Damage and Repair

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  1. Published

    'Spreading depression of Leão' and its emerging relevance to acute brain injury in humans

    Lauritzen, Martin & Strong, A. J., 2016, In: Journal of Cerebral Blood Flow and Metabolism. 37, 5, p. 1553-1570

    Research output: Contribution to journal › Review › Research › peer-review

  2. Published

    14-3-3 checkpoint regulatory proteins interact specifically with DNA repair protein human exonuclease 1 (hEXO1) via a semi-conserved motif

    Andersen, S. D., Keijzers, G., Rampakakis, E., Engels, K., Luhn, P., El-Shemerly, M., Nielsen, Finn Cilius, Du, Y., May, A., Bohr, Vilhelm, Ferrari, S., Zannis-Hadjopoulos, M., Fu, H. & Rasmussen, Lene Juel, Mar 2012, In: D N A Repair. 11, 3, p. 267-77 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    18F-fluorodeoxyglucose and PET/CT for noninvasive study of exercise-induced glucose uptake in rat skeletal muscle and tendon

    Skovgaard, D., Kjær, Michael, El Ali, Henrik H. & Kjær, Andreas, May 2009, In: European Journal of Nuclear Medicine and Molecular Imaging. 36, 5, p. 859-68 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    3-D ultrastructure and collagen composition of healthy and overloaded human tendon: evidence of tenocyte and matrix buckling

    Pingel, Jessica, Lu, Y., Starborg, T., Fredberg, U., Langberg, Henning, Nedergaard, A., Weis, M., Eyre, D., Kjær, Michael & Kadler, K. E., 9 Feb 2014, In: Journal of Anatomy. 224, 5, p. 548–555 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    3-Hydroxybutyrate regulates energy metabolism and induces BDNF expression in cerebral cortical neurons

    Marosi, K., Kim, S. W., Moehl, K., Scheibye-Knudsen, Morten, Cheng, A., Cutler, R., Camandola, S. & Mattson, M. P., Dec 2016, In: Journal of Neurochemistry. 139, 5, p. 769-781 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    53BP1 nuclear bodies form around DNA lesions generated by mitotic transmission of chromosomes under replication stress

    Lukas, Claudia, Savic, V., Bekker-Jensen, Simon Holst, Doil, C., Neumann, B., Pedersen, R. S., Grøfte, M., Chan, K. L., Hickson, Ian David, Bartek, J. & Lukas, Jiri, 1 Mar 2011, In: Nature Cell Biology. 13, 3, p. 243-53 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Helicobacter pylori infection affects mitochondrial function and DNA repair, thus, mediating genetic instability in gastric cells

    Machado, A. M. D., Desler, C., Boggild, S., Strickertsson, J. A. B., Friis-Hansen, Lennart Jan, Figueiredo, C., Seruca, R. & Rasmussen, Lene Juel, 2013, In: Mechanisms of Ageing and Development. 134, 10, p. 460-466 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Rev1 deficiency induces a metabolic shift in MEFs that can be manipulated by the NAD+ precursor nicotinamide riboside

    Anugula, Sharath, Li, Zhiquan, Li, Yuan, Hendriksen, A., Christensen, P. B., Wang, L., Monk, J. M., de Wind, N., Bohr, Vilhelm, Desler, Claus, Naviaux, R. K. & Rasmussen, Lene Juel, 2023, In: Heliyon. 9, 6, e17392.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    A Ketogenic Diet Improves Mitochondrial Biogenesis and Bioenergetics via the PGC1α-SIRT3-UCP2 Axis

    Hasan-Olive, M. M., Lauritzen, K. H., Ali, M., Rasmussen, Lene Juel, Storm-Mathisen, J. & Bergersen, L. H., 2019, In: Neurochemical Research. 44, 1, p. 22-37 16 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    A Molecular Toolbox to Engineer Site-Specific DNA Replication Perturbation

    Larsen, N. B., Hickson, Ian David & Mankouri, H. W., 2018, Genome Instability: Methods and Protocols. Springer, Vol. 1672. p. 295-309 15 p. (Methods in molecular biology (Clifton, N.J.)).

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  11. Published

    A Novel Rrm3 Function in Restricting DNA Replication via an Orc5-Binding Domain Is Genetically Separable from Rrm3 Function as an ATPase/Helicase in Facilitating Fork Progression

    Syed, S., Desler, Claus, Rasmussen, Lene Juel & Schmidt, K. H., Dec 2016, In: P L o S Genetics. 12, 12, 28 p., e1006451.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Published

    A Role for BLM in Double-Strand Break Repair Pathway Choice: Prevention of CtIP/Mre11-Mediated Alternative Nonhomologous End-Joining.

