Morten Scheibye-Knudsen

Morten Scheibye-Knudsen

Associate Professor

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  1. Published

    A defined human aging phenome

    Andreassen, Søren Norge, Ben Ezra, Michael & Scheibye-Knudsen, Morten, 2019, In: Aging. 11, 15, p. 5786-5806 21 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  2. Published

    Latest advances in aging research and drug discovery

    Bakula, D., Ablasser, A., Aguzzi, A., Antebi, A., Barzilai, N., Bittner, M. I., Jensen, M. B., Calkhoven, C. F., Chen, D., de Grey, A. D. N. J., Feige, J. N., Georgievskaya, A., Gladyshev, V. N., Golato, T., Gudkov, A. V., Hoppe, T., Kaeberlein, M., Katajisto, P., Kennedy, B. K., Lal, U. & 10 others, Martin-Villalba, A., Moskalev, A. A., Ozerov, I., Petr, Michael Angelo, Reason, Rubinsztein, D. C., Tyshkovskiy, A., Vanhaelen, Q., Zhavoronkov, A. & Scheibye-Knudsen, Morten, 2019, In: Aging. 11, 22, p. 9971-9981 11 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  3. Published

    Aging and drug discovery

    Bakula, D., Aliper, A. M., Mamoshina, P., Petr, M. A., Teklu, A., Baur, J. A., Campisi, J., Ewald, C. Y., Georgievskaya, A., Gladyshev, V. N., Kovalchuk, O., Lamming, D. W., Luijsterburg, M. S., Martín-Montalvo, A., Maudsley, S., Mkrtchyan, G. V., Moskalev, A., Jay Olshansky, S., Ozerov, I. V., Pickett, A. & 3 others, Ristow, M., Zhavoronkov, A. & Scheibye-Knudsen, Morten, 2018, In: Aging. 10, 11, p. 3079-3088 10 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  4. Published

    MitophAging: Mitophagy in Aging and Disease

    Bakula, Daniela Janina & Scheibye-Knudsen, Morten, 2020, In: Frontiers in Cell and Developmental Biology. 8, 16 p., 239.

    Research output: Contribution to journal › Review › Research › peer-review

  5. Published

    Longevity medicine: upskilling the physicians of tomorrow

    Bischof, E., Scheibye-Knudsen, Morten, Siow, R. & Moskalev, A., 2021, In: The Lancet Healthy Longevity. 2, 4, p. e187-e188

    Research output: Contribution to journal › Comment/debate › Research › peer-review

  6. Published

    A novel splice variant of Elp3/Kat9 regulates mitochondrial tRNA modification and function

    Boutoual, R., Jo, H., Heckenbach, Indra John, Tiwari, R., Kasler, H., Lerner, C. A., Shah, S., Schilling, B., Calvanese, V., Rardin, M. J., Scheibye-Knudsen, Morten & Verdin, E., 2022, In: Scientific Reports. 12, 14804.

    Research output: Contribution to journal › Journal article › Research › peer-review

  7. Loss of NEIL1 causes defects in olfactory function in mice

    Canugovi, C., Misiak, M., Scheibye-Knudsen, Morten, Croteau, D. L., Mattson, M. P. & Bohr, Vilhelm, 1 Feb 2015, In: Neurobiology of Aging. 36, 2, p. 1007-1012 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  8. Published

    Vive la radiorésistance! Converging research in radiobiology and biogerontology to enhance human radioresistance for deep space exploration and colonization

    Cortese, F., Klokov, D., Osipov, A., Stefaniak, J., Moskalev, A., Schastnaya, J., Cantor, C., Aliper, A., Mamoshina, P., Ushakov, I., Sapetsky, A., Vanhaelen, Q., Alchinova, I., Karganov, M., Kovalchuk, O., Wilkins, R., Shtemberg, A., Moreels, M., Baatout, S., Izumchenko, E. & 10 others, de Magalhães, J. P., Artemov, A. V., Costes, S. V., Beheshti, A., Mao, X. W., Pecaut, M. J., Kaminskiy, D., Ozerov, I. V., Scheibye-Knudsen, Morten & Zhavoronkov, A., 2018, In: OncoTarget. 9, 18, p. 14692-14722 31 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  9. Published

