Damage and Repair

  1. Published

    γ-Aminobutyric acid modulates local brain oxygen consumption and blood flow in rat cerebellar cortex (Journal of Cerebral Blood Flow and Metabolism (2008) 28, (906-915) DOI: 10.1038/sj.jcbfm.9600581)

    Caesar, K., Offenhauser, N. & Lauritzen, Martin, 5 Mar 2009, In: Journal of Cerebral Blood Flow and Metabolism. 29, 3, 1 p.

    Research output: Contribution to journalComment/debateResearchpeer-review

  2. Published

    p38-MK2 signaling axis regulates RNA metabolism after UV-light-induced DNA damage

    Borisova, M. E., Voigt, A., Tollenaere, M. A. X., Sahu, S. K., Juretschke, T., Kreim, N., Mailand, Niels, Choudhary, Chunaram, Bekker-Jensen, Simon Holst, Akutsu, M., Wagner, S. A. & Beli, P., 1 Dec 2018, In: Nature Communications. 9, p. 1-16 16 p., 1017.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    p38- and MK2-dependent signalling promotes stress-induced centriolar satellite remodelling via 14-3-3-dependent sequestration of CEP131/AZI1

    Tollenaere, M. A. X., Villumsen, B. H., Blasius, M., Nielsen, J. C., Wagner, S. A., Bartek, J., Beli, P., Mailand, Niels & Bekker-Jensen, Simon Holst, 30 Nov 2015, In: Nature Communications. 6, p. 1-12 12 p., 10075.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    mHealth applications to support caregiver needs and engagement during stroke recovery: A content review

    Lobo, E. H., Frølich, Anne, Kensing, Finn, Rasmussen, Lene Juel, Livingston, P. M., Grundy, J. & Abdelrazek, M., 2021, In: Research in Nursing and Health. 44, 1, p. 213-225

    Research output: Contribution to journalReviewResearchpeer-review

  5. Published

    Yeast as a model system to study RecQ helicase function

    Ashton, T. M. & Hickson, Ian David, 2010, In: DNA Repair. 9, 3, p. 303-14 11 p.

    Research output: Contribution to journalReviewResearchpeer-review

  6. Published

    White matter lactate: Does it matter?

    Rinholm, J. E. & Bergersen, L. H., 2014, In: Neuroscience. 276, p. 109-116 8 p.

    Research output: Contribution to journalReviewResearchpeer-review

  7. Published

    What is the impact of inflammation on the critical interplay between mechanical signaling and biochemical changes in tendon matrix?

    Kjær, Michael, Bayer, M. L., Eliasson, P. & Heinemeier, K. M., 2013, In: Journal of Applied Physiology. 115, 6, p. 879-883 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    What is the impact of acute inflammation on muscle performance in geriatric patients?

    Karlsen, Anders, Mackey, Abigail, Suetta, Charlotte & Kjær, Michael, 1 Jun 2020, In: Experimental Gerontology. 138, 8 p., 111008.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Vive la radiorésistance! Converging research in radiobiology and biogerontology to enhance human radioresistance for deep space exploration and colonization

    Cortese, F., Klokov, D., Osipov, A., Stefaniak, J., Moskalev, A., Schastnaya, J., Cantor, C., Aliper, A., Mamoshina, P., Ushakov, I., Sapetsky, A., Vanhaelen, Q., Alchinova, I., Karganov, M., Kovalchuk, O., Wilkins, R., Shtemberg, A., Moreels, M., Baatout, S., Izumchenko, E. & 10 others, de Magalhães, J. P., Artemov, A. V., Costes, S. V., Beheshti, A., Mao, X. W., Pecaut, M. J., Kaminskiy, D., Ozerov, I. V., Scheibye-Knudsen, Morten & Zhavoronkov, A., 2018, In: OncoTarget. 9, 18, p. 14692-14722 31 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Visual steady state in relation to age and cognitive function

    Horwitz, A., Dyhr Thomsen, M., Wiegand, I., Horwitz, H., Klemp, Marc Patrick Brag, Nikolic, M., Rask, L., Lauritzen, Martin & Benedek, Krisztina, 2017, In: PLOS ONE. 12, 2, 23 p., e0171859.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Viscoelastic Capillary Flow Cytometry

    Serhatlioglu, M., Jensen, E. A., Niora, M., Hansen, A. T., Nielsen, Christian Friberg, Jansman, M. M. T., Hosta-rigau, L., Dziegiel, Morten Hanefeld, Berg-sørensen, K., Hickson, Ian David & Kristensen, A., 2023, In: Advanced NanoBiomed Research. 3, 2, 2200137.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Variation in the risk of colorectal cancer in families with Lynch syndrome: a retrospective cohort study

