- 2023
- Published
Rev1 deficiency induces a metabolic shift in MEFs that can be manipulated by the NAD+ precursor nicotinamide riboside
Anugula, Sharath, Li, Zhiquan, Li, Yuan, Hendriksen, A., Christensen, P. B., Wang, L., Monk, J. M., de Wind, N., Bohr, Vilhelm, Desler, Claus, Naviaux, R. K. & Rasmussen, Lene Juel, 2023, In: Heliyon. 9, 6, e17392.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Accuracy of a Clinical Applicable Method for Prediction of VO2max Using Seismocardiography
Hansen, Mikkel Thunestvedt, Husted, Karina Louise Skov, Fogelstrøm, M., Rømer, Tue, Schmidt, S. E., Sørensen, K. & Helge, Jørn Wulff, 2023, In: International Journal of Sports Medicine. 44, 9, p. 650-656Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Altered cardiovascular risk pattern of LDL cholesterol in older adults
Rozing, Maarten Pieter & Westendorp, Rudi GJ, 2023, In: Current Opinion in Lipidology. 34, 1, p. 22-26 5 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Antioxidant enzymes and Nrf2/Keap1 in human skeletal muscle: Influence of age, sex, adiposity and aerobic fitness
Galvan-Alvarez, V., Gallego-Selles, A., Martinez-Canton, M., García-Gonzalez, E., Gelabert-Rebato, M., Ponce-Gonzalez, J. G., Larsen, Steen, Morales-Alamo, D., Losa-Reyna, J., Perez-Suarez, I., Dorado, C., Perez-Valera, M., Holmberg, H. C., Boushel, R., de Pablos Velasco, P., Helge, Jørn Wulff, Martin-Rincon, M. & Calbet, J. A. L., 2023, In: Free Radical Biology and Medicine. 209, p. 282-291 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cross-species comparison of pregnancy-induced GDF15
Klein, A. B., Ranea-Robles, Pablo, Nicolaisen, T. S., Gil, Cláudia, Johann, K., Prats Quesada, Júlia, Pistoljevic, N., Hviid, K. V. R., Olsen, L. F., Offersen, Simone Margaard, Helge, Jørn Wulff, Nielsen, Henriette Svarre, Bakker, J., Kleinert, Maximilian & Clemmensen, Christoffer, 2023, In: American Journal of Physiology - Endocrinology and Metabolism. 325, 4, p. E303-E309Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Danish Pathology Life Course (PATHOLIFE) cohort: a register based cohort extending upon a national tissue biobank
Yde, Pernille, Bartholdy, Andreas, Gjerdrum, Lise Mette Rahbek, Westendorp, Rudi GJ, Mortensen, Laust Hvas, Bhatt, Samir & Jensen, Majken Karoline, 2023, In: BMJ Open. 13, 4, 10 p., e068483.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Impact of Aging and Lifelong Exercise Training on Mitochondrial Function and Network Connectivity in Human Skeletal Muscle
Jørgensen, Stine Ringholm, Gudiksen, Anders, Halling, Jens Frey, Qoqaj, A., Rasmussen, P. M., Prats Gavalda, Clara, Plomgaard, Peter Stendahl & Pilegaard, Henriette, 2023, In: Journals of Gerontology. Series A: Biological Sciences & Medical Sciences. 78, 3, 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Long-term exposure to air pollution and risk of SARS-CoV-2 infection and COVID-19 hospitalization or death: Danish nationwide cohort study
Zhang, Jiawei, Lim, Youn-Hee, So, Rina, Jørgensen, J. T., Mortensen, Laust Hvas, Napolitano, George, Cole-Hunter, Thomas, Loft, Steffen, Bhatt, Samir, Hoek, G., Brunekreef, B., Westendorp, Rudi GJ, Ketzel, M., Brandt, J., Lange, Theis, Kølsen-Fisher, T. & Andersen, Zorana Jovanovic, 2023, In: The European respiratory journal. 61, 6, 50 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Long-term exposure to elemental components of fine particulate matter and all-natural and cause-specific mortality in a Danish nationwide administrative cohort study
So, R., Chen, J., Stafoggia, M., de Hoogh, K., Katsouyanni, K., Vienneau, D., Samoli, E., Rodopoulou, S., Loft, S., Lim, Y-H., Westendorp, R. G. J., Amini, H., Cole-Hunter, T., Bergmann, M., Shahri, S. M. T., Zhang, J., Maric, M., Mortensen, L. H., Bauwelinck, M., Klompmaker, J. O. & 9 others, , 2023, In: Environmental Research. 224, 11 p., 115552.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Predicting mortality and visualizing health care spending by predicted mortality in Danes over age 65
Hansen, A. V., Mortensen, Laust Hvas, Ekstrøm, Claus Thorn, Trompet, S. & Westendorp, Rudi GJ, 2023, In: Scientific Reports. 13, 1, 7 p., 1203.Research output: Contribution to journal › Journal article › Research › peer-review
- 2022
- Published
A Model for Estimating Biological Age From Physiological Biomarkers of Healthy Aging: Cross-sectional Study
Husted, Karina Louise Skov, Brink-Kjaer, A., Fogelstrom, M., Hulst, P., Bleibach, A., Henneberg, K., Sorensen, H. B. D., Dela, Flemming, Jacobsen, Jens Christian Brings & Helge, Jørn Wulff, 2022, In: JMIR Aging. 5, 2, 15 p., 35696.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Foreword
Bohr, Vilhelm, 2022, Molecular, Cellular, and Metabolic Fundamentals of Human Aging. Academic Press, p. xi-xiResearch output: Chapter in Book/Report/Conference proceeding › Preface/postscript › Research
- Published
Incorporating Baseline Outcome Data in Individual Participant Data Meta-Analysis of Non-randomized Studies
