Morten Scheibye-Knudsen
Associate Professor
Molecular Aging Program
Blegdamsvej 3
2200 København N.
Member of:
Web: Center for Healthy Aging
Web Track 1: Modifiable pathways of damage and repair in aging
- 2014
Contribution of defective mitophagy to the neurodegeneration in DNA repair-deficient disorders
Scheibye-Knudsen, Morten, Fang, E. F., Croteau, D. L. & Bohr, Vilhelm, 2014, In: Autophagy. 10, 8, p. 1468-1469 2 p.Research output: Contribution to journal › Journal article › Research › peer-review
Di-(2-ethylhexyl) phthalate inhibits DNA replication leading to hyperPARylation, SIRT1 attenuation, and mitochondrial dysfunction in the testis
Li, X., Fang, E. F., Scheibye-Knudsen, Morten, Cui, H., Qiu, L., Li, J., He, Y., Huang, J., Bohr, Vilhelm, Ng, T. B. & Guo, H., 2014, In: Scientific Reports. 4, 6434.Research output: Contribution to journal › Journal article › Research › peer-review
SRT2104 extends survival of male mice on a standard diet and preserves bone and muscle mass
Mercken, E. M., Mitchell, S. J., Martin-Montalvo, A., Minor, R. K., Almeida, M., Gomes, A. P., Scheibye-Knudsen, M., Palacios, H. H., Licata, J. J., Zhang, Y., Becker, K. G., Khraiwesh, H., González-Reyes, J. A., Villalba, J. M., Baur, J. A., Elliott, P., Westphal, C., Vlasuk, G. P., Ellis, J. L., Sinclair, D. A. & 2 others, , 1 Oct 2014, In: Aging Cell. 13, 5, p. 787-796 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A high-fat diet and NAD+ activate sirt1 to rescue premature aging in cockayne syndrome
Scheibye-Knudsen, M., Mitchell, S. J., Fang, E. F., Iyama, T., Ward, T., Wang, J., Dunn, C. A., Singh, N., Veith, S., Hasan-Olive, M. M., Mangerich, A., Wilson, M. A., Mattson, M. P., Bergersen, L. H., Cogger, V. C., Warren, A., Le Couteur, D. G., Moaddel, R., Wilson, D. M., Croteau, D. L. & 2 others, , 4 Nov 2014, In: Cell Metabolism. 20, 5, p. 840-855 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2015
Animal models of aging research: implications for human aging and age-related diseases
Mitchell, S. J., Scheibye-Knudsen, Morten, Longo, D. L. & de Cabo, R., 2015, In: Annual Review of Animal Biosciences. 3, p. 283-303 21 p.Research output: Contribution to journal › Journal article › Research › peer-review
Loss of NEIL1 causes defects in olfactory function in mice
Canugovi, C., Misiak, M., Scheibye-Knudsen, Morten, Croteau, D. L., Mattson, M. P. & Bohr, Vilhelm, 1 Feb 2015, In: Neurobiology of Aging. 36, 2, p. 1007-1012 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
Nourishing the aging brain
Scheibye-Knudsen, Morten, 1 Mar 2015, In: The Scientist. 29, 3Research output: Contribution to journal › Journal article › Communication
Protecting the mitochondrial powerhouse
Scheibye-Knudsen, Morten, Fang, E. F., Croteau, D. L., Wilson, D. M. & Bohr, Vilhelm, 1 Mar 2015, In: Trends in Cell Biology. 25, 3, p. 158-170 13 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
A novel method for determining human ex vivo submaximal skeletal muscle mitochondrial function
Hey-Mogensen, M., Gram, M., Jensen, M. B., Lund, M. T., Hansen, C. N., Scheibye-Knudsen, Morten, Bohr, Vilhelm & Dela, Flemming, 1 Sep 2015, In: The Journal of Physiology. 593, 17, p. 3991-4010 20 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
DNA Damage, DNA Repair, Aging, and Neurodegeneration
Maynard, S., Fang, E. F., Scheibye-Knudsen, Morten, Croteau, D. L. & Bohr, Vilhelm, Oct 2015, In: Cold Spring Harbor Perspectives in Medicine. 5, 10, a025130.Research output: Contribution to journal › Journal article › Research › peer-review
A research agenda for aging in China in the 21st century
Fang, E. F., Scheibye-Knudsen, Morten, Jahn, H. J., Li, J., Ling, L., Guo, H., Zhu, X., Preedy, V., Lu, H., Bohr, Vilhelm, Chan, W. Y., Liu, Y. & Ng, T. B., Nov 2015, In: Ageing Research Reviews. 24, Pt B, p. 197-205 9 p.Research output: Contribution to journal › Review › Research › peer-review
- 2016
- Published
Neurodegeneration in accelerated aging
Scheibye-Knudsen, Morten, 2016, 190 p.Research output: Book/Report › Doctoral thesis › Research
Nuclear DNA damage signalling to mitochondria in ageing
Fang, E. F., Scheibye-Knudsen, Morten, Chua, K. F., Mattson, M. P., Croteau, D. L. & Bohr, Vilhelm, May 2016, In: Nature Reviews. Molecular Cell Biology. 17, 5, p. 308-321 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effects of Sex, Strain, and Energy Intake on Hallmarks of Aging in Mice
Mitchell, S. J., Madrigal-Matute, J., Scheibye-Knudsen, M., Fang, E., Aon, M., Gonzalez-Reyes, J. A., Cortassa, S., Kaushik, S., Gonzalez-Freire, M., Patel, B., Wahl, D., Ali, A., Calvo-Rubio, M., Buron, M. I., Guiterrez, V., Ward, T. M., Palacios, H. H., Cai, H., Frederick, D. W., Hine, C. & 27 others, , 14 Jun 2016, In: Cell Metabolism. 23, 6, p. 1093-1112Research output: Contribution to journal › Journal article › Research › peer-review
- Published
