Damage and Repair

  1. Published

    A novel method for determining human ex vivo submaximal skeletal muscle mitochondrial function

    Hey-Mogensen, M., Gram, M., Jensen, M. B., Lund, M. T., Hansen, C. N., Scheibye-Knudsen, Morten, Bohr, Vilhelm & Dela, Flemming, 1 Sep 2015, In: The Journal of Physiology. 593, 17, p. 3991-4010 20 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    A novel splice variant of Elp3/Kat9 regulates mitochondrial tRNA modification and function

    Boutoual, R., Jo, H., Heckenbach, Indra John, Tiwari, R., Kasler, H., Lerner, C. A., Shah, S., Schilling, B., Calvanese, V., Rardin, M. J., Scheibye-Knudsen, Morten & Verdin, E., 2022, In: Scientific Reports. 12, 14804.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    A rapid and cell-free assay to test the activity of lynch syndrome-associated MSH2 and MSH6 missense variants

    Drost, M., Zonneveld, J. B. M., van Hees, S., Rasmussen, Lene Juel, Hofstra, R. M. W. & de Wind, N., 2012, In: Human Mutation. 33, 3, p. 488-94 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    A short G1 phase imposes constitutive replication stress and fork remodelling in mouse embryonic stem cells

    Ahuja, A. K., Jodkowska, K., Teloni, F., Bizard, A. H., Zellweger, R., Herrador, R., Ortega, S., Hickson, Ian David, Altmeyer, M., Mendez, J. & Lopes, M., Feb 2016, In: Nature Communications. 7, 11 p., 10660.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    A simple DNA recombination screening method by RT-PCR as an alternative to Southern blot

    Albers, E., Sbroggiò, M., Martin Gonzalez, Javier, Avram, Alexandra Ioana, Munk, S. & Lopez-Contreras, Andres, Jun 2017, In: Transgenic Research. 26, 3, p. 429-434 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    A small interfering RNA screen of genes involved in DNA repair identifies tumor-specific radiosensitization by POLQ knockdown

    Higgins, G. S., Prevo, R., Lee, Y., Helleday, T., Muschel, R. J., Taylor, S., Yoshimura, M., Hickson, Ian David, Bernhard, E. J. & McKenna, W. G., Apr 2010, In: Cancer Research. 70, 7, p. 2984-93 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    ARDD 2020: from aging mechanisms to interventions

    Mkrtchyan, G. V., Abdelmohsen, K., Andreux, P., Bagdonaite, I., Barzilai, N., Brunak, S., Cabreiro, F., Cabo, R. D., Campisi, J., Cuervo, A. M., Demaria, M., Ewald, C. Y., Fang, E. F., Faragher, R., Ferrucci, L., Freund, A., Silva-García, C. G., Georgievskaya, A., Gladyshev, V. N., Glass, D. J. & 46 others, Gorbunova, V., Grey, A. D., He, W. W., Hoeijmakers, J., Hoffmann, Eva, Horvath, S., Houtkooper, R. H., Jensen, Majken Karoline, Jensen, M. B., Kane, A., Kassem, Moustapha Saad El-Deen, Keizer, P. D., Kennedy, B., Karsenty, G., Lamming, D. W., Lee, K. F., MacAulay, Nanna, Mamoshina, P., Mellon, J., Molenaars, M., Moskalev, A., Mund, Andreas, Niedernhofer, L., Osborne, Brenna, Pak, H. H., Parkhitko, A., Raimundo, N., Rando, T. A., Rasmussen, Lene Juel, Reis, C., Riedel, C. G., Franco-Romero, A., Schumacher, B., Sinclair, D. A., Suh, Y., Taub, P. R., Toiber, D., Treebak, Jonas Thue, Valenzano, D. R., Verdin, E., Vijg, J., Young, S., Zhang, L., Bakula, Daniela Janina, Zhavoronkov, A. & Scheibye-Knudsen, Morten, 2020, In: Aging. 12, 24, p. 24486-24503 18 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    ATP induce an increase in intracellular Ca2+ in pericytes of the blood-brain barrier

    Jensen, S. H., Helms, H. C. C., Jessen, S. B., Lauritzen, Martin, Waagepetersen, Helle S. & Larsen, Birger Brodin, 2 Nov 2015.

    Research output: Contribution to conferencePosterResearchpeer-review

  9. Published

    ATP induce intracellular calcium rises in cultures of primary brain pericytes

    Jensen, S. H., Helms, H. C. C., Jessen, S. B., Lauritzen, Martin, Waagepetersen, Helle S. & Larsen, Birger Brodin, Jun 2016.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  10. Published

    ATP induces contraction of cultured brain capillary pericytes, via activation of P2Y type purinergic receptors

    Hørlyck, S., Cai, Changsi, Helms, H. C., Lauritzen, Martin & Larsen, Birger Brodin, 2021, In: American Journal of Physiology: Heart and Circulatory Physiology. 320, p. H699–H712 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    ATR Prohibits Replication Catastrophe by Preventing Global Exhaustion of RPA

    Toledo Lazaro, L. I., Altmeyer, M., Rask, M., Lukas, Claudia, Larsen, D. H., Povlsen, L. K., Bekker-Jensen, Simon Holst, Mailand, Niels, Bartek, J. & Lukas, Jiri, 21 Nov 2013, In: Cell. 155, 5, p. 1088-1103 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    ATR expands embryonic stem cell fate potential in response to replication stress

