Damage and Repair

  1. Published

    A Novel Rrm3 Function in Restricting DNA Replication via an Orc5-Binding Domain Is Genetically Separable from Rrm3 Function as an ATPase/Helicase in Facilitating Fork Progression

    Syed, S., Desler, Claus, Rasmussen, Lene Juel & Schmidt, K. H., Dec 2016, In: P L o S Genetics. 12, 12, 28 p., e1006451.

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    A Role for BLM in Double-Strand Break Repair Pathway Choice: Prevention of CtIP/Mre11-Mediated Alternative Nonhomologous End-Joining.

    Grabarz, A., Guirouilh-Barbat, J., Barascu, A., Pennarun, G., Genet, D., Rass, E., Germann, S. M., Bertrand, P., Hickson, Ian David & Lopez, B. S., 17 Oct 2013, In: Cell Reports. 5, 1, p. 21-28 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    A Single Conserved Residue Mediates Binding of the Ribonucleotide Reductase Catalytic Subunit RRM1 to RRM2 and Is Essential for Mouse Development

    Specks, J., Lecona, E., Lopez-Contreras, Andres & Fernandez-Capetillo, O., Sep 2015, In: Molecular and Cellular Biology. 35, 17, p. 2910-2917 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    A Small Molecule Inhibitor of the BLM Helicase Modulates Chromosome Stability in Human Cells

    Nguyen, G. H., Dexheimer, T. S., Rosenthal, A. S., Chu, W. K., Singh, D. K., Mosedale, G., Bachrati, C. Z., Schultz, L., Sakurai, M., Savitsky, P., Abu, M., McHugh, P. J., Bohr, Vilhelm, Harris, C. C., Jadhav, A., Gileadi, O., Maloney, D. J., Simeonov, A. & Hickson, Ian David, 24 Jan 2013, In: Chemistry & Biology. 20, 1, p. 55-62 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    A critical role for astrocytes in hypercapnic vasodilation in brain

    Howarth, C., Sutherland, B. A., Choi, H. B., Martin, C., Lind, Barbara Lykke, Khennouf, Lila, LeDue, J. M., Pakan, J. M. P., Ko, R. W., Ellis-Davies, G. C. R., Lauritzen, Martin, Sibson, N. R., Buchan, A. M. & MacVicar, B. A., 2017, In: The Journal of Neuroscience. 37, 9, p. 2403-2414 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    A cross-sectional study of functional and metabolic changes during aging through the lifespan in male mice

    Petr, Michael Angelo, Alfaras, I., Krawcyzk, M., Bair, W. N., Mitchell, S. J., Morrell, C. H., Studenski, S. A., Price, N. L., Fishbein, K. W., Spencer, R. G., Scheibye-Knudsen, Morten, Lakatta, E. G., Ferrucci, L., Aon, M. A., Bernier, M. & de Cabo, R., 2021, In: eLife. 10, 25 p., e62952.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    A defined human aging phenome

    Andreassen, Søren Norge, Ben Ezra, Michael & Scheibye-Knudsen, Morten, 2019, In: Aging. 11, 15, p. 5786-5806 21 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    A functional assay–based procedure to classify mismatch repair gene variants in Lynch syndrome

    Drost, M., Tiersma, Y., Thompson, B. A., Frederiksen, J. H., Keijzers, G., Glubb, D., Kathe, S., Osinga, J., Westers, H., Pappas, L., Boucher, K. M., Molenkamp, S., Zonneveld, J. B., van Asperen, C. J., Goldgar, D. E., Wallace, S. S., Sijmons, R. H., Spurdle, A. B., Rasmussen, L. J., Greenblatt, M. S. & 2 others, de Wind, N. & Tavtigian, S. V., 2019, In: Genetics in Medicine. 21, p. 1486–1496

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    A high-fat diet and NAD+ activate sirt1 to rescue premature aging in cockayne syndrome

    Scheibye-Knudsen, M., Mitchell, S. J., Fang, E. F., Iyama, T., Ward, T., Wang, J., Dunn, C. A., Singh, N., Veith, S., Hasan-Olive, M. M., Mangerich, A., Wilson, M. A., Mattson, M. P., Bergersen, L. H., Cogger, V. C., Warren, A., Le Couteur, D. G., Moaddel, R., Wilson, D. M., Croteau, D. L. & 2 others, De Cabo, R. & Bohr, Vilhelm, 4 Nov 2014, In: Cell Metabolism. 20, 5, p. 840-855 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    A ketogenic diet accelerates neurodegeneration in mice with induced mitochondrial DNA toxicity in the forebrain

    Lauritzen, K. H., Hasan-Olive, M. M., Regnell, C. E., Kleppa, L., Scheibye-Knudsen, Morten, Gjedde, Albert, Klungland, A., Bohr, Vilhelm, Storm-Mathisen, J. & Bergersen, L. H., Dec 2016, In: Neurobiology of Aging. 48, p. 34-47

    Research output: Contribution to journalJournal articleResearchpeer-review

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