- 2020
- Published
Protecting the Aging Genome
Petr, Michael Angelo, Tulika, T., Carmona Marin, Lina Maria & Scheibye-Knudsen, Morten, 2020, In: Trends in Cell Biology. 30, 2, p. 117-132 16 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Proteomics identifies differences in fibrotic potential of extracellular vesicles from human tendon and muscle fibroblasts
Yeung, C. C., Schoof, E. M., Tamáš, M., Mackey, Abigail & Kjær, Michael, 2020, In: Cell Communication and Signaling. 18, 1, 15 p., 177.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
RTEL1 suppresses G-quadruplex-associated R-loops at difficult-to-replicate loci in the human genome
Wu, Wei, Bhowmick, Rahul, Vogel, Ivan, Özer, Ö., Ghisays, F., Thakur, R. S., Sanchez de Leon, E., Richter, P. H., Ren, L., Petrini, J. H., Hickson, Ian David & Liu, Ying, 2020, In: Nature Structural & Molecular Biology. 27, 5, p. 424-437 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Regional collagen turnover and composition of the human patellar tendon
Zhang, C., Couppé, Christian, Scheijen, J. L. J. M., Schalkwijk, C. G., Kjær, Michael, Magnusson, Stig Peter & Svensson, R. B., 2020, In: Journal of Applied Physiology. 128, 4, p. 884-891Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Regional differences in turnover, composition, and mechanics of the porcine flexor tendon
Zhang, C., Svensson, R. B., Couppé, Christian, Schjerling, P., Skovgaard, D., Kjær, Michael & Magnusson, Stig Peter, 2020, In: Connective Tissue Research. 61, 5, p. 475-484Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Replication Stress Induces ATR/CHK1-Dependent Nonrandom Segregation of Damaged Chromosomes
Xing, M., Zhang, F., Liao, H., Chen, S., Che, L., Wang, X., Bao, Z., Ji, F., Chen, G., Zhang, H., Li, W., Chen, Z., Liu, Ying, Hickson, Ian David, Shen, H. & Ying, S., 2020, In: Molecular Cell. 78, 4, p. 714-724.e5Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Senescent cells promote tissue NAD+ decline during ageing via the activation of CD38+ macrophages
Covarrubias, A. J., Kale, A., Perrone, R., Lopez-Dominguez, J. A., Pisco, A. O., Kasler, H. G., Schmidt, M. S., Heckenbach, I., Kwok, R., Wiley, C. D., Wong, H. S., Gibbs, E., Iyer, S. S., Basisty, N., Wu, Q., Kim, I. J., Silva, E., Vitangcol, K., Shin, K. O., Lee, Y. M. & 11 others, , 2020, In: Nature Metabolism. 2, 11, p. 1265-1283 19 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Simvastatin improves mitochondrial respiration in peripheral blood cells
Durhuus, J. A., Hansson, Svenja, Morville, T., Kuhlman, A. B., Dohlmann, T. L., Larsen, Steen, Helge, Jørn Wulff, Angleys, M., Muniesa-Vargas, A., Bundgaard, J. R., Hickson, Ian David, Dela, Flemming, Desler, Claus & Rasmussen, Lene Juel, 2020, In: Scientific Reports. 10, 1, 17012.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Spatial Transcriptomics Reveals Genes Associated with Dysregulated Mitochondrial Functions and Stress Signaling in Alzheimer Disease
Navarro, J. F., Croteau, D. L., Jurek, A., Andrusivova, Z., Yang, B., Wang, Y., Ogedegbe, B., Riaz, T., Støen, M., Desler, Claus, Rasmussen, Lene Juel, Tønjum, T., Galas, M. C., Lundeberg, J. & Bohr, Vilhelm, 2020, In: iScience. 23, 10, 42 p., 101556.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Supraphysiological protection from replication stress does not extend mammalian lifespan
Albers, E., Avram, Alexandra Ioana, Sbroggio, M., Fernandez-Capetillo, O. & Lopez-Contreras, Andres, 2020, In: Aging. 12, 7, p. 5612-5624 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
TIP60 in aging and neurodegeneration
Li, Zhiquan & Rasmussen, Lene Juel, 2020, In: Ageing Research Reviews. 64, 101195.Research output: Contribution to journal › Review › Research › peer-review
- Published
The NAD+-mitophagy axis in healthy longevity and in artificial intelligence-based clinical applications
Aman, Y., Frank, J., Lautrup, S. H., Matysek, A., Niu, Z., Yang, G., Shi, L., Bergersen, L. H., Storm-Mathisen, J., Rasmussen, Lene Juel, Bohr, Vilhelm, Nilsen, H. & Fang, E. F., 2020, In: Mechanisms of Ageing and Development. 185, 111194.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The ZGRF1 Helicase Promotes Recombinational Repair of Replication-Blocking DNA Damage in Human Cells
Brannvoll, A., Xue, X., Kwon, Y., Kompocholi, Smaragda, Simonsen, Anne Katrine Wrist, Bagge, Keerthana Stine Viswalingam, Gonzalez, L., Hickson, Ian David, Østergaard, Vibe Hallundbæk, Mankouri, H. W., Sung, P. & Lisby, Michael, 2020, In: Cell Reports. 32, 1, 25 p., 107849.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The effect of 4 months exercise training on systemic biomarkers of cartilage and bone turnover in hip osteoarthritis patients
