- Published
Upregulation of the lactate transporter monocarboxylate transporter 1 at the blood-brain barrier in a rat model of attention-deficit/hyperactivity disorder suggests hyperactivity could be a form of self-treatment
Medin, T., Medin, H., Hefte, M. B., Storm-Mathisen, J. & Bergersen, L. H., 2019, In: Behavioural Brain Research. 360, p. 279-285 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Altered alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor function and expression in hippocampus in a rat model of attention-deficit/hyperactivity disorder (ADHD)
Medin, T., Jensen, V., Skare, O., Storm-Mathisen, J., Hvalby, O. & Bergersen, L. H., 2019, In: Behavioural Brain Research. 360, p. 209-215 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Pooled analysis of frontal lobe transcriptomic data identifies key mitophagy gene changes in Alzheimer's disease brain
Mei, T., Li, Yuan, Orduña Dolado, A., Li, Zhiquan, Andersson, Robin, Berliocchi, Laura & Rasmussen, Lene Juel, 2023, In: Frontiers in Aging Neuroscience. 15, 14 p., 1101216.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Tendon blood flow, angiogenesis, and tendinopathy pathogenesis
Merkel, M. F. R., Hellsten, Ylva, Magnusson, Stig Peter & Kjær, Michael, 2021, In: Translational Sports Medicine. 4, 6, p. 756-771 16 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Meeting Report: Aging Research and Drug Discovery
Meron, E., Thaysen, M., Angeli, S., Antebi, A., Barzilai, N., Baur, J. A., Bekker-Jensen, S., Birkisdottir, M., Bischof, E., Bruening, J., Brunet, A., Buchwalter, A., Cabreiro, F., Cai, S., Chen, B. H., Ermolaeva, M., Ewald, C. Y., Ferrucci, L., Florian, M. C., Fortney, K. & 58 others, , 2022, In: Aging. 14, 2, p. 530-543 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Local NSAID infusion inhibits satellite cell proliferation in human skeletal muscle after eccentric exercise
Mikkelsen, U. R., Langberg, Henning, Helmark, I. C., Skovgaard, D., Andersen, L. L., Kjær, Michael & Mackey, Abigail, Nov 2009, In: Journal of Applied Physiology. 107, 5, p. 1600-1611 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Life-long endurance exercise in humans: circulating levels of inflammatory markers and leg muscle size
Mikkelsen, U. R., Couppé, Christian, Karlsen, Anders, Grosset, J. F., Schjerling, Peter, Mackey, Abigail, Klausen, H. H., Magnusson, Stig Peter & Kjær, Michael, 30 Nov 2013, In: Mechanisms of Ageing and Development. 134, 11-12, p. 531-40 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Local NSAID infusion does not affect protein synthesis and gene expression in human muscle after eccentric exercise
Mikkelsen, U. R., Schjerling, P., Langberg, Henning, Reitelseder, S., Helmark, I. C., Holm, L., Skovgaard, D., Kjær, Michael & Heinemeier, K. M., Oct 2011, In: Scandinavian Journal of Medicine & Science in Sports. 21, 5, p. 630-644 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The heat shock protein response following eccentric exercise in human skeletal muscle is unaffected by local NSAID infusion
Mikkelsen, U. R., Paulsen, G., Schjerling, Peter, Helmark, I. C., Langberg, Henning, Kjær, Michael & Heinemeier, K. M., 2013, In: European Journal of Applied Physiology. 113, 7, p. 1883-1893 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Skeletal muscle morphology and regulatory signalling in endurance-trained and sedentary individuals: The influence of ageing
Mikkelsen, U. R., Agergaard, J., Couppé, Christian, Grosset, J. F., Karlsen, Anders, Magnusson, Stig Peter, Schjerling, Peter, Kjær, Michael & Mackey, Abigail, Jul 2017, In: Experimental Gerontology. 93, p. 54-67Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Preserved skeletal muscle protein anabolic response to acute exercise and protein intake in well-treated rheumatoid arthritis patients
Mikkelsen, U. R., Dideriksen, K., Andersen, M. B., Boesen, A., Malmgaard-Clausen, N. M., Sørensen, I. J., Schjerling, Peter, Kjær, Michael & Holm, L., 2015, In: Arthritis Research & Therapy (Print). 17, p. 271Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Replication stress activates DNA repair synthesis in mitosis
Minocherhomji, S., Ying, S., Bjerregaard, Victoria Alexandra, Bursomanno, S., Aleliunaite, A., Wu, Wei, Mankouri, H. W., Shen, H., Liu, Ying & Hickson, Ian David, 10 Dec 2015, In: Nature. 528, 7581, p. 286-90 5 p.Research output: Contribution to journal › Letter › Research › peer-review
- Published
Structure-specific endonucleases: guardians of fragile site stability
