Damage and Repair

  1. Published

    Characterization of the NTPR and BD1 interacting domains of the human PICH-BEND3 complex

    Pitchai, G. P., Hickson, Ian David, Streicher, W., Montoya, Guillermo & Mesa, Pablo, Aug 2016, In: Acta Crystallographica. Section F: Structural Biology and Crystallization Communications Online. 72, 8, p. 646-651 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    Chromosome instability syndromes

    Taylor, A. M. R., Rothblum-Oviatt, C., Ellis, N. A., Hickson, Ian David, Meyer, S., Crawford, T. O., Smogorzewska, A., Pietrucha, B., Weemaes, C. & Stewart, G. S., 2019, In: Nature Reviews. Disease Primers. 5, 20 p., 64.

    Research output: Contribution to journalReviewResearchpeer-review

  3. Published

    Chronic Sequelae After Muscle Strain Injuries: Influence of Heavy Resistance Training on Functional and Structural Characteristics in a Randomized Controlled Trial

    Bayer, M. L., Hoegberget-Kalisz, M., Svensson, R. B., Hjortshoej, M. H., Olesen, J. L., Nybing, J. D., Boesen, Mikael Ploug, Magnusson, Stig Peter & Kjær, Michael, 2021, In: American Journal of Sports Medicine. 49, 10, p. 2783-2794 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Chronic alterations in growth hormone/insulin-like growth factor-I signaling lead to changes in mouse tendon structure

    Nielsen, R. H., Clausen, N. M., Schjerling, Peter, Larsen, J. O., Martinussen, Torben, List, E. O., Kopchick, J. J., Kjær, Michael & Heinemeier, K. M., Feb 2014, In: Matrix Biology. 34, p. 96-104 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Circadian regulation of protein cargo in extracellular vesicles

    Yeung, Ching-Yan Chloé, Dondelinger, F., Schoof, E. M., Georg, B., Lu, Y., Zheng, Z., Zhang, J., Hannibal, Jens, Fahrenkrug, J. & Kjær, Michael, 2022, In: Science Advances. 8, 14, 13 p., eabc9061.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Clinical relevance of cortical spreading depression in neurological disorders: migraine, malignant stroke, subarachnoid and intracranial hemorrhage, and traumatic brain injury

    Lauritzen, Martin, Dreier, J. P., Fabricius, M., Hartings, J. A., Graf, R. & Strong, A. J., 1 Jan 2011, In: Journal of Cerebral Blood Flow and Metabolism. 31, 1, p. 17-35 19 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Cockayne syndrome: Clinical features, model systems and pathways

    Karikkineth, A. C., Scheibye-Knudsen, Morten, Fivenson, E., Croteau, D. L. & Bohr, Vilhelm, 2017, In: Ageing Research Reviews. 33, p. 3-17

    Research output: Contribution to journalReviewResearchpeer-review

  8. Published

    Cockayne syndrome group A and B proteins converge on transcription-linked resolution of non-B DNA

    Scheibye-Knudsen, M., Tseng, A., Jensen, M. B., Scheibye-Alsing, K., Fang, E. F., Iyama, T., Bharti, S. K., Marosi, K., Froetscher, L., Kassahun, H., Eckley, D. M., Maul, R. W., Bastian, P., De, S., Ghosh, S., Nilsen, H., Goldberg, I. G., Mattson, M. P., Wilson, D. M. . III., Brosh, R. M. . J. & 2 others, Gorospe, M. & Bohr, Vilhelm, 1 Nov 2016, In: National Academy of Sciences. Proceedings. 113, 44, p. 12502-12507

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Cognitive Change during the Life Course and Leukocyte Telomere Length in Late Middle-Aged Men

    Rask, L., Bendix, L., Harbo, M., Fagerlund, Birgitte, Mortensen, Erik Lykke, Lauritzen, Martin & Osler, Merete, 9 Dec 2016, In: Frontiers in Aging Neuroscience. 8, 7 p., 300.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Collagen Homeostasis and Metabolism

    Magnusson, Stig Peter, Heinemeier, K. M. & Kjær, Michael, 2016, Metabolic Influences on Risk for Tendon Disorders. Springer, Vol. 920 . p. 11-25 15 p. (Advances in Experimental Medicine and Biology, Vol. 920).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  11. Published

