Damage and Repair

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  1. 2016
  2. Published

    Effects of Sex, Strain, and Energy Intake on Hallmarks of Aging in Mice

    Mitchell, S. J., Madrigal-Matute, J., Scheibye-Knudsen, M., Fang, E., Aon, M., Gonzalez-Reyes, J. A., Cortassa, S., Kaushik, S., Gonzalez-Freire, M., Patel, B., Wahl, D., Ali, A., Calvo-Rubio, M., Buron, M. I., Guiterrez, V., Ward, T. M., Palacios, H. H., Cai, H., Frederick, D. W., Hine, C. & 27 others, Broeskamp, F., Habering, L., Dawson, J., Beasley, T. M., Wan, J., Ikeno, Y., Hubbard, G., Becker, K. G., Zhang, Y., Bohr, V. A., Longo, D. L., Navas, P., Ferrucci, L., Sinclair, D. A., Cohen, P., Egan, J. M., Mitchell, J. R., Baur, J. A., Allison, D. B., Anson, R. M., Villalba, J. M., Madeo, F., Cuervo, A. M., Pearson, K. J., Ingram, D. K., Bernier, M. & de Cabo, R., 14 Jun 2016, In: Cell Metabolism. 23, 6, p. 1093-1112

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    PICH promotes mitotic chromosome segregation: Identification of a novel role in rDNA disjunction

    Nielsen, Christian Friberg & Hickson, Ian David, 17 Oct 2016, In: Cell Cycle. 15, 20, p. 2704-2711 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    Efficacy of ATR inhibitors as single agents in Ewing sarcoma

    Nieto-Soler, M., Morgado-Palacin, I., Lafarga, V., Lecona, E., Murga, M., Callen, E., Azorin, D., Alonso, J., Lopez-Contreras, Andres, Nussenzweig, A. & Fernandez-Capetillo, O., 26 Aug 2016, In: OncoTarget. 7, 37, p. 58759-58767

    Research output: Contribution to journal › Journal article › Research › peer-review

  5. Published

    Acquired Localized Cutis Laxa due to Increased Elastin Turnover

    Nygaard, R. H., Maynard, S., Schjerling, P., Kjær, M., Qvortrup, Klaus, Bohr, Vilhelm, Rasmussen, Lene Juel, Jemec, Gregor & Heidenheim, M., 14 Jun 2016, In: Case Reports in Dermatology. 8, 1, p. 42-51 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  6. Published

    Approaches to diagnose DNA mismatch repair gene defects in cancer

    Peña-Diaz, J. & Rasmussen, Lene Juel, Feb 2016, In: DNA Repair. 38, p. 147-154 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Published

    Characterization of the NTPR and BD1 interacting domains of the human PICH-BEND3 complex

    Pitchai, G. P., Hickson, Ian David, Streicher, W., Montoya, Guillermo & Mesa, Pablo, Aug 2016, In: Acta Crystallographica. Section F: Structural Biology and Crystallization Communications Online. 72, 8, p. 646-651 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Cognitive Change during the Life Course and Leukocyte Telomere Length in Late Middle-Aged Men

    Rask, L., Bendix, L., Harbo, M., Fagerlund, Birgitte, Mortensen, Erik Lykke, Lauritzen, Martin & Osler, Merete, 9 Dec 2016, In: Frontiers in Aging Neuroscience. 8, 7 p., 300.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    H4K20me0 marks post-replicative chromatin and recruits the TONSL–MMS22L DNA repair complex

    Saredi, G., Huang, H., Hammond, Colin, Alabert, C., Bekker-Jensen, Simon Holst, Forne, I., Reveron-Gomez, Nazaret, Foster, B. M., Mlejnkova, L., Bartke, T., Cejka, P., Mailand, Niels, Imhof, A., Patel, D. J. & Groth, Anja, 30 Jun 2016, In: Nature. 534, 7609, p. 714-8 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    Cockayne syndrome group A and B proteins converge on transcription-linked resolution of non-B DNA

    Scheibye-Knudsen, M., Tseng, A., Jensen, M. B., Scheibye-Alsing, K., Fang, E. F., Iyama, T., Bharti, S. K., Marosi, K., Froetscher, L., Kassahun, H., Eckley, D. M., Maul, R. W., Bastian, P., De, S., Ghosh, S., Nilsen, H., Goldberg, I. G., Mattson, M. P., Wilson, D. M. . III., Brosh, R. M. . J. & 2 others, Gorospe, M. & Bohr, Vilhelm, 1 Nov 2016, In: National Academy of Sciences. Proceedings. 113, 44, p. 12502-12507

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Published

    Neurodegeneration in Accelerated Aging

    Scheibye-Knudsen, Morten, Nov 2016, In: Danish Medical Journal. 63, 11, 21 p., B5308.

    Research output: Contribution to journal › Review › Research › peer-review

  12. Published

    Neurodegeneration in accelerated aging

    Scheibye-Knudsen, Morten, 2016, 190 p.