    The International Mismatch Repair Consortium, T. I. M. R. C., Jul 2021, In: The Lancet Oncology. 22, 7, p. 1014-1022 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Validation of hippocampal texture for early Alzheimer’s disease detection: generalization to independent cohorts and extrapolation to very early signs of dementia

    Sørensen, L., Igel, Christian, Hansen, N. L., Lauritzen, Martin, Osler, Merete, Rostrup, Egill & Nielsen, Mads, 2014, In: Alzheimer's & Dementia. 10, 4, Supplement, p. P133 1 p.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  14. Published

    Upregulation of the lactate transporter monocarboxylate transporter 1 at the blood-brain barrier in a rat model of attention-deficit/hyperactivity disorder suggests hyperactivity could be a form of self-treatment

    Medin, T., Medin, H., Hefte, M. B., Storm-Mathisen, J. & Bergersen, L. H., 2019, In: Behavioural Brain Research. 360, p. 279-285 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Unaltered lactate and glucose transporter levels in the MPTP mouse model of Parkinson's disease

    Puchades, M., Sogn, C. J., Maehlen, J., Bergersen, L. H. & Gundersen, V., 1 Jan 2013, In: Journal of Parkinson's Disease. 3, 3, p. 371-85 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Ubiquitin-like protein UBL5 promotes the functional integrity of the Fanconi anemia pathway

    Oka, Y., Bekker-Jensen, Simon Holst & Mailand, Niels, 9 Apr 2015, In: E M B O Journal. 34, p. 1385-1398

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Ubiquitin-SUMO Circuitry Controls Activated Fanconi Anemia ID Complex Dosage in Response to DNA Damage

    Gibbs-Seymour, I., Oka, Y., Rajendra, E., Weinert, B. T., Passmore, L. A., Patel, K. J., Olsen, Jesper Velgaard, Choudhary, Chunaram, Bekker-Jensen, Simon Holst & Mailand, Niels, Jan 2015, In: Molecular Cell. 57, 1, p. 150-64 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Ubiquitin and the DNA damage response: a new handle on histones

    Bekker-Jensen, Simon Holst & Mailand, Niels, 1 Sep 2012, In: Cell Cycle. 11, 17, p. 3153 1 p.

    Research output: Contribution to journalComment/debateResearchpeer-review

  19. Published

    UTE T2* mapping of tendinopathic patellar tendons: an MRI reproducibility study

    Agergaard, A. S., Malmgaard-Clausen, N. M., Svensson, R. B., Nybing, J. D., Boesen, Mikael Ploug, Kjær, Michael, Magnusson, Stig Peter & Hansen, P., 2021, In: Acta Radiologica. 62, 2, p. 215-224 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    USP7 is a SUMO deubiquitinase essential for DNA replication

    Lecona, E., Rodriguez-Acebes, S., Specks, J., Lopez-Contreras, Andres, Ruppen, I., Murga, M., Muñoz, J., Mendez, J. & Fernandez-Capetillo, O., 23 Apr 2016, In: Nature Structural and Molecular Biology. 23, 4, p. 270-277 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    UBL5 is essential for pre-mRNA splicing and sister chromatid cohesion in human cells

    Oka, Y., Varmark, H., Vitting-Seerup, K., Beli, P., Waage, J. E., Hakobyan, A., Mistrik, M., Choudhary, Chunaram, Rohde, M., Bekker-Jensen, Simon Holst & Mailand, Niels, 2014, In: E M B O Reports. 15, 9, p. 956-964 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Type VI collagen turnover-related peptides—novel serological biomarkers of muscle mass and anabolic response to loading in young men

    Nedergaard, A., Sun, S., Karsdal, M. A., Henriksen, K. S., Kjær, Michael, Lou, Y., He, Y., Zheng, Q. & Suetta, Charlotte, 2013, In: Journal of Cachexia, Sarcopenia and Muscle. 4, 4, p. 267-275 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Two integrated and highly predictive functional analysis-based procedures for the classification of MSH6 variants in Lynch syndrome

    Drost, M., Tiersma, Y., Glubb, D., Kathe, S., van Hees, S., Calléja, F., Zonneveld, J. B. M., Boucher, K. M., Ramlal, R. P. E., Thompson, B. A., Rasmussen, Lene Juel, Greenblatt, M. S., Lee, A., Spurdle, A. B., Tavtigian, S. V. & de Wind, N., 2020, In: Genetics in Medicine. 22, p. 847–856

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Tus-Ter as a tool to study site-specific DNA replication perturbation in eukaryotes

    Larsen, N. B., Hickson, Ian David & Mankouri, H. W., 1 Oct 2014, In: Cell Cycle. 13, 19, p. 2994-8 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Tumour predisposition and cancer syndromes as models to study gene–environment interactions