Syrogiannouli, L., Wildisen, L., Meuwese, C., Bauer, D. C., Cappola, A. R., Gussekloo, J., den Elzen, W. P. J., Trompet, S., Westendorp, R. G. J., Jukema, J. W., Ferrucci, L., Ceresini, G., Åsvold, B. O., Chaker, L., Peeters, R. P., Imaizumi, M., Ohishi, W., Vaes, B., Völzke, H., Sgarbi, J. A. & 7 others, , 2022, In: Frontiers in Psychiatry. 13, 774251.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Intravenous nicotinamide riboside elevates mouse skeletal muscle NAD+ without impacting respiratory capacity or insulin sensitivity
Damgaard, Mads Vargas, Nielsen, Thomas Svava, Basse, A. L., Chubanava, Sabina, Trost, K., Moritz, Thomas, Dellinger, R. W., Larsen, Steen & Treebak, Jonas Thue, 2022, In: iScience. 25, 2, 21 p., 103863.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Lamin A/C impairments cause mitochondrial dysfunction by attenuating PGC1 and the NAMPT-NAD+ pathway
Maynard, S., Hall, A., Galanos, P., Rizza, S., Yamamoto, T., Gram, H. H., Munk, S. H. N., Shoaib, Muhammad, Sørensen, Claus Storgaard, Bohr, Vilhelm, Lerdrup, Mads, Maya-Mendoza, A. & Bartek, J., 2022, In: Nucleic Acids Research. 50, 17, p. 9948-9965 18 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Meeting Report: Aging Research and Drug Discovery
Meron, E., Thaysen, M., Angeli, S., Antebi, A., Barzilai, N., Baur, J. A., Bekker-Jensen, S., Birkisdottir, M., Bischof, E., Bruening, J., Brunet, A., Buchwalter, A., Cabreiro, F., Cai, S., Chen, B. H., Ermolaeva, M., Ewald, C. Y., Ferrucci, L., Florian, M. C., Fortney, K. & 58 others, , 2022, In: Aging. 14, 2, p. 530-543 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
New hallmarks of ageing: a 2022 Copenhagen ageing meeting summary
Schmauck-Medina, T., Molière, A., Lautrup, S., Zhang, J., Chlopicki, S., Madsen, H. B., Cao, S., Soendenbroe, C., Mansell, E., Vestergaard, M. B., Li, Z., Shiloh, Y., Opresko, P. L., Egly, J. M., Kirkwood, T., Verdin, E., Bohr, V. A., Cox, L. S., Stevnsner, T., Rasmussen, L. J. & 1 others, , 2022, In: Aging. 14, 16, p. 6829-6839 11 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Subclinical thyroid dysfunction and incident diabetes: a systematic review and an individual participant data analysis of prospective cohort studies
Alwan, H., Villoz, F., Feller, M., Dullaart, R. P. F., Bakker, S. J. L., Peeters, R. P., Kavousi, M., Bauer, D. C., Cappola, A. R., Yeap, B. B., Walsh, J. P., Brown, S. J., Ceresini, G., Ferrucci, L., Gussekloo, J., Trompet, S., Iacoviello, M., Moon, J. H., Razvi, S., Bensenor, I. M. & 11 others, , 2022, In: European Journal of Endocrinology. 187, 5, p. S35-S46 12 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
The effect of 8 weeks of physical training on muscle performance and maximal fat oxidation rates in patients treated with simvastatin and coenzyme Q10 supplementation
Kuhlman, A. B., Mikkelsen, L. B., Regnersgaard, S., Heinrichsen, S., Nielsen, F. H., Frandsen, J., Orlando, P., Silvestri, S., Larsen, Steen, Helge, Jørn Wulff & Dela, Flemming, 2022, In: Journal of Physiology. 600, 3, p. 569-581 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Thyroid antibodies and levothyroxine effects in subclinical hypothyroidism: A pooled analysis of two randomized controlled trials
Lyko, C., Blum, M. R., Abolhassani, N., Stuber, M. J., Del Giovane, C., Feller, M., Moutzouri, E., Oberle, J., Jungo, K. T., Collet, T-H., den Elzen, W. P. J., Poortvliet, R. K. E., Du Puy, R. S., Dekkers, O. M., Trompet, S., Jukema, J. W., Aujesky, D., Quinn, T., Westendorp, R., Kearney, P. M. & 5 others, , 2022, In: Journal of Internal Medicine. 292, 6, p. 892-903 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Use of candles and risk of cardiovascular and respiratory events in a Danish cohort study
Loft, Steffen, Andersen, Zorana Jovanovic, Jorgensen, J. T., Kristiansen, A. D., Dam, J. K., Cramer, J., Westendorp, Rudi GJ, Lund, Rikke & Lim, Youn-Hee, 2022, In: Indoor Air. 32, 8, 10 p., 13086.Research output: Contribution to journal › Journal article › Research › peer-review
- 2021
- Published
Reablement through time and space: A scoping review of how the concept of ‘reablement’ for older people has been defined and operationalised
Clotworthy, Amy, Kusumastuti, S. & Westendorp, Rudi GJ, 15 Jan 2021, In: BMC Geriatrics. 21, 16 p., 61.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Absent Exercise-Induced Improvements in Fat Oxidation in Women With Polycystic Ovary Syndrome After High-Intensity Interval Training
Lionett, S., Kiel, I. A., Røsbjørgen, R., Lydersen, S., Larsen, Steen & Moholdt, T., 2021, In: Frontiers in Physiology. 12, 13 p., 649794.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Alteration of mitochondrial homeostasis is an early event in a C. elegans model of human tauopathy
Palikaras, K., Achanta, K., Choi, S., Akbari, M. & Bohr, Vilhelm, 2021, In: Aging. 13, 21, p. 23876-23894 19 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Angiotensin-Converting Enzyme 2 (SARS-CoV-2 receptor) expression in human skeletal muscle
