Damage and Repair

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  1. 2015
  2. Published

    Associations of subjective vitality with DNA damage, cardiovascular risk factors and physical performance

    Maynard, S., Keijzers, G., Hansen, Åse Marie, Osler, Merete, Molbo, Drude, Bendix, L., Møller, Peter, Loft, Steffen, Moreno-Villanueva, M., Bürkle, A., Hvitby, C. P., Schurman, S. H., Stevnsner, T. V., Rasmussen, Lene Juel, Avlund, K. & Bohr, Vilhelm, Jan 2015, In: Acta Physiologica (Print). 213, 1, p. 156-170 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Centriolar satellites: key mediators of centrosome functions

    Tollenaere, M. A. X., Mailand, Niels & Bekker-Jensen, Simon Holst, Jan 2015, In: Cellular and molecular life sciences : CMLS. 73, 1, p. 11-23 13 p.

    Research output: Contribution to journal › Review › Research › peer-review

  4. Published

    Mitochondria in health and disease: 3rd annual conference of society for mitochondrial research and medicine - 19-20 december 2013 - bengaluru, India

    Durhuus, J. A., Desler, Claus & Rasmussen, Lene Juel, Jan 2015, In: Mitochondrion. 20, p. 7-12 6 p.

    Research output: Contribution to journal › Conference article › Research › peer-review

  5. Published

    Proteome-wide analysis of SUMO2 targets in response to pathological DNA replication stress in human cells

    Bursomanno, S., Beli, P., Khan, A. M., Minocherhomji, S., Wagner, S. A., Bekker-Jensen, Simon Holst, Mailand, Niels, Choudhary, Chunaram, Hickson, Ian David & Liu, Ying, Jan 2015, In: DNA Repair. 25, p. 84-96 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Ubiquitin-SUMO Circuitry Controls Activated Fanconi Anemia ID Complex Dosage in Response to DNA Damage

    Gibbs-Seymour, I., Oka, Y., Rajendra, E., Weinert, B. T., Passmore, L. A., Patel, K. J., Olsen, Jesper Velgaard, Choudhary, Chunaram, Bekker-Jensen, Simon Holst & Mailand, Niels, Jan 2015, In: Molecular Cell. 57, 1, p. 150-64 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Acute MUS81 depletion leads to replication fork slowing and a constitutive DNA damage response

    Xing, M., Wang, X., Palmai-Pallag, T., Shen, H., Helleday, T., Hickson, Ian David & Ying, S., 2015, In: OncoTarget. 6, 35, p. 37638-37646 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Crystal structure of the Bloom's syndrome helicase indicates a role for the HRDC domain in conformational changes

    Newman, J. A., Savitsky, P., Allerston, C. K., Bizard, A. H., Özer, Ö., Sarlós, K., Liu, Ying, Pardon, E., Steyaert, J., Hickson, Ian David & Gileadi, O., 2015, In: Nucleic Acids Research. 43, 10, p. 5221-35 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    FBH1 influences DNA replication fork stability and homologous recombination through ubiquitylation of RAD51

    Chu, W. K., Payne, M. J., Beli, P., Hanada, K., Choudhary, C. & Hickson, Ian David, 2015, In: Nature Communications. 6, 7 p., 5931.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    GABAA Receptor-Mediated Bidirectional Control of Synaptic Activity, Intracellular Ca2+, Cerebral Blood Flow, and Oxygen Consumption in Mouse Somatosensory Cortex In Vivo

    Jessen, S. B., Brazhe, A., Lind, Barbara Lykke, Mathiesen, C., Thomsen, K., Jensen, K. & Lauritzen, Martin, 2015, In: Cerebral Cortex. 25, 9, p. 2594-2609 16 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Human exonuclease 1 (EXO1) activity characterization and its function on FLAP structures

    Keijzers, G., Bohr, Vilhelm & Rasmussen, Lene Juel, 2015, In: Bioscience Reports. 35, 3, 13 p., e00206.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Influence of ornithine decarboxylase antizymes and antizyme inhibitors on agmatine uptake by mammalian cells

