Damage and Repair

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  1. 2022
  2. Published

    Human derived tendon cells contribute to myotube formation in vitro

    Tsuchiya, Y., Bayer, M. L., Schjerling, Peter, Soendenbroe, C. & Kjær, Michael, 2022, In: Experimental Cell Research. 417, 1, 113164.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Lactate receptor HCAR1 regulates neurogenesis and microglia activation after neonatal hypoxia-ischemia

    Kennedy, L., Glesaaen, E. R., Palibrk, V., Pannone, M., Wang, W., Al-Jabri, A., Suganthan, R., Meyer, N., Austbø, M. L., Lin, X., Bergersen, L. H., Bjørås, M. & Rinholm, J. E., 2022, In: eLife. 11, 21 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Meeting Report: Aging Research and Drug Discovery

    Meron, E., Thaysen, M., Angeli, S., Antebi, A., Barzilai, N., Baur, J. A., Bekker-Jensen, S., Birkisdottir, M., Bischof, E., Bruening, J., Brunet, A., Buchwalter, A., Cabreiro, F., Cai, S., Chen, B. H., Ermolaeva, M., Ewald, C. Y., Ferrucci, L., Florian, M. C., Fortney, K. & 58 others, Freund, A., Georgievskaya, A., Gladyshev, V. N., Glass, D., Golato, T., Gorbunova, V., Hoejimakers, J., Houtkooper, R. H., Jager, S., Jaksch, F., Janssens, G., Jensen, M. B., Kaeberlein, M., Karsenty, G., de Keizer, P., Kennedy, B., Kirkland, J. L., Kjær, Michael, Kroemer, G., Lee, K. F., Lemaitre, J. M., Liaskos, D., Longo, V. D., Lu, Y. X., MacArthur, M. R., Maier, A. B., Manakanatas, C., Mitchell, S. J., Moskalev, A., Niedernhofer, L., Ozerov, I., Partridge, L., Passegué, E., Petr, Michael Angelo, Peyer, J., Radenkovic, D., Rando, T. A., Rattan, S., Riedel, C. G., Rudolph, L., Ai, R., Serrano, M., Schumacher, B., Sinclair, D. A., Smith, R., Suh, Y., Taub, P., Trapp, A., Trendelenburg, A. U., Valenzano, D. R., Verburgh, K., Verdin, E., Vijg, J., Westendorp, Rudi GJ, Zonari, A., Bakula, Daniela Janina, Zhavoronkov, A. & Scheibye-Knudsen, Morten, 2022, In: Aging. 14, 2, p. 530-543 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    NIH SenNet Consortium to map senescent cells throughout the human lifespan to understand physiological health

    Lee, P. J., Benz, C. C., Blood, P., Börner, K., Campisi, J., Chen, F., Daldrup-Link, H., De Jager, P., Ding, L., Duncan, F. E., Eickelberg, O., Fan, R., Finkel, T., Furman, D., Garovic, V., Gehlenborg, N., Glass, C., Heckenbach, I., Joseph, Z. B., Katiyar, P. & 48 others, Kim, S. J., Königshoff, M., Kuchel, G. A., Lee, H., Lee, J. H., Ma, J., Ma, Q., Melov, S., Metis, K., Mora, A. L., Musi, N., Neretti, N., Passos, J. F., Rahman, I., Rivera-Mulia, J. C., Robson, P., Rojas, M., Roy, A. L., Scheibye-Knudsen, Morten, Schilling, B., Shi, P., Silverstein, J. C., Suryadevara, V., Xie, J., Wang, J., Wong, A. I., Niedernhofer, L. J., Wang, S., Anvari, H., Balough, J., Stanford TDA, S. T., University of Connecticut TMC, U. O. C. T., University of Michigan TDA, U. O. M. T., University of Minnesota TMC, U. O. M. T., University of Pittsburgh TMC, U. O. P. T., University of Washington TDA, U. O. W. T., Washington University TMC, W. U. T., Yale TMC, Y. T., SenNet Consortium, S. C., Writing Group, W. G., Brown University TDA, B. U. T., Buck Institute for Research on Aging TMC/TDA, B. I. F. R. O. A. T., Consortium Organization and Data Coordinating Center (CODCC), C. O. A. D. C. C. (., Columbia TMC, C. T., Duke University TMC, D. U. T., Massachusetts General Hospital TDA, M. G. H. T., Mayo Clinic TDA, M. C. T. & National Institute of Health (NIH), N. I. O. H. (., 2022, In: Nature Aging. 2, 12, p. 1090-1100 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    New hallmarks of ageing: a 2022 Copenhagen ageing meeting summary