    Research output: Book/Report › Doctoral thesis › Research

  13. Published

    Regulation of DNA double-strand break repair by ubiquitin and ubiquitin-like modifiers

    Schwertman, P., Bekker-Jensen, Simon Holst & Mailand, Niels, Jun 2016, In: Nature Reviews. Molecular Cell Biology. 17, 6, p. 379-94 16 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. Published

    Glia-Neuron Interactions in the Retina Can Be Studied in Cocultures of Muller Cells and Retinal Ganglion Cells

    Jensen, Dorte Skytt, Toft-Kehler, A. K., Braendstrup, C. T., Cejvanovic, S., Gurubaran, I. S., Bergersen, L. H. & Kolko, Miriam, 2016, In: Journal of Biomedicine and Biotechnology. 2016, 11 p., 1087647.

    Research output: Contribution to journal › Journal article › Research › peer-review

  15. Published

    Effect of aging and exercise on the tendon

    Svensson, R. B., Heinemeier, K. M., Couppé, Christian, Kjær, Michael & Magnusson, Stig Peter, 1 Dec 2016, In: Journal of Applied Physiology. 121, 6, p. 1237-1246 10 p.

    Research output: Contribution to journal › Review › Research › peer-review

  16. Published

    A Novel Rrm3 Function in Restricting DNA Replication via an Orc5-Binding Domain Is Genetically Separable from Rrm3 Function as an ATPase/Helicase in Facilitating Fork Progression

    Syed, S., Desler, Claus, Rasmussen, Lene Juel & Schmidt, K. H., Dec 2016, In: P L o S Genetics. 12, 12, 28 p., e1006451.

    Research output: Contribution to journal › Journal article › Research › peer-review

  17. Published

    Elevated p16ink4a Expression in Human Labial Salivary Glands as a Potential Correlate of Cognitive Aging in Late Midlife

    Sørensen, Christiane Elisabeth, Tritsaris, Katerina, Reibel, Jesper, Lauritzen, Martin, Mortensen, Erik Lykke, Osler, Merete & Pedersen, Anne Marie Lynge, 2016, In: PloS one. 11, 3, p. e0152612

    Research output: Contribution to journal › Journal article › Research › peer-review

  18. Published

    Early detection of Alzheimer's disease using MRI hippocampal texture

    Sørensen, L., Igel, Christian, Hansen, N. L., Osler, Merete, Lauritzen, Martin, Rostrup, Egill & Nielsen, Mads, 2016, In: Human Brain Mapping. 37, 3, p. 1148-1161 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Oxidative Stress-Induced Dysfunction of Muller Cells During Starvation

    Toft-Kehler, A. K., Gurubaran, I. S., Desler, Claus, Rasmussen, Lene Juel, Jensen, Dorte Skytt & Kolko, Miriam, May 2016, In: Investigative Ophthalmology & Visual Science. 57, 6, p. 2721-2728

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    Melatonin and cortisol profiles in late midlife and their association with age-related changes in cognition

    Waller, K. L., Mortensen, Erik Lykke, Avlund, K., Fagerlund, Birgitte, Lauritzen, Martin, Gammeltoft, S. & Jennum, Poul, 2016, In: Nature and Science of Sleep. 8, p. 47-53 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Subjective sleep quality and daytime sleepiness in late midlife and their association with age-related changes in cognition

    Waller, K. L., Mortensen, Erik Lykke, Avlund, K., Osler, Merete, Fagerlund, Birgitte, Lauritzen, Martin & Jennum, Poul, Jan 2016, In: Sleep Medicine. 17, p. 165-73 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  22. 2015
  23. Published

    Spreading Depression, Spreading Depolarizations, and the Cerebral Vasculature

    Ayata, C. & Lauritzen, Martin, Jul 2015, In: Physiological Reviews. 95, 3, p. 953-993 41 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  24. Published

    RNF138 joins the HR team

    Bekker-Jensen, Simon Holst & Mailand, Niels, Oct 2015, In: Nature Cell Biology. 17, 11, p. 1375-7 3 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  25. Published

    Lactate transport and signaling in the brain: Potential therapeutic targets and roles in body-brain interaction

    Bergersen, L. H., Feb 2015, In: Journal of Cerebral Blood Flow and Metabolism. 35, 2, p. 176-185 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  26. Published

    Heavy Slow Resistance Versus Eccentric Training as Treatment for Achilles Tendinopathy: A Randomized Controlled Trial

    Beyer, R., Kongsgaard, M., Hougs Kjær, B., Øhlenschlæger, Tommy Frisgaard, Kjær, Michael & Magnusson, Stig Peter, Jul 2015, In: American Journal of Sports Medicine. 43, 7, p. 1704-11 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  27. Published

    Proteome-wide analysis of SUMO2 targets in response to pathological DNA replication stress in human cells

    Bursomanno, S., Beli, P., Khan, A. M., Minocherhomji, S., Wagner, S. A., Bekker-Jensen, Simon Holst, Mailand, Niels, Choudhary, Chunaram, Hickson, Ian David & Liu, Ying, Jan 2015, In: DNA Repair. 25, p. 84-96 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  28. Published

    Regulation of SUMO2 Target Proteins by the Proteasome in Human Cells Exposed to Replication Stress

    Bursomanno, S., McGouran, J. F., Kessler, B. M., Hickson, Ian David & Liu, Ying, 2015, In: Journal of Proteome Research. 14, 4, p. 1687-99 13 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  29. Published

    FBH1 influences DNA replication fork stability and homologous recombination through ubiquitylation of RAD51

    Chu, W. K., Payne, M. J., Beli, P., Hanada, K., Choudhary, C. & Hickson, Ian David, 2015, In: Nature Communications. 6, 7 p., 5931.

