Damage and Repair

  1. 2014
  2. Published

    Accuracy of MRI technique in measuring tendon cross-sectional area

    Couppé, Christian, Svensson, R. B., Elbrønd (Bibs), Vibeke Sødring, Hansen, P., Kjær, Michael & Magnusson, Stig Peter, 2014, In: Clinical Physiology and Functional Imaging. 34, 3, p. 237-241 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Basic Components of Connective Tissues and Extracellular Matrix: Elastin, Fibrillin, Fibulins, Fibrinogen, Fibronectin, Laminin, Tenascins and Thrombospondins

    Halper, J. & Kjær, Michael, 2014, Progress in Heritable Soft Connective Tissue Diseases. Vol. 802. p. 31-47 17 p. (Advances in Experimental Medicine and Biology).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  4. Published

    Bengt Saltin (1935-2014)

    Bangsbo, Jens, Kjær, Michael & Hellsten, Ylva, 2014, In: Journal of Physiology. 592, 23, p. 5149-5151 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Effect of growth hormone on aging connective tissue in muscle and tendon - gene expression, morphology and function following immobilization and rehabilitation

    Boesen, A. P., Dideriksen, K. J., Couppé, Christian, Magnusson, Stig Peter, Schjerling, Peter, Boesen, M., Aagaard, P., Kjær, Michael & Langberg, Henning, 2014, In: Journal of Applied Physiology. 116, p. 192-203 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Functional adaptation of tendon and skeletal muscle to resistance training in three patients with genetically verified classic Ehlers Danlos Syndrome

    Møller, M. B., Kjær, Michael, Svensson, R. B., Andersen, J. L., Magnusson, Stig Peter & Nielsen, R. H., 2014, In: M.L.T.J. Muscles, Ligaments and Tendons Journal. 4, 3, p. 315-323 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Influence of Sex and Estrogen on Musculotendinous Protein Turnover at Rest and After Exercise

    Hansen, M. & Kjær, Michael, 2014, In: Exercise and Sport Sciences Reviews. 42, 4, p. 183–192 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Integrated Measurements of Electrical Activity, Oxygen Tension, Blood Flow, and Ca2+ -Signaling in Rodents In Vivo

    Mathiesen, C., Thomsen, K. & Lauritzen, Martin, 2014, Brain Energy Metabolism. Hirrlinger, J. & Waagepetersen, H. S. (eds.). p. 243-264 22 p.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterEducationpeer-review

  9. Published

    Introducing the hypothome: a way to integrate predicted proteins in interactomes

    Desler, Claus, Zambach, S., Suravajhala, P. & Rasmussen, Lene Juel, 2014, In: International Journal of Bioinformatics Research and Applications. 10, 6, p. 647-52 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Lactate transport and receptor actions in cerebral malaria

    Mariga, S. T., Kolko, Miriam, Gjedde, Albert & Bergersen, L. H., 2014, In: Frontiers in Neuroscience. 8, p. 1-6 6 p., 2.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Neurovascular coupling in relation to cortical spreading depression

    Piilgaard, H. & Lauritzen, Martin, 2014, In: Neuromethods. 88, p. 273-286 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Release of tensile strain on engineered human tendon tissue disturbs cell adhesions, changes matrix architecture, and induces an inflammatory phenotype

    Bayer, M. L., Schjerling, Peter, Herchenhan, A., Zeltz, C., Heinemeier, K. M., Christensen, L., Krogsgaard, Michael R., Gullberg, D. & Kjær, Michael, 2014, In: PLOS ONE. 9, 1, p. 1-16 16 p., e86078.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    The Escherichia coli Tus-Ter replication fork barrier causes site-specific DNA replication perturbation in yeast

    Larsen, N. B., Sass, E., Suski, C., Mankouri, H. W. & Hickson, Ian David, 2014, In: Nature Communications. 5, p. 1-10 10 p., 3574.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    UBL5 is essential for pre-mRNA splicing and sister chromatid cohesion in human cells

    Oka, Y., Varmark, H., Vitting-Seerup, K., Beli, P., Waage, J. E., Hakobyan, A., Mistrik, M., Choudhary, Chunaram, Rohde, M., Bekker-Jensen, Simon Holst & Mailand, Niels, 2014, In: E M B O Reports. 15, 9, p. 956-964 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Validation of hippocampal texture for early Alzheimer’s disease detection: generalization to independent cohorts and extrapolation to very early signs of dementia

    Sørensen, L., Igel, Christian, Hansen, N. L., Lauritzen, Martin, Osler, Merete, Rostrup, Egill & Nielsen, Mads, 2014, In: Alzheimer's & Dementia. 10, 4, Supplement, p. P133 1 p.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  16. Published

    White matter lactate: Does it matter?