    Grabarz, A., Guirouilh-Barbat, J., Barascu, A., Pennarun, G., Genet, D., Rass, E., Germann, S. M., Bertrand, P., Hickson, Ian David & Lopez, B. S., 17 Oct 2013, In: Cell Reports. 5, 1, p. 21-28 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    A Single Conserved Residue Mediates Binding of the Ribonucleotide Reductase Catalytic Subunit RRM1 to RRM2 and Is Essential for Mouse Development

    Specks, J., Lecona, E., Lopez-Contreras, Andres & Fernandez-Capetillo, O., Sep 2015, In: Molecular and Cellular Biology. 35, 17, p. 2910-2917 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    A Small Molecule Inhibitor of the BLM Helicase Modulates Chromosome Stability in Human Cells

    Nguyen, G. H., Dexheimer, T. S., Rosenthal, A. S., Chu, W. K., Singh, D. K., Mosedale, G., Bachrati, C. Z., Schultz, L., Sakurai, M., Savitsky, P., Abu, M., McHugh, P. J., Bohr, Vilhelm, Harris, C. C., Jadhav, A., Gileadi, O., Maloney, D. J., Simeonov, A. & Hickson, Ian David, 24 Jan 2013, In: Chemistry & Biology. 20, 1, p. 55-62 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    A critical role for astrocytes in hypercapnic vasodilation in brain

    Howarth, C., Sutherland, B. A., Choi, H. B., Martin, C., Lind, Barbara Lykke, Khennouf, Lila, LeDue, J. M., Pakan, J. M. P., Ko, R. W., Ellis-Davies, G. C. R., Lauritzen, Martin, Sibson, N. R., Buchan, A. M. & MacVicar, B. A., 2017, In: The Journal of Neuroscience. 37, 9, p. 2403-2414 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    A cross-sectional study of functional and metabolic changes during aging through the lifespan in male mice

    Petr, Michael Angelo, Alfaras, I., Krawcyzk, M., Bair, W. N., Mitchell, S. J., Morrell, C. H., Studenski, S. A., Price, N. L., Fishbein, K. W., Spencer, R. G., Scheibye-Knudsen, Morten, Lakatta, E. G., Ferrucci, L., Aon, M. A., Bernier, M. & de Cabo, R., 2021, In: eLife. 10, 25 p., e62952.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    A defined human aging phenome

    Andreassen, Søren Norge, Ben Ezra, Michael & Scheibye-Knudsen, Morten, 2019, In: Aging. 11, 15, p. 5786-5806 21 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    A functional assay–based procedure to classify mismatch repair gene variants in Lynch syndrome

    Drost, M., Tiersma, Y., Thompson, B. A., Frederiksen, J. H., Keijzers, G., Glubb, D., Kathe, S., Osinga, J., Westers, H., Pappas, L., Boucher, K. M., Molenkamp, S., Zonneveld, J. B., van Asperen, C. J., Goldgar, D. E., Wallace, S. S., Sijmons, R. H., Spurdle, A. B., Rasmussen, L. J., Greenblatt, M. S. & 2 others, de Wind, N. & Tavtigian, S. V., 2019, In: Genetics in Medicine. 21, p. 1486–1496

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    A high-fat diet and NAD+ activate sirt1 to rescue premature aging in cockayne syndrome

    Scheibye-Knudsen, M., Mitchell, S. J., Fang, E. F., Iyama, T., Ward, T., Wang, J., Dunn, C. A., Singh, N., Veith, S., Hasan-Olive, M. M., Mangerich, A., Wilson, M. A., Mattson, M. P., Bergersen, L. H., Cogger, V. C., Warren, A., Le Couteur, D. G., Moaddel, R., Wilson, D. M., Croteau, D. L. & 2 others, De Cabo, R. & Bohr, Vilhelm, 4 Nov 2014, In: Cell Metabolism. 20, 5, p. 840-855 16 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    A ketogenic diet accelerates neurodegeneration in mice with induced mitochondrial DNA toxicity in the forebrain

    Lauritzen, K. H., Hasan-Olive, M. M., Regnell, C. E., Kleppa, L., Scheibye-Knudsen, Morten, Gjedde, Albert, Klungland, A., Bohr, Vilhelm, Storm-Mathisen, J. & Bergersen, L. H., Dec 2016, In: Neurobiology of Aging. 48, p. 34-47

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    A new cellular stress response that triggers centriolar satellite reorganization and ciliogenesis

    Villumsen, B. H., Danielsen, J. R., Povlsen, L., Sylvestersen, K. B., Merdes, A., Beli, P., Yang, Y., Choudhary, Chunaram, Nielsen, Michael Lund, Mailand, Niels & Bekker-Jensen, Simon Holst, 11 Oct 2013, In: E M B O Journal. 32, 23, p. 3029-3040

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    A new home for the Journal of Cerebral Blood Flow and Metabolism

    Dirnagl, U. & Lauritzen, Martin, Feb 2016, In: Journal of Cerebral Blood Flow and Metabolism. 36, 2, p. 277

    Research output: Contribution to journal › Editorial › Research › peer-review

  23. Published

    A new non-catalytic role for ubiquitin ligase RNF8 in unfolding higher-order chromatin structure

    Luijsterburg, M. S., Acs, K., Ackermann, L., Wiegant, W. W., Bekker-Jensen, Simon Holst, Larsen, D. H., Khanna, K. K., van Attikum, H., Mailand, Niels & Dantuma, N. P., 2012, In: E M B O Journal. 31, 11, p. 2511-27 17 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    A novel TPR-BEN domain interaction mediates PICH-BEND3 association

    Pitchai, G. P., Kaulich, M., Bizard, A. H., Mesa, Pablo, Yao, Q., Sarlos, K., Streicher, W. W., Nigg, E. A., Montoya, Guillermo & Hickson, Ian David, 2017, In: Nucleic Acids Research. 19, 2, p. 11413–11424

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    A novel antirecombinase gains PARIty

    Mankouri, H. W., Chu, W. K. & Hickson, Ian David, Jan 2012, In: Molecular Cell. 45, 1, p. 6-7 2 p.