    Carbone, M., Arron, S. T., Beutler, B., Bononi, A., Cavenee, W., Cleaver, J. E., Croce, C. M., D’Andrea, A., Foulkes, W. D., Gaudino, G., Groden, J. L., Henske, E. P., Hickson, I. D., Hwang, P. M., Kolodner, R. D., Mak, T. W., Malkin, D., Monnat, R. J., Novelli, F., Pass, H. I. & 3 others, Petrini, J. H., Schmidt, L. S. & Yang, H., 2020, In: Nature Reviews Cancer. 20, p. 533–549

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Tomatidine enhances lifespan and healthspan in C. elegans through mitophagy induction via the SKN-1/Nrf2 pathway

    Fang, E. F., Waltz, T. B., Kassahun, H., Lu, Q., Kerr, J. S., Morevati, M., Fivenson, E. M., Wollman, B. N., Marosi, K., Wilson, M. A., Iser, W. B., Eckley, D. M., Zhang, Y., Lehrmann, E., Goldberg, I. G., Scheibye-Knudsen, Morten, Mattson, M. P., Nilsen, H., Bohr, Vilhelm & Becker, K. G., 2017, In: Scientific Reports. 7, 46208.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Thymidine kinase 1 deficient cells show increased survival rate after UV-induced DNA damage

    Skovgaard, T., Rasmussen, Lene Juel & Munch-Petersen, B., 2010, In: Nucleosides, Nucleotides and Nucleic Acids. 29, 4-6, p. 347-51 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    The ubiquitin- and SUMO-dependent signaling response to DNA double-strand breaks

    Bekker-Jensen, Simon Holst & Mailand, Niels, 12 Jun 2011, In: FEBS Letters. 585, p. 2914-2919 6 p.

    Research output: Contribution to journalReviewResearchpeer-review

  29. Published

    The single-biopsy approach in determining protein synthesis in human slow-turning-over tissue: use of flood-primed, continuous infusion of amino acid tracer

    Holm, L., Reitelseder, S., Dideriksen, K., Nielsen, R. H., Bülow, J. & Kjær, Michael, 23 Apr 2014, In: American Journal of Physiology: Endocrinology and Metabolism. 306, 11, p. E1330-39 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    The secrets of matrix mechanical loading

    Kjær, Michael, 2009, In: Scandinavian Journal of Medicine & Science in Sports. 19, 4, p. 455-456 1 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    The role of mitochondrial dysfunction in the progression of Alzheimer’s disease

    Desler, Claus, Lillenes, M. S., Tønjum, T. & Rasmussen, Lene Juel, 2018, In: Current Medicinal Chemistry. 25, 40, p. 5578 - 5587

    Research output: Contribution to journalReviewResearchpeer-review

  32. Published

    The role of RecQ helicases in non-homologous end-joining

    Keijzers, G., Maynard, S., Shamanna, R. A., Rasmussen, Lene Juel, Croteau, D. L. & Bohr, Vilhelm, Nov 2014, In: Critical Reviews in Biochemistry and Molecular Biology. 49, 6, p. 463-472 10 p.

    Research output: Contribution to journalReviewResearchpeer-review

  33. Published

    The response of mammalian cells to UV-light reveals Rad54-dependent and independent pathways of homologous recombination

    Eppink, B., Tafel, A. A., Hanada, K., van Drunen, E., Hickson, Ian David, Essers, J. & Kanaar, R., Nov 2011, In: D N A Repair. 10, 11, p. 1095-105 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    The regional turnover of cartilage collagen matrix in late-stage human knee osteoarthritis

    Jørgensen, A. E. M., Agergaard, J., Schjerling, Peter, Heinemeier, K. M., van Hall, Gerrit & Kjær, Michael, 2022, In: Osteoarthritis and Cartilage. 30, 6, p. 886-895

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    The proteomic profile of the human myotendinous junction

    Karlsen, Anders, Gonzalez-Franquesa, A., Jakobsen, J. R., Krogsgaard, Michael R., Koch, M., Kjær, Michael, Schiaffino, S., Mackey, Abigail & Deshmukh, Atul Shahaji, 2022, In: iScience. 25, 2, 19 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    The prevention and resolution of DNA replication–transcription conflicts in eukaryotic cells

    Wu, Wei, Hickson, Ian David & Liu, Ying, 2020, In: Genome Instability & Disease. 1, 3, p. 114–128 15 p.

    Research output: Contribution to journalReviewResearchpeer-review

  37. Published

    The pathogenesis of tendinopathy: balancing the response to loading

    Magnusson, Stig Peter, Langberg, Henning & Kjær, Michael, 2010, In: Nature Reviews Rheumatology. 6, 5, p. 262-8 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    The origins and processing of ultra fine anaphase DNA bridges

    Liu, Ying, Nielsen, Christian Friberg, Yao, Q. & Hickson, Ian David, 30 Apr 2014, In: Current Opinion in Genetics & Development. 26C, p. 1-5 5 p.

