- Published
Spatial Transcriptomics Reveals Genes Associated with Dysregulated Mitochondrial Functions and Stress Signaling in Alzheimer Disease
Navarro, J. F., Croteau, D. L., Jurek, A., Andrusivova, Z., Yang, B., Wang, Y., Ogedegbe, B., Riaz, T., Støen, M., Desler, Claus, Rasmussen, Lene Juel, Tønjum, T., Galas, M. C., Lundeberg, J. & Bohr, Vilhelm, 2020, In: iScience. 23, 10, 42 p., 101556.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Spinal dorsal horn astrocytes release GABA in response to synaptic activation
Christensen, R. K., Delgado-Lezama, R., Russo, R. E., Lind, Barbara Lykke, Alcocer, E. L., Rath, Martin Fredensborg, Fabbiani, G., Schmitt, Nicole, Lauritzen, Martin, Petersen, A. V., Carlsen, Eva Maria Meier & Perrier, Jean-Francois Marie, 2018, In: The Journal of Physiology. 596, 20, p. 4983-4994 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Spontaneous astrocytic Ca2+ activity abounds in electrically suppressed ischemic penumbra of aged mice
Fordsmann, J. C., Murmu, R. P., Cai, Changsi, Brazhe, A., Thomsen, Kirsten Joan, Zambach, S. A., wbh615, wbh615, Lind, Barbara Lykke & Lauritzen, Martin, 2019, In: Glia. 67, 1, p. 37-52 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Spontaneous calcium waves in Bergman glia increase with age and hypoxia and may reduce tissue oxygen
Mathiesen, C., Brazhe, A., Thomsen, Kirsten Joan & Lauritzen, Martin, 2013, In: Journal of Cerebral Blood Flow and Metabolism. 33, p. 161-9 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Spreading Depression, Spreading Depolarizations, and the Cerebral Vasculature
Ayata, C. & Lauritzen, Martin, Jul 2015, In: Physiological Reviews. 95, 3, p. 953-993 41 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Stalled replication forks generate a distinct mutational signature in yeast
Larsen, N. B., Liberti, S. E., Vogel, Ivan, Jorgensen, S. W., Hickson, Ian David & Mankouri, H. W., 2017, In: Proceedings of the National Academy of Sciences of the United States of America. 114, 36, p. 9665-9670Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Stimulation-induced increases in cerebral blood flow and local capillary vasoconstriction depend on conducted vascular responses
Cai, Changsi, Fordsmann, J. C., Jensen, S. H., Gesslein, B., wbh615, wbh615, Hald, B. O., Zambach, S. A., Larsen, Birger Brodin & Lauritzen, Martin, 2018, In: Proceedings of the National Academy of Sciences of the United States of America. 115, 25, p. E5796-E5804 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Structural Analysis of a Complex between Small Ubiquitin-like Modifier 1 (SUMO1) and the ZZ Domain of CREB-binding Protein (CBP/p300) Reveals a New Interaction Surface on SUMO
Diehl, C., Akke, M., Bekker-Jensen, Simon Holst, Mailand, Niels, Streicher, W. & Wikström, M., 10 Jun 2016, In: Journal of Biological Chemistry. 291, 24, p. 12658-12672 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Structural And Physiological Changes In Chronically overused Achilles tendons
Langberg, Henning, Pingel, Jessica, Fredberg, U., Qvortrup, Klaus, Overgaard, J. & Kjær, Michael, May 2012, In: Medicine and Science in Sports and Exercise. 44, p. 116 1 p.Research output: Contribution to journal › Conference article › Research › peer-review
- Published
Structural and mechanistic insight into Holliday-junction dissolution by topoisomerase IIIα and RMI1
Bocquet, N., Bizard, A. H., Abdulrahman, W., Larsen, N. B., Faty, M., Cavadini, S., Bunker, R. D., Kowalczykowski, S. C., Cejka, P., Hickson, Ian David & Thomä, N. H., Mar 2014, In: Nature Structural and Molecular Biology. 21, 3, p. 261-8 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Structural, biochemical, cellular, and functional changes in skeletal muscle extracellular matrix with aging
Kragstrup, T. W., Kjær, Michael & Mackey, Abigail, 2011, In: Scandinavian Journal of Medicine & Science in Sports. 21, 6, p. 749-57 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Structure-specific endonucleases: guardians of fragile site stability
Minocherhomji, S. & Hickson, Ian David, May 2014, In: Trends in Cell Biology. 24, 5, p. 321-327 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Sub-Clinical Cognitive Decline and Resting Cerebral Blood Flow in Middle Aged Men
