- 2016
- Published
DNA damage markers in dermal fibroblasts in vitro reflect chronological donor age
Waaijer, M. E. C., Croco, E., Westendorp, Rudi GJ, Slagboom, P. E., Sedivy, J. M., Lorenzini, A. & Maier, A. B., 30 Jan 2016, In: Aging. 8, 1, p. 147-155 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Disentangling rectangularization and life span extension with the moving rectangle method
Schalkwijk, F. H., Koopman, J. J. E., Ghariq, E., de Beer, J. A. A., van Bodegom, D. & Westendorp, Rudi GJ, Mar 2016, In: Annals of Epidemiology. 26, 3, p. 218-221.e2 6 p.Research output: Contribution to journal › Letter › Research › peer-review
- Published
Effects of immobilization and aerobic training on proteins related to intramuscular substrate storage and metabolism in young and older men
Vigelsø Hansen, A., Gram, M., Wiuff, C., Hansen, C. N., Prats Gavalda, Clara, Dela, Flemming & Helge, Jørn Wulff, Mar 2016, In: European Journal of Applied Physiology. 116, 3, p. 481-494 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
An Internet-Based Physical Activity Intervention to Improve Quality of Life of Inactive Older Adults: A Randomized Controlled Trial
Broekhuizen, K., de Gelder, J., Wijsman, C. A., Wijsman, L. W., Westendorp, Rudi GJ, Verhagen, E., Slagboom, P. E., de Craen, A. J., van Mechelen, W., van Heemst, D., van der Ouderaa, F. & Mooijaart, S. P., Apr 2016, In: Journal of Medical Internet Research. 18, 4, p. 1-11 11 p., e74.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Calculating the Rate of Senescence From Mortality Data: An Analysis of Data From the ERA-EDTA Registry
Koopman, J. J. E., Rozing, M. P., Kramer, A., Abad, J. M., Finne, P., Heaf, J. G., Hoitsma, A. J., De Meester, J. M. J., Palsson, R., Postorino, M., Ravani, P., Wanner, C., Jager, K. J., van Bodegom, D. & Westendorp, Rudi GJ, Apr 2016, In: Journals of Gerontology. Series A: Biological Sciences & Medical Sciences. 71, 4, p. 468-474 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Hepatic mitochondrial oxidative phosphorylation is normal in obese patients with and without type 2 diabetes
Lund, M. T., Kristensen, M. D., Hansen, M., Tveskov, L., Floyd, A. K., Støckel, M., Vainer, B., Poulsen, Steen Seier, Helge, Jørn Wulff, Prats Gavalda, Clara & Dela, Flemming, 6 Apr 2016, In: The Journal of Physiology. 594, 15, p. 4351-4358 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Aerobic Exercise Training Increases Muscle Water Content in Obese Middle-Age Men
Mora-Rodríguez, R., Sanchez-Roncero, A., Fernández-Elías, V. E., Guadalupe-Grau, A., Ortega, J. F., Dela, Flemming & Helge, Jørn Wulff, May 2016, In: Medicine and Science in Sports and Exercise. 48, 5, p. 822-828 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Subclinical Thyroid Dysfunction and Depressive Symptoms among Elderly: A Prospective Cohort Study
Blum, M. R., Wijsman, L. W., Virgini, V. S., Bauer, D. C., den Elzen, W. P. J., Jukema, J. W., Buckley, B. M., de Craen, A. J. M., Kearney, P. M., Stott, D. J., Gussekloo, J., Westendorp, Rudi GJ, Mooijaart, S. P. & Rodondi, N., May 2016, In: Neuroendocrinology. 103, 3-4, p. 291-299 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
An Emerging Epidemic of Noncommunicable Diseases in Developing Populations Due to a Triple Evolutionary Mismatch
Koopman, J. J. E., van Bodegom, D., Ziem, J. B. & Westendorp, Rudi GJ, Jun 2016, In: American Journal of Tropical Medicine and Hygiene. 94, 6, p. 1189-1192 4 p.Research output: Contribution to journal › Comment/debate › Research › peer-review
- Published
The effects of diet- and RYGB-induced weight loss on insulin sensitivity in obese patients with and without type 2 diabetes
