Damage and Repair

  1. Published

    RNF111/Arkadia is a SUMO-targeted ubiquitin ligase that facilitates the DNA damage response

    Poulsen, S. L., Hansen, R. K., Wagner, S. A., van Cuijk, L., van Belle, G. J., Streicher, W., Wikström, M., Choudhary, Chunaram, Houtsmuller, A. B., Marteijn, J. A., Bekker-Jensen, Simon Holst & Mailand, Niels, 10 Jun 2013, In: Journal of Cell Biology. 201, 6, p. 797-807 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    RNA-sequencing and immunofluorescence of the myotendinous junction of mature horses and humans

    Jakobsen, J. R., Schjerling, Peter, Svensson, R. B., Buhl, Rikke, Carstensen, Helena, Koch, M., Rindom Krogsgaard, M. R., Kjær, Michael & Mackey, Abigail, 2021, In: American journal of physiology. Cell physiology. 321, p. C453–C470

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    RECQL4 Promotes DNA End Resection in Repair of DNA Double-Strand Breaks

    Lu, H., Shamanna, R. A., Keijzers, G., Anand, R., Rasmussen, Lene Juel, Cejka, P., Croteau, D. L. & Bohr, Vilhelm, 28 Jun 2016, In: Cell Reports. 16, 1, p. 161-173 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    RECQ5 Helicase Cooperates with MUS81 Endonuclease in Processing Stalled Replication Forks at Common Fragile Sites during Mitosis

    Di Marco, S., Hasanova, Z., Kanagaraj, R., Chappidi, N., Altmannova, V., Menon, S., Sedlackova, H., Langhoff, J., Surendranath, K., Hühn, D., Bhowmick, Rahul, Marini, V., Ferrari, S., Hickson, Ian David, Krejci, L. & Janscak, P., 1 Jun 2017, In: Molecular Cell. 66, 5, p. 658-671.e8

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    RANKL regulates testicular cancer growth and Denosumab treatment has suppressive effects on GCNIS and advanced seminoma

    Andreassen, C. H., Lorenzen, M., Nielsen, J. E., Kafai Yahyavi, S., Toft, Birgitte Grønkær, Ingerslev, L. R., Clemmensen, Christoffer, Rasmussen, Lene Juel, Bokemeyer, C., Juul, Anders, Jørgensen, A. & Jensen, M. B., 2022, In: British Journal of Cancer. 127, p. 408-421

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    RAD52 Facilitates Mitotic DNA Synthesis Following Replication Stress

    Bhowmick, Rahul, Minocherhomji, S. & Hickson, Ian David, 15 Dec 2016, In: Molecular Cell. 64, 6, p. 1117-1126 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    RAD51 protects human cells from transcription-replication conflicts

    Bhowmick, Rahul, Lerdrup, Mads, Gadi, Sampath Amitash, Rossetti, G. G., Singh, Manika Indrajit, Liu, Ying, Halazonetis, T. D. & Hickson, Ian David, 2022, In: Molecular Cell. 82, 18, p. 3366-3381.e9

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Quantification of cell density in rat Achilles tendon: development and application of a new method

    Couppé, C., Svensson, R. B., Heinemeier, K. M., Thomsen, E. W., Bayer, M. L., Christensen, L., Kjær, Michael, Magnusson, Stig Peter & Schjerling, P., Jan 2017, In: Histochemistry and Cell Biology. 147, 1, p. 97-102 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Purinergic Signaling in Pericytes of the Blood-Brain Barrier

    Jensen, S. H., Helms, H. C. C., Jessen, S. B., Lauritzen, Martin, Waagepetersen, Helle S. & Larsen, Birger Brodin, Jul 2015.

    Research output: Contribution to conferencePosterResearchpeer-review

  10. Published

    Protocol for the combined cardiometabolic deep phenotyping and registry-based 20-year follow-up study of the Inter99 cohort

    Bjørnsbo, K. S., Brøns, C., Aadahl, M., Kampmann, F. B., Friis Bryde Nielsen, C., Lundbergh, B., Christensen, R. W., Kårhus, L. L., Madsen, A. L., Hansen, C. S., Nørgaard, K., Jørgensen, N. R., Suetta, C., Kjaer, M., Grarup, N., Kanters, J., Larsen, M., Køber, L., Kofoed, K. F., Loos, R. & 3 others, Hansen, Torben, Linneberg, Allan René & Vaag, Allan, 2024, In: BMJ Open. 14, 1, 10 p., e078501.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Proteomics identifies differences in fibrotic potential of extracellular vesicles from human tendon and muscle fibroblasts

    Yeung, C. C., Schoof, E. M., Tamáš, M., Mackey, Abigail & Kjær, Michael, 2020, In: Cell Communication and Signaling. 18, 1, 15 p., 177.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Proteomics Reveals Global Regulation of Protein SUMOylation by ATM and ATR Kinases during Replication Stress

