- 2024
- Published
Protocol for the combined cardiometabolic deep phenotyping and registry-based 20-year follow-up study of the Inter99 cohort
Bjørnsbo, K. S., Brøns, C., Aadahl, M., Kampmann, F. B., Friis Bryde Nielsen, C., Lundbergh, B., Christensen, R. W., Kårhus, L. L., Madsen, A. L., Hansen, C. S., Nørgaard, K., Jørgensen, N. R., Suetta, C., Kjaer, M., Grarup, N., Kanters, J., Larsen, M., Køber, L., Kofoed, K. F., Loos, R. & 3 others, , 2024, In: BMJ Open. 14, 1, 10 p., e078501.Research output: Contribution to journal › Journal article › Research › peer-review
- 2023
- Published
Rev1 deficiency induces a metabolic shift in MEFs that can be manipulated by the NAD+ precursor nicotinamide riboside
Anugula, Sharath, Li, Zhiquan, Li, Yuan, Hendriksen, A., Christensen, P. B., Wang, L., Monk, J. M., de Wind, N., Bohr, Vilhelm, Desler, Claus, Naviaux, R. K. & Rasmussen, Lene Juel, 2023, In: Heliyon. 9, 6, e17392.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Is it all in the baseline? Trajectories of chair stand performance over 4 years and their association with grey matter structure in older adults
Demnitz, N., Gates, A. T., Mortensen, Erik Lykke, Garde, Ellen, Wimmelmann, Cathrine Lawaetz, Siebner, Hartwig Roman, Kjær, Michael & Boraxbekk, CJ, 2023, In: Human Brain Mapping. 44, 11, p. 4299-4309 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Muscle fascicle and sarcomere adaptation in response to Achilles tendon elongation in an animal model
Høffner, Rikke, Svensson, R. B., Dietrich-Zagonel, F., Schefte, D., Kjær, Michael, Eliasson, P. & Magnusson, Stig Peter, 2023, In: Journal of applied physiology (Bethesda, Md. : 1985). 135, 2, p. 326-333 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Detecting user experience issues from mHealth apps that support stroke caregiver needs: an analysis of user reviews
Lobo, E. H., Abdelrazek, M., Frølich, Anne, Rasmussen, Lene Juel, Livingston, P. M., Islam, S. M. S., Kensing, Finn & Grundy, J., 2023, In: Frontiers in Public Health. 11, 9 p., 1027667.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Pooled analysis of frontal lobe transcriptomic data identifies key mitophagy gene changes in Alzheimer's disease brain
Mei, T., Li, Yuan, Orduña Dolado, A., Li, Zhiquan, Andersson, Robin, Berliocchi, Laura & Rasmussen, Lene Juel, 2023, In: Frontiers in Aging Neuroscience. 15, 14 p., 1101216.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cyclin E overexpression in the Drosophila accessory gland induces tissue dysplasia
Molano-Fernández, M., Hickson, Ian David & Herranz, Hector, 2023, In: Frontiers in Cell and Developmental Biology. 10, 992253.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Galectin-7 reprograms skin carcinogenesis by fostering innate immune evasive programs
Pinto, N. A., Abba, M. C., Laporte, L., Pérez Sáez, J. M., Blidner, A. G., Torres, N. I., Morales, R. M., Gatto, S. G., Bach, C. A., Veigas, F., García Rivello, H. J., Song, P., Frederiksen, J. H., Rasmussen, Lene Juel, Poirier, F., Croci, D. O., Sundblad, V., Rabinovich, G. A. & Cerliani, J. P., 2023, In: Cell Death and Differentiation. 30, p. pages906–921Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Viscoelastic Capillary Flow Cytometry
Serhatlioglu, M., Jensen, E. A., Niora, M., Hansen, A. T., Nielsen, Christian Friberg, Jansman, M. M. T., Hosta-rigau, L., Dziegiel, Morten Hanefeld, Berg-sørensen, K., Hickson, Ian David & Kristensen, A., 2023, In: Advanced NanoBiomed Research. 3, 2, 2200137.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Tendon properties in a mouse model of severe osteogenesis imperfecta
Sinkam, L., Boraschi-Diaz, I., Svensson, R. B., Kjær, Michael, Komarova, S. V., Bergeron, R., Rauch, F. & Veilleux, L. N., 2023, In: Connective Tissue Research. 64, 3, p. 285-293Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Metabolic reprogramming by Acly inhibition using SB-204990 alters glucoregulation and modulates molecular mechanisms associated with aging
Sola-García, A., Cáliz-Molina, M. Á., Espadas, I., Petr, M., Panadero-Morón, C., González-Morán, D., Martín-Vázquez, M. E., Narbona-Pérez, Á. J., López-Noriega, L., Martínez-Corrales, G., López-Fernández-Sobrino, R., Carmona-Marin, L. M., Martínez-Force, E., Yanes, O., Vinaixa, M., López-López, D., Reyes, J. C., Dopazo, J., Martín, F., Gauthier, B. R. & 3 others, , 2023, In: Communications Biology . 6, 250.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Histone malonylation is regulated by SIRT5 and KAT2A
