Damage and Repair

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  1. 2017
  2. Published

    EXO1 (Exonuclease 1)

    Rasmussen, Lene Juel & Keijzers, G., 5 Jan 2017, Encyclopedia of Signaling Molecules . Choi, S. (ed.). New York: Springer, 7 p.

    Research output: Chapter in Book/Report/Conference proceeding › Encyclopedia chapter › Research

  3. Published

    Potential biomarkers of DNA replication stress in cancer

    Ren, L., Chen, L., Wu, Wei, Garribba, L., Tian, H., Liu, Z., Vogel, Ivan, Li, C., Hickson, Ian David & Liu, Ying, 2017, In: OncoTarget. 8, 23, p. 36996-37008 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Characterising the proximal patellar tendon attachment and its relationship to skeletal maturity in adolescent ballet dancers

    Rudavsky, A., Cook, J., Magnusson, Stig Peter, Kjær, Michael & Docking, S., Apr 2017, In: Muscles, Ligaments and Tendons Journal. 7, 2, p. 306-314 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Involvement of the DNA mismatch repair system in cisplatin sensitivity of testicular germ cell tumours

    Rudolph, C., Melau, C., Nielsen, J. E., Jensen, K. V., Liu, D., Pena-Diaz, J., Meyts, E. R., Rasmussen, Lene Juel & Jorgensen, A., 2017, In: Cellular Oncology. 40, 4, p. 341-355

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Knotty Problems during Mitosis: Mechanistic Insight into the Processing of Ultrafine DNA Bridges in Anaphase

    Sarlós, K., Biebricher, A., Petermann, E. J. G., Wuite, G. J. L. & Hickson, Ian David, 2017, In: Cold Spring Harbor Laboratory. Symposia on Quantitative Biology. 82, p. 187-195

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    An advanced glycation endproduct (AGE)-rich diet promotes accumulation of AGEs in Achilles tendon

    Skovgaard, D., Svensson, R. B., Scheijen, J., Eliasson, P., Mogensen, P., Hag, Anne Mette Fisker, Kjær, Michael, Schalkwijk, C. G., Schjerling, P., Magnusson, Stig Peter & Couppé, C., Mar 2017, In: Physiological Reports. 5, 6, 7 p., e13215.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Bacterial infection increases risk of carcinogenesis by targeting mitochondria

    Strickertsson, J. A. B., Desler, Claus & Rasmussen, Lene Juel, Dec 2017, In: Seminars in Cancer Biology. 47, p. 95-100 6 p.

    Research output: Contribution to journal › Review › Research › peer-review

  9. Published

    Multi-modal assessment of neurovascular coupling during cerebral ischaemia and reperfusion using remote middle cerebral artery occlusion

    Sutherland, B. A., Fordsmann, J. C., Martin, C., Neuhaus, A. A., Witgen, B. M., Hansen, H. P., Lønstrup, M., Couch, Y., Sibson, N. R., Lauritzen, Martin & Buchan, A. M., 2017, In: Journal of Cerebral Blood Flow and Metabolism. 37, 7, p. 2494-2508 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Disturbed mitochondrial function restricts glutamate uptake in the human Müller glia cell line, MIO-M1

    Vohra, Rupali, Gurubaran, I. S., Henriksen, U., Bergersen, L. H., Rasmussen, Lene Juel, Desler, C., Jensen, Dorte Skytt & Kolko, Miriam, 2017, In: Mitochondrion. 36, p. 52-59

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. 2016
  12. Published

    A short G1 phase imposes constitutive replication stress and fork remodelling in mouse embryonic stem cells

    Ahuja, A. K., Jodkowska, K., Teloni, F., Bizard, A. H., Zellweger, R., Herrador, R., Ortega, S., Hickson, Ian David, Altmeyer, M., Mendez, J. & Lopes, M., Feb 2016, In: Nature Communications. 7, 11 p., 10660.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    SDCCAG8 Interacts with RAB Effector Proteins RABEP2 and ERC1 and Is Required for Hedgehog Signaling

    Airik, R., Schueler, M., Airik, M., Cho, J., Ulanowicz, K. A., Porath, J. D., Hurd, T. W., Bekker-Jensen, Simon Holst, Schrøder, J. M., Andersen, J. S. & Hildebrandt, F., 2016, In: P L o S One. 11, 5, 19 p., e0156081.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Counteracting age-related loss of skeletal muscle mass: a clinical and ethnological trial on the role of protein supplementation and training load (CALM Intervention Study): study protocol for a randomized controlled trial