Ellegaard, M., Bieler, T., Beyer, N., Kjær, Michael & Jørgensen, Niklas Rye, 2020, In: Translational Sports Medicine. 3, 1, p. 16-25Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The influence of prolonged strength training upon muscle and fat in healthy and chronically diseased older adults
Gylling, A. T., Eriksen, C. S., Garde, Ellen, Wimmelmann, Cathrine Lawaetz, Reislev, N. L., Bieler, T., Ziegler, A. K., Andersen, K. W., Bauer, C., Dideriksen, K., Bækgaard, M., Mertz, K. H., Bayer, M. L., Bloch-Ibenfeldt, M., Boraxbekk, CJ, Siebner, Hartwig Roman, Mortensen, Erik Lykke & Kjær, Michael, 2020, In: Experimental Gerontology. 136, 110939.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The many lives of type IA topoisomerases
Bizard, A. H. & Hickson, Ian David, 2020, In: Journal of Biological Chemistry. 295, 20, p. 7138-7153 16 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
The prevention and resolution of DNA replication–transcription conflicts in eukaryotic cells
Wu, Wei, Hickson, Ian David & Liu, Ying, 2020, In: Genome Instability & Disease. 1, 3, p. 114–128 15 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Tumour predisposition and cancer syndromes as models to study gene–environment interactions
Carbone, M., Arron, S. T., Beutler, B., Bononi, A., Cavenee, W., Cleaver, J. E., Croce, C. M., D’Andrea, A., Foulkes, W. D., Gaudino, G., Groden, J. L., Henske, E. P., Hickson, I. D., Hwang, P. M., Kolodner, R. D., Mak, T. W., Malkin, D., Monnat, R. J., Novelli, F., Pass, H. I. & 3 others, , 2020, In: Nature Reviews Cancer. 20, p. 533–549Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Two integrated and highly predictive functional analysis-based procedures for the classification of MSH6 variants in Lynch syndrome
Drost, M., Tiersma, Y., Glubb, D., Kathe, S., van Hees, S., Calléja, F., Zonneveld, J. B. M., Boucher, K. M., Ramlal, R. P. E., Thompson, B. A., Rasmussen, Lene Juel, Greenblatt, M. S., Lee, A., Spurdle, A. B., Tavtigian, S. V. & de Wind, N., 2020, In: Genetics in Medicine. 22, p. 847–856Research output: Contribution to journal › Journal article › Research › peer-review
- 2019
- Published
The influence of fibrillin‐1 and physical activity upon tendon tissue morphology and mechanical properties in mice
Tran, P. H. T., Skrba, T., Wondimu, E., Galatioto, G., Svensson, R. B., Olesen, A. T., Mackey, Abigail, Magnusson, Stig Peter, Ramirez, F. & Kjær, Michael, 1 Nov 2019, In: Physiological Reports. 7, 21, 9 p., e14267 .Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Influence of Oral Contraceptive Use on Adaptations to Resistance Training
Dalgaard, L. B., Dalgas, U., Andersen, J. L., Rossen, N. B., Moller, A. B., Stodkilde-Jorgensen, H., Jorgensen, J. O., Kovanen, V., Couppe, C., Langberg, Henning, Kjær, Michael & Hansen, M., Jul 2019, In: Frontiers in Physiology. 10, 14 p., 824.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effects of Long-Term Physical Activity and Diet on Skin Glycation and Achilles Tendon Structure
Hjerrild, J. N., Wobbe, A., Stausholm, M. B., Larsen, A. E., Josefsen, C. O., Malmgaard-Clausen, N. M., Dela, Flemming, Kjær, Michael, Magnusson, Stig Peter, Hansen, M., Svensson, R. B. & Couppé, C., 22 Jun 2019, In: Nutrients. 11, 6Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Immobilization Decreases FOXO3a Phosphorylation and Increases Autophagy-Related Gene and Protein Expression in Human Skeletal Muscle
Møller, A. B., Vendelbo, M. H., Schjerling, Peter, Couppé, Christian, Møller, N., Kjær, Michael, Hansen, M. & Jessen, N., 14 Jun 2019, In: Frontiers in Physiology. 10, 14 p., 736.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Age and prior exercise in vivo determine the subsequent in vitro molecular profile of myoblasts and non-myogenic cells derived from human skeletal muscle
Bechshøft, C. J. L., Jensen, S. M., Schjerling, P., Andersen, J. L., Svensson, R. B., Eriksen, C. S., Mkumbuzi, N. S., Kjær, Michael & Mackey, Abigail, Jun 2019, In: American Journal of Physiology: Cell Physiology. 316, 6, p. C898-C912Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Lactate-Mediated Protection of Retinal Ganglion Cells