    Research output: Contribution to journal › Review › Research › peer-review

  26. Published

    A novel method for determining human ex vivo submaximal skeletal muscle mitochondrial function

    Hey-Mogensen, M., Gram, M., Jensen, M. B., Lund, M. T., Hansen, C. N., Scheibye-Knudsen, Morten, Bohr, Vilhelm & Dela, Flemming, 1 Sep 2015, In: The Journal of Physiology. 593, 17, p. 3991-4010 20 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    A novel splice variant of Elp3/Kat9 regulates mitochondrial tRNA modification and function

    Boutoual, R., Jo, H., Heckenbach, Indra John, Tiwari, R., Kasler, H., Lerner, C. A., Shah, S., Schilling, B., Calvanese, V., Rardin, M. J., Scheibye-Knudsen, Morten & Verdin, E., 2022, In: Scientific Reports. 12, 14804.

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    A rapid and cell-free assay to test the activity of lynch syndrome-associated MSH2 and MSH6 missense variants

    Drost, M., Zonneveld, J. B. M., van Hees, S., Rasmussen, Lene Juel, Hofstra, R. M. W. & de Wind, N., 2012, In: Human Mutation. 33, 3, p. 488-94 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    A short G1 phase imposes constitutive replication stress and fork remodelling in mouse embryonic stem cells

    Ahuja, A. K., Jodkowska, K., Teloni, F., Bizard, A. H., Zellweger, R., Herrador, R., Ortega, S., Hickson, Ian David, Altmeyer, M., Mendez, J. & Lopes, M., Feb 2016, In: Nature Communications. 7, 11 p., 10660.

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    A simple DNA recombination screening method by RT-PCR as an alternative to Southern blot

    Albers, E., Sbroggiò, M., Martin Gonzalez, Javier, Avram, Alexandra Ioana, Munk, S. & Lopez-Contreras, Andres, Jun 2017, In: Transgenic Research. 26, 3, p. 429-434 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Published

    A small interfering RNA screen of genes involved in DNA repair identifies tumor-specific radiosensitization by POLQ knockdown

    Higgins, G. S., Prevo, R., Lee, Y., Helleday, T., Muschel, R. J., Taylor, S., Yoshimura, M., Hickson, Ian David, Bernhard, E. J. & McKenna, W. G., Apr 2010, In: Cancer Research. 70, 7, p. 2984-93 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. Published

    ARDD 2020: from aging mechanisms to interventions

    Mkrtchyan, G. V., Abdelmohsen, K., Andreux, P., Bagdonaite, I., Barzilai, N., Brunak, S., Cabreiro, F., Cabo, R. D., Campisi, J., Cuervo, A. M., Demaria, M., Ewald, C. Y., Fang, E. F., Faragher, R., Ferrucci, L., Freund, A., Silva-García, C. G., Georgievskaya, A., Gladyshev, V. N., Glass, D. J. & 46 others, Gorbunova, V., Grey, A. D., He, W. W., Hoeijmakers, J., Hoffmann, Eva, Horvath, S., Houtkooper, R. H., Jensen, Majken Karoline, Jensen, M. B., Kane, A., Kassem, Moustapha Saad El-Deen, Keizer, P. D., Kennedy, B., Karsenty, G., Lamming, D. W., Lee, K. F., MacAulay, Nanna, Mamoshina, P., Mellon, J., Molenaars, M., Moskalev, A., Mund, Andreas, Niedernhofer, L., Osborne, Brenna, Pak, H. H., Parkhitko, A., Raimundo, N., Rando, T. A., Rasmussen, Lene Juel, Reis, C., Riedel, C. G., Franco-Romero, A., Schumacher, B., Sinclair, D. A., Suh, Y., Taub, P. R., Toiber, D., Treebak, Jonas Thue, Valenzano, D. R., Verdin, E., Vijg, J., Young, S., Zhang, L., Bakula, Daniela Janina, Zhavoronkov, A. & Scheibye-Knudsen, Morten, 2020, In: Aging. 12, 24, p. 24486-24503 18 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. Published

    ATP induce an increase in intracellular Ca2+ in pericytes of the blood-brain barrier

    Jensen, S. H., Helms, H. C. C., Jessen, S. B., Lauritzen, Martin, Waagepetersen, Helle S. & Larsen, Birger Brodin, 2 Nov 2015.

    Research output: Contribution to conference › Poster › Research › peer-review

  34. Published

    ATP induce intracellular calcium rises in cultures of primary brain pericytes

    Jensen, S. H., Helms, H. C. C., Jessen, S. B., Lauritzen, Martin, Waagepetersen, Helle S. & Larsen, Birger Brodin, Jun 2016.

