Damage and Repair

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  1. 2017
  2. Published

    Proteomics Reveals Global Regulation of Protein SUMOylation by ATM and ATR Kinases during Replication Stress

    Munk, S., Sigurðsson, J. O., Xiao, Z., Batth, Tanveer Singh, Franciosa, Giulia, von Stechow, L., Lopez-Contreras, Andres, Vertegaal, A. C. O. & Olsen, Jesper Velgaard, 2017, In: Cell Reports. 21, 2, p. 546-558 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Rev1 contributes to proper mitochondrial function via the PARP-NAD(+)-SIRT1-PGC1 alpha axis

    Fakouri, N. B., Durhuus, J. A., Regnell, C. E., Angleys, M., Desler, Claus, Hasan-Olive, M., Martin-Pardillos, A., Tsaalbi-Shtylik, A., Thomsen, Kirsten Joan, Lauritzen, Martin, Bohr, Vilhelm, de Wind, N., Bergersen, L. H. & Rasmussen, Lene Juel, 2017, In: Scientific Reports. 7, 14 p., 12480.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Simvastatin and atorvastatin reduce the mechanical properties of tendon constructs in vitro and introduce catabolic changes in the gene expression pattern

    Eliasson, P., Svensson, R. B., Giannopoulos, A., Eismark, C., Kjær, Michael, Schjerling, P. & Heinemeier, K. M., 2017, In: PLOS ONE. 12, 3, 16 p., e0172797.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Stalled replication forks generate a distinct mutational signature in yeast

    Larsen, N. B., Liberti, S. E., Vogel, Ivan, Jorgensen, S. W., Hickson, Ian David & Mankouri, H. W., 2017, In: Proceedings of the National Academy of Sciences of the United States of America. 114, 36, p. 9665-9670

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Sub-Clinical Cognitive Decline and Resting Cerebral Blood Flow in Middle Aged Men

    Henriksen, O. M., Hansen, N. L., Osler, Merete, Mortensen, Erik Lykke, Hallam, D. M., Pedersen, E. T., Chappell, M., Lauritzen, Martin & Rostrup, E., 2017, In: PLOS ONE. 12, 1, 15 p., e0169912.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    The "enemies within": regions of the genome that are inherently difficult to replicate

    Bhowmick, Rahul & Hickson, Ian David, 2017, In: F1000Research. 6, 7 p., 666.

    Research output: Contribution to journal › Review › Research › peer-review

  8. Published

    The breaking and making of healthy adult human skeletal muscle in vivo

    Mackey, Abigail & Kjær, Michael, 2017, In: Skeletal Muscle. 7, 18 p., 24.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Tomatidine enhances lifespan and healthspan in C. elegans through mitophagy induction via the SKN-1/Nrf2 pathway

    Fang, E. F., Waltz, T. B., Kassahun, H., Lu, Q., Kerr, J. S., Morevati, M., Fivenson, E. M., Wollman, B. N., Marosi, K., Wilson, M. A., Iser, W. B., Eckley, D. M., Zhang, Y., Lehrmann, E., Goldberg, I. G., Scheibye-Knudsen, Morten, Mattson, M. P., Nilsen, H., Bohr, Vilhelm & Becker, K. G., 2017, In: Scientific Reports. 7, 46208.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Visual steady state in relation to age and cognitive function

    Horwitz, A., Dyhr Thomsen, M., Wiegand, I., Horwitz, H., Klemp, Marc Patrick Brag, Nikolic, M., Rask, L., Lauritzen, Martin & Benedek, Krisztina, 2017, In: PLOS ONE. 12, 2, 23 p., e0171859.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. 2016
  12. Published

    RAD52 Facilitates Mitotic DNA Synthesis Following Replication Stress

    Bhowmick, Rahul, Minocherhomji, S. & Hickson, Ian David, 15 Dec 2016, In: Molecular Cell. 64, 6, p. 1117-1126 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Cognitive Change during the Life Course and Leukocyte Telomere Length in Late Middle-Aged Men

    Rask, L., Bendix, L., Harbo, M., Fagerlund, Birgitte, Mortensen, Erik Lykke, Lauritzen, Martin & Osler, Merete, 9 Dec 2016, In: Frontiers in Aging Neuroscience. 8, 7 p., 300.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Effect of aging and exercise on the tendon

    Svensson, R. B., Heinemeier, K. M., Couppé, Christian, Kjær, Michael & Magnusson, Stig Peter, 1 Dec 2016, In: Journal of Applied Physiology. 121, 6, p. 1237-1246 10 p.

    Research output: Contribution to journal › Review › Research › peer-review

  15. Published

    3-Hydroxybutyrate regulates energy metabolism and induces BDNF expression in cerebral cortical neurons

    Marosi, K., Kim, S. W., Moehl, K., Scheibye-Knudsen, Morten, Cheng, A., Cutler, R., Camandola, S. & Mattson, M. P., Dec 2016, In: Journal of Neurochemistry. 139, 5, p. 769-781 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    A Novel Rrm3 Function in Restricting DNA Replication via an Orc5-Binding Domain Is Genetically Separable from Rrm3 Function as an ATPase/Helicase in Facilitating Fork Progression

    Syed, S., Desler, Claus, Rasmussen, Lene Juel & Schmidt, K. H., Dec 2016, In: P L o S Genetics. 12, 12, 28 p., e1006451.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    A ketogenic diet accelerates neurodegeneration in mice with induced mitochondrial DNA toxicity in the forebrain

    Lauritzen, K. H., Hasan-Olive, M. M., Regnell, C. E., Kleppa, L., Scheibye-Knudsen, Morten, Gjedde, Albert, Klungland, A., Bohr, Vilhelm, Storm-Mathisen, J. & Bergersen, L. H., Dec 2016, In: Neurobiology of Aging. 48, p. 34-47

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Interventions for age-related diseases: Shifting the paradigm

    Figueira, I., Fernandes, A., Mladenovic Djordjevic, A., Lopez-Contreras, Andres, Henriques, C. M., Selman, C., Ferreiro, E., Gonos, E. S., Trejo, J. L., Misra, J., Rasmussen, Lene Juel, Xapelli, S., Ellam, T. & Bellantuono, I., Dec 2016, In: Mechanisms of Ageing and Development. 160, p. 69-92 24 p.