Minocherhomji, S. & Hickson, Ian David, May 2014, In: Trends in Cell Biology. 24, 5, p. 321-327 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effects of Sex, Strain, and Energy Intake on Hallmarks of Aging in Mice
Mitchell, S. J., Madrigal-Matute, J., Scheibye-Knudsen, M., Fang, E., Aon, M., Gonzalez-Reyes, J. A., Cortassa, S., Kaushik, S., Gonzalez-Freire, M., Patel, B., Wahl, D., Ali, A., Calvo-Rubio, M., Buron, M. I., Guiterrez, V., Ward, T. M., Palacios, H. H., Cai, H., Frederick, D. W., Hine, C. & 27 others, , 14 Jun 2016, In: Cell Metabolism. 23, 6, p. 1093-1112Research output: Contribution to journal › Journal article › Research › peer-review
- Published
ARDD 2020: from aging mechanisms to interventions
Mkrtchyan, G. V., Abdelmohsen, K., Andreux, P., Bagdonaite, I., Barzilai, N., Brunak, S., Cabreiro, F., Cabo, R. D., Campisi, J., Cuervo, A. M., Demaria, M., Ewald, C. Y., Fang, E. F., Faragher, R., Ferrucci, L., Freund, A., Silva-García, C. G., Georgievskaya, A., Gladyshev, V. N., Glass, D. J. & 46 others, , 2020, In: Aging. 12, 24, p. 24486-24503 18 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
High-confidence cancer patient stratification through multiomics investigation of DNA repair disorders
Mkrtchyan, Garik, Veviorskiy, A., Izumchenko, E., Shneyderman, A., Pun, F. W., Ozerov, I. V., Aliper, A., Zhavoronkov, A. & Scheibye-Knudsen, Morten, 2022, In: Cell Death and Disease. 13, 11, 999.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Development and evaluation of human AP endonuclease inhibitors in melanoma and glioma cell lines
Mohammed, M. Z., Vyjayanti, V. N., Laughton, C. A., Dekker, L. V., Fischer, P. M., Wilson, D. M., Abbotts, R., Shah, S., Patel, P. M., Hickson, Ian David & Madhusudan, S., 15 Feb 2011, In: British Journal of Cancer Management. 104, 4, p. 653-63 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cyclin E overexpression in the Drosophila accessory gland induces tissue dysplasia
Molano-Fernández, M., Hickson, Ian David & Herranz, Hector, 2023, In: Frontiers in Cell and Developmental Biology. 10, 992253.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Autophagy guards tendon homeostasis
Montagna, C., Svensson, R. B., Bayer, M. L., Rizza, S., Maiani, E., Yeung, Ching-Yan Chloé, Filomeni, G. & Kjær, Michael, 2022, In: Cell Death and Disease. 13, 4, 402.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The lactate receptor, G-protein-coupled receptor 81/hydroxycarboxylic acid receptor 1: Expression and action in brain
Morland, C., Lauritzen, K. H., Puchades, M., Holm-Hansen, S., Andersson, K., Gjedde, Albert, Attramadal, H., Storm-Mathisen, J. & Bergersen, L. H., Jul 2015, In: Journal of Neuroscience Research. 93, 7, p. 1045-1055 11 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Exercise induces cerebral VEGF and angiogenesis via the lactate receptor HCAR1
Morland, C., Andersson, K. A., Haugen, O. P., Hadzic, A., Kleppa, L., Gille, A., Rinholm, J. E., Palibrk, V., Diget, E. H., Kennedy, L. H., Stolen, T., Hennestad, E., Moldestad, O., Cai, Y., Puchades, M., Offermanns, S., Vervaeke, K., Bjoras, M., Wisloff, U., Storm-Mathisen, J. & 1 others, , 2017, In: Nature Communications. 8, 9 p., 15557.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The deubiquitylating enzyme USP44 counteracts the DNA double-strand break response mediated by the RNF8 and RNF168 ubiquitin ligases
Mosbech, A., Lukas, Claudia, Bekker-Jensen, Simon Holst & Mailand, Niels, 24 Apr 2013, In: Journal of Biological Chemistry. 288, p. 16579-16587 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
DVC1 (C1orf124) is a DNA damage-targeting p97 adaptor that promotes ubiquitin-dependent responses to replication blocks
Mosbech, A., Gibbs-Seymour, I., Kagias, K., Thorslund, T., Beli, P., Povlsen, L., Nielsen, S. V., Smedegaard, S., Sedgwick, G., Lukas, Claudia, Hartmann-Petersen, Rasmus, Lukas, Jiri, Choudhary, Chunaram, Pocock, R. D. J., Bekker-Jensen, Simon Holst & Mailand, Niels, 2012, In: Nature Structural and Molecular Biology. 19, 11, p. 1084-92 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Proteomics Reveals Global Regulation of Protein SUMOylation by ATM and ATR Kinases during Replication Stress
Munk, S., Sigurðsson, J. O., Xiao, Z., Batth, Tanveer Singh, Franciosa, Giulia, von Stechow, L., Lopez-Contreras, Andres, Vertegaal, A. C. O. & Olsen, Jesper Velgaard, 2017, In: Cell Reports. 21, 2, p. 546-558 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Developing T lymphocytes are uniquely sensitive to a lack of topoisomerase III alpha