    Ramos-Molina, B., Lopez-Contreras, Andres, Lambertos, A., Dardonville, C., Cremades, A. & Peñafiel, R., 2015, In: Amino Acids. 47, 5, p. 1025-34 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    PICH promotes sister chromatid disjunction and co-operates with topoisomerase II in mitosis

    Nielsen, Christian Friberg, Huttner, D., Bizard, A. H., Hirano, S., Li, T., Palmai-Pallag, T., Bjerregaard, Victoria Alexandra, Liu, Ying, Nigg, E. A., Wang, L. H. & Hickson, Ian David, 2015, In: Nature Communications. 6, 15 p., 8962.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Preserved skeletal muscle protein anabolic response to acute exercise and protein intake in well-treated rheumatoid arthritis patients

    Mikkelsen, U. R., Dideriksen, K., Andersen, M. B., Boesen, A., Malmgaard-Clausen, N. M., Sørensen, I. J., Schjerling, Peter, Kjær, Michael & Holm, L., 2015, In: Arthritis Research & Therapy (Print). 17, p. 271

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Prospective multi-centre randomised trial comparing induction of labour with a double-balloon catheter versus dinoprostone

    Løkkegaard, Ellen Christine Leth, Lundstrøm, M., Kjær, Michael, Christensen, I. J., Pedersen, H. B. & Nyholm, H., 2015, In: Journal of Obstetrics and Gynaecology. 35, 8, p. 797-802 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Regulation of SUMO2 Target Proteins by the Proteasome in Human Cells Exposed to Replication Stress

    Bursomanno, S., McGouran, J. F., Kessler, B. M., Hickson, Ian David & Liu, Ying, 2015, In: Journal of Proteome Research. 14, 4, p. 1687-99 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. 2014
  18. Published

    Mechanistic insight into the interaction of BLM helicase with intra-strand G-quadruplex structures

    Chatterjee, S., Zagelbaum, J., Savitsky, P., Sturzenegger, A., Huttner, D., Janscak, P., Hickson, Ian David, Gileadi, O. & Rothenberg, E., 24 Nov 2014, In: Nature Communications. 5, p. 1-12 12 p., 5556.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Dynamics of the DNA repair proteins WRN and BLM in the nucleoplasm and nucleoli

    Bendtsen, K. M., Jensen, M. B., May, A., Rasmussen, Lene Juel, Trusina, Ala, Bohr, Vilhelm & Jensen, Mogens Høgh, 14 Nov 2014, In: European Biophysics Journal. 43, 10-11, p. 509-516

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    A high-fat diet and NAD+ activate sirt1 to rescue premature aging in cockayne syndrome

    Scheibye-Knudsen, M., Mitchell, S. J., Fang, E. F., Iyama, T., Ward, T., Wang, J., Dunn, C. A., Singh, N., Veith, S., Hasan-Olive, M. M., Mangerich, A., Wilson, M. A., Mattson, M. P., Bergersen, L. H., Cogger, V. C., Warren, A., Le Couteur, D. G., Moaddel, R., Wilson, D. M., Croteau, D. L. & 2 others, De Cabo, R. & Bohr, Vilhelm, 4 Nov 2014, In: Cell Metabolism. 20, 5, p. 840-855 16 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Low tendon stiffness and abnormal ultrastructure distinguish classic Ehlers-Danlos syndrome from benign joint hypermobility syndrome in patients

    Nielsen, R. H., Couppé, Christian, Jensen, J. K., Olsen, M. R., Heinemeier, K. M., Malfait, F., Symoens, S., De Paepe, A., Schjerling, Peter, Magnusson, Stig Peter, Remvig, L. & Kjær, Michael, Nov 2014, In: FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 28, 11, p. 4668-4676 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Renal-Retinal Ciliopathy Gene Sdccag8 Regulates DNA Damage Response Signaling