    Schmauck-Medina, T., Molière, A., Lautrup, S., Zhang, J., Chlopicki, S., Madsen, H. B., Cao, S., Soendenbroe, C., Mansell, E., Vestergaard, M. B., Li, Z., Shiloh, Y., Opresko, P. L., Egly, J. M., Kirkwood, T., Verdin, E., Bohr, V. A., Cox, L. S., Stevnsner, T., Rasmussen, L. J. & 1 others, Fang, E. F., 2022, In: Aging. 14, 16, p. 6829-6839 11 p.

    Research output: Contribution to journal › Review › Research › peer-review

  7. Published

    Nuclear morphology is a deep learning biomarker of cellular senescence

    Heckenbach, Indra John, Mkrtchyan, Garik, Ben Ezra, Michael, Bakula, Daniela Janina, Madsen, Jakob Sture, Nielsen, M. H., Oró, D., Osborne, Brenna, Covarrubias, A. J., Idda, M. L., Gorospe, M., Mortensen, Laust Hvas, Verdin, E., Westendorp, Rudi GJ & Scheibye-Knudsen, Morten, 2022, In: Nature Aging. 2, 8, p. 742-755 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    PICH Supports Embryonic Hematopoiesis by Suppressing a cGAS-STING-Mediated Interferon Response

    Geng, X., Zhang, C., Li, M., Wang, J., Ji, F., Feng, H., Xing, M., Li, F., Zhang, L., Li, W., Chen, Z., Hickson, Ian David, Shen, H. & Ying, S., 2022, In: Advanced Science. 9, 7, 2103837.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    PICH acts as a force-dependent nucleosome remodeler

    Spakman, D., Clement, T. V. M., Biebricher, A. S., King, G. A., Singh, Manika Indrajit, Hickson, Ian David, Peterman, E. J. G. & Wuite, G. J. L., 2022, In: Nature Communications. 13, 7277.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Partial inhibition of mitochondrial-linked pyrimidine synthesis increases tumorigenic potential and lysosome accumulation

    Desler, Claus, Durhuus, J. A., Hansen, T. L. L., Anugula, Sharath, Zelander, N. T., Bøggild, S. & Rasmussen, Lene Juel, 2022, In: Mitochondrion. 64, p. 73-81 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Pathological Tendon Histology in Early and Chronic Human Patellar Tendinopathy

    Malmgaard-Clausen, N. M., Kjær, Michael & Dakin, S. G., 2022, In: Translational Sports Medicine. 2022, 2799665.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    Persistent Deficits after an Achilles Tendon Rupture: A Narrative Review

    Høffner, Rikke, Svensson, R. B., Bjerregaard, N., Kjær, Michael & Magnusson, Stig Peter, 2022, In: Translational Sports Medicine. 2022

    Research output: Contribution to journal › Review › Research › peer-review

  13. Published

    Preserved stem cell content and innervation profile of elderly human skeletal muscle with lifelong recreational exercise

    Soendenbroe, C., Dahl, C. L., Meulengracht, C., Tamáš, M., Svensson, R. B., Schjerling, Peter, Kjær, Michael, Andersen, J. L. & Mackey, Abigail, 2022, In: The Journal of Physiology. 600, 8, p. 1969-1989

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Prevention of Cell Death by Activation of Hydroxycarboxylic Acid Receptor 1 (GPR81) in Retinal Explants

    Vohra, Rupali, Sanz-Morello, B., Tams, A. L. M., Mouhammad, Zaynab Ahmad, Freude, Kristine, Hannibal, Jens, Aldana, Blanca, Bergersen, L. H. & Kolko, Miriam, 2022, In: Cells. 11, 13, 2098.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    RAD51 protects human cells from transcription-replication conflicts

    Bhowmick, Rahul, Lerdrup, Mads, Gadi, Sampath Amitash, Rossetti, G. G., Singh, Manika Indrajit, Liu, Ying, Halazonetis, T. D. & Hickson, Ian David, 2022, In: Molecular Cell. 82, 18, p. 3366-3381.e9