    Research output: Contribution to journalReviewResearchpeer-review

  39. Published

    The many lives of type IA topoisomerases

    Bizard, A. H. & Hickson, Ian David, 2020, In: Journal of Biological Chemistry. 295, 20, p. 7138-7153 16 p.

    Research output: Contribution to journalReviewResearchpeer-review

  40. Published

    The lactate receptor, G-protein-coupled receptor 81/hydroxycarboxylic acid receptor 1: Expression and action in brain

    Morland, C., Lauritzen, K. H., Puchades, M., Holm-Hansen, S., Andersson, K., Gjedde, Albert, Attramadal, H., Storm-Mathisen, J. & Bergersen, L. H., Jul 2015, In: Journal of Neuroscience Research. 93, 7, p. 1045-1055 11 p.

    Research output: Contribution to journalReviewResearchpeer-review

  41. Published

    The lactate receptor HCAR1 promotes neuronal development and protects axons and myelin during hypoglycemia

    Kennedy, L. H., Andersson, K. A., Haugen, O. P., Puchades, M. A., Storm-Mathisen, J., Morland, C., Bergersen, L. H. & Rinholm, J. E., Jun 2017, In: Glia. 65, S1, p. E152-E153 T03-024B.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  42. Published

    The inhibitors of soluble adenylate cyclase 2-OHE, KH7, and bithionol compromise mitochondrial ATP production by distinct mechanisms

    Jakobsen, Emil, Lange, S. C., Andersen, Jens Velde, Desler, Claus, Kihl, H. F., Hohnholt, M., Stridh, M. H., Rasmussen, Lene Juel, Waagepetersen, Helle S. & Bak, Lasse Kristoffer, 2018, In: Biochemical Pharmacology. 155, p. 92-101 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    The influence of training status on the drop in muscle strength after acute exercise

    Pingel, Jessica, Moerch, L., Kjær, Michael & Langberg, Henning, 2009, In: Journal of Applied Physiology. 106, 4, p. 605-11 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    The influence of prolonged strength training upon muscle and fat in healthy and chronically diseased older adults

    Gylling, A. T., Eriksen, C. S., Garde, Ellen, Wimmelmann, Cathrine Lawaetz, Reislev, N. L., Bieler, T., Ziegler, A. K., Andersen, K. W., Bauer, C., Dideriksen, K., Bækgaard, M., Mertz, K. H., Bayer, M. L., Bloch-Ibenfeldt, M., Boraxbekk, CJ, Siebner, Hartwig Roman, Mortensen, Erik Lykke & Kjær, Michael, 2020, In: Experimental Gerontology. 136, 110939.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    The influence of fibrillin‐1 and physical activity upon tendon tissue morphology and mechanical properties in mice

    Tran, P. H. T., Skrba, T., Wondimu, E., Galatioto, G., Svensson, R. B., Olesen, A. T., Mackey, Abigail, Magnusson, Stig Peter, Ramirez, F. & Kjær, Michael, 1 Nov 2019, In: Physiological Reports. 7, 21, 9 p., e14267 .

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    The influence of direct and indirect fibroblast cell contact on human myogenic cell behaviour and gene expression in vitro

    Bechshøft, C. J. L., Schjerling, Peter, Kjær, Michael & Mackey, Abigail, 2019, In: Journal of Applied Physiology. 127, 2, p. 342-355

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    The importance of mitochondrial DNA in aging and cancer

    Desler, Claus, Espersen, M. L. M., Singh, K. K. & Rasmussen, Lene Juel, 30 Mar 2011, In: Journal of Aging Research. 2011, p. 407536

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    The human myotendinous junction: An ultrastructural and 3D analysis study

    Knudsen, A. B., Larsen, M., Mackey, Abigail, Hjort, M., Hansen, K. K., Qvortrup, Klaus, Kjær, Michael & Krogsgaard, Michael R., Feb 2015, In: Scandinavian Journal of Medicine & Science in Sports. 25, 1, p. E116-23

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    The helicase and ATPase activities of RECQL4 are compromised by mutations reported in three human patients

    Jensen, M. B., Dunn, C. A., Keijzers, G., Kulikowicz, T., Rasmussen, Lene Juel, Croteau, D. L. & Bohr, Vilhelm, Nov 2012, In: Aging. 4, 11, p. 790-802 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    The heat shock protein response following eccentric exercise in human skeletal muscle is unaffected by local NSAID infusion

    Mikkelsen, U. R., Paulsen, G., Schjerling, Peter, Helmark, I. C., Langberg, Henning, Kjær, Michael & Heinemeier, K. M., 2013, In: European Journal of Applied Physiology. 113, 7, p. 1883-1893 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  51. Published

    The hallmarks of aging

    Gilmour, B. C., Bergersen, L. H. & Fang, E. F., 2022, Molecular, Cellular, and Metabolic Fundamentals of Human Aging. Academic Press, p. 1-6 6 p.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  52. Published