    Research output: Contribution to journal › Journal article › Research › peer-review

  30. Published

    Mitochondria in health and disease: 3rd annual conference of society for mitochondrial research and medicine - 19-20 december 2013 - bengaluru, India

    Durhuus, J. A., Desler, Claus & Rasmussen, Lene Juel, Jan 2015, In: Mitochondrion. 20, p. 7-12 6 p.

    Research output: Contribution to journal › Conference article › Research › peer-review

  31. Published

    FBH1 Catalyzes Regression of Stalled Replication Forks

    Fugger, K., Mistrik, M., Neelsen, K. J., Yao, Q., Zellweger, R., Kousholt, A. N., Haahr, Peter Thorlund, Chu, W. K., Bartek, J., Lopes, M., Hickson, Ian David & Sørensen, Claus Storgaard, 10 Mar 2015, In: Cell Reports.

    Research output: Contribution to journal › Journal article › Research › peer-review

  32. Published

    Lamin A/C-dependent interaction with 53BP1 promotes cellular responses to DNA damage

    Gibbs-Seymour, I., Markiewicz, E., Bekker-Jensen, Simon Holst, Mailand, Niels & Hutchison, C. J., Apr 2015, In: Aging Cell. 14, 2, p. 162-9 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  33. Published

    Ubiquitin-SUMO Circuitry Controls Activated Fanconi Anemia ID Complex Dosage in Response to DNA Damage

    Gibbs-Seymour, I., Oka, Y., Rajendra, E., Weinert, B. T., Passmore, L. A., Patel, K. J., Olsen, Jesper Velgaard, Choudhary, Chunaram, Bekker-Jensen, Simon Holst & Mailand, Niels, Jan 2015, In: Molecular Cell. 57, 1, p. 150-64 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  34. Published

    Neuroglial Transmission

    Gundersen, V., Storm-Mathisen, J. & Bergersen, L. H., Jul 2015, In: Physiological Reviews. 95, 3, p. 695-726 32 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  35. Published

    Insulin-like growth factor I enhances collagen synthesis in engineered human tendon tissue

    Herchenhan, A., Bayer, M. L., Eliasson, P., Magnusson, Stig Peter & Kjær, Michael, Feb 2015, In: Growth Hormone & I G F Research. 25, 1, p. 13-19 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  36. Published

    Lysyl oxidase activity is required for ordered collagen fibrillogenesis by tendon cells

    Herchenhan, A., Uhlenbrock, F. K., Eliasson, P., Weis, M., Eyre, D., Kadler, K. E., Magnusson, Stig Peter & Kjær, Michael, 26 Jun 2015, In: The Journal of Biological Chemistry. 290, 26, p. 16440-50 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  37. Published

    A novel method for determining human ex vivo submaximal skeletal muscle mitochondrial function

    Hey-Mogensen, M., Gram, M., Jensen, M. B., Lund, M. T., Hansen, C. N., Scheibye-Knudsen, Morten, Bohr, Vilhelm & Dela, Flemming, 1 Sep 2015, In: The Journal of Physiology. 593, 17, p. 3991-4010 20 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  38. Published

    ATP induce an increase in intracellular Ca2+ in pericytes of the blood-brain barrier

    Jensen, S. H., Helms, H. C. C., Jessen, S. B., Lauritzen, Martin, Waagepetersen, Helle S. & Larsen, Birger Brodin, 2 Nov 2015.

    Research output: Contribution to conference › Poster › Research › peer-review

  39. Published

    Purinergic Signaling in Pericytes of the Blood-Brain Barrier

    Jensen, S. H., Helms, H. C. C., Jessen, S. B., Lauritzen, Martin, Waagepetersen, Helle S. & Larsen, Birger Brodin, Jul 2015.

    Research output: Contribution to conference › Poster › Research › peer-review

  40. Published

    GABAA Receptor-Mediated Bidirectional Control of Synaptic Activity, Intracellular Ca2+, Cerebral Blood Flow, and Oxygen Consumption in Mouse Somatosensory Cortex In Vivo

    Jessen, S. B., Brazhe, A., Lind, Barbara Lykke, Mathiesen, C., Thomsen, K., Jensen, K. & Lauritzen, Martin, 2015, In: Cerebral Cortex. 25, 9, p. 2594-2609 16 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  41. Published

    Matters of fiber size and myonuclear domain: does size matter more than age?

