- Published
LIFESTAT – Living with statins: An interdisciplinary project on the use of statins as a cholesterol-lowering treatment and for cardiovascular risk reduction
Christensen, Christa Lykke, Helge, Jørn Wulff, Krasnik, Allan, Kriegbaum, Margit, Rasmussen, Lene Juel, Hickson, Ian David, Liisberg, Kasper Bering, Oxlund, Bjarke, Bruun, B., Lau, Sofie Rosenlund, Olsen, M. N. A., Andersen, John Sahl, Heltberg, Andreas Søndergaard, Kuhlman, A. C. B., Morville, T. H., Dohlmann, T. L., Larsen, Steen & Dela, Flemming, 2016, In: Scandinavian Journal of Public Health. 44, 5, p. 534-539 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Spinal dorsal horn astrocytes release GABA in response to synaptic activation
Christensen, R. K., Delgado-Lezama, R., Russo, R. E., Lind, Barbara Lykke, Alcocer, E. L., Rath, Martin Fredensborg, Fabbiani, G., Schmitt, Nicole, Lauritzen, Martin, Petersen, A. V., Carlsen, Eva Maria Meier & Perrier, Jean-Francois Marie, 2018, In: The Journal of Physiology. 596, 20, p. 4983-4994 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
BLM has early and late functions in homologous recombination repair in mouse embryonic stem cells
Chu, W. K., Hanada, K., Kanaar, R. & Hickson, Ian David, 19 Aug 2010, In: Oncogene. 29, 33, p. 4705-14 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
RecQ helicases: multifunctional genome caretakers
Chu, W. K. & Hickson, Ian David, 2009, In: Nature Reviews. Cancer. 9, p. 644-654 11 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
FBH1 influences DNA replication fork stability and homologous recombination through ubiquitylation of RAD51
Chu, W. K., Payne, M. J., Beli, P., Hanada, K., Choudhary, C. & Hickson, Ian David, 2015, In: Nature Communications. 6, 7 p., 5931.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Preventing tendon overuse injuries
Cook, J., Kongsgaard, M., Kjær, Michael, Bahr, R. & Engebretsen, L., 2009, Sports Injury Prevention. Wiley-Blackwell, p. 187-196 9 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research
- Published
Vive la radiorésistance! Converging research in radiobiology and biogerontology to enhance human radioresistance for deep space exploration and colonization
Cortese, F., Klokov, D., Osipov, A., Stefaniak, J., Moskalev, A., Schastnaya, J., Cantor, C., Aliper, A., Mamoshina, P., Ushakov, I., Sapetsky, A., Vanhaelen, Q., Alchinova, I., Karganov, M., Kovalchuk, O., Wilkins, R., Shtemberg, A., Moreels, M., Baatout, S., Izumchenko, E. & 10 others, , 2018, In: OncoTarget. 9, 18, p. 14692-14722 31 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effects of Heavy Slow Resistance Training Combined With Corticosteroid Injections or Tendon Needling in Patients With Lateral Elbow Tendinopathy A 3-Arm Randomized Double-Blinded Placebo-Controlled Study
Couppé, Christian, Døssing, S., Bulow, P. M., Siersma, Volkert Dirk, Zilmer, C. K., Bang, C. W., Høffner, Rikke, Kracht, M., Hogg, P., Edstrom, G., Kjær, Michael & Magnusson, Stig Peter, 2022, In: American Journal of Sports Medicine. 50, 10, p. 2787-2796 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mechanical properties and collagen cross-linking of the patellar tendon in old and young men
Couppé, C., Hansen, P., Kongsgaard, M., Kovanen, V., Suetta, Charlotte, Aagaard, P., Kjær, Michael & Magnusson, Stig Peter, 2009, In: Journal of Applied Physiology. 107, 3, p. 880-6 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Quantification of cell density in rat Achilles tendon: development and application of a new method
Couppé, C., Svensson, R. B., Heinemeier, K. M., Thomsen, E. W., Bayer, M. L., Christensen, L., Kjær, Michael, Magnusson, Stig Peter & Schjerling, P., Jan 2017, In: Histochemistry and Cell Biology. 147, 1, p. 97-102 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Human Achilles tendon glycation and function in diabetes
Couppé, Christian, Svensson, R. B., Madsen, M. K., Kovanen, V., Grosset, J., Snorgaard, O., Bencke, J., Larsen, J. O., Bandholm, Thomas Quaade, Christensen, T. M., Boesen, A., Helmark, I. C., Aagaard, P., Kjær, Michael & Magnusson, Stig Peter, Jan 2016, In: Journal of Applied Physiology. 120, 2, p. 130-137 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Accuracy of MRI technique in measuring tendon cross-sectional area
Couppé, Christian, Svensson, R. B., Elbrønd (Bibs), Vibeke Sødring, Hansen, P., Kjær, Michael & Magnusson, Stig Peter, 2014, In: Clinical Physiology and Functional Imaging. 34, 3, p. 237-241 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Life-long endurance running is associated with reduced glycation and mechanical stress in connective tissue
Couppé, Christian, Svensson, R. B., Grosset, J., Kovanen, V., Nielsen, R. H., Olsen, M. R., Larsen, J. O., Praet, S. F. E., Skovgaard, D., Hansen, M., Aagaard, P., Kjær, Michael & Magnusson, Stig Peter, Aug 2014, In: Age (Dordrecht, Netherlands). 36, 4, p. 1-19 19 p., 9665.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Habitual side-specific loading leads to structural, mechanical, and compositional changes in the patellar tendon of young and senior lifelong male athletes