    Rinholm, J. E. & Bergersen, L. H., 2014, In: Neuroscience. 276, p. 109-116 8 p.

    Research output: Contribution to journalReviewResearchpeer-review

  17. 2013
  18. Published

    Life-long endurance exercise in humans: circulating levels of inflammatory markers and leg muscle size

    Mikkelsen, U. R., Couppé, Christian, Karlsen, Anders, Grosset, J. F., Schjerling, Peter, Mackey, Abigail, Klausen, H. H., Magnusson, Stig Peter & Kjær, Michael, 30 Nov 2013, In: Mechanisms of Ageing and Development. 134, 11-12, p. 531-40 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Relationships between human vitality and mitochondrial respiratory parameters, reactive oxygen species production and dNTP levels in peripheral blood mononuclear cells

    Maynard, S., Keijzers, G., Gram, M., Desler, Claus, Bendix, L., Budtz-Joergensen, Esben, Molbo, Drude, Croteau, D. L., Osler, Merete, Stevnsner, T. V., Rasmussen, Lene Juel, Dela, Flemming, Avlund, K. & Bohr, Vilhelm, 30 Nov 2013, In: Aging. p. 850-864 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    FBH1 helicase disrupts RAD51 filaments in vitro and modulates homologous recombination in mammalian cells

    Simandlova, J., Zagelbaum, J., Payne, M. J., Chu, W. K., Shevelev, I., Hanada, K., Chatterjee, S., Reid, D. A., Liu, Ying, Janscak, P., Rothenberg, E. & Hickson, Ian David, 22 Nov 2013, In: The Journal of Biological Chemistry. 288, 47, p. 34168-80 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    ATR Prohibits Replication Catastrophe by Preventing Global Exhaustion of RPA

    Toledo Lazaro, L. I., Altmeyer, M., Rask, M., Lukas, Claudia, Larsen, D. H., Povlsen, L. K., Bekker-Jensen, Simon Holst, Mailand, Niels, Bartek, J. & Lukas, Jiri, 21 Nov 2013, In: Cell. 155, 5, p. 1088-1103 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Monocarboxylate transporters in temporal lobe epilepsy: roles of lactate and ketogenic diet

    Lauritzen, F., Eid, T. & Bergersen, L. H., 19 Nov 2013, In: Brain Structure and Function (Print Edition).

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    A Role for BLM in Double-Strand Break Repair Pathway Choice: Prevention of CtIP/Mre11-Mediated Alternative Nonhomologous End-Joining.

    Grabarz, A., Guirouilh-Barbat, J., Barascu, A., Pennarun, G., Genet, D., Rass, E., Germann, S. M., Bertrand, P., Hickson, Ian David & Lopez, B. S., 17 Oct 2013, In: Cell Reports. 5, 1, p. 21-28 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    How unfinished business from S-phase affects mitosis and beyond

    Mankouri, H. W., Huttner, D. & Hickson, Ian David, 16 Oct 2013, In: EMBO Journal. 32, 20, p. 2661-71 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Synthesis and SAR studies of 5-(pyridin-4-yl)-1,3,4-thiadiazol-2-amine derivatives as potent inhibitors of Bloom helicase

    Rosenthal, A. S., Dexheimer, T. S., Gileadi, O., Nguyen, G. H., Chu, W. K., Hickson, Ian David, Jadhav, A., Simeonov, A. & Maloney, D. J., 15 Oct 2013, In: Bioorganic & Medicinal Chemistry Letters. 23, 20, p. 5660-6 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    A new cellular stress response that triggers centriolar satellite reorganization and ciliogenesis

    Villumsen, B. H., Danielsen, J. R., Povlsen, L., Sylvestersen, K. B., Merdes, A., Beli, P., Yang, Y., Choudhary, Chunaram, Nielsen, Michael Lund, Mailand, Niels & Bekker-Jensen, Simon Holst, 11 Oct 2013, In: E M B O Journal. 32, 23, p. 3029-3040

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    DNA damage response, bioenergetics, and neurological disease: the challenge of maintaining brain health in an aging human population

    Rasmussen, Lene Juel, Shiloh, Y., Bergersen, L. H., Sander, M., Bohr, Vilhelm & Tønjum, T., Oct 2013, In: Mechanisms of Ageing and Development. 134, 10, p. 427-33 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Tendon and skeletal muscle matrix gene expression and functional responses to immobilisation and rehabilitation in young males: Effect of growth hormone administration

    Boesen, A. P., Dideriksen, K., Couppé, Christian, Magnusson, P., Schjerling, Peter, Boesen, M., Kjær, Michael & Langberg, Henning, 30 Sep 2013, In: Journal of Physiology. p. 6039-6052