    Munk, S., Sigurðsson, J. O., Xiao, Z., Batth, Tanveer Singh, Franciosa, Giulia, von Stechow, L., Lopez-Contreras, Andres, Vertegaal, A. C. O. & Olsen, Jesper Velgaard, 2017, In: Cell Reports. 21, 2, p. 546-558 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Proteome-wide analysis of SUMO2 targets in response to pathological DNA replication stress in human cells

    Bursomanno, S., Beli, P., Khan, A. M., Minocherhomji, S., Wagner, S. A., Bekker-Jensen, Simon Holst, Mailand, Niels, Choudhary, Chunaram, Hickson, Ian David & Liu, Ying, Jan 2015, In: DNA Repair. 25, p. 84-96 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Protecting the Aging Genome

    Petr, Michael Angelo, Tulika, T., Carmona Marin, Lina Maria & Scheibye-Knudsen, Morten, 2020, In: Trends in Cell Biology. 30, 2, p. 117-132 16 p.

    Research output: Contribution to journalReviewResearchpeer-review

  15. Published

    Prospective multi-centre randomised trial comparing induction of labour with a double-balloon catheter versus dinoprostone

    Løkkegaard, Ellen Christine Leth, Lundstrøm, M., Kjær, Michael, Christensen, I. J., Pedersen, H. B. & Nyholm, H., 2015, In: Journal of Obstetrics and Gynaecology. 35, 8, p. 797-802 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Prognostic value of periodic electroencephalographic discharges for neurological patients with profound disturbances of consciousness

    Pedersen, G. L., Rasmussen, S., Gyllenborg, J., Benedek, Krisztina & Lauritzen, Martin, 2013, In: Clinical Neurophysiology. 124, 1, p. 44-51 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Processing of homologous recombination repair intermediates by the Sgs1-Top3-Rmi1 and Mus81-Mms4 complexes

    Hickson, Ian David & Mankouri, H. W., Oct 2011, In: Cell Cycle. 10, 18, p. 3078-85 8 p.

    Research output: Contribution to journalReviewResearchpeer-review

  18. Published

    Principal cell spiking, postsynaptic excitation, and oxygen consumption in the rat cerebellar cortex

    Thomsen, Kirsten Joan, Piilgaard, H., Gjedde, Albert, Bonvento, G., Lauritzen, Martin, Thomsen, K., Hansen, H. P., Gjedde, A., Bonvento, G. & Lauritzen, Martin, 1 Sep 2009, In: Journal of Neurophysiology. 102, 3, p. 1503-12 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Prevention of Cell Death by Activation of Hydroxycarboxylic Acid Receptor 1 (GPR81) in Retinal Explants

    Vohra, Rupali, Sanz-Morello, B., Tams, A. L. M., Mouhammad, Zaynab Ahmad, Freude, Kristine, Hannibal, Jens, Aldana, Blanca, Bergersen, L. H. & Kolko, Miriam, 2022, In: Cells. 11, 13, 2098.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Preventing tendon overuse injuries

    Cook, J., Kongsgaard, M., Kjær, Michael, Bahr, R. & Engebretsen, L., 2009, Sports Injury Prevention. Wiley-Blackwell, p. 187-196 9 p.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearch

  21. Published

    Preserved stem cell content and innervation profile of elderly human skeletal muscle with lifelong recreational exercise

    Soendenbroe, C., Dahl, C. L., Meulengracht, C., Tamáš, M., Svensson, R. B., Schjerling, Peter, Kjær, Michael, Andersen, J. L. & Mackey, Abigail, 2022, In: The Journal of Physiology. 600, 8, p. 1969-1989

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Preserved skeletal muscle protein anabolic response to acute exercise and protein intake in well-treated rheumatoid arthritis patients

    Mikkelsen, U. R., Dideriksen, K., Andersen, M. B., Boesen, A., Malmgaard-Clausen, N. M., Sørensen, I. J., Schjerling, Peter, Kjær, Michael & Holm, L., 2015, In: Arthritis Research & Therapy (Print). 17, p. 271

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Preserved capacity for satellite cell proliferation, regeneration, and hypertrophy in the skeletal muscle of healthy elderly men

    Karlsen, Anders, Soendenbroe, C., Malmgaard‐clausen, N. M., Wagener, F., Moeller, C. E., Senhaji, Z., Damberg, K., Andersen, J. L., Schjerling, P., Kjær, Michael & Mackey, Abigail, 2020, In: The FASEB Journal. 34, 5, p. 6418-6436

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Predicting the impact of Lynch syndrome-causing missense mutations from structural calculations

