Damage and Repair

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  1. 2017
  2. Published

    Passive Double-Sensory Evoked Coherence Correlates with Long-Term Memory Capacity

    Horwitz, A., Mortensen, Erik Lykke, Osler, Merete, Fagerlund, Birgitte, Lauritzen, Martin & Benedek, K., 14 Dec 2017, In: Frontiers in Human Neuroscience. 11, 21 p., 598.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Handgrip strength shows no improvements in geriatric patients with persistent inflammation during hospitalization

    Norheim, K. L., Bautmans, I. & Kjær, Michael, 1 Dec 2017, In: Experimental Gerontology. 99, p. 115-119 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Bacterial infection increases risk of carcinogenesis by targeting mitochondria

    Strickertsson, J. A. B., Desler, Claus & Rasmussen, Lene Juel, Dec 2017, In: Seminars in Cancer Biology. 47, p. 95-100 6 p.

    Research output: Contribution to journal › Review › Research › peer-review

  5. Published

    Composition and adaptation of human myotendinous junction and neighboring muscle fibers to heavy resistance training

    Jakobsen, J. R., Mackey, Abigail, Knudsen, A. B., Kjær, Michael & Krogsgaard, Michael R., Dec 2017, In: Scandinavian Journal of Medicine & Science in Sports. 27, 12, p. 1547–1559

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Effects of anti-inflammatory (NSAID) treatment on human tendinopathic tissue

    Heinemeier, K. M., Øhlenschlæger, Tommy Frisgaard, Mikkelsen, U. R., Sønder, F., Schjerling, Peter, Svensson, R. B. & Kjær, Michael, Nov 2017, In: Journal of Applied Physiology. 123, 5, p. 1397-1405 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Monogenic diseases of DNA repair

    Keijzers, G., Bakula, Daniela Janina & Scheibye-Knudsen, Morten, Nov 2017, In: New England Journal of Medicine. 377, 19, p. 1868-1876 9 p.

    Research output: Contribution to journal › Review › Research › peer-review

  8. Published

    Early versus Delayed Rehabilitation after Acute Muscle Injury

    Bayer, M. L., Magnusson, Stig Peter, Kjær, Michael & Tendon Research Group Bispebjerg, T. R. G. B., 28 Sep 2017, In: The New England Journal of Medicine. 377, 13, p. 1300-1301 2 p.

    Research output: Contribution to journal › Comment/debate › Research

  9. Published

    Human DNA polymerase delta double-mutant D316A;E318A interferes with DNA mismatch repair in vitro

    Liu, D., Frederiksen, J. H., Liberti, S. E., Lützen, Anne Hoff Kjeldsen, Keijzers, G., Pena-Diaz, J. & Rasmussen, Lene Juel, 19 Sep 2017, In: Nucleic Acids Research. 45, 16, p. 9427-9440 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    In hip osteoarthritis, Nordic Walking is superior to strength training and home based exercise for improving function

    Bieler, T., Siersma, Volkert Dirk, Magnusson, Stig Peter, Kjær, Michael, Christensen, H. E. & Beyer, N., Aug 2017, In: Scandinavian Journal of Medicine & Science in Sports. 27, 8, p. 873–886 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Skeletal muscle morphology, protein synthesis and gene expression in Ehlers Danlos Syndrome

    Nygaard, R. H., Jensen, J. K., Voermans, N. C., Heinemeier, K. M., Schjerling, Peter, Holm, L., Agergaard, J., Mackey, Abigail, Andersen, J. L., Remvig, L. & Kjær, Michael, Aug 2017, In: Journal of Applied Physiology. 123, 2, p. 482-488

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    DNA mismatch repair and its many roles in eukaryotic cells

    Liu, D., Keijzers, G. & Rasmussen, Lene Juel, Jul 2017, In: Mutation Research - Reviews in Mutation Research. 773, p. 174-187 14 p.