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    PICH: A DNA Translocase Specially Adapted for Processing Anaphase Bridge DNA

    Biebricher, A., Hirano, S., Enzlin, J., Wiechens, N., Streicher, W., Huttner, D., Wang, L., Nigg, E., Owen-Hughes, T., Liu, Ying, Peterman, E., Wuite, G. & Hickson, Ian David, 12 Sep 2013, In: Molecular Cell. 51, 5, p. 691-701 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    The changing brain--insights into the mechanisms of neural and behavioral adaptation to the environment

    Bergersen, L. H., Bramham, C. R., Hugdahl, K., Sander, M. & Storm-Mathisen, J., 5 Sep 2013, In: Neuroscience. 247, p. 412-22 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    MUS81 promotes common fragile site expression

    Ying, S., Minocherhomji, S., Chan, K. L., Palmai-Pallag, T., Chu, W. K., Wass, T. A., Mankouri, H. W., Liu, Ying & Hickson, Ian David, Aug 2013, In: Nature Cell Biology. 15, 8, p. 1001-1007 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    Low dopamine D5 receptor density in hippocampus in an animal model of attention-deficit/hyperactivity disorder (ADHD)

    Medin, T., Rinholm, J. E., Owe, S. G., Sagvolden, T., Gjedde, Albert, Storm-Mathisen, J. & Bergersen, L. H., 9 Jul 2013, In: Neuroscience. 242, p. 11-20 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    Disease-causing mutations in the XIAP BIR2 domain impair NOD2-dependent immune signalling

    Damgaard, R. B., Fiil, Berthe Katrine, Speckmann, C., Yabal, M., Stadt, U. Z., Bekker-Jensen, Simon Holst, Jost, P. J., Ehl, S., Mailand, Niels & Gyrd-Hansen, Mads, 1 Jul 2013, In: E M B O Journal. 5, p. 1278-1295 18 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    OTULIN Restricts Met1-Linked Ubiquitination to Control Innate Immune Signaling

    Fiil, Berthe Katrine, Damgaard, R. B., Wagner, S. A., Keusekotten, K., Fritsch, M., Bekker-Jensen, Simon Holst, Mailand, Niels, Choudhary, Chunaram, Komander, D. & Gyrd-Hansen, Mads, 27 Jun 2013, In: Molecular Cell. 50, 6, p. 818-30 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    RNF111/Arkadia is a SUMO-targeted ubiquitin ligase that facilitates the DNA damage response

    Poulsen, S. L., Hansen, R. K., Wagner, S. A., van Cuijk, L., van Belle, G. J., Streicher, W., Wikström, M., Choudhary, Chunaram, Houtsmuller, A. B., Marteijn, J. A., Bekker-Jensen, Simon Holst & Mailand, Niels, 10 Jun 2013, In: Journal of Cell Biology. 201, 6, p. 797-807 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    Genetic screens to identify pathogenic gene variants in the common cancer predisposition Lynch syndrome

    Drost, M., Lützen, A., van Hees, S., Ferreira, D., Calléja, F., Zonneveld, J. B. M., Nielsen, Finn Cilius, Rasmussen, Lene Juel & de Wind, N., 4 Jun 2013, In: Proceedings of the National Academy of Science of the United States of America. 110, 23, p. 9403-8 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    Response to: Design of a core classification process for DNA mismatch repair variations of a priori unknown functional significance

    Rasmussen, Lene Juel, Heinen, C. D., Royer-Pokora, B., Drost, M., Tavtigian, S., Hofstra, R. M. W. & de Wind, N., Jun 2013, In: Human Mutation. 34, 6, p. 923-4 2 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    Lactate Receptor Sites Link Neurotransmission, Neurovascular Coupling, and Brain Energy Metabolism

    Lauritzen, K. H., Morland, C., Puchades, M., Holm-Hansen, S., Hagelin, E. M., Lauritzen, F., Attramadal, H., Storm-Mathisen, J., Gjedde, Albert & Bergersen, L. H., 21 May 2013, In: Cerebral cortex (New York, N.Y. : 1991). p. 1-12 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Regulation of PCNA-protein interactions for genome stability

    Mailand, Niels, Gibbs-Seymour, I. & Bekker-Jensen, Simon Holst, May 2013, In: Nature Reviews. Molecular Cell Biology. 14, 5, p. 269-82 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    The deubiquitylating enzyme USP44 counteracts the DNA double-strand break response mediated by the RNF8 and RNF168 ubiquitin ligases

    Mosbech, A., Lukas, Claudia, Bekker-Jensen, Simon Holst & Mailand, Niels, 24 Apr 2013, In: Journal of Biological Chemistry. 288, p. 16579-16587 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    Myogenic, matrix and growth factor mRNA expression in human skeletal muscle: effect of contraction intensity and feeding