Couppé, Christian, Svensson, R. B., Skovlund, S. V., Jensen, Jacob Kildevang, Eriksen, C. S., Malmgaard-Clausen, N. M., Nybing, J. D., Kjær, Michael & Magnusson, Stig Peter, 2021, In: Journal of Applied Physiology. 131, 4, p. 1187-1199Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Senescent cells promote tissue NAD+ decline during ageing via the activation of CD38+ macrophages
Covarrubias, A. J., Kale, A., Perrone, R., Lopez-Dominguez, J. A., Pisco, A. O., Kasler, H. G., Schmidt, M. S., Heckenbach, I., Kwok, R., Wiley, C. D., Wong, H. S., Gibbs, E., Iyer, S. S., Basisty, N., Wu, Q., Kim, I. J., Silva, E., Vitangcol, K., Shin, K. O., Lee, Y. M. & 11 others, , 2020, In: Nature Metabolism. 2, 11, p. 1265-1283 19 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Modification of oxygen consumption and blood flow in mouse somatosensory cortex by cell-type-specific neuronal activity
Dahlqvist, M. K., Thomsen, Kirsten Joan, Postnov, D. D. & Lauritzen, Martin, 2020, In: Journal of Cerebral Blood Flow and Metabolism. 40, 10, p. 2010-2025 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Influence of Oral Contraceptive Use on Adaptations to Resistance Training
Dalgaard, L. B., Dalgas, U., Andersen, J. L., Rossen, N. B., Moller, A. B., Stodkilde-Jorgensen, H., Jorgensen, J. O., Kovanen, V., Couppe, C., Langberg, Henning, Kjær, Michael & Hansen, M., Jul 2019, In: Frontiers in Physiology. 10, 14 p., 824.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Ubiquitin Ligase XIAP Recruits LUBAC for NOD2 Signaling in Inflammation and Innate Immunity
Damgaard, R. B., Nachbur, U., Yabal, M., Wong, W. W., Fiil, Berthe Katrine, Kastirr, M., Rieser, E., Rickard, J. A., Bankovacki, A., Peschel, C., Ruland, J., Bekker-Jensen, Simon Holst, Mailand, Niels, Kaufmann, T., Strasser, A., Walczak, H., Silke, J., Jost, P. J. & Gyrd-Hansen, Mads, 2012, In: Molecular Cell. 46, 6, p. 746-58 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Disease-causing mutations in the XIAP BIR2 domain impair NOD2-dependent immune signalling
Damgaard, R. B., Fiil, Berthe Katrine, Speckmann, C., Yabal, M., Stadt, U. Z., Bekker-Jensen, Simon Holst, Jost, P. J., Ehl, S., Mailand, Niels & Gyrd-Hansen, Mads, 1 Jul 2013, In: E M B O Journal. 5, p. 1278-1295 18 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mass spectrometric analysis of lysine ubiquitylation reveals promiscuity at site level
Danielsen, J. M. R., Sylvestersen, K. B., Bekker-Jensen, Simon Holst, Szklarczyk, D., Poulsen, J. W., Horn, H., Jensen, Lars Juhl, Mailand, Niels & Nielsen, Michael Lund, 1 Mar 2011, In: Molecular and Cellular Proteomics. 10, 3, p. M110.003590Research output: Contribution to journal › Journal article › Research › peer-review
- Published
DNA damage-inducible SUMOylation of HERC2 promotes RNF8 binding via a novel SUMO-binding Zinc finger
Danielsen, J. M. R., Povlsen, L. K., Villumsen, B. H., Streicher, W., Nilsson, Jakob, Wikström, M., Bekker-Jensen, Simon Holst & Mailand, Niels, 2012, In: Journal of Cell Biology. 197, 2, p. 179-87 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Right-left asymmetry in corticospinal tract microstructure and dexterity are uncoupled in late adulthood
Demnitz, N., Madsen, K. S., Johnsen, L. K., Kjær, Michael, Boraxbekk, CJ & Siebner, Hartwig Roman, 2021, In: NeuroImage. 240, 118405.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Is it all in the baseline? Trajectories of chair stand performance over 4 years and their association with grey matter structure in older adults
Demnitz, N., Gates, A. T., Mortensen, Erik Lykke, Garde, Ellen, Wimmelmann, Cathrine Lawaetz, Siebner, Hartwig Roman, Kjær, Michael & Boraxbekk, CJ, 2023, In: Human Brain Mapping. 44, 11, p. 4299-4309 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The role of mitochondrial dysfunction in the progression of Alzheimer’s disease
Desler, Claus, Lillenes, M. S., Tønjum, T. & Rasmussen, Lene Juel, 2018, In: Current Medicinal Chemistry. 25, 40, p. 5578 - 5587Research output: Contribution to journal › Review › Research › peer-review
- Published
Partial inhibition of mitochondrial-linked pyrimidine synthesis increases tumorigenic potential and lysosome accumulation
Desler, Claus, Durhuus, J. A., Hansen, T. L. L., Anugula, Sharath, Zelander, N. T., Bøggild, S. & Rasmussen, Lene Juel, 2022, In: Mitochondrion. 64, p. 73-81 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
In Silico screening for functional candidates amongst hypothetical proteins
Desler, Claus, Suravajhala, P., Sanderhoff, M., Rasmussen, M. & Rasmussen, Lene Juel, 2009, In: BMC Bioinformatics. 10, p. 289Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Characterization of a highly conserved binding site of Mlh1 required for exonuclease I-dependent mismatch repair