    Research output: Contribution to journal › Review › Research › peer-review

  13. Published

    Skeletal muscle morphology and regulatory signalling in endurance-trained and sedentary individuals: The influence of ageing

    Mikkelsen, U. R., Agergaard, J., Couppé, Christian, Grosset, J. F., Karlsen, Anders, Magnusson, Stig Peter, Schjerling, Peter, Kjær, Michael & Mackey, Abigail, Jul 2017, In: Experimental Gerontology. 93, p. 54-67

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    RECQ5 Helicase Cooperates with MUS81 Endonuclease in Processing Stalled Replication Forks at Common Fragile Sites during Mitosis

    Di Marco, S., Hasanova, Z., Kanagaraj, R., Chappidi, N., Altmannova, V., Menon, S., Sedlackova, H., Langhoff, J., Surendranath, K., Hühn, D., Bhowmick, Rahul, Marini, V., Ferrari, S., Hickson, Ian David, Krejci, L. & Janscak, P., 1 Jun 2017, In: Molecular Cell. 66, 5, p. 658-671.e8

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    A simple DNA recombination screening method by RT-PCR as an alternative to Southern blot

    Albers, E., Sbroggiò, M., Martin Gonzalez, Javier, Avram, Alexandra Ioana, Munk, S. & Lopez-Contreras, Andres, Jun 2017, In: Transgenic Research. 26, 3, p. 429-434 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Inflammation relates to resistance training-induced hypertrophy in elderly patients

    Norheim, K. L., Cullum, C. K., Andersen, J. L., Kjær, Michael & Karlsen, Anders, Jun 2017, In: Medicine and Science in Sports and Exercise. 49, 6, p. 1079-1085 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    The lactate receptor HCAR1 promotes neuronal development and protects axons and myelin during hypoglycemia

    Kennedy, L. H., Andersson, K. A., Haugen, O. P., Puchades, M. A., Storm-Mathisen, J., Morland, C., Bergersen, L. H. & Rinholm, J. E., Jun 2017, In: Glia. 65, S1, p. E152-E153 T03-024B.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  18. Published

    Recording, analysis, and interpretation of spreading depolarizations in neurointensive care: Review and recommendations of the COSBID research group

    Dreier, J. P., Fabricius, M., Ayata, C., Sakowitz, O. W., William Shuttleworth, C., Dohmen, C., Graf, R., Vajkoczy, P., Helbok, R., Suzuki, M., Schiefecker, A. J., Major, S., Winkler, M. K., Kang, E-J., Milakara, D., Oliveira-Ferreira, A. I., Reiffurth, C., Revankar, G. S., Sugimoto, K., Dengler, N. F. & 70 others, Hecht, N., Foreman, B., Feyen, B., Kondziella, Daniel, Friberg, C. K., Piilgaard, H., Rosenthal, E. S., Westover, M. B., Maslarova, A., Santos, E., Hertle, D., Sánchez-Porras, R., Jewell, S. L., Balança, B., Platz, J., Hinzman, J. M., Lückl, J., Schoknecht, K., Schöll, M., Drenckhahn, C., Feuerstein, D., Eriksen, N., Horst, V., Bretz, J. S., Jahnke, P., Scheel, M., Bohner, G., Rostrup, E., Pakkenberg, B., Heinemann, U., Claassen, J., Carlson, A. P., Kowoll, C. M., Lublinsky, S., Chassidim, Y., Shelef, I., Friedman, A., Brinker, G., Reiner, M., Kirov, S. A., Andrew, R. D., Farkas, E., Güresir, E., Vatter, H., Chung, L. S., Brennan, K. C., Lieutaud, T., Marinesco, S., Maas, A. I., Sahuquillo, J., Dahlem, M. A., Richter, F., Herreras, O., Boutelle, M. G., Okonkwo, D. O., Bullock, M. R., Witte, O. W., Martus, P., van den Maagdenberg, A. M., Ferrari, M. D., Dijkhuizen, R. M., Shutter, L. A., Andaluz, N., Schulte, A. P., MacVicar, B., Watanabe, T., Woitzik, J., Lauritzen, Martin, Strong, A. J. & Hartings, J. A., May 2017, In: Journal of Cerebral Blood Flow and Metabolism. 37, 5, p. 1595-1625 31 p.