Zhang, R., Bons, J., Scheidemantle, G., Liu, X., Bielska, O., Carrico, C., Rose, J., Heckenbach, Indra John, Scheibye-Knudsen, Morten, Schilling, B. & Verdin, E., 2023, In: iScience. 26, 3, 106193.Research output: Contribution to journal › Journal article › Research › peer-review
- 2022
- Published
RANKL regulates testicular cancer growth and Denosumab treatment has suppressive effects on GCNIS and advanced seminoma
Andreassen, C. H., Lorenzen, M., Nielsen, J. E., Kafai Yahyavi, S., Toft, Birgitte Grønkær, Ingerslev, L. R., Clemmensen, Christoffer, Rasmussen, Lene Juel, Bokemeyer, C., Juul, Anders, Jørgensen, A. & Jensen, M. B., 2022, In: British Journal of Cancer. 127, p. 408-421Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Duplex DNA and BLM regulate gate opening by the human TopoIIIα-RMI1-RMI2 complex
Bakx, J. A. M., Biebricher, A. S., King, G. A., Christodoulis, P., Sarlós, K., Bizard, A. H., Hickson, Ian David, Wuite, G. J. L. & Peterman, E. J. G., 2022, In: Nature Communications. 13, 1, 584.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
RAD51 protects human cells from transcription-replication conflicts
Bhowmick, Rahul, Lerdrup, Mads, Gadi, Sampath Amitash, Rossetti, G. G., Singh, Manika Indrajit, Liu, Ying, Halazonetis, T. D. & Hickson, Ian David, 2022, In: Molecular Cell. 82, 18, p. 3366-3381.e9Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Exercise in patients with hip osteoarthritis - effects on muscle and functional performance: A randomized trial
Bieler, T., Kristensen, A. L. R., Nyberg, M., Magnusson, Stig Peter, Kjær, Michael & Beyer, N., 2022, In: Physiotherapy Theory and Practice. 38, 12, p. 1946-1957Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A novel splice variant of Elp3/Kat9 regulates mitochondrial tRNA modification and function
Boutoual, R., Jo, H., Heckenbach, Indra John, Tiwari, R., Kasler, H., Lerner, C. A., Shah, S., Schilling, B., Calvanese, V., Rardin, M. J., Scheibye-Knudsen, Morten & Verdin, E., 2022, In: Scientific Reports. 12, 14804.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effects of Heavy Slow Resistance Training Combined With Corticosteroid Injections or Tendon Needling in Patients With Lateral Elbow Tendinopathy A 3-Arm Randomized Double-Blinded Placebo-Controlled Study
Couppé, Christian, Døssing, S., Bulow, P. M., Siersma, Volkert Dirk, Zilmer, C. K., Bang, C. W., Høffner, Rikke, Kracht, M., Hogg, P., Edstrom, G., Kjær, Michael & Magnusson, Stig Peter, 2022, In: American Journal of Sports Medicine. 50, 10, p. 2787-2796 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Partial inhibition of mitochondrial-linked pyrimidine synthesis increases tumorigenic potential and lysosome accumulation
Desler, Claus, Durhuus, J. A., Hansen, T. L. L., Anugula, Sharath, Zelander, N. T., Bøggild, S. & Rasmussen, Lene Juel, 2022, In: Mitochondrion. 64, p. 73-81 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effects of age on muscle power, postural control and functional capacity after short-term immobilization and retraining
Elam, C., Hvid, L. G., Christensen, U., Kjær, Michael, Magnusson, Stig Peter, Aagaard, P., Bunketorp Käll, L. & Suetta, Charlotte, 2022, In: Journal of Musculoskeletal Neuronal Interactions. 22, 4, p. 486-497 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
PICH Supports Embryonic Hematopoiesis by Suppressing a cGAS-STING-Mediated Interferon Response
Geng, X., Zhang, C., Li, M., Wang, J., Ji, F., Feng, H., Xing, M., Li, F., Zhang, L., Li, W., Chen, Z., Hickson, Ian David, Shen, H. & Ying, S., 2022, In: Advanced Science. 9, 7, 2103837.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The hallmarks of aging
Gilmour, B. C., Bergersen, L. H. & Fang, E. F., 2022, Molecular, Cellular, and Metabolic Fundamentals of Human Aging. Academic Press, p. 1-6 6 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
Systems modelling predicts chronic inflammation and genomic instability prevent effective mitochondrial regulation during biological ageing
Guimera, A. M., Clark, P., Wordsworth, J., Anugula, Sharath, Rasmussen, Lene Juel & Shanley, D. P., 2022, In: Experimental Gerontology. 166, 9 p., 111889.Research output: Contribution to journal › Review › Research › peer-review
