Andersen, J. L., Narici, M., Salvioli, S., Conte, M., Müller, E. & Dela, Flemming, Aug 2015, In: Scandinavian Journal of Medicine & Science in Sports. 25, Supplement S2, p. 40-48 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    Alpine Skiing With total knee ArthroPlasty (ASWAP): study design and intervention

    Koesters, A., Poetzelsberger, B., Dela, Flemming, Dorn, U., Hofstaedter, T., Fink, C. & Mueller, E., Aug 2015, In: Scandinavian Journal of Medicine & Science in Sports. 25, Supplement S2, p. 3-9 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Published

    Alteration of mitochondrial homeostasis is an early event in a C. elegans model of human tauopathy

    Palikaras, K., Achanta, K., Choi, S., Akbari, M. & Bohr, Vilhelm, 2021, In: Aging. 13, 21, p. 23876-23894 19 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. Published

    Altered cardiovascular risk pattern of LDL cholesterol in older adults

    Rozing, Maarten Pieter & Westendorp, Rudi GJ, 2023, In: Current Opinion in Lipidology. 34, 1, p. 22-26 5 p.

    Research output: Contribution to journal › Review › Research › peer-review

  39. Published

    Altered mitochondrial regulation in quadriceps muscles of patients with COPD

    Naimi, A. I., Bourbeau, J., Perrault, H., Baril, J., Wright-Paradis, C., Rossi, A., Taivassalo, T., Sheel, A. W., Rabøl, R., Dela, Flemming & Boushel, R. C., 2011, In: Clinical Physiology and Functional Imaging. 31, 2, p. 124-31 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  40. Published

    An Emerging Epidemic of Noncommunicable Diseases in Developing Populations Due to a Triple Evolutionary Mismatch

    Koopman, J. J. E., van Bodegom, D., Ziem, J. B. & Westendorp, Rudi GJ, Jun 2016, In: American Journal of Tropical Medicine and Hygiene. 94, 6, p. 1189-1192 4 p.

    Research output: Contribution to journal › Comment/debate › Research › peer-review

  41. Published

    An Internet-Based Physical Activity Intervention to Improve Quality of Life of Inactive Older Adults: A Randomized Controlled Trial

    Broekhuizen, K., de Gelder, J., Wijsman, C. A., Wijsman, L. W., Westendorp, Rudi GJ, Verhagen, E., Slagboom, P. E., de Craen, A. J., van Mechelen, W., van Heemst, D., van der Ouderaa, F. & Mooijaart, S. P., Apr 2016, In: Journal of Medical Internet Research. 18, 4, p. 1-11 11 p., e74.

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. Published

    An analysis of the productivity and impact of clinical PhD theses from the University of Copenhagen

    Rømer, Tue, Hansen, Mikkel Thunestvedt & Helge, Jørn Wulff, 2020, In: Danish Medical Journal. 67, 5, A12190731.

    Research output: Contribution to journal › Journal article › Research › peer-review

  43. Published

    An in vivo study on brain microstructure in biological and chronological ageing

    Altmann-Schneider, I., de Craen, A. J. M., van den Berg-Huysmans, A. A., Slagboom, P., Westendorp, Rudi GJ, van Buchem, M. A. & van der Grond, J., 25 Mar 2015, In: PloS one. 10, 3, p. 1-12 12 p., e0120778.

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Published

    An individual participant data analysis of prospective cohort studies on the association between subclinical thyroid dysfunction and depressive symptoms

    Wildisen, L., Del Giovane, C., Moutzouri, E., Beglinger, S., Syrogiannouli, L., Collet, T-H., Cappola, A. R., Asvold, B. O., Bakker, S. J. L., Yeap, B. B., Almeida, O. P., Ceresini, G., Dullaart, R. P. F., Ferrucci, L., Grabe, H., Jukema, J. W., Nauck, M., Trompet, S., Voelzke, H., Westendorp, R. & 7 others, Gussekloo, J., Kloppel, S., Aujesky, D., Bauer, D., Peeters, R., Feller, M. & Rodondi, N., 2020, In: Scientific Reports. 10, 1, 12 p., 19111.