    Bechshøft, R., Reitelseder, S., Højfeldt, Grith Stougaard, Castro Mejia, J. L., Khakimov, Bekzod, Bin Ahmad, H. F., Kjær, Michael, Engelsen, Søren Balling, Laugesen, S. M. B., Rasmussen, Morten Arendt, Lassen, Aske Juul, Jensen, T., Beyer, N., Serena, A., Perez-Cueto, Federico J.A., Nielsen, Dennis Sandris, Jespersen, Astrid Pernille & Holm, L., 2016, In: Trials. 17, 17 p., 397.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    In response: Gamma oscillations or spikes?

    Benedek, Krisztina & Lauritzen, Martin, Sep 2016, In: Epilepsia. 57, 9, p. 1524–1525 2 p.

    Research output: Contribution to journal › Comment/debate › Research › peer-review

  16. Published

    Neocortical gamma oscillations in idiopathic generalized epilepsy

    Benedek, K., Berenyi, A., Gombkoto, P., Piilgaard, H. & Lauritzen, Martin, May 2016, In: Epilepsia. 57, 5, p. 796-804 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    RAD52 Facilitates Mitotic DNA Synthesis Following Replication Stress

    Bhowmick, Rahul, Minocherhomji, S. & Hickson, Ian David, 15 Dec 2016, In: Molecular Cell. 64, 6, p. 1117-1126 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    No additional effect of different types of physical activity on 10-hour muscle protein synthesis in elderly men on a controlled energy- and protein-sufficient diet

    Bulow, J., Agergaard, J., Kjær, Michael, Holm, L. & Reitelseder, S., 15 Jun 2016, In: Experimental Gerontology. 79, p. 16-25

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Glutamate-system defects behind psychiatric manifestations in a familial hemiplegic migraine type 2 disease-mutation mouse model

    Bøttger, P., Glerup, S., Gesslein, B., Illarionova, N. B., Isaksen, T. J., Heuck, A., Clausen, B. H., Füchtbauer, E., Gramsbergen, J. B., Gunnarson, E., Aperia, A., Lauritzen, Martin, Lambertsen, K. L., Nissen, P. & Lykke-Hartmann, K., 25 Feb 2016, In: Scientific Reports. 6, 21 p., 22047.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    LIFESTAT – Living with statins: An interdisciplinary project on the use of statins as a cholesterol-lowering treatment and for cardiovascular risk reduction

    Christensen, Christa Lykke, Helge, Jørn Wulff, Krasnik, Allan, Kriegbaum, Margit, Rasmussen, Lene Juel, Hickson, Ian David, Liisberg, Kasper Bering, Oxlund, Bjarke, Bruun, B., Lau, Sofie Rosenlund, Olsen, M. N. A., Andersen, John Sahl, Heltberg, Andreas Søndergaard, Kuhlman, A. C. B., Morville, T. H., Dohlmann, T. L., Larsen, Steen & Dela, Flemming, 2016, In: Scandinavian Journal of Public Health. 44, 5, p. 534-539 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Human Achilles tendon glycation and function in diabetes

    Couppé, Christian, Svensson, R. B., Madsen, M. K., Kovanen, V., Grosset, J., Snorgaard, O., Bencke, J., Larsen, J. O., Bandholm, Thomas Quaade, Christensen, T. M., Boesen, A., Helmark, I. C., Aagaard, P., Kjær, Michael & Magnusson, Stig Peter, Jan 2016, In: Journal of Applied Physiology. 120, 2, p. 130-137 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. Published

    Skeletal muscle adaptation to immobilization and subsequent retraining in elderly men: No effect of anti-inflammatory medication

    Dideriksen, K., Boesen, A. P., Kristiansen, J. F., Magnusson, Stig Peter, Schjerling, Peter, Holm, L. & Kjær, Michael, Sep 2016, In: Experimental Gerontology. 82, p. 8-18 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  23. Published

    Structural Analysis of a Complex between Small Ubiquitin-like Modifier 1 (SUMO1) and the ZZ Domain of CREB-binding Protein (CBP/p300) Reveals a New Interaction Surface on SUMO

    Diehl, C., Akke, M., Bekker-Jensen, Simon Holst, Mailand, Niels, Streicher, W. & Wikström, M., 10 Jun 2016, In: Journal of Biological Chemistry. 291, 24, p. 12658-12672 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    A new home for the Journal of Cerebral Blood Flow and Metabolism