Mönnich, M., Hess, I., Wiest, W., Bachrati, C., Hickson, Ian David, Schorpp, M. & Boehm, T., Sep 2010, In: European Journal of Immunology. 40, 9, p. 2379-84 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Immobilization Decreases FOXO3a Phosphorylation and Increases Autophagy-Related Gene and Protein Expression in Human Skeletal Muscle
Møller, A. B., Vendelbo, M. H., Schjerling, Peter, Couppé, Christian, Møller, N., Kjær, Michael, Hansen, M. & Jessen, N., 14 Jun 2019, In: Frontiers in Physiology. 10, 14 p., 736.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Functional adaptation of tendon and skeletal muscle to resistance training in three patients with genetically verified classic Ehlers Danlos Syndrome
Møller, M. B., Kjær, Michael, Svensson, R. B., Andersen, J. L., Magnusson, Stig Peter & Nielsen, R. H., 2014, In: M.L.T.J. Muscles, Ligaments and Tendons Journal. 4, 3, p. 315-323 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Colorectal cancer incidences in Lynch syndrome: a comparison of results from the prospective lynch syndrome database and the international mismatch repair consortium
The European Hereditary Tumour Group (EHTG) and the International Mismatch Repair Consortium (IMRC), T. E. H. T. G. (. A. T. I. M. R. C. (., 2022, In: Hereditary Cancer in Clinical Practice. 20, 36.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cytoplasmic Citrate Flux Modulates the Immune Stimulatory NKG2D Ligand MICA in Cancer Cells
Møller, S. H., Mellergaard, M., Madsen, M., Bermejo, A. V., Jepsen, Stine Dam, Hansen, M. H., Høgh, R. I., Aldana, Blanca, Desler, Claus, Rasmussen, Lene Juel, Sustarsic, E. G., Gerhart-Hines, Zach, Daskalaki, E., Wheelock, C. E., Hiron, T. K., Lin, D., O'Callaghan, C. A., Wandall, Hans H., Andresen, Lars & Skov, Søren, 2020, In: Frontiers in Immunology. 11, 22 p., 1968.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The effect of acute exercise on collagen turnover in human tendons: influence of prior immobilization period
Mørch, L. S., Pingel, Jessica, Boesen, M., Kjær, Michael & Langberg, Henning, 2013, In: European Journal of Applied Physiology. 113, 2, p. 449-455 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Acute inactivation of the replicative helicase in human cells triggers MCM8-9-dependent DNA synthesis
Natsume, T., Nishimura, K., Minocherhomji, S., Bhowmick, Rahul, Hickson, Ian David & Kanemaki, M. T., 2017, In: Genes & Development. 31, 8, p. 816-829 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Spatial Transcriptomics Reveals Genes Associated with Dysregulated Mitochondrial Functions and Stress Signaling in Alzheimer Disease
Navarro, J. F., Croteau, D. L., Jurek, A., Andrusivova, Z., Yang, B., Wang, Y., Ogedegbe, B., Riaz, T., Støen, M., Desler, Claus, Rasmussen, Lene Juel, Tønjum, T., Galas, M. C., Lundeberg, J. & Bohr, Vilhelm, 2020, In: iScience. 23, 10, 42 p., 101556.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Type VI collagen turnover-related peptides—novel serological biomarkers of muscle mass and anabolic response to loading in young men
Nedergaard, A., Sun, S., Karsdal, M. A., Henriksen, K. S., Kjær, Michael, Lou, Y., He, Y., Zheng, Q. & Suetta, Charlotte, 2013, In: Journal of Cachexia, Sarcopenia and Muscle. 4, 4, p. 267-275 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effects of 2 weeks lower limb immobilization and two separate rehabilitation regimens on gastrocnemius muscle protein turnover signaling and normalization genes
Nedergaard, A., Jespersen, J. G., Pingel, Jessica, Christensen, B., Sroczynski, N., Langberg, Henning, Kjær, Michael & Schjerling, Peter, 28 Mar 2012, In: BMC Research Notes. 5, 1, p. 166 1 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Crystal structure of the Bloom's syndrome helicase indicates a role for the HRDC domain in conformational changes
Newman, J. A., Savitsky, P., Allerston, C. K., Bizard, A. H., Özer, Ö., Sarlós, K., Liu, Ying, Pardon, E., Steyaert, J., Hickson, Ian David & Gileadi, O., 2015, In: Nucleic Acids Research. 43, 10, p. 5221-35 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Regulation of gene expression by the BLM helicase correlates with the presence of G-quadruplex DNA motifs
Nguyen, G. H., Tang, W., Robles, A. I., Beyer, R. P., Gray, L. T., Welsh, J. A., Schetter, A. J., Kumamoto, K., Wang, X. W., Hickson, Ian David, Maizels, N., Monnat, R. J. & Harris, C. C., 8 Jul 2014, In: Proceedings of the National Academy of Sciences of the United States of America. 111, 27, p. 9905-10 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A Small Molecule Inhibitor of the BLM Helicase Modulates Chromosome Stability in Human Cells