    Airik, R., Slaats, G. G., Guo, Z., Weiss, A., Khan, N., Ghosh, A., Hurd, T. W., Bekker-Jensen, Simon Holst, Schrøder, J. M., Elledge, S. J., Andersen, J. S., Kispert, A., Castelli, M., Boletta, A., Giles, R. H. & Hildebrandt, F., Nov 2014, In: Journal of the American Society of Nephrology:JASN. 25, 11, p. 2573-83 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    The role of RecQ helicases in non-homologous end-joining

    Keijzers, G., Maynard, S., Shamanna, R. A., Rasmussen, Lene Juel, Croteau, D. L. & Bohr, Vilhelm, Nov 2014, In: Critical Reviews in Biochemistry and Molecular Biology. 49, 6, p. 463-472 10 p.

    Research output: Contribution to journal › Review › Research › peer-review

  24. Published

    Tendon protein synthesis rate in classic Ehlers-Danlos patients can be stimulated with insulin-like growth factor-I

    Nielsen, R. H., Holm, L., Jensen, J. K., Heinemeier, K. M., Remvig, L. & Kjær, Michael, 1 Oct 2014, In: Journal of Applied Physiology. 117, 7, p. 694-698 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Tus-Ter as a tool to study site-specific DNA replication perturbation in eukaryotes

    Larsen, N. B., Hickson, Ian David & Mankouri, H. W., 1 Oct 2014, In: Cell Cycle. 13, 19, p. 2994-8 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    Associations between xerostomia, histopathological alterations, and autonomic innervation of labial salivary glands in men in late midlife

    Sørensen, Christiane Elisabeth, Larsen, J. O., Reibel, Jesper, Lauritzen, Martin, Mortensen, Erik Lykke, Osler, Merete & Pedersen, Anne Marie Lynge, Sep 2014, In: Experimental Gerontology. 57, p. 211-217 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    Subclinical cognitive decline in middle-age is associated with reduced task-induced deactivation of the brain's default mode network

    Hansen, N. L., Lauritzen, Martin, Mortensen, Erik Lykke, Osler, Merete, Avlund, K., Fagerlund, Birgitte & Rostrup, E., Sep 2014, In: Human Brain Mapping. 35, 9, p. 4488-98 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    Enterococcus faecalis Infection and Reactive Oxygen Species Down-Regulates the miR-17-92 Cluster in Gastric Adenocarcinoma Cell Culture

    Strickertsson, J. A. B., Rasmussen, Lene Juel & Friis-Hansen, Lennart Jan, 28 Aug 2014, In: Genes. 5, 3, p. 726-38 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    Impact of bacterial infections on aging and cancer: Impairment of DNA repair and mitochondrial function of host cells

    Strickertsson, J. A. B., Desler, Claus & Rasmussen, Lene Juel, Aug 2014, In: Experimental Gerontology. 56, p. 164-174 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    Life-long endurance running is associated with reduced glycation and mechanical stress in connective tissue

    Couppé, Christian, Svensson, R. B., Grosset, J., Kovanen, V., Nielsen, R. H., Olsen, M. R., Larsen, J. O., Praet, S. F. E., Skovgaard, D., Hansen, M., Aagaard, P., Kjær, Michael & Magnusson, Stig Peter, Aug 2014, In: Age (Dordrecht, Netherlands). 36, 4, p. 1-19 19 p., 9665.

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Published

    Myopati som årsag til akut opstået tetraparese på en intensivafdeling

    Lindqvist, J. K., Lauritzen, Martin, Laursen, H. & Benedek, K., 28 Jul 2014, In: Ugeskrift for Laeger. 176, 31, p. 2-3 2 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. Published

    Regulation of gene expression by the BLM helicase correlates with the presence of G-quadruplex DNA motifs

    Nguyen, G. H., Tang, W., Robles, A. I., Beyer, R. P., Gray, L. T., Welsh, J. A., Schetter, A. J., Kumamoto, K., Wang, X. W., Hickson, Ian David, Maizels, N., Monnat, R. J. & Harris, C. C., 8 Jul 2014, In: Proceedings of the National Academy of Sciences of the United States of America. 111, 27, p. 9905-10 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. Published

    The Dissolution of Double Holliday Junctions

    Bizard, A. H. & Hickson, Ian David, 1 Jul 2014, In: Cold Spring Harbor perspectives in biology. 6, p. 1-16 16 p., a016477.