Henriksen, O. M., Hansen, N. L., Osler, Merete, Mortensen, Erik Lykke, Hallam, D. M., Pedersen, E. T., Chappell, M., Lauritzen, Martin & Rostrup, E., 2017, In: PLOS ONE. 12, 1, 15 p., e0169912.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Subclinical cognitive decline in middle-age is associated with reduced task-induced deactivation of the brain's default mode network
Hansen, N. L., Lauritzen, Martin, Mortensen, Erik Lykke, Osler, Merete, Avlund, K., Fagerlund, Birgitte & Rostrup, E., Sep 2014, In: Human Brain Mapping. 35, 9, p. 4488-98 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Subjective sleep quality and daytime sleepiness in late midlife and their association with age-related changes in cognition
Waller, K. L., Mortensen, Erik Lykke, Avlund, K., Osler, Merete, Fagerlund, Birgitte, Lauritzen, Martin & Jennum, Poul, Jan 2016, In: Sleep Medicine. 17, p. 165-73 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Supraphysiological protection from replication stress does not extend mammalian lifespan
Albers, E., Avram, Alexandra Ioana, Sbroggio, M., Fernandez-Capetillo, O. & Lopez-Contreras, Andres, 2020, In: Aging. 12, 7, p. 5612-5624 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Synthesis and SAR studies of 5-(pyridin-4-yl)-1,3,4-thiadiazol-2-amine derivatives as potent inhibitors of Bloom helicase
Rosenthal, A. S., Dexheimer, T. S., Gileadi, O., Nguyen, G. H., Chu, W. K., Hickson, Ian David, Jadhav, A., Simeonov, A. & Maloney, D. J., 15 Oct 2013, In: Bioorganic & Medicinal Chemistry Letters. 23, 20, p. 5660-6 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Systems modelling predicts chronic inflammation and genomic instability prevent effective mitochondrial regulation during biological ageing
Guimera, A. M., Clark, P., Wordsworth, J., Anugula, Sharath, Rasmussen, Lene Juel & Shanley, D. P., 2022, In: Experimental Gerontology. 166, 9 p., 111889.Research output: Contribution to journal › Review › Research › peer-review
- Published
Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass
Povlsen, L. K., Beli, P., Wagner, S. A., Poulsen, S. L., Sylvestersen, K. B., Poulsen, J. W., Nielsen, Michael Lund, Bekker-Jensen, Simon Holst, Mailand, Niels & Choudhary, Chunaram, Oct 2012, In: Nature Cell Biology. 14, 10, p. 1089-98 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
THE EXTRACELLULAR MATRIX AND ITS ADAPTATIONS TO CHANGE IN CHRONIC LOADING
Kjær, Michael, Magnusson, P., Suetta, Charlotte, Dossing, S., Heinemeier, K., Schjerling, Peter, Hansen, M., Kongsgaard, M., Mackey, Abigail, Andersen, J. L. & Langberg, Henning, 2009, p. 62-62.Research output: Contribution to conference › Conference abstract for conference › Research › peer-review
- Published
TIP60 in aging and neurodegeneration
Li, Zhiquan & Rasmussen, Lene Juel, 2020, In: Ageing Research Reviews. 64, 101195.Research output: Contribution to journal › Review › Research › peer-review
- Published
TRAIP is a PCNA-binding ubiquitin ligase that protects genome stability after replication stress
Hoffmann, Saskia, Smedegaard, S., Nakamura, K., Mortuza, G. B., Räschle, M., Ibañez de Opakua, A., Oka, Y., Feng, Y., Blanco, F. J., Mann, Matthias, Montoya, Guillermo, Groth, Anja, Bekker-Jensen, Simon Holst & Mailand, Niels, 4 Jan 2016, In: The Journal of Cell Biology. 212, 1, p. 63-75Research output: Contribution to journal › Journal article › Research › peer-review
- Published
TRIP12 and UBR5 Suppress Spreading of Chromatin Ubiquitylation at Damaged Chromosomes
Gudjónsson, Thorkell, Altmeyer, M. F., Savic, V., Toledo Lazaro, L. I., Dinant, C., Grøfte, M., Bartkova, J., Poulsen, M., Oka, Y., Bekker-Jensen, Simon Holst, Mailand, Niels, Neumann, B., Heriche, J., Shearer, R., Saunders, D., Bartek, J., Lukas, Jiri & Lukas, Claudia, 17 Aug 2012, In: Cell. 150, 4, p. 697-709 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Tendon and skeletal muscle matrix gene expression and functional responses to immobilisation and rehabilitation in young males: Effect of growth hormone administration