    Research output: Contribution to journal › Journal article › Research › peer-review

  45. Published

    An optimized histochemical method to assess skeletal muscle glycogen and lipid stores reveals two metabolically distinct populations of type I muscle fibers

    Prats Gavalda, Clara, Gomez-Cabello, A., Nordby, P., Andersen, J. L., Helge, Jørn Wulff, Dela, Flemming, Baba, O. & Ploug, Thorkil, 2013, In: PloS one. 8, 10, p. e77774 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  46. Published

    Angiotensin-Converting Enzyme 2 (SARS-CoV-2 receptor) expression in human skeletal muscle

    Perez-Valera, M., Martinez-Canton, M., Gallego-Selles, A., Galván-Alvarez, V., Gelabert-Rebato, M., Morales-Alamo, D., Santana, A., Martin-Rodriguez, S., Ponce-Gonzalez, J. G., Larsen, S., Losa-Reyna, J., Perez-Suarez, I., Dorado, C., Curtelin, D., Gonzalez-Henriquez, J. J., Boushel, R., Hallen, J., de Pablos Velasco, P., Freixinet-Gilart, J., Holmberg, H. C. & 3 others, Helge, Jørn Wulff, Martin-Rincon, M. & Calbet, J. A. L., 2021, In: Scandinavian Journal of Medicine and Science in Sports. 31, 12, p. 2249-2258 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. Published

    Angiotensin-converting enzyme activity and cognitive impairment during hypoglycaemia in healthy humans

    Pedersen-Bjergaard, Ulrik, Thomsen, Carsten Eckhart, Høgenhaven, H., Smed, A., Kjaer, T. W., Holst, Jens Juul, Dela, Flemming, Hilsted, Linda, Frandsen, E., Pramming, S. & Thorsteinsson, B., 2008, In: Journal of the Renin-Angiotensin-Aldosterone System. 9, 1, p. 37-48 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  48. Published

    Anthropometry, DXA and leptin reflect subcutaneous but not visceral abdominal adipose tissue by MRI in 197 healthy adolescents

    Tinggaard, J., Hagen, C. P., Christensen, A. N., Mouritsen, A., Mieritz, M. G., Wohlfahrt-Veje, C., Helge, Jørn Wulff, Beck, T. N., Fallentin, E., Larsen, R., Jensen, R. B., Juul, Anders & Main, Katharina Maria, 2017, In: Pediatric Research. 82, p. 620-628

    Research output: Contribution to journal › Journal article › Research › peer-review

  49. Published

    Antioxidant enzymes and Nrf2/Keap1 in human skeletal muscle: Influence of age, sex, adiposity and aerobic fitness

    Galvan-Alvarez, V., Gallego-Selles, A., Martinez-Canton, M., García-Gonzalez, E., Gelabert-Rebato, M., Ponce-Gonzalez, J. G., Larsen, Steen, Morales-Alamo, D., Losa-Reyna, J., Perez-Suarez, I., Dorado, C., Perez-Valera, M., Holmberg, H. C., Boushel, R., de Pablos Velasco, P., Helge, Jørn Wulff, Martin-Rincon, M. & Calbet, J. A. L., 2023, In: Free Radical Biology and Medicine. 209, p. 282-291 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  50. Published

    Aprataxin localizes to mitochondria and preserves mitochondrial function

    Sykora, P., Croteau, D. L., Bohr, Vilhelm & Wilson, D. M., 3 May 2011, In: Proceedings of the National Academy of Sciences USA (PNAS). 108, 18, p. 7437-42 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  51. Published

    Are skin senescence and immunosenescence linked within individuals?

    Waaijer, M. E. C., Goldeck, D., Gunn, D. A., van Heemst, D., Westendorp, Rudi GJ, Pawelec, G. & Maier, A. B., 2019, In: Aging Cell. 18, 4, 5 p., e12956.

    Research output: Contribution to journal › Journal article › Research › peer-review

  52. Published

    Are substrate use during exercise and mitochondrial respiratory capacity decreased in arm and leg muscle in type 2 diabetes?

    Larsen, Steen, Ara, I., Rabøl, R., Andersen, J. L., Boushel, R., Dela, Flemming & Helge, Jørn Wulff, 2009, In: Diabetologia. 52, 7, p. 1400-8 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  53. Published

    Arm and leg substrate utilization and muscle adaptation after prolonged low-intensity training

    Helge, Jørn Wulff, 1 Aug 2010, In: Acta Physiologica (Print). 199, 4, p. 519-28 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  54. Published

    Assessment of health status by molecular measures in adults ranging from middle-aged to old: Ready for clinical use?