Dherin, C., Gueneau, E., Francin, M., Nunez, M., Miron, S., Liberti, S. E., Rasmussen, Lene Juel, Zinn-Justin, S., Gilquin, B., Charbonnier, J. & Boiteux, S., 2009, In: Molecular and Cellular Biology. 29, 3, p. 907-18 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
RECQ5 Helicase Cooperates with MUS81 Endonuclease in Processing Stalled Replication Forks at Common Fragile Sites during Mitosis
Di Marco, S., Hasanova, Z., Kanagaraj, R., Chappidi, N., Altmannova, V., Menon, S., Sedlackova, H., Langhoff, J., Surendranath, K., Hühn, D., Bhowmick, Rahul, Marini, V., Ferrari, S., Hickson, Ian David, Krejci, L. & Janscak, P., 1 Jun 2017, In: Molecular Cell. 66, 5, p. 658-671.e8Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Skeletal muscle adaptation to immobilization and subsequent retraining in elderly men: No effect of anti-inflammatory medication
Dideriksen, K., Boesen, A. P., Kristiansen, J. F., Magnusson, Stig Peter, Schjerling, Peter, Holm, L. & Kjær, Michael, Sep 2016, In: Experimental Gerontology. 82, p. 8-18 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Tendon collagen synthesis declines with immobilization in elderly humans: no effect of anti-inflammatory medication
Dideriksen, K., Boesen, A. P., Reitelseder, S., Couppé, C., Svensson, R., Schjerling, P., Magnusson, Stig Peter, Holm, L. & Kjær, Michael, Feb 2017, In: Journal of Applied Physiology. 122, 2, p. 273-282 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Structural Analysis of a Complex between Small Ubiquitin-like Modifier 1 (SUMO1) and the ZZ Domain of CREB-binding Protein (CBP/p300) Reveals a New Interaction Surface on SUMO
Diehl, C., Akke, M., Bekker-Jensen, Simon Holst, Mailand, Niels, Streicher, W. & Wikström, M., 10 Jun 2016, In: Journal of Biological Chemistry. 291, 24, p. 12658-12672 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Histone displacement during nucleotide excision repair
Dinant, C., Bartek, J. & Bekker-Jensen, Simon Holst, 17 Oct 2012, In: International Journal of Molecular Sciences (Online). 13, 10, p. 13322-13337 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Rotation of Editorial Board Members and new publication formats
Dirnagl, U. & Lauritzen, Martin, 2011, In: Journal of Cerebral Blood Flow and Metabolism. 31, 7, p. 1501 1 p.Research output: Contribution to journal › Editorial › Research › peer-review
- Published
A new home for the Journal of Cerebral Blood Flow and Metabolism
Dirnagl, U. & Lauritzen, Martin, Feb 2016, In: Journal of Cerebral Blood Flow and Metabolism. 36, 2, p. 277Research output: Contribution to journal › Editorial › Research › peer-review
- Published
GH and IGF1 levels are positively associated with musculotendinous collagen expression: experiments in acromegalic and GH deficiency patients
Doessing, S., Holm, L., Heinemeier, K. M., Feldt-Rasmussen, Ulla, Schjerling, Peter, Qvortrup, Klaus, Larsen, J. O., Nielsen, R. H., Flyvbjerg, A. & Kjær, Michael, Dec 2010, In: European Journal of Endocrinology. 163, 6, p. 853-62 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Growth hormone stimulates the collagen synthesis in human tendon and skeletal muscle without affecting myofibrillar protein synthesis
Doessing, S., Heinemeier, K. M., Holm, L., Mackey, Abigail, Schjerling, Peter, Rennie, M., Petersen, K. S., Reitelseder, S., Kappelgaard, A., Rasmussen, M. H., Flyvbjerg, A. & Kjær, Michael, 15 Jan 2010, In: Journal of Physiology. 588, Pt 2, p. 341-51 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Functional implications of the p.Cys680Arg mutation in the MLH1 mismatch repair protein
Dominguez-Valentin, M., Drost, M., Therkildsen, C., Rambech, E., Ehrencrona, H., Angleys, M., Lau Hansen, T., de Wind, N., Nilbert, Mef Christina & Rasmussen, Lene Juel, Jul 2014, In: Molecular Genetics & Genomic Medicine. 2, 4, p. 352-355 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cortical spreading ischaemia is a novel process involved in ischaemic damage in patients with aneurysmal subarachnoid haemorrhage
Dreier, J. P., Major, S., Manning, A., Woitzik, J., Drenckhahn, C., Steinbrink, J., Tolias, C., Oliveira-Ferreira, A. I., Fabricius, M., Hartings, J. A., Vajkoczy, P., Lauritzen, M., Dirnagl, U., Bohner, G., Strong, A. J., COSBID study group, Dreier, J. P., Major, S., Manning, A., Woitzik, J. & 12 others, , 2009, In: Brain. 132, Pt 7, p. 1866-81 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Recording, analysis, and interpretation of spreading depolarizations in neurointensive care: Review and recommendations of the COSBID research group
Dreier, J. P., Fabricius, M., Ayata, C., Sakowitz, O. W., William Shuttleworth, C., Dohmen, C., Graf, R., Vajkoczy, P., Helbok, R., Suzuki, M., Schiefecker, A. J., Major, S., Winkler, M. K., Kang, E-J., Milakara, D., Oliveira-Ferreira, A. I., Reiffurth, C., Revankar, G. S., Sugimoto, K., Dengler, N. F. & 70 others, , May 2017, In: Journal of Cerebral Blood Flow and Metabolism. 37, 5, p. 1595-1625 31 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