    Karlsen, Anders, Couppé, Christian, Andersen, J. L., Mikkelsen, U. R., Nielsen, R. H., Magnusson, Stig Peter, Kjær, Michael & Mackey, Abigail, Dec 2015, In: Muscle & Nerve. 52, 6, p. 1040-1046 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  42. Published

    Human exonuclease 1 (EXO1) activity characterization and its function on FLAP structures

    Keijzers, G., Bohr, Vilhelm & Rasmussen, Lene Juel, 2015, In: Bioscience Reports. 35, 3, 13 p., e00206.

    Research output: Contribution to journal › Journal article › Research › peer-review

  43. Published

    Exercise and Regulation of Bone and Collagen Tissue Biology

    Kjær, Michael, Jørgensen, N. R., Heinemeier, K. M. & Magnusson, Stig Peter, Aug 2015, Molecular and Cellular Regulation of Adaptation to Exercise. Vol. 135. p. 259-91 33 p. (Progress in Molecular Biology and Translational Science, Vol. 135).

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  44. Published

    Interaction of RECQ4 and MCM10 is important for efficient DNA replication origin firing in human cells

    Kliszczak, M., Sedlackova, H., Pitchai, G. P., Streicher, W. W., Krejci, L. & Hickson, Ian David, 1 Dec 2015, In: OncoTarget. 6, 38, p. 40464-79 16 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  45. Published

    The human myotendinous junction: An ultrastructural and 3D analysis study

    Knudsen, A. B., Larsen, M., Mackey, Abigail, Hjort, M., Hansen, K. K., Qvortrup, Klaus, Kjær, Michael & Krogsgaard, Michael R., Feb 2015, In: Scandinavian Journal of Medicine & Science in Sports. 25, 1, p. E116-23

    Research output: Contribution to journal › Journal article › Research › peer-review

  46. Published

    Impaired dynamics and function of mitochondria caused by mtDNA toxicity leads to heart failure

    Lauritzen, K. H., Kleppa, L., Aronsen, J. M., Eide, L., Carlsen, H., Haugen, O. P., Sjaastad, I., Klungland, A., Rasmussen, Lene Juel, Attramadal, H., Storm-Mathisen, J. & Bergersen, L. H., 1 Aug 2015, In: American Journal of Physiology: Heart and Circulatory Physiology. 309, 3, p. H434-H449 16 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  47. Published

    Brain energy supply and metabolism in aging

    Lauritzen, Martin, Nov 2015, In: Acta Physiologica. 215, S705, p. 59-59 1 p., S18-1.

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  48. Published

    Increased Rrm2 gene dosage reduces fragile site breakage and prolongs survival of ATR mutant mice

    Lopez-Contreras, Andres, Specks, J., Barlow, J. H., Ambrogio, C., Desler, Claus, Vikingsson, S., Rodrigo-Perez, S., Green, H., Rasmussen, Lene Juel, Murga, M., Nussenzweig, A. & Fernandez-Capetillo, O., 1 Apr 2015, In: Genes & Development. 29, 7, p. 690-5 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  49. Published

    Prospective multi-centre randomised trial comparing induction of labour with a double-balloon catheter versus dinoprostone

    Løkkegaard, Ellen Christine Leth, Lundstrøm, M., Kjær, Michael, Christensen, I. J., Pedersen, H. B. & Nyholm, H., 2015, In: Journal of Obstetrics and Gynaecology. 35, 8, p. 797-802 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  50. Published

    Increased deoxythymidine triphosphate levels is a feature of relative cognitive decline

    Desler, Claus, Frederiksen, J. H., Olsen, M. N. A., Maynard, S., Keijzers, G., Fagerlund, Birgitte, Mortensen, Erik Lykke, Osler, Merete, Lauritzen, Martin, Bohr, Vilhelm & Rasmussen, Lene Juel, Nov 2015, In: Mitochondrion. 25, p. 34-7 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  51. Published

    Associations of subjective vitality with DNA damage, cardiovascular risk factors and physical performance

    Maynard, S., Keijzers, G., Hansen, Åse Marie, Osler, Merete, Molbo, Drude, Bendix, L., Møller, Peter, Loft, Steffen, Moreno-Villanueva, M., Bürkle, A., Hvitby, C. P., Schurman, S. H., Stevnsner, T. V., Rasmussen, Lene Juel, Avlund, K. & Bohr, Vilhelm, Jan 2015, In: Acta Physiologica (Print). 213, 1, p. 156-170 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  52. Published

    DNA Damage, DNA Repair, Aging, and Neurodegeneration

    Maynard, S., Fang, E. F., Scheibye-Knudsen, Morten, Croteau, D. L. & Bohr, Vilhelm, Oct 2015, In: Cold Spring Harbor Perspectives in Medicine. 5, 10, a025130.