    Dirnagl, U. & Lauritzen, Martin, Feb 2016, In: Journal of Cerebral Blood Flow and Metabolism. 36, 2, p. 277

    Research output: Contribution to journal › Editorial › Research › peer-review

  25. Published

    Ruptured human Achilles tendon has elevated metabolic activity up to 1 year after repair

    Eliasson, P., Couppé, C., Lonsdale, M., Svensson, R. B., Neergaard, C., Kjær, Michael, Friberg, L. & Magnusson, Stig Peter, Sep 2016, In: European Journal of Nuclear Medicine and Molecular Imaging. 43, 10, p. 1868-77 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    Physical activity as intervention for age-related loss of muscle mass and function: protocol for a randomised controlled trial (the LISA study)

    Eriksen, C. S., Garde, Ellen, Reislev, N. L., Wimmelmann, Cathrine Lawaetz, Bieler, T., Ziegler, A. K., Gylling, A. T., Dideriksen, K. J., Siebner, Hartwig Roman, Mortensen, Erik Lykke & Kjær, Michael, Dec 2016, In: B M J Open. 6, 12, p. 1-13 13 p., e012951.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    NAD(+) Replenishment Improves Lifespan and Healthspan in Ataxia Telangiectasia Models via Mitophagy and DNA Repair

    Fang, E. F., Kassahun, H., Croteau, D. L., Scheibye-Knudsen, M., Marosi, K., Lu, H., Shamanna, R. A., Kalyanasundaram, S., Bollineni, R. C., Wilson, M. A., Iser, W. B., Wollman, B. N., Morevati, M., Li, J., Kerr, J. S., Lu, Q., Waltz, T. B., Tian, J., Sinclair, D. A., Mattson, M. P. & 2 others, Nilsen, H. & Bohr, Vilhelm, 11 Oct 2016, In: Cell Metabolism. 24, 4, p. 566-581 16 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    Interventions for age-related diseases: Shifting the paradigm

    Figueira, I., Fernandes, A., Mladenovic Djordjevic, A., Lopez-Contreras, Andres, Henriques, C. M., Selman, C., Ferreiro, E., Gonos, E. S., Trejo, J. L., Misra, J., Rasmussen, Lene Juel, Xapelli, S., Ellam, T. & Bellantuono, I., Dec 2016, In: Mechanisms of Ageing and Development. 160, p. 69-92 24 p.

    Research output: Contribution to journal › Review › Research › peer-review

  29. Published

    Rad54 and Mus81 cooperation promotes DNA damage repair and restrains chromosome missegregation

    Ghamrasni, S. E., Cardoso, R., Li, L., Guturi, K. K. N., Bjerregaard, Victoria Alexandra, Liu, Ying, Venkatesan, S., Hande, M. P., Henderson, J. T., Sanchez, O., Hickson, Ian David, Hakem, A. & Hakem, R., 15 Sep 2016, In: Oncogene. 35, 37, p. 4836-4845 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    Activation of the ATR kinase by the RPA-binding protein ETAA1

    Haahr, Peter Thorlund, Hoffmann, Saskia, Tollenaere, M. A. X., Ho, T., Toledo Lazaro, L. I., Mann, Matthias, Bekker-Jensen, Simon Holst, Räschle, M. & Mailand, Niels, Nov 2016, In: Nature Cell Biology. 18, 11, p. 1196–1207

    Research output: Contribution to journal › Journal article › Research › peer-review

  31. Published

    Sex Hormones and Tendon

    Hansen, M. & Kjær, Michael, Aug 2016, Metabolic influences on risk for tendon disorders. Springer, Vol. 920. p. 139-149 11 p. (Advances in Experimental Medicine and Biology).

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  32. Published

    SCAI promotes DNA double-strand break repair in distinct chromosomal contexts

    Hansen, R. K., Mund, A., Poulsen, S. L., Sandoval, M., Klement, K., Tsouroula, K., Tollenaere, M. A. X., Räschle, M., Soria, R., Offermanns, S., Worzfeld, T., Grosse, R., Brandt, D. T., Rozell, B., Mann, M., Cole, F., Soutoglou, E., Goodarzi, A. A., Daniel, J. A., Mailand, N. & 1 others, Bekker-Jensen, Simon Holst, 7 Nov 2016, In: Nature Cell Biology. 18, 12, p. 1357–1366

    Research output: Contribution to journal › Letter › Research › peer-review

  33. Published

    Methods of Assessing Human Tendon Metabolism and Tissue Properties in Response to Changes in Mechanical Loading

    Heinemeier, K. M., Kjær, Michael & Magnusson, Stig Peter, 2016, Metabolic Influences on Risk for Tendon Disorders: Pary 1. Springer, Vol. 920. p. 97-106 10 p. (Advances in Experimental Medicine and Biology).