    Research output: Contribution to conference › Conference abstract for conference › Research › peer-review

  35. Published

    ATP induces contraction of cultured brain capillary pericytes, via activation of P2Y type purinergic receptors

    Hørlyck, S., Cai, Changsi, Helms, H. C., Lauritzen, Martin & Larsen, Birger Brodin, 2021, In: American Journal of Physiology: Heart and Circulatory Physiology. 320, p. H699–H712 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    ATR Prohibits Replication Catastrophe by Preventing Global Exhaustion of RPA

    Toledo Lazaro, L. I., Altmeyer, M., Rask, M., Lukas, Claudia, Larsen, D. H., Povlsen, L. K., Bekker-Jensen, Simon Holst, Mailand, Niels, Bartek, J. & Lukas, Jiri, 21 Nov 2013, In: Cell. 155, 5, p. 1088-1103 16 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Published

    ATR expands embryonic stem cell fate potential in response to replication stress

    Atashpaz, S., Samadi Shams, S., Martin Gonzalez, Javier, Sebestyén, E., Arghavanifard, N., Gnocchi, A., Albers, E., Minardi, S., Faga, G., Soffientini, P., Allievi, E., Cancila, V., Bachi, A., Fernández-Capetillo, Ó., Tripodo, C., Ferrari, F., Lopez-Contreras, Andres & Costanzo, V., 2020, In: eLife. 9, e54756.

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. Published

    ATRX-Deficient High-Grade Glioma Cells Exhibit Increased Sensitivity to RTK and PDGFR Inhibitors

    Pladevall Morera, David, Castejón-Griñán, M., Aguilera, P., Gaardahl, K., Ingham, Andreas, Brosnan-Cashman, J. A., Meeker, A. K. & Lopez-Contreras, Andres, 2022, In: Cancers. 14, 7, 1790.

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. Published

    Accuracy of MRI technique in measuring tendon cross-sectional area

    Couppé, Christian, Svensson, R. B., Elbrønd (Bibs), Vibeke Sødring, Hansen, P., Kjær, Michael & Magnusson, Stig Peter, 2014, In: Clinical Physiology and Functional Imaging. 34, 3, p. 237-241 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  40. Published

    Acquired Localized Cutis Laxa due to Increased Elastin Turnover

    Nygaard, R. H., Maynard, S., Schjerling, P., Kjær, M., Qvortrup, Klaus, Bohr, Vilhelm, Rasmussen, Lene Juel, Jemec, Gregor & Heidenheim, M., 14 Jun 2016, In: Case Reports in Dermatology. 8, 1, p. 42-51 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. Published

    Activated protein synthesis and suppressed protein breakdown signaling in skeletal muscle of critically ill patients

    Jespersen, J. G., Nedergaard, A., Reitelseder, S., Mikkelsen, U. R., Dideriksen, K. J., Agergaard, J., Kreiner, F., Pott, Frank Christian, Schjerling, P. & Kjær, Michael, 2011, In: P L o S One. 6, 3, p. e18090

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. Published

    Activation of satellite cells and the regeneration of human skeletal muscle are expedited by ingestion of nonsteroidal anti-inflammatory medication

    Mackey, Abigail, Rasmussen, L. K., Kadi, F., Schjerling, Peter, Helmark, I. C., Ponsot, E., Aagaard, P., Durigan, J. L. Q. & Kjær, Michael, 2 Mar 2016, In: FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 30, 6, p. 2266-2281

    Research output: Contribution to journal › Journal article › Research › peer-review

  43. Published

    Activation of the ATR kinase by the RPA-binding protein ETAA1

    Haahr, Peter Thorlund, Hoffmann, Saskia, Tollenaere, M. A. X., Ho, T., Toledo Lazaro, L. I., Mann, Matthias, Bekker-Jensen, Simon Holst, Räschle, M. & Mailand, Niels, Nov 2016, In: Nature Cell Biology. 18, 11, p. 1196–1207

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Published

    Active role of capillary pericytes during stimulation-induced activity and spreading depolarization

    Khennouf, Lila, Gesslein, B., Brazhe, A., Octeau, J. C., Kutuzov, Nikolay, Khakh, B. S. & Lauritzen, Martin, 2018, In: Brain. 141, 7, p. 2032-2046 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  45. Published

    Activity-Dependent Calcium, Oxygen, and Vascular Responses in a Mouse Model of Familial Hemiplegic Migraine Type 1

    Khennouf, Lila, Gesslein, B., Lind, Barbara Lykke, van den Maagdenberg, A. M. J. M. & Lauritzen, Martin, Aug 2016, In: Annals of Neurology. 80, 2, p. 219-232

    Research output: Contribution to journal › Journal article › Research › peer-review

  46. Published

    Activity-dependent increases in local oxygen consumption correlate with post-synaptic currents in the mouse cerebellum in vivo: Calcium, synaptic currents and oxygen

    Mathiesen, C., Caesar, K., Thomsen, Kirsten Joan, Hoogland, T., Witgen, B. M., Brazhe, A. & Lauritzen, Martin, 14 Dec 2011, In: Journal of Neuroscience. 31, 50, p. 18327-37 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. Published

    Activity-dependent increases in local oxygen consumption correlate with postsynaptic currents in the mouse cerebellum in vivo

    Mathiesen, C., Caesar, K., Thomsen, K. E., Hoogland, T. M., Witgen, B. M., Brazhe, A. & Lauritzen, Martin, 2011, In: Journal of Neuroscience. 31, 50, p. 18327-37 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  48. Published

    Acute MUS81 depletion leads to replication fork slowing and a constitutive DNA damage response

    Xing, M., Wang, X., Palmai-Pallag, T., Shen, H., Helleday, T., Hickson, Ian David & Ying, S., 2015, In: OncoTarget. 6, 35, p. 37638-37646 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  49. Published

