Damage and Repair

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  1. 2016
  2. Published

    Glutamate-system defects behind psychiatric manifestations in a familial hemiplegic migraine type 2 disease-mutation mouse model

    Bøttger, P., Glerup, S., Gesslein, B., Illarionova, N. B., Isaksen, T. J., Heuck, A., Clausen, B. H., Füchtbauer, E., Gramsbergen, J. B., Gunnarson, E., Aperia, A., Lauritzen, Martin, Lambertsen, K. L., Nissen, P. & Lykke-Hartmann, K., 25 Feb 2016, In: Scientific Reports. 6, 21 p., 22047.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    A new home for the Journal of Cerebral Blood Flow and Metabolism

    Dirnagl, U. & Lauritzen, Martin, Feb 2016, In: Journal of Cerebral Blood Flow and Metabolism. 36, 2, p. 277

    Research output: Contribution to journal › Editorial › Research › peer-review

  4. Published

    A short G1 phase imposes constitutive replication stress and fork remodelling in mouse embryonic stem cells

    Ahuja, A. K., Jodkowska, K., Teloni, F., Bizard, A. H., Zellweger, R., Herrador, R., Ortega, S., Hickson, Ian David, Altmeyer, M., Mendez, J. & Lopes, M., Feb 2016, In: Nature Communications. 7, 11 p., 10660.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Approaches to diagnose DNA mismatch repair gene defects in cancer

    Peña-Diaz, J. & Rasmussen, Lene Juel, Feb 2016, In: DNA Repair. 38, p. 147-154 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    TRAIP is a PCNA-binding ubiquitin ligase that protects genome stability after replication stress

    Hoffmann, Saskia, Smedegaard, S., Nakamura, K., Mortuza, G. B., Räschle, M., Ibañez de Opakua, A., Oka, Y., Feng, Y., Blanco, F. J., Mann, Matthias, Montoya, Guillermo, Groth, Anja, Bekker-Jensen, Simon Holst & Mailand, Niels, 4 Jan 2016, In: The Journal of Cell Biology. 212, 1, p. 63-75

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Human Achilles tendon glycation and function in diabetes

    Couppé, Christian, Svensson, R. B., Madsen, M. K., Kovanen, V., Grosset, J., Snorgaard, O., Bencke, J., Larsen, J. O., Bandholm, Thomas Quaade, Christensen, T. M., Boesen, A., Helmark, I. C., Aagaard, P., Kjær, Michael & Magnusson, Stig Peter, Jan 2016, In: Journal of Applied Physiology. 120, 2, p. 130-137 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Subjective sleep quality and daytime sleepiness in late midlife and their association with age-related changes in cognition

    Waller, K. L., Mortensen, Erik Lykke, Avlund, K., Osler, Merete, Fagerlund, Birgitte, Lauritzen, Martin & Jennum, Poul, Jan 2016, In: Sleep Medicine. 17, p. 165-73 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    The Journal of Cerebral Blood Flow and Metabolism clinical, inaugural issue

    Lauritzen, Martin & Dirnagl, U., Jan 2016, In: Journal of Cerebral Blood Flow and Metabolism. 36, 1, p. 3-3

    Research output: Contribution to journal › Editorial › Research

  10. Published

    'Spreading depression of Leão' and its emerging relevance to acute brain injury in humans

    Lauritzen, Martin & Strong, A. J., 2016, In: Journal of Cerebral Blood Flow and Metabolism. 37, 5, p. 1553-1570

    Research output: Contribution to journal › Review › Research › peer-review

  11. Published

    Collagen Homeostasis and Metabolism

    Magnusson, Stig Peter, Heinemeier, K. M. & Kjær, Michael, 2016, Metabolic Influences on Risk for Tendon Disorders. Springer, Vol. 920 . p. 11-25 15 p. (Advances in Experimental Medicine and Biology, Vol. 920).