Vohra, Rupali, Aldana, Blanca, Bulli, G., Jensen, Dorte Skytt, Waagepetersen, Helle S., Bergersen, L. H. & Kolko, Miriam, 19 Apr 2019, In: Journal of Molecular Biology. 431, 9, p. 1878-1888 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Lack of muscle fibre hypertrophy, myonuclear addition, and satellite cell pool expansion with resistance training in 83-94-year-old men and women
Karlsen, Anders, Bechshøft, R. L., Malmgaard-Clausen, N. M., Andersen, J. L., Schjerling, P., Kjær, Michael & Mackey, Abigail, 3 Mar 2019, In: Acta Physiologica. 227, ja, e13271.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Dual Properties of Lactate in Müller Cells: The Effect of GPR81 Activation
Vohra, Rupali, Aldana, Blanca, Waagepetersen, Helle S., Bergersen, L. H. & Kolko, Miriam, 1 Mar 2019, In: Investigative Ophthalmology & Visual Science. 60, 4, p. 999-1008 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Behandling af akutte muskelskader
Bayer, M. L., Mackey, Abigail, Magnusson, Stig Peter, Krogsgaard, Michael R. & Kjær, Michael, 18 Feb 2019, In: Ugeskrift for Laeger. 181, 8, 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Potential metabolic markers in glaucoma and their regulation in response to hypoxia
Vohra, Rupali, Dalgaard, L. M., Vibaek, J., Langbøl, Mia Aggergaard, Bergersen, L. H., Olsen, N. V., Hassel, B., Chaudhry, F. A. & Kolko, Miriam, 28 Jan 2019, In: Acta Ophthalmologica. 97, 6, p. 567-576Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A Ketogenic Diet Improves Mitochondrial Biogenesis and Bioenergetics via the PGC1α-SIRT3-UCP2 Axis
Hasan-Olive, M. M., Lauritzen, K. H., Ali, M., Rasmussen, Lene Juel, Storm-Mathisen, J. & Bergersen, L. H., 2019, In: Neurochemical Research. 44, 1, p. 22-37 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A defined human aging phenome
Andreassen, Søren Norge, Ben Ezra, Michael & Scheibye-Knudsen, Morten, 2019, In: Aging. 11, 15, p. 5786-5806 21 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A functional assay–based procedure to classify mismatch repair gene variants in Lynch syndrome
Drost, M., Tiersma, Y., Thompson, B. A., Frederiksen, J. H., Keijzers, G., Glubb, D., Kathe, S., Osinga, J., Westers, H., Pappas, L., Boucher, K. M., Molenkamp, S., Zonneveld, J. B., van Asperen, C. J., Goldgar, D. E., Wallace, S. S., Sijmons, R. H., Spurdle, A. B., Rasmussen, L. J., Greenblatt, M. S. & 2 others, , 2019, In: Genetics in Medicine. 21, p. 1486–1496Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Altered alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor function and expression in hippocampus in a rat model of attention-deficit/hyperactivity disorder (ADHD)
Medin, T., Jensen, V., Skare, O., Storm-Mathisen, J., Hvalby, O. & Bergersen, L. H., 2019, In: Behavioural Brain Research. 360, p. 209-215 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
An anti-inflammatory phenotype in visceral adipose tissue of old lean mice, augmented by exercise
Ziegler, A. K., Damgaard, A., Mackey, Abigail, Schjerling, Peter, Magnusson, Stig Peter, Olesen, A. T., Kjær, Michael & Schéele, Camilla Charlotte Nielsen, 2019, In: Scientific Reports. 9, 11 p., 12069.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Artificial intelligence for aging and longevity research: Recent advances and perspectives
Zhavoronkov, A., Mamoshina, P., Vanhaelen, Q., Scheibye-Knudsen, Morten, Moskalev, A. & Aliper, A., 2019, In: Ageing Research Reviews. 49, p. 49-66 18 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Blood Biochemistry Analysis to Detect Smoking Status and Quantify Accelerated Aging in Smokers
Mamoshina, P., Kochetov, K., Cortese, F., Kovalchuk, A., Aliper, A., Putin, E., Scheibye-Knudsen, Morten, Cantor, C. R., Skjodt, N. M., Kovalchuk, O. & Zhavoronkov, A., 2019, In: Scientific Reports. 9, 10 p., 142.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Brain Responses to Passive Sensory Stimulation Correlate With Intelligence
Horwitz, A., Klemp, Marc Patrick Brag, Horwitz, Henrik, Thomsen, M. D., Rostrup, Egill, Mortensen, Erik Lykke, Osler, Merete, Lauritzen, Martin & Benedek, K., 2019, In: Frontiers in Aging Neuroscience. 11, 17 p., 201.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Chromosome instability syndromes
Taylor, A. M. R., Rothblum-Oviatt, C., Ellis, N. A., Hickson, Ian David, Meyer, S., Crawford, T. O., Smogorzewska, A., Pietrucha, B., Weemaes, C. & Stewart, G. S., 2019, In: Nature Reviews. Disease Primers. 5, 20 p., 64.Research output: Contribution to journal › Review › Research › peer-review
- Published