Hansen, M., Lund, M. T., Jørgensen, A. L. K., Palsøe, M. K., van Hall, Gerrit, Helge, Jørn Wulff & Dela, Flemming, Jun 2016, In: Acta Diabetologica. 53, 3, p. 423–432 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Acquired Localized Cutis Laxa due to Increased Elastin Turnover
Nygaard, R. H., Maynard, S., Schjerling, P., Kjær, M., Qvortrup, Klaus, Bohr, Vilhelm, Rasmussen, Lene Juel, Jemec, Gregor & Heidenheim, M., 14 Jun 2016, In: Case Reports in Dermatology. 8, 1, p. 42-51 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic variants determining survival and fertility in an adverse African environment: a population-based large-scale candidate gene association study
Koopman, J. J. E., Pijpe, J., Böhringer, S., van Bodegom, D., Eriksson, U. K., Sanchez-Faddeev, H., Ziem, J. B., Zwaan, B., Slagboom, P. E., de Knijff, P. & Westendorp, Rudi GJ, 27 Jun 2016, In: Aging. 8, 7, p. 1364-1383 20 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
RECQL4 Promotes DNA End Resection in Repair of DNA Double-Strand Breaks
Lu, H., Shamanna, R. A., Keijzers, G., Anand, R., Rasmussen, Lene Juel, Cejka, P., Croteau, D. L. & Bohr, Vilhelm, 28 Jun 2016, In: Cell Reports. 16, 1, p. 161-173 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effects of a 12-week alpine skiing intervention on endothelial progenitor cells, peripheral arterial tone and endothelial biomarkers in the elderly
Niederseer, D., Steidle-Kloc, E., Mayr, M., Müller, E. E., Cadamuro, J., Patsch, W., Dela, Flemming, Müller, E. & Niebauer, J., 1 Jul 2016, In: International Journal of Cardiology. 214, p. 343-347 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Hepatic fat content decreases with 3 weeks of intermittent fasting in obese patients with and without type 2 diabetes
Ingersen, Arthur, Helset, H., Skaaby, Stinna, Calov, M., Chabanova, E., Helge, Jørn Wulff & Dela, Flemming, Aug 2016, In: Diabetologia. 59, S1, p. S78-S78Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
Insulin Plays a Permissive Role for the Vasoactive Effect of GIP Regulating Adipose Tissue Metabolism in Humans
Asmar, M., Simonsen, L., rck626, rck626, Holst, Jens Juul, Dela, Flemming & Bülow, J., Aug 2016, In: Journal of Clinical Endocrinology and Metabolism. 101, 8, p. 3155-62 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
P16INK4a Positive Cells in Human Skin Are Indicative of Local Elastic Fiber Morphology, Facial Wrinkling, and Perceived Age
Waaijer, M. E. C., Gunn, D. A., Adams, P. D., Pawlikowski, J. S., Griffiths, C. E. M., van Heemst, D., Slagboom, P. E., Westendorp, Rudi GJ & Maier, A. B., Aug 2016, In: Journals of Gerontology. Series A: Biological Sciences & Medical Sciences. 71, 8, p. 1022-1028 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Secreted microvesicular miR-31 inhibits osteogenic differentiation of mesenchymal stem cells
Weilner, S., Schraml, E., Wieser, M., Messner, P., Schneider, K., Wassermann, K., Micutkova, L., Fortschegger, K., Maier, A. B., Westendorp, Rudi GJ, Resch, H., Wolbank, S., Redl, H., Jansen-Dürr, P., Pietschmann, P., Grillari-Voglauer, R. & Grillari, J., Aug 2016, In: Aging Cell. 15, 4, p. 744–754 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Visit-to-visit blood pressure variability and future functional decline in old age
Ogliari, G., Smit, R. A. J., Westendorp, Rudi GJ, Jukema, J. W., de Craen, A. J. M. & Sabayan, B., Aug 2016, In: Journal of Hypertension. 34, 8, p. 1544–1550 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Early and extraordinary peaks in physical performance come with a longevity cost
van de Vijver, P. L., van Bodegom, D. & Westendorp, Rudi GJ, 19 Aug 2016, In: Aging. 8, 8, p. 1822-1829 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
High-sensitivity cardiac troponin T is associated with cognitive decline in older adults at high cardiovascular risk