    Waaijer, M. E. C., Westendorp, Rudi GJ, Goldeck, D., Gunn, D. A., Pawelec, G., Stijntjes, M., Slagboom, P. E. & Maier, A. B., Jan 2017, In: Experimental Gerontology. 87, Part B, p. 175–181 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  55. Published

    Assessment of maximal fat oxidation during exercise: A systematic review

    Amaro-Gahete, F. J., Sanchez-Delgado, G., Jurado-Fasoli, L., De-la-O, A., Castillo, M. J., Helge, Jørn Wulff & Ruiz, J. R., 2019, In: Scandinavian Journal of Medicine & Science in Sports. 29, 7, p. 910-921

    Research output: Contribution to journal › Review › Research › peer-review

  56. Published

    Association Between Levothyroxine Treatment and Thyroid-Related Symptoms Among Adults Aged 80 Years and Older With Subclinical Hypothyroidism

    Mooijaart, S. P., Du Puy, R. S., Stott, D. J., Kearney, P. M., Rodondi, N., Westendorp, R. G. J., den Elzen, W. P. J., Postmus, I., Poortvliet, R. K. E., van Heemst, D., van Munster, B. C., Peeters, R. P., Ford, I., Kean, S., Messow, C-M., Blum, M. R., Collet, T-H., Watt, T., Dekkers, O. M., Jukema, J. W. & 3 others, Smit, J. W. A., Langhorne, P. & Gussekloo, J., 2019, In: J A M A: The Journal of the American Medical Association. 322, 20, p. 1977-1986 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  57. Published

    Association analysis of insulin-like growth factor-1 axis parameters with survival and functional status in nonagenarians of the Leiden Longevity Study

    van der Spoel, E., Rozing, M. P., Houwing-Duistermaat, J. J., Slagboom, P. E., Beekman, M., de Craen, A. J. M., Westendorp, Rudi GJ & van Heemst, D., 12 Nov 2015, In: Aging. 7, 11, p. 956–963 8 p., PMC4694065.

    Research output: Contribution to journal › Journal article › Research › peer-review

  58. Published

    Association between plasma leptin and blood pressure in two population-based samples of children and adolescents

    Grøntved, A., Steene-Johannessen, J., Kynde, I., Franks, P. W., Helge, Jørn Wulff, Froberg, K., Anderssen, S. A. & Andersen, L. B., 2011, In: Journal of Hypertension. 29, 6, p. 1093-100 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  59. Published

    Associations between insulin action and integrity of brain microstructure differ with familial longevity and with age

    Akintola, A. A., van den Berg, A., van Buchem, M. A., Jansen, S. W., Slagboom, E. P., Westendorp, Rudi GJ, van der Grond, J. & van Heemst, D., 28 May 2015, In: Frontiers in Aging Neuroscience. 7, p. 1-9 9 p., 92.

    Research output: Contribution to journal › Journal article › Research › peer-review

  60. Published

    Associations between vitamin D status and atherosclerosis among Inuit in Greenland

    Gjødesen, C. U., Jørgensen, M. E., Bjerregaard, P., Dahl-Petersen, I. K., Larsen, C. V. L., Noël, M., Melbye, M., Cohen, A. S., Lundqvist, M., Hougaard, D. M., Helge, Jørn Wulff & Nielsen, N. O., Jan 2018, In: Atherosclerosis. 268, p. 145-151 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  61. Published

    Associations of Various Health-Ratings with Geriatric Giants, Mortality and Life Satisfaction in Older People

    Puvill, T., Lindenberg, J., Gussekloo, J., de Craen, A. J. M., Slaets, J. P. J. & Westendorp, Rudi GJ, 22 Sep 2016, In: P L o S One. 11, 9, p. 1-13 13 p., e0163499.