- Published
Nuclear morphology is a deep learning biomarker of cellular senescence
Heckenbach, Indra John, Mkrtchyan, Garik, Ben Ezra, Michael, Bakula, Daniela Janina, Madsen, Jakob Sture, Nielsen, M. H., Oró, D., Osborne, Brenna, Covarrubias, A. J., Idda, M. L., Gorospe, M., Mortensen, Laust Hvas, Verdin, E., Westendorp, Rudi GJ & Scheibye-Knudsen, Morten, 2022, In: Nature Aging. 2, 8, p. 742-755 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Persistent Deficits after an Achilles Tendon Rupture: A Narrative Review
Høffner, Rikke, Svensson, R. B., Bjerregaard, N., Kjær, Michael & Magnusson, Stig Peter, 2022, In: Translational Sports Medicine. 2022Research output: Contribution to journal › Review › Research › peer-review
- Published
The regional turnover of cartilage collagen matrix in late-stage human knee osteoarthritis
Jørgensen, A. E. M., Agergaard, J., Schjerling, Peter, Heinemeier, K. M., van Hall, Gerrit & Kjær, Michael, 2022, In: Osteoarthritis and Cartilage. 30, 6, p. 886-895Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The proteomic profile of the human myotendinous junction
Karlsen, Anders, Gonzalez-Franquesa, A., Jakobsen, J. R., Krogsgaard, Michael R., Koch, M., Kjær, Michael, Schiaffino, S., Mackey, Abigail & Deshmukh, Atul Shahaji, 2022, In: iScience. 25, 2, 19 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Lactate receptor HCAR1 regulates neurogenesis and microglia activation after neonatal hypoxia-ischemia
Kennedy, L., Glesaaen, E. R., Palibrk, V., Pannone, M., Wang, W., Al-Jabri, A., Suganthan, R., Meyer, N., Austbø, M. L., Lin, X., Bergersen, L. H., Bjørås, M. & Rinholm, J. E., 2022, In: eLife. 11, 21 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
NIH SenNet Consortium to map senescent cells throughout the human lifespan to understand physiological health
Lee, P. J., Benz, C. C., Blood, P., Börner, K., Campisi, J., Chen, F., Daldrup-Link, H., De Jager, P., Ding, L., Duncan, F. E., Eickelberg, O., Fan, R., Finkel, T., Furman, D., Garovic, V., Gehlenborg, N., Glass, C., Heckenbach, I., Joseph, Z. B., Katiyar, P. & 48 others, , 2022, In: Nature Aging. 2, 12, p. 1090-1100 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genomic instability and aging
Li, Zhiquan, Anugula, Sharath & Rasmussen, Lene Juel, 2022, Aging: From Fundamental Biology to Societal Impact. Oliveira, P. J. & Malva, J. O. (eds.). Academic Press, p. 275-295 21 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
Pathological Tendon Histology in Early and Chronic Human Patellar Tendinopathy
Malmgaard-Clausen, N. M., Kjær, Michael & Dakin, S. G., 2022, In: Translational Sports Medicine. 2022, 2799665.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Meeting Report: Aging Research and Drug Discovery
Meron, E., Thaysen, M., Angeli, S., Antebi, A., Barzilai, N., Baur, J. A., Bekker-Jensen, S., Birkisdottir, M., Bischof, E., Bruening, J., Brunet, A., Buchwalter, A., Cabreiro, F., Cai, S., Chen, B. H., Ermolaeva, M., Ewald, C. Y., Ferrucci, L., Florian, M. C., Fortney, K. & 58 others, , 2022, In: Aging. 14, 2, p. 530-543 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
High-confidence cancer patient stratification through multiomics investigation of DNA repair disorders
Mkrtchyan, Garik, Veviorskiy, A., Izumchenko, E., Shneyderman, A., Pun, F. W., Ozerov, I. V., Aliper, A., Zhavoronkov, A. & Scheibye-Knudsen, Morten, 2022, In: Cell Death and Disease. 13, 11, 999.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Autophagy guards tendon homeostasis
Montagna, C., Svensson, R. B., Bayer, M. L., Rizza, S., Maiani, E., Yeung, Ching-Yan Chloé, Filomeni, G. & Kjær, Michael, 2022, In: Cell Death and Disease. 13, 4, 402.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Colorectal cancer incidences in Lynch syndrome: a comparison of results from the prospective lynch syndrome database and the international mismatch repair consortium
The European Hereditary Tumour Group (EHTG) and the International Mismatch Repair Consortium (IMRC), T. E. H. T. G. (. A. T. I. M. R. C. (., 2022, In: Hereditary Cancer in Clinical Practice. 20, 36.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
ATRX-Deficient High-Grade Glioma Cells Exhibit Increased Sensitivity to RTK and PDGFR Inhibitors