    Agergaard, J., Reitelseder, S., Pedersen, T. G., Doessing, S., Schjerling, P., Langberg, Henning, Miller, B. F., Aagaard, P., Kjær, Michael & Holm, L., 20 Mar 2013, In: Muscle & Nerve. 47, 5, p. 748-759 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    Multiscale Vision Model Highlights Spontaneous Glial Calcium Waves Recorded by 2-Photon Imaging in Brain Tissue: Detection Calcium Waves using Multiscale Vision Model

    Brazhe, A., Mathiesen, C. & Lauritzen, Martin, Mar 2013, In: NeuroImage. 68, p. 192-202 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    Morphological adaptation of muscle collagen and receptor of advanced glycation end product (RAGE) in osteoarthritis patients with 12 weeks of resistance training: influence of anti-inflammatory or glucosamine treatment

    Mattiello-Sverzut, A. C., Petersen, S. G., Kjær, Michael & Mackey, Abigail, 27 Feb 2013, In: Rheumatology International.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    Impact of oral contraceptive use and menstrual phases on patellar tendon morphology, biochemical composition and biomechanical properties in female athletes

    Hansen, M. D., Couppé, Christian, Hansen, C., Skovgaard, D., Kovanen, V., Larsen, J. O., Aagaard, P., Magnusson, Stig Peter & Kjær, Michael, 21 Feb 2013, In: Journal of Applied Physiology. 114, p. 998-1008 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    Differentially activated macrophages orchestrate myogenic precursor cell fate during human skeletal muscle regeneration

    Saclier, M., Yacoub-Youssef, H., Mackey, Abigail, Arnold, L., Ardjoune, H., Magnan, M., Sailhan, F., Chelly, J., Pavlath, G. K., Mounier, R., Kjær, Michael & Chazaud, B., Feb 2013, In: Stem Cells. 31, 2, p. 384-96 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    Increased 20-HETE synthesis explains reduced cerebral blood flow but not impaired neurovascular coupling after cortical spreading depression in rat cerebral cortex: 20-HETE synthesis explains reduced CBF after CSD

    Fordsmann, J. C., ko, R., Choi, H. B., Thomsen, Kirsten Joan, Witgen, B. M., Mathiesen, C., Lønstrup, M., Hansen, H. P., MacVicar, B. A. & Lauritzen, Martin, Feb 2013, In: Journal of Neuroscience. p. 2562-2570 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    A Small Molecule Inhibitor of the BLM Helicase Modulates Chromosome Stability in Human Cells

    Nguyen, G. H., Dexheimer, T. S., Rosenthal, A. S., Chu, W. K., Singh, D. K., Mosedale, G., Bachrati, C. Z., Schultz, L., Sakurai, M., Savitsky, P., Abu, M., McHugh, P. J., Bohr, Vilhelm, Harris, C. C., Jadhav, A., Gileadi, O., Maloney, D. J., Simeonov, A. & Hickson, Ian David, 24 Jan 2013, In: Chemistry & Biology. 20, 1, p. 55-62 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    Unaltered lactate and glucose transporter levels in the MPTP mouse model of Parkinson's disease

    Puchades, M., Sogn, C. J., Maehlen, J., Bergersen, L. H. & Gundersen, V., 1 Jan 2013, In: Journal of Parkinson's Disease. 3, 3, p. 371-85 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    Helicobacter pylori infection affects mitochondrial function and DNA repair, thus, mediating genetic instability in gastric cells

    Machado, A. M. D., Desler, C., Boggild, S., Strickertsson, J. A. B., Friis-Hansen, Lennart Jan, Figueiredo, C., Seruca, R. & Rasmussen, Lene Juel, 2013, In: Mechanisms of Ageing and Development. 134, 10, p. 460-466 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    Enterococcus faecalis infection causes inflammation, intracellular oxphos-independent ROS production, and DNA damage in human gastric cancer cells

    Strickertsson, J. A. B., Desler, Claus, Martin-Bertelsen, T., Machado, A. M. D., Wadstrøm, T., Winther, Ole, Rasmussen, Lene Juel & Friis-Hansen, Lennart Jan, 2013, In: PLOS ONE. 8, 4, p. 1-13 13 p., e63147.