Perez-Valera, M., Martinez-Canton, M., Gallego-Selles, A., Galván-Alvarez, V., Gelabert-Rebato, M., Morales-Alamo, D., Santana, A., Martin-Rodriguez, S., Ponce-Gonzalez, J. G., Larsen, S., Losa-Reyna, J., Perez-Suarez, I., Dorado, C., Curtelin, D., Gonzalez-Henriquez, J. J., Boushel, R., Hallen, J., de Pablos Velasco, P., Freixinet-Gilart, J., Holmberg, H. C. & 3 others, , 2021, In: Scandinavian Journal of Medicine and Science in Sports. 31, 12, p. 2249-2258 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Atorvastatin impairs liver mitochondrial function in obese Göttingen Minipigs but heart and skeletal muscle are not affected
Christiansen, L. B., Dohlmann, T. L., Ludvigsen, T. P., Parfieniuk, E., Ciborowski, M., Szczerbinski, L., Kretowski, A., Desler, Claus, Tiano, L., Orlando, P., Martinussen, Torben, Olsen, Lisbeth Høier & Larsen, Steen, 2021, In: Scientific Reports. 11, 15 p., 2167.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Base excision repair causes age-dependent accumulation of single-stranded DNA breaks that contribute to Parkinson disease pathology
SenGupta, T., Palikaras, K., Esbensen, Y. Q., Konstantinidis, G., Galindo, F. J. N., Achanta, K., Kassahun, H., Stavgiannoudaki, I., Bohr, Vilhelm, Akbari, M., Gaare, J., Tzoulis, C., Tavernarakis, N. & Nilsen, H., 2021, In: Cell Reports. 36, 10, 109668.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
CDK2 phosphorylation of Werner protein (WRN) contributes to WRN’s DNA double-strand break repair pathway choice
Lee, J. H., Shamanna, R. A., Kulikowicz, T., Fakouri, N. B., Kim, E. W., Christiansen, L. S., Croteau, D. L. & Bohr, Vilhelm, 2021, In: Aging Cell. 20, 11, 14 p., e13484.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cytosolic self-DNA—A potential source of chronic inflammation in aging
Akbari, M., Shanley, D. P., Bohr, Vilhelm & Rasmussen, Lene Juel, 2021, In: Cells. 10, 12, 3544.Research output: Contribution to journal › Review › Research › peer-review
- Published
Depleted myocardial coenzyme Q10 in cavalier king charles spaniels with congestive heart failure due to myxomatous mitral valve disease
Christiansen, L. B., Reimann, Maria Josefine, Schou-Pedersen, A. M. V., Larsen, Steen, Lykkesfeldt, Jens & Olsen, Lisbeth Høier, 2021, In: Antioxidants. 10, 2, p. 1-13 13 p., 161.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
EX-vivo whole blood stimulation with A2E does not elicit an inflammatory cytokine response in patients with age-related macular degeneration
Durhuus, J. A., Rozing, Maarten Pieter, Nielsen, M. K., Molbech, C. R., Keijzers, G., Scheibye-Knudsen, Morten, Rasmussen, Lene Juel, Westendorp, Rudi GJ & Sørensen, Torben Lykke, 2021, In: Scientific Reports. 11, 1, 8226.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effect of Levothyroxine Therapy on the Development of Depressive Symptoms in Older Adults With Subclinical Hypothyroidism An Ancillary Study of a Randomized Clinical Trial
Wildisen, L., Feller, M., Del Giovane, C., Moutzouri, E., Du Puy, R. S., Mooijaart, S. P., Collet, T., Poortvliet, R. K. E., Kearney, P., Quinn, T. J., Kloppel, S., Bauer, D. C., Peeters, R. P., Westendorp, Rudi GJ, Aujesky, D., Gussekloo, J. & Rodondi, N., 2021, In: JAMA network open. 4, 2, 12 p., 2036645.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effects of football fitness training on lymphedema and upper-extremity function in women after treatment for breast cancer: A randomized trial
Bloomquist, K., Krustrup, P., Fristrup, B., Sørensen, V., Helge, Jørn Wulff, Helge, Eva Wulff, Soelberg Vadstrup, E., Rørth, M., Hayes, S. C. & Uth, J., 2021, In: Acta Oncologica. 60, 3, p. 392-400 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Endotrophin is associated with chronic multimorbidity and all-cause mortality in a cohort of elderly women
Staunstrup, L. M., Bager, C. L., Frederiksen, P., Helge, Jørn Wulff, Brunak, Søren, Christiansen, C. & Karsdal, M., 2021, In: EBioMedicine. 68, 10 p., 103391.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Familial longevity is associated with lower baseline bone turnover but not differences in bone turnover in response to rhTSH
Zutinic, A., Roelfsema, F., Pijl, H., Ballieux, B. E., Westendorp, Rudi GJ, Blauw, G. J. & van Heemst, D., 2021, In: Aging. 13, 17, p. 21029-21039 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
High bone mineral density in lifelong trained female team handball players and young elite football players
Hagman, M., Helge, Eva Wulff, Fristrup, B., Jørgensen, Niklas Rye, Helge, Jørn Wulff & Krustrup, P., 2021, In: European Journal of Applied Physiology. 121, 10, p. 2825-2836 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Maximal fat oxidation rate is higher in fit women and unfit women with obesity, compared to normal weight unfit women