    Collagens in primary frozen shoulder: expression of collagen mRNA isoforms in the different phases of the disease

    Marker, L., Schjerling, P., Mackey, Abigail, Hansen, T., Jakobsen, J., Kjær, Michael & Krogsgaard, Michael R., 2021, In: Rheumatology. 60, 8, p. 3879-3887

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Colorectal cancer incidences in Lynch syndrome: a comparison of results from the prospective lynch syndrome database and the international mismatch repair consortium

    The European Hereditary Tumour Group (EHTG) and the International Mismatch Repair Consortium (IMRC), T. E. H. T. G. (. A. T. I. M. R. C. (., 2022, In: Hereditary Cancer in Clinical Practice. 20, 36.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Comparison of Tenocyte Populations from the Core and Periphery of Equine Tendons

    Zhang, C., Svensson, R. B., Montagna, C., Carstensen, Helena, Buhl, Rikke, Schoof, E. M., Kjær, Michael, Magnusson, Stig Peter & Yeung, C. Y. C., 2020, In: Journal of Proteome Research. 19, 10, p. 4137-4144 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Composition and adaptation of human myotendinous junction and neighboring muscle fibers to heavy resistance training

    Jakobsen, J. R., Mackey, Abigail, Knudsen, A. B., Kjær, Michael & Krogsgaard, Michael R., Dec 2017, In: Scandinavian Journal of Medicine & Science in Sports. 27, 12, p. 1547–1559

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Connective tissue regeneration in skeletal muscle after eccentric contraction-induced injury

    Mackey, Abigail & Kjær, Michael, Mar 2017, In: Journal of Applied Physiology. 122, 3, p. 533-540 8 p.

    Research output: Contribution to journalReviewResearchpeer-review

  16. Published

    Contributions of the glycocalyx, endothelium, and extravascular compartment to the blood-brain barrier

    Kutuzov, Nikolay, Flyvbjerg, H. & Lauritzen, Martin, 2018, In: Proceedings of the National Academy of Sciences of the United States of America. 115, 40, p. E9429-E9438 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Coordinated increase in skeletal muscle fiber area and expression of IGF-I with resistance exercise in elderly post-operative patients

    Suetta, Charlotte, Clemmensen, C., Andersen, J. L., Magnusson, Stig Peter, Schjerling, P., Kjær, Michael, Suetta, C. A., Clemmensen, C., Andersen, J. L., Magnusson, Stig Peter, Schjerling, P. & Kjær, Michael, 1 Apr 2010, In: Growth Hormone & IGF Research. 20, 2, p. 134-40 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Copenhagen Consensus statement 2019: Physical activity and ageing

    Bangsbo, J., Blackwell, J., Boraxbekk, C-J., Caserotti, P., Dela, F., Evans, A. B., Jespersen, A. P., Gliemann, L., Kramer, A. F., Lundbye-Jensen, J., Mortensen, E. L., Lassen, A. J., Gow, A. J., Harridge, S. D. R., Hellsten, Y., Kjær, M., Kujala, U. M., Rhodes, R. E., Pike, E. C. J., Skinner, T. & 6 others, Skovgaard, T., Troelsen, J., Tulle, E., Tully, M. A., van Uffelen, J. G. Z. & Viña, J., 2019, In: British Journal of Sports Medicine. 53, 14, p. 856-858 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Correction for non-rigid movement artefacts in calcium imaging using local-global optical flow and PCA-based templates

    Brazhe, A., Fordsmann, J. & Lauritzen, Martin, Apr 2017, In: Journal of Cerebral Blood Flow and Metabolism. 37, S1, p. 360-361 PS04-077.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  20. Published

    Cortical spreading ischaemia is a novel process involved in ischaemic damage in patients with aneurysmal subarachnoid haemorrhage

