Damage and Repair

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  1. 2017
  2. Published

    Passive Double-Sensory Evoked Coherence Correlates with Long-Term Memory Capacity

    Horwitz, A., Mortensen, Erik Lykke, Osler, Merete, Fagerlund, Birgitte, Lauritzen, Martin & Benedek, K., 14 Dec 2017, In: Frontiers in Human Neuroscience. 11, 21 p., 598.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Handgrip strength shows no improvements in geriatric patients with persistent inflammation during hospitalization

    Norheim, K. L., Bautmans, I. & Kjær, Michael, 1 Dec 2017, In: Experimental Gerontology. 99, p. 115-119 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Bacterial infection increases risk of carcinogenesis by targeting mitochondria

    Strickertsson, J. A. B., Desler, Claus & Rasmussen, Lene Juel, Dec 2017, In: Seminars in Cancer Biology. 47, p. 95-100 6 p.

    Research output: Contribution to journal › Review › Research › peer-review

  5. Published

    Composition and adaptation of human myotendinous junction and neighboring muscle fibers to heavy resistance training

    Jakobsen, J. R., Mackey, Abigail, Knudsen, A. B., Kjær, Michael & Krogsgaard, Michael R., Dec 2017, In: Scandinavian Journal of Medicine & Science in Sports. 27, 12, p. 1547–1559

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Effects of anti-inflammatory (NSAID) treatment on human tendinopathic tissue

    Heinemeier, K. M., Øhlenschlæger, Tommy Frisgaard, Mikkelsen, U. R., Sønder, F., Schjerling, Peter, Svensson, R. B. & Kjær, Michael, Nov 2017, In: Journal of Applied Physiology. 123, 5, p. 1397-1405 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Monogenic diseases of DNA repair

    Keijzers, G., Bakula, Daniela Janina & Scheibye-Knudsen, Morten, Nov 2017, In: New England Journal of Medicine. 377, 19, p. 1868-1876 9 p.

    Research output: Contribution to journal › Review › Research › peer-review

  8. Published

    Early versus Delayed Rehabilitation after Acute Muscle Injury

    Bayer, M. L., Magnusson, Stig Peter, Kjær, Michael & Tendon Research Group Bispebjerg, T. R. G. B., 28 Sep 2017, In: The New England Journal of Medicine. 377, 13, p. 1300-1301 2 p.

    Research output: Contribution to journal › Comment/debate › Research

  9. Published

    Human DNA polymerase delta double-mutant D316A;E318A interferes with DNA mismatch repair in vitro

    Liu, D., Frederiksen, J. H., Liberti, S. E., Lützen, Anne Hoff Kjeldsen, Keijzers, G., Pena-Diaz, J. & Rasmussen, Lene Juel, 19 Sep 2017, In: Nucleic Acids Research. 45, 16, p. 9427-9440 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    In hip osteoarthritis, Nordic Walking is superior to strength training and home based exercise for improving function

    Bieler, T., Siersma, Volkert Dirk, Magnusson, Stig Peter, Kjær, Michael, Christensen, H. E. & Beyer, N., Aug 2017, In: Scandinavian Journal of Medicine & Science in Sports. 27, 8, p. 873–886 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Skeletal muscle morphology, protein synthesis and gene expression in Ehlers Danlos Syndrome

    Nygaard, R. H., Jensen, J. K., Voermans, N. C., Heinemeier, K. M., Schjerling, Peter, Holm, L., Agergaard, J., Mackey, Abigail, Andersen, J. L., Remvig, L. & Kjær, Michael, Aug 2017, In: Journal of Applied Physiology. 123, 2, p. 482-488

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    DNA mismatch repair and its many roles in eukaryotic cells

    Liu, D., Keijzers, G. & Rasmussen, Lene Juel, Jul 2017, In: Mutation Research - Reviews in Mutation Research. 773, p. 174-187 14 p.

    Research output: Contribution to journal › Review › Research › peer-review

  13. Published

    Skeletal muscle morphology and regulatory signalling in endurance-trained and sedentary individuals: The influence of ageing

    Mikkelsen, U. R., Agergaard, J., Couppé, Christian, Grosset, J. F., Karlsen, Anders, Magnusson, Stig Peter, Schjerling, Peter, Kjær, Michael & Mackey, Abigail, Jul 2017, In: Experimental Gerontology. 93, p. 54-67

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    RECQ5 Helicase Cooperates with MUS81 Endonuclease in Processing Stalled Replication Forks at Common Fragile Sites during Mitosis

    Di Marco, S., Hasanova, Z., Kanagaraj, R., Chappidi, N., Altmannova, V., Menon, S., Sedlackova, H., Langhoff, J., Surendranath, K., Hühn, D., Bhowmick, Rahul, Marini, V., Ferrari, S., Hickson, Ian David, Krejci, L. & Janscak, P., 1 Jun 2017, In: Molecular Cell. 66, 5, p. 658-671.e8

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    A simple DNA recombination screening method by RT-PCR as an alternative to Southern blot

    Albers, E., Sbroggiò, M., Martin Gonzalez, Javier, Avram, Alexandra Ioana, Munk, S. & Lopez-Contreras, Andres, Jun 2017, In: Transgenic Research. 26, 3, p. 429-434 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Inflammation relates to resistance training-induced hypertrophy in elderly patients

    Norheim, K. L., Cullum, C. K., Andersen, J. L., Kjær, Michael & Karlsen, Anders, Jun 2017, In: Medicine and Science in Sports and Exercise. 49, 6, p. 1079-1085 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    The lactate receptor HCAR1 promotes neuronal development and protects axons and myelin during hypoglycemia

