Damage and Repair

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  1. Published

    Effects of resistance training on endurance capacity and muscle fiber composition in young top-level cyclists

    Aagaard, P., Andersen, J. L., Bennekou, M., Larsson, B., Olesen, J. L., Crameri, R., Magnusson, S. P. & Kjær, Michael, 2011, In: Scandinavian Journal of Medicine & Science in Sports. 21, 6, p. e298-307

    Research output: Contribution to journal › Journal article › Research › peer-review

  2. Published

    UTE T2* mapping of tendinopathic patellar tendons: an MRI reproducibility study

    Agergaard, A. S., Malmgaard-Clausen, N. M., Svensson, R. B., Nybing, J. D., Boesen, Mikael Ploug, Kjær, Michael, Magnusson, Stig Peter & Hansen, P., 2021, In: Acta Radiologica. 62, 2, p. 215-224 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Mechanical properties and UTE-T2* in Patellar tendinopathy: The effect of load magnitude in exercise-based treatment

    Agergaard, A. S., Svensson, R. B., Høffner, Rikke, Hansen, P., Couppé, Christian, Kjær, Michael & Magnusson, Stig Peter, 2021, In: Scandinavian Journal of Medicine and Science in Sports. 31, 10, p. 1981-1990

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    How Do We Explore Heterogeneity in Turnover of Musculoskeletal Proteins?

    Agergaard, J. & Kjær, Michael, 2021, In: Function. 2, 4, 2 p., 034.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Myogenic, matrix and growth factor mRNA expression in human skeletal muscle: effect of contraction intensity and feeding

    Agergaard, J., Reitelseder, S., Pedersen, T. G., Doessing, S., Schjerling, P., Langberg, Henning, Miller, B. F., Aagaard, P., Kjær, Michael & Holm, L., 20 Mar 2013, In: Muscle & Nerve. 47, 5, p. 748-759 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    A short G1 phase imposes constitutive replication stress and fork remodelling in mouse embryonic stem cells

    Ahuja, A. K., Jodkowska, K., Teloni, F., Bizard, A. H., Zellweger, R., Herrador, R., Ortega, S., Hickson, Ian David, Altmeyer, M., Mendez, J. & Lopes, M., Feb 2016, In: Nature Communications. 7, 11 p., 10660.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    SDCCAG8 Interacts with RAB Effector Proteins RABEP2 and ERC1 and Is Required for Hedgehog Signaling

    Airik, R., Schueler, M., Airik, M., Cho, J., Ulanowicz, K. A., Porath, J. D., Hurd, T. W., Bekker-Jensen, Simon Holst, Schrøder, J. M., Andersen, J. S. & Hildebrandt, F., 2016, In: P L o S One. 11, 5, 19 p., e0156081.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Renal-Retinal Ciliopathy Gene Sdccag8 Regulates DNA Damage Response Signaling

    Airik, R., Slaats, G. G., Guo, Z., Weiss, A., Khan, N., Ghosh, A., Hurd, T. W., Bekker-Jensen, Simon Holst, Schrøder, J. M., Elledge, S. J., Andersen, J. S., Kispert, A., Castelli, M., Boletta, A., Giles, R. H. & Hildebrandt, F., Nov 2014, In: Journal of the American Society of Nephrology:JASN. 25, 11, p. 2573-83 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Cytosolic self-DNA—A potential source of chronic inflammation in aging

    Akbari, M., Shanley, D. P., Bohr, Vilhelm & Rasmussen, Lene Juel, 2021, In: Cells. 10, 12, 3544.