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  12. Published

    Counteracting age-related loss of skeletal muscle mass: a clinical and ethnological trial on the role of protein supplementation and training load (CALM Intervention Study): study protocol for a randomized controlled trial

    Bechshøft, R., Reitelseder, S., Højfeldt, Grith Stougaard, Castro Mejia, J. L., Khakimov, Bekzod, Bin Ahmad, H. F., Kjær, Michael, Engelsen, Søren Balling, Laugesen, S. M. B., Rasmussen, Morten Arendt, Lassen, Aske Juul, Jensen, T., Beyer, N., Serena, A., Perez-Cueto, Federico J.A., Nielsen, Dennis Sandris, Jespersen, Astrid Pernille & Holm, L., 2016, In: Trials. 17, 17 p., 397.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Early detection of Alzheimer's disease using MRI hippocampal texture

    Sørensen, L., Igel, Christian, Hansen, N. L., Osler, Merete, Lauritzen, Martin, Rostrup, Egill & Nielsen, Mads, 2016, In: Human Brain Mapping. 37, 3, p. 1148-1161 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Elevated p16ink4a Expression in Human Labial Salivary Glands as a Potential Correlate of Cognitive Aging in Late Midlife

    Sørensen, Christiane Elisabeth, Tritsaris, Katerina, Reibel, Jesper, Lauritzen, Martin, Mortensen, Erik Lykke, Osler, Merete & Pedersen, Anne Marie Lynge, 2016, In: PloS one. 11, 3, p. e0152612

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Glia-Neuron Interactions in the Retina Can Be Studied in Cocultures of Muller Cells and Retinal Ganglion Cells

    Jensen, Dorte Skytt, Toft-Kehler, A. K., Braendstrup, C. T., Cejvanovic, S., Gurubaran, I. S., Bergersen, L. H. & Kolko, Miriam, 2016, In: Journal of Biomedicine and Biotechnology. 2016, 11 p., 1087647.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    LIFESTAT – Living with statins: An interdisciplinary project on the use of statins as a cholesterol-lowering treatment and for cardiovascular risk reduction

    Christensen, Christa Lykke, Helge, Jørn Wulff, Krasnik, Allan, Kriegbaum, Margit, Rasmussen, Lene Juel, Hickson, Ian David, Liisberg, Kasper Bering, Oxlund, Bjarke, Bruun, B., Lau, Sofie Rosenlund, Olsen, M. N. A., Andersen, John Sahl, Heltberg, Andreas Søndergaard, Kuhlman, A. C. B., Morville, T. H., Dohlmann, T. L., Larsen, Steen & Dela, Flemming, 2016, In: Scandinavian Journal of Public Health. 44, 5, p. 534-539 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Melatonin and cortisol profiles in late midlife and their association with age-related changes in cognition

    Waller, K. L., Mortensen, Erik Lykke, Avlund, K., Fagerlund, Birgitte, Lauritzen, Martin, Gammeltoft, S. & Jennum, Poul, 2016, In: Nature and Science of Sleep. 8, p. 47-53 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Methods of Assessing Human Tendon Metabolism and Tissue Properties in Response to Changes in Mechanical Loading

    Heinemeier, K. M., Kjær, Michael & Magnusson, Stig Peter, 2016, Metabolic Influences on Risk for Tendon Disorders: Pary 1. Springer, Vol. 920. p. 97-106 10 p. (Advances in Experimental Medicine and Biology).

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  19. Published

    Neurodegeneration in accelerated aging

    Scheibye-Knudsen, Morten, 2016, 190 p.

    Research output: Book/Report › Doctoral thesis › Research

  20. Published

    Rises in intracellular calcium in primary brain pericytes are caused by ATP

    Jensen, S. H., Helms, H. C. C., Cai, Changsi, Lauritzen, Martin, Waagepetersen, Helle S. & Larsen, Birger Brodin, 2016. 1 p.