    Research output: Contribution to journal › Journal article › Research › peer-review

  62. Published

    Associations of subjective vitality with DNA damage, cardiovascular risk factors and physical performance

    Maynard, S., Keijzers, G., Hansen, Åse Marie, Osler, Merete, Molbo, Drude, Bendix, L., Møller, Peter, Loft, Steffen, Moreno-Villanueva, M., Bürkle, A., Hvitby, C. P., Schurman, S. H., Stevnsner, T. V., Rasmussen, Lene Juel, Avlund, K. & Bohr, Vilhelm, Jan 2015, In: Acta Physiologica (Print). 213, 1, p. 156-170 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  63. Published

    Atorvastatin impairs liver mitochondrial function in obese Göttingen Minipigs but heart and skeletal muscle are not affected

    Christiansen, L. B., Dohlmann, T. L., Ludvigsen, T. P., Parfieniuk, E., Ciborowski, M., Szczerbinski, L., Kretowski, A., Desler, Claus, Tiano, L., Orlando, P., Martinussen, Torben, Olsen, Lisbeth Høier & Larsen, Steen, 2021, In: Scientific Reports. 11, 15 p., 2167.

    Research output: Contribution to journal › Journal article › Research › peer-review

  64. Published

    Base excision repair activities differ in human lung cancer cells and corresponding normal controls

    Karahalil, B., Bohr, Vilhelm & De Souza-Pinto, N. C., 1 Dec 2010, In: Anticancer Research. 30, 12, p. 4963-71 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  65. Published

    Base excision repair causes age-dependent accumulation of single-stranded DNA breaks that contribute to Parkinson disease pathology

    SenGupta, T., Palikaras, K., Esbensen, Y. Q., Konstantinidis, G., Galindo, F. J. N., Achanta, K., Kassahun, H., Stavgiannoudaki, I., Bohr, Vilhelm, Akbari, M., Gaare, J., Tzoulis, C., Tavernarakis, N. & Nilsen, H., 2021, In: Cell Reports. 36, 10, 109668.

    Research output: Contribution to journal › Journal article › Research › peer-review

  66. Published

    Base excision repair of oxidative DNA damage and association with cancer and aging

    Maynard, S., Schurman, S. H., Harboe, C., de Souza-Pinto, N. C. & Bohr, Vilhelm, 1 Jan 2009, In: Carcinogenesis. 30, 1, p. 2-10 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  67. Published

    Bedside manners: How to deal with delirium

    Westendorp, Rudi GJ, Sep 2017, In: Cleveland Clinic Journal of Medicine. 84, 9, p. 699-700 2 p.

    Research output: Contribution to journal › Editorial › Research › peer-review

  68. Published

    Being Active, Engaged, and Healthy: Older Persons' Plans and Wishes to Age Successfully

    Huijg, J. M., van Delden, A. (. E. Q., van der Ouderaa, F. J. G., Westendorp, Rudi GJ, Slaets, J. P. J. & Lindenberg, J., 1 Mar 2017, In: Journals of Gerontology. Series B: Psychological Sciences & Social Sciences. 72, 2, p. 228-236 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  69. Published

    Beta-aminoisobutyric acid is released by contracting human skeletal muscle and lowers insulin release from INS-1 832/3 cells by mediating mitochondrial energy metabolism

    Barlow, J. P., Karstoft, K., Vigelsø, A., Gram, M., Helge, Jørn Wulff, Dela, Flemming, Pappan, K., O'Neil, D., Dunn, W. & Solomon, T. P. J., 2020, In: Metabolism open. 7, p. 100053

    Research output: Contribution to journal › Journal article › Research › peer-review

  70. Published

    Bi-directional routing of DNA mismatch repair protein human exonuclease 1 to replication foci and DNA double strand breaks

    Liberti, S. E., Andersen, S. D., Wang, J., May, A., Miron, S., Perderiset, M., Keijzers, G., Nielsen, Finn Cilius, Charbonnier, J., Bohr, Vilhelm & Rasmussen, Lene Juel, 2 Jan 2011, In: DNA Repair. 10, 1, p. 73-86 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  71. Published

    Blood pressure and 10-year mortality risk in the Milan Geriatrics 75+ Cohort Study: role of functional and cognitive status

    Ogliari, G., Westendorp, Rudi GJ, Muller, M., Mari, D., Torresani, E., Felicetta, I., Lucchi, T., Rossi, P. D., Sabayan, B. & de Craen, A. J. M., 2015, In: Age and Ageing. 44, 6, p. 932-937 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  72. Published

    Blood temperature and perfusion to exercising and non-exercising human limbs

    González-Alonso, J., Calbet, J. A. L., Boushel, R., Helge, Jørn Wulff, Søndergaard, H., Munch-Andersen, T., van Hall, Gerrit, Mortensen, S. P. & Secher, Niels H., 1 Oct 2015, In: Experimental Physiology. 100, 10, p. 1118-1131 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  73. Published

    Bohr på ny

    Bohr, Vilhelm, Bohr, T., Topsøe, H., Bruun, L., Knudsen, H., Nielsen, H., Aaserud, Finn, Grandin, K., von Bülow, H., Kragh, H., Andersen, Anja C., Mølmer, K., Favrholdt, D., Faye, J. & Zinkernagel, H., 2 May 2013, København: Forlaget Epsilon.Dk.