Pladevall Morera, David, Castejón-Griñán, M., Aguilera, P., Gaardahl, K., Ingham, Andreas, Brosnan-Cashman, J. A., Meeker, A. K. & Lopez-Contreras, Andres, 2022, In: Cancers. 14, 7, 1790.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
New hallmarks of ageing: a 2022 Copenhagen ageing meeting summary
Schmauck-Medina, T., Molière, A., Lautrup, S., Zhang, J., Chlopicki, S., Madsen, H. B., Cao, S., Soendenbroe, C., Mansell, E., Vestergaard, M. B., Li, Z., Shiloh, Y., Opresko, P. L., Egly, J. M., Kirkwood, T., Verdin, E., Bohr, V. A., Cox, L. S., Stevnsner, T., Rasmussen, L. J. & 1 others, , 2022, In: Aging. 14, 16, p. 6829-6839 11 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Development of a fiber-based microfluidic flow cytometry platform using viscoelastic fluids for polydisperse particle suspensions
Serhatlioglu, M., Jensen, E. A., Niora, M., Hansen, A. T., Nielsen, Christian Friberg, Theresia Jansman, M. M., Hosta-Rigau, L., Dziegiel, Morten Hanefeld, Berg-Sørensen, K., Hickson, Ian David & Kristensen, A., 2022, In: Proceedings of SPIE - The International Society for Optical Engineering. 12198, 9 p., 1219802.Research output: Contribution to journal › Conference article › Research › peer-review
- Published
Ribosome impairment regulates intestinal stem cell identity via ZAKɑ activation
Silva, J., Alkan, F., Ramalho, S., Snieckute, Goda, Prekovic, S., Garcia, A. K., Hernández-Pérez, S., van der Kammen, R., Barnum, D., Hoekman, L., Altelaar, M., Zwart, W., Suijkerbuijk, S. J. E., Bekker-Jensen, Simon Holst & Faller, W. J., 2022, In: Nature Communications. 13, 1, 4492.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Preserved stem cell content and innervation profile of elderly human skeletal muscle with lifelong recreational exercise
Soendenbroe, C., Dahl, C. L., Meulengracht, C., Tamáš, M., Svensson, R. B., Schjerling, Peter, Kjær, Michael, Andersen, J. L. & Mackey, Abigail, 2022, In: The Journal of Physiology. 600, 8, p. 1969-1989Research output: Contribution to journal › Journal article › Research › peer-review
- Published
CNOT6: A Novel Regulator of DNA Mismatch Repair
Song, P., Liu, S., Liu, D., Keijzers, G., Bakula, Daniela Janina, Duan, S., de Wind, N., Ye, Z., Vakhrushev, Sergey, Scheibye-Knudsen, Morten & Rasmussen, Lene Juel, 2022, In: Cells. 11, 3, 521.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
PICH acts as a force-dependent nucleosome remodeler
Spakman, D., Clement, T. V. M., Biebricher, A. S., King, G. A., Singh, Manika Indrajit, Hickson, Ian David, Peterman, E. J. G. & Wuite, G. J. L., 2022, In: Nature Communications. 13, 7277.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Human derived tendon cells contribute to myotube formation in vitro
Tsuchiya, Y., Bayer, M. L., Schjerling, Peter, Soendenbroe, C. & Kjær, Michael, 2022, In: Experimental Cell Research. 417, 1, 113164.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Prevention of Cell Death by Activation of Hydroxycarboxylic Acid Receptor 1 (GPR81) in Retinal Explants
Vohra, Rupali, Sanz-Morello, B., Tams, A. L. M., Mouhammad, Zaynab Ahmad, Freude, Kristine, Hannibal, Jens, Aldana, Blanca, Bergersen, L. H. & Kolko, Miriam, 2022, In: Cells. 11, 13, 2098.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Circadian regulation of protein cargo in extracellular vesicles
Yeung, Ching-Yan Chloé, Dondelinger, F., Schoof, E. M., Georg, B., Lu, Y., Zheng, Z., Zhang, J., Hannibal, Jens, Fahrenkrug, J. & Kjær, Michael, 2022, In: Science Advances. 8, 14, 13 p., eabc9061.Research output: Contribution to journal › Journal article › Research › peer-review
- 2021
- Published
Mechanical properties and UTE-T2* in Patellar tendinopathy: The effect of load magnitude in exercise-based treatment
Agergaard, A. S., Svensson, R. B., Høffner, Rikke, Hansen, P., Couppé, Christian, Kjær, Michael & Magnusson, Stig Peter, 2021, In: Scandinavian Journal of Medicine and Science in Sports. 31, 10, p. 1981-1990Research output: Contribution to journal › Journal article › Research › peer-review
- Published
UTE T2* mapping of tendinopathic patellar tendons: an MRI reproducibility study
Agergaard, A. S., Malmgaard-Clausen, N. M., Svensson, R. B., Nybing, J. D., Boesen, Mikael Ploug, Kjær, Michael, Magnusson, Stig Peter & Hansen, P., 2021, In: Acta Radiologica. 62, 2, p. 215-224 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
How Do We Explore Heterogeneity in Turnover of Musculoskeletal Proteins?