    Research output: Contribution to conference › Conference abstract for conference › Research › peer-review

  21. Published

    SDCCAG8 Interacts with RAB Effector Proteins RABEP2 and ERC1 and Is Required for Hedgehog Signaling

    Airik, R., Schueler, M., Airik, M., Cho, J., Ulanowicz, K. A., Porath, J. D., Hurd, T. W., Bekker-Jensen, Simon Holst, Schrøder, J. M., Andersen, J. S. & Hildebrandt, F., 2016, In: P L o S One. 11, 5, 19 p., e0156081.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. 2015
  23. Published

    Replication stress activates DNA repair synthesis in mitosis

    Minocherhomji, S., Ying, S., Bjerregaard, Victoria Alexandra, Bursomanno, S., Aleliunaite, A., Wu, Wei, Mankouri, H. W., Shen, H., Liu, Ying & Hickson, Ian David, 10 Dec 2015, In: Nature. 528, 7581, p. 286-90 5 p.

    Research output: Contribution to journal › Letter › Research › peer-review

  24. Published

    Interaction of RECQ4 and MCM10 is important for efficient DNA replication origin firing in human cells

    Kliszczak, M., Sedlackova, H., Pitchai, G. P., Streicher, W. W., Krejci, L. & Hickson, Ian David, 1 Dec 2015, In: OncoTarget. 6, 38, p. 40464-79 16 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Matters of fiber size and myonuclear domain: does size matter more than age?

    Karlsen, Anders, Couppé, Christian, Andersen, J. L., Mikkelsen, U. R., Nielsen, R. H., Magnusson, Stig Peter, Kjær, Michael & Mackey, Abigail, Dec 2015, In: Muscle & Nerve. 52, 6, p. 1040-1046 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    p38- and MK2-dependent signalling promotes stress-induced centriolar satellite remodelling via 14-3-3-dependent sequestration of CEP131/AZI1

    Tollenaere, M. A. X., Villumsen, B. H., Blasius, M., Nielsen, J. C., Wagner, S. A., Bartek, J., Beli, P., Mailand, Niels & Bekker-Jensen, Simon Holst, 30 Nov 2015, In: Nature Communications. 6, p. 1-12 12 p., 10075.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    Histone H1 couples initiation and amplification of ubiquitin signalling after DNA damage

    Thorslund, T., Ripplinger, A., Hoffmann, Saskia, Wild, T., Uckelmann, M., Villumsen, B., Narita, Takeo, Sixma, T. K., Choudhary, Chunaram, Bekker-Jensen, Simon Holst & Mailand, Niels, 19 Nov 2015, In: Nature. 527, 7578, p. 389-93 5 p.

    Research output: Contribution to journal › Letter › Research › peer-review

  28. Published

    ATP induce an increase in intracellular Ca2+ in pericytes of the blood-brain barrier

    Jensen, S. H., Helms, H. C. C., Jessen, S. B., Lauritzen, Martin, Waagepetersen, Helle S. & Larsen, Birger Brodin, 2 Nov 2015.

    Research output: Contribution to conference › Poster › Research › peer-review

  29. Published

    Brain energy supply and metabolism in aging

    Lauritzen, Martin, Nov 2015, In: Acta Physiologica. 215, S705, p. 59-59 1 p., S18-1.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  30. Published

    Increased deoxythymidine triphosphate levels is a feature of relative cognitive decline

    Desler, Claus, Frederiksen, J. H., Olsen, M. N. A., Maynard, S., Keijzers, G., Fagerlund, Birgitte, Mortensen, Erik Lykke, Osler, Merete, Lauritzen, Martin, Bohr, Vilhelm & Rasmussen, Lene Juel, Nov 2015, In: Mitochondrion. 25, p. 34-7 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Published

    DNA Damage, DNA Repair, Aging, and Neurodegeneration

    Maynard, S., Fang, E. F., Scheibye-Knudsen, Morten, Croteau, D. L. & Bohr, Vilhelm, Oct 2015, In: Cold Spring Harbor Perspectives in Medicine. 5, 10, a025130.