Copenhagen Consensus statement 2019: Physical activity and ageing
Bangsbo, J., Blackwell, J., Boraxbekk, C-J., Caserotti, P., Dela, F., Evans, A. B., Jespersen, A. P., Gliemann, L., Kramer, A. F., Lundbye-Jensen, J., Mortensen, E. L., Lassen, A. J., Gow, A. J., Harridge, S. D. R., Hellsten, Y., Kjær, M., Kujala, U. M., Rhodes, R. E., Pike, E. C. J., Skinner, T. & 6 others, , 2019, In: British Journal of Sports Medicine. 53, 14, p. 856-858 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Corticosteroid injection is the best treatment in plantar fasciitis if combined with controlled training
Johannsen, F. E., Herzog, R. B., Malmgaard-Clausen, N. M., Hoegberget-Kalisz, M., Magnusson, Stig Peter & Kjær, Michael, 2019, In: Knee Surgery, Sports Traumatology, Arthroscopy. 27, 1, p. 5-12Research output: Contribution to journal › Journal article › Research › peer-review
- Published
DNA replication stress and its impact on chromosome segregation and tumorigenesis
Zhang, B. N., Bueno Venegas, A., Hickson, Ian David & Chu, W. K., 2019, In: Seminars in Cancer Biology. 55, p. 61-69Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Esc2 promotes telomere stability in response to DNA replication stress
Jørgensen, S. W., Liberti, S. E., Larsen, N. B., Lisby, Michael, Mankouri, H. W. & Hickson, Ian David, 2019, In: Nucleic Acids Research. 47, 9, p. 4597-4611 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
From powerhouse to perpetrator—mitochondria in health and disease
Fakouri, N. B., Hansen, T. L., Desler, Claus, Anugula, Sharath & Rasmussen, Lene Juel, 2019, In: Biology. 8, 2, 15 p., 35.Research output: Contribution to journal › Review › Research › peer-review
- Published
High Intensity Interval Training Ameliorates Mitochondrial Dysfunction in the Left Ventricle of Mice with Type 2 Diabetes
Baekkerud, F. H., Salerno, S., Ceriotti, P., Morland, C., Storm-Mathisen, J., Bergersen, L. H., Hoydal, M. A., Catalucci, D. & Stolen, T. O., 2019, In: Cardiovascular Toxicology. 19, 5, p. 422-431 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Human exonuclease 1 (EXO1) regulatory functions in DNA replication with putative roles in cancer
Keijzers, G., Bakula, Daniela Janina, Petr, Michael Angelo, Madsen, N. G. K., Teklu, Amanuel Abraha, Mkrtchyan, Garik, Osborne, Brenna & Scheibye-Knudsen, Morten, 2019, In: International Journal of Molecular Sciences . 20, 1, 15 p., 74.Research output: Contribution to journal › Review › Research › peer-review
- Published
Integrated method for quantitative morphometry and oxygen transport modeling in striated muscle
Al-Shammari, A. A., Kissane, R. W. P., Holbek, S., Mackey, Abigail, Andersen, T. R., Gaffney, E. A., Kjær, Michael & Egginton, S., 2019, In: Journal of Applied Physiology. 126, 3, p. 544-557 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Lamin A/C promotes DNA base excision repair
Maynard, S., Keijzers, G., Akbari, M., Ben Ezra, Michael, Hall, A., Morevati, M., Scheibye-Knudsen, Morten, Gonzalo, S., Bartek, J. & Bohr, Vilhelm, 2019, In: Nucleic Acids Research. 47, 22, p. 11709–11728Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Latest advances in aging research and drug discovery
Bakula, D., Ablasser, A., Aguzzi, A., Antebi, A., Barzilai, N., Bittner, M. I., Jensen, M. B., Calkhoven, C. F., Chen, D., de Grey, A. D. N. J., Feige, J. N., Georgievskaya, A., Gladyshev, V. N., Golato, T., Gudkov, A. V., Hoppe, T., Kaeberlein, M., Katajisto, P., Kennedy, B. K., Lal, U. & 10 others, , 2019, In: Aging. 11, 22, p. 9971-9981 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
MERTK Acts as a costimulatory receptor on human cd8 t cells
Peeters, M. J. W., Dulkeviciute, D., Draghi, A., Ritter, C., Rahbech, A., Skadborg, S. K., Seremet, T., Simoes, A. M. C., Martinenaite, E., Halldorsdottir, H. R., Andersen, Mads Hald, Olofsson, G. H., Svane, Inge Marie, Rasmussen, Lene Juel, Met, Özcan, Becker, J. C., dqp123, dqp123, Desler, Claus & Straten, P. T., 2019, In: Cancer Immunology Research. 7, 9, p. 1472-1484 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mitochondrial oxidative phosphorylation capacity of cryopreserved cells
Lauridsen, P. E., Rasmussen, Lene Juel & Desler, Claus, 2019, In: Mitochondrion. 47, p. 47-53 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Molecular indicators of denervation in ageing human skeletal muscle