Agergaard, J. & Kjær, Michael, 2021, In: Function. 2, 4, 2 p., 034.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cytosolic self-DNA—A potential source of chronic inflammation in aging
Akbari, M., Shanley, D. P., Bohr, Vilhelm & Rasmussen, Lene Juel, 2021, In: Cells. 10, 12, 3544.Research output: Contribution to journal › Review › Research › peer-review
- Published
Chronic Sequelae After Muscle Strain Injuries: Influence of Heavy Resistance Training on Functional and Structural Characteristics in a Randomized Controlled Trial
Bayer, M. L., Hoegberget-Kalisz, M., Svensson, R. B., Hjortshoej, M. H., Olesen, J. L., Nybing, J. D., Boesen, Mikael Ploug, Magnusson, Stig Peter & Kjær, Michael, 2021, In: American Journal of Sports Medicine. 49, 10, p. 2783-2794 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Longevity medicine: upskilling the physicians of tomorrow
Bischof, E., Scheibye-Knudsen, Morten, Siow, R. & Moskalev, A., 2021, In: The Lancet Healthy Longevity. 2, 4, p. e187-e188Research output: Contribution to journal › Comment/debate › Research › peer-review
- Published
Habitual side-specific loading leads to structural, mechanical, and compositional changes in the patellar tendon of young and senior lifelong male athletes
Couppé, Christian, Svensson, R. B., Skovlund, S. V., Jensen, Jacob Kildevang, Eriksen, C. S., Malmgaard-Clausen, N. M., Nybing, J. D., Kjær, Michael & Magnusson, Stig Peter, 2021, In: Journal of Applied Physiology. 131, 4, p. 1187-1199Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Right-left asymmetry in corticospinal tract microstructure and dexterity are uncoupled in late adulthood
Demnitz, N., Madsen, K. S., Johnsen, L. K., Kjær, Michael, Boraxbekk, CJ & Siebner, Hartwig Roman, 2021, In: NeuroImage. 240, 118405.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
EX-vivo whole blood stimulation with A2E does not elicit an inflammatory cytokine response in patients with age-related macular degeneration
Durhuus, J. A., Rozing, Maarten Pieter, Nielsen, M. K., Molbech, C. R., Keijzers, G., Scheibye-Knudsen, Morten, Rasmussen, Lene Juel, Westendorp, Rudi GJ & Sørensen, Torben Lykke, 2021, In: Scientific Reports. 11, 1, 8226.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Reduction of lamin B receptor levels by miR-340-5p disrupts chromatin, promotes cell senescence and enhances senolysis
Herman, A. B., Anerillas, C., Harris, S. C., Munk, R., Martindale, J. L., Yang, X., Mazan-Mamczarz, K., Zhang, Y., Heckenbach, Indra John, Scheibye-Knudsen, Morten, De, S., Sen, P., Abdelmohsen, K. & Gorospe, M., 2021, In: Nucleic Acids Research. 49, 13, p. 7389-7405 17 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
ATP induces contraction of cultured brain capillary pericytes, via activation of P2Y type purinergic receptors
Hørlyck, S., Cai, Changsi, Helms, H. C., Lauritzen, Martin & Larsen, Birger Brodin, 2021, In: American Journal of Physiology: Heart and Circulatory Physiology. 320, p. H699–H712 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
RNA-sequencing and immunofluorescence of the myotendinous junction of mature horses and humans
Jakobsen, J. R., Schjerling, Peter, Svensson, R. B., Buhl, Rikke, Carstensen, Helena, Koch, M., Rindom Krogsgaard, M. R., Kjær, Michael & Mackey, Abigail, 2021, In: American journal of physiology. Cell physiology. 321, p. C453–C470Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Adipocytes are present at human and murine myotendinous junctions
Jakobsen, J. R., Jakobsen, N. R., Mackey, Abigail, Knudsen, A. B., Hannibal, Jens, Koch, M., Kjær, Michael & Krogsgaard, Michael R., 2021, In: Translational Sports Medicine. 4, 2, p. 223-230Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Instability in NAD+ metabolism leads to impaired cardiac mitochondrial function and communication
Lauritzen, K. H., Olsen, M. B., Ahmed, M. S., Yang, K., Rinholm, J. E., Bergersen, L. H., Esbensen, Q. Y., Sverkeli, L. J., Ziegler, M., Attramadal, H., Halvorsen, B., Aukrust, P. & Yndestad, A., 2021, In: eLife. 10, 23 p., 59828.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Musculoskeletal sports medicine injuries in special operations forces soldiers
Lendal, M. S. & Kjær, Michael, 2021, In: Translational Sports Medicine. 4, 6, p. 872-881 10 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
mHealth applications to support caregiver needs and engagement during stroke recovery: A content review
Lobo, E. H., Frølich, Anne, Kensing, Finn, Rasmussen, Lene Juel, Livingston, P. M., Grundy, J. & Abdelrazek, M., 2021, In: Research in Nursing and Health. 44, 1, p. 213-225Research output: Contribution to journal › Review › Research › peer-review
- Published
Magnetic Resonance T-2* Is Increased in Patients With Early-Stage Achilles and Patellar Tendinopathy