    Research output: Contribution to journalJournal articleResearchpeer-review

  51. Published

    Extensive monitoring through multiple blood samples in professional soccer players

    Heisterberg, M. F., Fahrenkrug, J., Krustrup, P., Storskov, A., Kjær, Michael & Andersen, J. L., 2013, In: Journal of Strength and Conditioning Research. 27, 5, p. 1260-1271 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  52. Published

    FBH1 co-operates with MUS81 in inducing DNA double-strand breaks and cell death following replication stress

    Fugger, K., Chu, W. K., Haahr, P., Kousholt, A. N., Beck, H., Payne, M. J., Hanada, K., Hickson, Ian David & Sørensen, Claus Storgaard, 2013, In: Nature Communications. 4, p. 1423

    Research output: Contribution to journalJournal articleResearchpeer-review

  53. Published

    Functional examination of MLH1, MSH2, and MSH6 intronic mutations identified in Danish colorectal cancer patients

    Petersen, S. M., Dandanell, M., Rasmussen, Lene Juel, Gerdes, Anne-Marie Axø, Krogh, L. N., Bernstein, I., Okkels, H., Wikman, F., Nielsen, Finn Cilius & Hansen, Thomas van Overeem, 2013, In: BMC Medical Genetics. 14, p. 103

    Research output: Contribution to journalJournal articleResearchpeer-review

  54. Published

    Genetic screens to identify pathogenic gene variants in the common cancer predisposition Lynch syndrome

    Drost, M., Lützen, A., van Hees, S., Ferreira, D., Calléja, F., Zonneveld, J. B. M., Nielsen, Finn Cilius, Rasmussen, Lene Juel & de Wind, N., 2013, In: Proceedings of the National Academy of Sciences of the United States of America. 110, 23, p. 9403-9408 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  55. Published

    In vitro tendon tissue development from human fibroblasts demonstrates collagen fibril diameter growth associated with a rise in mechanical strength

    Herchenhan, A., Bayer, M. L., Svensson, R. B., Magnusson, Stig Peter & Kjær, Michael, 2013, In: Developmental Dynamics. 242, 1, p. 2-8 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  56. Published

    Lack of tissue renewal in human adult Achilles tendon is revealed by nuclear bomb (14)C

    Heinemeier, K. M., Schjerling, Peter, Heinemeier, J., Magnusson, Stig Peter & Kjær, Michael, 2013, In: F A S E B Journal. 27, 5, p. 2074-2079 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  57. Published

    Natural selection of mitochondria during somatic lifetime promotes healthy aging

    Rodell, A., Rasmussen, Lene Juel, Bergersen, L. H., Singh, K. K. & Gjedde, Albert, 2013, In: Frontiers in Neuroenergetics. 5, p. 1-6 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  58. Published

    No inflammatory gene-expression response to acute exercise in human Achilles tendinopathy

    Pingel, Jessica, Fredberg, U., Mikkelsen, L. R., Schjerling, Peter, Heinemeier, K. M., Kjær, Michael, Harrison, Adrian Paul & Langberg, Henning, 2013, In: European Journal of Applied Physiology. 113, 8, p. 2101-2109 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  59. Published

    Prognostic value of periodic electroencephalographic discharges for neurological patients with profound disturbances of consciousness

    Pedersen, G. L., Rasmussen, S., Gyllenborg, J., Benedek, Krisztina & Lauritzen, Martin, 2013, In: Clinical Neurophysiology. 124, 1, p. 44-51 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  60. Published

    Rapid stimulus-evoked astrocyte Ca2+ elevations and hemodynamic responses in mouse somatosensory cortex in vivo

    Lind, Barbara Lykke, Brazhe, A., Jessen, S. B., Tan, F. C. C. & Lauritzen, Martin, 2013, In: Proceedings of the National Academy of Sciences of the United States of America. 110, 48, p. E4678–E4687 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  61. Published

    RecQ Helicases: Conserved Guardians of Genomic Integrity

    Larsen, N. B. & Hickson, Ian David, 2013, In: Advances in Experimental Medicine and Biology. 767, p. 161-84 24 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  62. Published

    Spontaneous calcium waves in Bergman glia increase with age and hypoxia and may reduce tissue oxygen

    Mathiesen, C., Brazhe, A., Thomsen, Kirsten Joan & Lauritzen, Martin, 2013, In: Journal of Cerebral Blood Flow and Metabolism. 33, p. 161-9 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  63. Published

    The anabolis potential of dietary protein intake on skeletal muscle is prolonged by prior light-load exercise

    Bechshøft, R., Dideriksen, K. J., Reitelseder, S., Scheike, Thomas, Kjær, Michael & Holm, L., 2013, In: Clinical Nutrition. 32, 2, p. 236-244

    Research output: Contribution to journalJournal articleResearchpeer-review

  64. Published

    The effect of acute exercise on collagen turnover in human tendons: influence of prior immobilization period

    Mørch, L. S., Pingel, Jessica, Boesen, M., Kjær, Michael & Langberg, Henning, 2013, In: European Journal of Applied Physiology. 113, 2, p. 449-455 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  65. Published

    The heat shock protein response following eccentric exercise in human skeletal muscle is unaffected by local NSAID infusion