    The effect of strength training, recreational soccer and running exercise on stretch-shortening cycle muscle performance during countermovement jumping

    Jakobsen, M. D., Sundstrup, E., Randers, M. B., Kjær, Michael, Andersen, L. L., Krustrup, P. & Aagaard, P., 2012, In: Human Movement Science. 31, 4, p. 970-986 17 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  53. Published

    The effect of resistance exercise upon age-related systemic and local skeletal muscle inflammation

    Ziegler, A. K., Jensen, S. M., Schjerling, P., Mackey, Abigail, Andersen, J. L. & Kjær, Michael, 2019, In: Experimental Gerontology. 121, p. 19-32

    Research output: Contribution to journalJournal articleResearchpeer-review

  54. Published

    The effect of mitochondrial dysfunction on cytosolic nucleotide metabolism

    Desler, Claus, Lykke, A. & Rasmussen, Lene Juel, 1 Jan 2010, In: Journal of Nucleic Acids. 2010

    Research output: Contribution to journalJournal articleResearchpeer-review

  55. Published

    The effect of acute exercise on collagen turnover in human tendons: influence of prior immobilization period

    Mørch, L. S., Pingel, Jessica, Boesen, M., Kjær, Michael & Langberg, Henning, 2013, In: European Journal of Applied Physiology. 113, 2, p. 449-455 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  56. Published

    The effect of 4 months exercise training on systemic biomarkers of cartilage and bone turnover in hip osteoarthritis patients

    Ellegaard, M., Bieler, T., Beyer, N., Kjær, Michael & Jørgensen, Niklas Rye, 2020, In: Translational Sports Medicine. 3, 1, p. 16-25

    Research output: Contribution to journalJournal articleResearchpeer-review

  57. Published

    The deubiquitylating enzyme USP44 counteracts the DNA double-strand break response mediated by the RNF8 and RNF168 ubiquitin ligases

    Mosbech, A., Lukas, Claudia, Bekker-Jensen, Simon Holst & Mailand, Niels, 24 Apr 2013, In: Journal of Biological Chemistry. 288, p. 16579-16587 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  58. Published

    The changing brain--insights into the mechanisms of neural and behavioral adaptation to the environment

    Bergersen, L. H., Bramham, C. R., Hugdahl, K., Sander, M. & Storm-Mathisen, J., 5 Sep 2013, In: Neuroscience. 247, p. 412-22 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  59. Published

    The challenges of human population ageing

    Sander, M., Oxlund, Bjarke, Jespersen, Astrid Pernille, Krasnik, Allan, Mortensen, Erik Lykke, Westendorp, Rudi GJ & Rasmussen, Lene Juel, Mar 2015, In: Age and Ageing. 44, 2, p. 185-7 3 p.

    Research output: Contribution to journalJournal articleCommunication

  60. Published

    The breaking and making of healthy adult human skeletal muscle in vivo

    Mackey, Abigail & Kjær, Michael, 2017, In: Skeletal Muscle. 7, 18 p., 24.

    Research output: Contribution to journalJournal articleResearchpeer-review

  61. Published

    The battle to keep or lose skeletal muscle with ageing

    Kjær, Michael & Jespersen, J. G., 2009, In: Journal of Physiology. 587, Pt 1, p. 1-2 2 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  62. Published

    The anabolis potential of dietary protein intake on skeletal muscle is prolonged by prior light-load exercise

    Bechshøft, R., Dideriksen, K. J., Reitelseder, S., Scheike, Thomas, Kjær, Michael & Holm, L., 2013, In: Clinical Nutrition. 32, 2, p. 236-244

    Research output: Contribution to journalJournal articleResearchpeer-review

  63. Published

    The ZGRF1 Helicase Promotes Recombinational Repair of Replication-Blocking DNA Damage in Human Cells

    Brannvoll, A., Xue, X., Kwon, Y., Kompocholi, Smaragda, Simonsen, Anne Katrine Wrist, Bagge, Keerthana Stine Viswalingam, Gonzalez, L., Hickson, Ian David, Østergaard, Vibe Hallundbæk, Mankouri, H. W., Sung, P. & Lisby, Michael, 2020, In: Cell Reports. 32, 1, 25 p., 107849.