Malmgaard-Clausen, N. M., Tran, P., Svensson, R. B., Hansen, Philip, Nybing, J. D., Magnusson, Stig Peter & Kjær, Michael, 2021, In: Journal of Magnetic Resonance Imaging. 54, 3, p. 832-839Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Collagens in primary frozen shoulder: expression of collagen mRNA isoforms in the different phases of the disease
Marker, L., Schjerling, P., Mackey, Abigail, Hansen, T., Jakobsen, J., Kjær, Michael & Krogsgaard, Michael R., 2021, In: Rheumatology. 60, 8, p. 3879-3887Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Tendon blood flow, angiogenesis, and tendinopathy pathogenesis
Merkel, M. F. R., Hellsten, Ylva, Magnusson, Stig Peter & Kjær, Michael, 2021, In: Translational Sports Medicine. 4, 6, p. 756-771 16 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Age-related myofiber atrophy in old mice is reversed by ten weeks voluntary high-resistance wheel running
Olesen, A. T., Alchow-Moller, L., Bendixen, R. D., Kjær, Michael, Svensson, R. B., Andersen, J. L. & Magnusson, Stig Peter, 2021, In: Experimental Gerontology. 143, 111150.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mitochondrial-Linked De Novo Pyrimidine Biosynthesis Dictates Human T-Cell Proliferation but Not Expression of Effector Molecules
Peeters, M. J. W., Aehnlich, P., Pizzella, A., Mølgaard, K., Seremet, T., Met, Özcan, Rasmussen, Lene Juel, thor Straten, P. & Desler, Claus, 2021, In: Frontiers in Immunology. 12, 718863.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A cross-sectional study of functional and metabolic changes during aging through the lifespan in male mice
Petr, Michael Angelo, Alfaras, I., Krawcyzk, M., Bair, W. N., Mitchell, S. J., Morrell, C. H., Studenski, S. A., Price, N. L., Fishbein, K. W., Spencer, R. G., Scheibye-Knudsen, Morten, Lakatta, E. G., Ferrucci, L., Aon, M. A., Bernier, M. & de Cabo, R., 2021, In: eLife. 10, 25 p., e62952.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic insights into biological mechanisms governing human ovarian ageing
Ruth, K. S., Day, F. R., Hussain, J., Martinez-Marchal, A., Aiken, C. E., Azad, A., Thompson, D. J., Knoblochova, L., Abe, H., Tarry-Adkins, J. L., Gonzalez, J. M., Fontanillas, P., Claringbould, A., Bakker, O. B., Sulem, P., Walters, R. G., Terao, C., Turon, S., Horikoshi, M., Lin, K. & 36 others, , 2021, In: Nature. 596, p. 393-397Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Resting in bed - how quickly does the muscle lose its nerve?
Soendenbroe, C., Mackey, Abigail & Kjær, Michael, 2021, In: The Journal of Physiology. 599, 12, p. 2995-2996Research output: Contribution to journal › Editorial › Research
- Published
Bloom syndrome DNA helicase deficiency is associated with oxidative stress and mitochondrial network changes
Subramanian, V., Rodemoyer, B., Shastri, V., Rasmussen, Lene Juel, Desler, Claus & Schmidt, K. H., 2021, In: Scientific Reports. 11, 2157.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mechanical properties of human patellar tendon collagen fibrils. An exploratory study of aging and sex
Svensson, R. B., Eriksen, C. S., Tran, P. H. T., Kjær, Michael & Magnusson, Stig Peter, 2021, In: Journal of the Mechanical Behavior of Biomedical Materials. 124, 104864.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mutual stimulatory signaling between human myogenic cells and rat cerebellar neurons
Tamáš, M., Pankratova, Stanislava, Schjerling, Peter, Soendenbroe, C., Yeung, C. C., Pennisi, C. P., Jakobsen, J. R., Krogsgaard, Michael R., Kjær, Michael & Mackey, Abigail, 2021, In: Physiological Reports. 9, 21, e15077.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Variation in the risk of colorectal cancer in families with Lynch syndrome: a retrospective cohort study
The International Mismatch Repair Consortium, T. I. M. R. C., Jul 2021, In: The Lancet Oncology. 22, 7, p. 1014-1022 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2020
- Published
Supraphysiological protection from replication stress does not extend mammalian lifespan
Albers, E., Avram, Alexandra Ioana, Sbroggio, M., Fernandez-Capetillo, O. & Lopez-Contreras, Andres, 2020, In: Aging. 12, 7, p. 5612-5624 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The NAD+-mitophagy axis in healthy longevity and in artificial intelligence-based clinical applications
Aman, Y., Frank, J., Lautrup, S. H., Matysek, A., Niu, Z., Yang, G., Shi, L., Bergersen, L. H., Storm-Mathisen, J., Rasmussen, Lene Juel, Bohr, Vilhelm, Nilsen, H. & Fang, E. F., 2020, In: Mechanisms of Ageing and Development. 185, 111194.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
ATR expands embryonic stem cell fate potential in response to replication stress