Frandsen, J., Hansen, I. M. D., Wismann, J. F., Olsen, M. H., Brage-Andersen, M. R., Sahl, Ronni Eg, Hansen, M., Ingersen, Arthur, Modvig, J. L., Schmücker, M., brl298, brl298, Dela, Flemming, Larsen, Steen & Helge, Jørn Wulff, 2021, In: Journal of Clinical Endocrinology and Metabolism. 106, 11, p. E4389-E4399 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Metabolomic Profile of Skeletal Muscle and Its Change Under a Mixed-Mode Exercise Intervention in Progressively Dysglycemic Subjects
Szczerbinski, L., Golonko, A., Taylor, M., Puchta, U., Konopka, P., Paszko, A., Citko, A., Szczerbinski, K., Gorska, M., Zabielski, P., Błachnio-Zabielska, A., Larsen, Steen & Kretowski, A., 2021, In: Frontiers in Endocrinology. 12, 13 p., 778442.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
NAD+ supplementation reduces neuroinflammation and cell senescence in a transgenic mouse model of Alzheimer's disease via cGAS-STING
Hou, Y., Wei, Y., Lautrup, S., Yang, B., Wang, Y., Cordonnier, S., Mattson, M. P., Croteau, D. L. & Bohr, Vilhelm, 2021, In: Proceedings of the National Academy of Sciences of the United States of America. 118, 37, e2011226118.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Olfactory dysfunction in aging and neurodegenerative diseases
Dan, X., Wechter, N., Gray, S., Mohanty, J. G., Croteau, D. L. & Bohr, Vilhelm, 2021, In: Ageing Research Reviews. 70, 101416.Research output: Contribution to journal › Review › Research › peer-review
- Published
One year of Football Fitness improves L1-L4 BMD, postural balance and muscle strength in women treated for breast cancer
Uth, J., Fristrup, B., Sørensen, V., Helge, Eva Wulff, Christensen, M. K., Kjærgaard, J. B., Møller, T. K., Helge, Jørn Wulff, Jørgensen, Niklas Rye, Rørth, M., Vadstrup, E. S. & Krustrup, P., 2021, In: Scandinavian Journal of Medicine & Science in Sports. 31, 7, p. 1545-1557 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Peak fat oxidation rate is closely associated with plasma free fatty acid concentrations in women; similar to men
Frandsen, J., Poggi, A. I., Ritz, C., Larsen, S., Dela, Flemming & Helge, Jørn Wulff, 2021, In: Frontiers in Physiology. 12, 11 p., 696261.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Pharmacological but not physiological GDF15 suppresses feeding and the motivation to exercise
Klein, A. B., Nicolaisen, T. S., Ørtenblad, N., Gejl, K. D., Jensen, R., Fritzen, A. M., Larsen, E. L., Karstoft, K., Poulsen, H. E., Morville, T., Sahl, R. E., Helge, J. W., Lund, J., Falk, S., Lyngbæk, M., Ellingsgaard, H., Pedersen, B. K., Lu, W., Finan, B., Jørgensen, S. B. & 5 others, , 2021, In: Nature Communications. 12, 9 p., 1041.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Reliability and variation in mitochondrial respiration in human adipose tissue
Sahl, Ronni Eg, Høy Helms, E. F., Schmücker, Malte, Flensted-Jensen, Mathias, Ingersen, Arthur, Morville, T., Dela, Flemming, Helge, Jørn Wulff & Larsen, S., 2021, In: Adipocytes. 10, 1, p. 605-611 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Six weeks of high intensity cycle training reduces H2O2 emission and increases antioxidant protein levels in obese adults with risk factors for type 2 diabetes
Flensted-Jensen, Mathias, Gram, M., Dela, Flemming, Helge, Jørn Wulff & Larsen, Steen, 2021, In: Free Radical Biology & Medicine. 173, p. 1-6Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The effects of 3 weeks of oral glutathione supplementation on whole body insulin sensitivity in obese males with and without type 2 diabetes: a randomized trial
Søndergård, S. D., Cintin, I., Kuhlman, A. B., Morville, T. H., Bergmann, M. L., Kjær, L. K., Poulsen, Henrik Enghusen, Giustarini, D., Rossi, R., Dela, Flemming, Helge, Jørn Wulff & Larsen, S., 2021, In: Applied Physiology, Nutrition and Metabolism. 46, 9, 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The influence of age, sex and cardiorespiratory fitness on maximal fat oxidation rate
Frandsen, J., Amaro-Gahete, F. J., Landgrebe, A., Dela, Flemming, Ruiz, J. R., Helge, Jørn Wulff & Larsen, Steen, 2021, In: Applied Physiology, Nutrition and Metabolism. 46, 10, p. 1241-1247Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The response of mitochondrial respiration and quantity in skeletal muscle and adipose tissue to exercise in humans with prediabetes
Szczerbinski, L., Taylor, M. A., Puchta, U., Konopka, P., Paszko, A., Citko, A., Szczerbinski, K., Goscik, J., Gorska, M., Larsen, Steen & Kretowski, A., 2021, In: Cells. 10, 11, 3013.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The training induced increase in whole-body peak fat oxidation rate may be attenuated with aging
Frandsen, J., Beck, T., Langkilde, C. H., Larsen, Steen, Dela, Flemming & Helge, Jørn Wulff, 2021, In: European Journal of Sport Science. 21, 1, p. 69-76Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Tipping Points-Do the Prognostic Values of Multimorbidity and Functional Status Vary with Age?