NAD(+) Replenishment Improves Lifespan and Healthspan in Ataxia Telangiectasia Models via Mitophagy and DNA Repair
Fang, E. F., Kassahun, H., Croteau, D. L., Scheibye-Knudsen, M., Marosi, K., Lu, H., Shamanna, R. A., Kalyanasundaram, S., Bollineni, R. C., Wilson, M. A., Iser, W. B., Wollman, B. N., Morevati, M., Li, J., Kerr, J. S., Lu, Q., Waltz, T. B., Tian, J., Sinclair, D. A., Mattson, M. P. & 2 others, , 11 Oct 2016, In: Cell Metabolism. 24, 4, p. 566-581 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Neurodegeneration in Accelerated Aging
Scheibye-Knudsen, Morten, Nov 2016, In: Danish Medical Journal. 63, 11, 21 p., B5308.Research output: Contribution to journal › Review › Research › peer-review
- Published
Cockayne syndrome group A and B proteins converge on transcription-linked resolution of non-B DNA
Scheibye-Knudsen, M., Tseng, A., Jensen, M. B., Scheibye-Alsing, K., Fang, E. F., Iyama, T., Bharti, S. K., Marosi, K., Froetscher, L., Kassahun, H., Eckley, D. M., Maul, R. W., Bastian, P., De, S., Ghosh, S., Nilsen, H., Goldberg, I. G., Mattson, M. P., Wilson, D. M. . III., Brosh, R. M. . J. & 2 others, , 1 Nov 2016, In: National Academy of Sciences. Proceedings. 113, 44, p. 12502-12507Research output: Contribution to journal › Journal article › Research › peer-review
- Published
3-Hydroxybutyrate regulates energy metabolism and induces BDNF expression in cerebral cortical neurons
Marosi, K., Kim, S. W., Moehl, K., Scheibye-Knudsen, Morten, Cheng, A., Cutler, R., Camandola, S. & Mattson, M. P., Dec 2016, In: Journal of Neurochemistry. 139, 5, p. 769-781 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A ketogenic diet accelerates neurodegeneration in mice with induced mitochondrial DNA toxicity in the forebrain
Lauritzen, K. H., Hasan-Olive, M. M., Regnell, C. E., Kleppa, L., Scheibye-Knudsen, Morten, Gjedde, Albert, Klungland, A., Bohr, Vilhelm, Storm-Mathisen, J. & Bergersen, L. H., Dec 2016, In: Neurobiology of Aging. 48, p. 34-47Research output: Contribution to journal › Journal article › Research › peer-review
- 2017
- Published
Cockayne syndrome: Clinical features, model systems and pathways
Karikkineth, A. C., Scheibye-Knudsen, Morten, Fivenson, E., Croteau, D. L. & Bohr, Vilhelm, 2017, In: Ageing Research Reviews. 33, p. 3-17Research output: Contribution to journal › Review › Research › peer-review
- Published
Mitophagy in neurodegeneration and aging
Fivenson, E. M., Lautrup, S., Sun, N., Scheibye-Knudsen, Morten, Stevnsner, T., Nilsen, H., Bohr, Vilhelm & Fang, E. F., 2017, In: Neurochemistry International. 109, p. 202-209Research output: Contribution to journal › Review › Research › peer-review
- Published
Tomatidine enhances lifespan and healthspan in C. elegans through mitophagy induction via the SKN-1/Nrf2 pathway
Fang, E. F., Waltz, T. B., Kassahun, H., Lu, Q., Kerr, J. S., Morevati, M., Fivenson, E. M., Wollman, B. N., Marosi, K., Wilson, M. A., Iser, W. B., Eckley, D. M., Zhang, Y., Lehrmann, E., Goldberg, I. G., Scheibye-Knudsen, Morten, Mattson, M. P., Nilsen, H., Bohr, Vilhelm & Becker, K. G., 2017, In: Scientific Reports. 7, 46208.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Monogenic diseases of DNA repair
Keijzers, G., Bakula, Daniela Janina & Scheibye-Knudsen, Morten, Nov 2017, In: New England Journal of Medicine. 377, 19, p. 1868-1876 9 p.Research output: Contribution to journal › Review › Research › peer-review
- 2018
- Published
Aging and drug discovery
Bakula, D., Aliper, A. M., Mamoshina, P., Petr, M. A., Teklu, A., Baur, J. A., Campisi, J., Ewald, C. Y., Georgievskaya, A., Gladyshev, V. N., Kovalchuk, O., Lamming, D. W., Luijsterburg, M. S., Martín-Montalvo, A., Maudsley, S., Mkrtchyan, G. V., Moskalev, A., Jay Olshansky, S., Ozerov, I. V., Pickett, A. & 3 others, , 2018, In: Aging. 10, 11, p. 3079-3088 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Population specific biomarkers of human aging: A big data study using South Korean, Canadian, and Eastern European patient populations
Mamoshina, P., Kochetov, K., Putin, E., Cortese, F., Aliper, A., Lee, W. S., Ahn, S. M., Uhn, L., Skjodt, N., Kovalchuk, O., Scheibye-Knudsen, Morten & Zhavoronkov, A., 2018, In: Journals of Gerontology - Series A Biological Sciences and Medical Sciences. 73, 11, p. 1482-1490 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 144763346
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Artificial intelligence for aging and longevity research: Recent advances and perspectives
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A defined human aging phenome
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Tomatidine enhances lifespan and healthspan in C. elegans through mitophagy induction via the SKN-1/Nrf2 pathway
Research output: Contribution to journal › Journal article › Research › peer-review
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