    Acute fatigue impairs neuromuscular activity of anterior cruciate ligament-agonist muscles in female team handball players

    Zebis, M. K., Bencke, J., Andersen, L. L., Alkjær, Tine, Suetta, Charlotte, Mortensen, P., Kjær, Michael, Aagaard, P., Zebis, M. K., Bencke, J., Andersen, L. L., Alkjaer, T., Suetta, C., Mortensen, P., Kjær, Michael & Aagaard, P., 2011, In: Scandinavian Journal of Medicine & Science in Sports Online. 21, 6, p. 833-40 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  50. Published

    Acute inactivation of the replicative helicase in human cells triggers MCM8-9-dependent DNA synthesis

    Natsume, T., Nishimura, K., Minocherhomji, S., Bhowmick, Rahul, Hickson, Ian David & Kanemaki, M. T., 2017, In: Genes & Development. 31, 8, p. 816-829 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  51. Published

    Adipocytes are present at human and murine myotendinous junctions

    Jakobsen, J. R., Jakobsen, N. R., Mackey, Abigail, Knudsen, A. B., Hannibal, Jens, Koch, M., Kjær, Michael & Krogsgaard, Michael R., 2021, In: Translational Sports Medicine. 4, 2, p. 223-230

    Research output: Contribution to journal › Journal article › Research › peer-review

  52. Published

    Adrenergic Regulation of Energy Metabolism

    Kjær, Michael & Lange, Kai, 2020, Endocrinology of Physical Activity and Sport. Humana Press, p. 153-159 (Contemporary Endocrinology).

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  53. Published

    Age and prior exercise in vivo determine the subsequent in vitro molecular profile of myoblasts and non-myogenic cells derived from human skeletal muscle

    Bechshøft, C. J. L., Jensen, S. M., Schjerling, P., Andersen, J. L., Svensson, R. B., Eriksen, C. S., Mkumbuzi, N. S., Kjær, Michael & Mackey, Abigail, Jun 2019, In: American Journal of Physiology: Cell Physiology. 316, 6, p. C898-C912

    Research output: Contribution to journal › Journal article › Research › peer-review

  54. Published

    Age-related myofiber atrophy in old mice is reversed by ten weeks voluntary high-resistance wheel running

    Olesen, A. T., Alchow-Moller, L., Bendixen, R. D., Kjær, Michael, Svensson, R. B., Andersen, J. L. & Magnusson, Stig Peter, 2021, In: Experimental Gerontology. 143, 111150.

    Research output: Contribution to journal › Journal article › Research › peer-review

  55. Published

    Aging and drug discovery

    Bakula, D., Aliper, A. M., Mamoshina, P., Petr, M. A., Teklu, A., Baur, J. A., Campisi, J., Ewald, C. Y., Georgievskaya, A., Gladyshev, V. N., Kovalchuk, O., Lamming, D. W., Luijsterburg, M. S., Martín-Montalvo, A., Maudsley, S., Mkrtchyan, G. V., Moskalev, A., Jay Olshansky, S., Ozerov, I. V., Pickett, A. & 3 others, Ristow, M., Zhavoronkov, A. & Scheibye-Knudsen, Morten, 2018, In: Aging. 10, 11, p. 3079-3088 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  56. Published

    Aging impairs the recovery in mechanical muscle function following 4 days of disuse

    Hvid, L. G., Suetta, Charlotte, Nielsen, J., Jensen, M. M., Frandsen, U., Ørtenblad, N., Kjær, Michael & Aagaard, P., Apr 2014, In: Experimental Gerontology. 52, p. 1-8 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  57. Published

    Aging, longevity and health

    Rasmussen, Lene Juel, Sander, M., Wewer, Ulla M. & Bohr, Vilhelm, 23 Jul 2011, In: Mechanisms of Ageing and Development. p. 522-32 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  58. Published

    Alterations of monocarboxylate transporter densities during hypoxia in brain and breast tumour cells

    Cheng, C., Edin, N. F. J., Lauritzen, K. H., Aspmodal, I., Christoffersen, S., Jian, L., Rasmussen, Lene Juel, Pettersen, E. O., Xiaoqun, G. & Bergersen, L. H., Jun 2012, In: Cellular oncology (Dordrecht). 35, 3, p. 217-27 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  59. Published

    Altered alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor function and expression in hippocampus in a rat model of attention-deficit/hyperactivity disorder (ADHD)

    Medin, T., Jensen, V., Skare, O., Storm-Mathisen, J., Hvalby, O. & Bergersen, L. H., 2019, In: Behavioural Brain Research. 360, p. 209-215 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  60. Published

    Alternative translation initiation generates a functionally distinct isoform of the stress-activated kinase MK2

    Trulley, P., Snieckute, Goda, Bekker-Jensen, D. B., Menon, M. B., Freund, R., Kotlyarov, A., Olsen, Jesper Velgaard, Diaz-Muñoz, M. D., Turner, M., Bekker-Jensen, Simon Holst, Gaestel, M. & Tiedje, C., 2018, bioRxiv, 46 p. (bioRxiv).

    Research output: Working paper › Preprint › Research

  61. Published

    An advanced glycation endproduct (AGE)-rich diet promotes accumulation of AGEs in Achilles tendon

    Skovgaard, D., Svensson, R. B., Scheijen, J., Eliasson, P., Mogensen, P., Hag, Anne Mette Fisker, Kjær, Michael, Schalkwijk, C. G., Schjerling, P., Magnusson, Stig Peter & Couppé, C., Mar 2017, In: Physiological Reports. 5, 6, 7 p., e13215.

