- Published
'Spreading depression of Leão' and its emerging relevance to acute brain injury in humans
Lauritzen, Martin & Strong, A. J., 2016, In: Journal of Cerebral Blood Flow and Metabolism. 37, 5, p. 1553-1570Research output: Contribution to journal › Review › Research › peer-review
- Published
14-3-3 checkpoint regulatory proteins interact specifically with DNA repair protein human exonuclease 1 (hEXO1) via a semi-conserved motif
Andersen, S. D., Keijzers, G., Rampakakis, E., Engels, K., Luhn, P., El-Shemerly, M., Nielsen, Finn Cilius, Du, Y., May, A., Bohr, Vilhelm, Ferrari, S., Zannis-Hadjopoulos, M., Fu, H. & Rasmussen, Lene Juel, Mar 2012, In: D N A Repair. 11, 3, p. 267-77 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
18F-fluorodeoxyglucose and PET/CT for noninvasive study of exercise-induced glucose uptake in rat skeletal muscle and tendon
Skovgaard, D., Kjær, Michael, El Ali, Henrik H. & Kjær, Andreas, May 2009, In: European Journal of Nuclear Medicine and Molecular Imaging. 36, 5, p. 859-68 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
3-D ultrastructure and collagen composition of healthy and overloaded human tendon: evidence of tenocyte and matrix buckling
Pingel, Jessica, Lu, Y., Starborg, T., Fredberg, U., Langberg, Henning, Nedergaard, A., Weis, M., Eyre, D., Kjær, Michael & Kadler, K. E., 9 Feb 2014, In: Journal of Anatomy. 224, 5, p. 548–555 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
3-Hydroxybutyrate regulates energy metabolism and induces BDNF expression in cerebral cortical neurons
Marosi, K., Kim, S. W., Moehl, K., Scheibye-Knudsen, Morten, Cheng, A., Cutler, R., Camandola, S. & Mattson, M. P., Dec 2016, In: Journal of Neurochemistry. 139, 5, p. 769-781 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
53BP1 nuclear bodies form around DNA lesions generated by mitotic transmission of chromosomes under replication stress
Lukas, Claudia, Savic, V., Bekker-Jensen, Simon Holst, Doil, C., Neumann, B., Pedersen, R. S., Grøfte, M., Chan, K. L., Hickson, Ian David, Bartek, J. & Lukas, Jiri, 1 Mar 2011, In: Nature Cell Biology. 13, 3, p. 243-53 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Helicobacter pylori infection affects mitochondrial function and DNA repair, thus, mediating genetic instability in gastric cells
Machado, A. M. D., Desler, C., Boggild, S., Strickertsson, J. A. B., Friis-Hansen, Lennart Jan, Figueiredo, C., Seruca, R. & Rasmussen, Lene Juel, 2013, In: Mechanisms of Ageing and Development. 134, 10, p. 460-466 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Rev1 deficiency induces a metabolic shift in MEFs that can be manipulated by the NAD+ precursor nicotinamide riboside
Anugula, Sharath, Li, Zhiquan, Li, Yuan, Hendriksen, A., Christensen, P. B., Wang, L., Monk, J. M., de Wind, N., Bohr, Vilhelm, Desler, Claus, Naviaux, R. K. & Rasmussen, Lene Juel, 2023, In: Heliyon. 9, 6, e17392.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A Ketogenic Diet Improves Mitochondrial Biogenesis and Bioenergetics via the PGC1α-SIRT3-UCP2 Axis
Hasan-Olive, M. M., Lauritzen, K. H., Ali, M., Rasmussen, Lene Juel, Storm-Mathisen, J. & Bergersen, L. H., 2019, In: Neurochemical Research. 44, 1, p. 22-37 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A Molecular Toolbox to Engineer Site-Specific DNA Replication Perturbation
Larsen, N. B., Hickson, Ian David & Mankouri, H. W., 2018, Genome Instability: Methods and Protocols. Springer, Vol. 1672. p. 295-309 15 p. (Methods in molecular biology (Clifton, N.J.)).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
A Novel Rrm3 Function in Restricting DNA Replication via an Orc5-Binding Domain Is Genetically Separable from Rrm3 Function as an ATPase/Helicase in Facilitating Fork Progression
Syed, S., Desler, Claus, Rasmussen, Lene Juel & Schmidt, K. H., Dec 2016, In: P L o S Genetics. 12, 12, 28 p., e1006451.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A Role for BLM in Double-Strand Break Repair Pathway Choice: Prevention of CtIP/Mre11-Mediated Alternative Nonhomologous End-Joining.