    Kennedy, L. H., Andersson, K. A., Haugen, O. P., Puchades, M. A., Storm-Mathisen, J., Morland, C., Bergersen, L. H. & Rinholm, J. E., Jun 2017, In: Glia. 65, S1, p. E152-E153 T03-024B.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  18. Published

    Recording, analysis, and interpretation of spreading depolarizations in neurointensive care: Review and recommendations of the COSBID research group

    Dreier, J. P., Fabricius, M., Ayata, C., Sakowitz, O. W., William Shuttleworth, C., Dohmen, C., Graf, R., Vajkoczy, P., Helbok, R., Suzuki, M., Schiefecker, A. J., Major, S., Winkler, M. K., Kang, E-J., Milakara, D., Oliveira-Ferreira, A. I., Reiffurth, C., Revankar, G. S., Sugimoto, K., Dengler, N. F. & 70 others, Hecht, N., Foreman, B., Feyen, B., Kondziella, Daniel, Friberg, C. K., Piilgaard, H., Rosenthal, E. S., Westover, M. B., Maslarova, A., Santos, E., Hertle, D., Sánchez-Porras, R., Jewell, S. L., Balança, B., Platz, J., Hinzman, J. M., Lückl, J., Schoknecht, K., Schöll, M., Drenckhahn, C., Feuerstein, D., Eriksen, N., Horst, V., Bretz, J. S., Jahnke, P., Scheel, M., Bohner, G., Rostrup, E., Pakkenberg, B., Heinemann, U., Claassen, J., Carlson, A. P., Kowoll, C. M., Lublinsky, S., Chassidim, Y., Shelef, I., Friedman, A., Brinker, G., Reiner, M., Kirov, S. A., Andrew, R. D., Farkas, E., Güresir, E., Vatter, H., Chung, L. S., Brennan, K. C., Lieutaud, T., Marinesco, S., Maas, A. I., Sahuquillo, J., Dahlem, M. A., Richter, F., Herreras, O., Boutelle, M. G., Okonkwo, D. O., Bullock, M. R., Witte, O. W., Martus, P., van den Maagdenberg, A. M., Ferrari, M. D., Dijkhuizen, R. M., Shutter, L. A., Andaluz, N., Schulte, A. P., MacVicar, B., Watanabe, T., Woitzik, J., Lauritzen, Martin, Strong, A. J. & Hartings, J. A., May 2017, In: Journal of Cerebral Blood Flow and Metabolism. 37, 5, p. 1595-1625 31 p.

    Research output: Contribution to journal › Review › Research › peer-review

  19. Published

    Predicting the impact of Lynch syndrome-causing missense mutations from structural calculations

    Nielsen, S. V., Stein, Amelie, Dinitzen, A. B., Papaleo, E., Tatham, M. H., Poulsen, E. G., Kassem, M. M., Rasmussen, Lene Juel, Lindorff-Larsen, Kresten & Hartmann-Petersen, Rasmus, 19 Apr 2017, In: PLoS Genetics. 13, 4, 26 p., e1006739.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Characterising the proximal patellar tendon attachment and its relationship to skeletal maturity in adolescent ballet dancers

    Rudavsky, A., Cook, J., Magnusson, Stig Peter, Kjær, Michael & Docking, S., Apr 2017, In: Muscles, Ligaments and Tendons Journal. 7, 2, p. 306-314 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Correction for non-rigid movement artefacts in calcium imaging using local-global optical flow and PCA-based templates

    Brazhe, A., Fordsmann, J. & Lauritzen, Martin, Apr 2017, In: Journal of Cerebral Blood Flow and Metabolism. 37, S1, p. 360-361 PS04-077.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  22. Published

    The Effect of Aging and Mechanical Loading on the Metabolism of Articular Cartilage

    Jørgensen, A. E. M., Kjær, Michael & Heinemeier, K. M., Apr 2017, In: Journal of Rheumatology. 44, 4, p. 410-417

    Research output: Contribution to journal › Review › Research › peer-review

  23. Published

    An advanced glycation endproduct (AGE)-rich diet promotes accumulation of AGEs in Achilles tendon

    Skovgaard, D., Svensson, R. B., Scheijen, J., Eliasson, P., Mogensen, P., Hag, Anne Mette Fisker, Kjær, Michael, Schalkwijk, C. G., Schjerling, P., Magnusson, Stig Peter & Couppé, C., Mar 2017, In: Physiological Reports. 5, 6, 7 p., e13215.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    Connective tissue regeneration in skeletal muscle after eccentric contraction-induced injury

    Mackey, Abigail & Kjær, Michael, Mar 2017, In: Journal of Applied Physiology. 122, 3, p. 533-540 8 p.

    Research output: Contribution to journal › Review › Research › peer-review

  25. Published

    Nanomaterial-induced cell death in pulmonary and hepatic cells following exposure to three different metallic materials: The role of autophagy and apoptosis

    Kermanizadeh, A., Jantzen, K., Ward, M. B., Durhuus, J. A., Rasmussen, Lene Juel, Loft, Steffen & Møller, Peter, Mar 2017, In: Nanotoxicology. 11, 2, p. 184-200 17 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    Tendon collagen synthesis declines with immobilization in elderly humans: no effect of anti-inflammatory medication

    Dideriksen, K., Boesen, A. P., Reitelseder, S., Couppé, C., Svensson, R., Schjerling, P., Magnusson, Stig Peter, Holm, L. & Kjær, Michael, Feb 2017, In: Journal of Applied Physiology. 122, 2, p. 273-282 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    EXO1 (Exonuclease 1)

    Rasmussen, Lene Juel & Keijzers, G., 5 Jan 2017, Encyclopedia of Signaling Molecules . Choi, S. (ed.). New York: Springer, 7 p.