Thygesen, L. C., Christensen, K., Rorth, M., Sørensen, H. T., Vandenbroucke, J. P. & Westendorp, Rudi GJ, 2021, In: Clinical Epidemiology. 13, p. 853-857 5 p.Research output: Contribution to journal › Editorial › Research › peer-review
- Published
Validity and reliability of a clinical non-exercise method for assessment of cardiorespiratory fitness using seismocardiography
Hansen, Mikkel Thunestvedt, Rømer, Tue, Hoejgaard, A., Husted, Karina Louise Skov, Soerensen, K., Schmidt, S., Dela, Flemming & Helge, Jørn Wulff, 2021, In: European Heart Journal. 42, Suppl. 1, p. 3172-3172Research output: Contribution to journal › Conference abstract in journal › Research
- 2020
- Published
Cockayne syndrome proteins CSA and CSB maintain mitochondrial homeostasis through NAD+ signaling
Okur, M. N., Fang, E. F., Fivenson, E. M., Tiwari, V., Croteau, D. L. & Bohr, Vilhelm, Dec 2020, In: Aging Cell. 19, 12, p. e13268Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Risky business: How older ‘at risk’ people in Denmark evaluated their situated risk during the COVID-19 pandemic
Clotworthy, Amy & Westendorp, Rudi GJ, Dec 2020, In: Anthropology & Aging. 41, 2, p. 167-176 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
ETNK1 Mutations in Atypical Chronic Myeloid Leukemia Induce a Mutator Phenotype That Can be Reverted with Phosphoethanolamine
Fontana, D., Mauri, M., Renso, R., Docci, M., Crespiatico, I., Rost, L. M., Jang, M., Niro, A., D'Aliberti, D., Massimino, L., Bertagna, M., Zambrotta, G., Bossi, M., Citterio, S., Crescenzi, B., Fanelli, F., Cassina, V., Corti, R., Salerno, D., Nardo, L. & 10 others, , Nov 2020, In: Blood. 136, Suppl. 2, 3 p., LBA-5.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
The effectiveness of body age-based intervention in workplace health promotion: Results of a cohort study on 9851 Danish employees
Husted, Karina Louise Skov, Dandanell, S., Petersen, Janne, Dela, Flemming & Helge, Jørn Wulff, Sep 2020, In: PLoS ONE. 15, 9 September, 14 p., e0239337.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Center for Sund Aldring: Regeringen overser ældres ret til selvbestemmelse
Clotworthy, Amy & Westendorp, Rudi GJ, 19 May 2020, In: Altinget.dk. 1 p.Research output: Contribution to journal › Contribution to newspaper - Newspaper article › Communication
- Published
Cockayne syndrome group A and B proteins function in rRNA transcription through nucleolin regulation
Okur, M. N., Lee, J., Osmani, W., Kimura, R., Demarest, T. G., Croteau, D. L. & Bohr, Vilhelm, 18 Mar 2020, In: Nucleic Acids Research. 48, 5, p. 2473-2485 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Dietary habits, metabolic health and vitamin D status in Greenlandic children
Courraud, J., Quist, Jonas Salling, Kontopodi, E., Blomberg Jensen, M., Bjerrum, P. J., Helge, Jørn Wulff & Sørensen, K., 1 Jan 2020, In: Public Health Nutrition. 23, 5, p. 904-913Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Short-term NAD+ supplementation prevents hearing loss in mouse models of Cockayne syndrome
Okur, M. N., Mao, B., Kimura, R., Haraczy, S., Fitzgerald, T., Edwards-Hollingsworth, K., Tian, J., Osmani, W., Croteau, D. L., Kelley, M. W. & Bohr, Vilhelm, Jan 2020, In: npj Aging and Mechanisms of Disease. 6, 10 p., 1.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A Biological Age Model Designed for Health Promotion Interventions: Protocol for an Interdisciplinary Study for Model Development
Husted, Karina Louise Skov, Fogelstrom, M., Hulst, P., Brink-Kjaer, A., Henneberg, K., Sorensen, H. B. D., Dela, Flemming & Helge, Jørn Wulff, 2020, In: JMIR Research Protocols. 9, 10, 13 p., 19209.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Acetaminophen toxicity induces mitochondrial complex I inhibition in human liver tissue
Chrøis, K. M., Larsen, Steen, Pedersen, J. S., Rygg, M. O., Boilsen, A. E. B., Bendtsen, Flemming & Dela, Flemming, 2020, In: Basic & Clinical Pharmacology & Toxicology. 126, 1, p. 86-91Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Age-related macular degeneration: A two-level model hypothesis
Rozing, Maarten Pieter, Durhuus, J. A., Krogh Nielsen, M., Subhi, Y., Kirkwood, T. B. L., Westendorp, Rudi GJ & Sørensen, Torben Lykke, 2020, In: Progress in Retinal and Eye Research. 76, 100825.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
An analysis of the productivity and impact of clinical PhD theses from the University of Copenhagen
Rømer, Tue, Hansen, Mikkel Thunestvedt & Helge, Jørn Wulff, 2020, In: Danish Medical Journal. 67, 5, A12190731.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
An individual participant data analysis of prospective cohort studies on the association between subclinical thyroid dysfunction and depressive symptoms
