Niklas Rye Jørgensen

Niklas Rye Jørgensen

Clinical Professor

Member of:

  • Clinical Biochemistry


  1. 2018
  2. Published

    The combined effect of Parathyroid hormone (1-34) and whole-body Vibration exercise in the treatment of OSteoporosis (PaVOS)- study protocol for a randomized controlled trial

    Jepsen, D. B., Ryg, J., Jørgensen, Niklas Rye, Hansen, S. & Masud, T., 2018, In: Trials. 19, 9 p., 186.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. 2017
  4. Published

    The role of the P2X7 receptor on bone loss in a mouse model of inflammation-mediated osteoporosis

    Kvist, T. M., Syberg, S., Petersen, S., Ding, M., Jørgensen, Niklas Rye & Schwarz, Peter, Dec 2017, In: Bone Reports. 7, p. 145-151 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Synchrotron radiation μCT and histology evaluation of bone-to-implant contact

    Neldam, C. A., Sporring, Jon, Rack, A., Lauridsen, T., Hauge, E. M., Jørgensen, H. L., Jørgensen, Niklas Rye, Feidenhans'l, Robert Krarup & Pinholt, E. M., Sep 2017, In: Journal of Cranio-Maxillofacial Surgery. 45, 9, p. 1448-1457 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    P2X7Rs are involved in cell death, growth and cellular signaling in primary human osteoblasts

    Agrawal, A., Henriksen, Z., Syberg, S., Petersen, S., Aslan, D., Solgaard, M., Nissen, N., Larsen, T. K., Schwarz, Peter, Steinberg, T. H. & Jørgensen, Niklas Rye, Feb 2017, In: Bone. 95, p. 91-101 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Bone structural changes after gastric bypass surgery evaluated by HR-pQCT: a two-year longitudinal study

    Shanbhogue, V. V., Støving, R. K., Frederiksen, K. H., Hanson, S., Brixen, K., Gram, J., Jørgensen, Niklas Rye & Hansen, S., 2017, In: European Journal of Endocrinology. 176, 6, p. 685-693

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Bone turnover is altered in transgenic rats overexpressing the P2Y2 purinergic receptor

    Ellegaard, M., Agca, C., Petersen, S., Agrawal, A., Kruse, L. S., Wang, N., Gartland, A., Jensen, J. B., Jørgensen, Niklas Rye & Agca, Y., 2017, In: Purinergic Signalling. 13, 4, p. 545-557

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Clinical usefulness of bone turnover marker concentrations in osteoporosis

    IFCC-IOF Working Group for Standardisation of Bone Marker Assays (WG-BMA), I. W. G. F. S. O. B. M. A. (., 2017, In: Clinica Chimica Acta. 467, p. 34-41

    Research output: Contribution to journalReviewResearchpeer-review

  10. Published

    Effect of whole-body vibration exercise in preventing falls and fractures: a systematic review and meta-analysis

    Jepsen, D. B., Thomsen, K., Hansen, S., Jørgensen, Niklas Rye, Masud, T. & Ryg, J., 2017, In: B M J Open. 7, 12, 15 p., e018342.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Evidence for the prevention of bone loss in elderly and old early non-metastatic breast cancer patients treated with aromatase inhibitors

    Gunmalm, V., Jørgensen, Niklas Rye, Abrahamsen, B. & Schwarz, Peter, 2017, In: European Geriatric Medicine. 8, 5-6, p. 408-412

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Hyperkalemia is Associated with Increased 30-Day Mortality in Hip Fracture Patients

    Norring-Agerskov, D., Madsen, C. M., Abrahamsen, B., Riis, T., Pedersen, Ole Birger Vesterager, Jørgensen, Niklas Rye, Bathum, L., Lauritzen, Jes Bruun & Jørgensen, H. L., 2017, In: Calcified Tissue International. 101, 1, p. 9-16

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Optimizing combination of vascular endothelial growth factor and mesenchymal stem cells on ectopic bone formation in SCID mice