    Research output: Contribution to journal › Review › Research › peer-review

  19. Published

    Predicting the impact of Lynch syndrome-causing missense mutations from structural calculations

    Nielsen, S. V., Stein, Amelie, Dinitzen, A. B., Papaleo, E., Tatham, M. H., Poulsen, E. G., Kassem, M. M., Rasmussen, Lene Juel, Lindorff-Larsen, Kresten & Hartmann-Petersen, Rasmus, 19 Apr 2017, In: PLoS Genetics. 13, 4, 26 p., e1006739.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Characterising the proximal patellar tendon attachment and its relationship to skeletal maturity in adolescent ballet dancers

    Rudavsky, A., Cook, J., Magnusson, Stig Peter, Kjær, Michael & Docking, S., Apr 2017, In: Muscles, Ligaments and Tendons Journal. 7, 2, p. 306-314 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Correction for non-rigid movement artefacts in calcium imaging using local-global optical flow and PCA-based templates

    Brazhe, A., Fordsmann, J. & Lauritzen, Martin, Apr 2017, In: Journal of Cerebral Blood Flow and Metabolism. 37, S1, p. 360-361 PS04-077.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  22. Published

    The Effect of Aging and Mechanical Loading on the Metabolism of Articular Cartilage

    Jørgensen, A. E. M., Kjær, Michael & Heinemeier, K. M., Apr 2017, In: Journal of Rheumatology. 44, 4, p. 410-417

    Research output: Contribution to journal › Review › Research › peer-review

  23. Published

    An advanced glycation endproduct (AGE)-rich diet promotes accumulation of AGEs in Achilles tendon

    Skovgaard, D., Svensson, R. B., Scheijen, J., Eliasson, P., Mogensen, P., Hag, Anne Mette Fisker, Kjær, Michael, Schalkwijk, C. G., Schjerling, P., Magnusson, Stig Peter & Couppé, C., Mar 2017, In: Physiological Reports. 5, 6, 7 p., e13215.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Connective tissue regeneration in skeletal muscle after eccentric contraction-induced injury

    Mackey, Abigail & Kjær, Michael, Mar 2017, In: Journal of Applied Physiology. 122, 3, p. 533-540 8 p.

    Research output: Contribution to journal › Review › Research › peer-review

  25. Published

    Nanomaterial-induced cell death in pulmonary and hepatic cells following exposure to three different metallic materials: The role of autophagy and apoptosis

    Kermanizadeh, A., Jantzen, K., Ward, M. B., Durhuus, J. A., Rasmussen, Lene Juel, Loft, Steffen & Møller, Peter, Mar 2017, In: Nanotoxicology. 11, 2, p. 184-200 17 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    Tendon collagen synthesis declines with immobilization in elderly humans: no effect of anti-inflammatory medication

    Dideriksen, K., Boesen, A. P., Reitelseder, S., Couppé, C., Svensson, R., Schjerling, P., Magnusson, Stig Peter, Holm, L. & Kjær, Michael, Feb 2017, In: Journal of Applied Physiology. 122, 2, p. 273-282 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    EXO1 (Exonuclease 1)

    Rasmussen, Lene Juel & Keijzers, G., 5 Jan 2017, Encyclopedia of Signaling Molecules . Choi, S. (ed.). New York: Springer, 7 p.

    Research output: Chapter in Book/Report/Conference proceeding › Encyclopedia chapter › Research

  28. Published

    Quantification of cell density in rat Achilles tendon: development and application of a new method

    Couppé, C., Svensson, R. B., Heinemeier, K. M., Thomsen, E. W., Bayer, M. L., Christensen, L., Kjær, Michael, Magnusson, Stig Peter & Schjerling, P., Jan 2017, In: Histochemistry and Cell Biology. 147, 1, p. 97-102 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    A critical role for astrocytes in hypercapnic vasodilation in brain

    Howarth, C., Sutherland, B. A., Choi, H. B., Martin, C., Lind, Barbara Lykke, Khennouf, Lila, LeDue, J. M., Pakan, J. M. P., Ko, R. W., Ellis-Davies, G. C. R., Lauritzen, Martin, Sibson, N. R., Buchan, A. M. & MacVicar, B. A., 2017, In: The Journal of Neuroscience. 37, 9, p. 2403-2414 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    A novel TPR-BEN domain interaction mediates PICH-BEND3 association

    Pitchai, G. P., Kaulich, M., Bizard, A. H., Mesa, Pablo, Yao, Q., Sarlos, K., Streicher, W. W., Nigg, E. A., Montoya, Guillermo & Hickson, Ian David, 2017, In: Nucleic Acids Research. 19, 2, p. 11413–11424

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Published

    Acute inactivation of the replicative helicase in human cells triggers MCM8-9-dependent DNA synthesis

    Natsume, T., Nishimura, K., Minocherhomji, S., Bhowmick, Rahul, Hickson, Ian David & Kanemaki, M. T., 2017, In: Genes & Development. 31, 8, p. 816-829 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. Published

    Biochemical and Mass Spectrometry-Based Approaches to Profile SUMOylation in Human Cells

    Kessler, B. M., Bursomanno, S., McGouran, J. F., Hickson, Ian David & Liu, Ying, 2017, Activity-Based Proteomics: Methods and Protocols. Overkleeft, H. S. & Florea, B. I. (eds.). Humana Press, Vol. 1491. p. 131-144 14 p. (Methods in Molecular Biology, Vol. 1491).