    Research output: Contribution to journalJournal articleResearchpeer-review

  64. Published

    The Ubiquitin Ligase XIAP Recruits LUBAC for NOD2 Signaling in Inflammation and Innate Immunity

    Damgaard, R. B., Nachbur, U., Yabal, M., Wong, W. W., Fiil, Berthe Katrine, Kastirr, M., Rieser, E., Rickard, J. A., Bankovacki, A., Peschel, C., Ruland, J., Bekker-Jensen, Simon Holst, Mailand, Niels, Kaufmann, T., Strasser, A., Walczak, H., Silke, J., Jost, P. J. & Gyrd-Hansen, Mads, 2012, In: Molecular Cell. 46, 6, p. 746-58 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  65. Published

    The Ruptured Achilles Tendon Elongates for 6 Months After Surgical Repair Regardless of Early or Late Weightbearing in Combination With Ankle Mobilization: A Randomized Clinical Trial

    Eliasson, P., Agergaard, A., Couppe, C., Svensson, R., Hoeffner, R., Warming, S., Warming, N., Holm, C., Jensen, M. H., Krogsgaard, Michael R., Kjær, Michael & Magnusson, Stig Peter, 2018, In: American Journal of Sports Medicine. 46, 10, p. 2492-2502

    Research output: Contribution to journalJournal articleResearchpeer-review

  66. Published

    The NAD+-mitophagy axis in healthy longevity and in artificial intelligence-based clinical applications

    Aman, Y., Frank, J., Lautrup, S. H., Matysek, A., Niu, Z., Yang, G., Shi, L., Bergersen, L. H., Storm-Mathisen, J., Rasmussen, Lene Juel, Bohr, Vilhelm, Nilsen, H. & Fang, E. F., 2020, In: Mechanisms of Ageing and Development. 185, 111194.

    Research output: Contribution to journalJournal articleResearchpeer-review

  67. Published

    The Journal of Cerebral Blood Flow and Metabolism clinical, inaugural issue

    Lauritzen, Martin & Dirnagl, U., Jan 2016, In: Journal of Cerebral Blood Flow and Metabolism. 36, 1, p. 3-3

    Research output: Contribution to journalEditorialResearch

  68. Published

    The Escherichia coli Tus-Ter replication fork barrier causes site-specific DNA replication perturbation in yeast

    Larsen, N. B., Sass, E., Suski, C., Mankouri, H. W. & Hickson, Ian David, 2014, In: Nature Communications. 5, p. 1-10 10 p., 3574.

    Research output: Contribution to journalJournal articleResearchpeer-review

  69. Published

    The Effect of Aging and Mechanical Loading on the Metabolism of Articular Cartilage

    Jørgensen, A. E. M., Kjær, Michael & Heinemeier, K. M., Apr 2017, In: Journal of Rheumatology. 44, 4, p. 410-417

    Research output: Contribution to journalReviewResearchpeer-review

  70. Published

    The Dissolution of Double Holliday Junctions

    Bizard, A. H. & Hickson, Ian David, 1 Jul 2014, In: Cold Spring Harbor perspectives in biology. 6, p. 1-16 16 p., a016477.

    Research output: Contribution to journalReviewResearchpeer-review

  71. Published

    The Detection and Analysis of Chromosome Fragile Sites

    Bjerregaard, Victoria Alexandra, Özer, Ö., Hickson, Ian David & Liu, Ying, 2018, Genome Instability: Methods and Protocols. Springer, Vol. 1672. p. 471-482 12 p. (Methods in molecular biology (Clifton, N.J.)).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  72. Published

    The "enemies within": regions of the genome that are inherently difficult to replicate

    Bhowmick, Rahul & Hickson, Ian David, 2017, In: F1000Research. 6, 7 p., 666.

    Research output: Contribution to journalReviewResearchpeer-review

  73. Published

    Tensile force transmission in human patellar tendon fascicles is not mediated by glycosaminoglycans

    Svensson, R. B., Hassenkam, Tue, Hansen, P., Kjær, Michael & Magnusson, Stig Peter, 2011, In: Connective Tissue Research. 52, 5, p. 415-21 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  74. Published

    Tendon protein synthesis rate in classic Ehlers-Danlos patients can be stimulated with insulin-like growth factor-I

    Nielsen, R. H., Holm, L., Jensen, J. K., Heinemeier, K. M., Remvig, L. & Kjær, Michael, 1 Oct 2014, In: Journal of Applied Physiology. 117, 7, p. 694-698 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  75. Published

    Tendon properties in a mouse model of severe osteogenesis imperfecta

    Sinkam, L., Boraschi-Diaz, I., Svensson, R. B., Kjær, Michael, Komarova, S. V., Bergeron, R., Rauch, F. & Veilleux, L. N., 2023, In: Connective Tissue Research. 64, 3, p. 285-293

    Research output: Contribution to journalJournal articleResearchpeer-review

  76. Published

    Tendon collagen synthesis declines with immobilization in elderly humans: no effect of anti-inflammatory medication

    Dideriksen, K., Boesen, A. P., Reitelseder, S., Couppé, C., Svensson, R., Schjerling, P., Magnusson, Stig Peter, Holm, L. & Kjær, Michael, Feb 2017, In: Journal of Applied Physiology. 122, 2, p. 273-282 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  77. Published

    Tendon blood flow, angiogenesis, and tendinopathy pathogenesis

    Merkel, M. F. R., Hellsten, Ylva, Magnusson, Stig Peter & Kjær, Michael, 2021, In: Translational Sports Medicine. 4, 6, p. 756-771 16 p.