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    RANKL regulates testicular cancer growth and Denosumab treatment has suppressive effects on GCNIS and advanced seminoma

    Andreassen, C. H., Lorenzen, M., Nielsen, J. E., Kafai Yahyavi, S., Toft, Birgitte Grønkær, Ingerslev, L. R., Clemmensen, Christoffer, Rasmussen, Lene Juel, Bokemeyer, C., Juul, Anders, Jørgensen, A. & Jensen, M. B., 2022, In: British Journal of Cancer. 127, p. 408-421

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Ribosome impairment regulates intestinal stem cell identity via ZAKɑ activation

    Silva, J., Alkan, F., Ramalho, S., Snieckute, Goda, Prekovic, S., Garcia, A. K., Hernández-Pérez, S., van der Kammen, R., Barnum, D., Hoekman, L., Altelaar, M., Zwart, W., Suijkerbuijk, S. J. E., Bekker-Jensen, Simon Holst & Faller, W. J., 2022, In: Nature Communications. 13, 1, 4492.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Systems modelling predicts chronic inflammation and genomic instability prevent effective mitochondrial regulation during biological ageing

    Guimera, A. M., Clark, P., Wordsworth, J., Anugula, Sharath, Rasmussen, Lene Juel & Shanley, D. P., 2022, In: Experimental Gerontology. 166, 9 p., 111889.

    Research output: Contribution to journal › Review › Research › peer-review

  19. Published

    The hallmarks of aging

    Gilmour, B. C., Bergersen, L. H. & Fang, E. F., 2022, Molecular, Cellular, and Metabolic Fundamentals of Human Aging. Academic Press, p. 1-6 6 p.

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  20. Published

    The proteomic profile of the human myotendinous junction

    Karlsen, Anders, Gonzalez-Franquesa, A., Jakobsen, J. R., Krogsgaard, Michael R., Koch, M., Kjær, Michael, Schiaffino, S., Mackey, Abigail & Deshmukh, Atul Shahaji, 2022, In: iScience. 25, 2, 19 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    The regional turnover of cartilage collagen matrix in late-stage human knee osteoarthritis

    Jørgensen, A. E. M., Agergaard, J., Schjerling, Peter, Heinemeier, K. M., van Hall, Gerrit & Kjær, Michael, 2022, In: Osteoarthritis and Cartilage. 30, 6, p. 886-895

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. 2021
  23. Published

    Variation in the risk of colorectal cancer in families with Lynch syndrome: a retrospective cohort study

    The International Mismatch Repair Consortium, T. I. M. R. C., Jul 2021, In: The Lancet Oncology. 22, 7, p. 1014-1022 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    A cross-sectional study of functional and metabolic changes during aging through the lifespan in male mice

    Petr, Michael Angelo, Alfaras, I., Krawcyzk, M., Bair, W. N., Mitchell, S. J., Morrell, C. H., Studenski, S. A., Price, N. L., Fishbein, K. W., Spencer, R. G., Scheibye-Knudsen, Morten, Lakatta, E. G., Ferrucci, L., Aon, M. A., Bernier, M. & de Cabo, R., 2021, In: eLife. 10, 25 p., e62952.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    ATP induces contraction of cultured brain capillary pericytes, via activation of P2Y type purinergic receptors

    Hørlyck, S., Cai, Changsi, Helms, H. C., Lauritzen, Martin & Larsen, Birger Brodin, 2021, In: American Journal of Physiology: Heart and Circulatory Physiology. 320, p. H699–H712 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    Adipocytes are present at human and murine myotendinous junctions

    Jakobsen, J. R., Jakobsen, N. R., Mackey, Abigail, Knudsen, A. B., Hannibal, Jens, Koch, M., Kjær, Michael & Krogsgaard, Michael R., 2021, In: Translational Sports Medicine. 4, 2, p. 223-230

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    Age-related myofiber atrophy in old mice is reversed by ten weeks voluntary high-resistance wheel running

    Olesen, A. T., Alchow-Moller, L., Bendixen, R. D., Kjær, Michael, Svensson, R. B., Andersen, J. L. & Magnusson, Stig Peter, 2021, In: Experimental Gerontology. 143, 111150.

    Research output: Contribution to journal › Journal article › Research › peer-review

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