    Research output: Contribution to journal › Review › Research › peer-review

  10. Published

    Overexpression of DNA ligase III in mitochondria protects cells against oxidative stress and improves mitochondrial DNA base excision repair

    Akbari, M., Keijzers, G., Maynard, S., Scheibye-Knudsen, M., Desler, Claus, Hickson, Ian David & Bohr, Vilhelm, Apr 2014, In: DNA Repair. 16, p. 44-53 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Integrated method for quantitative morphometry and oxygen transport modeling in striated muscle

    Al-Shammari, A. A., Kissane, R. W. P., Holbek, S., Mackey, Abigail, Andersen, T. R., Gaffney, E. A., Kjær, Michael & Egginton, S., 2019, In: Journal of Applied Physiology. 126, 3, p. 544-557 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Supraphysiological protection from replication stress does not extend mammalian lifespan

    Albers, E., Avram, Alexandra Ioana, Sbroggio, M., Fernandez-Capetillo, O. & Lopez-Contreras, Andres, 2020, In: Aging. 12, 7, p. 5612-5624 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    A simple DNA recombination screening method by RT-PCR as an alternative to Southern blot

    Albers, E., Sbroggiò, M., Martin Gonzalez, Javier, Avram, Alexandra Ioana, Munk, S. & Lopez-Contreras, Andres, Jun 2017, In: Transgenic Research. 26, 3, p. 429-434 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Loss of PICH Results in Chromosomal Instability, p53 Activation, and Embryonic Lethality

    Albers, E., Sbroggiò, M., Pladevall Morera, David, Bizard, A. H., Avram, Alexandra Ioana, Gonzalez, P., Martin Gonzalez, Javier, Hickson, Ian David & Lopez-Contreras, Andres, 2018, In: Cell Reports. 24, 12, p. 3274-3284 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    The NAD+-mitophagy axis in healthy longevity and in artificial intelligence-based clinical applications

    Aman, Y., Frank, J., Lautrup, S. H., Matysek, A., Niu, Z., Yang, G., Shi, L., Bergersen, L. H., Storm-Mathisen, J., Rasmussen, Lene Juel, Bohr, Vilhelm, Nilsen, H. & Fang, E. F., 2020, In: Mechanisms of Ageing and Development. 185, 111194.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Effects of intensive physical rehabilitation on neuromuscular adaptations in adults with poststroke hemiparesis

    Andersen, L. L., Zeeman, P., Jørgensen, J. R., Bech-Pedersen, D. T., Sørensen, J. G., Kjær, Michael & Andersen, J. L., 2011, In: Journal of Strength and Conditioning Research. 25, 10, p. 2808-17 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Effect of contrasting physical exercise interventions on rapid force capacity of chronically painful muscles

    Andersen, L. L., Andersen, J. L., Suetta, Charlotte, Kjær, Michael, Søgaard, K. & Sjøgaard, G., 2009, In: Journal of Applied Physiology. 107, 5, p. 1413-9 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    14-3-3 checkpoint regulatory proteins interact specifically with DNA repair protein human exonuclease 1 (hEXO1) via a semi-conserved motif

    Andersen, S. D., Keijzers, G., Rampakakis, E., Engels, K., Luhn, P., El-Shemerly, M., Nielsen, Finn Cilius, Du, Y., May, A., Bohr, Vilhelm, Ferrari, S., Zannis-Hadjopoulos, M., Fu, H. & Rasmussen, Lene Juel, Mar 2012, In: D N A Repair. 11, 3, p. 267-77 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Functional characterization of MLH1 missense variants identified in Lynch Syndrome patients

    Andersen, S. D., Liberti, S. E., Lützen, A., Drost, M., Bernstein, I., Nilbert, Mef Christina, Dominguez, M., Nyström, M., Hansen, Thomas van Overeem, Christoffersen, J. W., Jäger, A. C., de Wind, N., Nielsen, Finn Cilius, Tørring, P. M. & Rasmussen, Lene Juel, Dec 2012, In: Human Mutation. 33, 12, p. 1647-1655 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    RANKL regulates testicular cancer growth and Denosumab treatment has suppressive effects on GCNIS and advanced seminoma

    Andreassen, C. H., Lorenzen, M., Nielsen, J. E., Kafai Yahyavi, S., Toft, Birgitte Grønkær, Ingerslev, L. R., Clemmensen, Christoffer, Rasmussen, Lene Juel, Bokemeyer, C., Juul, Anders, Jørgensen, A. & Jensen, M. B., 2022, In: British Journal of Cancer. 127, p. 408-421

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    A defined human aging phenome