    Research output: Contribution to journal › Journal article › Research › peer-review

  53. Published

    Defective mitochondrial respiration, altered dNTP pools and reduced AP endonuclease 1 activity in peripheral blood mononuclear cells of Alzheimer's disease patients

    Maynard, S., Hejl, Anne-Mette, Dinh, T. T. S., Keijzers, G., Hansen, Åse Marie, Desler, Claus, Moreno-Villanueva, M., Bürkle, A., Rasmussen, Lene Juel, Waldemar, Gunhild & Bohr, Vilhelm, Oct 2015, In: Aging. 7, 10, p. 793-815 23 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  54. Published

    Preserved skeletal muscle protein anabolic response to acute exercise and protein intake in well-treated rheumatoid arthritis patients

    Mikkelsen, U. R., Dideriksen, K., Andersen, M. B., Boesen, A., Malmgaard-Clausen, N. M., Sørensen, I. J., Schjerling, Peter, Kjær, Michael & Holm, L., 2015, In: Arthritis Research & Therapy (Print). 17, p. 271

    Research output: Contribution to journal › Journal article › Research › peer-review

  55. Published

    Replication stress activates DNA repair synthesis in mitosis

    Minocherhomji, S., Ying, S., Bjerregaard, Victoria Alexandra, Bursomanno, S., Aleliunaite, A., Wu, Wei, Mankouri, H. W., Shen, H., Liu, Ying & Hickson, Ian David, 10 Dec 2015, In: Nature. 528, 7581, p. 286-90 5 p.

    Research output: Contribution to journal › Letter › Research › peer-review

  56. Published

    The lactate receptor, G-protein-coupled receptor 81/hydroxycarboxylic acid receptor 1: Expression and action in brain

    Morland, C., Lauritzen, K. H., Puchades, M., Holm-Hansen, S., Andersson, K., Gjedde, Albert, Attramadal, H., Storm-Mathisen, J. & Bergersen, L. H., Jul 2015, In: Journal of Neuroscience Research. 93, 7, p. 1045-1055 11 p.

    Research output: Contribution to journal › Review › Research › peer-review

  57. Published

    Crystal structure of the Bloom's syndrome helicase indicates a role for the HRDC domain in conformational changes

    Newman, J. A., Savitsky, P., Allerston, C. K., Bizard, A. H., Özer, Ö., Sarlós, K., Liu, Ying, Pardon, E., Steyaert, J., Hickson, Ian David & Gileadi, O., 2015, In: Nucleic Acids Research. 43, 10, p. 5221-35 15 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  58. Published

    PICH promotes sister chromatid disjunction and co-operates with topoisomerase II in mitosis

    Nielsen, Christian Friberg, Huttner, D., Bizard, A. H., Hirano, S., Li, T., Palmai-Pallag, T., Bjerregaard, Victoria Alexandra, Liu, Ying, Nigg, E. A., Wang, L. H. & Hickson, Ian David, 2015, In: Nature Communications. 6, 15 p., 8962.

    Research output: Contribution to journal › Journal article › Research › peer-review

  59. Published

    Ubiquitin-like protein UBL5 promotes the functional integrity of the Fanconi anemia pathway

    Oka, Y., Bekker-Jensen, Simon Holst & Mailand, Niels, 9 Apr 2015, In: E M B O Journal. 34, p. 1385-1398

    Research output: Contribution to journal › Journal article › Research › peer-review

  60. Published

    Astrocytes gate synaptic transmission from unmyelinated sensory afferents

    Perrier, Jean-Francois Marie, Christensen, R. K., Delgado-Lezama, R., Russo, R., Lind, Barbara Lykke, Alcocer, E. L., Fabbiani, G., Schmitt, Nicole, Lauritzen, Martin, Petersen, A. V. & Carlsen, E. M., Aug 2015, In: Glia. 63, S1, p. E241-E241 T08-22B .

    Research output: Contribution to journal › Conference abstract in journal › Research › peer-review

  61. Published

    Influence of ornithine decarboxylase antizymes and antizyme inhibitors on agmatine uptake by mammalian cells

    Ramos-Molina, B., Lopez-Contreras, Andres, Lambertos, A., Dardonville, C., Cremades, A. & Peñafiel, R., 2015, In: Amino Acids. 47, 5, p. 1025-34 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  62. Published

    The challenges of human population ageing

    Sander, M., Oxlund, Bjarke, Jespersen, Astrid Pernille, Krasnik, Allan, Mortensen, Erik Lykke, Westendorp, Rudi GJ & Rasmussen, Lene Juel, Mar 2015, In: Age and Ageing. 44, 2, p. 185-7 3 p.

    Research output: Contribution to journal › Journal article › Communication

  63. Published

    A Single Conserved Residue Mediates Binding of the Ribonucleotide Reductase Catalytic Subunit RRM1 to RRM2 and Is Essential for Mouse Development

    Specks, J., Lecona, E., Lopez-Contreras, Andres & Fernandez-Capetillo, O., Sep 2015, In: Molecular and Cellular Biology. 35, 17, p. 2910-2917 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  64. Published

    Histone H1 couples initiation and amplification of ubiquitin signalling after DNA damage

    Thorslund, T., Ripplinger, A., Hoffmann, Saskia, Wild, T., Uckelmann, M., Villumsen, B., Narita, Takeo, Sixma, T. K., Choudhary, Chunaram, Bekker-Jensen, Simon Holst & Mailand, Niels, 19 Nov 2015, In: Nature. 527, 7578, p. 389-93 5 p.