    Mikkelsen, U. R., Paulsen, G., Schjerling, Peter, Helmark, I. C., Langberg, Henning, Kjær, Michael & Heinemeier, K. M., 2013, In: European Journal of Applied Physiology. 113, 7, p. 1883-1893 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  66. Published

    Type VI collagen turnover-related peptides—novel serological biomarkers of muscle mass and anabolic response to loading in young men

    Nedergaard, A., Sun, S., Karsdal, M. A., Henriksen, K. S., Kjær, Michael, Lou, Y., He, Y., Zheng, Q. & Suetta, Charlotte, 2013, In: Journal of Cachexia, Sarcopenia and Muscle. 4, 4, p. 267-275 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  67. Published

    What is the impact of inflammation on the critical interplay between mechanical signaling and biochemical changes in tendon matrix?

    Kjær, Michael, Bayer, M. L., Eliasson, P. & Heinemeier, K. M., 2013, In: Journal of Applied Physiology. 115, 6, p. 879-883 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  68. 2012
  69. Published

    Bone blood flow and metabolism in humans: Effect of muscular exercise and other physiological perturbations

    Heinonen, I., Kemppainen, J., Kaskinoro, K., Langberg, Henning, Knuuti, J., Boushel, R., Kjær, Michael & Kalliokoski, K. K., 21 Dec 2012, In: Journal of Bone and Mineral Research. 28, 5, p. 1068–1074

    Research output: Contribution to journalJournal articleResearchpeer-review

  70. Published

    Functional characterization of MLH1 missense variants identified in Lynch Syndrome patients

    Andersen, S. D., Liberti, S. E., Lützen, A., Drost, M., Bernstein, I., Nilbert, Mef Christina, Dominguez, M., Nyström, M., Hansen, Thomas van Overeem, Christoffersen, J. W., Jäger, A. C., de Wind, N., Nielsen, Finn Cilius, Tørring, P. M. & Rasmussen, Lene Juel, Dec 2012, In: Human Mutation. 33, 12, p. 1647-1655 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  71. Published

    Pathological assessment of mismatch repair gene variants in Lynch syndrome: Past, present, and future

    Rasmussen, Lene Juel, Heinen, C. D., Royer-Pokora, B., Drost, M., Tavtigian, S., Hofstra, R. M. W. & de Wind, N., Dec 2012, In: Human Mutation. 33, 12, p. 1617-25 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  72. Published

    Local administration of growth hormone stimulates tendon collagen synthesis in elderly men

    Vestergaard, P. E., Jørgensen, J. O. L., Olesen, J., Bosnjak, E., Holm, L., Frystyk, J., Langberg, Henning, Kjær, Michael & Hansen, M. D., Nov 2012, In: Journal of Applied Physiology. 113, 9, p. 1432-8 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  73. Published

    Oxidative damage to DNA by diesel exhaust particle exposure in co-cultures of human lung epithelial cells and macrophages

    Jantzen, K., Roursgaard, Martin, Desler, Claus, Loft, Steffen, Rasmussen, Lene Juel & Møller, Peter, Nov 2012, In: Mutagenesis. 27, 6, p. 693-701 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  74. Published

    The helicase and ATPase activities of RECQL4 are compromised by mutations reported in three human patients

    Jensen, M. B., Dunn, C. A., Keijzers, G., Kulikowicz, T., Rasmussen, Lene Juel, Croteau, D. L. & Bohr, Vilhelm, Nov 2012, In: Aging. 4, 11, p. 790-802 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  75. Published

    Histone displacement during nucleotide excision repair

    Dinant, C., Bartek, J. & Bekker-Jensen, Simon Holst, 17 Oct 2012, In: International Journal of Molecular Sciences (Online). 13, 10, p. 13322-13337 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  76. Published

    Oxygen consumption and blood flow coupling in human motor cortex during intense finger tapping: implication for a role of lactate

    Seyedi Vafaee, M., Vang, K., Bergersen, L. H. & Gjedde, Albert, Oct 2012, In: Journal of Cerebral Blood Flow and Metabolism. 32, 10, p. 1859-68 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  77. Published

    Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass

    Povlsen, L. K., Beli, P., Wagner, S. A., Poulsen, S. L., Sylvestersen, K. B., Poulsen, J. W., Nielsen, Michael Lund, Bekker-Jensen, Simon Holst, Mailand, Niels & Choudhary, Chunaram, Oct 2012, In: Nature Cell Biology. 14, 10, p. 1089-98 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  78. Published

    Ubiquitin and the DNA damage response: a new handle on histones

    Bekker-Jensen, Simon Holst & Mailand, Niels, 1 Sep 2012, In: Cell Cycle. 11, 17, p. 3153 1 p.