Wildisen, L., Del Giovane, C., Moutzouri, E., Beglinger, S., Syrogiannouli, L., Collet, T-H., Cappola, A. R., Asvold, B. O., Bakker, S. J. L., Yeap, B. B., Almeida, O. P., Ceresini, G., Dullaart, R. P. F., Ferrucci, L., Grabe, H., Jukema, J. W., Nauck, M., Trompet, S., Voelzke, H., Westendorp, R. & 7 others, , 2020, In: Scientific Reports. 10, 1, 12 p., 19111.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Beta-aminoisobutyric acid is released by contracting human skeletal muscle and lowers insulin release from INS-1 832/3 cells by mediating mitochondrial energy metabolism
Barlow, J. P., Karstoft, K., Vigelsø, A., Gram, M., Helge, Jørn Wulff, Dela, Flemming, Pappan, K., O'Neil, D., Dunn, W. & Solomon, T. P. J., 2020, In: Metabolism open. 7, p. 100053Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cardioprotective effect of succinate dehydrogenase inhibition in rat hearts and human myocardium with and without diabetes mellitus
Jespersen, N. R., Hjortbak, M. V., Lassen, T. R., Støttrup, N. B., Johnsen, J., Tonnesen, P. T., Larsen, Steen, Kimose, H. H. & Bøtker, H. E., 2020, In: Scientific Reports. 10, 1, 15 p., 10344.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cardiovascular and metabolic health effects of team handball training in overweight women: Impact of prior experience
Hornstrup, T., Póvoas, S., Helge, Jørn Wulff, Melcher, Pia Grethe Sandfeld, Fristrup, B., Andersen, J. L., Møgelvang, R., Hansen, Peter Riis, Nybo, Lars & Krustrup, P., 2020, In: Scandinavian Journal of Medicine & Science in Sports. 30, 2, p. 281-294 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cellular senescence and chronological age in various human tissues: A systematic review and meta-analysis
Tuttle, C. S. L., Waaijer, M. E. C., Slee-Valentijn, M. S., Stijnen, T., Westendorp, Rudi GJ & Maier, A. B., 2020, In: Aging Cell. 19, 2, 11 p., e13083.Research output: Contribution to journal › Review › Research › peer-review
- Published
Circulating Thyroid Hormone Profile in Response to a Triiodothyronine Challenge in Familial Longevity
Zutinic, A., Blauw, G. J., Pijl, H., Ballieux, B. E., Westendorp, Rudi GJ, Roelfsema, F. & van Heemst, D., 2020, In: Endocrine Research. 4, 10, 9 p., bvaa117.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
DNA damage invokes mitophagy through a pathway involving Spata18
Dan, X., Babbar, M., Moore, A., Wechter, N., Tian, J., Mohanty, J. G., Croteau, D. L. & Bohr, Vilhelm, 2020, In: Nucleic Acids Research. 48, 12, p. 6611-6623 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
ETNK1 mutations induce a mutator phenotype that can be reverted with phosphoethanolamine
Fontana, D., Mauri, M., Renso, R., Docci, M., Crespiatico, I., Røst, L. M., Jang, M., Niro, A., D’aliberti, D., Massimino, L., Bertagna, M., Zambrotta, G., Bossi, M., Citterio, S., Crescenzi, B., Fanelli, F., Cassina, V., Corti, R., Salerno, D., Nardo, L. & 10 others, , 2020, In: Nature Communications. 11, 1, 16 p., 5938.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effect of Thyroid Hormone Therapy on Fatigability in Older Adults with Subclinical Hypothyroidism: A Nested Study within a Randomized Placebo-Controlled Trial
Stuber, M. J., Moutzouri, E., Feller, M., Del Giovane, C., Bauer, D. C., Blum, M. R., Collet, T. H., Gussekloo, J., Mooijaart, S. P., McCarthy, V. J. C., Aujesky, D., Westendorp, Rudi GJ, Stott, D. J., Glynn, N. W., Kearney, P. M., Rodondi, N. & Newman, A., 2020, In: Journals of Gerontology - Series A Biological Sciences and Medical Sciences. 75, 9, p. e89-e94 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effects of small-sided recreational team handball training on mechanical muscle function, body composition and bone mineralization in untrained young adults - A randomized controlled trial
Fristrup, B., Krustrup, P., Andersen, J. L., Hornstrup, T., Løwenstein, F. T., Larsen, M. A., Helge, Jørn Wulff, Póvoas, S. C. A. & Aagaard, P., 2020, In: P L o S One. 15, 11, 17 p., e0241359.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Exercise intensity and cardiovascular health outcomes after 12 months of football fitness training in women treated for stage I-III breast cancer: Results from the football fitness After Breast Cancer (ABC) randomized controlled trial
Uth, J., Fristrup, B., Sørensen, V., Helge, Eva Wulff, Christensen, M. K., Kjærgaard, J. B., Møller, T. K. T., Mohr, M., Helge, Jørn Wulff, Jørgensen, Niklas Rye, Rørth, M., Vadstrup, E. S. & Krustrup, P., 2020, In: Progress in Cardiovascular Diseases. 63, 6, p. 792-799 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Exercise training results in depot-specific adaptations to adipose tissue mitochondrial function
Mendham, A. E., Larsen, Steen, George, C., Adams, K., Hauksson, J., Olsson, T., Fortuin-de Smidt, M. C., Nankam, P. A. N., Hakim, O., Goff, L. M., Pheiffer, C. & Goedecke, J. H., 2020, In: Scientific Reports. 10, 1, 14 p., 3785.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Football as Medicine against type 2 diabetes and metabolic syndrome