A functional assay–based procedure to classify mismatch repair gene variants in Lynch syndrome
Drost, M., Tiersma, Y., Thompson, B. A., Frederiksen, J. H., Keijzers, G., Glubb, D., Kathe, S., Osinga, J., Westers, H., Pappas, L., Boucher, K. M., Molenkamp, S., Zonneveld, J. B., van Asperen, C. J., Goldgar, D. E., Wallace, S. S., Sijmons, R. H., Spurdle, A. B., Rasmussen, L. J., Greenblatt, M. S. & 2 others, , 2019, In: Genetics in Medicine. 21, p. 1486–1496Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic screens to identify pathogenic gene variants in the common cancer predisposition Lynch syndrome
Drost, M., Lützen, A., van Hees, S., Ferreira, D., Calléja, F., Zonneveld, J. B. M., Nielsen, Finn Cilius, Rasmussen, Lene Juel & de Wind, N., 4 Jun 2013, In: Proceedings of the National Academy of Science of the United States of America. 110, 23, p. 9403-8 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A rapid and cell-free assay to test the activity of lynch syndrome-associated MSH2 and MSH6 missense variants
Drost, M., Zonneveld, J. B. M., van Hees, S., Rasmussen, Lene Juel, Hofstra, R. M. W. & de Wind, N., 2012, In: Human Mutation. 33, 3, p. 488-94 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Genetic screens to identify pathogenic gene variants in the common cancer predisposition Lynch syndrome
Drost, M., Lützen, A., van Hees, S., Ferreira, D., Calléja, F., Zonneveld, J. B. M., Nielsen, Finn Cilius, Rasmussen, Lene Juel & de Wind, N., 2013, In: Proceedings of the National Academy of Sciences of the United States of America. 110, 23, p. 9403-9408 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Two integrated and highly predictive functional analysis-based procedures for the classification of MSH6 variants in Lynch syndrome
Drost, M., Tiersma, Y., Glubb, D., Kathe, S., van Hees, S., Calléja, F., Zonneveld, J. B. M., Boucher, K. M., Ramlal, R. P. E., Thompson, B. A., Rasmussen, Lene Juel, Greenblatt, M. S., Lee, A., Spurdle, A. B., Tavtigian, S. V. & de Wind, N., 2020, In: Genetics in Medicine. 22, p. 847–856Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Interaction between RECQL4 and OGG1 promotes repair of oxidative base lesion 8-oxoG and is regulated by SIRT1 deacetylase
Duan, S., Han, X., Akbari, M., Croteau, D. L., Rasmussen, Lene Juel & Bohr, Vilhelm, 2020, In: Nucleic Acids Research. 48, 12, p. 6530–6546Research output: Contribution to journal › Journal article › Research › peer-review
- Published
EX-vivo whole blood stimulation with A2E does not elicit an inflammatory cytokine response in patients with age-related macular degeneration
Durhuus, J. A., Rozing, Maarten Pieter, Nielsen, M. K., Molbech, C. R., Keijzers, G., Scheibye-Knudsen, Morten, Rasmussen, Lene Juel, Westendorp, Rudi GJ & Sørensen, Torben Lykke, 2021, In: Scientific Reports. 11, 1, 8226.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Simvastatin improves mitochondrial respiration in peripheral blood cells
Durhuus, J. A., Hansson, Svenja, Morville, T., Kuhlman, A. B., Dohlmann, T. L., Larsen, Steen, Helge, Jørn Wulff, Angleys, M., Muniesa-Vargas, A., Bundgaard, J. R., Hickson, Ian David, Dela, Flemming, Desler, Claus & Rasmussen, Lene Juel, 2020, In: Scientific Reports. 10, 1, 17012.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mitochondria in health and disease: 3rd annual conference of society for mitochondrial research and medicine - 19-20 december 2013 - bengaluru, India
Durhuus, J. A., Desler, Claus & Rasmussen, Lene Juel, Jan 2015, In: Mitochondrion. 20, p. 7-12 6 p.Research output: Contribution to journal › Conference article › Research › peer-review
- Published
Effects of age on muscle power, postural control and functional capacity after short-term immobilization and retraining
Elam, C., Hvid, L. G., Christensen, U., Kjær, Michael, Magnusson, Stig Peter, Aagaard, P., Bunketorp Käll, L. & Suetta, Charlotte, 2022, In: Journal of Musculoskeletal Neuronal Interactions. 22, 4, p. 486-497 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The Ruptured Achilles Tendon Elongates for 6 Months After Surgical Repair Regardless of Early or Late Weightbearing in Combination With Ankle Mobilization: A Randomized Clinical Trial
Eliasson, P., Agergaard, A., Couppe, C., Svensson, R., Hoeffner, R., Warming, S., Warming, N., Holm, C., Jensen, M. H., Krogsgaard, Michael R., Kjær, Michael & Magnusson, Stig Peter, 2018, In: American Journal of Sports Medicine. 46, 10, p. 2492-2502Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Simvastatin and atorvastatin reduce the mechanical properties of tendon constructs in vitro and introduce catabolic changes in the gene expression pattern