    Research output: Chapter in Book/Report/Conference proceeding › Encyclopedia chapter › Research

  28. Published

    Quantification of cell density in rat Achilles tendon: development and application of a new method

    Couppé, C., Svensson, R. B., Heinemeier, K. M., Thomsen, E. W., Bayer, M. L., Christensen, L., Kjær, Michael, Magnusson, Stig Peter & Schjerling, P., Jan 2017, In: Histochemistry and Cell Biology. 147, 1, p. 97-102 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    A critical role for astrocytes in hypercapnic vasodilation in brain

    Howarth, C., Sutherland, B. A., Choi, H. B., Martin, C., Lind, Barbara Lykke, Khennouf, Lila, LeDue, J. M., Pakan, J. M. P., Ko, R. W., Ellis-Davies, G. C. R., Lauritzen, Martin, Sibson, N. R., Buchan, A. M. & MacVicar, B. A., 2017, In: The Journal of Neuroscience. 37, 9, p. 2403-2414 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    A novel TPR-BEN domain interaction mediates PICH-BEND3 association

    Pitchai, G. P., Kaulich, M., Bizard, A. H., Mesa, Pablo, Yao, Q., Sarlos, K., Streicher, W. W., Nigg, E. A., Montoya, Guillermo & Hickson, Ian David, 2017, In: Nucleic Acids Research. 19, 2, p. 11413–11424

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Published

    Acute inactivation of the replicative helicase in human cells triggers MCM8-9-dependent DNA synthesis

    Natsume, T., Nishimura, K., Minocherhomji, S., Bhowmick, Rahul, Hickson, Ian David & Kanemaki, M. T., 2017, In: Genes & Development. 31, 8, p. 816-829 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. Published

    Biochemical and Mass Spectrometry-Based Approaches to Profile SUMOylation in Human Cells

    Kessler, B. M., Bursomanno, S., McGouran, J. F., Hickson, Ian David & Liu, Ying, 2017, Activity-Based Proteomics: Methods and Protocols. Overkleeft, H. S. & Florea, B. I. (eds.). Humana Press, Vol. 1491. p. 131-144 14 p. (Methods in Molecular Biology, Vol. 1491).

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  33. Published

    Bioenergetic Changes during Differentiation of Human Embryonic Stem Cells along the Hepatic Lineage

    Hopkinson, B. M., Desler, Claus, Kalisz, M., Vestentoft, P. S., Rasmussen, Lene Juel & Bisgaard, Hanne Cathrine, 2017, In: Oxidative Medicine and Cellular Longevity. 2017, 11 p., 5080128.

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Published

    Cockayne syndrome: Clinical features, model systems and pathways

    Karikkineth, A. C., Scheibye-Knudsen, Morten, Fivenson, E., Croteau, D. L. & Bohr, Vilhelm, 2017, In: Ageing Research Reviews. 33, p. 3-17

    Research output: Contribution to journal › Review › Research › peer-review

  35. Published

    Disturbed mitochondrial function restricts glutamate uptake in the human Müller glia cell line, MIO-M1

    Vohra, Rupali, Gurubaran, I. S., Henriksen, U., Bergersen, L. H., Rasmussen, Lene Juel, Desler, C., Jensen, Dorte Skytt & Kolko, Miriam, 2017, In: Mitochondrion. 36, p. 52-59

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    Exercise induces cerebral VEGF and angiogenesis via the lactate receptor HCAR1

    Morland, C., Andersson, K. A., Haugen, O. P., Hadzic, A., Kleppa, L., Gille, A., Rinholm, J. E., Palibrk, V., Diget, E. H., Kennedy, L. H., Stolen, T., Hennestad, E., Moldestad, O., Cai, Y., Puchades, M., Offermanns, S., Vervaeke, K., Bjoras, M., Wisloff, U., Storm-Mathisen, J. & 1 others, Bergersen, L. H., 2017, In: Nature Communications. 8, 9 p., 15557.

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Published

    Genomic and functional integrity of the hematopoietic system requires tolerance of oxidative DNA lesions

    Martín-Pardillos, A., Tsaalbi-Shtylik, A., Chen, S., Lazare, S., Van Os, R. P., Dethmers-Ausema, A., Fakouri, N. B., Bosshard, M., Aprigliano, R., Van Loon, B., Salvatori, D. C. F., Hashimoto, K., Van Der Spek, C. D., Moriya, M., Rasmussen, Lene Juel, De Haan, G., Raaijmakers, M. H. G. P. & De Wind, N., 2017, In: Blood. 130, 13, p. 1523-1534 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. Published

    Human skeletal muscle fibroblasts stimulate in vitro myogenesis and in vivo muscle regeneration

    Mackey, Abigail, Magnan, M., Chazaud, B. & Kjær, Michael, 2017, In: The Journal of Physiology. 595, 15, p. 5115-5127 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. Published

    Impact of GH administration on athletic performance in healthy young adults: A systematic review and meta-analysis of placebo-controlled trials

    Hermansen, K., Bengtsen, M., Kjær, Michael, Vestergaard, P. & Jørgensen, J. O. L., 2017, In: Growth Hormone & I G F Research. 34, p. 38-44

    Research output: Contribution to journal › Review › Research › peer-review

  40. Published

    Improved Functional Performance in Geriatric Patients During Hospital Stay

    Karlsen, Anders, Loeb, M. R., Andersen, K. B., Joergensen, K. J., Scheel, F. U., Turtumoeygard, I. F., Perez, A. L. R., Kjær, Michael & Beyer, N., 2017, In: American Journal of Physical Medicine and Rehabilitation. 96, 5, p. e78-e84