Soendenbroe, C., Heisterberg, M. F., Schjerling, Peter, Karlsen, Anders, Kjær, Michael, Andersen, J. L. & Mackey, Abigail, 2019, In: Muscle & Nerve. 60, 4, p. 453-463 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Muscle-strain injury exudate favors acute tissue healing and prolonged connective tissue formation in humans
Bayer, M. L., Bang, L., Hoegberget-Kalisz, M., Svensson, R. B., Olesen, J. L., Karlsson, M. M., Schjerling, Peter, Hellsten, Ylva, Høier, B., Magnusson, Stig Peter & Kjær, Michael, 2019, In: F A S E B Journal. 33, 9, p. 10369-10382 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
PICH and TOP3A cooperate to induce positive DNA supercoiling
Bizard, A. H., Allemand, J. F., Hassenkam, Tue, Paramasivam, M., Sarlós, K., Singh, Manika Indrajit & Hickson, Ian David, 2019, In: Nature Structural and Molecular Biology. 26, 4, p. 267-274 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Sleep efficiency and neurophysiological patterns in middle-aged men are associated with cognitive change over their adult life course
Waser, M., Lauritzen, Martin, Fagerlund, Birgitte, Osler, Merete, Mortensen, Erik Lykke, Sørensen, H. B. D. & Jennum, Poul, 2019, In: Journal of Sleep Research. 28, 4, 9 p., e12793.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Spontaneous astrocytic Ca2+ activity abounds in electrically suppressed ischemic penumbra of aged mice
Fordsmann, J. C., Murmu, R. P., Cai, Changsi, Brazhe, A., Thomsen, Kirsten Joan, Zambach, S. A., wbh615, wbh615, Lind, Barbara Lykke & Lauritzen, Martin, 2019, In: Glia. 67, 1, p. 37-52 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The effect of resistance exercise upon age-related systemic and local skeletal muscle inflammation
Ziegler, A. K., Jensen, S. M., Schjerling, P., Mackey, Abigail, Andersen, J. L. & Kjær, Michael, 2019, In: Experimental Gerontology. 121, p. 19-32Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The influence of direct and indirect fibroblast cell contact on human myogenic cell behaviour and gene expression in vitro
Bechshøft, C. J. L., Schjerling, Peter, Kjær, Michael & Mackey, Abigail, 2019, In: Journal of Applied Physiology. 127, 2, p. 342-355Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Upregulation of the lactate transporter monocarboxylate transporter 1 at the blood-brain barrier in a rat model of attention-deficit/hyperactivity disorder suggests hyperactivity could be a form of self-treatment
Medin, T., Medin, H., Hefte, M. B., Storm-Mathisen, J. & Bergersen, L. H., 2019, In: Behavioural Brain Research. 360, p. 279-285 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2018
- Published
Essential Roles of Lactate in Müller Cell Survival and Function
Vohra, Rupali, Aldana, Blanca, Jensen, Dorte Skytt, Freude, Kristine, Waagepetersen, Helle S., Bergersen, L. H. & Kolko, Miriam, 1 Dec 2018, In: Molecular Neurobiology. 55, 12, p. 9108-9121 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
p38-MK2 signaling axis regulates RNA metabolism after UV-light-induced DNA damage
Borisova, M. E., Voigt, A., Tollenaere, M. A. X., Sahu, S. K., Juretschke, T., Kreim, N., Mailand, Niels, Choudhary, Chunaram, Bekker-Jensen, Simon Holst, Akutsu, M., Wagner, S. A. & Beli, P., 1 Dec 2018, In: Nature Communications. 9, p. 1-16 16 p., 1017.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Losartan has no additive effect on the response to heavy resistance exercise in human elderly skeletal muscle
Heisterberg, M. F., Andersen, J. L., Schjerling, Peter, Lund, A., Dalskov, S., Overgård Jønsson, A., Warming, N., Fogelstrøm, M., Kjær, Michael & Mackey, Abigail, Nov 2018, In: Journal of Applied Physiology. 125, 5, p. 1536-1554 19 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Carbon-14 bomb pulse dating shows that tendinopathy is preceded by years of abnormally high collagen turnover
Heinemeier, K. M., Schjerling, Peter, Øhlenschlæger, Tommy Frisgaard, Eismark, C., Olsen, J. & Kjær, Michael, Sep 2018, In: FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 32, 9, p. 4763-4775 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Anaphase: a fortune-teller of genomic instability
Bizard, A. H. & Hickson, Ian David, Jun 2018, In: Current Opinion in Cell Biology. 52, p. 112-119 8 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Effect of Losartan on the Acute Response of Human Elderly Skeletal Muscle to Exercise
Heisterberg, M. F., Andersen, J. L., Schjerling, P., Bülow, J., Lauersen, J. B., Roeber, H. L., Kjær, Michael & Mackey, Abigail, 1 Feb 2018, In: Medicine and Science in Sports and Exercise. 50, 2, p. 225–235Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Monogenic Diseases of DNA Repair