Boesen, A. P., Dideriksen, K., Couppé, Christian, Magnusson, P., Schjerling, Peter, Boesen, M., Kjær, Michael & Langberg, Henning, 30 Sep 2013, In: Journal of Physiology. p. 6039-6052Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Tendon blood flow, angiogenesis, and tendinopathy pathogenesis
Merkel, M. F. R., Hellsten, Ylva, Magnusson, Stig Peter & Kjær, Michael, 2021, In: Translational Sports Medicine. 4, 6, p. 756-771 16 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Tendon collagen synthesis declines with immobilization in elderly humans: no effect of anti-inflammatory medication
Dideriksen, K., Boesen, A. P., Reitelseder, S., Couppé, C., Svensson, R., Schjerling, P., Magnusson, Stig Peter, Holm, L. & Kjær, Michael, Feb 2017, In: Journal of Applied Physiology. 122, 2, p. 273-282 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Tendon properties in a mouse model of severe osteogenesis imperfecta
Sinkam, L., Boraschi-Diaz, I., Svensson, R. B., Kjær, Michael, Komarova, S. V., Bergeron, R., Rauch, F. & Veilleux, L. N., 2023, In: Connective Tissue Research. 64, 3, p. 285-293Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Tendon protein synthesis rate in classic Ehlers-Danlos patients can be stimulated with insulin-like growth factor-I
Nielsen, R. H., Holm, L., Jensen, J. K., Heinemeier, K. M., Remvig, L. & Kjær, Michael, 1 Oct 2014, In: Journal of Applied Physiology. 117, 7, p. 694-698 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Tensile force transmission in human patellar tendon fascicles is not mediated by glycosaminoglycans
Svensson, R. B., Hassenkam, Tue, Hansen, P., Kjær, Michael & Magnusson, Stig Peter, 2011, In: Connective Tissue Research. 52, 5, p. 415-21 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The "enemies within": regions of the genome that are inherently difficult to replicate
Bhowmick, Rahul & Hickson, Ian David, 2017, In: F1000Research. 6, 7 p., 666.Research output: Contribution to journal › Review › Research › peer-review
- Published
The Detection and Analysis of Chromosome Fragile Sites
Bjerregaard, Victoria Alexandra, Özer, Ö., Hickson, Ian David & Liu, Ying, 2018, Genome Instability: Methods and Protocols. Springer, Vol. 1672. p. 471-482 12 p. (Methods in molecular biology (Clifton, N.J.)).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
The Dissolution of Double Holliday Junctions
Bizard, A. H. & Hickson, Ian David, 1 Jul 2014, In: Cold Spring Harbor perspectives in biology. 6, p. 1-16 16 p., a016477.Research output: Contribution to journal › Review › Research › peer-review
- Published
The Effect of Aging and Mechanical Loading on the Metabolism of Articular Cartilage
Jørgensen, A. E. M., Kjær, Michael & Heinemeier, K. M., Apr 2017, In: Journal of Rheumatology. 44, 4, p. 410-417Research output: Contribution to journal › Review › Research › peer-review
- Published
The Escherichia coli Tus-Ter replication fork barrier causes site-specific DNA replication perturbation in yeast
Larsen, N. B., Sass, E., Suski, C., Mankouri, H. W. & Hickson, Ian David, 2014, In: Nature Communications. 5, p. 1-10 10 p., 3574.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Journal of Cerebral Blood Flow and Metabolism clinical, inaugural issue
Lauritzen, Martin & Dirnagl, U., Jan 2016, In: Journal of Cerebral Blood Flow and Metabolism. 36, 1, p. 3-3Research output: Contribution to journal › Editorial › Research
- Published
The NAD+-mitophagy axis in healthy longevity and in artificial intelligence-based clinical applications
Aman, Y., Frank, J., Lautrup, S. H., Matysek, A., Niu, Z., Yang, G., Shi, L., Bergersen, L. H., Storm-Mathisen, J., Rasmussen, Lene Juel, Bohr, Vilhelm, Nilsen, H. & Fang, E. F., 2020, In: Mechanisms of Ageing and Development. 185, 111194.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Ruptured Achilles Tendon Elongates for 6 Months After Surgical Repair Regardless of Early or Late Weightbearing in Combination With Ankle Mobilization: A Randomized Clinical Trial
Eliasson, P., Agergaard, A., Couppe, C., Svensson, R., Hoeffner, R., Warming, S., Warming, N., Holm, C., Jensen, M. H., Krogsgaard, Michael R., Kjær, Michael & Magnusson, Stig Peter, 2018, In: American Journal of Sports Medicine. 46, 10, p. 2492-2502Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Ubiquitin Ligase XIAP Recruits LUBAC for NOD2 Signaling in Inflammation and Innate Immunity