    Research output: Contribution to journalReviewResearchpeer-review

  78. Published

    Tendon and skeletal muscle matrix gene expression and functional responses to immobilisation and rehabilitation in young males: Effect of growth hormone administration

    Boesen, A. P., Dideriksen, K., Couppé, Christian, Magnusson, P., Schjerling, Peter, Boesen, M., Kjær, Michael & Langberg, Henning, 30 Sep 2013, In: Journal of Physiology. p. 6039-6052

    Research output: Contribution to journalJournal articleResearchpeer-review

  79. Published

    TRIP12 and UBR5 Suppress Spreading of Chromatin Ubiquitylation at Damaged Chromosomes

    Gudjónsson, Thorkell, Altmeyer, M. F., Savic, V., Toledo Lazaro, L. I., Dinant, C., Grøfte, M., Bartkova, J., Poulsen, M., Oka, Y., Bekker-Jensen, Simon Holst, Mailand, Niels, Neumann, B., Heriche, J., Shearer, R., Saunders, D., Bartek, J., Lukas, Jiri & Lukas, Claudia, 17 Aug 2012, In: Cell. 150, 4, p. 697-709 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  80. Published

    TRAIP is a PCNA-binding ubiquitin ligase that protects genome stability after replication stress

    Hoffmann, Saskia, Smedegaard, S., Nakamura, K., Mortuza, G. B., Räschle, M., Ibañez de Opakua, A., Oka, Y., Feng, Y., Blanco, F. J., Mann, Matthias, Montoya, Guillermo, Groth, Anja, Bekker-Jensen, Simon Holst & Mailand, Niels, 4 Jan 2016, In: The Journal of Cell Biology. 212, 1, p. 63-75

    Research output: Contribution to journalJournal articleResearchpeer-review

  81. Published

    TIP60 in aging and neurodegeneration

    Li, Zhiquan & Rasmussen, Lene Juel, 2020, In: Ageing Research Reviews. 64, 101195.

    Research output: Contribution to journalReviewResearchpeer-review

  82. Published

    THE EXTRACELLULAR MATRIX AND ITS ADAPTATIONS TO CHANGE IN CHRONIC LOADING

    Kjær, Michael, Magnusson, P., Suetta, Charlotte, Dossing, S., Heinemeier, K., Schjerling, Peter, Hansen, M., Kongsgaard, M., Mackey, Abigail, Andersen, J. L. & Langberg, Henning, 2009, p. 62-62.

    Research output: Contribution to conferenceConference abstract for conferenceResearchpeer-review

  83. Published

    Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass

    Povlsen, L. K., Beli, P., Wagner, S. A., Poulsen, S. L., Sylvestersen, K. B., Poulsen, J. W., Nielsen, Michael Lund, Bekker-Jensen, Simon Holst, Mailand, Niels & Choudhary, Chunaram, Oct 2012, In: Nature Cell Biology. 14, 10, p. 1089-98 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  84. Published

    Systems modelling predicts chronic inflammation and genomic instability prevent effective mitochondrial regulation during biological ageing

    Guimera, A. M., Clark, P., Wordsworth, J., Anugula, Sharath, Rasmussen, Lene Juel & Shanley, D. P., 2022, In: Experimental Gerontology. 166, 9 p., 111889.

    Research output: Contribution to journalReviewResearchpeer-review

  85. Published

    Synthesis and SAR studies of 5-(pyridin-4-yl)-1,3,4-thiadiazol-2-amine derivatives as potent inhibitors of Bloom helicase

    Rosenthal, A. S., Dexheimer, T. S., Gileadi, O., Nguyen, G. H., Chu, W. K., Hickson, Ian David, Jadhav, A., Simeonov, A. & Maloney, D. J., 15 Oct 2013, In: Bioorganic & Medicinal Chemistry Letters. 23, 20, p. 5660-6 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  86. Published

    Supraphysiological protection from replication stress does not extend mammalian lifespan

    Albers, E., Avram, Alexandra Ioana, Sbroggio, M., Fernandez-Capetillo, O. & Lopez-Contreras, Andres, 2020, In: Aging. 12, 7, p. 5612-5624 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  87. Published

    Subjective sleep quality and daytime sleepiness in late midlife and their association with age-related changes in cognition

    Waller, K. L., Mortensen, Erik Lykke, Avlund, K., Osler, Merete, Fagerlund, Birgitte, Lauritzen, Martin & Jennum, Poul, Jan 2016, In: Sleep Medicine. 17, p. 165-73 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  88. Published

    Subclinical cognitive decline in middle-age is associated with reduced task-induced deactivation of the brain's default mode network

    Hansen, N. L., Lauritzen, Martin, Mortensen, Erik Lykke, Osler, Merete, Avlund, K., Fagerlund, Birgitte & Rostrup, E., Sep 2014, In: Human Brain Mapping. 35, 9, p. 4488-98 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  89. Published

    Sub-Clinical Cognitive Decline and Resting Cerebral Blood Flow in Middle Aged Men

    Henriksen, O. M., Hansen, N. L., Osler, Merete, Mortensen, Erik Lykke, Hallam, D. M., Pedersen, E. T., Chappell, M., Lauritzen, Martin & Rostrup, E., 2017, In: PLOS ONE. 12, 1, 15 p., e0169912.