de Sousa, M., Brito, J., Mohr, M., Nassis, G. P., Helge, Jørn Wulff, Pettersen, S. A., Andersen, T. R. & Krustrup, P., 2020, Football as Medicine: Prescribing Football for Global Health Promotion. Krustrup, P. & Parnell, D. (eds.). Routledge, p. 25-40 (Critical Research in Football).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
Frailty Index Status of Canadian Home Care Clients Improves With Exercise Therapy and Declines in the Presence of Polypharmacy
Larsen, R. T., Turcotte, L. A., Westendorp, Rudi GJ, Langberg, Henning & Hirdes, J. P., 2020, In: Journal of the American Medical Directors Association. 21, 6, p. 766-771 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Heterochromatin: an epigenetic point of view in aging
Lee, J., Kim, E. W., Croteau, D. L. & Bohr, Vilhelm, 2020, In: Experimental & Molecular Medicine. 52, 9, p. 1466-1474 9 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Hippocampal tau oligomerization early in tau pathology coincides with a transient alteration of mitochondrial homeostasis and DNA repair in a mouse model of tauopathy
Zheng, Jin, Akbari, M., Schirmer, C., Reynaert, M. L., Loyens, A., Lefebvre, B., Buée, L., Croteau, D. L., Galas, M. C. & Bohr, Vilhelm, 2020, In: Acta Neuropathologica Communications. 8, 1, 23 p., 25.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Interaction between RECQL4 and OGG1 promotes repair of oxidative base lesion 8-oxoG and is regulated by SIRT1 deacetylase
Duan, S., Han, X., Akbari, M., Croteau, D. L., Rasmussen, Lene Juel & Bohr, Vilhelm, 2020, In: Nucleic Acids Research. 48, 12, p. 6530–6546Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Interrelationships Between Pituitary Hormones as Assessed From 24-hour Serum Concentrations in Healthy Older Subjects
van der Spoel, E., Roelfsema, F., Akintola, A. A., Jansen, S. W., Slagboom, P. E., Westendorp, Rudi GJ, Blauw, G. J., Pijl, H. & van Heemst, D., 2020, In: Journal of Clinical Endocrinology & Metabolism. 105, 4, p. e1201–e1214 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Long-term exposure to air pollution and stroke incidence: A Danish Nurse cohort study
Amini, H., Dehlendorff, C., Lim, Y-H., Mehta, A., Jørgensen, J. T., Mortensen, L. H., Westendorp, R., Hoffmann, B., Loft, S., Cole-Hunter, T., Bräuner, E. V., Ketzel, M., Hertel, O., Brandt, J., Solvang Jensen, S., Christensen, J. H., Geels, C., Frohn, L. M., Backalarz, C., Simonsen, M. K. & 1 others, , 2020, In: Environment International. 142, 8 p., 105891.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Low-Grade Inflammation Is Not Present in Former Obese Males but Adipose Tissue Macrophage Infiltration Persists
Ara, I., Auerbach, P., Larsen, Steen, Mata, E., Stallknecht, Bente Merete, Ploug, Thorkil, Prats Gavalda, Clara & Helge, Jørn Wulff, 2020, In: Biomedicines. 8, 5, 10 p., 123.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Men Have a Stronger Monocyte-Derived Cytokine Production Response upon Stimulation with the Gram-Negative Stimulus Lipopolysaccharide than Women: A Pooled Analysis Including 15 Study Populations
Beenakker, K. G. M., Westendorp, Rudi GJ, de Craen, A. J. M., Chen, S., Raz, Y., Ballieux, B. E. P. B., Nelissen, R. G. H. H., Later, A. F. L., Huizinga, T. W., Slagboom, P. E., Boomsma, D. I. & Maier, A. B., 2020, In: Journal of Innate Immunity. 12, p. 142-153 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Menstrual cycle phase does not affect whole body peak fat oxidation rate during a graded exercise test
Frandsen, J., Pistoljevic, N., Quesada, J. P., Amaro-Gahete, F. J., Ritz, C., Larsen, S., Dela, Flemming & Helge, Jørn Wulff, 2020, In: Journal of Applied Physiology. 128, 3, p. 681-687 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mitochondrial adaptations to high intensity interval training in older females and males
Chrois, K. M., Dohlmann, T. L., Sogaard, D., Hansen, Camilla Collin, Dela, Flemming, Helge, Jørn Wulff & Larsen, Steen, 2020, In: European Journal of Sport Science. 20, 1, p. 135-145Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mitochondrial dysfunction in adults after out-of-hospital cardiac arrest
Wiberg, S., Stride, N., Bro-Jeppesen, J., Holmberg, M. J., Kjærgaard, J., Larsen, Steen, Donnino, M. W., Hassager, Christian & Dela, Flemming, 2020, In: European Heart Journal: Acute Cardiovascular Care. 9, 4, p. S138–S144 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Onset of Workplace Bullying and Risk of Weight Gain: A Multicohort Longitudinal Study
Xu, Tianwei, Magnusson Hanson, L. L., Clark, A. J., Ersbøll, A. K., Westerlund, H., Madsen, I. E. H., Rugulies, Reiner Ernst, Pentti, J., Stenholm, S., Vahtera, J., Sørensen, J. K., Nordentoft, M., Westendorp, Rudi GJ, Hansen, Åse Marie, Oksanen, T., Virtanen, M., Kivimäki, M. & Rod, Naja Hulvej, 2020, In: Obesity. 28, 11, p. 2216-2223 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Perceived stress and dementia: Results from the Copenhagen city heart study