    Research output: Contribution to journal › Journal article › Research › peer-review

  62. Published

    An anti-inflammatory phenotype in visceral adipose tissue of old lean mice, augmented by exercise

    Ziegler, A. K., Damgaard, A., Mackey, Abigail, Schjerling, Peter, Magnusson, Stig Peter, Olesen, A. T., Kjær, Michael & Schéele, Camilla Charlotte Nielsen, 2019, In: Scientific Reports. 9, 11 p., 12069.

    Research output: Contribution to journal › Journal article › Research › peer-review

  63. Published

    Analysis of the antimicrobial susceptibility of the ionizing radiation-resistant bacterium Deinococcus radiodurans: implications for bioremediation of radioactive waste

    Bouchami, O., Sghaier, H., Desler, Claus, Lazim, H., Saidi, M., Rasmussen, Lene Juel & Ben Hassan, A., 2011, In: Annals of Microbiology.

    Research output: Contribution to journal › Journal article › Research › peer-review

  64. Published

    Anaphase: a fortune-teller of genomic instability

    Bizard, A. H. & Hickson, Ian David, Jun 2018, In: Current Opinion in Cell Biology. 52, p. 112-119 8 p.

    Research output: Contribution to journal › Review › Research › peer-review

  65. Published

    Application of a 5-tiered scheme for standardized classification of 2,360 unique mismatch repair gene variants in the InSiGHT locus-specific database

    Thompson, B. A., Spurdle, A. B., Plazzer, J-P., Greenblatt, M. S., Akagi, K., Al-Mulla, F., Bapat, B., Bernstein, I., Capellá, G., den Dunnen, J. T., du Sart, D., Fabre, A., Farrell, M. P., Farrington, S. M., Frayling, I. M., Frebourg, T., Goldgar, D. E., Heinen, C. D., Holinski-Feder, E., Kohonen-Corish, M. & 31 others, Robinson, K. L., Leung, S. Y., Martins, A., Moller, P., Morak, M., Nystrom, M., Peltomaki, P., Pineda, M., Qi, M., Ramesar, R., Rasmussen, Lene Juel, Royer-Pokora, B., Scott, R. J., Sijmons, R., Tavtigian, S. V., Tops, C. M., Weber, T., Wijnen, J., Woods, M. O., Macrae, F., Genuardi, M., Castillejo, A., Sexton, A., Chan, A. K. W., Viel, A., Blanco, A., French, A., Laner, A., Wagner, A., van den Ouweland, A. & on behalf of InSiGHT, O. B. O. I., Feb 2014, In: Nature Genetics. 46, 2, p. 107-115 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  66. Published

    Approaches to diagnose DNA mismatch repair gene defects in cancer

    Peña-Diaz, J. & Rasmussen, Lene Juel, Feb 2016, In: DNA Repair. 38, p. 147-154 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  67. Published

    Artificial intelligence for aging and longevity research: Recent advances and perspectives

    Zhavoronkov, A., Mamoshina, P., Vanhaelen, Q., Scheibye-Knudsen, Morten, Moskalev, A. & Aliper, A., 2019, In: Ageing Research Reviews. 49, p. 49-66 18 p.

    Research output: Contribution to journal › Review › Research › peer-review

  68. Published

    Assessing Genetic Variants of Uncertain Significance: The Example of Lynch Syndrome

    Rasmussen, Lene Juel & Heinen, C. D., 15 Apr 2014

    Research output: Other contribution › Net publication - Internet publication › Communication

  69. Published

    Assessment of satellite cell number and activity status in human skeletal muscle biopsies

    Mackey, A. L., Kjær, Michael, Charifi, N., Henriksson, J., Bojsen-Moller, J., Holm, L. & Kadi, F., Sep 2009, In: Muscle & Nerve. 40, 3, p. 455-465 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  70. Published

    Associations between xerostomia, histopathological alterations, and autonomic innervation of labial salivary glands in men in late midlife

    Sørensen, Christiane Elisabeth, Larsen, J. O., Reibel, Jesper, Lauritzen, Martin, Mortensen, Erik Lykke, Osler, Merete & Pedersen, Anne Marie Lynge, Sep 2014, In: Experimental Gerontology. 57, p. 211-217 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  71. Published

    Associations of subjective vitality with DNA damage, cardiovascular risk factors and physical performance

    Maynard, S., Keijzers, G., Hansen, Åse Marie, Osler, Merete, Molbo, Drude, Bendix, L., Møller, Peter, Loft, Steffen, Moreno-Villanueva, M., Bürkle, A., Hvitby, C. P., Schurman, S. H., Stevnsner, T. V., Rasmussen, Lene Juel, Avlund, K. & Bohr, Vilhelm, Jan 2015, In: Acta Physiologica (Print). 213, 1, p. 156-170 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  72. Published

    Astrocytes gate synaptic transmission from unmyelinated sensory afferents

    Perrier, Jean-Francois Marie, Christensen, R. K., Delgado-Lezama, R., Russo, R., Lind, Barbara Lykke, Alcocer, E. L., Fabbiani, G., Schmitt, Nicole, Lauritzen, Martin, Petersen, A. V. & Carlsen, E. M., Aug 2015, In: Glia. 63, S1, p. E241-E241 T08-22B .