Nguyen, G. H., Dexheimer, T. S., Rosenthal, A. S., Chu, W. K., Singh, D. K., Mosedale, G., Bachrati, C. Z., Schultz, L., Sakurai, M., Savitsky, P., Abu, M., McHugh, P. J., Bohr, Vilhelm, Harris, C. C., Jadhav, A., Gileadi, O., Maloney, D. J., Simeonov, A. & Hickson, Ian David, 24 Jan 2013, In: Chemistry & Biology. 20, 1, p. 55-62 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
PICH promotes mitotic chromosome segregation: Identification of a novel role in rDNA disjunction
Nielsen, Christian Friberg & Hickson, Ian David, 17 Oct 2016, In: Cell Cycle. 15, 20, p. 2704-2711 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
PICH promotes sister chromatid disjunction and co-operates with topoisomerase II in mitosis
Nielsen, Christian Friberg, Huttner, D., Bizard, A. H., Hirano, S., Li, T., Palmai-Pallag, T., Bjerregaard, Victoria Alexandra, Liu, Ying, Nigg, E. A., Wang, L. H. & Hickson, Ian David, 2015, In: Nature Communications. 6, 15 p., 8962.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Chronic alterations in growth hormone/insulin-like growth factor-I signaling lead to changes in mouse tendon structure
Nielsen, R. H., Clausen, N. M., Schjerling, Peter, Larsen, J. O., Martinussen, Torben, List, E. O., Kopchick, J. J., Kjær, Michael & Heinemeier, K. M., Feb 2014, In: Matrix Biology. 34, p. 96-104 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Low tendon stiffness and abnormal ultrastructure distinguish classic Ehlers-Danlos syndrome from benign joint hypermobility syndrome in patients
Nielsen, R. H., Couppé, Christian, Jensen, J. K., Olsen, M. R., Heinemeier, K. M., Malfait, F., Symoens, S., De Paepe, A., Schjerling, Peter, Magnusson, Stig Peter, Remvig, L. & Kjær, Michael, Nov 2014, In: FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 28, 11, p. 4668-4676 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Increase in tendon protein synthesis in response to insulin-like growth factor-I is preserved in elderly men
Nielsen, R. H., Holm, L., Malmgaard-Clausen, N. M., Reitelseder, S., Heinemeier, K. M. & Kjær, Michael, 1 Jan 2014, In: Journal of Applied Physiology. 116, 1, p. 42-6 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Tendon protein synthesis rate in classic Ehlers-Danlos patients can be stimulated with insulin-like growth factor-I
Nielsen, R. H., Holm, L., Jensen, J. K., Heinemeier, K. M., Remvig, L. & Kjær, Michael, 1 Oct 2014, In: Journal of Applied Physiology. 117, 7, p. 694-698 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Predicting the impact of Lynch syndrome-causing missense mutations from structural calculations
Nielsen, S. V., Stein, Amelie, Dinitzen, A. B., Papaleo, E., Tatham, M. H., Poulsen, E. G., Kassem, M. M., Rasmussen, Lene Juel, Lindorff-Larsen, Kresten & Hartmann-Petersen, Rasmus, 19 Apr 2017, In: PLoS Genetics. 13, 4, 26 p., e1006739.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Reduced GABAergic inhibition explains cortical hyperexcitability in the wobbler mouse model of ALS
Nieto-Gonzalez, J. L., Moser, J., Lauritzen, Martin, Schmitt-John, T. & Jensen, K., 1 Mar 2011, In: Cerebral Cortex. 21, 3, p. 625-35 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Efficacy of ATR inhibitors as single agents in Ewing sarcoma
Nieto-Soler, M., Morgado-Palacin, I., Lafarga, V., Lecona, E., Murga, M., Callen, E., Azorin, D., Alonso, J., Lopez-Contreras, Andres, Nussenzweig, A. & Fernandez-Capetillo, O., 26 Aug 2016, In: OncoTarget. 7, 37, p. 58759-58767Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Inflammation relates to resistance training-induced hypertrophy in elderly patients
Norheim, K. L., Cullum, C. K., Andersen, J. L., Kjær, Michael & Karlsen, Anders, Jun 2017, In: Medicine and Science in Sports and Exercise. 49, 6, p. 1079-1085 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Handgrip strength shows no improvements in geriatric patients with persistent inflammation during hospitalization
Norheim, K. L., Bautmans, I. & Kjær, Michael, 1 Dec 2017, In: Experimental Gerontology. 99, p. 115-119 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Skeletal muscle morphology, protein synthesis and gene expression in Ehlers Danlos Syndrome
Nygaard, R. H., Jensen, J. K., Voermans, N. C., Heinemeier, K. M., Schjerling, Peter, Holm, L., Agergaard, J., Mackey, Abigail, Andersen, J. L., Remvig, L. & Kjær, Michael, Aug 2017, In: Journal of Applied Physiology. 123, 2, p. 482-488Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Acquired Localized Cutis Laxa due to Increased Elastin Turnover
Nygaard, R. H., Maynard, S., Schjerling, P., Kjær, M., Qvortrup, Klaus, Bohr, Vilhelm, Rasmussen, Lene Juel, Jemec, Gregor & Heidenheim, M., 14 Jun 2016, In: Case Reports in Dermatology. 8, 1, p. 42-51 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