Grabarz, A., Guirouilh-Barbat, J., Barascu, A., Pennarun, G., Genet, D., Rass, E., Germann, S. M., Bertrand, P., Hickson, Ian David & Lopez, B. S., 17 Oct 2013, In: Cell Reports. 5, 1, p. 21-28 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A Single Conserved Residue Mediates Binding of the Ribonucleotide Reductase Catalytic Subunit RRM1 to RRM2 and Is Essential for Mouse Development
Specks, J., Lecona, E., Lopez-Contreras, Andres & Fernandez-Capetillo, O., Sep 2015, In: Molecular and Cellular Biology. 35, 17, p. 2910-2917 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A Small Molecule Inhibitor of the BLM Helicase Modulates Chromosome Stability in Human Cells
Nguyen, G. H., Dexheimer, T. S., Rosenthal, A. S., Chu, W. K., Singh, D. K., Mosedale, G., Bachrati, C. Z., Schultz, L., Sakurai, M., Savitsky, P., Abu, M., McHugh, P. J., Bohr, Vilhelm, Harris, C. C., Jadhav, A., Gileadi, O., Maloney, D. J., Simeonov, A. & Hickson, Ian David, 24 Jan 2013, In: Chemistry & Biology. 20, 1, p. 55-62 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A critical role for astrocytes in hypercapnic vasodilation in brain
Howarth, C., Sutherland, B. A., Choi, H. B., Martin, C., Lind, Barbara Lykke, Khennouf, Lila, LeDue, J. M., Pakan, J. M. P., Ko, R. W., Ellis-Davies, G. C. R., Lauritzen, Martin, Sibson, N. R., Buchan, A. M. & MacVicar, B. A., 2017, In: The Journal of Neuroscience. 37, 9, p. 2403-2414 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A cross-sectional study of functional and metabolic changes during aging through the lifespan in male mice
Petr, Michael Angelo, Alfaras, I., Krawcyzk, M., Bair, W. N., Mitchell, S. J., Morrell, C. H., Studenski, S. A., Price, N. L., Fishbein, K. W., Spencer, R. G., Scheibye-Knudsen, Morten, Lakatta, E. G., Ferrucci, L., Aon, M. A., Bernier, M. & de Cabo, R., 2021, In: eLife. 10, 25 p., e62952.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A defined human aging phenome
Andreassen, Søren Norge, Ben Ezra, Michael & Scheibye-Knudsen, Morten, 2019, In: Aging. 11, 15, p. 5786-5806 21 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A functional assay–based procedure to classify mismatch repair gene variants in Lynch syndrome
Drost, M., Tiersma, Y., Thompson, B. A., Frederiksen, J. H., Keijzers, G., Glubb, D., Kathe, S., Osinga, J., Westers, H., Pappas, L., Boucher, K. M., Molenkamp, S., Zonneveld, J. B., van Asperen, C. J., Goldgar, D. E., Wallace, S. S., Sijmons, R. H., Spurdle, A. B., Rasmussen, L. J., Greenblatt, M. S. & 2 others, , 2019, In: Genetics in Medicine. 21, p. 1486–1496Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A high-fat diet and NAD+ activate sirt1 to rescue premature aging in cockayne syndrome
Scheibye-Knudsen, M., Mitchell, S. J., Fang, E. F., Iyama, T., Ward, T., Wang, J., Dunn, C. A., Singh, N., Veith, S., Hasan-Olive, M. M., Mangerich, A., Wilson, M. A., Mattson, M. P., Bergersen, L. H., Cogger, V. C., Warren, A., Le Couteur, D. G., Moaddel, R., Wilson, D. M., Croteau, D. L. & 2 others, , 4 Nov 2014, In: Cell Metabolism. 20, 5, p. 840-855 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A ketogenic diet accelerates neurodegeneration in mice with induced mitochondrial DNA toxicity in the forebrain
Lauritzen, K. H., Hasan-Olive, M. M., Regnell, C. E., Kleppa, L., Scheibye-Knudsen, Morten, Gjedde, Albert, Klungland, A., Bohr, Vilhelm, Storm-Mathisen, J. & Bergersen, L. H., Dec 2016, In: Neurobiology of Aging. 48, p. 34-47Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A new cellular stress response that triggers centriolar satellite reorganization and ciliogenesis
Villumsen, B. H., Danielsen, J. R., Povlsen, L., Sylvestersen, K. B., Merdes, A., Beli, P., Yang, Y., Choudhary, Chunaram, Nielsen, Michael Lund, Mailand, Niels & Bekker-Jensen, Simon Holst, 11 Oct 2013, In: E M B O Journal. 32, 23, p. 3029-3040Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A new home for the Journal of Cerebral Blood Flow and Metabolism
Dirnagl, U. & Lauritzen, Martin, Feb 2016, In: Journal of Cerebral Blood Flow and Metabolism. 36, 2, p. 277Research output: Contribution to journal › Editorial › Research › peer-review
- Published
A new non-catalytic role for ubiquitin ligase RNF8 in unfolding higher-order chromatin structure
Luijsterburg, M. S., Acs, K., Ackermann, L., Wiegant, W. W., Bekker-Jensen, Simon Holst, Larsen, D. H., Khanna, K. K., van Attikum, H., Mailand, Niels & Dantuma, N. P., 2012, In: E M B O Journal. 31, 11, p. 2511-27 17 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A novel TPR-BEN domain interaction mediates PICH-BEND3 association
Pitchai, G. P., Kaulich, M., Bizard, A. H., Mesa, Pablo, Yao, Q., Sarlos, K., Streicher, W. W., Nigg, E. A., Montoya, Guillermo & Hickson, Ian David, 2017, In: Nucleic Acids Research. 19, 2, p. 11413–11424Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A novel antirecombinase gains PARIty
Mankouri, H. W., Chu, W. K. & Hickson, Ian David, Jan 2012, In: Molecular Cell. 45, 1, p. 6-7 2 p.Research output: Contribution to journal › Review › Research › peer-review
Most downloads
-
2506
downloads
Life-long endurance exercise in humans: circulating levels of inflammatory markers and leg muscle size
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
2009
downloads
Activation of the ATR kinase by the RPA-binding protein ETAA1
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
1717
downloads
Is There a Link between Mitochondrial Reserve Respiratory Capacity and Aging?
Research output: Contribution to journal › Journal article › Research › peer-review
Published
Latest publications
Protocol for the combined cardiometabolic deep phenotyping and registry-based 20-year follow-up study of the Inter99 cohort
Research output: Contribution to journal › Journal article › Research › peer-review
Muscle fascicle and sarcomere adaptation in response to Achilles tendon elongation in an animal model
Research output: Contribution to journal › Journal article › Research › peer-review
Pooled analysis of frontal lobe transcriptomic data identifies key mitophagy gene changes in Alzheimer's disease brain
Research output: Contribution to journal › Journal article › Research › peer-review