    Research output: Book/Report › Book › Communication

  74. Published

    Bone mineral density in lifelong trained male football players compared with young and elderly untrained men

    Hagman, M., Helge, Eva Wulff, Hornstrup, T., Fristrup, B., Nielsen, Jens Jung, Jørgensen, N. R., Andersen, J. L., Helge, Jørn Wulff & Krustrup, P., 2018, In: Journal of Sport and Health Science. 7, 2, p. 159-168 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  75. Published

    CDK2 phosphorylation of Werner protein (WRN) contributes to WRN’s DNA double-strand break repair pathway choice

    Lee, J. H., Shamanna, R. A., Kulikowicz, T., Fakouri, N. B., Kim, E. W., Christiansen, L. S., Croteau, D. L. & Bohr, Vilhelm, 2021, In: Aging Cell. 20, 11, 14 p., e13484.

    Research output: Contribution to journal › Journal article › Research › peer-review

  76. Published

    Calculating the Rate of Senescence From Mortality Data: An Analysis of Data From the ERA-EDTA Registry

    Koopman, J. J. E., Rozing, M. P., Kramer, A., Abad, J. M., Finne, P., Heaf, J. G., Hoitsma, A. J., De Meester, J. M. J., Palsson, R., Postorino, M., Ravani, P., Wanner, C., Jager, K. J., van Bodegom, D. & Westendorp, Rudi GJ, Apr 2016, In: Journals of Gerontology. Series A: Biological Sciences & Medical Sciences. 71, 4, p. 468-474 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  77. Published

    Cardiac and metabolic changes in long-term high fructose-fat fed rats with severe obesity and extensive intramyocardial lipid accumulation

    Axelsen, L. N., Lademann, J. B., Petersen, J. S., von Holstein-Rathlou, Niels-Henrik, Ploug, Thorkil, Prats Gavalda, Clara, Pedersen, H. D. & Kjølbye, A. L., 2010, In: American Journal of Physiology: Regulatory, Integrative and Comparative Physiology. 298, 6, p. R1560-70

    Research output: Contribution to journal › Journal article › Research › peer-review

  78. Published

    Cardiac, Skeletal, and smooth muscle mitochondrial respiration: Are all mitochondria created equal?

    Park, S., Gifford, J. R., Andtbacka, R. H. I., Hyngstrom, J. R., Garten, R. S., Diakos, N. A., Ives, S. J., Dela, Flemming, Larsen, Steen, Drakos, S. & Richardson, R. S., 6 Jun 2014, In: American Journal of Physiology: Heart and Circulatory Physiology. 307, 3, p. H346-52 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  79. Published

    Cardioprotective effect of succinate dehydrogenase inhibition in rat hearts and human myocardium with and without diabetes mellitus

    Jespersen, N. R., Hjortbak, M. V., Lassen, T. R., Støttrup, N. B., Johnsen, J., Tonnesen, P. T., Larsen, Steen, Kimose, H. H. & Bøtker, H. E., 2020, In: Scientific Reports. 10, 1, 15 p., 10344.

    Research output: Contribution to journal › Journal article › Research › peer-review

  80. Published

    Cardiorespiratory fitness in 16 025 adults aged 18-91 years and associations with physical activity and sitting time

    Eriksen, L., Grønbæk, M., Helge, Jørn Wulff & Tolstrup, J. S., Dec 2016, In: Scandinavian Journal of Medicine & Science in Sports. 26, 12, p. 1435-1443 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  81. Published

    Cardiovascular and metabolic health effects of team handball training in overweight women: Impact of prior experience

    Hornstrup, T., Póvoas, S., Helge, Jørn Wulff, Melcher, Pia Grethe Sandfeld, Fristrup, B., Andersen, J. L., Møgelvang, R., Hansen, Peter Riis, Nybo, Lars & Krustrup, P., 2020, In: Scandinavian Journal of Medicine & Science in Sports. 30, 2, p. 281-294 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  82. Published