    Research output: Contribution to journal › Review › Research › peer-review

  34. Published

    Functional implications of the p.Cys680Arg mutation in the MLH1 mismatch repair protein

    Dominguez-Valentin, M., Drost, M., Therkildsen, C., Rambech, E., Ehrencrona, H., Angleys, M., Lau Hansen, T., de Wind, N., Nilbert, Mef Christina & Rasmussen, Lene Juel, Jul 2014, In: Molecular Genetics & Genomic Medicine. 2, 4, p. 352-355 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. Published

    Multiscale vision model for event detection and reconstruction in two-photon imaging data

    Brazhe, A., Mathiesen, C., Lind, Barbara Lykke, Rubin, A. & Lauritzen, Martin, Jul 2014, In: Neurophotonics. 1, 1, 011012.

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    Eccentric exercise: acute and chronic effects on healthy and diseased tendons

    Kjær, Michael & Heinemeier, K. M., 1 Jun 2014, In: Journal of Applied Physiology. 116, 11, p. 1435-1438 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Published

    Mitochondria in biology and medicine--2012

    Desler, Claus & Rasmussen, Lene Juel, May 2014, In: Mitochondrion. 16, p. 2-6 5 p.

    Research output: Contribution to journal › Review › Research › peer-review

  38. Published

    Structure-specific endonucleases: guardians of fragile site stability

    Minocherhomji, S. & Hickson, Ian David, May 2014, In: Trends in Cell Biology. 24, 5, p. 321-327 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. Published

    The origins and processing of ultra fine anaphase DNA bridges

    Liu, Ying, Nielsen, Christian Friberg, Yao, Q. & Hickson, Ian David, 30 Apr 2014, In: Current Opinion in Genetics & Development. 26C, p. 1-5 5 p.

    Research output: Contribution to journal › Review › Research › peer-review

  40. Published

    The single-biopsy approach in determining protein synthesis in human slow-turning-over tissue: use of flood-primed, continuous infusion of amino acid tracer

    Holm, L., Reitelseder, S., Dideriksen, K., Nielsen, R. H., Bülow, J. & Kjær, Michael, 23 Apr 2014, In: American Journal of Physiology: Endocrinology and Metabolism. 306, 11, p. E1330-39 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. Published

    Assessing Genetic Variants of Uncertain Significance: The Example of Lynch Syndrome

    Rasmussen, Lene Juel & Heinen, C. D., 15 Apr 2014

    Research output: Other contribution › Net publication - Internet publication › Communication

  42. Published

    Aging impairs the recovery in mechanical muscle function following 4 days of disuse

    Hvid, L. G., Suetta, Charlotte, Nielsen, J., Jensen, M. M., Frandsen, U., Ørtenblad, N., Kjær, Michael & Aagaard, P., Apr 2014, In: Experimental Gerontology. 52, p. 1-8 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  43. Published

    Capillary pericytes regulate cerebral blood flow in health and disease

    Hall, C. N., Reynell, C., Gesslein, B., Hamilton, N. B., Mishra, A., Sutherland, B. A., O'Farrell, F. M., Buchan, A. M., Lauritzen, Martin & Attwell, D., Apr 2014, In: Nature. 508, 7494, p. 55-60 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Published

    Overexpression of DNA ligase III in mitochondria protects cells against oxidative stress and improves mitochondrial DNA base excision repair

    Akbari, M., Keijzers, G., Maynard, S., Scheibye-Knudsen, M., Desler, Claus, Hickson, Ian David & Bohr, Vilhelm, Apr 2014, In: DNA Repair. 16, p. 44-53 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  45. Published

    Differential satellite cell density of type I and II fibres with lifelong endurance running in old men