Keijzers, G., Bakula, Daniela Janina & Scheibye-Knudsen, Morten, 1 Feb 2018, In: The New England Journal of Medicine. 378, 5, p. 491-492 2 p.Research output: Contribution to journal › Comment/debate › Research › peer-review
- Published
Exercise induced effects on muscle function and range of motion in patients with hip osteoarthritis
Bieler, T., Siersma, Volkert Dirk, Magnusson, Stig Peter, Kjær, Michael & Beyer, N., Jan 2018, In: Physiotherapy Research International. 23, 1, 9 p., e1697.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A Molecular Toolbox to Engineer Site-Specific DNA Replication Perturbation
Larsen, N. B., Hickson, Ian David & Mankouri, H. W., 2018, Genome Instability: Methods and Protocols. Springer, Vol. 1672. p. 295-309 15 p. (Methods in molecular biology (Clifton, N.J.)).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
Active role of capillary pericytes during stimulation-induced activity and spreading depolarization
Khennouf, Lila, Gesslein, B., Brazhe, A., Octeau, J. C., Kutuzov, Nikolay, Khakh, B. S. & Lauritzen, Martin, 2018, In: Brain. 141, 7, p. 2032-2046 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Aging and drug discovery
Bakula, D., Aliper, A. M., Mamoshina, P., Petr, M. A., Teklu, A., Baur, J. A., Campisi, J., Ewald, C. Y., Georgievskaya, A., Gladyshev, V. N., Kovalchuk, O., Lamming, D. W., Luijsterburg, M. S., Martín-Montalvo, A., Maudsley, S., Mkrtchyan, G. V., Moskalev, A., Jay Olshansky, S., Ozerov, I. V., Pickett, A. & 3 others, , 2018, In: Aging. 10, 11, p. 3079-3088 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Alternative translation initiation generates a functionally distinct isoform of the stress-activated kinase MK2
Trulley, P., Snieckute, Goda, Bekker-Jensen, D. B., Menon, M. B., Freund, R., Kotlyarov, A., Olsen, Jesper Velgaard, Diaz-Muñoz, M. D., Turner, M., Bekker-Jensen, Simon Holst, Gaestel, M. & Tiedje, C., 2018, bioRxiv, 46 p. (bioRxiv).Research output: Working paper › Preprint › Research
- Published
CaMKII-dependent endoplasmic reticulum fission by whisker stimulation and during cortical spreading depolarization
Kucharz, Krzysztof & Lauritzen, Martin, 2018, In: Brain. 141, 4, p. 1049-1062 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cellular homeostatic tension and force transmission measured in human engineered tendon
Giannopoulos, A., Svensson, R. B., Heinemeier, K. M., Schjerling, P., Kadler, K. E., Holmes, D. F., Kjær, Michael & Magnusson, Stig Peter, 2018, In: Journal of Biomechanics. 78, p. 161-165 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Contributions of the glycocalyx, endothelium, and extravascular compartment to the blood-brain barrier
Kutuzov, Nikolay, Flyvbjerg, H. & Lauritzen, Martin, 2018, In: Proceedings of the National Academy of Sciences of the United States of America. 115, 40, p. E9429-E9438 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Detection of Ultrafine Anaphase Bridges
Bizard, A. H., Nielsen, Christian Friberg & Hickson, Ian David, 2018, Genome Instability: Methods and Protocols. Springer, Vol. 1672. p. 495-508 14 p. (Methods in molecular biology (Clifton, N.J.)).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
EEG correlates of visual short-term memory in older age vary with adult lifespan cognitive development
Wiegand, I., Lauritzen, Martin, Osler, Merete, Mortensen, Erik Lykke, Rostrup, E., Rask, L., Richard, N., Horwitz, A., Benedek, K., Vangkilde, Signe & Petersen, Anders, 2018, In: Neurobiology of Aging. 62, p. 210-220 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Enhancement of Astroglial Aerobic Glycolysis by Extracellular Lactate-Mediated Increase in cAMP
Vardjan, N., Chowdhury, H. H., Horvat, A., Velebit, J., Malnar, M., Muhič, M., Kreft, M., Krivec, Š. G., Bobnar, S. T., Miš, K., Pirkmajer, S., Offermanns, S., Henriksen, G., Storm-mathisen, J., Bergersen, L. H. & Zorec, R., 2018, In: Frontiers in Molecular Neuroscience. 11, 15 p., 148.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Fast Ca2+ responses in astrocyte end-feet and neurovascular coupling in mice
Lind, Barbara Lykke, Jessen, S. B., Lønstrup, M., Joséphine, C., Bonvento, G. & Lauritzen, Martin, 2018, In: Glia. 66, 2, p. 348-358 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Human cancer cells utilize mitotic DNA synthesis to resist replication stress at telomeres regardless of their telomere maintenance mechanism