In acutely admitted geriatric patients, offering increased physical activity during hospitalization decreases length of stay and can improve mobility
Oestergaard, A. S., Mathiesen, M. H., Karlsen, Anders, Turtumoeygaard, I. F., Vahlgren, J., Kjær, Michael & Beyer, N., 2018, In: Translational Sports Medicine. 1, 1, p. 46-53Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Ubiquitin-like protein UBL5 promotes the functional integrity of the Fanconi anemia pathway
Oka, Y., Bekker-Jensen, Simon Holst & Mailand, Niels, 9 Apr 2015, In: E M B O Journal. 34, p. 1385-1398Research output: Contribution to journal › Journal article › Research › peer-review
- Published
UBL5 is essential for pre-mRNA splicing and sister chromatid cohesion in human cells
Oka, Y., Varmark, H., Vitting-Seerup, K., Beli, P., Waage, J. E., Hakobyan, A., Mistrik, M., Choudhary, Chunaram, Rohde, M., Bekker-Jensen, Simon Holst & Mailand, Niels, 2014, In: E M B O Reports. 15, 9, p. 956-964 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Age-related myofiber atrophy in old mice is reversed by ten weeks voluntary high-resistance wheel running
Olesen, A. T., Alchow-Moller, L., Bendixen, R. D., Kjær, Michael, Svensson, R. B., Andersen, J. L. & Magnusson, Stig Peter, 2021, In: Experimental Gerontology. 143, 111150.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
New methodologies in ageing research
Osborne, Brenna, Bakula, Daniela Janina, Ben Ezra, Michael, Dresen, C., Hartmann, E., Kristensen, S. M., Mkrtchyan, Garik, Nielsen, M. H., Petr, Michael Angelo & Scheibye-Knudsen, Morten, 2020, In: Ageing Research Reviews. 62, 11 p., 101094.Research output: Contribution to journal › Review › Research › peer-review
- Published
Biochemical characterization of MLH3 missense mutations does not reveal an apparent role of MLH3 in Lynch syndrome
Ou, J., Rasmussen, M., Westers, H., Andersen, S. D., Jager, P. O., Kooi, K. A., Niessen, R. C., Eggen, B. J. L., Nielsen, Finn Cilius, Kleibeuker, J. H., Sijmons, R. H., Rasmussen, Lene Juel & Hofstra, R. M. W., 2009, In: Genes, Chromosomes & Cancer. 48, 4, p. 340-50 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Prognostic value of periodic electroencephalographic discharges for neurological patients with profound disturbances of consciousness
Pedersen, G. L., Rasmussen, S., Gyllenborg, J., Benedek, Krisztina & Lauritzen, Martin, 2013, In: Clinical Neurophysiology. 124, 1, p. 44-51 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mitochondrial-Linked De Novo Pyrimidine Biosynthesis Dictates Human T-Cell Proliferation but Not Expression of Effector Molecules
Peeters, M. J. W., Aehnlich, P., Pizzella, A., Mølgaard, K., Seremet, T., Met, Özcan, Rasmussen, Lene Juel, thor Straten, P. & Desler, Claus, 2021, In: Frontiers in Immunology. 12, 718863.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
MERTK Acts as a costimulatory receptor on human cd8 t cells
Peeters, M. J. W., Dulkeviciute, D., Draghi, A., Ritter, C., Rahbech, A., Skadborg, S. K., Seremet, T., Simoes, A. M. C., Martinenaite, E., Halldorsdottir, H. R., Andersen, Mads Hald, Olofsson, G. H., Svane, Inge Marie, Rasmussen, Lene Juel, Met, Özcan, Becker, J. C., dqp123, dqp123, Desler, Claus & Straten, P. T., 2019, In: Cancer Immunology Research. 7, 9, p. 1472-1484 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Astrocytes gate synaptic transmission from unmyelinated sensory afferents
Perrier, Jean-Francois Marie, Christensen, R. K., Delgado-Lezama, R., Russo, R., Lind, Barbara Lykke, Alcocer, E. L., Fabbiani, G., Schmitt, Nicole, Lauritzen, Martin, Petersen, A. V. & Carlsen, E. M., Aug 2015, In: Glia. 63, S1, p. E241-E241 T08-22B .Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
Glucosamine but not iboprofen alters cartilage turnover in osteoarthritis patients in response to physical training
Petersen, S. G., Saxne, T., Heinegard, D., Hansen, M., Holm, L., Koskinen, S., Stordal, C., Christensen, H., Aagaard, P. & Kjær, Michael, 2010, In: Osteoarthritis and Cartilage. 18, 1, p. 34-40Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Functional examination of MLH1, MSH2, and MSH6 intronic mutations identified in Danish colorectal cancer patients
Petersen, S. M., Dandanell, M., Rasmussen, Lene Juel, Gerdes, Anne-Marie Axø, Krogh, L. N., Bernstein, I., Okkels, H., Wikman, F., Nielsen, Finn Cilius & Hansen, Thomas van Overeem, 2013, In: BMC Medical Genetics. 14, p. 103Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Exercise and NSAIDs: effect on muscle protein synthesis in patients with knee osteoarthritis