Atashpaz, S., Samadi Shams, S., Martin Gonzalez, Javier, Sebestyén, E., Arghavanifard, N., Gnocchi, A., Albers, E., Minardi, S., Faga, G., Soffientini, P., Allievi, E., Cancila, V., Bachi, A., Fernández-Capetillo, Ó., Tripodo, C., Ferrari, F., Lopez-Contreras, Andres & Costanzo, V., 2020, In: eLife. 9, e54756.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
MitophAging: Mitophagy in Aging and Disease
Bakula, Daniela Janina & Scheibye-Knudsen, Morten, 2020, In: Frontiers in Cell and Developmental Biology. 8, 16 p., 239.Research output: Contribution to journal › Review › Research › peer-review
- Published
Influence of the integrin alpha-1 subunit and its relationship with high-fat diet upon extracellular matrix synthesis in skeletal muscle and tendon
Bayer, M. L., Svensson, R. B., Schjerling, P., Williams, A. S., Wasserman, D. H. & Kjær, Michael, 2020, In: Cell and Tissue Research. 381, 1, p. 177-187Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The many lives of type IA topoisomerases
Bizard, A. H. & Hickson, Ian David, 2020, In: Journal of Biological Chemistry. 295, 20, p. 7138-7153 16 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Mitochondrial Function in Gilles de la Tourette Syndrome Patients With and Without Intragenic IMMP2L Deletions
Bjerregaard, Victoria Alexandra, Schönewolf-Greulich, B., Rasmussen, Lene Juel, Desler, Claus & Tümer, Asuman Zeynep, 2020, In: Frontiers in Neurology. 11, 9 p., 163.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The ZGRF1 Helicase Promotes Recombinational Repair of Replication-Blocking DNA Damage in Human Cells
Brannvoll, A., Xue, X., Kwon, Y., Kompocholi, Smaragda, Simonsen, Anne Katrine Wrist, Bagge, Keerthana Stine Viswalingam, Gonzalez, L., Hickson, Ian David, Østergaard, Vibe Hallundbæk, Mankouri, H. W., Sung, P. & Lisby, Michael, 2020, In: Cell Reports. 32, 1, 25 p., 107849.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Tumour predisposition and cancer syndromes as models to study gene–environment interactions
Carbone, M., Arron, S. T., Beutler, B., Bononi, A., Cavenee, W., Cleaver, J. E., Croce, C. M., D’Andrea, A., Foulkes, W. D., Gaudino, G., Groden, J. L., Henske, E. P., Hickson, I. D., Hwang, P. M., Kolodner, R. D., Mak, T. W., Malkin, D., Monnat, R. J., Novelli, F., Pass, H. I. & 3 others, , 2020, In: Nature Reviews Cancer. 20, p. 533–549Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Senescent cells promote tissue NAD+ decline during ageing via the activation of CD38+ macrophages
Covarrubias, A. J., Kale, A., Perrone, R., Lopez-Dominguez, J. A., Pisco, A. O., Kasler, H. G., Schmidt, M. S., Heckenbach, I., Kwok, R., Wiley, C. D., Wong, H. S., Gibbs, E., Iyer, S. S., Basisty, N., Wu, Q., Kim, I. J., Silva, E., Vitangcol, K., Shin, K. O., Lee, Y. M. & 11 others, , 2020, In: Nature Metabolism. 2, 11, p. 1265-1283 19 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Modification of oxygen consumption and blood flow in mouse somatosensory cortex by cell-type-specific neuronal activity
Dahlqvist, M. K., Thomsen, Kirsten Joan, Postnov, D. D. & Lauritzen, Martin, 2020, In: Journal of Cerebral Blood Flow and Metabolism. 40, 10, p. 2010-2025 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Two integrated and highly predictive functional analysis-based procedures for the classification of MSH6 variants in Lynch syndrome
Drost, M., Tiersma, Y., Glubb, D., Kathe, S., van Hees, S., Calléja, F., Zonneveld, J. B. M., Boucher, K. M., Ramlal, R. P. E., Thompson, B. A., Rasmussen, Lene Juel, Greenblatt, M. S., Lee, A., Spurdle, A. B., Tavtigian, S. V. & de Wind, N., 2020, In: Genetics in Medicine. 22, p. 847–856Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Interaction between RECQL4 and OGG1 promotes repair of oxidative base lesion 8-oxoG and is regulated by SIRT1 deacetylase
Duan, S., Han, X., Akbari, M., Croteau, D. L., Rasmussen, Lene Juel & Bohr, Vilhelm, 2020, In: Nucleic Acids Research. 48, 12, p. 6530–6546Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Simvastatin improves mitochondrial respiration in peripheral blood cells
Durhuus, J. A., Hansson, Svenja, Morville, T., Kuhlman, A. B., Dohlmann, T. L., Larsen, Steen, Helge, Jørn Wulff, Angleys, M., Muniesa-Vargas, A., Bundgaard, J. R., Hickson, Ian David, Dela, Flemming, Desler, Claus & Rasmussen, Lene Juel, 2020, In: Scientific Reports. 10, 1, 17012.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The effect of 4 months exercise training on systemic biomarkers of cartilage and bone turnover in hip osteoarthritis patients
Ellegaard, M., Bieler, T., Beyer, N., Kjær, Michael & Jørgensen, Niklas Rye, 2020, In: Translational Sports Medicine. 3, 1, p. 16-25Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Folate stress induces SLX1- and RAD51-dependent mitotic DNA synthesis at the fragile X locus in human cells