    Mackey, Abigail, Karlsen, Anders, Couppé, Christian, Mikkelsen, U. R., Nielsen, R. H., Magnusson, Stig Peter & Kjær, Michael, Mar 2014, In: Acta Physiologica (Print). 210, 3, p. 612-27 16 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  46. Published

    Structural and mechanistic insight into Holliday-junction dissolution by topoisomerase IIIα and RMI1

    Bocquet, N., Bizard, A. H., Abdulrahman, W., Larsen, N. B., Faty, M., Cavadini, S., Bunker, R. D., Kowalczykowski, S. C., Cejka, P., Hickson, Ian David & Thomä, N. H., Mar 2014, In: Nature Structural and Molecular Biology. 21, 3, p. 261-8 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. Published

    3-D ultrastructure and collagen composition of healthy and overloaded human tendon: evidence of tenocyte and matrix buckling

    Pingel, Jessica, Lu, Y., Starborg, T., Fredberg, U., Langberg, Henning, Nedergaard, A., Weis, M., Eyre, D., Kjær, Michael & Kadler, K. E., 9 Feb 2014, In: Journal of Anatomy. 224, 5, p. 548–555 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  48. Published

    Positive muscle protein net balance and differential regulation of atrogene expression after resistance exercise and milk protein supplementation

    Reitelseder, S., Agergaard, J., Doessing, S., Helmark, I. C., Schjerling, Peter, van Hall, Gerrit, Kjær, Michael & Holm, L., 1 Feb 2014, In: European Journal of Nutrition. 53, 1, p. 321-33 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  49. Published

    Application of a 5-tiered scheme for standardized classification of 2,360 unique mismatch repair gene variants in the InSiGHT locus-specific database

    Thompson, B. A., Spurdle, A. B., Plazzer, J-P., Greenblatt, M. S., Akagi, K., Al-Mulla, F., Bapat, B., Bernstein, I., Capellá, G., den Dunnen, J. T., du Sart, D., Fabre, A., Farrell, M. P., Farrington, S. M., Frayling, I. M., Frebourg, T., Goldgar, D. E., Heinen, C. D., Holinski-Feder, E., Kohonen-Corish, M. & 31 others, Robinson, K. L., Leung, S. Y., Martins, A., Moller, P., Morak, M., Nystrom, M., Peltomaki, P., Pineda, M., Qi, M., Ramesar, R., Rasmussen, Lene Juel, Royer-Pokora, B., Scott, R. J., Sijmons, R., Tavtigian, S. V., Tops, C. M., Weber, T., Wijnen, J., Woods, M. O., Macrae, F., Genuardi, M., Castillejo, A., Sexton, A., Chan, A. K. W., Viel, A., Blanco, A., French, A., Laner, A., Wagner, A., van den Ouweland, A. & on behalf of InSiGHT, O. B. O. I., Feb 2014, In: Nature Genetics. 46, 2, p. 107-115 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  50. Published

    Chronic alterations in growth hormone/insulin-like growth factor-I signaling lead to changes in mouse tendon structure

    Nielsen, R. H., Clausen, N. M., Schjerling, Peter, Larsen, J. O., Martinussen, Torben, List, E. O., Kopchick, J. J., Kjær, Michael & Heinemeier, K. M., Feb 2014, In: Matrix Biology. 34, p. 96-104 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  51. Published

    Increase in tendon protein synthesis in response to insulin-like growth factor-I is preserved in elderly men

    Nielsen, R. H., Holm, L., Malmgaard-Clausen, N. M., Reitelseder, S., Heinemeier, K. M. & Kjær, Michael, 1 Jan 2014, In: Journal of Applied Physiology. 116, 1, p. 42-6 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  52. Published

    Integrated measurements of electrical activity, Oxygen tension, Blood flow, And Ca2+-Signaling in rodents in vivo

    Mathiesen, C., Thomsen, Kirsten Joan & Lauritzen, Martin, 1 Jan 2014, Brain Energy Metabolism. Vol. 90. p. 243-264 22 p. (Neuromethods).

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

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