Petersen, S. G., Miller, B. F., Hansen, M., Kjær, Michael & Holm, L., 2011, In: Medicine and Science in Sports and Exercise. 43, 3, p. 425-31 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Protecting the Aging Genome
Petr, Michael Angelo, Tulika, T., Carmona Marin, Lina Maria & Scheibye-Knudsen, Morten, 2020, In: Trends in Cell Biology. 30, 2, p. 117-132 16 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
A cross-sectional study of functional and metabolic changes during aging through the lifespan in male mice
Petr, Michael Angelo, Alfaras, I., Krawcyzk, M., Bair, W. N., Mitchell, S. J., Morrell, C. H., Studenski, S. A., Price, N. L., Fishbein, K. W., Spencer, R. G., Scheibye-Knudsen, Morten, Lakatta, E. G., Ferrucci, L., Aon, M. A., Bernier, M. & de Cabo, R., 2021, In: eLife. 10, 25 p., e62952.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Approaches to diagnose DNA mismatch repair gene defects in cancer
Peña-Diaz, J. & Rasmussen, Lene Juel, Feb 2016, In: DNA Repair. 38, p. 147-154 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Neurovascular coupling in relation to cortical spreading depression
Piilgaard, H. & Lauritzen, Martin, 2014, In: Neuromethods. 88, p. 273-286 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The influence of training status on the drop in muscle strength after acute exercise
Pingel, Jessica, Moerch, L., Kjær, Michael & Langberg, Henning, 2009, In: Journal of Applied Physiology. 106, 4, p. 605-11 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
No inflammatory gene-expression response to acute exercise in human Achilles tendinopathy
Pingel, Jessica, Fredberg, U., Mikkelsen, L. R., Schjerling, Peter, Heinemeier, K. M., Kjær, Michael, Harrison, Adrian Paul & Langberg, Henning, 2013, In: European Journal of Applied Physiology. 113, 8, p. 2101-2109 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Local biochemical and morphological differences in human Achilles tendinopathy: a case control study
Pingel, Jessica, Fredberg, U., Qvortrup, Klaus, Larsen, J. O., Schjerling, Peter, Heinemeier, K. M., Kjær, Michael & Langberg, Henning, 2012, In: B M C Musculoskeletal Disorders. 13, 53, 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effects of transdermal estrogen on collagen turnover at rest and in response to exercise in postmenopausal women
Pingel, Jessica, Langberg, Henning, Skovgaard, D. C., Koskinen, S., Flyvbjerg, A., Frystyk, J., Kjær, Michael & Hansen, M., 2012, In: Journal of Applied Physiology. 113, 7, p. 1040-7 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
3-D ultrastructure and collagen composition of healthy and overloaded human tendon: evidence of tenocyte and matrix buckling
Pingel, Jessica, Lu, Y., Starborg, T., Fredberg, U., Langberg, Henning, Nedergaard, A., Weis, M., Eyre, D., Kjær, Michael & Kadler, K. E., 9 Feb 2014, In: Journal of Anatomy. 224, 5, p. 548–555 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Galectin-7 reprograms skin carcinogenesis by fostering innate immune evasive programs
Pinto, N. A., Abba, M. C., Laporte, L., Pérez Sáez, J. M., Blidner, A. G., Torres, N. I., Morales, R. M., Gatto, S. G., Bach, C. A., Veigas, F., García Rivello, H. J., Song, P., Frederiksen, J. H., Rasmussen, Lene Juel, Poirier, F., Croci, D. O., Sundblad, V., Rabinovich, G. A. & Cerliani, J. P., 2023, In: Cell Death and Differentiation. 30, p. pages906–921Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A novel TPR-BEN domain interaction mediates PICH-BEND3 association
Pitchai, G. P., Kaulich, M., Bizard, A. H., Mesa, Pablo, Yao, Q., Sarlos, K., Streicher, W. W., Nigg, E. A., Montoya, Guillermo & Hickson, Ian David, 2017, In: Nucleic Acids Research. 19, 2, p. 11413–11424Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Characterization of the NTPR and BD1 interacting domains of the human PICH-BEND3 complex
Pitchai, G. P., Hickson, Ian David, Streicher, W., Montoya, Guillermo & Mesa, Pablo, Aug 2016, In: Acta Crystallographica. Section F: Structural Biology and Crystallization Communications Online. 72, 8, p. 646-651 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
ATRX-Deficient High-Grade Glioma Cells Exhibit Increased Sensitivity to RTK and PDGFR Inhibitors
Pladevall Morera, David, Castejón-Griñán, M., Aguilera, P., Gaardahl, K., Ingham, Andreas, Brosnan-Cashman, J. A., Meeker, A. K. & Lopez-Contreras, Andres, 2022, In: Cancers. 14, 7, 1790.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Human RNF169 is a negative regulator of the ubiquitin-dependent response to DNA double-strand breaks