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. Published

    Improved skeletal muscle mass and strength after heavy strength training in very old individuals

    Bechshøft, R. L., Malmgaard-Clausen, N. M., Gliese, B., Beyer, N., Mackey, Abigail, Andersen, J. L., Kjær, Michael & Holm, L., 2017, In: Experimental Gerontology. 92, p. 96-105 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. Published

    Interneuron Deficit Associates Attenuated Network Synchronization to Mismatch of Energy Supply and Demand in Aging Mouse Brains

    Jessen, S. B., Mathiesen, C., Lind, Barbara Lykke & Lauritzen, Martin, 2017, In: Cerebral Cortex. 27, 1, p. 646-659

    Research output: Contribution to journal › Journal article › Research › peer-review

  43. Published

    Involvement of the DNA mismatch repair system in cisplatin sensitivity of testicular germ cell tumours

    Rudolph, C., Melau, C., Nielsen, J. E., Jensen, K. V., Liu, D., Pena-Diaz, J., Meyts, E. R., Rasmussen, Lene Juel & Jorgensen, A., 2017, In: Cellular Oncology. 40, 4, p. 341-355

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Published

    Knotty Problems during Mitosis: Mechanistic Insight into the Processing of Ultrafine DNA Bridges in Anaphase

    Sarlós, K., Biebricher, A., Petermann, E. J. G., Wuite, G. J. L. & Hickson, Ian David, 2017, In: Cold Spring Harbor Laboratory. Symposia on Quantitative Biology. 82, p. 187-195

    Research output: Contribution to journal › Journal article › Research › peer-review

  45. Published

    Mitophagy in neurodegeneration and aging

    Fivenson, E. M., Lautrup, S., Sun, N., Scheibye-Knudsen, Morten, Stevnsner, T., Nilsen, H., Bohr, Vilhelm & Fang, E. F., 2017, In: Neurochemistry International. 109, p. 202-209

    Research output: Contribution to journal › Review › Research › peer-review

  46. Published

    Multi-modal assessment of neurovascular coupling during cerebral ischaemia and reperfusion using remote middle cerebral artery occlusion

    Sutherland, B. A., Fordsmann, J. C., Martin, C., Neuhaus, A. A., Witgen, B. M., Hansen, H. P., Lønstrup, M., Couch, Y., Sibson, N. R., Lauritzen, Martin & Buchan, A. M., 2017, In: Journal of Cerebral Blood Flow and Metabolism. 37, 7, p. 2494-2508 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. Published

    Muscle power is an important measure to detect deficits in muscle function in hip osteoarthritis: a cross-sectional study

    Bieler, T., Magnusson, Stig Peter, Christensen, H. E., Kjær, Michael & Beyer, N., 2017, In: Disability and Rehabilitation. 39, 14, p. 1414-1421

    Research output: Contribution to journal › Journal article › Research › peer-review

  48. Published

    Myosin content of single muscle fibers following short-term disuse and active recovery in young and old healthy men

    Hvid, L. G., Brocca, L., Ørtenblad, N., Suetta, Charlotte, Aagaard, P., Kjær, Michael, Bottinelli, R. & Pellegrino, M. A., 2017, In: Experimental Gerontology. 87, Part A, p. 100-107

    Research output: Contribution to journal › Journal article › Research › peer-review

  49. Published

    No Change in Lower Limb Extension Power during a Hospital Stay in Geriatric Patients, Despite Improved Functional Level

    Karlsen, Anders, Loeb, M. R., Turtumoeygard, I. F., Scheel, F. U., Andersen, K. B., Joergensen, K. J., Rodriguez Perez, A. L., Kjær, Michael & Beyer, N., 2017, In: Annals of Gerontology and Geriatric Research . 4, 1, 7 p., 1046.

    Research output: Contribution to journal › Journal article › Research › peer-review

  50. Published

    PSD-95 uncoupling from NMDA receptors by Tat-N-dimer ameliorates neuronal depolarization in cortical spreading depression

    Kucharz, Krzysztof, Søndergaard Rasmussen, I., Bach, Anders, Strømgaard, Kristian & Lauritzen, Martin, 2017, In: Journal of Cerebral Blood Flow and Metabolism. 37, 5, p. 1820-1828

    Research output: Contribution to journal › Journal article › Research › peer-review

  51. Published

    Potential biomarkers of DNA replication stress in cancer

    Ren, L., Chen, L., Wu, Wei, Garribba, L., Tian, H., Liu, Z., Vogel, Ivan, Li, C., Hickson, Ian David & Liu, Ying, 2017, In: OncoTarget. 8, 23, p. 36996-37008 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  52. Published

    Proteomics Reveals Global Regulation of Protein SUMOylation by ATM and ATR Kinases during Replication Stress

    Munk, S., Sigurðsson, J. O., Xiao, Z., Batth, Tanveer Singh, Franciosa, Giulia, von Stechow, L., Lopez-Contreras, Andres, Vertegaal, A. C. O. & Olsen, Jesper Velgaard, 2017, In: Cell Reports. 21, 2, p. 546-558 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  53. Published

    Rev1 contributes to proper mitochondrial function via the PARP-NAD(+)-SIRT1-PGC1 alpha axis

    Fakouri, N. B., Durhuus, J. A., Regnell, C. E., Angleys, M., Desler, Claus, Hasan-Olive, M., Martin-Pardillos, A., Tsaalbi-Shtylik, A., Thomsen, Kirsten Joan, Lauritzen, Martin, Bohr, Vilhelm, de Wind, N., Bergersen, L. H. & Rasmussen, Lene Juel, 2017, In: Scientific Reports. 7, 14 p., 12480.