    Research output: Contribution to journalJournal articleResearchpeer-review

  90. Published

    Structure-specific endonucleases: guardians of fragile site stability

    Minocherhomji, S. & Hickson, Ian David, May 2014, In: Trends in Cell Biology. 24, 5, p. 321-327 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  91. Published

    Structural, biochemical, cellular, and functional changes in skeletal muscle extracellular matrix with aging

    Kragstrup, T. W., Kjær, Michael & Mackey, Abigail, 2011, In: Scandinavian Journal of Medicine & Science in Sports. 21, 6, p. 749-57 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  92. Published

    Structural and mechanistic insight into Holliday-junction dissolution by topoisomerase IIIα and RMI1

    Bocquet, N., Bizard, A. H., Abdulrahman, W., Larsen, N. B., Faty, M., Cavadini, S., Bunker, R. D., Kowalczykowski, S. C., Cejka, P., Hickson, Ian David & Thomä, N. H., Mar 2014, In: Nature Structural and Molecular Biology. 21, 3, p. 261-8 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  93. Published

    Structural And Physiological Changes In Chronically overused Achilles tendons

    Langberg, Henning, Pingel, Jessica, Fredberg, U., Qvortrup, Klaus, Overgaard, J. & Kjær, Michael, May 2012, In: Medicine and Science in Sports and Exercise. 44, p. 116 1 p.

    Research output: Contribution to journalConference articleResearchpeer-review

  94. Published

    Structural Analysis of a Complex between Small Ubiquitin-like Modifier 1 (SUMO1) and the ZZ Domain of CREB-binding Protein (CBP/p300) Reveals a New Interaction Surface on SUMO

    Diehl, C., Akke, M., Bekker-Jensen, Simon Holst, Mailand, Niels, Streicher, W. & Wikström, M., 10 Jun 2016, In: Journal of Biological Chemistry. 291, 24, p. 12658-12672 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  95. Published

    Stimulation-induced increases in cerebral blood flow and local capillary vasoconstriction depend on conducted vascular responses

    Cai, Changsi, Fordsmann, J. C., Jensen, S. H., Gesslein, B., wbh615, wbh615, Hald, B. O., Zambach, S. A., Larsen, Birger Brodin & Lauritzen, Martin, 2018, In: Proceedings of the National Academy of Sciences of the United States of America. 115, 25, p. E5796-E5804 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  96. Published

    Stalled replication forks generate a distinct mutational signature in yeast

    Larsen, N. B., Liberti, S. E., Vogel, Ivan, Jorgensen, S. W., Hickson, Ian David & Mankouri, H. W., 2017, In: Proceedings of the National Academy of Sciences of the United States of America. 114, 36, p. 9665-9670

    Research output: Contribution to journalJournal articleResearchpeer-review

  97. Published

    Spreading Depression, Spreading Depolarizations, and the Cerebral Vasculature

    Ayata, C. & Lauritzen, Martin, Jul 2015, In: Physiological Reviews. 95, 3, p. 953-993 41 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  98. Published

    Spontaneous calcium waves in Bergman glia increase with age and hypoxia and may reduce tissue oxygen

    Mathiesen, C., Brazhe, A., Thomsen, Kirsten Joan & Lauritzen, Martin, 2013, In: Journal of Cerebral Blood Flow and Metabolism. 33, p. 161-9 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  99. Published

    Spontaneous astrocytic Ca2+ activity abounds in electrically suppressed ischemic penumbra of aged mice

    Fordsmann, J. C., Murmu, R. P., Cai, Changsi, Brazhe, A., Thomsen, Kirsten Joan, Zambach, S. A., wbh615, wbh615, Lind, Barbara Lykke & Lauritzen, Martin, 2019, In: Glia. 67, 1, p. 37-52 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  100. Published

    Spinal dorsal horn astrocytes release GABA in response to synaptic activation

    Christensen, R. K., Delgado-Lezama, R., Russo, R. E., Lind, Barbara Lykke, Alcocer, E. L., Rath, Martin Fredensborg, Fabbiani, G., Schmitt, Nicole, Lauritzen, Martin, Petersen, A. V., Carlsen, Eva Maria Meier & Perrier, Jean-Francois Marie, 2018, In: The Journal of Physiology. 596, 20, p. 4983-4994 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

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