Poulsen, M., Lukas, C., Lukas, J., Bekker-Jensen, Simon Holst & Mailand, Niels, 2012, In: Journal of Cell Biology. 197, 2, p. 189-99 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
RNF111/Arkadia is a SUMO-targeted ubiquitin ligase that facilitates the DNA damage response
Poulsen, S. L., Hansen, R. K., Wagner, S. A., van Cuijk, L., van Belle, G. J., Streicher, W., Wikström, M., Choudhary, Chunaram, Houtsmuller, A. B., Marteijn, J. A., Bekker-Jensen, Simon Holst & Mailand, Niels, 10 Jun 2013, In: Journal of Cell Biology. 201, 6, p. 797-807 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Systems-wide analysis of ubiquitylation dynamics reveals a key role for PAF15 ubiquitylation in DNA-damage bypass
Povlsen, L. K., Beli, P., Wagner, S. A., Poulsen, S. L., Sylvestersen, K. B., Poulsen, J. W., Nielsen, Michael Lund, Bekker-Jensen, Simon Holst, Mailand, Niels & Choudhary, Chunaram, Oct 2012, In: Nature Cell Biology. 14, 10, p. 1089-98 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Unaltered lactate and glucose transporter levels in the MPTP mouse model of Parkinson's disease
Puchades, M., Sogn, C. J., Maehlen, J., Bergersen, L. H. & Gundersen, V., 1 Jan 2013, In: Journal of Parkinson's Disease. 3, 3, p. 371-85 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Influence of ornithine decarboxylase antizymes and antizyme inhibitors on agmatine uptake by mammalian cells
Ramos-Molina, B., Lopez-Contreras, Andres, Lambertos, A., Dardonville, C., Cremades, A. & Peñafiel, R., 2015, In: Amino Acids. 47, 5, p. 1025-34 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cognitive Change during the Life Course and Leukocyte Telomere Length in Late Middle-Aged Men
Rask, L., Bendix, L., Harbo, M., Fagerlund, Birgitte, Mortensen, Erik Lykke, Lauritzen, Martin & Osler, Merete, 9 Dec 2016, In: Frontiers in Aging Neuroscience. 8, 7 p., 300.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
DNA damage response, bioenergetics, and neurological disease: the challenge of maintaining brain health in an aging human population
Rasmussen, Lene Juel, Shiloh, Y., Bergersen, L. H., Sander, M., Bohr, Vilhelm & Tønjum, T., Oct 2013, In: Mechanisms of Ageing and Development. 134, 10, p. 427-33 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Pathological assessment of mismatch repair gene variants in Lynch syndrome: Past, present, and future
Rasmussen, Lene Juel, Heinen, C. D., Royer-Pokora, B., Drost, M., Tavtigian, S., Hofstra, R. M. W. & de Wind, N., Dec 2012, In: Human Mutation. 33, 12, p. 1617-25 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
EXO1 (Exonuclease 1)
Rasmussen, Lene Juel & Keijzers, G., 5 Jan 2017, Encyclopedia of Signaling Molecules . Choi, S. (ed.). New York: Springer, 7 p.Research output: Chapter in Book/Report/Conference proceeding › Encyclopedia chapter › Research
- Published
Response to: Design of a core classification process for DNA mismatch repair variations of a priori unknown functional significance
Rasmussen, Lene Juel, Heinen, C. D., Royer-Pokora, B., Drost, M., Tavtigian, S., Hofstra, R. M. W. & de Wind, N., Jun 2013, In: Human Mutation. 34, 6, p. 923-4 2 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Assessing Genetic Variants of Uncertain Significance: The Example of Lynch Syndrome
Rasmussen, Lene Juel & Heinen, C. D., 15 Apr 2014Research output: Other contribution › Net publication - Internet publication › Communication
- Published
Aging, longevity and health
Rasmussen, Lene Juel, Sander, M., Wewer, Ulla M. & Bohr, Vilhelm, 23 Jul 2011, In: Mechanisms of Ageing and Development. p. 522-32 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Modeling neuro-vascular coupling in rat cerebellum: characterization of deviations from linearity
Rasmussen, T., von Holstein-Rathlou, Niels-Henrik, Lauritzen, Martin, Rasmussen, T., Holstein-Rathlou, N. & Lauritzen, Martin, 1 Mar 2009, In: NeuroImage. 45, 1, p. 96-108 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Positive muscle protein net balance and differential regulation of atrogene expression after resistance exercise and milk protein supplementation
Reitelseder, S., Agergaard, J., Doessing, S., Helmark, I. C., Schjerling, Peter, van Hall, Gerrit, Kjær, Michael & Holm, L., 1 Feb 2014, In: European Journal of Nutrition. 53, 1, p. 321-33 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Potential biomarkers of DNA replication stress in cancer
Ren, L., Chen, L., Wu, Wei, Garribba, L., Tian, H., Liu, Z., Vogel, Ivan, Li, C., Hickson, Ian David & Liu, Ying, 2017, In: OncoTarget. 8, 23, p. 36996-37008 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
White matter lactate: Does it matter?