    Research output: Contribution to journalComment/debateResearchpeer-review

  79. Published

    TRIP12 and UBR5 Suppress Spreading of Chromatin Ubiquitylation at Damaged Chromosomes

    Gudjónsson, Thorkell, Altmeyer, M. F., Savic, V., Toledo Lazaro, L. I., Dinant, C., Grøfte, M., Bartkova, J., Poulsen, M., Oka, Y., Bekker-Jensen, Simon Holst, Mailand, Niels, Neumann, B., Heriche, J., Shearer, R., Saunders, D., Bartek, J., Lukas, Jiri & Lukas, Claudia, 17 Aug 2012, In: Cell. 150, 4, p. 697-709 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  80. Published

    Neuronal inhibition and excitation, and the dichotomic control of brain hemodynamic and oxygen responses

    Lauritzen, Martin, Mathiesen, C., Schaefer, K. & Thomsen, Kirsten Joan, 15 Aug 2012, In: NeuroImage. 62, 2, p. 1040-50 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  81. Published

    GH/IGF-I axis and matrix adaptation of the musculotendinous tissue to exercise in humans

    Heinemeier, K. M., Mackey, Abigail, Doessing, S., Hansen, M., Bayer, M. L., Nielsen, R. H., Herchenhan, A., Malmgaard-Clausen, N. M. & Kjær, Michael, Aug 2012, In: Scandinavian Journal of Medicine & Science in Sports. 22, 4, p. e1-7

    Research output: Contribution to journalJournal articleResearchpeer-review

  82. Published

    Rehabilitation of muscle after injury - the role of anti-inflammatory drugs

    Mackey, Abigail, Mikkelsen, U. R., Magnusson, Stig Peter & Kjær, Michael, Aug 2012, In: Scandinavian Journal of Medicine & Science in Sports. 22, 4, p. e8-14

    Research output: Contribution to journalJournal articleResearchpeer-review

  83. Published

    BLM and RMI1 Alleviate RPA Inhibition of TopoIIIa Decatenase Activity

    Yang, J., Bachrati, C. Z., Hickson, Ian David & Brown, G. W., Jul 2012, In: P L o S One. 7, 7, p. e41208

    Research output: Contribution to journalJournal articleResearchpeer-review

  84. Published

    Celebrating the 30th anniversary of our journal

    Lauritzen, Martin & Dirnagl, U., Jul 2012, In: Journal of Cerebral Blood Flow and Metabolism. 32, 7, p. 1097 1 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  85. Published

    Determining the functional significance of mismatch repair gene missense variants using biochemical and cellular assays

    Heinen, C. D. & Rasmussen, Lene Juel, Jul 2012, In: Hereditary Cancer in Clinical Practice. 10, 1, p. 9

    Research output: Contribution to journalJournal articleResearchpeer-review

  86. Published

    Mitochondria in biology and medicine

    Desler, Claus & Rasmussen, Lene Juel, Jul 2012, In: Mitochondrion. 12, 4, p. 472-6 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  87. Published

    Redistribution of monocarboxylate transporter 2 on the surface of astrocytes in the human epileptogenic hippocampus

    Lauritzen, F., Heuser, K., de Lanerolle, N. C., Lee, T. W., Spencer, D. D., Kim, J. H., Gjedde, Albert, Eid, T. & Bergersen, L. H., Jul 2012, In: Glia. 60, 7, p. 1172-81 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  88. Published

    Is lactate a volume transmitter of metabolic states of the brain?

    Bergersen, L. H. & Gjedde, Albert, 19 Jun 2012, In: Frontiers in Neuroenergetics. 4, Article 5, p. 1-6 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  89. Published

    Alterations of monocarboxylate transporter densities during hypoxia in brain and breast tumour cells

    Cheng, C., Edin, N. F. J., Lauritzen, K. H., Aspmodal, I., Christoffersen, S., Jian, L., Rasmussen, Lene Juel, Pettersen, E. O., Xiaoqun, G. & Bergersen, L. H., Jun 2012, In: Cellular oncology (Dordrecht). 35, 3, p. 217-27 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  90. Published

    Structural And Physiological Changes In Chronically overused Achilles tendons

    Langberg, Henning, Pingel, Jessica, Fredberg, U., Qvortrup, Klaus, Overgaard, J. & Kjær, Michael, May 2012, In: Medicine and Science in Sports and Exercise. 44, p. 116 1 p.