    Atashpaz, S., Samadi Shams, S., Martin Gonzalez, Javier, Sebestyén, E., Arghavanifard, N., Gnocchi, A., Albers, E., Minardi, S., Faga, G., Soffientini, P., Allievi, E., Cancila, V., Bachi, A., Fernández-Capetillo, Ó., Tripodo, C., Ferrari, F., Lopez-Contreras, Andres & Costanzo, V., 2020, In: eLife. 9, e54756.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    ATRX-Deficient High-Grade Glioma Cells Exhibit Increased Sensitivity to RTK and PDGFR Inhibitors

    Pladevall Morera, David, Castejón-Griñán, M., Aguilera, P., Gaardahl, K., Ingham, Andreas, Brosnan-Cashman, J. A., Meeker, A. K. & Lopez-Contreras, Andres, 2022, In: Cancers. 14, 7, 1790.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Accuracy of MRI technique in measuring tendon cross-sectional area

    Couppé, Christian, Svensson, R. B., Elbrønd (Bibs), Vibeke Sødring, Hansen, P., Kjær, Michael & Magnusson, Stig Peter, 2014, In: Clinical Physiology and Functional Imaging. 34, 3, p. 237-241 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Acquired Localized Cutis Laxa due to Increased Elastin Turnover

    Nygaard, R. H., Maynard, S., Schjerling, P., Kjær, M., Qvortrup, Klaus, Bohr, Vilhelm, Rasmussen, Lene Juel, Jemec, Gregor & Heidenheim, M., 14 Jun 2016, In: Case Reports in Dermatology. 8, 1, p. 42-51 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Activated protein synthesis and suppressed protein breakdown signaling in skeletal muscle of critically ill patients

    Jespersen, J. G., Nedergaard, A., Reitelseder, S., Mikkelsen, U. R., Dideriksen, K. J., Agergaard, J., Kreiner, F., Pott, Frank Christian, Schjerling, P. & Kjær, Michael, 2011, In: P L o S One. 6, 3, p. e18090

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Activation of satellite cells and the regeneration of human skeletal muscle are expedited by ingestion of nonsteroidal anti-inflammatory medication

    Mackey, Abigail, Rasmussen, L. K., Kadi, F., Schjerling, Peter, Helmark, I. C., Ponsot, E., Aagaard, P., Durigan, J. L. Q. & Kjær, Michael, 2 Mar 2016, In: FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 30, 6, p. 2266-2281

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Activation of the ATR kinase by the RPA-binding protein ETAA1

    Haahr, Peter Thorlund, Hoffmann, Saskia, Tollenaere, M. A. X., Ho, T., Toledo Lazaro, L. I., Mann, Matthias, Bekker-Jensen, Simon Holst, Räschle, M. & Mailand, Niels, Nov 2016, In: Nature Cell Biology. 18, 11, p. 1196–1207

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Active role of capillary pericytes during stimulation-induced activity and spreading depolarization

    Khennouf, Lila, Gesslein, B., Brazhe, A., Octeau, J. C., Kutuzov, Nikolay, Khakh, B. S. & Lauritzen, Martin, 2018, In: Brain. 141, 7, p. 2032-2046 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Activity-Dependent Calcium, Oxygen, and Vascular Responses in a Mouse Model of Familial Hemiplegic Migraine Type 1

    Khennouf, Lila, Gesslein, B., Lind, Barbara Lykke, van den Maagdenberg, A. M. J. M. & Lauritzen, Martin, Aug 2016, In: Annals of Neurology. 80, 2, p. 219-232

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Activity-dependent increases in local oxygen consumption correlate with post-synaptic currents in the mouse cerebellum in vivo: Calcium, synaptic currents and oxygen

    Mathiesen, C., Caesar, K., Thomsen, Kirsten Joan, Hoogland, T., Witgen, B. M., Brazhe, A. & Lauritzen, Martin, 14 Dec 2011, In: Journal of Neuroscience. 31, 50, p. 18327-37 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Activity-dependent increases in local oxygen consumption correlate with postsynaptic currents in the mouse cerebellum in vivo

    Mathiesen, C., Caesar, K., Thomsen, K. E., Hoogland, T. M., Witgen, B. M., Brazhe, A. & Lauritzen, Martin, 2011, In: Journal of Neuroscience. 31, 50, p. 18327-37 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Acute MUS81 depletion leads to replication fork slowing and a constitutive DNA damage response

    Xing, M., Wang, X., Palmai-Pallag, T., Shen, H., Helleday, T., Hickson, Ian David & Ying, S., 2015, In: OncoTarget. 6, 35, p. 37638-37646 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Acute fatigue impairs neuromuscular activity of anterior cruciate ligament-agonist muscles in female team handball players

    Zebis, M. K., Bencke, J., Andersen, L. L., Alkjær, Tine, Suetta, Charlotte, Mortensen, P., Kjær, Michael, Aagaard, P., Zebis, M. K., Bencke, J., Andersen, L. L., Alkjaer, T., Suetta, C., Mortensen, P., Kjær, Michael & Aagaard, P., 2011, In: Scandinavian Journal of Medicine & Science in Sports Online. 21, 6, p. 833-40 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Acute inactivation of the replicative helicase in human cells triggers MCM8-9-dependent DNA synthesis

    Natsume, T., Nishimura, K., Minocherhomji, S., Bhowmick, Rahul, Hickson, Ian David & Kanemaki, M. T., 2017, In: Genes & Development. 31, 8, p. 816-829 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

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