    Research output: Contribution to journal › Journal article › Research › peer-review

  54. Published

    Simvastatin and atorvastatin reduce the mechanical properties of tendon constructs in vitro and introduce catabolic changes in the gene expression pattern

    Eliasson, P., Svensson, R. B., Giannopoulos, A., Eismark, C., Kjær, Michael, Schjerling, P. & Heinemeier, K. M., 2017, In: PLOS ONE. 12, 3, 16 p., e0172797.

    Research output: Contribution to journal › Journal article › Research › peer-review

  55. Published

    Stalled replication forks generate a distinct mutational signature in yeast

    Larsen, N. B., Liberti, S. E., Vogel, Ivan, Jorgensen, S. W., Hickson, Ian David & Mankouri, H. W., 2017, In: Proceedings of the National Academy of Sciences of the United States of America. 114, 36, p. 9665-9670

    Research output: Contribution to journal › Journal article › Research › peer-review

  56. Published

    Sub-Clinical Cognitive Decline and Resting Cerebral Blood Flow in Middle Aged Men

    Henriksen, O. M., Hansen, N. L., Osler, Merete, Mortensen, Erik Lykke, Hallam, D. M., Pedersen, E. T., Chappell, M., Lauritzen, Martin & Rostrup, E., 2017, In: PLOS ONE. 12, 1, 15 p., e0169912.

    Research output: Contribution to journal › Journal article › Research › peer-review

  57. Published

    The "enemies within": regions of the genome that are inherently difficult to replicate

    Bhowmick, Rahul & Hickson, Ian David, 2017, In: F1000Research. 6, 7 p., 666.

    Research output: Contribution to journal › Review › Research › peer-review

  58. Published

    The breaking and making of healthy adult human skeletal muscle in vivo

    Mackey, Abigail & Kjær, Michael, 2017, In: Skeletal Muscle. 7, 18 p., 24.

    Research output: Contribution to journal › Journal article › Research › peer-review

  59. Published

    Tomatidine enhances lifespan and healthspan in C. elegans through mitophagy induction via the SKN-1/Nrf2 pathway

    Fang, E. F., Waltz, T. B., Kassahun, H., Lu, Q., Kerr, J. S., Morevati, M., Fivenson, E. M., Wollman, B. N., Marosi, K., Wilson, M. A., Iser, W. B., Eckley, D. M., Zhang, Y., Lehrmann, E., Goldberg, I. G., Scheibye-Knudsen, Morten, Mattson, M. P., Nilsen, H., Bohr, Vilhelm & Becker, K. G., 2017, In: Scientific Reports. 7, 46208.

    Research output: Contribution to journal › Journal article › Research › peer-review

  60. Published

    Visual steady state in relation to age and cognitive function

    Horwitz, A., Dyhr Thomsen, M., Wiegand, I., Horwitz, H., Klemp, Marc Patrick Brag, Nikolic, M., Rask, L., Lauritzen, Martin & Benedek, Krisztina, 2017, In: PLOS ONE. 12, 2, 23 p., e0171859.

    Research output: Contribution to journal › Journal article › Research › peer-review

  61. 2016
  62. Published

    RAD52 Facilitates Mitotic DNA Synthesis Following Replication Stress

    Bhowmick, Rahul, Minocherhomji, S. & Hickson, Ian David, 15 Dec 2016, In: Molecular Cell. 64, 6, p. 1117-1126 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  63. Published

    Cognitive Change during the Life Course and Leukocyte Telomere Length in Late Middle-Aged Men

    Rask, L., Bendix, L., Harbo, M., Fagerlund, Birgitte, Mortensen, Erik Lykke, Lauritzen, Martin & Osler, Merete, 9 Dec 2016, In: Frontiers in Aging Neuroscience. 8, 7 p., 300.

    Research output: Contribution to journal › Journal article › Research › peer-review

  64. Published

    Effect of aging and exercise on the tendon

    Svensson, R. B., Heinemeier, K. M., Couppé, Christian, Kjær, Michael & Magnusson, Stig Peter, 1 Dec 2016, In: Journal of Applied Physiology. 121, 6, p. 1237-1246 10 p.

    Research output: Contribution to journal › Review › Research › peer-review

  65. Published

    3-Hydroxybutyrate regulates energy metabolism and induces BDNF expression in cerebral cortical neurons

    Marosi, K., Kim, S. W., Moehl, K., Scheibye-Knudsen, Morten, Cheng, A., Cutler, R., Camandola, S. & Mattson, M. P., Dec 2016, In: Journal of Neurochemistry. 139, 5, p. 769-781 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  66. Published

    A Novel Rrm3 Function in Restricting DNA Replication via an Orc5-Binding Domain Is Genetically Separable from Rrm3 Function as an ATPase/Helicase in Facilitating Fork Progression

    Syed, S., Desler, Claus, Rasmussen, Lene Juel & Schmidt, K. H., Dec 2016, In: P L o S Genetics. 12, 12, 28 p., e1006451.

    Research output: Contribution to journal › Journal article › Research › peer-review

  67. Published

    A ketogenic diet accelerates neurodegeneration in mice with induced mitochondrial DNA toxicity in the forebrain

    Lauritzen, K. H., Hasan-Olive, M. M., Regnell, C. E., Kleppa, L., Scheibye-Knudsen, Morten, Gjedde, Albert, Klungland, A., Bohr, Vilhelm, Storm-Mathisen, J. & Bergersen, L. H., Dec 2016, In: Neurobiology of Aging. 48, p. 34-47

    Research output: Contribution to journal › Journal article › Research › peer-review

  68. Published

    Interventions for age-related diseases: Shifting the paradigm

    Figueira, I., Fernandes, A., Mladenovic Djordjevic, A., Lopez-Contreras, Andres, Henriques, C. M., Selman, C., Ferreiro, E., Gonos, E. S., Trejo, J. L., Misra, J., Rasmussen, Lene Juel, Xapelli, S., Ellam, T. & Bellantuono, I., Dec 2016, In: Mechanisms of Ageing and Development. 160, p. 69-92 24 p.