Eliasson, P., Svensson, R. B., Giannopoulos, A., Eismark, C., Kjær, Michael, Schjerling, P. & Heinemeier, K. M., 2017, In: PLOS ONE. 12, 3, 16 p., e0172797.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Ruptured human Achilles tendon has elevated metabolic activity up to 1 year after repair
Eliasson, P., Couppé, C., Lonsdale, M., Svensson, R. B., Neergaard, C., Kjær, Michael, Friberg, L. & Magnusson, Stig Peter, Sep 2016, In: European Journal of Nuclear Medicine and Molecular Imaging. 43, 10, p. 1868-77 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The effect of 4 months exercise training on systemic biomarkers of cartilage and bone turnover in hip osteoarthritis patients
Ellegaard, M., Bieler, T., Beyer, N., Kjær, Michael & Jørgensen, Niklas Rye, 2020, In: Translational Sports Medicine. 3, 1, p. 16-25Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Pathway-specific variations in neurovascular and neurometabolic coupling in rat primary somatosensory cortex
Enager, P., Hansen, H. P., Offenhauser, N., Kocharyan, A., Fernandes, P., Hamel, E. & Lauritzen, Martin, 1 May 2009, In: Journal of Cerebral Blood Flow and Metabolism. 29, 5, p. 976-86 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The response of mammalian cells to UV-light reveals Rad54-dependent and independent pathways of homologous recombination
Eppink, B., Tafel, A. A., Hanada, K., van Drunen, E., Hickson, Ian David, Essers, J. & Kanaar, R., Nov 2011, In: D N A Repair. 10, 11, p. 1095-105 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Physical activity as intervention for age-related loss of muscle mass and function: protocol for a randomised controlled trial (the LISA study)
Eriksen, C. S., Garde, Ellen, Reislev, N. L., Wimmelmann, Cathrine Lawaetz, Bieler, T., Ziegler, A. K., Gylling, A. T., Dideriksen, K. J., Siebner, Hartwig Roman, Mortensen, Erik Lykke & Kjær, Michael, Dec 2016, In: B M J Open. 6, 12, p. 1-13 13 p., e012951.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Lower tendon stiffness in very old compared with old individuals is unaffected by short-term resistance training of skeletal muscle
Eriksen, C. S., Henkel, C., Svensson, R. B., Agergaard, A., Couppé, C., Kjær, Michael & Magnusson, Stig Peter, 2018, In: Journal of Applied Physiology. 125, 1, p. 205-214 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
From powerhouse to perpetrator—mitochondria in health and disease
Fakouri, N. B., Hansen, T. L., Desler, Claus, Anugula, Sharath & Rasmussen, Lene Juel, 2019, In: Biology. 8, 2, 15 p., 35.Research output: Contribution to journal › Review › Research › peer-review
- Published
Rev1 contributes to proper mitochondrial function via the PARP-NAD(+)-SIRT1-PGC1 alpha axis
Fakouri, N. B., Durhuus, J. A., Regnell, C. E., Angleys, M., Desler, Claus, Hasan-Olive, M., Martin-Pardillos, A., Tsaalbi-Shtylik, A., Thomsen, Kirsten Joan, Lauritzen, Martin, Bohr, Vilhelm, de Wind, N., Bergersen, L. H. & Rasmussen, Lene Juel, 2017, In: Scientific Reports. 7, 14 p., 12480.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
NAD(+) Replenishment Improves Lifespan and Healthspan in Ataxia Telangiectasia Models via Mitophagy and DNA Repair
Fang, E. F., Kassahun, H., Croteau, D. L., Scheibye-Knudsen, M., Marosi, K., Lu, H., Shamanna, R. A., Kalyanasundaram, S., Bollineni, R. C., Wilson, M. A., Iser, W. B., Wollman, B. N., Morevati, M., Li, J., Kerr, J. S., Lu, Q., Waltz, T. B., Tian, J., Sinclair, D. A., Mattson, M. P. & 2 others, , 11 Oct 2016, In: Cell Metabolism. 24, 4, p. 566-581 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Tomatidine enhances lifespan and healthspan in C. elegans through mitophagy induction via the SKN-1/Nrf2 pathway
Fang, E. F., Waltz, T. B., Kassahun, H., Lu, Q., Kerr, J. S., Morevati, M., Fivenson, E. M., Wollman, B. N., Marosi, K., Wilson, M. A., Iser, W. B., Eckley, D. M., Zhang, Y., Lehrmann, E., Goldberg, I. G., Scheibye-Knudsen, Morten, Mattson, M. P., Nilsen, H., Bohr, Vilhelm & Becker, K. G., 2017, In: Scientific Reports. 7, 46208.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Interventions for age-related diseases: Shifting the paradigm
Figueira, I., Fernandes, A., Mladenovic Djordjevic, A., Lopez-Contreras, Andres, Henriques, C. M., Selman, C., Ferreiro, E., Gonos, E. S., Trejo, J. L., Misra, J., Rasmussen, Lene Juel, Xapelli, S., Ellam, T. & Bellantuono, I., Dec 2016, In: Mechanisms of Ageing and Development. 160, p. 69-92 24 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
OTULIN Restricts Met1-Linked Ubiquitination to Control Innate Immune Signaling
Fiil, Berthe Katrine, Damgaard, R. B., Wagner, S. A., Keusekotten, K., Fritsch, M., Bekker-Jensen, Simon Holst, Mailand, Niels, Choudhary, Chunaram, Komander, D. & Gyrd-Hansen, Mads, 27 Jun 2013, In: Molecular Cell. 50, 6, p. 818-30 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mitophagy in neurodegeneration and aging
Fivenson, E. M., Lautrup, S., Sun, N., Scheibye-Knudsen, Morten, Stevnsner, T., Nilsen, H., Bohr, Vilhelm & Fang, E. F., 2017, In: Neurochemistry International. 109, p. 202-209Research output: Contribution to journal › Review › Research › peer-review