    Dreier, J. P., Major, S., Manning, A., Woitzik, J., Drenckhahn, C., Steinbrink, J., Tolias, C., Oliveira-Ferreira, A. I., Fabricius, M., Hartings, J. A., Vajkoczy, P., Lauritzen, M., Dirnagl, U., Bohner, G., Strong, A. J., COSBID study group, Dreier, J. P., Major, S., Manning, A., Woitzik, J. & 12 others, Drenckhahn, C., Steinbrink, J., Tolias, C., Oliveira-Ferreira, A. I., Fabricius, M., Hartings, J. A., Vajkoczy, P., Lauritzen, Martin, Dirnagl, U., Bohner, G., Strong, A. J. & Lauritzen, M., 2009, In: Brain. 132, Pt 7, p. 1866-81 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Corticosteroid administration alters the mechanical properties of isolated collagen fascicles in rat-tail tendon

    Haraldsson, B. T., Aagaard, P., Crafoord-Larsen, D., Kjær, Michael & Magnusson, Stig Peter, 2009, In: Scandinavian Journal of Medicine & Science in Sports Online. 19, 5, p. 621-6 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Corticosteroid injection is the best treatment in plantar fasciitis if combined with controlled training

    Johannsen, F. E., Herzog, R. B., Malmgaard-Clausen, N. M., Hoegberget-Kalisz, M., Magnusson, Stig Peter & Kjær, Michael, 2019, In: Knee Surgery, Sports Traumatology, Arthroscopy. 27, 1, p. 5-12

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Corticosteroid injections, eccentric decline squat training and heavy slow resistance training in patellar tendinopathy

    Kongsgaard, M., Kovanen, V., Aagaard, P., Doessing, S., Hansen, P., Laursen, A. H., Kaldau, N. C., Kjær, Michael & Magnusson, S. P., 2009, In: Scandinavian Journal of Medicine & Science in Sports. 19, 6, p. 790-802 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published
  25. Published

    Crystal structure of the Bloom's syndrome helicase indicates a role for the HRDC domain in conformational changes

    Newman, J. A., Savitsky, P., Allerston, C. K., Bizard, A. H., Özer, Ö., Sarlós, K., Liu, Ying, Pardon, E., Steyaert, J., Hickson, Ian David & Gileadi, O., 2015, In: Nucleic Acids Research. 43, 10, p. 5221-35 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Cyclin E overexpression in the Drosophila accessory gland induces tissue dysplasia

    Molano-Fernández, M., Hickson, Ian David & Herranz, Hector, 2023, In: Frontiers in Cell and Developmental Biology. 10, 992253.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Cyclosporine A, FK506, and NIM811 ameliorate prolonged CBF reduction and impaired neurovascular coupling after cortical spreading depression

    Hansen, H. P., Witgen, B. M., Rasmussen, P. & Lauritzen, Martin, 2011, In: Journal of Cerebral Blood Flow and Metabolism. 31, 7, p. 1588-98 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Cytoplasmic Citrate Flux Modulates the Immune Stimulatory NKG2D Ligand MICA in Cancer Cells

    Møller, S. H., Mellergaard, M., Madsen, M., Bermejo, A. V., Jepsen, Stine Dam, Hansen, M. H., Høgh, R. I., Aldana, Blanca, Desler, Claus, Rasmussen, Lene Juel, Sustarsic, E. G., Gerhart-Hines, Zach, Daskalaki, E., Wheelock, C. E., Hiron, T. K., Lin, D., O'Callaghan, C. A., Wandall, Hans H., Andresen, Lars & Skov, Søren, 2020, In: Frontiers in Immunology. 11, 22 p., 1968.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Cytosolic self-DNA—A potential source of chronic inflammation in aging

    Akbari, M., Shanley, D. P., Bohr, Vilhelm & Rasmussen, Lene Juel, 2021, In: Cells. 10, 12, 3544.

