- 2016
- Published
Effects of Sex, Strain, and Energy Intake on Hallmarks of Aging in Mice
Mitchell, S. J., Madrigal-Matute, J., Scheibye-Knudsen, M., Fang, E., Aon, M., Gonzalez-Reyes, J. A., Cortassa, S., Kaushik, S., Gonzalez-Freire, M., Patel, B., Wahl, D., Ali, A., Calvo-Rubio, M., Buron, M. I., Guiterrez, V., Ward, T. M., Palacios, H. H., Cai, H., Frederick, D. W., Hine, C. & 27 others, , 14 Jun 2016, In: Cell Metabolism. 23, 6, p. 1093-1112Research output: Contribution to journal › Journal article › Research › peer-review
- Published
PICH promotes mitotic chromosome segregation: Identification of a novel role in rDNA disjunction
Nielsen, Christian Friberg & Hickson, Ian David, 17 Oct 2016, In: Cell Cycle. 15, 20, p. 2704-2711 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Efficacy of ATR inhibitors as single agents in Ewing sarcoma
Nieto-Soler, M., Morgado-Palacin, I., Lafarga, V., Lecona, E., Murga, M., Callen, E., Azorin, D., Alonso, J., Lopez-Contreras, Andres, Nussenzweig, A. & Fernandez-Capetillo, O., 26 Aug 2016, In: OncoTarget. 7, 37, p. 58759-58767Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Acquired Localized Cutis Laxa due to Increased Elastin Turnover
Nygaard, R. H., Maynard, S., Schjerling, P., Kjær, M., Qvortrup, Klaus, Bohr, Vilhelm, Rasmussen, Lene Juel, Jemec, Gregor & Heidenheim, M., 14 Jun 2016, In: Case Reports in Dermatology. 8, 1, p. 42-51 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Approaches to diagnose DNA mismatch repair gene defects in cancer
Peña-Diaz, J. & Rasmussen, Lene Juel, Feb 2016, In: DNA Repair. 38, p. 147-154 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Characterization of the NTPR and BD1 interacting domains of the human PICH-BEND3 complex
Pitchai, G. P., Hickson, Ian David, Streicher, W., Montoya, Guillermo & Mesa, Pablo, Aug 2016, In: Acta Crystallographica. Section F: Structural Biology and Crystallization Communications Online. 72, 8, p. 646-651 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cognitive Change during the Life Course and Leukocyte Telomere Length in Late Middle-Aged Men
Rask, L., Bendix, L., Harbo, M., Fagerlund, Birgitte, Mortensen, Erik Lykke, Lauritzen, Martin & Osler, Merete, 9 Dec 2016, In: Frontiers in Aging Neuroscience. 8, 7 p., 300.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
H4K20me0 marks post-replicative chromatin and recruits the TONSL–MMS22L DNA repair complex
Saredi, G., Huang, H., Hammond, Colin, Alabert, C., Bekker-Jensen, Simon Holst, Forne, I., Reveron-Gomez, Nazaret, Foster, B. M., Mlejnkova, L., Bartke, T., Cejka, P., Mailand, Niels, Imhof, A., Patel, D. J. & Groth, Anja, 30 Jun 2016, In: Nature. 534, 7609, p. 714-8 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cockayne syndrome group A and B proteins converge on transcription-linked resolution of non-B DNA
Scheibye-Knudsen, M., Tseng, A., Jensen, M. B., Scheibye-Alsing, K., Fang, E. F., Iyama, T., Bharti, S. K., Marosi, K., Froetscher, L., Kassahun, H., Eckley, D. M., Maul, R. W., Bastian, P., De, S., Ghosh, S., Nilsen, H., Goldberg, I. G., Mattson, M. P., Wilson, D. M. . III., Brosh, R. M. . J. & 2 others, , 1 Nov 2016, In: National Academy of Sciences. Proceedings. 113, 44, p. 12502-12507Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Neurodegeneration in Accelerated Aging
Scheibye-Knudsen, Morten, Nov 2016, In: Danish Medical Journal. 63, 11, 21 p., B5308.Research output: Contribution to journal › Review › Research › peer-review
- Published
Neurodegeneration in accelerated aging
Scheibye-Knudsen, Morten, 2016, 190 p.Research output: Book/Report › Doctoral thesis › Research
- Published
Regulation of DNA double-strand break repair by ubiquitin and ubiquitin-like modifiers
Schwertman, P., Bekker-Jensen, Simon Holst & Mailand, Niels, Jun 2016, In: Nature Reviews. Molecular Cell Biology. 17, 6, p. 379-94 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glia-Neuron Interactions in the Retina Can Be Studied in Cocultures of Muller Cells and Retinal Ganglion Cells