    Andreassen, Søren Norge, Ben Ezra, Michael & Scheibye-Knudsen, Morten, 2019, In: Aging. 11, 15, p. 5786-5806 21 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Rev1 deficiency induces a metabolic shift in MEFs that can be manipulated by the NAD+ precursor nicotinamide riboside

    Anugula, Sharath, Li, Zhiquan, Li, Yuan, Hendriksen, A., Christensen, P. B., Wang, L., Monk, J. M., de Wind, N., Bohr, Vilhelm, Desler, Claus, Naviaux, R. K. & Rasmussen, Lene Juel, 2023, In: Heliyon. 9, 6, e17392.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Yeast as a model system to study RecQ helicase function

    Ashton, T. M. & Hickson, Ian David, 2010, In: DNA Repair. 9, 3, p. 303-14 11 p.

    Research output: Contribution to journal › Review › Research › peer-review

  24. Published

    Pathways for Holliday Junction Processing during Homologous Recombination in Saccharomyces cerevisiae

    Ashton, T. M., Mankouri, H. W., Heidenblut, A., McHugh, P. J. & Hickson, Ian David, 1 May 2011, In: Molecular and Cellular Biology. 31, 9, p. 1921-33 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    ATR expands embryonic stem cell fate potential in response to replication stress

    Atashpaz, S., Samadi Shams, S., Martin Gonzalez, Javier, Sebestyén, E., Arghavanifard, N., Gnocchi, A., Albers, E., Minardi, S., Faga, G., Soffientini, P., Allievi, E., Cancila, V., Bachi, A., Fernández-Capetillo, Ó., Tripodo, C., Ferrari, F., Lopez-Contreras, Andres & Costanzo, V., 2020, In: eLife. 9, e54756.

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    Spreading Depression, Spreading Depolarizations, and the Cerebral Vasculature

    Ayata, C. & Lauritzen, Martin, Jul 2015, In: Physiological Reviews. 95, 3, p. 953-993 41 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    High Intensity Interval Training Ameliorates Mitochondrial Dysfunction in the Left Ventricle of Mice with Type 2 Diabetes

    Baekkerud, F. H., Salerno, S., Ceriotti, P., Morland, C., Storm-Mathisen, J., Bergersen, L. H., Hoydal, M. A., Catalucci, D. & Stolen, T. O., 2019, In: Cardiovascular Toxicology. 19, 5, p. 422-431 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    Latest advances in aging research and drug discovery

    Bakula, D., Ablasser, A., Aguzzi, A., Antebi, A., Barzilai, N., Bittner, M. I., Jensen, M. B., Calkhoven, C. F., Chen, D., de Grey, A. D. N. J., Feige, J. N., Georgievskaya, A., Gladyshev, V. N., Golato, T., Gudkov, A. V., Hoppe, T., Kaeberlein, M., Katajisto, P., Kennedy, B. K., Lal, U. & 10 others, Martin-Villalba, A., Moskalev, A. A., Ozerov, I., Petr, Michael Angelo, Reason, Rubinsztein, D. C., Tyshkovskiy, A., Vanhaelen, Q., Zhavoronkov, A. & Scheibye-Knudsen, Morten, 2019, In: Aging. 11, 22, p. 9971-9981 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    Aging and drug discovery

    Bakula, D., Aliper, A. M., Mamoshina, P., Petr, M. A., Teklu, A., Baur, J. A., Campisi, J., Ewald, C. Y., Georgievskaya, A., Gladyshev, V. N., Kovalchuk, O., Lamming, D. W., Luijsterburg, M. S., Martín-Montalvo, A., Maudsley, S., Mkrtchyan, G. V., Moskalev, A., Jay Olshansky, S., Ozerov, I. V., Pickett, A. & 3 others, Ristow, M., Zhavoronkov, A. & Scheibye-Knudsen, Morten, 2018, In: Aging. 10, 11, p. 3079-3088 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    MitophAging: Mitophagy in Aging and Disease

    Bakula, Daniela Janina & Scheibye-Knudsen, Morten, 2020, In: Frontiers in Cell and Developmental Biology. 8, 16 p., 239.