    Research output: Contribution to journal › Review › Research › peer-review

  19. Published

    Isometric abdominal wall muscle strength assessment in individuals with incisional hernia: a prospective reliability study

    Jensen, K. K., Kjær, Michael & Jørgensen, Lars Nannestad, Dec 2016, In: Hernia. 20, 6, p. 831-837

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Physical activity as intervention for age-related loss of muscle mass and function: protocol for a randomised controlled trial (the LISA study)

    Eriksen, C. S., Garde, Ellen, Reislev, N. L., Wimmelmann, Cathrine Lawaetz, Bieler, T., Ziegler, A. K., Gylling, A. T., Dideriksen, K. J., Siebner, Hartwig Roman, Mortensen, Erik Lykke & Kjær, Michael, Dec 2016, In: B M J Open. 6, 12, p. 1-13 13 p., e012951.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    DNA Damage Signaling Instructs Polyploid Macrophage Fate in Granulomas

    Herrtwich, L., Nanda, I., Evangelou, K., Nikolova, T., Horn, V., Sagar, Erny, D., Stefanowski, J., Rogell, L., Klein, C., Gharun, K., Follo, M., Seidl, M., Kremer, B., Muenke, N., Senges, J., Fliegauf, M., Aschman, T., Pfeifer, D., Sarrazin, S. & 18 others, Sieweke, M. H., Wagner, D., Dierks, C., Haaf, T., Ness, T., Zaiss, M. M., Voll, R. E., Deshmukh, S. D., Prinz, M., Goldmann, T., Hoelscher, C., Hauser, A. E., Lopez-Contreras, Andres, Gruen, D., Gorgoulis, V., Diefenbach, A., Henneke, P. & Triantafyllopoulou, A., 17 Nov 2016, In: Cell. 167, 5, p. 1264–1280.e18

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    SCAI promotes DNA double-strand break repair in distinct chromosomal contexts

    Hansen, R. K., Mund, A., Poulsen, S. L., Sandoval, M., Klement, K., Tsouroula, K., Tollenaere, M. A. X., Räschle, M., Soria, R., Offermanns, S., Worzfeld, T., Grosse, R., Brandt, D. T., Rozell, B., Mann, M., Cole, F., Soutoglou, E., Goodarzi, A. A., Daniel, J. A., Mailand, N. & 1 others, Bekker-Jensen, Simon Holst, 7 Nov 2016, In: Nature Cell Biology. 18, 12, p. 1357–1366

    Research output: Contribution to journal › Letter › Research › peer-review

  23. Published

    Cockayne syndrome group A and B proteins converge on transcription-linked resolution of non-B DNA

    Scheibye-Knudsen, M., Tseng, A., Jensen, M. B., Scheibye-Alsing, K., Fang, E. F., Iyama, T., Bharti, S. K., Marosi, K., Froetscher, L., Kassahun, H., Eckley, D. M., Maul, R. W., Bastian, P., De, S., Ghosh, S., Nilsen, H., Goldberg, I. G., Mattson, M. P., Wilson, D. M. . III., Brosh, R. M. . J. & 2 others, Gorospe, M. & Bohr, Vilhelm, 1 Nov 2016, In: National Academy of Sciences. Proceedings. 113, 44, p. 12502-12507

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Activation of the ATR kinase by the RPA-binding protein ETAA1

    Haahr, Peter Thorlund, Hoffmann, Saskia, Tollenaere, M. A. X., Ho, T., Toledo Lazaro, L. I., Mann, Matthias, Bekker-Jensen, Simon Holst, Räschle, M. & Mailand, Niels, Nov 2016, In: Nature Cell Biology. 18, 11, p. 1196–1207

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Neurodegeneration in Accelerated Aging

    Scheibye-Knudsen, Morten, Nov 2016, In: Danish Medical Journal. 63, 11, 21 p., B5308.

    Research output: Contribution to journal › Review › Research › peer-review

  26. Published

    PICH promotes mitotic chromosome segregation: Identification of a novel role in rDNA disjunction

    Nielsen, Christian Friberg & Hickson, Ian David, 17 Oct 2016, In: Cell Cycle. 15, 20, p. 2704-2711 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    NAD(+) Replenishment Improves Lifespan and Healthspan in Ataxia Telangiectasia Models via Mitophagy and DNA Repair

    Fang, E. F., Kassahun, H., Croteau, D. L., Scheibye-Knudsen, M., Marosi, K., Lu, H., Shamanna, R. A., Kalyanasundaram, S., Bollineni, R. C., Wilson, M. A., Iser, W. B., Wollman, B. N., Morevati, M., Li, J., Kerr, J. S., Lu, Q., Waltz, T. B., Tian, J., Sinclair, D. A., Mattson, M. P. & 2 others, Nilsen, H. & Bohr, Vilhelm, 11 Oct 2016, In: Cell Metabolism. 24, 4, p. 566-581 16 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

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