    Nielsen, S. V., Stein, Amelie, Dinitzen, A. B., Papaleo, E., Tatham, M. H., Poulsen, E. G., Kassem, M. M., Rasmussen, Lene Juel, Lindorff-Larsen, Kresten & Hartmann-Petersen, Rasmus, 19 Apr 2017, In: PLoS Genetics. 13, 4, 26 p., e1006739.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Potential metabolic markers in glaucoma and their regulation in response to hypoxia

    Vohra, Rupali, Dalgaard, L. M., Vibaek, J., Langbøl, Mia Aggergaard, Bergersen, L. H., Olsen, N. V., Hassel, B., Chaudhry, F. A. & Kolko, Miriam, 28 Jan 2019, In: Acta Ophthalmologica. 97, 6, p. 567-576

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Potential biomarkers of DNA replication stress in cancer

    Ren, L., Chen, L., Wu, Wei, Garribba, L., Tian, H., Liu, Z., Vogel, Ivan, Li, C., Hickson, Ian David & Liu, Ying, 2017, In: OncoTarget. 8, 23, p. 36996-37008 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Positive muscle protein net balance and differential regulation of atrogene expression after resistance exercise and milk protein supplementation

    Reitelseder, S., Agergaard, J., Doessing, S., Helmark, I. C., Schjerling, Peter, van Hall, Gerrit, Kjær, Michael & Holm, L., 1 Feb 2014, In: European Journal of Nutrition. 53, 1, p. 321-33 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Population specific biomarkers of human aging: A big data study using South Korean, Canadian, and Eastern European patient populations

    Mamoshina, P., Kochetov, K., Putin, E., Cortese, F., Aliper, A., Lee, W. S., Ahn, S. M., Uhn, L., Skjodt, N., Kovalchuk, O., Scheibye-Knudsen, Morten & Zhavoronkov, A., 2018, In: Journals of Gerontology - Series A Biological Sciences and Medical Sciences. 73, 11, p. 1482-1490 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Pooled analysis of frontal lobe transcriptomic data identifies key mitophagy gene changes in Alzheimer's disease brain

    Mei, T., Li, Yuan, Orduña Dolado, A., Li, Zhiquan, Andersson, Robin, Berliocchi, Laura & Rasmussen, Lene Juel, 2023, In: Frontiers in Aging Neuroscience. 15, 14 p., 1101216.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Plasticity in central neural drive with short-term disuse and recovery - effects on muscle strength and influence of aging

    Hvid, L. G., Aagaard, P., Ørtenblad, N., Kjær, Michael & Suetta, Charlotte, 2018, In: Experimental Gerontology. 106, p. 145-153 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    Physical activity as intervention for age-related loss of muscle mass and function: protocol for a randomised controlled trial (the LISA study)

    Eriksen, C. S., Garde, Ellen, Reislev, N. L., Wimmelmann, Cathrine Lawaetz, Bieler, T., Ziegler, A. K., Gylling, A. T., Dideriksen, K. J., Siebner, Hartwig Roman, Mortensen, Erik Lykke & Kjær, Michael, Dec 2016, In: B M J Open. 6, 12, p. 1-13 13 p., e012951.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    Persistent increase in oxygen consumption and impaired neurovascular coupling after spreading depression in rat neocortex

    Hansen, H. P. & Lauritzen, Martin, 1 Sep 2009, In: Journal of Cerebral Blood Flow and Metabolism. 29, 9, p. 1517-27 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    Persistent Deficits after an Achilles Tendon Rupture: A Narrative Review

    Høffner, Rikke, Svensson, R. B., Bjerregaard, N., Kjær, Michael & Magnusson, Stig Peter, 2022, In: Translational Sports Medicine. 2022

    Research output: Contribution to journalReviewResearchpeer-review

  34. Published

    Pathways for maintenance of telomeres and common fragile sites during DNA replication stress

    Özer, Ö. & Hickson, Ian David, 2018, In: Open Biology. 8, 4, 11 p., 180018.

    Research output: Contribution to journalReviewResearchpeer-review

  35. Published

    Pathways for Holliday Junction Processing during Homologous Recombination in Saccharomyces cerevisiae

    Ashton, T. M., Mankouri, H. W., Heidenblut, A., McHugh, P. J. & Hickson, Ian David, 1 May 2011, In: Molecular and Cellular Biology. 31, 9, p. 1921-33 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    Pathway-specific variations in neurovascular and neurometabolic coupling in rat primary somatosensory cortex

    Enager, P., Hansen, H. P., Offenhauser, N., Kocharyan, A., Fernandes, P., Hamel, E. & Lauritzen, Martin, 1 May 2009, In: Journal of Cerebral Blood Flow and Metabolism. 29, 5, p. 976-86 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    Pathological assessment of mismatch repair gene variants in Lynch syndrome: Past, present, and future