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  33. Published

    Bioenergetic Changes during Differentiation of Human Embryonic Stem Cells along the Hepatic Lineage

    Hopkinson, B. M., Desler, Claus, Kalisz, M., Vestentoft, P. S., Rasmussen, Lene Juel & Bisgaard, Hanne Cathrine, 2017, In: Oxidative Medicine and Cellular Longevity. 2017, 11 p., 5080128.

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Published

    Cockayne syndrome: Clinical features, model systems and pathways

    Karikkineth, A. C., Scheibye-Knudsen, Morten, Fivenson, E., Croteau, D. L. & Bohr, Vilhelm, 2017, In: Ageing Research Reviews. 33, p. 3-17

    Research output: Contribution to journal › Review › Research › peer-review

  35. Published

    Disturbed mitochondrial function restricts glutamate uptake in the human Müller glia cell line, MIO-M1

    Vohra, Rupali, Gurubaran, I. S., Henriksen, U., Bergersen, L. H., Rasmussen, Lene Juel, Desler, C., Jensen, Dorte Skytt & Kolko, Miriam, 2017, In: Mitochondrion. 36, p. 52-59

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    Exercise induces cerebral VEGF and angiogenesis via the lactate receptor HCAR1

    Morland, C., Andersson, K. A., Haugen, O. P., Hadzic, A., Kleppa, L., Gille, A., Rinholm, J. E., Palibrk, V., Diget, E. H., Kennedy, L. H., Stolen, T., Hennestad, E., Moldestad, O., Cai, Y., Puchades, M., Offermanns, S., Vervaeke, K., Bjoras, M., Wisloff, U., Storm-Mathisen, J. & 1 others, Bergersen, L. H., 2017, In: Nature Communications. 8, 9 p., 15557.

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Published

    Genomic and functional integrity of the hematopoietic system requires tolerance of oxidative DNA lesions

    Martín-Pardillos, A., Tsaalbi-Shtylik, A., Chen, S., Lazare, S., Van Os, R. P., Dethmers-Ausema, A., Fakouri, N. B., Bosshard, M., Aprigliano, R., Van Loon, B., Salvatori, D. C. F., Hashimoto, K., Van Der Spek, C. D., Moriya, M., Rasmussen, Lene Juel, De Haan, G., Raaijmakers, M. H. G. P. & De Wind, N., 2017, In: Blood. 130, 13, p. 1523-1534 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. Published

    Human skeletal muscle fibroblasts stimulate in vitro myogenesis and in vivo muscle regeneration

    Mackey, Abigail, Magnan, M., Chazaud, B. & Kjær, Michael, 2017, In: The Journal of Physiology. 595, 15, p. 5115-5127 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. Published

    Impact of GH administration on athletic performance in healthy young adults: A systematic review and meta-analysis of placebo-controlled trials

    Hermansen, K., Bengtsen, M., Kjær, Michael, Vestergaard, P. & Jørgensen, J. O. L., 2017, In: Growth Hormone & I G F Research. 34, p. 38-44

    Research output: Contribution to journal › Review › Research › peer-review

  40. Published

    Improved Functional Performance in Geriatric Patients During Hospital Stay

    Karlsen, Anders, Loeb, M. R., Andersen, K. B., Joergensen, K. J., Scheel, F. U., Turtumoeygard, I. F., Perez, A. L. R., Kjær, Michael & Beyer, N., 2017, In: American Journal of Physical Medicine and Rehabilitation. 96, 5, p. e78-e84

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. Published

    Improved skeletal muscle mass and strength after heavy strength training in very old individuals

    Bechshøft, R. L., Malmgaard-Clausen, N. M., Gliese, B., Beyer, N., Mackey, Abigail, Andersen, J. L., Kjær, Michael & Holm, L., 2017, In: Experimental Gerontology. 92, p. 96-105 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. Published