    Research output: Contribution to journalConference articleResearchpeer-review

  91. Published

    Moderate loading of the human osteoarthritic knee joint leads to lowering of intraarticular cartilage oligomeric matrix protein

    Helmark, I. C., Petersen, M. C. H., Christensen, H. E., Kjær, Michael & Langberg, Henning, Apr 2012, In: Rheumatology International. 32, 4, p. 1009-14 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  92. Published

    Effects of 2 weeks lower limb immobilization and two separate rehabilitation regimens on gastrocnemius muscle protein turnover signaling and normalization genes

    Nedergaard, A., Jespersen, J. G., Pingel, Jessica, Christensen, B., Sroczynski, N., Langberg, Henning, Kjær, Michael & Schjerling, Peter, 28 Mar 2012, In: BMC Research Notes. 5, 1, p. 166 1 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  93. Published

    14-3-3 checkpoint regulatory proteins interact specifically with DNA repair protein human exonuclease 1 (hEXO1) via a semi-conserved motif

    Andersen, S. D., Keijzers, G., Rampakakis, E., Engels, K., Luhn, P., El-Shemerly, M., Nielsen, Finn Cilius, Du, Y., May, A., Bohr, Vilhelm, Ferrari, S., Zannis-Hadjopoulos, M., Fu, H. & Rasmussen, Lene Juel, Mar 2012, In: D N A Repair. 11, 3, p. 267-77 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  94. Published

    A novel antirecombinase gains PARIty

    Mankouri, H. W., Chu, W. K. & Hickson, Ian David, Jan 2012, In: Molecular Cell. 45, 1, p. 6-7 2 p.

    Research output: Contribution to journalReviewResearchpeer-review

  95. Published

    A new non-catalytic role for ubiquitin ligase RNF8 in unfolding higher-order chromatin structure

    Luijsterburg, M. S., Acs, K., Ackermann, L., Wiegant, W. W., Bekker-Jensen, Simon Holst, Larsen, D. H., Khanna, K. K., van Attikum, H., Mailand, Niels & Dantuma, N. P., 2012, In: E M B O Journal. 31, 11, p. 2511-27 17 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  96. Published

    A rapid and cell-free assay to test the activity of lynch syndrome-associated MSH2 and MSH6 missense variants

    Drost, M., Zonneveld, J. B. M., van Hees, S., Rasmussen, Lene Juel, Hofstra, R. M. W. & de Wind, N., 2012, In: Human Mutation. 33, 3, p. 488-94 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  97. Published

    DNA damage-inducible SUMOylation of HERC2 promotes RNF8 binding via a novel SUMO-binding Zinc finger

    Danielsen, J. M. R., Povlsen, L. K., Villumsen, B. H., Streicher, W., Nilsson, Jakob, Wikström, M., Bekker-Jensen, Simon Holst & Mailand, Niels, 2012, In: Journal of Cell Biology. 197, 2, p. 179-87 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  98. Published

    DVC1 (C1orf124) is a DNA damage-targeting p97 adaptor that promotes ubiquitin-dependent responses to replication blocks

    Mosbech, A., Gibbs-Seymour, I., Kagias, K., Thorslund, T., Beli, P., Povlsen, L., Nielsen, S. V., Smedegaard, S., Sedgwick, G., Lukas, Claudia, Hartmann-Petersen, Rasmus, Lukas, Jiri, Choudhary, Chunaram, Pocock, R. D. J., Bekker-Jensen, Simon Holst & Mailand, Niels, 2012, In: Nature Structural and Molecular Biology. 19, 11, p. 1084-92 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  99. Published

    Effects of transdermal estrogen on collagen turnover at rest and in response to exercise in postmenopausal women

    Pingel, Jessica, Langberg, Henning, Skovgaard, D. C., Koskinen, S., Flyvbjerg, A., Frystyk, J., Kjær, Michael & Hansen, M., 2012, In: Journal of Applied Physiology. 113, 7, p. 1040-7 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  100. Published

    Genome-wide screens for expressed hypothetical proteins

    Desler, Claus, Durhuus, J. A. & Rasmussen, Lene Juel, 2012, In: Methods in molecular biology (Clifton, N.J.). 815, p. 25-38 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  101. Published

    Human RNF169 is a negative regulator of the ubiquitin-dependent response to DNA double-strand breaks

    Poulsen, M., Lukas, C., Lukas, J., Bekker-Jensen, Simon Holst & Mailand, Niels, 2012, In: Journal of Cell Biology. 197, 2, p. 189-99 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  102. Published

    ICLs: a chicken without an egg

    Bekker-Jensen, Simon Holst & Mailand, Niels, 2012, In: Nature Reviews. Molecular Cell Biology. 13, 6, p. 342

    Research output: Contribution to journalReviewResearchpeer-review

  103. Published

    Is There a Link between Mitochondrial Reserve Respiratory Capacity and Aging?

    Hansen, T. L., Rasmussen, Lene Juel, Desler, Claus, Frederiksen, J. B., Espersen, M. L. M. & Singh, K. K., 2012, In: Journal of Aging Research. 2012, p. 192503 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review