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  73. Published

    Autophagy guards tendon homeostasis

    Montagna, C., Svensson, R. B., Bayer, M. L., Rizza, S., Maiani, E., Yeung, Ching-Yan Chloé, Filomeni, G. & Kjær, Michael, 2022, In: Cell Death and Disease. 13, 4, 402.

    Research output: Contribution to journal › Journal article › Research › peer-review

  74. Published

    BLM and RMI1 Alleviate RPA Inhibition of TopoIIIa Decatenase Activity

    Yang, J., Bachrati, C. Z., Hickson, Ian David & Brown, G. W., Jul 2012, In: P L o S One. 7, 7, p. e41208

    Research output: Contribution to journal › Journal article › Research › peer-review

  75. Published

    BLM has early and late functions in homologous recombination repair in mouse embryonic stem cells

    Chu, W. K., Hanada, K., Kanaar, R. & Hickson, Ian David, 19 Aug 2010, In: Oncogene. 29, 33, p. 4705-14 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  76. Published

    Bacterial infection increases risk of carcinogenesis by targeting mitochondria

    Strickertsson, J. A. B., Desler, Claus & Rasmussen, Lene Juel, Dec 2017, In: Seminars in Cancer Biology. 47, p. 95-100 6 p.

    Research output: Contribution to journal › Review › Research › peer-review

  77. Published

    Basic Components of Connective Tissues and Extracellular Matrix: Elastin, Fibrillin, Fibulins, Fibrinogen, Fibronectin, Laminin, Tenascins and Thrombospondins

    Halper, J. & Kjær, Michael, 2014, Progress in Heritable Soft Connective Tissue Diseases. Vol. 802. p. 31-47 17 p. (Advances in Experimental Medicine and Biology).

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  78. Published

    Behandling af akutte muskelskader

    Bayer, M. L., Mackey, Abigail, Magnusson, Stig Peter, Krogsgaard, Michael R. & Kjær, Michael, 18 Feb 2019, In: Ugeskrift for Laeger. 181, 8, 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  79. Published

    Behavioural effects of high fat diet in a mutant mouse model for the schizophrenia risk gene neuregulin 1: High fat diet in schizophrenia mouse model

    Holm-hansen, S., Low, J. K., Zieba, J., Gjedde, Albert, Bergersen, L. H. & Karl, T., 1 Mar 2016, In: Genes, Brain and Behavior. 15, 3, p. 295-304

    Research output: Contribution to journal › Journal article › Research › peer-review

  80. Published

    Bengt Saltin (1935-2014)

    Bangsbo, Jens, Kjær, Michael & Hellsten, Ylva, 2014, In: Journal of Physiology. 592, 23, p. 5149-5151 3 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  81. Published

    Bi-directional routing of DNA mismatch repair protein human exonuclease 1 to replication foci and DNA double strand breaks

    Liberti, S. E., Andersen, S. D., Wang, J., May, A., Miron, S., Perderiset, M., Keijzers, G., Nielsen, Finn Cilius, Charbonnier, J., Bohr, Vilhelm & Rasmussen, Lene Juel, 2 Jan 2011, In: DNA Repair. 10, 1, p. 73-86 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  82. Published

    Bindevæv og muskler, funktion, opbygning og basale egenskaber

    Langberg, Henning, Kjær, Michael, Krogsgaard, M., Rheinländer, P. & Larsen, A. E., 2009, Ortopædkirurgi- for ergoterapeuter og fysioterapeuter. København: Munksgaard , p. 29-50 21 p.

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research

  83. Published

    Biochemical and Mass Spectrometry-Based Approaches to Profile SUMOylation in Human Cells

    Kessler, B. M., Bursomanno, S., McGouran, J. F., Hickson, Ian David & Liu, Ying, 2017, Activity-Based Proteomics: Methods and Protocols. Overkleeft, H. S. & Florea, B. I. (eds.). Humana Press, Vol. 1491. p. 131-144 14 p. (Methods in Molecular Biology, Vol. 1491).

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  84. Published

    Biochemical characterization of MLH3 missense mutations does not reveal an apparent role of MLH3 in Lynch syndrome

    Ou, J., Rasmussen, M., Westers, H., Andersen, S. D., Jager, P. O., Kooi, K. A., Niessen, R. C., Eggen, B. J. L., Nielsen, Finn Cilius, Kleibeuker, J. H., Sijmons, R. H., Rasmussen, Lene Juel & Hofstra, R. M. W., 2009, In: Genes, Chromosomes & Cancer. 48, 4, p. 340-50 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  85. Published

    Bioenergetic Changes during Differentiation of Human Embryonic Stem Cells along the Hepatic Lineage

    Hopkinson, B. M., Desler, Claus, Kalisz, M., Vestentoft, P. S., Rasmussen, Lene Juel & Bisgaard, Hanne Cathrine, 2017, In: Oxidative Medicine and Cellular Longevity. 2017, 11 p., 5080128.

    Research output: Contribution to journal › Journal article › Research › peer-review

  86. Published

    Blood Biochemistry Analysis to Detect Smoking Status and Quantify Accelerated Aging in Smokers

    Mamoshina, P., Kochetov, K., Cortese, F., Kovalchuk, A., Aliper, A., Putin, E., Scheibye-Knudsen, Morten, Cantor, C. R., Skjodt, N. M., Kovalchuk, O. & Zhavoronkov, A., 2019, In: Scientific Reports. 9, 10 p., 142.