    Cardiovascular disease markers in type 2 diabetes: the effects of a moderate home-based exercise training programme

    Scheede-Bergdahl, C., Benee Olsen, D., Reving, D., Boushel, R. & Dela, Flemming, 2009, In: Diabetes and Vascular Disease Research. 6, 4, p. 291-6 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  83. Published

    Cardiovascular, muscular, and skeletal adaptations to recreational team handball training: a randomized controlled trial with young adult untrained men

    Hornstrup, T., Løwenstein, F. T., Larsen, M. A., Helge, Eva Wulff, Póvoas, S., Helge, Jørn Wulff, Nielsen, Jens Jung, Fristrup, B., Andersen, J. L., Gliemann, Lasse, Nybo, Lars & Krustrup, P., 2019, In: European Journal of Applied Physiology. 119, 2, p. 561-573 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  84. Published

    Cellular senescence and chronological age in various human tissues: A systematic review and meta-analysis

    Tuttle, C. S. L., Waaijer, M. E. C., Slee-Valentijn, M. S., Stijnen, T., Westendorp, Rudi GJ & Maier, A. B., 2020, In: Aging Cell. 19, 2, 11 p., e13083.

    Research output: Contribution to journal › Review › Research › peer-review

  85. Published

    Center for Sund Aldring: Regeringen overser ældres ret til selvbestemmelse

    Clotworthy, Amy & Westendorp, Rudi GJ, 19 May 2020, In: Altinget.dk. 1 p.

    Research output: Contribution to journal › Contribution to newspaper - Newspaper article › Communication

  86. Published

    Central and peripheral hemodynamics in exercising humans: leg vs arm exercise

    Calbet, J. A. L., González-Alonso, J., Helge, Jørn Wulff, Søndergaard, H., Munch-Andersen, T., Saltin, B. & Boushel, R., 2015, In: Scandinavian Journal of Medicine & Science in Sports. 25, Suppl 4, p. 144-157

    Research output: Contribution to journal › Journal article › Research › peer-review

  87. Published

    Cerebral autoregulation dynamics in endurance-trained individuals

    Lind-Holst, M., Cotter, J. D., Helge, Jørn Wulff, Boushel, R. C., Augustesen, H., Van Lieshout, J. J. & Pott, Frank Christian, 2011, In: Journal of Applied Physiology. 110, 5, p. 1327-33 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  88. Published

    Characterization of the Hypothalamic-Pituitary-Adrenal-Axis in Familial Longevity under Resting Conditions

    Jansen, S. W., Roelfsema, F., Akintola, A. A., Oei, N. Y., Cobbaert, C. M., Ballieux, B. E., van der Grond, J., Westendorp, Rudi GJ, Pijl, H. & van Heemst, D., 20 Jul 2015, In: PLOS ONE. 10, 7, p. 1-15 15 p., e0133119.

    Research output: Contribution to journal › Journal article › Research › peer-review

  89. Published

    Childhood hypo-adiponectinaemia but not hyper-leptinaemia is associated with insulin insensitivity 6 years later

    Kynde, I., Heitmann, B. L., Bygbjerg, Ib Christian, Andersen, L. B. & Helge, Jørn Wulff, May 2010, In: Pediatric Diabetes. 11, 3, p. 195-202 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  90. Published

    Circulating Thyroid Hormone Profile in Response to a Triiodothyronine Challenge in Familial Longevity

    Zutinic, A., Blauw, G. J., Pijl, H., Ballieux, B. E., Westendorp, Rudi GJ, Roelfsema, F. & van Heemst, D., 2020, In: Endocrine Research. 4, 10, 9 p., bvaa117.

    Research output: Contribution to journal › Journal article › Research › peer-review

  91. Published

    Clusters of Glycemic Response to Oral Glucose Tolerance Tests Explain Multivariate Metabolic and Anthropometric Outcomes of Bariatric Surgery in Obese Patients

    Szczerbinski, L., Taylor, M. A., Citko, A., Gorska, M., Larsen, Steen, Hady, H. R. & Kretowski, A., 2019, In: Journal of Clinical Medicine. 8, 8, 16 p., 1091.