    Research output: Contribution to journal › Letter › Research › peer-review

  65. Published

    Centriolar satellites: key mediators of centrosome functions

    Tollenaere, M. A. X., Mailand, Niels & Bekker-Jensen, Simon Holst, Jan 2015, In: Cellular and molecular life sciences : CMLS. 73, 1, p. 11-23 13 p.

    Research output: Contribution to journal › Review › Research › peer-review

  66. Published

    p38- and MK2-dependent signalling promotes stress-induced centriolar satellite remodelling via 14-3-3-dependent sequestration of CEP131/AZI1

    Tollenaere, M. A. X., Villumsen, B. H., Blasius, M., Nielsen, J. C., Wagner, S. A., Bartek, J., Beli, P., Mailand, Niels & Bekker-Jensen, Simon Holst, 30 Nov 2015, In: Nature Communications. 6, p. 1-12 12 p., 10075.

    Research output: Contribution to journal › Journal article › Research › peer-review

  67. Published

    Acute MUS81 depletion leads to replication fork slowing and a constitutive DNA damage response

    Xing, M., Wang, X., Palmai-Pallag, T., Shen, H., Helleday, T., Hickson, Ian David & Ying, S., 2015, In: OncoTarget. 6, 35, p. 37638-37646 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  68. 2014
  69. Published

    Renal-Retinal Ciliopathy Gene Sdccag8 Regulates DNA Damage Response Signaling

    Airik, R., Slaats, G. G., Guo, Z., Weiss, A., Khan, N., Ghosh, A., Hurd, T. W., Bekker-Jensen, Simon Holst, Schrøder, J. M., Elledge, S. J., Andersen, J. S., Kispert, A., Castelli, M., Boletta, A., Giles, R. H. & Hildebrandt, F., Nov 2014, In: Journal of the American Society of Nephrology:JASN. 25, 11, p. 2573-83 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  70. Published

    Overexpression of DNA ligase III in mitochondria protects cells against oxidative stress and improves mitochondrial DNA base excision repair

    Akbari, M., Keijzers, G., Maynard, S., Scheibye-Knudsen, M., Desler, Claus, Hickson, Ian David & Bohr, Vilhelm, Apr 2014, In: DNA Repair. 16, p. 44-53 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  71. Published

    Bengt Saltin (1935-2014)

    Bangsbo, Jens, Kjær, Michael & Hellsten, Ylva, 2014, In: Journal of Physiology. 592, 23, p. 5149-5151 3 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  72. Published

    Release of tensile strain on engineered human tendon tissue disturbs cell adhesions, changes matrix architecture, and induces an inflammatory phenotype

    Bayer, M. L., Schjerling, Peter, Herchenhan, A., Zeltz, C., Heinemeier, K. M., Christensen, L., Krogsgaard, Michael R., Gullberg, D. & Kjær, Michael, 2014, In: PLOS ONE. 9, 1, p. 1-16 16 p., e86078.

    Research output: Contribution to journal › Journal article › Research › peer-review

  73. Published

    Dynamics of the DNA repair proteins WRN and BLM in the nucleoplasm and nucleoli

    Bendtsen, K. M., Jensen, M. B., May, A., Rasmussen, Lene Juel, Trusina, Ala, Bohr, Vilhelm & Jensen, Mogens Høgh, 14 Nov 2014, In: European Biophysics Journal. 43, 10-11, p. 509-516

    Research output: Contribution to journal › Journal article › Research › peer-review

  74. Published

    The Dissolution of Double Holliday Junctions

    Bizard, A. H. & Hickson, Ian David, 1 Jul 2014, In: Cold Spring Harbor perspectives in biology. 6, p. 1-16 16 p., a016477.

    Research output: Contribution to journal › Review › Research › peer-review

  75. Published

    Structural and mechanistic insight into Holliday-junction dissolution by topoisomerase IIIα and RMI1

    Bocquet, N., Bizard, A. H., Abdulrahman, W., Larsen, N. B., Faty, M., Cavadini, S., Bunker, R. D., Kowalczykowski, S. C., Cejka, P., Hickson, Ian David & Thomä, N. H., Mar 2014, In: Nature Structural and Molecular Biology. 21, 3, p. 261-8 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  76. Published

    Effect of growth hormone on aging connective tissue in muscle and tendon - gene expression, morphology and function following immobilization and rehabilitation

    Boesen, A. P., Dideriksen, K. J., Couppé, Christian, Magnusson, Stig Peter, Schjerling, Peter, Boesen, M., Aagaard, P., Kjær, Michael & Langberg, Henning, 2014, In: Journal of Applied Physiology. 116, p. 192-203 12 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  77. Published

    Multiscale vision model for event detection and reconstruction in two-photon imaging data

    Brazhe, A., Mathiesen, C., Lind, Barbara Lykke, Rubin, A. & Lauritzen, Martin, Jul 2014, In: Neurophotonics. 1, 1, 011012.