    Dreyer, C. H., Kjaergaard, K., Ditzel, N., Jørgensen, Niklas Rye, Overgaard, Søren & Ding, M., 2017, In: Journal of Biomedical Materials Research. Part A. 105, 12, p. 3326-3332

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    P2Y12 Receptor Antagonist, Clopidogrel, Does Not Contribute to Risk of Osteoporotic Fractures in Stroke Patients

    Jørgensen, Niklas Rye, Schwarz, Peter, Iversen, Helle Klingenberg & Vestergaard, P., 2017, In: Frontiers in Pharmacology. 8, 8 p., 821.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Reliability of the Biochemical Bone Markers CTX and P1NP during a TNF-Inhibitor Treatment Cycle in Patients with Rheumatoid Arthritis

    Holmsted, K., Jørgensen, Niklas Rye & gjc556, gjc556, 2017, In: Arthritis & Rheumatology. 69, S10, 2 p., 2382.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  16. 2016
  17. Published

    Soluble urokinase plasminogen activator receptor (suPAR) is a novel, independent predictive marker of myocardial infarction in HIV-1-infected patients: a nested case-control study

    Rasmussen, L. J. H., Knudsen, A., Katzenstein, T. L., Gerstoft, Jan, Obel, Niels, Jørgensen, Niklas Rye, Kronborg, Gitte, Benfield, Thomas, Kjær, Andreas, Eugen-Olsen, J. & Lebech, Anne-Mette, May 2016, In: HIV Medicine. 17, 5, p. 350-7 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    New insights on pyrimidine signalling within the arterial vasculature: Different roles for P2Y2 and P2Y6 receptors in large and small coronary arteries of the mouse

    Haanes, K. A., Spray, S., Syberg, S., Jørgensen, Niklas Rye, Robaye, B., Boeynaems, J. & Edvinsson, L., Apr 2016, In: Journal of Molecular and Cellular Cardiology. 93, p. 1-11 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. 2015
  20. Published

    Bone Geometry, Volumetric Density, Microarchitecture, and Estimated Bone Strength Assessed by HR-pQCT in Adult Patients With Type 1 Diabetes Mellitus

    Shanbhogue, V. V., Hansen, S., Frost, M., Jørgensen, Niklas Rye, Hermann, A. P., Henriksen, J. E. & Brixen, K., Dec 2015, In: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. 30, 12, p. 2188-99 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    The Impact of Nocturnal Hypoglycemia on Sleep in Subjects With Type 2 Diabetes

    Jennum, Poul, Stender-Petersen, K., Rabøl, R., Jørgensen, Niklas Rye, Chu, P. & Madsbad, Sten, Nov 2015, In: Diabetes Care. 38, 11, p. 2151-7 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Application of high resolution synchrotron micro-CT radiation in dental implant osseointegration

    Neldam, C. A., Lauridsen, T., Rack, A., Lefolii, T. T., Jørgensen, Niklas Rye, Feidenhans'l, Robert Krarup & Pinholt, E. M., 1 Jun 2015, In: Journal of Cranio-Maxillofacial Surgery. 43, 5, p. 682-687 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Accelerated tumor progression in mice lacking the ATP receptor P2X7

    Adinolfi, E., Capece, M., Franceschini, A., Falzoni, S., Giuliani, A. L., Rotondo, A., Sarti, A. C., Bonora, M., Syberg, S., Corigliano, D., Pinton, P., Jørgensen, Niklas Rye, Abelli, L., Emionite, L., Raffaghello, L., Pistoia, V. & Di Virgilio, F., 15 Feb 2015, In: Cancer Research. 75, 4, p. 635-44 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Epidemiology of forearm fractures in adults in Denmark: national age- and gender-specific incidence rates, ratio of forearm to hip fractures, and extent of surgical fracture repair in inpatients and outpatients