    Research output: Contribution to journal › Review › Research › peer-review

  69. Published

    Isometric abdominal wall muscle strength assessment in individuals with incisional hernia: a prospective reliability study

    Jensen, K. K., Kjær, Michael & Jørgensen, Lars Nannestad, Dec 2016, In: Hernia. 20, 6, p. 831-837

    Research output: Contribution to journal › Journal article › Research › peer-review

  70. Published

    Physical activity as intervention for age-related loss of muscle mass and function: protocol for a randomised controlled trial (the LISA study)

    Eriksen, C. S., Garde, Ellen, Reislev, N. L., Wimmelmann, Cathrine Lawaetz, Bieler, T., Ziegler, A. K., Gylling, A. T., Dideriksen, K. J., Siebner, Hartwig Roman, Mortensen, Erik Lykke & Kjær, Michael, Dec 2016, In: B M J Open. 6, 12, p. 1-13 13 p., e012951.

    Research output: Contribution to journal › Journal article › Research › peer-review

  71. Published

    DNA Damage Signaling Instructs Polyploid Macrophage Fate in Granulomas

    Herrtwich, L., Nanda, I., Evangelou, K., Nikolova, T., Horn, V., Sagar, Erny, D., Stefanowski, J., Rogell, L., Klein, C., Gharun, K., Follo, M., Seidl, M., Kremer, B., Muenke, N., Senges, J., Fliegauf, M., Aschman, T., Pfeifer, D., Sarrazin, S. & 18 others, Sieweke, M. H., Wagner, D., Dierks, C., Haaf, T., Ness, T., Zaiss, M. M., Voll, R. E., Deshmukh, S. D., Prinz, M., Goldmann, T., Hoelscher, C., Hauser, A. E., Lopez-Contreras, Andres, Gruen, D., Gorgoulis, V., Diefenbach, A., Henneke, P. & Triantafyllopoulou, A., 17 Nov 2016, In: Cell. 167, 5, p. 1264–1280.e18

    Research output: Contribution to journal › Journal article › Research › peer-review

  72. Published

    SCAI promotes DNA double-strand break repair in distinct chromosomal contexts

    Hansen, R. K., Mund, A., Poulsen, S. L., Sandoval, M., Klement, K., Tsouroula, K., Tollenaere, M. A. X., Räschle, M., Soria, R., Offermanns, S., Worzfeld, T., Grosse, R., Brandt, D. T., Rozell, B., Mann, M., Cole, F., Soutoglou, E., Goodarzi, A. A., Daniel, J. A., Mailand, N. & 1 others, Bekker-Jensen, Simon Holst, 7 Nov 2016, In: Nature Cell Biology. 18, 12, p. 1357–1366

    Research output: Contribution to journal › Letter › Research › peer-review

  73. Published

    Cockayne syndrome group A and B proteins converge on transcription-linked resolution of non-B DNA

    Scheibye-Knudsen, M., Tseng, A., Jensen, M. B., Scheibye-Alsing, K., Fang, E. F., Iyama, T., Bharti, S. K., Marosi, K., Froetscher, L., Kassahun, H., Eckley, D. M., Maul, R. W., Bastian, P., De, S., Ghosh, S., Nilsen, H., Goldberg, I. G., Mattson, M. P., Wilson, D. M. . III., Brosh, R. M. . J. & 2 others, Gorospe, M. & Bohr, Vilhelm, 1 Nov 2016, In: National Academy of Sciences. Proceedings. 113, 44, p. 12502-12507

    Research output: Contribution to journal › Journal article › Research › peer-review

  74. Published

    Activation of the ATR kinase by the RPA-binding protein ETAA1

    Haahr, Peter Thorlund, Hoffmann, Saskia, Tollenaere, M. A. X., Ho, T., Toledo Lazaro, L. I., Mann, Matthias, Bekker-Jensen, Simon Holst, Räschle, M. & Mailand, Niels, Nov 2016, In: Nature Cell Biology. 18, 11, p. 1196–1207

    Research output: Contribution to journal › Journal article › Research › peer-review

  75. Published

    Neurodegeneration in Accelerated Aging

    Scheibye-Knudsen, Morten, Nov 2016, In: Danish Medical Journal. 63, 11, 21 p., B5308.

    Research output: Contribution to journal › Review › Research › peer-review

  76. Published

    PICH promotes mitotic chromosome segregation: Identification of a novel role in rDNA disjunction

    Nielsen, Christian Friberg & Hickson, Ian David, 17 Oct 2016, In: Cell Cycle. 15, 20, p. 2704-2711 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  77. Published

    NAD(+) Replenishment Improves Lifespan and Healthspan in Ataxia Telangiectasia Models via Mitophagy and DNA Repair

    Fang, E. F., Kassahun, H., Croteau, D. L., Scheibye-Knudsen, M., Marosi, K., Lu, H., Shamanna, R. A., Kalyanasundaram, S., Bollineni, R. C., Wilson, M. A., Iser, W. B., Wollman, B. N., Morevati, M., Li, J., Kerr, J. S., Lu, Q., Waltz, T. B., Tian, J., Sinclair, D. A., Mattson, M. P. & 2 others, Nilsen, H. & Bohr, Vilhelm, 11 Oct 2016, In: Cell Metabolism. 24, 4, p. 566-581 16 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  78. Published

    Rad54 and Mus81 cooperation promotes DNA damage repair and restrains chromosome missegregation

    Ghamrasni, S. E., Cardoso, R., Li, L., Guturi, K. K. N., Bjerregaard, Victoria Alexandra, Liu, Ying, Venkatesan, S., Hande, M. P., Henderson, J. T., Sanchez, O., Hickson, Ian David, Hakem, A. & Hakem, R., 15 Sep 2016, In: Oncogene. 35, 37, p. 4836-4845 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  79. Published

    In response: Gamma oscillations or spikes?