Wijsman, L. W., de Craen, A. J., Trompet, S., Sabayan, B., Muller, M., Stott, D. J., Ford, I., Welsh, P., Westendorp, Rudi GJ, Jukema, J. W., Sattar, N. & Mooijaart, S. P., Sep 2016, In: European Journal of Preventive Cardiology. 23, 13, p. 1383-1392 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
New horizons: Reablement - supporting older people towards independence
Aspinal, F., Glasby, J., Rostgaard, T., Tuntland, H. & Westendorp, Rudi GJ, 5 Sep 2016, In: Age and Ageing. 45, 5, p. 574-578 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The development, implementation and evaluation of a transitional care programme to improve outcomes of frail older patients after hospitalisation
Heim, N., Rolden, H., van Fenema, E. M., Weverling-Rijnsburger, A. W. E., Tuijl, J. P., Jue, P., Oleksik, A. M., de Craen, A. J. M., Mooijaart, S. P., Blauw, G. J., Westendorp, Rudi GJ, van der Mast, R. C. & van Everdinck, I. E. C., 5 Sep 2016, In: Age and Ageing. 45, 5, p. 642-651 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Associations of Various Health-Ratings with Geriatric Giants, Mortality and Life Satisfaction in Older People
Puvill, T., Lindenberg, J., Gussekloo, J., de Craen, A. J. M., Slaets, J. P. J. & Westendorp, Rudi GJ, 22 Sep 2016, In: P L o S One. 11, 9, p. 1-13 13 p., e0163499.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Actovegin, a non-prohibited drug increases oxidative capacity in human skeletal muscle
Søndergård, S. D., Dela, Flemming, Helge, Jørn Wulff & Larsen, Steen, Oct 2016, In: European Journal of Sport Science. 16, 7, p. 801-807 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
NAD(+) Replenishment Improves Lifespan and Healthspan in Ataxia Telangiectasia Models via Mitophagy and DNA Repair
Fang, E. F., Kassahun, H., Croteau, D. L., Scheibye-Knudsen, M., Marosi, K., Lu, H., Shamanna, R. A., Kalyanasundaram, S., Bollineni, R. C., Wilson, M. A., Iser, W. B., Wollman, B. N., Morevati, M., Li, J., Kerr, J. S., Lu, Q., Waltz, T. B., Tian, J., Sinclair, D. A., Mattson, M. P. & 2 others, , 11 Oct 2016, In: Cell Metabolism. 24, 4, p. 566-581 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Exercise promotes IL-6 release from legs in older men with minor response to unilateral immobilization
Reihmane, D., Gram, M., Vigelsø Hansen, A., Helge, Jørn Wulff & Dela, Flemming, Nov 2016, In: European Journal of Sport Science. 16, 8, p. 1039-1046 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Successful ageing: A study of the literature using citation network analysis
Kusumastuti, S., Derks, M. G. M., Tellier, S., Di Nucci, Ezio, Lund, Rikke, Mortensen, Erik Lykke & Westendorp, Rudi GJ, Nov 2016, In: Maturitas. 93, p. 4-12 9 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Thyroid Function within the Reference Range and the Risk of Stroke: An Individual Participant Data Analysis
Chaker, L., Baumgartner, C., den Elzen, W. P. J., Collet, T-H., Ikram, M. A., Blum, M. R., Dehghan, A., Drechsler, C., Luben, R. N., Portegies, M. L. P., Iervasi, G., Medici, M., Stott, D. J., Dullaart, R. P., Ford, I., Bremner, A., Newman, A. B., Wanner, C., Sgarbi, J. A., Dörr, M. & 22 others, , Nov 2016, In: The Journal of Clinical Endocrinology & Metabolism. 101, 11, p. 4270 – 4282 13 p., jc20162255.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cockayne syndrome group A and B proteins converge on transcription-linked resolution of non-B DNA
Scheibye-Knudsen, M., Tseng, A., Jensen, M. B., Scheibye-Alsing, K., Fang, E. F., Iyama, T., Bharti, S. K., Marosi, K., Froetscher, L., Kassahun, H., Eckley, D. M., Maul, R. W., Bastian, P., De, S., Ghosh, S., Nilsen, H., Goldberg, I. G., Mattson, M. P., Wilson, D. M. . III., Brosh, R. M. . J. & 2 others, , 1 Nov 2016, In: National Academy of Sciences. Proceedings. 113, 44, p. 12502-12507Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Perspectives on the Etiology of Violence in Later Life