    Senescent cells promote tissue NAD+ decline during ageing via the activation of CD38+ macrophages

    Covarrubias, A. J., Kale, A., Perrone, R., Lopez-Dominguez, J. A., Pisco, A. O., Kasler, H. G., Schmidt, M. S., Heckenbach, I., Kwok, R., Wiley, C. D., Wong, H. S., Gibbs, E., Iyer, S. S., Basisty, N., Wu, Q., Kim, I. J., Silva, E., Vitangcol, K., Shin, K. O., Lee, Y. M. & 11 others, Riley, R., Ben-Sahra, I., Ott, M., Schilling, B., Scheibye-Knudsen, Morten, Ishihara, K., Quake, S. R., Newman, J., Brenner, C., Campisi, J. & Verdin, E., 2020, In: Nature Metabolism. 2, 11, p. 1265-1283 19 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  10. Published

    EX-vivo whole blood stimulation with A2E does not elicit an inflammatory cytokine response in patients with age-related macular degeneration

    Durhuus, J. A., Rozing, Maarten Pieter, Nielsen, M. K., Molbech, C. R., Keijzers, G., Scheibye-Knudsen, Morten, Rasmussen, Lene Juel, Westendorp, Rudi GJ & Sørensen, Torben Lykke, 2021, In: Scientific Reports. 11, 1, 8226.

    Research output: Contribution to journal › Journal article › Research › peer-review

  11. Emerging Antitumor Activities of the Bitter Melon (Momordica charantia)

    Fang, E. F., Froetscher, L., Scheibye-Knudsen, Morten, Bohr, Vilhelm, Wong, J. H. & Ng, T. B., 2019, In: Current Protein and Peptide Science. 20, 3, p. 296-301 6 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  12. Nuclear DNA damage signalling to mitochondria in ageing

    Fang, E. F., Scheibye-Knudsen, Morten, Chua, K. F., Mattson, M. P., Croteau, D. L. & Bohr, Vilhelm, May 2016, In: Nature Reviews. Molecular Cell Biology. 17, 5, p. 308-321 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  13. Published

    Tomatidine enhances lifespan and healthspan in C. elegans through mitophagy induction via the SKN-1/Nrf2 pathway

    Fang, E. F., Waltz, T. B., Kassahun, H., Lu, Q., Kerr, J. S., Morevati, M., Fivenson, E. M., Wollman, B. N., Marosi, K., Wilson, M. A., Iser, W. B., Eckley, D. M., Zhang, Y., Lehrmann, E., Goldberg, I. G., Scheibye-Knudsen, Morten, Mattson, M. P., Nilsen, H., Bohr, Vilhelm & Becker, K. G., 2017, In: Scientific Reports. 7, 46208.

    Research output: Contribution to journal › Journal article › Research › peer-review

  14. A research agenda for aging in China in the 21st century

    Fang, E. F., Scheibye-Knudsen, Morten, Jahn, H. J., Li, J., Ling, L., Guo, H., Zhu, X., Preedy, V., Lu, H., Bohr, Vilhelm, Chan, W. Y., Liu, Y. & Ng, T. B., Nov 2015, In: Ageing Research Reviews. 24, Pt B, p. 197-205 9 p.

    Research output: Contribution to journal › Review › Research › peer-review

  15. Published

    NAD(+) Replenishment Improves Lifespan and Healthspan in Ataxia Telangiectasia Models via Mitophagy and DNA Repair

    Fang, E. F., Kassahun, H., Croteau, D. L., Scheibye-Knudsen, M., Marosi, K., Lu, H., Shamanna, R. A., Kalyanasundaram, S., Bollineni, R. C., Wilson, M. A., Iser, W. B., Wollman, B. N., Morevati, M., Li, J., Kerr, J. S., Lu, Q., Waltz, T. B., Tian, J., Sinclair, D. A., Mattson, M. P. & 2 others, Nilsen, H. & Bohr, Vilhelm, 11 Oct 2016, In: Cell Metabolism. 24, 4, p. 566-581 16 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  16. Published