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  34. Published

    Radiocarbon dating reveals minimal collagen turnover in both healthy and osteoarthritic human cartilage

    Heinemeier, K. M., Schjerling, P., Heinemeier, J., Møller, M. B., Krogsgaard, Michael R., Grum-Schwensen, T., Petersen, Michael Mørk & Kjær, Michael, 6 Jul 2016, In: Science Translational Medicine. 8, 346, 346ra90.

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. Published

    Local trauma in human patellar tendon leads to widespread changes in the tendon gene expression

    Heinemeier, K. M., Lorentzen, M. P., Kildevang Jensen, J., Schjerling, P., Sennes, O., Narici, M. & Kjær, Michael, 1 May 2016, In: Journal of Applied Physiology. 120, 9, p. 1000-1010 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    DNA Damage Signaling Instructs Polyploid Macrophage Fate in Granulomas

    Herrtwich, L., Nanda, I., Evangelou, K., Nikolova, T., Horn, V., Sagar, Erny, D., Stefanowski, J., Rogell, L., Klein, C., Gharun, K., Follo, M., Seidl, M., Kremer, B., Muenke, N., Senges, J., Fliegauf, M., Aschman, T., Pfeifer, D., Sarrazin, S. & 18 others, Sieweke, M. H., Wagner, D., Dierks, C., Haaf, T., Ness, T., Zaiss, M. M., Voll, R. E., Deshmukh, S. D., Prinz, M., Goldmann, T., Hoelscher, C., Hauser, A. E., Lopez-Contreras, Andres, Gruen, D., Gorgoulis, V., Diefenbach, A., Henneke, P. & Triantafyllopoulou, A., 17 Nov 2016, In: Cell. 167, 5, p. 1264–1280.e18

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Published

    TRAIP is a PCNA-binding ubiquitin ligase that protects genome stability after replication stress

    Hoffmann, Saskia, Smedegaard, S., Nakamura, K., Mortuza, G. B., Räschle, M., Ibañez de Opakua, A., Oka, Y., Feng, Y., Blanco, F. J., Mann, Matthias, Montoya, Guillermo, Groth, Anja, Bekker-Jensen, Simon Holst & Mailand, Niels, 4 Jan 2016, In: The Journal of Cell Biology. 212, 1, p. 63-75

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. Published

    Behavioural effects of high fat diet in a mutant mouse model for the schizophrenia risk gene neuregulin 1: High fat diet in schizophrenia mouse model

    Holm-hansen, S., Low, J. K., Zieba, J., Gjedde, Albert, Bergersen, L. H. & Karl, T., 1 Mar 2016, In: Genes, Brain and Behavior. 15, 3, p. 295-304

    Research output: Contribution to journal › Journal article › Research › peer-review

  39. Published

    Isometric abdominal wall muscle strength assessment in individuals with incisional hernia: a prospective reliability study

    Jensen, K. K., Kjær, Michael & Jørgensen, Lars Nannestad, Dec 2016, In: Hernia. 20, 6, p. 831-837

    Research output: Contribution to journal › Journal article › Research › peer-review

  40. Published

    ATP induce intracellular calcium rises in cultures of primary brain pericytes

    Jensen, S. H., Helms, H. C. C., Jessen, S. B., Lauritzen, Martin, Waagepetersen, Helle S. & Larsen, Birger Brodin, Jun 2016.

    Research output: Contribution to conference › Conference abstract for conference › Research › peer-review

  41. Published

    Rises in intracellular calcium in primary brain pericytes are caused by ATP

    Jensen, S. H., Helms, H. C. C., Cai, Changsi, Lauritzen, Martin, Waagepetersen, Helle S. & Larsen, Birger Brodin, 2016. 1 p.

    Research output: Contribution to conference › Conference abstract for conference › Research › peer-review

  42. Published

    Exonuclease 1 and its versatile roles in DNA repair

    Keijzers, G., Liu, D. & Rasmussen, Lene Juel, 5 Aug 2016, In: Critical Reviews in Biochemistry and Molecular Biology. 51, 6, p. 440–451 12 p.