Damgaard, R. B., Nachbur, U., Yabal, M., Wong, W. W., Fiil, Berthe Katrine, Kastirr, M., Rieser, E., Rickard, J. A., Bankovacki, A., Peschel, C., Ruland, J., Bekker-Jensen, Simon Holst, Mailand, Niels, Kaufmann, T., Strasser, A., Walczak, H., Silke, J., Jost, P. J. & Gyrd-Hansen, Mads, 2012, In: Molecular Cell. 46, 6, p. 746-58 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The ZGRF1 Helicase Promotes Recombinational Repair of Replication-Blocking DNA Damage in Human Cells
Brannvoll, A., Xue, X., Kwon, Y., Kompocholi, Smaragda, Simonsen, Anne Katrine Wrist, Bagge, Keerthana Stine Viswalingam, Gonzalez, L., Hickson, Ian David, Østergaard, Vibe Hallundbæk, Mankouri, H. W., Sung, P. & Lisby, Michael, 2020, In: Cell Reports. 32, 1, 25 p., 107849.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The anabolis potential of dietary protein intake on skeletal muscle is prolonged by prior light-load exercise
Bechshøft, R., Dideriksen, K. J., Reitelseder, S., Scheike, Thomas, Kjær, Michael & Holm, L., 2013, In: Clinical Nutrition. 32, 2, p. 236-244Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The battle to keep or lose skeletal muscle with ageing
Kjær, Michael & Jespersen, J. G., 2009, In: Journal of Physiology. 587, Pt 1, p. 1-2 2 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The breaking and making of healthy adult human skeletal muscle in vivo
Mackey, Abigail & Kjær, Michael, 2017, In: Skeletal Muscle. 7, 18 p., 24.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The challenges of human population ageing
Sander, M., Oxlund, Bjarke, Jespersen, Astrid Pernille, Krasnik, Allan, Mortensen, Erik Lykke, Westendorp, Rudi GJ & Rasmussen, Lene Juel, Mar 2015, In: Age and Ageing. 44, 2, p. 185-7 3 p.Research output: Contribution to journal › Journal article › Communication
- Published
The changing brain--insights into the mechanisms of neural and behavioral adaptation to the environment
Bergersen, L. H., Bramham, C. R., Hugdahl, K., Sander, M. & Storm-Mathisen, J., 5 Sep 2013, In: Neuroscience. 247, p. 412-22 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The deubiquitylating enzyme USP44 counteracts the DNA double-strand break response mediated by the RNF8 and RNF168 ubiquitin ligases
Mosbech, A., Lukas, Claudia, Bekker-Jensen, Simon Holst & Mailand, Niels, 24 Apr 2013, In: Journal of Biological Chemistry. 288, p. 16579-16587 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The effect of 4 months exercise training on systemic biomarkers of cartilage and bone turnover in hip osteoarthritis patients
Ellegaard, M., Bieler, T., Beyer, N., Kjær, Michael & Jørgensen, Niklas Rye, 2020, In: Translational Sports Medicine. 3, 1, p. 16-25Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The effect of acute exercise on collagen turnover in human tendons: influence of prior immobilization period
Mørch, L. S., Pingel, Jessica, Boesen, M., Kjær, Michael & Langberg, Henning, 2013, In: European Journal of Applied Physiology. 113, 2, p. 449-455 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The effect of mitochondrial dysfunction on cytosolic nucleotide metabolism
Desler, Claus, Lykke, A. & Rasmussen, Lene Juel, 1 Jan 2010, In: Journal of Nucleic Acids. 2010Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The effect of resistance exercise upon age-related systemic and local skeletal muscle inflammation
Ziegler, A. K., Jensen, S. M., Schjerling, P., Mackey, Abigail, Andersen, J. L. & Kjær, Michael, 2019, In: Experimental Gerontology. 121, p. 19-32Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The effect of strength training, recreational soccer and running exercise on stretch-shortening cycle muscle performance during countermovement jumping
Jakobsen, M. D., Sundstrup, E., Randers, M. B., Kjær, Michael, Andersen, L. L., Krustrup, P. & Aagaard, P., 2012, In: Human Movement Science. 31, 4, p. 970-986 17 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Protocol for the combined cardiometabolic deep phenotyping and registry-based 20-year follow-up study of the Inter99 cohort
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