    Research output: Contribution to journal › Review › Research › peer-review

  31. Published

    Duplex DNA and BLM regulate gate opening by the human TopoIIIα-RMI1-RMI2 complex

    Bakx, J. A. M., Biebricher, A. S., King, G. A., Christodoulis, P., Sarlós, K., Bizard, A. H., Hickson, Ian David, Wuite, G. J. L. & Peterman, E. J. G., 2022, In: Nature Communications. 13, 1, 584.

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. Published

    Copenhagen Consensus statement 2019: Physical activity and ageing

    Bangsbo, J., Blackwell, J., Boraxbekk, C-J., Caserotti, P., Dela, F., Evans, A. B., Jespersen, A. P., Gliemann, L., Kramer, A. F., Lundbye-Jensen, J., Mortensen, E. L., Lassen, A. J., Gow, A. J., Harridge, S. D. R., Hellsten, Y., Kjær, M., Kujala, U. M., Rhodes, R. E., Pike, E. C. J., Skinner, T. & 6 others, Skovgaard, T., Troelsen, J., Tulle, E., Tully, M. A., van Uffelen, J. G. Z. & Viña, J., 2019, In: British Journal of Sports Medicine. 53, 14, p. 856-858 3 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. Published

    Bengt Saltin (1935-2014)

    Bangsbo, Jens, Kjær, Michael & Hellsten, Ylva, 2014, In: Journal of Physiology. 592, 23, p. 5149-5151 3 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Published

    Muscle-strain injury exudate favors acute tissue healing and prolonged connective tissue formation in humans

    Bayer, M. L., Bang, L., Hoegberget-Kalisz, M., Svensson, R. B., Olesen, J. L., Karlsson, M. M., Schjerling, Peter, Hellsten, Ylva, Høier, B., Magnusson, Stig Peter & Kjær, Michael, 2019, In: F A S E B Journal. 33, 9, p. 10369-10382 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. Published

    Early versus Delayed Rehabilitation after Acute Muscle Injury

    Bayer, M. L., Magnusson, Stig Peter, Kjær, Michael & Tendon Research Group Bispebjerg, T. R. G. B., 28 Sep 2017, In: The New England Journal of Medicine. 377, 13, p. 1300-1301 2 p.

    Research output: Contribution to journal › Comment/debate › Research

  36. Published

    Release of tensile strain on engineered human tendon tissue disturbs cell adhesions, changes matrix architecture, and induces an inflammatory phenotype

    Bayer, M. L., Schjerling, Peter, Herchenhan, A., Zeltz, C., Heinemeier, K. M., Christensen, L., Krogsgaard, Michael R., Gullberg, D. & Kjær, Michael, 2014, In: PLOS ONE. 9, 1, p. 1-16 16 p., e86078.

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Published

    Behandling af akutte muskelskader

    Bayer, M. L., Mackey, Abigail, Magnusson, Stig Peter, Krogsgaard, Michael R. & Kjær, Michael, 18 Feb 2019, In: Ugeskrift for Laeger. 181, 8, 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. Published

    Influence of the integrin alpha-1 subunit and its relationship with high-fat diet upon extracellular matrix synthesis in skeletal muscle and tendon

    Bayer, M. L., Svensson, R. B., Schjerling, P., Williams, A. S., Wasserman, D. H. & Kjær, Michael, 2020, In: Cell and Tissue Research. 381, 1, p. 177-187

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. Published

    Role of tissue perfusion, muscle strength recovery, and pain in rehabilitation after acute muscle strain injury: A randomized controlled trial comparing early and delayed rehabilitation

    Bayer, M. L., Høgberget-Kalisz, M., Jensen, M. H., Olesen, J. L., Svensson, R. B., Couppé, C., Boesen, Mikael Ploug, Nybing, J. D., Kurt, E. Y., Magnusson, Stig Peter & Kjær, Michael, 2018, In: Scandinavian Journal of Medicine and Science in Sports. 28, 12, p. 2579-2591 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  40. Published

    Chronic Sequelae After Muscle Strain Injuries: Influence of Heavy Resistance Training on Functional and Structural Characteristics in a Randomized Controlled Trial