    Research output: Contribution to journal › Journal article › Research › peer-review

  87. Published

    Bloom syndrome DNA helicase deficiency is associated with oxidative stress and mitochondrial network changes

    Subramanian, V., Rodemoyer, B., Shastri, V., Rasmussen, Lene Juel, Desler, Claus & Schmidt, K. H., 2021, In: Scientific Reports. 11, 2157.

    Research output: Contribution to journal › Journal article › Research › peer-review

  88. Published

    Bone blood flow and metabolism in humans: Effect of muscular exercise and other physiological perturbations

    Heinonen, I., Kemppainen, J., Kaskinoro, K., Langberg, Henning, Knuuti, J., Boushel, R., Kjær, Michael & Kalliokoski, K. K., 21 Dec 2012, In: Journal of Bone and Mineral Research. 28, 5, p. 1068–1074

    Research output: Contribution to journal › Journal article › Research › peer-review

  89. Published

    Brain Responses to Passive Sensory Stimulation Correlate With Intelligence

    Horwitz, Anna, Klemp, Marc Patrick Brag, Horwitz, Henrik, Thomsen, M. D., Rostrup, Egill, Mortensen, Erik Lykke, Osler, Merete, Lauritzen, Martin & Benedek, K., 2019, In: Frontiers in Aging Neuroscience. 11, 17 p., 201.

    Research output: Contribution to journal › Journal article › Research › peer-review

  90. Published

    Brain energy supply and metabolism in aging

    Lauritzen, Martin, Nov 2015, In: Acta Physiologica. 215, S705, p. 59-59 1 p., S18-1.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  91. Published

    CNOT6: A Novel Regulator of DNA Mismatch Repair

    Song, P., Liu, S., Liu, D., Keijzers, G., Bakula, Daniela Janina, Duan, S., de Wind, N., Ye, Z., Vakhrushev, Sergey, Scheibye-Knudsen, Morten & Rasmussen, Lene Juel, 2022, In: Cells. 11, 3, 521.

    Research output: Contribution to journal › Journal article › Research › peer-review

  92. Published

    CaMKII-dependent endoplasmic reticulum fission by whisker stimulation and during cortical spreading depolarization

    Kucharz, Krzysztof & Lauritzen, Martin, 2018, In: Brain. 141, 4, p. 1049-1062 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  93. Published

    Capillary pericytes regulate cerebral blood flow in health and disease

    Hall, C. N., Reynell, C., Gesslein, B., Hamilton, N. B., Mishra, A., Sutherland, B. A., O'Farrell, F. M., Buchan, A. M., Lauritzen, Martin & Attwell, D., Apr 2014, In: Nature. 508, 7494, p. 55-60 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  94. Published

    Carbon-14 bomb pulse dating shows that tendinopathy is preceded by years of abnormally high collagen turnover

    Heinemeier, K. M., Schjerling, Peter, Øhlenschlæger, Tommy Frisgaard, Eismark, C., Olsen, J. & Kjær, Michael, Sep 2018, In: FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 32, 9, p. 4763-4775 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  95. Published

    Celebrating the 30th anniversary of our journal

    Lauritzen, Martin & Dirnagl, U., Jul 2012, In: Journal of Cerebral Blood Flow and Metabolism. 32, 7, p. 1097 1 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  96. Published

    Cellular homeostatic tension and force transmission measured in human engineered tendon

    Giannopoulos, A., Svensson, R. B., Heinemeier, K. M., Schjerling, P., Kadler, K. E., Holmes, D. F., Kjær, Michael & Magnusson, Stig Peter, 2018, In: Journal of Biomechanics. 78, p. 161-165 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  97. Published

    Centriolar satellites: key mediators of centrosome functions

    Tollenaere, M. A. X., Mailand, Niels & Bekker-Jensen, Simon Holst, Jan 2015, In: Cellular and molecular life sciences : CMLS. 73, 1, p. 11-23 13 p.

    Research output: Contribution to journal › Review › Research › peer-review

  98. Published

    Cerebral haemodynamic response or excitability is not affected by sildenafil

    Kruuse, Christina Rostrup, Hansen, Adam Espe, Larsson, Henrik Bo Wiberg, Lauritzen, Martin & Rostrup, Egill, Apr 2009, In: Journal of Cerebral Blood Flow and Metabolism. 29, 4, p. 830-9 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  99. Published

    Characterising the proximal patellar tendon attachment and its relationship to skeletal maturity in adolescent ballet dancers

    Rudavsky, A., Cook, J., Magnusson, Stig Peter, Kjær, Michael & Docking, S., Apr 2017, In: Muscles, Ligaments and Tendons Journal. 7, 2, p. 306-314 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  100. Published

    Characterization of a highly conserved binding site of Mlh1 required for exonuclease I-dependent mismatch repair

    Dherin, C., Gueneau, E., Francin, M., Nunez, M., Miron, S., Liberti, S. E., Rasmussen, Lene Juel, Zinn-Justin, S., Gilquin, B., Charbonnier, J. & Boiteux, S., 2009, In: Molecular and Cellular Biology. 29, 3, p. 907-18 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

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