    Benedek, Krisztina & Lauritzen, Martin, Sep 2016, In: Epilepsia. 57, 9, p. 1524–1525 2 p.

    Research output: Contribution to journal › Comment/debate › Research › peer-review

  80. Published

    Ruptured human Achilles tendon has elevated metabolic activity up to 1 year after repair

    Eliasson, P., Couppé, C., Lonsdale, M., Svensson, R. B., Neergaard, C., Kjær, Michael, Friberg, L. & Magnusson, Stig Peter, Sep 2016, In: European Journal of Nuclear Medicine and Molecular Imaging. 43, 10, p. 1868-77 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  81. Published

    Skeletal muscle adaptation to immobilization and subsequent retraining in elderly men: No effect of anti-inflammatory medication

    Dideriksen, K., Boesen, A. P., Kristiansen, J. F., Magnusson, Stig Peter, Schjerling, Peter, Holm, L. & Kjær, Michael, Sep 2016, In: Experimental Gerontology. 82, p. 8-18 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  82. Published

    Efficacy of ATR inhibitors as single agents in Ewing sarcoma

    Nieto-Soler, M., Morgado-Palacin, I., Lafarga, V., Lecona, E., Murga, M., Callen, E., Azorin, D., Alonso, J., Lopez-Contreras, Andres, Nussenzweig, A. & Fernandez-Capetillo, O., 26 Aug 2016, In: OncoTarget. 7, 37, p. 58759-58767

    Research output: Contribution to journal › Journal article › Research › peer-review

  83. Published

    Exonuclease 1 and its versatile roles in DNA repair

    Keijzers, G., Liu, D. & Rasmussen, Lene Juel, 5 Aug 2016, In: Critical Reviews in Biochemistry and Molecular Biology. 51, 6, p. 440–451 12 p.

    Research output: Contribution to journal › Review › Research › peer-review

  84. Published

    Activity-Dependent Calcium, Oxygen, and Vascular Responses in a Mouse Model of Familial Hemiplegic Migraine Type 1

    Khennouf, Lila, Gesslein, B., Lind, Barbara Lykke, van den Maagdenberg, A. M. J. M. & Lauritzen, Martin, Aug 2016, In: Annals of Neurology. 80, 2, p. 219-232

    Research output: Contribution to journal › Journal article › Research › peer-review

  85. Published

    Characterization of the NTPR and BD1 interacting domains of the human PICH-BEND3 complex

    Pitchai, G. P., Hickson, Ian David, Streicher, W., Montoya, Guillermo & Mesa, Pablo, Aug 2016, In: Acta Crystallographica. Section F: Structural Biology and Crystallization Communications Online. 72, 8, p. 646-651 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  86. Published

    Sex Hormones and Tendon

    Hansen, M. & Kjær, Michael, Aug 2016, Metabolic influences on risk for tendon disorders. Springer, Vol. 920. p. 139-149 11 p. (Advances in Experimental Medicine and Biology).

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  87. Published

    Radiocarbon dating reveals minimal collagen turnover in both healthy and osteoarthritic human cartilage

    Heinemeier, K. M., Schjerling, P., Heinemeier, J., Møller, M. B., Krogsgaard, Michael R., Grum-Schwensen, T., Petersen, Michael Mørk & Kjær, Michael, 6 Jul 2016, In: Science Translational Medicine. 8, 346, 346ra90.

    Research output: Contribution to journal › Journal article › Research › peer-review

  88. Published

    H4K20me0 marks post-replicative chromatin and recruits the TONSL–MMS22L DNA repair complex

    Saredi, G., Huang, H., Hammond, Colin, Alabert, C., Bekker-Jensen, Simon Holst, Forne, I., Reveron-Gomez, Nazaret, Foster, B. M., Mlejnkova, L., Bartke, T., Cejka, P., Mailand, Niels, Imhof, A., Patel, D. J. & Groth, Anja, 30 Jun 2016, In: Nature. 534, 7609, p. 714-8 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  89. Published

    RECQL4 Promotes DNA End Resection in Repair of DNA Double-Strand Breaks

    Lu, H., Shamanna, R. A., Keijzers, G., Anand, R., Rasmussen, Lene Juel, Cejka, P., Croteau, D. L. & Bohr, Vilhelm, 28 Jun 2016, In: Cell Reports. 16, 1, p. 161-173 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  90. Published

    No additional effect of different types of physical activity on 10-hour muscle protein synthesis in elderly men on a controlled energy- and protein-sufficient diet

    Bulow, J., Agergaard, J., Kjær, Michael, Holm, L. & Reitelseder, S., 15 Jun 2016, In: Experimental Gerontology. 79, p. 16-25

    Research output: Contribution to journal › Journal article › Research › peer-review