Özer, Ö., Bhowmick, Rahul, Liu, Ying & Hickson, Ian David, 2018, In: OncoTarget. 9, 22, p. 15836-15846 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Hyposalivation and Poor Dental Health Status Are Potential Correlates of Age-Related Cognitive Decline in Late Midlife in Danish Men
Sørensen, Christiane Elisabeth, Hansen, N. L., Mortensen, Erik Lykke, Lauritzen, Martin, Osler, Merete & Pedersen, Anne Marie Lynge, 2018, In: Frontiers in Aging Neuroscience. 10, p. 1-7 7 p., 10.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Ibuprofen alters human testicular physiology to produce a state of compensated hypogonadism
Kristensen, D. M., Desdoits-Lethimonier, C., Mackey, Abigail, Dalgaard, M. D., De Masi, F., Munkbøl, C. H., Styrishave, Bjarne, Antignac, J., Le Bizec, B., Platel, C., Hay-Schmidt, Anders, Jensen, T. K., Lesné, L., Mazaud-Guittot, S., Kristiansen, Karsten, Brunak, Søren, Kjær, Michael, Juul, Anders & Jégou, B., 2018, In: Proceedings of the National Academy of Sciences of the United States of America. 115, 4, p. e715-e724 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
In acutely admitted geriatric patients, offering increased physical activity during hospitalization decreases length of stay and can improve mobility
Oestergaard, A. S., Mathiesen, M. H., Karlsen, Anders, Turtumoeygaard, I. F., Vahlgren, J., Kjær, Michael & Beyer, N., 2018, In: Translational Sports Medicine. 1, 1, p. 46-53Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Inducing and Detecting Mitotic DNA Synthesis at Difficult-to-Replicate Loci
Garribba, L., Wu, Wei, Özer, Ö., Bhowmick, Rahul, Hickson, Ian David & Liu, Ying, 2018, Methods in Enzymology: Mechanisms of DNA Recombination and Genome Rearrangements: Intersection between Homologous Recombination, DNA Replication and DNA Repair. Spies, M. & Malkova, A. (eds.). Elsevier, Vol. 601. p. 45-58 14 p. (Methods in Enzymology; No. 601).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
Initial brain aging: heterogeneity of mitochondrial size is associated with decline in complex I-linked respiration in cortex and hippocampus
Thomsen, Kirsten Joan, Yokota, T., Hasan-Olive, M. M., Sherazi, N., Fakouri, N. B., Desler, Claus, Regnell, C. E., Larsen, S., Rasmussen, Lene Juel, Dela, Flemming, Bergersen, L. H. & Lauritzen, Martin, 2018, In: Neurobiology of Aging. 61, p. 215-224 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Loss of PICH Results in Chromosomal Instability, p53 Activation, and Embryonic Lethality
Albers, E., Sbroggiò, M., Pladevall Morera, David, Bizard, A. H., Avram, Alexandra Ioana, Gonzalez, P., Martin Gonzalez, Javier, Hickson, Ian David & Lopez-Contreras, Andres, 2018, In: Cell Reports. 24, 12, p. 3274-3284 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Lower tendon stiffness in very old compared with old individuals is unaffected by short-term resistance training of skeletal muscle
Eriksen, C. S., Henkel, C., Svensson, R. B., Agergaard, A., Couppé, C., Kjær, Michael & Magnusson, Stig Peter, 2018, In: Journal of Applied Physiology. 125, 1, p. 205-214 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Monitoring of blood oxygenation in brain by resonance Raman spectroscopy
Brazhe, N. A., Thomsen, Kirsten Joan, wbh615, wbh615, Brazhe, A. R., Nikelshparg, E. I., Maksimov, G. V., Lauritzen, Martin & Sosnovtseva, Olga, 2018, In: Journal of Biophotonics. 11, 6, 10 p., e201700311.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mutations in TOP3A Cause a Bloom Syndrome-like Disorder
GOSgene, G., 2018, In: American Journal of Human Genetics. 103, 2, p. 221-231 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Pathways for maintenance of telomeres and common fragile sites during DNA replication stress
Özer, Ö. & Hickson, Ian David, 2018, In: Open Biology. 8, 4, 11 p., 180018.Research output: Contribution to journal › Review › Research › peer-review
- Published
Plasticity in central neural drive with short-term disuse and recovery - effects on muscle strength and influence of aging
Hvid, L. G., Aagaard, P., Ørtenblad, N., Kjær, Michael & Suetta, Charlotte, 2018, In: Experimental Gerontology. 106, p. 145-153 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Population specific biomarkers of human aging: A big data study using South Korean, Canadian, and Eastern European patient populations