    Rasmussen, Lene Juel, Heinen, C. D., Royer-Pokora, B., Drost, M., Tavtigian, S., Hofstra, R. M. W. & de Wind, N., Dec 2012, In: Human Mutation. 33, 12, p. 1617-25 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    Pathological Tendon Histology in Early and Chronic Human Patellar Tendinopathy

    Malmgaard-Clausen, N. M., Kjær, Michael & Dakin, S. G., 2022, In: Translational Sports Medicine. 2022, 2799665.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Passive Double-Sensory Evoked Coherence Correlates with Long-Term Memory Capacity

    Horwitz, A., Mortensen, Erik Lykke, Osler, Merete, Fagerlund, Birgitte, Lauritzen, Martin & Benedek, K., 14 Dec 2017, In: Frontiers in Human Neuroscience. 11, 21 p., 598.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    Partial inhibition of mitochondrial-linked pyrimidine synthesis increases tumorigenic potential and lysosome accumulation

    Desler, Claus, Durhuus, J. A., Hansen, T. L. L., Anugula, Sharath, Zelander, N. T., Bøggild, S. & Rasmussen, Lene Juel, 2022, In: Mitochondrion. 64, p. 73-81 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    PSD-95 uncoupling from NMDA receptors by Tat-N-dimer ameliorates neuronal depolarization in cortical spreading depression

    Kucharz, Krzysztof, Søndergaard Rasmussen, I., Bach, Anders, Strømgaard, Kristian & Lauritzen, Martin, 2017, In: Journal of Cerebral Blood Flow and Metabolism. 37, 5, p. 1820-1828

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    PICH promotes sister chromatid disjunction and co-operates with topoisomerase II in mitosis

    Nielsen, Christian Friberg, Huttner, D., Bizard, A. H., Hirano, S., Li, T., Palmai-Pallag, T., Bjerregaard, Victoria Alexandra, Liu, Ying, Nigg, E. A., Wang, L. H. & Hickson, Ian David, 2015, In: Nature Communications. 6, 15 p., 8962.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    PICH promotes mitotic chromosome segregation: Identification of a novel role in rDNA disjunction

    Nielsen, Christian Friberg & Hickson, Ian David, 17 Oct 2016, In: Cell Cycle. 15, 20, p. 2704-2711 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    PICH and TOP3A cooperate to induce positive DNA supercoiling

    Bizard, A. H., Allemand, J. F., Hassenkam, Tue, Paramasivam, M., Sarlós, K., Singh, Manika Indrajit & Hickson, Ian David, 2019, In: Nature Structural and Molecular Biology. 26, 4, p. 267-274 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    PICH acts as a force-dependent nucleosome remodeler

    Spakman, D., Clement, T. V. M., Biebricher, A. S., King, G. A., Singh, Manika Indrajit, Hickson, Ian David, Peterman, E. J. G. & Wuite, G. J. L., 2022, In: Nature Communications. 13, 7277.

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    PICH Supports Embryonic Hematopoiesis by Suppressing a cGAS-STING-Mediated Interferon Response

    Geng, X., Zhang, C., Li, M., Wang, J., Ji, F., Feng, H., Xing, M., Li, F., Zhang, L., Li, W., Chen, Z., Hickson, Ian David, Shen, H. & Ying, S., 2022, In: Advanced Science. 9, 7, 2103837.

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    PICH: A DNA Translocase Specially Adapted for Processing Anaphase Bridge DNA

    Biebricher, A., Hirano, S., Enzlin, J., Wiechens, N., Streicher, W., Huttner, D., Wang, L., Nigg, E., Owen-Hughes, T., Liu, Ying, Peterman, E., Wuite, G. & Hickson, Ian David, 12 Sep 2013, In: Molecular Cell. 51, 5, p. 691-701 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    Oxygen consumption and blood flow coupling in human motor cortex during intense finger tapping: implication for a role of lactate

    Seyedi Vafaee, M., Vang, K., Bergersen, L. H. & Gjedde, Albert, Oct 2012, In: Journal of Cerebral Blood Flow and Metabolism. 32, 10, p. 1859-68 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    Oxidative damage to DNA by diesel exhaust particle exposure in co-cultures of human lung epithelial cells and macrophages

    Jantzen, K., Roursgaard, Martin, Desler, Claus, Loft, Steffen, Rasmussen, Lene Juel & Møller, Peter, Nov 2012, In: Mutagenesis. 27, 6, p. 693-701 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    Oxidative Stress-Induced Dysfunction of Muller Cells During Starvation

    Toft-Kehler, A. K., Gurubaran, I. S., Desler, Claus, Rasmussen, Lene Juel, Jensen, Dorte Skytt & Kolko, Miriam, May 2016, In: Investigative Ophthalmology & Visual Science. 57, 6, p. 2721-2728

    Research output: Contribution to journalJournal articleResearchpeer-review

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