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. Published

    Defective mitochondrial respiration, altered dNTP pools and reduced AP endonuclease 1 activity in peripheral blood mononuclear cells of Alzheimer's disease patients

    Maynard, S., Hejl, Anne-Mette, Dinh, T. T. S., Keijzers, G., Hansen, Åse Marie, Desler, Claus, Moreno-Villanueva, M., Bürkle, A., Rasmussen, Lene Juel, Waldemar, Gunhild & Bohr, Vilhelm, Oct 2015, In: Aging. 7, 10, p. 793-815 23 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. Published

    RNF138 joins the HR team

    Bekker-Jensen, Simon Holst & Mailand, Niels, Oct 2015, In: Nature Cell Biology. 17, 11, p. 1375-7 3 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Published

    A novel method for determining human ex vivo submaximal skeletal muscle mitochondrial function

    Hey-Mogensen, M., Gram, M., Jensen, M. B., Lund, M. T., Hansen, C. N., Scheibye-Knudsen, Morten, Bohr, Vilhelm & Dela, Flemming, 1 Sep 2015, In: The Journal of Physiology. 593, 17, p. 3991-4010 20 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. Published

    A Single Conserved Residue Mediates Binding of the Ribonucleotide Reductase Catalytic Subunit RRM1 to RRM2 and Is Essential for Mouse Development

    Specks, J., Lecona, E., Lopez-Contreras, Andres & Fernandez-Capetillo, O., Sep 2015, In: Molecular and Cellular Biology. 35, 17, p. 2910-2917 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    Impaired dynamics and function of mitochondria caused by mtDNA toxicity leads to heart failure

    Lauritzen, K. H., Kleppa, L., Aronsen, J. M., Eide, L., Carlsen, H., Haugen, O. P., Sjaastad, I., Klungland, A., Rasmussen, Lene Juel, Attramadal, H., Storm-Mathisen, J. & Bergersen, L. H., 1 Aug 2015, In: American Journal of Physiology: Heart and Circulatory Physiology. 309, 3, p. H434-H449 16 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Published

    Astrocytes gate synaptic transmission from unmyelinated sensory afferents

    Perrier, Jean-Francois Marie, Christensen, R. K., Delgado-Lezama, R., Russo, R., Lind, Barbara Lykke, Alcocer, E. L., Fabbiani, G., Schmitt, Nicole, Lauritzen, Martin, Petersen, A. V. & Carlsen, E. M., Aug 2015, In: Glia. 63, S1, p. E241-E241 T08-22B .

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  38. Published

    Exercise and Regulation of Bone and Collagen Tissue Biology

    Kjær, Michael, Jørgensen, N. R., Heinemeier, K. M. & Magnusson, Stig Peter, Aug 2015, Molecular and Cellular Regulation of Adaptation to Exercise. Vol. 135. p. 259-91 33 p. (Progress in Molecular Biology and Translational Science, Vol. 135).

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  39. Published

    Heavy Slow Resistance Versus Eccentric Training as Treatment for Achilles Tendinopathy: A Randomized Controlled Trial

    Beyer, R., Kongsgaard, M., Hougs Kjær, B., Øhlenschlæger, Tommy Frisgaard, Kjær, Michael & Magnusson, Stig Peter, Jul 2015, In: American Journal of Sports Medicine. 43, 7, p. 1704-11 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  40. Published

    Neuroglial Transmission

    Gundersen, V., Storm-Mathisen, J. & Bergersen, L. H., Jul 2015, In: Physiological Reviews. 95, 3, p. 695-726 32 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. Published

    Purinergic Signaling in Pericytes of the Blood-Brain Barrier

    Jensen, S. H., Helms, H. C. C., Jessen, S. B., Lauritzen, Martin, Waagepetersen, Helle S. & Larsen, Birger Brodin, Jul 2015.