Garribba, L., Bjerregaard, Victoria Alexandra, Gonçalves Dinis, M. M., Özer, Ö., Wu, Wei, Sakellariou, D., Pena-Diaz, J., Hickson, Ian David & Liu, Ying, 2020, In: Proceedings of the National Academy of Sciences of the United States of America. 117, 28, p. 16527-16536 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Maintenance of muscle strength following a one-year resistance training program in older adults
Gylling, A. T., Bloch-Ibenfeldt, M., Eriksen, C. S., Ziegler, A. K., Wimmelmann, Cathrine Lawaetz, Bækgaard, M., Boraxbekk, CJ, Siebner, Hartwig Roman, Mortensen, Erik Lykke & Kjær, Michael, 2020, In: Experimental Gerontology. 139, 111049.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The influence of prolonged strength training upon muscle and fat in healthy and chronically diseased older adults
Gylling, A. T., Eriksen, C. S., Garde, Ellen, Wimmelmann, Cathrine Lawaetz, Reislev, N. L., Bieler, T., Ziegler, A. K., Andersen, K. W., Bauer, C., Dideriksen, K., Bækgaard, M., Mertz, K. H., Bayer, M. L., Bloch-Ibenfeldt, M., Boraxbekk, CJ, Siebner, Hartwig Roman, Mortensen, Erik Lykke & Kjær, Michael, 2020, In: Experimental Gerontology. 136, 110939.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Influence of Nodal signalling on pluripotency factor expression, tumour cell proliferation and cisplatin-sensitivity in testicular germ cell tumours
Harpelunde Poulsen, K., Nielsen, J. E., Grønkær Toft, B., Joensen, Ulla Nordström, Rasmussen, Lene Juel, Blomberg Jensen, M., Mitchell, R. T., Juul, Anders, Rajpert-De Meyts, E. & Jørgensen, Anders, 2020, In: BMC Cancer. 20, 1, 14 p., 349.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Early Growth Response Genes Increases Rapidly After Mechanical Overloading and Unloading in Tendon Constructs
Herchenhan, A., Dietrich-Zagonel, F., Schjerling, P., Kjær, Michael & Eliasson, P., 2020, In: Journal of Orthopaedic Research. 38, 1, p. 173-181Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Histology and Function of the Rectus Abdominis Muscle in Patients With Incisional Hernia
Jensen, K. K., Oma, E., Kjær, Michael, Jørgensen, Lars Nannestad & Andersen, J. L., 2020, In: Journal of Surgical Research. 253, p. 245-251 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Macrophage Subpopulations and the Acute Inflammatory Response of Elderly Human Skeletal Muscle to Physiological Resistance Exercise
Jensen, S. M., Bechshøft, C. J. L., Heisterberg, M. F., Schjerling, P., Andersen, J. L., Kjær, Michael & Mackey, Abigail, 2020, In: Frontiers in Physiology. 11, 15 p., 811.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Preserved capacity for satellite cell proliferation, regeneration, and hypertrophy in the skeletal muscle of healthy elderly men
Karlsen, Anders, Soendenbroe, C., Malmgaard‐clausen, N. M., Wagener, F., Moeller, C. E., Senhaji, Z., Damberg, K., Andersen, J. L., Schjerling, P., Kjær, Michael & Mackey, Abigail, 2020, In: The FASEB Journal. 34, 5, p. 6418-6436Research output: Contribution to journal › Journal article › Research › peer-review
- Published
What is the impact of acute inflammation on muscle performance in geriatric patients?
Karlsen, Anders, Mackey, Abigail, Suetta, Charlotte & Kjær, Michael, 1 Jun 2020, In: Experimental Gerontology. 138, 8 p., 111008.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Adrenergic Regulation of Energy Metabolism
Kjær, Michael & Lange, Kai, 2020, Endocrinology of Physical Activity and Sport. Humana Press, p. 153-159 (Contemporary Endocrinology).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
TIP60 in aging and neurodegeneration
Li, Zhiquan & Rasmussen, Lene Juel, 2020, In: Ageing Research Reviews. 64, 101195.Research output: Contribution to journal › Review › Research › peer-review
- Published
Mitophagy and Neuroprotection
Lou, G., Palikaras, K., Lautrup, S., Scheibye-Knudsen, Morten, Tavernarakis, N. & Fang, E. F., 2020, In: Trends in Molecular Medicine. 26, 1, p. 8-20Research output: Contribution to journal › Review › Research › peer-review
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Life-long endurance exercise in humans: circulating levels of inflammatory markers and leg muscle size
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Activation of the ATR kinase by the RPA-binding protein ETAA1
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Is There a Link between Mitochondrial Reserve Respiratory Capacity and Aging?
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Protocol for the combined cardiometabolic deep phenotyping and registry-based 20-year follow-up study of the Inter99 cohort
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