    Research output: Contribution to journal › Review › Research › peer-review

  43. Published

    Activity-Dependent Calcium, Oxygen, and Vascular Responses in a Mouse Model of Familial Hemiplegic Migraine Type 1

    Khennouf, Lila, Gesslein, B., Lind, Barbara Lykke, van den Maagdenberg, A. M. J. M. & Lauritzen, Martin, Aug 2016, In: Annals of Neurology. 80, 2, p. 219-232

    Research output: Contribution to journal › Journal article › Research › peer-review

  44. Published

    Lactate Transport and Receptor Actions in Retina: Potential Roles in Retinal Function and Disease

    Kolko, Miriam, Vosborg, F., Henriksen, J. U. L., Hasan-Olive, M. M., Diget, E. H., Vohra, Rupali, Gurubaran, I. S., Gjedde, Albert, Mariga, S. T., Jensen, Dorte Skytt, Utheim, T. P., Storm-Mathisen, J. & Bergersen, L. H., 1 Jun 2016, In: Neurochemical Research. 41, 6, p. 1229-1236

    Research output: Contribution to journal › Journal article › Research › peer-review

  45. Published

    A ketogenic diet accelerates neurodegeneration in mice with induced mitochondrial DNA toxicity in the forebrain

    Lauritzen, K. H., Hasan-Olive, M. M., Regnell, C. E., Kleppa, L., Scheibye-Knudsen, Morten, Gjedde, Albert, Klungland, A., Bohr, Vilhelm, Storm-Mathisen, J. & Bergersen, L. H., Dec 2016, In: Neurobiology of Aging. 48, p. 34-47

    Research output: Contribution to journal › Journal article › Research › peer-review

  46. Published

    'Spreading depression of Leão' and its emerging relevance to acute brain injury in humans

    Lauritzen, Martin & Strong, A. J., 2016, In: Journal of Cerebral Blood Flow and Metabolism. 37, 5, p. 1553-1570

    Research output: Contribution to journal › Review › Research › peer-review

  47. Published

    The Journal of Cerebral Blood Flow and Metabolism clinical, inaugural issue

    Lauritzen, Martin & Dirnagl, U., Jan 2016, In: Journal of Cerebral Blood Flow and Metabolism. 36, 1, p. 3-3

    Research output: Contribution to journal › Editorial › Research

  48. Published

    USP7 is a SUMO deubiquitinase essential for DNA replication

    Lecona, E., Rodriguez-Acebes, S., Specks, J., Lopez-Contreras, Andres, Ruppen, I., Murga, M., Muñoz, J., Mendez, J. & Fernandez-Capetillo, O., 23 Apr 2016, In: Nature Structural and Molecular Biology. 23, 4, p. 270-277 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  49. Published

    RECQL4 Promotes DNA End Resection in Repair of DNA Double-Strand Breaks

    Lu, H., Shamanna, R. A., Keijzers, G., Anand, R., Rasmussen, Lene Juel, Cejka, P., Croteau, D. L. & Bohr, Vilhelm, 28 Jun 2016, In: Cell Reports. 16, 1, p. 161-173 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  50. Published

    Activation of satellite cells and the regeneration of human skeletal muscle are expedited by ingestion of nonsteroidal anti-inflammatory medication

    Mackey, Abigail, Rasmussen, L. K., Kadi, F., Schjerling, Peter, Helmark, I. C., Ponsot, E., Aagaard, P., Durigan, J. L. Q. & Kjær, Michael, 2 Mar 2016, In: FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 30, 6, p. 2266-2281

    Research output: Contribution to journal › Journal article › Research › peer-review

  51. Published

    Collagen Homeostasis and Metabolism

    Magnusson, Stig Peter, Heinemeier, K. M. & Kjær, Michael, 2016, Metabolic Influences on Risk for Tendon Disorders. Springer, Vol. 920 . p. 11-25 15 p. (Advances in Experimental Medicine and Biology, Vol. 920).

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  52. Published

    3-Hydroxybutyrate regulates energy metabolism and induces BDNF expression in cerebral cortical neurons

    Marosi, K., Kim, S. W., Moehl, K., Scheibye-Knudsen, Morten, Cheng, A., Cutler, R., Camandola, S. & Mattson, M. P., Dec 2016, In: Journal of Neurochemistry. 139, 5, p. 769-781 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

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