Mysyuk, Y., Westendorp, Rudi GJ & Lindenberg, J., 1 Nov 2016, In: Journal of Interpersonal Violence. 31, 18, p. 3039-3062 24 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Familial Longevity Is Not Associated with Major Differences in the Hypothalamic–Pituitary–Gonadal Axis in Healthy Middle-Aged Men
van der Spoel, E., Roelfsema, F., Jansen, S. W., Akintola, A. A., Ballieux, B. E., Cobbaert, C. M., Blauw, G. J., Slagboom, P. E., Westendorp, Rudi GJ, Piji, H. & van Heemst, D., 9 Nov 2016, In: Frontiers in Endocrinology. 7, p. 1-7 7 p., 143.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Impact of physical and mental health on life satisfaction in old age: a population based observational study
Puvill, T., Lindenberg, J., de Craen, A. J. M., Slaets, J. P. J. & Westendorp, Rudi GJ, 25 Nov 2016, In: B M C Geriatrics. 16, p. 1-9 9 p., 194.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effekt af livsstilsændringer på vægttab og vedligeholdelse af vægttab
Lionett, S. B., Helge, Jørn Wulff, Dela, Flemming & Jørgensen, S. D., 30 Nov 2016, In: Ugeskrift for Laeger. 178, 22, p. 2-6 5 p., 2016;178:V07160509.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A ketogenic diet accelerates neurodegeneration in mice with induced mitochondrial DNA toxicity in the forebrain
Lauritzen, K. H., Hasan-Olive, M. M., Regnell, C. E., Kleppa, L., Scheibye-Knudsen, Morten, Gjedde, Albert, Klungland, A., Bohr, Vilhelm, Storm-Mathisen, J. & Bergersen, L. H., Dec 2016, In: Neurobiology of Aging. 48, p. 34-47Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cardiorespiratory fitness in 16 025 adults aged 18-91 years and associations with physical activity and sitting time
Eriksen, L., Grønbæk, M., Helge, Jørn Wulff & Tolstrup, J. S., Dec 2016, In: Scandinavian Journal of Medicine & Science in Sports. 26, 12, p. 1435-1443 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Growth hormone secretion is diminished and tightly controlled in humans enriched for familial longevity
van der Spoel, E., Jansen, S. W., Akintola, A. A., Ballieux, B. E., Cobbaert, C. M., Slagboom, P. E., Blauw, G. J., Westendorp, Rudi GJ, Pijl, H., Roelfsema, F. & van Heemst, D., Dec 2016, In: Aging Cell. 15, 6, p. 1126–1131 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Increased post-operative cardiopulmonary fitness in gastric bypass patients is explained by weight loss
Lund, M. T., Hansen, M., Wimmelmann, Cathrine Lawaetz, Taudorf, L. R., Helge, Jørn Wulff, Mortensen, Erik Lykke & Dela, Flemming, Dec 2016, In: Scandinavian Journal of Medicine & Science in Sports. 26, 12, p. 1428-1434 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Meta-analysis of genome-wide association studies of HDL cholesterol response to statins
Postmus, I., Warren, H. R., Trompet, S., Arsenault, B. J., Avery, C. L., Bis, J. C., Chasman, D. I., de Keyser, C. E., Deshmukh, H. A., Evans, D. S., Feng, Q., Li, X., Smit, R. A. J., Smith, A. V., Sun, F., Taylor, K. D., Arnold, A. M., Barnes, M. R., Barratt, B. J., Betteridge, J. & 68 others, , Dec 2016, In: Journal of Medical Genetics. 53, 12, p. 835-845 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
How older persons explain why they became victims of abuse
Mysyuk, Y., Westendorp, Rudi GJ & Lindenberg, J., 5 Dec 2016, In: Age and Ageing. 45, 5, p. 696-702 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2017
- Published
In Vitro and In Vivo Detection of Mitophagy in Human Cells, C. Elegans, and Mice
