Brenna Osborne

Brenna Osborne

Assistant Professor, Guest Researcher

Member of:

    ORCID: 0000-0002-0197-3010

    Publication year:
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    11 - 20 out of 31Page size: 10
    1. 2019

    2. A novel small molecule that kills a subset of MLL-rearranged leukemia cells by inducing mitochondrial dysfunction

      Somers, K., Wen, V. W., Middlemiss, S. M. C., Osborne, B., Forgham, H., Jung, M., Karsa, M., Clifton, M., Bongers, A., Gao, J., Mayoh, C., Raoufi-Rad, N., Kusnadi, E. P., Hannan, K. M., Scott, D. A., Kwek, A., Liu, B., Flemming, C., Chudakova, D. A., Pandher, R. & 17 others, Failes, T. W., Lim, J., Angeli, A., Osterman, A. L., Imamura, T., Kees, U. R., Supuran, C. T., Pearson, R. B., Hannan, R. D., Davis, T. P., McCarroll, J., Kavallaris, M., Turner, N., Gudkov, A. V., Haber, M., Norris, M. D. & Henderson, M. J., 22 May 2019, In: Oncogene. 38, p. 3824–3842

      Research output: Contribution to journal › Journal article › Research › peer-review

    3. Erratum: Impairment of an Endothelial NAD+-H2S Signaling Network Is a Reversible Cause of Vascular Aging (Cell (2018) 173(1) (74–89.e20), (S0092867418301521) (10.1016/j.cell.2018.02.008))

      Das, A., Huang, G. X., Bonkowski, M. S., Longchamp, A., Li, C., Schultz, M. B., Kim, L. J., Osborne, B., Joshi, S., Lu, Y., Treviño-Villarreal, J. H., Kang, M. J., Hung, T. T., Lee, B., Williams, E. O., Igarashi, M., Mitchell, J. R., Wu, L. E., Turner, N., Arany, Z. & 2 others, Guarente, L. & Sinclair, D. A., 7 Feb 2019, In: Cell. 176, 4, p. 944-945 2 p.

      Research output: Contribution to journal › Comment/debate › Research › peer-review

    4. Published

      Human exonuclease 1 (EXO1) regulatory functions in DNA replication with putative roles in cancer

      Keijzers, G., Bakula, Daniela Janina, Petr, Michael Angelo, Madsen, N. G. K., Teklu, Amanuel Abraha, Mkrtchyan, Garik, Osborne, Brenna & Scheibye-Knudsen, Morten, 2019, In: International Journal of Molecular Sciences . 20, 1, 15 p., 74.

      Research output: Contribution to journal › Review › Research › peer-review

    5. Published

      Impact of lifestyle and clinical interventions on mitochondrial function in obesity and type 2 diabetes

      Osborne, Brenna, Brandon, A. E., Smith, G. C. & Turner, N., 2019, Mitochondria in Obesity and Type 2 Diabetes: Comprehensive Review on Mitochondrial Functioning and Involvement in Metabolic Diseases. Academic Press, p. 367-397 31 p.

      Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review

    6. Regulation of mitochondrial metabolism in murine skeletal muscle by the medium-chain fatty acid receptor Gpr84

      Montgomery, M. K., Osborne, Brenna, Brandon, A. E., O'Reilly, L., Fiveash, C. E., Brown, S. H. J., Wilkins, B. P., Samsudeen, A., Yu, J., Devanapalli, B., Hertzog, A., Tolun, A. A., Kavanagh, T., Cooper, A. A., Mitchell, T. W., Biden, T. J., Smith, N. J., Cooney, G. J. & Turner, N., 2019, In: FASEB Journal. 33, 11, p. 12264-12276

      Research output: Contribution to journal › Journal article › Research › peer-review

    7. 2018

    8. A selective inhibitor of ceramide synthase 1 reveals a novel role in fat metabolism

      Turner, N., Lim, X. Y., Toop, H. D., Osborne, B., Brandon, A. E., Taylor, E. N., Fiveash, C. E., Govindaraju, H., Teo, J. D., McEwen, H. P., Couttas, T. A., Butler, S. M., Das, A., Kowalski, G. M., Bruce, C. R., Hoehn, K. L., Fath, T., Schmitz-Peiffer, C., Cooney, G. J., Montgomery, M. K. & 2 others, Morris, J. C. & Don, A. S., Dec 2018, In: Nature Communications. 9, 3165.

      Research output: Contribution to journal › Journal article › Research › peer-review

    9. Protein hypoacylation induced by Sirt5 overexpression has minimal metabolic effect in mice

      Bentley, N. L., Fiveash, C. E., Osborne, Brenna, Quek, L., Ogura, M., Inagaki, N., Cooney, G. J., Polly, P., Montgomery, M. K. & Turner, N., Jul 2018, In: Biochemical and Biophysical Research Communications. 503, 3, p. 1349-1355

      Research output: Contribution to journal › Journal article › Research › peer-review

    10. Impairment of an Endothelial NAD+-H2S Signaling Network Is a Reversible Cause of Vascular Aging

      Das, A., Huang, G. X., Bonkowski, M. S., Longchamp, A., Li, C., Schultz, M. B., Kim, L-J., Osborne, B., Joshi, S., Lu, Y., Treviño-Villarreal, J. H., Kang, M-J., Hung, T., Lee, B., Williams, E. O., Igarashi, M., Mitchell, J. R., Wu, L. E., Turner, N., Arany, Z. & 2 others, Guarente, L. & Sinclair, D. A., 2018, In: Cell. 173, 1, p. 74-89 16 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    11. 2017

    12. NAD+: A key metabolic regulator with great therapeutic potential

      Sultani, G., Samsudeen, A. F., Osborne, Brenna & Turner, N., 2017, In: Journal of Neuroendocrinology. 29, 10, e12508.

      Research output: Contribution to journal › Review › Research › peer-review

    13. Pathways of Acetyl-CoA Metabolism Involved in the Reversal of Palmitate-Induced Glucose Production by Metformin and Salicylate

      Hayward, B., Molero, J. C., Windmill, K., Sanigorski, A., Weir, J., McRae, N. L., Aston-Mourney, K., Osborne, Brenna, Liao, B., Walder, K. R., Meikle, P. J., Konstantopoulos, N. & Schmitz-Peiffer, C., 2017, In: Experimental and Clinical Endocrinology and Diabetes. 124, 10, p. 602-612 11 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

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