    Research output: Contribution to journal › Journal article › Research › peer-review

  78. Published

    Mechanistic insight into the interaction of BLM helicase with intra-strand G-quadruplex structures

    Chatterjee, S., Zagelbaum, J., Savitsky, P., Sturzenegger, A., Huttner, D., Janscak, P., Hickson, Ian David, Gileadi, O. & Rothenberg, E., 24 Nov 2014, In: Nature Communications. 5, p. 1-12 12 p., 5556.

    Research output: Contribution to journal › Journal article › Research › peer-review

  79. Published

    Accuracy of MRI technique in measuring tendon cross-sectional area

    Couppé, Christian, Svensson, R. B., Elbrønd (Bibs), Vibeke Sødring, Hansen, P., Kjær, Michael & Magnusson, Stig Peter, 2014, In: Clinical Physiology and Functional Imaging. 34, 3, p. 237-241 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  80. Published

    Life-long endurance running is associated with reduced glycation and mechanical stress in connective tissue

    Couppé, Christian, Svensson, R. B., Grosset, J., Kovanen, V., Nielsen, R. H., Olsen, M. R., Larsen, J. O., Praet, S. F. E., Skovgaard, D., Hansen, M., Aagaard, P., Kjær, Michael & Magnusson, Stig Peter, Aug 2014, In: Age (Dordrecht, Netherlands). 36, 4, p. 1-19 19 p., 9665.

    Research output: Contribution to journal › Journal article › Research › peer-review

  81. Published

    Functional implications of the p.Cys680Arg mutation in the MLH1 mismatch repair protein

    Dominguez-Valentin, M., Drost, M., Therkildsen, C., Rambech, E., Ehrencrona, H., Angleys, M., Lau Hansen, T., de Wind, N., Nilbert, Mef Christina & Rasmussen, Lene Juel, Jul 2014, In: Molecular Genetics & Genomic Medicine. 2, 4, p. 352-355 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  82. Published

    Capillary pericytes regulate cerebral blood flow in health and disease

    Hall, C. N., Reynell, C., Gesslein, B., Hamilton, N. B., Mishra, A., Sutherland, B. A., O'Farrell, F. M., Buchan, A. M., Lauritzen, Martin & Attwell, D., Apr 2014, In: Nature. 508, 7494, p. 55-60 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  83. Published

    Basic Components of Connective Tissues and Extracellular Matrix: Elastin, Fibrillin, Fibulins, Fibrinogen, Fibronectin, Laminin, Tenascins and Thrombospondins

    Halper, J. & Kjær, Michael, 2014, Progress in Heritable Soft Connective Tissue Diseases. Vol. 802. p. 31-47 17 p. (Advances in Experimental Medicine and Biology).

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  84. Published

    Influence of Sex and Estrogen on Musculotendinous Protein Turnover at Rest and After Exercise

    Hansen, M. & Kjær, Michael, 2014, In: Exercise and Sport Sciences Reviews. 42, 4, p. 183–192 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  85. Published

    Subclinical cognitive decline in middle-age is associated with reduced task-induced deactivation of the brain's default mode network

    Hansen, N. L., Lauritzen, Martin, Mortensen, Erik Lykke, Osler, Merete, Avlund, K., Fagerlund, Birgitte & Rostrup, E., Sep 2014, In: Human Brain Mapping. 35, 9, p. 4488-98 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  86. Published

    The single-biopsy approach in determining protein synthesis in human slow-turning-over tissue: use of flood-primed, continuous infusion of amino acid tracer

    Holm, L., Reitelseder, S., Dideriksen, K., Nielsen, R. H., Bülow, J. & Kjær, Michael, 23 Apr 2014, In: American Journal of Physiology: Endocrinology and Metabolism. 306, 11, p. E1330-39 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  87. Published

    Aging impairs the recovery in mechanical muscle function following 4 days of disuse

    Hvid, L. G., Suetta, Charlotte, Nielsen, J., Jensen, M. M., Frandsen, U., Ørtenblad, N., Kjær, Michael & Aagaard, P., Apr 2014, In: Experimental Gerontology. 52, p. 1-8 8 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  88. Published

    The role of RecQ helicases in non-homologous end-joining

    Keijzers, G., Maynard, S., Shamanna, R. A., Rasmussen, Lene Juel, Croteau, D. L. & Bohr, Vilhelm, Nov 2014, In: Critical Reviews in Biochemistry and Molecular Biology. 49, 6, p. 463-472 10 p.