Rinholm, J. E. & Bergersen, L. H., 2014, In: Neuroscience. 276, p. 109-116 8 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Natural selection of mitochondria during somatic lifetime promotes healthy aging
Rodell, A., Rasmussen, Lene Juel, Bergersen, L. H., Singh, K. K. & Gjedde, Albert, 2013, In: Frontiers in Neuroenergetics. 5, p. 1-6 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Synthesis and SAR studies of 5-(pyridin-4-yl)-1,3,4-thiadiazol-2-amine derivatives as potent inhibitors of Bloom helicase
Rosenthal, A. S., Dexheimer, T. S., Gileadi, O., Nguyen, G. H., Chu, W. K., Hickson, Ian David, Jadhav, A., Simeonov, A. & Maloney, D. J., 15 Oct 2013, In: Bioorganic & Medicinal Chemistry Letters. 23, 20, p. 5660-6 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Characterising the proximal patellar tendon attachment and its relationship to skeletal maturity in adolescent ballet dancers
Rudavsky, A., Cook, J., Magnusson, Stig Peter, Kjær, Michael & Docking, S., Apr 2017, In: Muscles, Ligaments and Tendons Journal. 7, 2, p. 306-314 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Involvement of the DNA mismatch repair system in cisplatin sensitivity of testicular germ cell tumours
Rudolph, C., Melau, C., Nielsen, J. E., Jensen, K. V., Liu, D., Pena-Diaz, J., Meyts, E. R., Rasmussen, Lene Juel & Jorgensen, A., 2017, In: Cellular Oncology. 40, 4, p. 341-355Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic insights into biological mechanisms governing human ovarian ageing
Ruth, K. S., Day, F. R., Hussain, J., Martinez-Marchal, A., Aiken, C. E., Azad, A., Thompson, D. J., Knoblochova, L., Abe, H., Tarry-Adkins, J. L., Gonzalez, J. M., Fontanillas, P., Claringbould, A., Bakker, O. B., Sulem, P., Walters, R. G., Terao, C., Turon, S., Horikoshi, M., Lin, K. & 36 others, , 2021, In: Nature. 596, p. 393-397Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Differentially activated macrophages orchestrate myogenic precursor cell fate during human skeletal muscle regeneration
Saclier, M., Yacoub-Youssef, H., Mackey, Abigail, Arnold, L., Ardjoune, H., Magnan, M., Sailhan, F., Chelly, J., Pavlath, G. K., Mounier, R., Kjær, Michael & Chazaud, B., Feb 2013, In: Stem Cells. 31, 2, p. 384-96 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The challenges of human population ageing
Sander, M., Oxlund, Bjarke, Jespersen, Astrid Pernille, Krasnik, Allan, Mortensen, Erik Lykke, Westendorp, Rudi GJ & Rasmussen, Lene Juel, Mar 2015, In: Age and Ageing. 44, 2, p. 185-7 3 p.Research output: Contribution to journal › Journal article › Communication
- Published
H4K20me0 marks post-replicative chromatin and recruits the TONSL–MMS22L DNA repair complex
Saredi, G., Huang, H., Hammond, Colin, Alabert, C., Bekker-Jensen, Simon Holst, Forne, I., Reveron-Gomez, Nazaret, Foster, B. M., Mlejnkova, L., Bartke, T., Cejka, P., Mailand, Niels, Imhof, A., Patel, D. J. & Groth, Anja, 30 Jun 2016, In: Nature. 534, 7609, p. 714-8 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Life-long endurance exercise in humans: circulating levels of inflammatory markers and leg muscle size
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Activation of the ATR kinase by the RPA-binding protein ETAA1
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