- Published
Increased 20-HETE synthesis explains reduced cerebral blood flow but not impaired neurovascular coupling after cortical spreading depression in rat cerebral cortex: 20-HETE synthesis explains reduced CBF after CSD
Fordsmann, J. C., ko, R., Choi, H. B., Thomsen, Kirsten Joan, Witgen, B. M., Mathiesen, C., Lønstrup, M., Hansen, H. P., MacVicar, B. A. & Lauritzen, Martin, Feb 2013, In: Journal of Neuroscience. p. 2562-2570 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Spontaneous astrocytic Ca2+ activity abounds in electrically suppressed ischemic penumbra of aged mice
Fordsmann, J. C., Murmu, R. P., Cai, Changsi, Brazhe, A., Thomsen, Kirsten Joan, Zambach, S. A., wbh615, wbh615, Lind, Barbara Lykke & Lauritzen, Martin, 2019, In: Glia. 67, 1, p. 37-52 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
FBH1 co-operates with MUS81 in inducing DNA double-strand breaks and cell death following replication stress
Fugger, K., Chu, W. K., Haahr, P., Kousholt, A. N., Beck, H., Payne, M. J., Hanada, K., Hickson, Ian David & Sørensen, Claus Storgaard, 2013, In: Nature Communications. 4, p. 1423Research output: Contribution to journal › Journal article › Research › peer-review
- Published
FBH1 Catalyzes Regression of Stalled Replication Forks
Fugger, K., Mistrik, M., Neelsen, K. J., Yao, Q., Zellweger, R., Kousholt, A. N., Haahr, Peter Thorlund, Chu, W. K., Bartek, J., Lopes, M., Hickson, Ian David & Sørensen, Claus Storgaard, 10 Mar 2015, In: Cell Reports.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Folate stress induces SLX1- and RAD51-dependent mitotic DNA synthesis at the fragile X locus in human cells
Garribba, L., Bjerregaard, Victoria Alexandra, Gonçalves Dinis, M. M., Özer, Ö., Wu, Wei, Sakellariou, D., Pena-Diaz, J., Hickson, Ian David & Liu, Ying, 2020, In: Proceedings of the National Academy of Sciences of the United States of America. 117, 28, p. 16527-16536 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Inducing and Detecting Mitotic DNA Synthesis at Difficult-to-Replicate Loci
Garribba, L., Wu, Wei, Özer, Ö., Bhowmick, Rahul, Hickson, Ian David & Liu, Ying, 2018, Methods in Enzymology: Mechanisms of DNA Recombination and Genome Rearrangements: Intersection between Homologous Recombination, DNA Replication and DNA Repair. Spies, M. & Malkova, A. (eds.). Elsevier, Vol. 601. p. 45-58 14 p. (Methods in Enzymology; No. 601).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
PICH Supports Embryonic Hematopoiesis by Suppressing a cGAS-STING-Mediated Interferon Response
Geng, X., Zhang, C., Li, M., Wang, J., Ji, F., Feng, H., Xing, M., Li, F., Zhang, L., Li, W., Chen, Z., Hickson, Ian David, Shen, H. & Ying, S., 2022, In: Advanced Science. 9, 7, 2103837.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Rad54 and Mus81 cooperation promotes DNA damage repair and restrains chromosome missegregation
Ghamrasni, S. E., Cardoso, R., Li, L., Guturi, K. K. N., Bjerregaard, Victoria Alexandra, Liu, Ying, Venkatesan, S., Hande, M. P., Henderson, J. T., Sanchez, O., Hickson, Ian David, Hakem, A. & Hakem, R., 15 Sep 2016, In: Oncogene. 35, 37, p. 4836-4845 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cellular homeostatic tension and force transmission measured in human engineered tendon
Giannopoulos, A., Svensson, R. B., Heinemeier, K. M., Schjerling, P., Kadler, K. E., Holmes, D. F., Kjær, Michael & Magnusson, Stig Peter, 2018, In: Journal of Biomechanics. 78, p. 161-165 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Ubiquitin-SUMO Circuitry Controls Activated Fanconi Anemia ID Complex Dosage in Response to DNA Damage
Gibbs-Seymour, I., Oka, Y., Rajendra, E., Weinert, B. T., Passmore, L. A., Patel, K. J., Olsen, Jesper Velgaard, Choudhary, Chunaram, Bekker-Jensen, Simon Holst & Mailand, Niels, Jan 2015, In: Molecular Cell. 57, 1, p. 150-64 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Lamin A/C-dependent interaction with 53BP1 promotes cellular responses to DNA damage
Gibbs-Seymour, I., Markiewicz, E., Bekker-Jensen, Simon Holst, Mailand, Niels & Hutchison, C. J., Apr 2015, In: Aging Cell. 14, 2, p. 162-9 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The hallmarks of aging
Gilmour, B. C., Bergersen, L. H. & Fang, E. F., 2022, Molecular, Cellular, and Metabolic Fundamentals of Human Aging. Academic Press, p. 1-6 6 p.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
Growth Hormone Receptor Antagonist Treatment Reduces Exercise Performance in Young Males
Goto, K., Doessing, S., Nielsen, R. H., Flyvbjerg, A. & Kjær, Michael, 2009, In: Journal of Clinical Endocrinology and Metabolism. 94, 9, p. 3265-3272 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A Role for BLM in Double-Strand Break Repair Pathway Choice: Prevention of CtIP/Mre11-Mediated Alternative Nonhomologous End-Joining.