Mamoshina, P., Kochetov, K., Putin, E., Cortese, F., Aliper, A., Lee, W. S., Ahn, S. M., Uhn, L., Skjodt, N., Kovalchuk, O., Scheibye-Knudsen, Morten & Zhavoronkov, A., 2018, In: Journals of Gerontology - Series A Biological Sciences and Medical Sciences. 73, 11, p. 1482-1490 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Reconstitution of anaphase DNA bridge recognition and disjunction
Sarlós, K., Biebricher, A. S., Bizard, A. H., Bakx, J. A. M., Ferreté-Bonastre, A. G., Modesti, M., Paramasivam, M., Yao, Q., Peterman, E. J. G., Wuite, G. J. L. & Hickson, Ian David, 2018, In: Nature Structural and Molecular Biology. 25, 9, p. 868-876 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Response to resistance training following immobilization: Influence of delaying post-exercise meal
Larsen, M. S., Couppé, C., Møller, A. B., Schjerling, P., Andersen, J. L., Nygaard, R. H., Langberg, Henning, Kjær, Michael & Hansen, M., 2018, In: Translational Sports Medicine. 1, 5, p. 191-203Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Role of tissue perfusion, muscle strength recovery, and pain in rehabilitation after acute muscle strain injury: A randomized controlled trial comparing early and delayed rehabilitation
Bayer, M. L., Høgberget-Kalisz, M., Jensen, M. H., Olesen, J. L., Svensson, R. B., Couppé, C., Boesen, Mikael Ploug, Nybing, J. D., Kurt, E. Y., Magnusson, Stig Peter & Kjær, Michael, 2018, In: Scandinavian Journal of Medicine and Science in Sports. 28, 12, p. 2579-2591 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Spinal dorsal horn astrocytes release GABA in response to synaptic activation
Christensen, R. K., Delgado-Lezama, R., Russo, R. E., Lind, Barbara Lykke, Alcocer, E. L., Rath, Martin Fredensborg, Fabbiani, G., Schmitt, Nicole, Lauritzen, Martin, Petersen, A. V., Carlsen, Eva Maria Meier & Perrier, Jean-Francois Marie, 2018, In: The Journal of Physiology. 596, 20, p. 4983-4994 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Stimulation-induced increases in cerebral blood flow and local capillary vasoconstriction depend on conducted vascular responses
Cai, Changsi, Fordsmann, J. C., Jensen, S. H., Gesslein, B., wbh615, wbh615, Hald, B. O., Zambach, S. A., Larsen, Birger Brodin & Lauritzen, Martin, 2018, In: Proceedings of the National Academy of Sciences of the United States of America. 115, 25, p. E5796-E5804 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Detection and Analysis of Chromosome Fragile Sites
Bjerregaard, Victoria Alexandra, Özer, Ö., Hickson, Ian David & Liu, Ying, 2018, Genome Instability: Methods and Protocols. Springer, Vol. 1672. p. 471-482 12 p. (Methods in molecular biology (Clifton, N.J.)).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
The Ruptured Achilles Tendon Elongates for 6 Months After Surgical Repair Regardless of Early or Late Weightbearing in Combination With Ankle Mobilization: A Randomized Clinical Trial
Eliasson, P., Agergaard, A., Couppe, C., Svensson, R., Hoeffner, R., Warming, S., Warming, N., Holm, C., Jensen, M. H., Krogsgaard, Michael R., Kjær, Michael & Magnusson, Stig Peter, 2018, In: American Journal of Sports Medicine. 46, 10, p. 2492-2502Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The inhibitors of soluble adenylate cyclase 2-OHE, KH7, and bithionol compromise mitochondrial ATP production by distinct mechanisms
Jakobsen, Emil, Lange, S. C., Andersen, Jens Velde, Desler, Claus, Kihl, H. F., Hohnholt, M., Stridh, M. H., Rasmussen, Lene Juel, Waagepetersen, Helle S. & Bak, Lasse Kristoffer, 2018, In: Biochemical Pharmacology. 155, p. 92-101 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The role of mitochondrial dysfunction in the progression of Alzheimer’s disease
Desler, Claus, Lillenes, M. S., Tønjum, T. & Rasmussen, Lene Juel, 2018, In: Current Medicinal Chemistry. 25, 40, p. 5578 - 5587Research output: Contribution to journal › Review › Research › peer-review
- Published
Vive la radiorésistance! Converging research in radiobiology and biogerontology to enhance human radioresistance for deep space exploration and colonization
Cortese, F., Klokov, D., Osipov, A., Stefaniak, J., Moskalev, A., Schastnaya, J., Cantor, C., Aliper, A., Mamoshina, P., Ushakov, I., Sapetsky, A., Vanhaelen, Q., Alchinova, I., Karganov, M., Kovalchuk, O., Wilkins, R., Shtemberg, A., Moreels, M., Baatout, S., Izumchenko, E. & 10 others, , 2018, In: OncoTarget. 9, 18, p. 14692-14722 31 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Life-long endurance exercise in humans: circulating levels of inflammatory markers and leg muscle size
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