  91. Published

    Acquired Localized Cutis Laxa due to Increased Elastin Turnover

    Nygaard, R. H., Maynard, S., Schjerling, P., Kjær, M., Qvortrup, Klaus, Bohr, Vilhelm, Rasmussen, Lene Juel, Jemec, Gregor & Heidenheim, M., 14 Jun 2016, In: Case Reports in Dermatology. 8, 1, p. 42-51 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  92. Published

    Effects of Sex, Strain, and Energy Intake on Hallmarks of Aging in Mice

    Mitchell, S. J., Madrigal-Matute, J., Scheibye-Knudsen, M., Fang, E., Aon, M., Gonzalez-Reyes, J. A., Cortassa, S., Kaushik, S., Gonzalez-Freire, M., Patel, B., Wahl, D., Ali, A., Calvo-Rubio, M., Buron, M. I., Guiterrez, V., Ward, T. M., Palacios, H. H., Cai, H., Frederick, D. W., Hine, C. & 27 others, Broeskamp, F., Habering, L., Dawson, J., Beasley, T. M., Wan, J., Ikeno, Y., Hubbard, G., Becker, K. G., Zhang, Y., Bohr, V. A., Longo, D. L., Navas, P., Ferrucci, L., Sinclair, D. A., Cohen, P., Egan, J. M., Mitchell, J. R., Baur, J. A., Allison, D. B., Anson, R. M., Villalba, J. M., Madeo, F., Cuervo, A. M., Pearson, K. J., Ingram, D. K., Bernier, M. & de Cabo, R., 14 Jun 2016, In: Cell Metabolism. 23, 6, p. 1093-1112

    Research output: Contribution to journal › Journal article › Research › peer-review

  93. Published

    Structural Analysis of a Complex between Small Ubiquitin-like Modifier 1 (SUMO1) and the ZZ Domain of CREB-binding Protein (CBP/p300) Reveals a New Interaction Surface on SUMO

    Diehl, C., Akke, M., Bekker-Jensen, Simon Holst, Mailand, Niels, Streicher, W. & Wikström, M., 10 Jun 2016, In: Journal of Biological Chemistry. 291, 24, p. 12658-12672 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  94. Published

    Lactate Transport and Receptor Actions in Retina: Potential Roles in Retinal Function and Disease

    Kolko, Miriam, Vosborg, F., Henriksen, J. U. L., Hasan-Olive, M. M., Diget, E. H., Vohra, Rupali, Gurubaran, I. S., Gjedde, Albert, Mariga, S. T., Jensen, Dorte Skytt, Utheim, T. P., Storm-Mathisen, J. & Bergersen, L. H., 1 Jun 2016, In: Neurochemical Research. 41, 6, p. 1229-1236

    Research output: Contribution to journal › Journal article › Research › peer-review

  95. Published

    ATP induce intracellular calcium rises in cultures of primary brain pericytes

    Jensen, S. H., Helms, H. C. C., Jessen, S. B., Lauritzen, Martin, Waagepetersen, Helle S. & Larsen, Birger Brodin, Jun 2016.

    Research output: Contribution to conference › Conference abstract for conference › Research › peer-review

  96. Published

    Regulation of DNA double-strand break repair by ubiquitin and ubiquitin-like modifiers

    Schwertman, P., Bekker-Jensen, Simon Holst & Mailand, Niels, Jun 2016, In: Nature Reviews. Molecular Cell Biology. 17, 6, p. 379-94 16 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  97. Published

    Local trauma in human patellar tendon leads to widespread changes in the tendon gene expression

    Heinemeier, K. M., Lorentzen, M. P., Kildevang Jensen, J., Schjerling, P., Sennes, O., Narici, M. & Kjær, Michael, 1 May 2016, In: Journal of Applied Physiology. 120, 9, p. 1000-1010 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  98. Published

    Neocortical gamma oscillations in idiopathic generalized epilepsy

    Benedek, K., Berenyi, A., Gombkoto, P., Piilgaard, H. & Lauritzen, Martin, May 2016, In: Epilepsia. 57, 5, p. 796-804 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  99. Published

    Oxidative Stress-Induced Dysfunction of Muller Cells During Starvation

    Toft-Kehler, A. K., Gurubaran, I. S., Desler, Claus, Rasmussen, Lene Juel, Jensen, Dorte Skytt & Kolko, Miriam, May 2016, In: Investigative Ophthalmology & Visual Science. 57, 6, p. 2721-2728

    Research output: Contribution to journal › Journal article › Research › peer-review

  100. Published

    USP7 is a SUMO deubiquitinase essential for DNA replication

    Lecona, E., Rodriguez-Acebes, S., Specks, J., Lopez-Contreras, Andres, Ruppen, I., Murga, M., Muñoz, J., Mendez, J. & Fernandez-Capetillo, O., 23 Apr 2016, In: Nature Structural and Molecular Biology. 23, 4, p. 270-277 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  101. Published

    Activation of satellite cells and the regeneration of human skeletal muscle are expedited by ingestion of nonsteroidal anti-inflammatory medication

    Mackey, Abigail, Rasmussen, L. K., Kadi, F., Schjerling, Peter, Helmark, I. C., Ponsot, E., Aagaard, P., Durigan, J. L. Q. & Kjær, Michael, 2 Mar 2016, In: FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 30, 6, p. 2266-2281

    Research output: Contribution to journal › Journal article › Research › peer-review

  102. Published

    Behavioural effects of high fat diet in a mutant mouse model for the schizophrenia risk gene neuregulin 1: High fat diet in schizophrenia mouse model

    Holm-hansen, S., Low, J. K., Zieba, J., Gjedde, Albert, Bergersen, L. H. & Karl, T., 1 Mar 2016, In: Genes, Brain and Behavior. 15, 3, p. 295-304

    Research output: Contribution to journal › Journal article › Research › peer-review

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