    Research output: Contribution to conference › Poster › Research › peer-review

  42. Published

    Spreading Depression, Spreading Depolarizations, and the Cerebral Vasculature

    Ayata, C. & Lauritzen, Martin, Jul 2015, In: Physiological Reviews. 95, 3, p. 953-993 41 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  43. Published

    The lactate receptor, G-protein-coupled receptor 81/hydroxycarboxylic acid receptor 1: Expression and action in brain

    Morland, C., Lauritzen, K. H., Puchades, M., Holm-Hansen, S., Andersson, K., Gjedde, Albert, Attramadal, H., Storm-Mathisen, J. & Bergersen, L. H., Jul 2015, In: Journal of Neuroscience Research. 93, 7, p. 1045-1055 11 p.

    Research output: Contribution to journal › Review › Research › peer-review

  44. Published

    Lysyl oxidase activity is required for ordered collagen fibrillogenesis by tendon cells

    Herchenhan, A., Uhlenbrock, F. K., Eliasson, P., Weis, M., Eyre, D., Kadler, K. E., Magnusson, Stig Peter & Kjær, Michael, 26 Jun 2015, In: The Journal of Biological Chemistry. 290, 26, p. 16440-50 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  45. Published

    Ubiquitin-like protein UBL5 promotes the functional integrity of the Fanconi anemia pathway

    Oka, Y., Bekker-Jensen, Simon Holst & Mailand, Niels, 9 Apr 2015, In: E M B O Journal. 34, p. 1385-1398

    Research output: Contribution to journal › Journal article › Research › peer-review

  46. Published

    Increased Rrm2 gene dosage reduces fragile site breakage and prolongs survival of ATR mutant mice

    Lopez-Contreras, Andres, Specks, J., Barlow, J. H., Ambrogio, C., Desler, Claus, Vikingsson, S., Rodrigo-Perez, S., Green, H., Rasmussen, Lene Juel, Murga, M., Nussenzweig, A. & Fernandez-Capetillo, O., 1 Apr 2015, In: Genes & Development. 29, 7, p. 690-5 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. Published

    Lamin A/C-dependent interaction with 53BP1 promotes cellular responses to DNA damage

    Gibbs-Seymour, I., Markiewicz, E., Bekker-Jensen, Simon Holst, Mailand, Niels & Hutchison, C. J., Apr 2015, In: Aging Cell. 14, 2, p. 162-9 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  48. Published

    FBH1 Catalyzes Regression of Stalled Replication Forks

    Fugger, K., Mistrik, M., Neelsen, K. J., Yao, Q., Zellweger, R., Kousholt, A. N., Haahr, Peter Thorlund, Chu, W. K., Bartek, J., Lopes, M., Hickson, Ian David & Sørensen, Claus Storgaard, 10 Mar 2015, In: Cell Reports.

    Research output: Contribution to journal › Journal article › Research › peer-review

  49. Published

    The challenges of human population ageing

    Sander, M., Oxlund, Bjarke, Jespersen, Astrid Pernille, Krasnik, Allan, Mortensen, Erik Lykke, Westendorp, Rudi GJ & Rasmussen, Lene Juel, Mar 2015, In: Age and Ageing. 44, 2, p. 185-7 3 p.

    Research output: Contribution to journal › Journal article › Communication

  50. Published

    Insulin-like growth factor I enhances collagen synthesis in engineered human tendon tissue

    Herchenhan, A., Bayer, M. L., Eliasson, P., Magnusson, Stig Peter & Kjær, Michael, Feb 2015, In: Growth Hormone & I G F Research. 25, 1, p. 13-19 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  51. Published

    Lactate transport and signaling in the brain: Potential therapeutic targets and roles in body-brain interaction

    Bergersen, L. H., Feb 2015, In: Journal of Cerebral Blood Flow and Metabolism. 35, 2, p. 176-185 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  52. Published

    The human myotendinous junction: An ultrastructural and 3D analysis study

    Knudsen, A. B., Larsen, M., Mackey, Abigail, Hjort, M., Hansen, K. K., Qvortrup, Klaus, Kjær, Michael & Krogsgaard, Michael R., Feb 2015, In: Scandinavian Journal of Medicine & Science in Sports. 25, 1, p. E116-23

    Research output: Contribution to journal › Journal article › Research › peer-review

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