Grabarz, A., Guirouilh-Barbat, J., Barascu, A., Pennarun, G., Genet, D., Rass, E., Germann, S. M., Bertrand, P., Hickson, Ian David & Lopez, B. S., 17 Oct 2013, In: Cell Reports. 5, 1, p. 21-28 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
TRIP12 and UBR5 Suppress Spreading of Chromatin Ubiquitylation at Damaged Chromosomes
Gudjónsson, Thorkell, Altmeyer, M. F., Savic, V., Toledo Lazaro, L. I., Dinant, C., Grøfte, M., Bartkova, J., Poulsen, M., Oka, Y., Bekker-Jensen, Simon Holst, Mailand, Niels, Neumann, B., Heriche, J., Shearer, R., Saunders, D., Bartek, J., Lukas, Jiri & Lukas, Claudia, 17 Aug 2012, In: Cell. 150, 4, p. 697-709 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Systems modelling predicts chronic inflammation and genomic instability prevent effective mitochondrial regulation during biological ageing
Guimera, A. M., Clark, P., Wordsworth, J., Anugula, Sharath, Rasmussen, Lene Juel & Shanley, D. P., 2022, In: Experimental Gerontology. 166, 9 p., 111889.Research output: Contribution to journal › Review › Research › peer-review
- Published
Neuroglial Transmission
Gundersen, V., Storm-Mathisen, J. & Bergersen, L. H., Jul 2015, In: Physiological Reviews. 95, 3, p. 695-726 32 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The influence of prolonged strength training upon muscle and fat in healthy and chronically diseased older adults
Gylling, A. T., Eriksen, C. S., Garde, Ellen, Wimmelmann, Cathrine Lawaetz, Reislev, N. L., Bieler, T., Ziegler, A. K., Andersen, K. W., Bauer, C., Dideriksen, K., Bækgaard, M., Mertz, K. H., Bayer, M. L., Bloch-Ibenfeldt, M., Boraxbekk, CJ, Siebner, Hartwig Roman, Mortensen, Erik Lykke & Kjær, Michael, 2020, In: Experimental Gerontology. 136, 110939.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Maintenance of muscle strength following a one-year resistance training program in older adults
Gylling, A. T., Bloch-Ibenfeldt, M., Eriksen, C. S., Ziegler, A. K., Wimmelmann, Cathrine Lawaetz, Bækgaard, M., Boraxbekk, CJ, Siebner, Hartwig Roman, Mortensen, Erik Lykke & Kjær, Michael, 2020, In: Experimental Gerontology. 139, 111049.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Activation of the ATR kinase by the RPA-binding protein ETAA1
Haahr, Peter Thorlund, Hoffmann, Saskia, Tollenaere, M. A. X., Ho, T., Toledo Lazaro, L. I., Mann, Matthias, Bekker-Jensen, Simon Holst, Räschle, M. & Mailand, Niels, Nov 2016, In: Nature Cell Biology. 18, 11, p. 1196–1207Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Capillary pericytes regulate cerebral blood flow in health and disease
Hall, C. N., Reynell, C., Gesslein, B., Hamilton, N. B., Mishra, A., Sutherland, B. A., O'Farrell, F. M., Buchan, A. M., Lauritzen, Martin & Attwell, D., Apr 2014, In: Nature. 508, 7494, p. 55-60 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Basic Components of Connective Tissues and Extracellular Matrix: Elastin, Fibrillin, Fibulins, Fibrinogen, Fibronectin, Laminin, Tenascins and Thrombospondins
Halper, J. & Kjær, Michael, 2014, Progress in Heritable Soft Connective Tissue Diseases. Vol. 802. p. 31-47 17 p. (Advances in Experimental Medicine and Biology).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
Cyclosporine A, FK506, and NIM811 ameliorate prolonged CBF reduction and impaired neurovascular coupling after cortical spreading depression
Hansen, H. P., Witgen, B. M., Rasmussen, P. & Lauritzen, Martin, 2011, In: Journal of Cerebral Blood Flow and Metabolism. 31, 7, p. 1588-98 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Persistent increase in oxygen consumption and impaired neurovascular coupling after spreading depression in rat neocortex
Hansen, H. P. & Lauritzen, Martin, 1 Sep 2009, In: Journal of Cerebral Blood Flow and Metabolism. 29, 9, p. 1517-27 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effect of administration of oral contraceptives in vivo on collagen synthesis in tendon and muscle connective tissue in young women
Hansen, M., Miller, B. F., Holm, L., Doessing, S., Petersen, S. G., Skovgaard, D., Frystyk, J., Flyvbjerg, A., Koskinen, S., Pingel, Jessica, Kjær, Michael & Langberg, Henning, 2009, In: Journal of Applied Physiology. 106, 4, p. 1435-43 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Influence of Sex and Estrogen on Musculotendinous Protein Turnover at Rest and After Exercise
Hansen, M. & Kjær, Michael, 2014, In: Exercise and Sport Sciences Reviews. 42, 4, p. 183–192 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effect of estrogen on tendon collagen synthesis, tendon structural characteristics, and biomechanical properties in postmenopausal women