Nabe-Nielsen, Kirsten, Rod, Naja Hulvej, Hansen, Åse Marie, Prescott, Eva, Grynderup, M. B., Islamoska, S., Ishtiak-Ahmed, K., Garde, Anne Helene, Gyntelberg, F., Mortensen, Erik Lykke, Thien Kieu Thi Phung, Waldemar, Gunhild & Westendorp, Rudi GJ, 2020, In: Aging & Mental Health. 24, 11, p. 1828-1836 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Plasma Metabolome Profiling of Resistance Exercise and Endurance Exercise in Humans
Morville, T., Sahl, Ronni Eg, Moritz, Thomas, Helge, Jørn Wulff & Clemmensen, Christoffer, 2020, In: Cell Reports. 33, 13, 14 p., 108554.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Reply to Dutheil et al
Frandsen, J., Pistoljevic, N., Quesada, J. P., Amaro-Gahete, F. J., Larsen, Steen, Dela, Flemming & Helge, Jørn Wulff, 2020, In: Journal of applied physiology (Bethesda, Md. : 1985). 129, 1, 1 p.Research output: Contribution to journal › Comment/debate › Research › peer-review
- Published
Shift work and incidence of dementia: A Danish Nurse Cohort study
Jørgensen, J. T., Hansen, J., Westendorp, Rudi GJ, Nabe-Nielsen, Kirsten, Stayner, L. T., Simonsen, M. K. & Andersen, Zorana Jovanovic, 2020, In: Alzheimer's and Dementia. 16, 9, p. 1268-1279 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Simvastatin improves mitochondrial respiration in peripheral blood cells
Durhuus, J. A., Hansson, Svenja, Morville, T., Kuhlman, A. B., Dohlmann, T. L., Larsen, Steen, Helge, Jørn Wulff, Angleys, M., Muniesa-Vargas, A., Bundgaard, J. R., Hickson, Ian David, Dela, Flemming, Desler, Claus & Rasmussen, Lene Juel, 2020, In: Scientific Reports. 10, 1, 17012.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Skeletal Effects of Levothyroxine for Subclinical Hypothyroidism in Older Adults: A TRUST Randomized Trial Nested Study
Gonzalez Rodriguez, E., Stuber, M., Del Giovane, C., Feller, M., Collet, T. H., Löwe, A. L., Blum, M. R., van Vliet, N. A., van Heemst, D., Kearney, P. M., Gussekloo, J., Mooijaart, S., Westendorp, Rudi GJ, Stott, D. J., Aeberli, D., Bauer, D. C., Hans, D. & Rodondi, N., 2020, In: The Journal of clinical endocrinology and metabolism. 105, 1, p. 336–343 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Spatial Transcriptomics Reveals Genes Associated with Dysregulated Mitochondrial Functions and Stress Signaling in Alzheimer Disease
Navarro, J. F., Croteau, D. L., Jurek, A., Andrusivova, Z., Yang, B., Wang, Y., Ogedegbe, B., Riaz, T., Støen, M., Desler, Claus, Rasmussen, Lene Juel, Tønjum, T., Galas, M. C., Lundeberg, J. & Bohr, Vilhelm, 2020, In: iScience. 23, 10, 42 p., 101556.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The NAD+-mitophagy axis in healthy longevity and in artificial intelligence-based clinical applications
Aman, Y., Frank, J., Lautrup, S. H., Matysek, A., Niu, Z., Yang, G., Shi, L., Bergersen, L. H., Storm-Mathisen, J., Rasmussen, Lene Juel, Bohr, Vilhelm, Nilsen, H. & Fang, E. F., 2020, In: Mechanisms of Ageing and Development. 185, 111194.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The relationship between peak fat oxidation and prolonged double-poling endurance exercise performance
Rømer, Tue, Hansen, Mikkel Thunestvedt, Frandsen, J., Larsen, Steen, Dela, Flemming & Helge, Jørn Wulff, 2020, In: Scandinavian Journal of Medicine & Science in Sports. 30, 11, p. 2044-2056Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Thyroid hormone receptor α in skeletal muscle is essential for T3-mediated increase in energy expenditure
Nicolaisen, T. S., Klein, A. B., Dmytriyeva, O., Lund, Jens, Ingerslev, L. R., Fritzen, Andreas Mæchel, Carl, Christian Strini, Lundsgaard, Anne-Marie, Frost, M., Ma, Tao, Schjerling, P., Gerhart-Hines, Zach, Flamant, F., Gauthier, K., Larsen, Steen, Richter, Erik A., Kiens, Bente & Clemmensen, Christoffer, 2020, In: F A S E B Journal. 34, 11, p. 15480-15491 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Towards Inclusive Healthcare Delivery: Potentials and Challenges of Human-Centred Design in Health Innovation Processes to Increase Healthy Aging
Sandholdt, Catharina Thiel, Cunningham, J., Westendorp, Rudi GJ & Kristiansen, Maria, 2020, In: International Journal of Environmental Research and Public Health. 17, 12, 9 p., 4551.Research output: Contribution to journal › Journal article › Research › peer-review
- 2019
- Published
Gaan we luisteren of meten?
Westendorp, Rudi GJ & Kusumastuti, S., 18 Nov 2019, In: Nederlands Tijdschrift voor Geneeskunde. 163, D4473.Research output: Contribution to journal › Comment/debate › Research
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The relationship between skeletal muscle mitochondrial citrate synthase activity and whole body oxygen uptake adaptations in response to exercise training.
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Meal induced gut hormone secretion is altered in aerobically trained compared to sedentary young healthy males
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Two weeks of metformin treatment enhances mitochondrial respiration in skeletal muscle of AMPK kinase dead but not wild type mice
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