    Bayer, M. L., Hoegberget-Kalisz, M., Svensson, R. B., Hjortshoej, M. H., Olesen, J. L., Nybing, J. D., Boesen, Mikael Ploug, Magnusson, Stig Peter & Kjær, Michael, 2021, In: American Journal of Sports Medicine. 49, 10, p. 2783-2794 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. Published

    The influence of direct and indirect fibroblast cell contact on human myogenic cell behaviour and gene expression in vitro

    Bechshøft, C. J. L., Schjerling, Peter, Kjær, Michael & Mackey, Abigail, 2019, In: Journal of Applied Physiology. 127, 2, p. 342-355

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. Published

    Age and prior exercise in vivo determine the subsequent in vitro molecular profile of myoblasts and non-myogenic cells derived from human skeletal muscle

    Bechshøft, C. J. L., Jensen, S. M., Schjerling, P., Andersen, J. L., Svensson, R. B., Eriksen, C. S., Mkumbuzi, N. S., Kjær, Michael & Mackey, Abigail, Jun 2019, In: American Journal of Physiology: Cell Physiology. 316, 6, p. C898-C912

    Research output: Contribution to journal › Journal article › Research › peer-review

  43. Published

    Counteracting age-related loss of skeletal muscle mass: a clinical and ethnological trial on the role of protein supplementation and training load (CALM Intervention Study): study protocol for a randomized controlled trial

    Bechshøft, R., Reitelseder, S., Højfeldt, Grith Stougaard, Castro Mejia, J. L., Khakimov, Bekzod, Bin Ahmad, H. F., Kjær, Michael, Engelsen, Søren Balling, Laugesen, S. M. B., Rasmussen, Morten Arendt, Lassen, Aske Juul, Jensen, T., Beyer, N., Serena, A., Perez-Cueto, Federico J.A., Nielsen, Dennis Sandris, Jespersen, Astrid Pernille & Holm, L., 2016, In: Trials. 17, 17 p., 397.

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Published

    The anabolis potential of dietary protein intake on skeletal muscle is prolonged by prior light-load exercise

    Bechshøft, R., Dideriksen, K. J., Reitelseder, S., Scheike, Thomas, Kjær, Michael & Holm, L., 2013, In: Clinical Nutrition. 32, 2, p. 236-244

    Research output: Contribution to journal › Journal article › Research › peer-review

  45. Published

    Improved skeletal muscle mass and strength after heavy strength training in very old individuals

    Bechshøft, R. L., Malmgaard-Clausen, N. M., Gliese, B., Beyer, N., Mackey, Abigail, Andersen, J. L., Kjær, Michael & Holm, L., 2017, In: Experimental Gerontology. 92, p. 96-105 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  46. Published

    RNF138 joins the HR team

    Bekker-Jensen, Simon Holst & Mailand, Niels, Oct 2015, In: Nature Cell Biology. 17, 11, p. 1375-7 3 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. Published

    Ubiquitin and the DNA damage response: a new handle on histones

    Bekker-Jensen, Simon Holst & Mailand, Niels, 1 Sep 2012, In: Cell Cycle. 11, 17, p. 3153 1 p.

    Research output: Contribution to journal › Comment/debate › Research › peer-review

  48. Published

    ICLs: a chicken without an egg

    Bekker-Jensen, Simon Holst & Mailand, Niels, 2012, In: Nature Reviews. Molecular Cell Biology. 13, 6, p. 342

    Research output: Contribution to journal › Review › Research › peer-review

  49. Published

    The ubiquitin- and SUMO-dependent signaling response to DNA double-strand breaks

    Bekker-Jensen, Simon Holst & Mailand, Niels, 12 Jun 2011, In: FEBS Letters. 585, p. 2914-2919 6 p.

    Research output: Contribution to journal › Review › Research › peer-review

  50. Published

    Dynamics of the DNA repair proteins WRN and BLM in the nucleoplasm and nucleoli

    Bendtsen, K. M., Jensen, M. B., May, A., Rasmussen, Lene Juel, Trusina, Ala, Bohr, Vilhelm & Jensen, Mogens Høgh, 14 Nov 2014, In: European Biophysics Journal. 43, 10-11, p. 509-516

    Research output: Contribution to journal › Journal article › Research › peer-review

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