Jensen, Dorte Skytt, Toft-Kehler, A. K., Braendstrup, C. T., Cejvanovic, S., Gurubaran, I. S., Bergersen, L. H. & Kolko, Miriam, 2016, In: Journal of Biomedicine and Biotechnology. 2016, 11 p., 1087647.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effect of aging and exercise on the tendon
Svensson, R. B., Heinemeier, K. M., Couppé, Christian, Kjær, Michael & Magnusson, Stig Peter, 1 Dec 2016, In: Journal of Applied Physiology. 121, 6, p. 1237-1246 10 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
A Novel Rrm3 Function in Restricting DNA Replication via an Orc5-Binding Domain Is Genetically Separable from Rrm3 Function as an ATPase/Helicase in Facilitating Fork Progression
Syed, S., Desler, Claus, Rasmussen, Lene Juel & Schmidt, K. H., Dec 2016, In: P L o S Genetics. 12, 12, 28 p., e1006451.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Elevated p16ink4a Expression in Human Labial Salivary Glands as a Potential Correlate of Cognitive Aging in Late Midlife
Sørensen, Christiane Elisabeth, Tritsaris, Katerina, Reibel, Jesper, Lauritzen, Martin, Mortensen, Erik Lykke, Osler, Merete & Pedersen, Anne Marie Lynge, 2016, In: PloS one. 11, 3, p. e0152612Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Early detection of Alzheimer's disease using MRI hippocampal texture
Sørensen, L., Igel, Christian, Hansen, N. L., Osler, Merete, Lauritzen, Martin, Rostrup, Egill & Nielsen, Mads, 2016, In: Human Brain Mapping. 37, 3, p. 1148-1161 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Oxidative Stress-Induced Dysfunction of Muller Cells During Starvation
Toft-Kehler, A. K., Gurubaran, I. S., Desler, Claus, Rasmussen, Lene Juel, Jensen, Dorte Skytt & Kolko, Miriam, May 2016, In: Investigative Ophthalmology & Visual Science. 57, 6, p. 2721-2728Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Melatonin and cortisol profiles in late midlife and their association with age-related changes in cognition
Waller, K. L., Mortensen, Erik Lykke, Avlund, K., Fagerlund, Birgitte, Lauritzen, Martin, Gammeltoft, S. & Jennum, Poul, 2016, In: Nature and Science of Sleep. 8, p. 47-53 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Subjective sleep quality and daytime sleepiness in late midlife and their association with age-related changes in cognition
Waller, K. L., Mortensen, Erik Lykke, Avlund, K., Osler, Merete, Fagerlund, Birgitte, Lauritzen, Martin & Jennum, Poul, Jan 2016, In: Sleep Medicine. 17, p. 165-73 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2015
- Published
Spreading Depression, Spreading Depolarizations, and the Cerebral Vasculature
Ayata, C. & Lauritzen, Martin, Jul 2015, In: Physiological Reviews. 95, 3, p. 953-993 41 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
RNF138 joins the HR team
Bekker-Jensen, Simon Holst & Mailand, Niels, Oct 2015, In: Nature Cell Biology. 17, 11, p. 1375-7 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Lactate transport and signaling in the brain: Potential therapeutic targets and roles in body-brain interaction
Bergersen, L. H., Feb 2015, In: Journal of Cerebral Blood Flow and Metabolism. 35, 2, p. 176-185 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Heavy Slow Resistance Versus Eccentric Training as Treatment for Achilles Tendinopathy: A Randomized Controlled Trial
Beyer, R., Kongsgaard, M., Hougs Kjær, B., Øhlenschlæger, Tommy Frisgaard, Kjær, Michael & Magnusson, Stig Peter, Jul 2015, In: American Journal of Sports Medicine. 43, 7, p. 1704-11 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Proteome-wide analysis of SUMO2 targets in response to pathological DNA replication stress in human cells
Bursomanno, S., Beli, P., Khan, A. M., Minocherhomji, S., Wagner, S. A., Bekker-Jensen, Simon Holst, Mailand, Niels, Choudhary, Chunaram, Hickson, Ian David & Liu, Ying, Jan 2015, In: DNA Repair. 25, p. 84-96 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Regulation of SUMO2 Target Proteins by the Proteasome in Human Cells Exposed to Replication Stress