    Research output: Contribution to journalReviewResearchpeer-review

  30. Published

    DNA Damage Signaling Instructs Polyploid Macrophage Fate in Granulomas

    Herrtwich, L., Nanda, I., Evangelou, K., Nikolova, T., Horn, V., Sagar, Erny, D., Stefanowski, J., Rogell, L., Klein, C., Gharun, K., Follo, M., Seidl, M., Kremer, B., Muenke, N., Senges, J., Fliegauf, M., Aschman, T., Pfeifer, D., Sarrazin, S. & 18 others, Sieweke, M. H., Wagner, D., Dierks, C., Haaf, T., Ness, T., Zaiss, M. M., Voll, R. E., Deshmukh, S. D., Prinz, M., Goldmann, T., Hoelscher, C., Hauser, A. E., Lopez-Contreras, Andres, Gruen, D., Gorgoulis, V., Diefenbach, A., Henneke, P. & Triantafyllopoulou, A., 17 Nov 2016, In: Cell. 167, 5, p. 1264–1280.e18

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    DNA Damage, DNA Repair, Aging, and Neurodegeneration

    Maynard, S., Fang, E. F., Scheibye-Knudsen, Morten, Croteau, D. L. & Bohr, Vilhelm, Oct 2015, In: Cold Spring Harbor Perspectives in Medicine. 5, 10, a025130.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    DNA damage response, bioenergetics, and neurological disease: the challenge of maintaining brain health in an aging human population

    Rasmussen, Lene Juel, Shiloh, Y., Bergersen, L. H., Sander, M., Bohr, Vilhelm & Tønjum, T., Oct 2013, In: Mechanisms of Ageing and Development. 134, 10, p. 427-33 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    DNA damage-inducible SUMOylation of HERC2 promotes RNF8 binding via a novel SUMO-binding Zinc finger

    Danielsen, J. M. R., Povlsen, L. K., Villumsen, B. H., Streicher, W., Nilsson, Jakob, Wikström, M., Bekker-Jensen, Simon Holst & Mailand, Niels, 2012, In: Journal of Cell Biology. 197, 2, p. 179-87 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    DNA mismatch repair and its many roles in eukaryotic cells

    Liu, D., Keijzers, G. & Rasmussen, Lene Juel, Jul 2017, In: Mutation Research - Reviews in Mutation Research. 773, p. 174-187 14 p.

    Research output: Contribution to journalReviewResearchpeer-review

  35. Published

    DNA replication stress and its impact on chromosome segregation and tumorigenesis

    Zhang, B. N., Bueno Venegas, A., Hickson, Ian David & Chu, W. K., 2019, In: Seminars in Cancer Biology. 55, p. 61-69

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    DVC1 (C1orf124) is a DNA damage-targeting p97 adaptor that promotes ubiquitin-dependent responses to replication blocks

    Mosbech, A., Gibbs-Seymour, I., Kagias, K., Thorslund, T., Beli, P., Povlsen, L., Nielsen, S. V., Smedegaard, S., Sedgwick, G., Lukas, Claudia, Hartmann-Petersen, Rasmus, Lukas, Jiri, Choudhary, Chunaram, Pocock, R. D. J., Bekker-Jensen, Simon Holst & Mailand, Niels, 2012, In: Nature Structural and Molecular Biology. 19, 11, p. 1084-92 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    Defective mitochondrial respiration, altered dNTP pools and reduced AP endonuclease 1 activity in peripheral blood mononuclear cells of Alzheimer's disease patients

    Maynard, S., Hejl, Anne-Mette, Dinh, T. T. S., Keijzers, G., Hansen, Åse Marie, Desler, Claus, Moreno-Villanueva, M., Bürkle, A., Rasmussen, Lene Juel, Waldemar, Gunhild & Bohr, Vilhelm, Oct 2015, In: Aging. 7, 10, p. 793-815 23 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    Detecting user experience issues from mHealth apps that support stroke caregiver needs: an analysis of user reviews

    Lobo, E. H., Abdelrazek, M., Frølich, Anne, Rasmussen, Lene Juel, Livingston, P. M., Islam, S. M. S., Kensing, Finn & Grundy, J., 2023, In: Frontiers in Public Health. 11, 9 p., 1027667.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Detection of Ultrafine Anaphase Bridges

    Bizard, A. H., Nielsen, Christian Friberg & Hickson, Ian David, 2018, Genome Instability: Methods and Protocols. Springer, Vol. 1672. p. 495-508 14 p. (Methods in molecular biology (Clifton, N.J.)).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  40. Published

    Determining the functional significance of mismatch repair gene missense variants using biochemical and cellular assays

    Heinen, C. D. & Rasmussen, Lene Juel, Jul 2012, In: Hereditary Cancer in Clinical Practice. 10, 1, p. 9