    Research output: Contribution to journal › Journal article › Research › peer-review

  92. Published

    Cockayne Syndrome group B protein stimulates NEIL2 DNA glycosylase activity

    Aamann, M. D., Hvitby, C. P., Popuri, V., Muftuoglu, M., Lemminger, L. P. B., Skeby, C. K., Keijzers, G., Ahn, B., Bjørås, M., Bohr, Vilhelm & Stevnsner, T. V., Jan 2014, In: Mechanisms of Ageing and Development. 135, p. 1-14 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  93. Published

    Cockayne syndrome: Clinical features, model systems and pathways

    Karikkineth, A. C., Scheibye-Knudsen, Morten, Fivenson, E., Croteau, D. L. & Bohr, Vilhelm, 2017, In: Ageing Research Reviews. 33, p. 3-17

    Research output: Contribution to journal › Review › Research › peer-review

  94. Published

    Cockayne syndrome group A and B proteins converge on transcription-linked resolution of non-B DNA

    Scheibye-Knudsen, M., Tseng, A., Jensen, M. B., Scheibye-Alsing, K., Fang, E. F., Iyama, T., Bharti, S. K., Marosi, K., Froetscher, L., Kassahun, H., Eckley, D. M., Maul, R. W., Bastian, P., De, S., Ghosh, S., Nilsen, H., Goldberg, I. G., Mattson, M. P., Wilson, D. M. . III., Brosh, R. M. . J. & 2 others, Gorospe, M. & Bohr, Vilhelm, 1 Nov 2016, In: National Academy of Sciences. Proceedings. 113, 44, p. 12502-12507

    Research output: Contribution to journal › Journal article › Research › peer-review

  95. Published

    Cockayne syndrome group A and B proteins function in rRNA transcription through nucleolin regulation

    Okur, M. N., Lee, J., Osmani, W., Kimura, R., Demarest, T. G., Croteau, D. L. & Bohr, Vilhelm, 18 Mar 2020, In: Nucleic Acids Research. 48, 5, p. 2473-2485 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  96. Published

    Cockayne syndrome group B deficiency reduces H3K9me3 chromatin remodeler SETDB1 and exacerbates cellular aging

    Lee, J., Demarest, T. G., Babbar, M., Kim, E. W., Okur, M. N., De, S., Croteau, D. L. & Bohr, Vilhelm, 2019, In: Nucleic Acids Research. 47, 16, p. 8548-8562

    Research output: Contribution to journal › Journal article › Research › peer-review

  97. Published

    Cockayne syndrome group B protein prevents the accumulation of damaged mitochondria by promoting mitochondrial autophagy

    Scheibye-Knudsen, M., Ramamoorthy, M., Sykora, P., Maynard, S., Lin, P., Minor, R. K., Wilson, D. M., Cooper, M., Spencer, R., de Cabo, R., Croteau, D. L. & Bohr, Vilhelm, Apr 2012, In: The Journal of Experimental Medicine. 209, 4, p. 855-69 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  98. Published

    Cockayne syndrome group B protein promotes mitochondrial DNA stability by supporting the DNA repair association with the mitochondrial membrane

    Aamann, M. D., Sorensen, M. M., Hvitby, C. P., Berquist, B. R., Muftuoglu, M., Tian, J., de Souza-Pinto, N. C., Scheibye-Knudsen, M., Wilson, D. M., Stevnsner, T. V. & Bohr, Vilhelm, 1 Jul 2010, In: The FASEB Journal. 24, 7, p. 2334-46 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  99. Published

    Cockayne syndrome group B protein stimulates repair of formamidopyrimidines by NEIL1 DNA glycosylase

    Muftuoglu, M., de Souza-Pinto, N. C., Dogan, A., Aamann, M., Stevnsner, T., Rybanska, I., Kirkali, G., Dizdaroglu, M. & Bohr, Vilhelm, Apr 2009, In: Journal of Biological Chemistry. 284, 14, p. 9270-9 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  100. Published

    Cockayne syndrome proteins CSA and CSB maintain mitochondrial homeostasis through NAD+ signaling

    Okur, M. N., Fang, E. F., Fivenson, E. M., Tiwari, V., Croteau, D. L. & Bohr, Vilhelm, Dec 2020, In: Aging Cell. 19, 12, p. e13268

    Research output: Contribution to journal › Journal article › Research › peer-review

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