Bursomanno, S., McGouran, J. F., Kessler, B. M., Hickson, Ian David & Liu, Ying, 2015, In: Journal of Proteome Research. 14, 4, p. 1687-99 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
FBH1 influences DNA replication fork stability and homologous recombination through ubiquitylation of RAD51
Chu, W. K., Payne, M. J., Beli, P., Hanada, K., Choudhary, C. & Hickson, Ian David, 2015, In: Nature Communications. 6, 7 p., 5931.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mitochondria in health and disease: 3rd annual conference of society for mitochondrial research and medicine - 19-20 december 2013 - bengaluru, India
Durhuus, J. A., Desler, Claus & Rasmussen, Lene Juel, Jan 2015, In: Mitochondrion. 20, p. 7-12 6 p.Research output: Contribution to journal › Conference article › Research › peer-review
- Published
FBH1 Catalyzes Regression of Stalled Replication Forks
Fugger, K., Mistrik, M., Neelsen, K. J., Yao, Q., Zellweger, R., Kousholt, A. N., Haahr, Peter Thorlund, Chu, W. K., Bartek, J., Lopes, M., Hickson, Ian David & Sørensen, Claus Storgaard, 10 Mar 2015, In: Cell Reports.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Lamin A/C-dependent interaction with 53BP1 promotes cellular responses to DNA damage
Gibbs-Seymour, I., Markiewicz, E., Bekker-Jensen, Simon Holst, Mailand, Niels & Hutchison, C. J., Apr 2015, In: Aging Cell. 14, 2, p. 162-9 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Ubiquitin-SUMO Circuitry Controls Activated Fanconi Anemia ID Complex Dosage in Response to DNA Damage
Gibbs-Seymour, I., Oka, Y., Rajendra, E., Weinert, B. T., Passmore, L. A., Patel, K. J., Olsen, Jesper Velgaard, Choudhary, Chunaram, Bekker-Jensen, Simon Holst & Mailand, Niels, Jan 2015, In: Molecular Cell. 57, 1, p. 150-64 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Neuroglial Transmission
Gundersen, V., Storm-Mathisen, J. & Bergersen, L. H., Jul 2015, In: Physiological Reviews. 95, 3, p. 695-726 32 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Insulin-like growth factor I enhances collagen synthesis in engineered human tendon tissue
Herchenhan, A., Bayer, M. L., Eliasson, P., Magnusson, Stig Peter & Kjær, Michael, Feb 2015, In: Growth Hormone & I G F Research. 25, 1, p. 13-19 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Lysyl oxidase activity is required for ordered collagen fibrillogenesis by tendon cells
Herchenhan, A., Uhlenbrock, F. K., Eliasson, P., Weis, M., Eyre, D., Kadler, K. E., Magnusson, Stig Peter & Kjær, Michael, 26 Jun 2015, In: The Journal of Biological Chemistry. 290, 26, p. 16440-50 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A novel method for determining human ex vivo submaximal skeletal muscle mitochondrial function
Hey-Mogensen, M., Gram, M., Jensen, M. B., Lund, M. T., Hansen, C. N., Scheibye-Knudsen, Morten, Bohr, Vilhelm & Dela, Flemming, 1 Sep 2015, In: The Journal of Physiology. 593, 17, p. 3991-4010 20 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
ATP induce an increase in intracellular Ca2+ in pericytes of the blood-brain barrier
Jensen, S. H., Helms, H. C. C., Jessen, S. B., Lauritzen, Martin, Waagepetersen, Helle S. & Larsen, Birger Brodin, 2 Nov 2015.Research output: Contribution to conference › Poster › Research › peer-review
- Published
Purinergic Signaling in Pericytes of the Blood-Brain Barrier
Jensen, S. H., Helms, H. C. C., Jessen, S. B., Lauritzen, Martin, Waagepetersen, Helle S. & Larsen, Birger Brodin, Jul 2015.Research output: Contribution to conference › Poster › Research › peer-review
- Published
GABAA Receptor-Mediated Bidirectional Control of Synaptic Activity, Intracellular Ca2+, Cerebral Blood Flow, and Oxygen Consumption in Mouse Somatosensory Cortex In Vivo
Jessen, S. B., Brazhe, A., Lind, Barbara Lykke, Mathiesen, C., Thomsen, K., Jensen, K. & Lauritzen, Martin, 2015, In: Cerebral Cortex. 25, 9, p. 2594-2609 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Matters of fiber size and myonuclear domain: does size matter more than age?