Fang, E. F., Palikaras, K., Sun, N., Fivenson, E. M., Spangler, R. D., Kerr, J. S., Cordonnier, S. A., Hou, Y., Dombi, E., Kassahun, H., Tavernarakis, N., Poulton, J., Nilsen, H. & Bohr, Vilhelm, 2017, In: Journal of Visualized Experiments. 129, e56301.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Anthropometry, DXA and leptin reflect subcutaneous but not visceral abdominal adipose tissue by MRI in 197 healthy adolescents
Tinggaard, J., Hagen, C. P., Christensen, A. N., Mouritsen, A., Mieritz, M. G., Wohlfahrt-Veje, C., Helge, Jørn Wulff, Beck, T. N., Fallentin, E., Larsen, R., Jensen, R. B., Juul, Anders & Main, Katharina Maria, 2017, In: Pediatric Research. 82, p. 620-628Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cockayne syndrome: Clinical features, model systems and pathways
Karikkineth, A. C., Scheibye-Knudsen, Morten, Fivenson, E., Croteau, D. L. & Bohr, Vilhelm, 2017, In: Ageing Research Reviews. 33, p. 3-17Research output: Contribution to journal › Review › Research › peer-review
- Published
Corporate culture: research can benefit
Westendorp, Rudi GJ & Wewer, Ulla M., 2017, In: Nature. 542, 7641, 1 p., 295.Research output: Contribution to journal › Journal article › Communication
- Published
Lack of effect of prolonged treatment with liraglutide on cardiac remodeling in rats after acute myocardial infarction
Kyhl, K., Lønborg, Jacob Thomsen, Hartmann, Bolette, Kissow, Hannelouise, Poulsen, Steen Seier, El Ali, Henrik H., Kjær, Andreas, Dela, Flemming, Engstrøm, Thomas & Treiman, M., 2017, In: Peptides. 93, p. 1-12Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Maximal Fat Oxidation is Related to Performance in an Ironman Triathlon
Frandsen, J., Vest, S. D., Dela, Flemming & Helge, Jørn Wulff, 2017, In: International Journal of Sports Medicine. 38, 13, p. 975-982Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mitophagy and Alzheimer's Disease: Cellular and Molecular Mechanisms
Kerr, J. S., Adriaanse, B. A., Greig, N. H., Mattson, M. P., Cader, M. Z., Bohr, Vilhelm & Fang, E. F., 2017, In: Trends in Neurosciences. 40, 3, p. 151-166 16 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Mitophagy in neurodegeneration and aging
Fivenson, E. M., Lautrup, S., Sun, N., Scheibye-Knudsen, Morten, Stevnsner, T., Nilsen, H., Bohr, Vilhelm & Fang, E. F., 2017, In: Neurochemistry International. 109, p. 202-209Research output: Contribution to journal › Review › Research › peer-review
- Published
NAD+ in Aging: Molecular Mechanisms and Translational Implications
Fang, E. F., Lautrup, S., Hou, Y., Demarest, T. G., Croteau, D. L., Mattson, M. P. & Bohr, Vilhelm, 2017, In: Trends in Molecular Medicine. 23, 10, p. 899-916 18 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Pre-ischaemic mitochondrial substrate constraint by inhibition of malate-aspartate shuttle preserves mitochondrial function after ischaemia–reperfusion
Jespersen, N. R., Yokota, T., Støttrup, N. B., Bergdahl, A., Pælestik, K. B., Povlsen, J. A., Dela, Flemming & Bøtker, H. E., 2017, In: Journal of Physiology. 595, 12, p. 3765-3780 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
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The relationship between skeletal muscle mitochondrial citrate synthase activity and whole body oxygen uptake adaptations in response to exercise training.
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Meal induced gut hormone secretion is altered in aerobically trained compared to sedentary young healthy males
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Two weeks of metformin treatment enhances mitochondrial respiration in skeletal muscle of AMPK kinase dead but not wild type mice
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Antioxidant enzymes and Nrf2/Keap1 in human skeletal muscle: Influence of age, sex, adiposity and aerobic fitness
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