    Research output: Contribution to journal › Review › Research › peer-review

  89. Published

    Eccentric exercise: acute and chronic effects on healthy and diseased tendons

    Kjær, Michael & Heinemeier, K. M., 1 Jun 2014, In: Journal of Applied Physiology. 116, 11, p. 1435-1438 4 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  90. Published

    The Escherichia coli Tus-Ter replication fork barrier causes site-specific DNA replication perturbation in yeast

    Larsen, N. B., Sass, E., Suski, C., Mankouri, H. W. & Hickson, Ian David, 2014, In: Nature Communications. 5, p. 1-10 10 p., 3574.

    Research output: Contribution to journal › Journal article › Research › peer-review

  91. Published

    Tus-Ter as a tool to study site-specific DNA replication perturbation in eukaryotes

    Larsen, N. B., Hickson, Ian David & Mankouri, H. W., 1 Oct 2014, In: Cell Cycle. 13, 19, p. 2994-8 5 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  92. Published

    Myopati som årsag til akut opstået tetraparese på en intensivafdeling

    Lindqvist, J. K., Lauritzen, Martin, Laursen, H. & Benedek, K., 28 Jul 2014, In: Ugeskrift for Laeger. 176, 31, p. 2-3 2 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  93. Published

    The origins and processing of ultra fine anaphase DNA bridges

    Liu, Ying, Nielsen, Christian Friberg, Yao, Q. & Hickson, Ian David, 30 Apr 2014, In: Current Opinion in Genetics & Development. 26C, p. 1-5 5 p.

    Research output: Contribution to journal › Review › Research › peer-review

  94. Published

    Differential satellite cell density of type I and II fibres with lifelong endurance running in old men

    Mackey, Abigail, Karlsen, Anders, Couppé, Christian, Mikkelsen, U. R., Nielsen, R. H., Magnusson, Stig Peter & Kjær, Michael, Mar 2014, In: Acta Physiologica (Print). 210, 3, p. 612-27 16 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  95. Published

    Introducing the hypothome: a way to integrate predicted proteins in interactomes

    Desler, Claus, Zambach, S., Suravajhala, P. & Rasmussen, Lene Juel, 2014, In: International Journal of Bioinformatics Research and Applications. 10, 6, p. 647-52 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  96. Published

    Mitochondria in biology and medicine--2012

    Desler, Claus & Rasmussen, Lene Juel, May 2014, In: Mitochondrion. 16, p. 2-6 5 p.

    Research output: Contribution to journal › Review › Research › peer-review

  97. Published

    Lactate transport and receptor actions in cerebral malaria

    Mariga, S. T., Kolko, Miriam, Gjedde, Albert & Bergersen, L. H., 2014, In: Frontiers in Neuroscience. 8, p. 1-6 6 p., 2.

    Research output: Contribution to journal › Journal article › Research › peer-review

  98. Published

    Integrated Measurements of Electrical Activity, Oxygen Tension, Blood Flow, and Ca2+ -Signaling in Rodents In Vivo

    Mathiesen, C., Thomsen, K. & Lauritzen, Martin, 2014, Brain Energy Metabolism. Hirrlinger, J. & Waagepetersen, H. S. (eds.). p. 243-264 22 p.

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Education › peer-review

  99. Published

    Integrated measurements of electrical activity, Oxygen tension, Blood flow, And Ca2+-Signaling in rodents in vivo

    Mathiesen, C., Thomsen, Kirsten Joan & Lauritzen, Martin, 1 Jan 2014, Brain Energy Metabolism. Vol. 90. p. 243-264 22 p. (Neuromethods).

    Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

  100. Published

    Structure-specific endonucleases: guardians of fragile site stability

    Minocherhomji, S. & Hickson, Ian David, May 2014, In: Trends in Cell Biology. 24, 5, p. 321-327 7 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  101. Published

    Functional adaptation of tendon and skeletal muscle to resistance training in three patients with genetically verified classic Ehlers Danlos Syndrome

    Møller, M. B., Kjær, Michael, Svensson, R. B., Andersen, J. L., Magnusson, Stig Peter & Nielsen, R. H., 2014, In: M.L.T.J. Muscles, Ligaments and Tendons Journal. 4, 3, p. 315-323 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  102. Published

    Regulation of gene expression by the BLM helicase correlates with the presence of G-quadruplex DNA motifs

    Nguyen, G. H., Tang, W., Robles, A. I., Beyer, R. P., Gray, L. T., Welsh, J. A., Schetter, A. J., Kumamoto, K., Wang, X. W., Hickson, Ian David, Maizels, N., Monnat, R. J. & Harris, C. C., 8 Jul 2014, In: Proceedings of the National Academy of Sciences of the United States of America. 111, 27, p. 9905-10 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  103. Published

    Chronic alterations in growth hormone/insulin-like growth factor-I signaling lead to changes in mouse tendon structure

    Nielsen, R. H., Clausen, N. M., Schjerling, Peter, Larsen, J. O., Martinussen, Torben, List, E. O., Kopchick, J. J., Kjær, Michael & Heinemeier, K. M., Feb 2014, In: Matrix Biology. 34, p. 96-104 9 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

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