    Mitophagy in neurodegeneration and aging

    Fivenson, E. M., Lautrup, S., Sun, N., Scheibye-Knudsen, Morten, Stevnsner, T., Nilsen, H., Bohr, Vilhelm & Fang, E. F., 2017, In: Neurochemistry International. 109, p. 202-209

    Research output: Contribution to journal › Review › Research › peer-review

  17. Published

    Tracking the dynamics of cellular senescence

    Heckenbach, Indra John & Scheibye-Knudsen, Morten, 2023, In: Aging. 15, 9, p. 3219-3220 2 p.

    Research output: Contribution to journal › Editorial › Research › peer-review

  18. Published

    Nuclear morphology is a deep learning biomarker of cellular senescence

    Heckenbach, Indra John, Mkrtchyan, Garik, Ben Ezra, Michael, Bakula, Daniela Janina, Madsen, Jakob Sture, Nielsen, M. H., Oró, D., Osborne, Brenna, Covarrubias, A. J., Idda, M. L., Gorospe, M., Mortensen, Laust Hvas, Verdin, E., Westendorp, Rudi GJ & Scheibye-Knudsen, Morten, 2022, In: Nature Aging. 2, 8, p. 742-755 14 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  19. Published

    Reduction of lamin B receptor levels by miR-340-5p disrupts chromatin, promotes cell senescence and enhances senolysis

    Herman, A. B., Anerillas, C., Harris, S. C., Munk, R., Martindale, J. L., Yang, X., Mazan-Mamczarz, K., Zhang, Y., Heckenbach, Indra John, Scheibye-Knudsen, Morten, De, S., Sen, P., Abdelmohsen, K. & Gorospe, M., 2021, In: Nucleic Acids Research. 49, 13, p. 7389-7405 17 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  20. Published

    A novel method for determining human ex vivo submaximal skeletal muscle mitochondrial function

    Hey-Mogensen, M., Gram, M., Jensen, M. B., Lund, M. T., Hansen, C. N., Scheibye-Knudsen, Morten, Bohr, Vilhelm & Dela, Flemming, 1 Sep 2015, In: The Journal of Physiology. 593, 17, p. 3991-4010 20 p.

    Research output: Contribution to journal › Journal article › Research › peer-review

  21. Published

    Cockayne syndrome: Clinical features, model systems and pathways

    Karikkineth, A. C., Scheibye-Knudsen, Morten, Fivenson, E., Croteau, D. L. & Bohr, Vilhelm, 2017, In: Ageing Research Reviews. 33, p. 3-17

    Research output: Contribution to journal › Review › Research › peer-review

  22. Published

    The authors reply

    Keijzers, G., Bakula, Daniela Janina & Scheibye-Knudsen, Morten, 1 Feb 2018, In: New England Journal of Medicine. 378, 5, p. 491-492 2 p.

    Research output: Contribution to journal › Comment/debate › Research › peer-review

  23. Published

    Monogenic diseases of DNA repair

    Keijzers, G., Bakula, Daniela Janina & Scheibye-Knudsen, Morten, Nov 2017, In: New England Journal of Medicine. 377, 19, p. 1868-1876 9 p.

    Research output: Contribution to journal › Review › Research › peer-review

  24. Published

    Human exonuclease 1 (EXO1) regulatory functions in DNA replication with putative roles in cancer

    Keijzers, G., Bakula, Daniela Janina, Petr, Michael Angelo, Madsen, N. G. K., Teklu, Amanuel Abraha, Mkrtchyan, Garik, Osborne, Brenna & Scheibye-Knudsen, Morten, 2019, In: International Journal of Molecular Sciences . 20, 1, 15 p., 74.

    Research output: Contribution to journal › Review › Research › peer-review

  25. Published

    Monogenic Diseases of DNA Repair

    Keijzers, G., Bakula, Daniela Janina & Scheibye-Knudsen, Morten, 1 Feb 2018, In: The New England Journal of Medicine. 378, 5, p. 491-492 2 p.

    Research output: Contribution to journal › Comment/debate › Research › peer-review

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