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    Developing T lymphocytes are uniquely sensitive to a lack of topoisomerase III alpha

    Mönnich, M., Hess, I., Wiest, W., Bachrati, C., Hickson, Ian David, Schorpp, M. & Boehm, T., Sep 2010, In: European Journal of Immunology. 40, 9, p. 2379-84 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    Development and evaluation of human AP endonuclease inhibitors in melanoma and glioma cell lines

    Mohammed, M. Z., Vyjayanti, V. N., Laughton, C. A., Dekker, L. V., Fischer, P. M., Wilson, D. M., Abbotts, R., Shah, S., Patel, P. M., Hickson, Ian David & Madhusudan, S., 15 Feb 2011, In: British Journal of Cancer Management. 104, 4, p. 653-63 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    Development of a fiber-based microfluidic flow cytometry platform using viscoelastic fluids for polydisperse particle suspensions

    Serhatlioglu, M., Jensen, E. A., Niora, M., Hansen, A. T., Nielsen, Christian Friberg, Theresia Jansman, M. M., Hosta-Rigau, L., Dziegiel, Morten Hanefeld, Berg-Sørensen, K., Hickson, Ian David & Kristensen, A., 2022, In: Proceedings of SPIE - The International Society for Optical Engineering. 12198, 9 p., 1219802.

    Research output: Contribution to journalConference articleResearchpeer-review

  44. Published

    Differential expression of hMLH1 in sporadic human colorectal cancer tumors and distant metastases

    Larsen, N. B., Heiberg Engel, P. J., Rasmussen, M. & Rasmussen, Lene Juel, 2009, In: Acta Pathologica Microbiologica et Immunologica Scandinavica. 117, 11, p. 839-48 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    Differential satellite cell density of type I and II fibres with lifelong endurance running in old men

    Mackey, Abigail, Karlsen, Anders, Couppé, Christian, Mikkelsen, U. R., Nielsen, R. H., Magnusson, Stig Peter & Kjær, Michael, Mar 2014, In: Acta Physiologica (Print). 210, 3, p. 612-27 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    Differentially activated macrophages orchestrate myogenic precursor cell fate during human skeletal muscle regeneration

    Saclier, M., Yacoub-Youssef, H., Mackey, Abigail, Arnold, L., Ardjoune, H., Magnan, M., Sailhan, F., Chelly, J., Pavlath, G. K., Mounier, R., Kjær, Michael & Chazaud, B., Feb 2013, In: Stem Cells. 31, 2, p. 384-96 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    Disease-causing mutations in the XIAP BIR2 domain impair NOD2-dependent immune signalling

    Damgaard, R. B., Fiil, Berthe Katrine, Speckmann, C., Yabal, M., Stadt, U. Z., Bekker-Jensen, Simon Holst, Jost, P. J., Ehl, S., Mailand, Niels & Gyrd-Hansen, Mads, 1 Jul 2013, In: E M B O Journal. 5, p. 1278-1295 18 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    Disturbed mitochondrial function restricts glutamate uptake in the human Müller glia cell line, MIO-M1

    Vohra, Rupali, Gurubaran, I. S., Henriksen, U., Bergersen, L. H., Rasmussen, Lene Juel, Desler, C., Jensen, Dorte Skytt & Kolko, Miriam, 2017, In: Mitochondrion. 36, p. 52-59

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    Dual Properties of Lactate in Müller Cells: The Effect of GPR81 Activation

    Vohra, Rupali, Aldana, Blanca, Waagepetersen, Helle S., Bergersen, L. H. & Kolko, Miriam, 1 Mar 2019, In: Investigative Ophthalmology & Visual Science. 60, 4, p. 999-1008 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    Duplex DNA and BLM regulate gate opening by the human TopoIIIα-RMI1-RMI2 complex

    Bakx, J. A. M., Biebricher, A. S., King, G. A., Christodoulis, P., Sarlós, K., Bizard, A. H., Hickson, Ian David, Wuite, G. J. L. & Peterman, E. J. G., 2022, In: Nature Communications. 13, 1, 584.

    Research output: Contribution to journalJournal articleResearchpeer-review

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