    Interneuron Deficit Associates Attenuated Network Synchronization to Mismatch of Energy Supply and Demand in Aging Mouse Brains

    Jessen, S. B., Mathiesen, C., Lind, Barbara Lykke & Lauritzen, Martin, 2017, In: Cerebral Cortex. 27, 1, p. 646-659

    Research output: Contribution to journal › Journal article › Research › peer-review

  43. Published

    Involvement of the DNA mismatch repair system in cisplatin sensitivity of testicular germ cell tumours

    Rudolph, C., Melau, C., Nielsen, J. E., Jensen, K. V., Liu, D., Pena-Diaz, J., Meyts, E. R., Rasmussen, Lene Juel & Jorgensen, A., 2017, In: Cellular Oncology. 40, 4, p. 341-355

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Published

    Knotty Problems during Mitosis: Mechanistic Insight into the Processing of Ultrafine DNA Bridges in Anaphase

    Sarlós, K., Biebricher, A., Petermann, E. J. G., Wuite, G. J. L. & Hickson, Ian David, 2017, In: Cold Spring Harbor Laboratory. Symposia on Quantitative Biology. 82, p. 187-195

    Research output: Contribution to journal › Journal article › Research › peer-review

  45. Published

    Mitophagy in neurodegeneration and aging

    Fivenson, E. M., Lautrup, S., Sun, N., Scheibye-Knudsen, Morten, Stevnsner, T., Nilsen, H., Bohr, Vilhelm & Fang, E. F., 2017, In: Neurochemistry International. 109, p. 202-209

    Research output: Contribution to journal › Review › Research › peer-review

  46. Published

    Multi-modal assessment of neurovascular coupling during cerebral ischaemia and reperfusion using remote middle cerebral artery occlusion

    Sutherland, B. A., Fordsmann, J. C., Martin, C., Neuhaus, A. A., Witgen, B. M., Hansen, H. P., Lønstrup, M., Couch, Y., Sibson, N. R., Lauritzen, Martin & Buchan, A. M., 2017, In: Journal of Cerebral Blood Flow and Metabolism. 37, 7, p. 2494-2508 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. Published

    Muscle power is an important measure to detect deficits in muscle function in hip osteoarthritis: a cross-sectional study

    Bieler, T., Magnusson, Stig Peter, Christensen, H. E., Kjær, Michael & Beyer, N., 2017, In: Disability and Rehabilitation. 39, 14, p. 1414-1421

    Research output: Contribution to journal › Journal article › Research › peer-review

  48. Published

    Myosin content of single muscle fibers following short-term disuse and active recovery in young and old healthy men

    Hvid, L. G., Brocca, L., Ørtenblad, N., Suetta, Charlotte, Aagaard, P., Kjær, Michael, Bottinelli, R. & Pellegrino, M. A., 2017, In: Experimental Gerontology. 87, Part A, p. 100-107

    Research output: Contribution to journal › Journal article › Research › peer-review

  49. Published

    No Change in Lower Limb Extension Power during a Hospital Stay in Geriatric Patients, Despite Improved Functional Level

    Karlsen, Anders, Loeb, M. R., Turtumoeygard, I. F., Scheel, F. U., Andersen, K. B., Joergensen, K. J., Rodriguez Perez, A. L., Kjær, Michael & Beyer, N., 2017, In: Annals of Gerontology and Geriatric Research . 4, 1, 7 p., 1046.

    Research output: Contribution to journal › Journal article › Research › peer-review

  50. Published

    PSD-95 uncoupling from NMDA receptors by Tat-N-dimer ameliorates neuronal depolarization in cortical spreading depression

    Kucharz, Krzysztof, Søndergaard Rasmussen, I., Bach, Anders, Strømgaard, Kristian & Lauritzen, Martin, 2017, In: Journal of Cerebral Blood Flow and Metabolism. 37, 5, p. 1820-1828

    Research output: Contribution to journal › Journal article › Research › peer-review

  51. Published

    Potential biomarkers of DNA replication stress in cancer

    Ren, L., Chen, L., Wu, Wei, Garribba, L., Tian, H., Liu, Z., Vogel, Ivan, Li, C., Hickson, Ian David & Liu, Ying, 2017, In: OncoTarget. 8, 23, p. 36996-37008 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

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