Karlsen, Anders, Couppé, Christian, Andersen, J. L., Mikkelsen, U. R., Nielsen, R. H., Magnusson, Stig Peter, Kjær, Michael & Mackey, Abigail, Dec 2015, In: Muscle & Nerve. 52, 6, p. 1040-1046 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Human exonuclease 1 (EXO1) activity characterization and its function on FLAP structures
Keijzers, G., Bohr, Vilhelm & Rasmussen, Lene Juel, 2015, In: Bioscience Reports. 35, 3, 13 p., e00206.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Exercise and Regulation of Bone and Collagen Tissue Biology
Kjær, Michael, Jørgensen, N. R., Heinemeier, K. M. & Magnusson, Stig Peter, Aug 2015, Molecular and Cellular Regulation of Adaptation to Exercise. Vol. 135. p. 259-91 33 p. (Progress in Molecular Biology and Translational Science, Vol. 135).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
Interaction of RECQ4 and MCM10 is important for efficient DNA replication origin firing in human cells
Kliszczak, M., Sedlackova, H., Pitchai, G. P., Streicher, W. W., Krejci, L. & Hickson, Ian David, 1 Dec 2015, In: OncoTarget. 6, 38, p. 40464-79 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The human myotendinous junction: An ultrastructural and 3D analysis study
Knudsen, A. B., Larsen, M., Mackey, Abigail, Hjort, M., Hansen, K. K., Qvortrup, Klaus, Kjær, Michael & Krogsgaard, Michael R., Feb 2015, In: Scandinavian Journal of Medicine & Science in Sports. 25, 1, p. E116-23Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Impaired dynamics and function of mitochondria caused by mtDNA toxicity leads to heart failure
Lauritzen, K. H., Kleppa, L., Aronsen, J. M., Eide, L., Carlsen, H., Haugen, O. P., Sjaastad, I., Klungland, A., Rasmussen, Lene Juel, Attramadal, H., Storm-Mathisen, J. & Bergersen, L. H., 1 Aug 2015, In: American Journal of Physiology: Heart and Circulatory Physiology. 309, 3, p. H434-H449 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Brain energy supply and metabolism in aging
Lauritzen, Martin, Nov 2015, In: Acta Physiologica. 215, S705, p. 59-59 1 p., S18-1.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
Increased Rrm2 gene dosage reduces fragile site breakage and prolongs survival of ATR mutant mice
Lopez-Contreras, Andres, Specks, J., Barlow, J. H., Ambrogio, C., Desler, Claus, Vikingsson, S., Rodrigo-Perez, S., Green, H., Rasmussen, Lene Juel, Murga, M., Nussenzweig, A. & Fernandez-Capetillo, O., 1 Apr 2015, In: Genes & Development. 29, 7, p. 690-5 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Prospective multi-centre randomised trial comparing induction of labour with a double-balloon catheter versus dinoprostone
Løkkegaard, Ellen Christine Leth, Lundstrøm, M., Kjær, Michael, Christensen, I. J., Pedersen, H. B. & Nyholm, H., 2015, In: Journal of Obstetrics and Gynaecology. 35, 8, p. 797-802 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Increased deoxythymidine triphosphate levels is a feature of relative cognitive decline
Desler, Claus, Frederiksen, J. H., Olsen, M. N. A., Maynard, S., Keijzers, G., Fagerlund, Birgitte, Mortensen, Erik Lykke, Osler, Merete, Lauritzen, Martin, Bohr, Vilhelm & Rasmussen, Lene Juel, Nov 2015, In: Mitochondrion. 25, p. 34-7 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Associations of subjective vitality with DNA damage, cardiovascular risk factors and physical performance
Maynard, S., Keijzers, G., Hansen, Åse Marie, Osler, Merete, Molbo, Drude, Bendix, L., Møller, Peter, Loft, Steffen, Moreno-Villanueva, M., Bürkle, A., Hvitby, C. P., Schurman, S. H., Stevnsner, T. V., Rasmussen, Lene Juel, Avlund, K. & Bohr, Vilhelm, Jan 2015, In: Acta Physiologica (Print). 213, 1, p. 156-170 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
DNA Damage, DNA Repair, Aging, and Neurodegeneration
Maynard, S., Fang, E. F., Scheibye-Knudsen, Morten, Croteau, D. L. & Bohr, Vilhelm, Oct 2015, In: Cold Spring Harbor Perspectives in Medicine. 5, 10, a025130.Research output: Contribution to journal › Journal article › Research › peer-review
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Life-long endurance exercise in humans: circulating levels of inflammatory markers and leg muscle size
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Activation of the ATR kinase by the RPA-binding protein ETAA1
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Is There a Link between Mitochondrial Reserve Respiratory Capacity and Aging?
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Protocol for the combined cardiometabolic deep phenotyping and registry-based 20-year follow-up study of the Inter99 cohort
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Muscle fascicle and sarcomere adaptation in response to Achilles tendon elongation in an animal model
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