Hansen, M., Kongsgaard, M., Holm, L., Skovgaard, D., Magnusson, Stig Peter, Qvortrup, Klaus, Larsen, J. O., Dahl, M., Serup, A., Frystyk, J., Flyvbjerg, A., Langberg, Henning & Kjær, Michael, 2009, In: Journal of Applied Physiology. 106, 4, p. 1385-93 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Sex Hormones and Tendon
Hansen, M. & Kjær, Michael, Aug 2016, Metabolic influences on risk for tendon disorders. Springer, Vol. 920. p. 139-149 11 p. (Advances in Experimental Medicine and Biology).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
Impact of oral contraceptive use and menstrual phases on patellar tendon morphology, biochemical composition and biomechanical properties in female athletes
Hansen, M. D., Couppé, Christian, Hansen, C., Skovgaard, D., Kovanen, V., Larsen, J. O., Aagaard, P., Magnusson, Stig Peter & Kjær, Michael, 21 Feb 2013, In: Journal of Applied Physiology. 114, p. 998-1008 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Subclinical cognitive decline in middle-age is associated with reduced task-induced deactivation of the brain's default mode network
Hansen, N. L., Lauritzen, Martin, Mortensen, Erik Lykke, Osler, Merete, Avlund, K., Fagerlund, Birgitte & Rostrup, E., Sep 2014, In: Human Brain Mapping. 35, 9, p. 4488-98 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glutaraldehyde Cross-Linking of TendonMechanical Effects at the Level of the Tendon Fascicle and Fibril
Hansen, P., Svensson, R. B., Aagaard, P., Trappe, T., Haraldsson, B. T., Kjær, Michael, Magnusson, P. & Hassenkam, Tue, 2009, In: Connective Tissue Research. 50, 4, p. 211-222 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glutaraldehyde cross-linking of tendon mechanical effects at the level of the tendon fascicle and fibril
Hansen, P., Hassenkam, Tue, Svensson, R. B., Aagaard, P., Trappe, T., Haraldsson, B. T., Kjær, Michael & Magnusson, P., 2009, In: Connective Tissue Research. 50, 4, p. 211-22 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Lower strength of the human posterior patellar tendon seems unrelated to mature collagen cross-linking and fibril morphology
Hansen, P., Haraldsson, B. T., Aagaard, P., Kovanen, V., Avery, N. C., Qvortrup, Klaus, Larsen, J. O., Krogsgaard, M., Kjær, Michael, Magnusson, Stig Peter, Hansen, P., Haraldsson, B. T., Aagaard, P., Kovanen, V., Avery, N. C., Qvortrup, K., Larsen, J. O., Krogsgaard, Michael R., Kjær, Michael & Magnusson, Stig Peter, 1 Jan 2010, In: Journal of Applied Physiology. 108, 1, p. 47-52 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
SCAI promotes DNA double-strand break repair in distinct chromosomal contexts
Hansen, R. K., Mund, A., Poulsen, S. L., Sandoval, M., Klement, K., Tsouroula, K., Tollenaere, M. A. X., Räschle, M., Soria, R., Offermanns, S., Worzfeld, T., Grosse, R., Brandt, D. T., Rozell, B., Mann, M., Cole, F., Soutoglou, E., Goodarzi, A. A., Daniel, J. A., Mailand, N. & 1 others, , 7 Nov 2016, In: Nature Cell Biology. 18, 12, p. 1357–1366Research output: Contribution to journal › Letter › Research › peer-review
- Published
Is There a Link between Mitochondrial Reserve Respiratory Capacity and Aging?
Hansen, T. L., Rasmussen, Lene Juel, Desler, Claus, Frederiksen, J. B., Espersen, M. L. M. & Singh, K. K., 2012, In: Journal of Aging Research. 2012, p. 192503 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Corticosteroid administration alters the mechanical properties of isolated collagen fascicles in rat-tail tendon
Haraldsson, B. T., Aagaard, P., Crafoord-Larsen, D., Kjær, Michael & Magnusson, Stig Peter, 2009, In: Scandinavian Journal of Medicine & Science in Sports Online. 19, 5, p. 621-6 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Life-long endurance exercise in humans: circulating levels of inflammatory markers and leg muscle size
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Activation of the ATR kinase by the RPA-binding protein ETAA1
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Is There a Link between Mitochondrial Reserve Respiratory Capacity and Aging?
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Protocol for the combined cardiometabolic deep phenotyping and registry-based 20-year follow-up study of the Inter99 cohort
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Muscle fascicle and sarcomere adaptation in response to Achilles tendon elongation in an animal model
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