    Abrahamsen, B., Jørgensen, Niklas Rye & Schwarz, Peter, Jan 2015, In: Osteoporosis international with other metabolic bone diseases. 26, 1, p. 67-76 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Effects of soccer vs swim training on bone formation in sedentary middle-aged women

    Mohr, M., Helge, Eva Wulff, Petersen, L. F., Lindenskov, A., Weihe, P., Mortensen, Jann, Jørgensen, Niklas Rye & Krustrup, P., 2015, In: European Journal of Applied Physiology. 115, 12, p. 2671-2679 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    G-protein mediated signaling pathways in myogenic responsiveness of mouse mesenteric artery

    Jensen, Lars Jørn, Joseph, P. D., Haanes, Kristian Agmund, Hansen, S. S., Jørgensen, Niklas Rye, Hansen, J. L. & Salomonsson, M., 2015, In: Microcirculation. 22, 7, p. 631 1 p., P119.

    Research output: Contribution to journalConference abstract in journalResearchpeer-review

  27. Published

    GLP-1 receptor agonist treatment increases bone formation and prevents bone loss in weight-reduced obese women

    Iepsen, E. P. W., Lundgren, J. R., Hartmann, Bolette, Pedersen, Oluf Borbye, Hansen, Torben, Jørgensen, Niklas Rye, Jensen, J. B., Holst, Jens Juul, Madsbad, Sten & Torekov, Signe Sørensen, 2015, In: The Journal of clinical endocrinology and metabolism. 100, 8, p. 2909 –2917 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    No changes in serum tryptase after bariatric surgery

    Skaaby, T., drb459, drb459, Thomsen, S., Knudsen, A. L., Jørgensen, Niklas Rye & Linneberg, Allan René, 2015, In: Annals of Epidemiology. 25, 10, p. 800-1 2 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    The role of P2X receptors in bone biology

    Jørgensen, Niklas Rye, Syberg, S. & Ellegaard, M., 2015, In: Current Medicinal Chemistry. 22, 7, p. 902-14 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. 2014
  31. Published

    Muscle strength, power and cardiorespiratory fitness are associated with bone mineral density in men aged 31-60 years

    Schwarz, Peter, Jørgensen, Niklas Rye, Nielsen, B., Laursen, A. S., Linneberg, Allan René & Aadahl, Mette, Dec 2014, In: Scandinavian Journal of Public Health. 42, 8, p. 773-779 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    Bone Geometry, Volumetric Density, Microarchitecture, and Estimated Bone Strength Assessed by HR-pQCT in Klinefelter Syndrome

    Shanbhogue, V. V., Hansen, S., Jørgensen, Niklas Rye, Brixen, K. & Gravholt, C. H., Nov 2014, In: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. 29, 11, p. 2474–2482 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    Genetic variants in the P2RX7 gene are associated with risk of multiple myeloma

    Vangsted, A. J., Klausen, T. W., Gimsing, P., Abildgaard, N., Andersen, N. F., Gang, A. O., Holmström, M., Gregersen, H., Vogel, U., Schwarz, Peter & Jørgensen, Niklas Rye, Aug 2014, In: European Journal of Haematology. 93, 2, p. 172-174 3 p.

    Research output: Contribution to journalComment/debateResearch

  34. Published

    Status of drug development for the prevention and treatment of osteoporosis

    Schwarz, Peter, Jørgensen, Niklas Rye & Abrahamsen, B., Mar 2014, In: Expert Opinion on Drug Discovery. 9, 3, p. 245-253 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    Carriers in mesenchymal stem cell osteoblast mineralization-State-of-the-art

    Dahl, M., Jørgensen, Niklas Rye, Hørberg, M. & Pinholt, E. M., Jan 2014, In: Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery. 42, 1, p. 41-7 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    Non-infectious osteomyelitis of the mandible in a young woman: a case report

    Rasmussen, A. Q., Andersen, U. B., Jørgensen, Niklas Rye & Schwarz, Peter, 2014, In: Journal of Medical Case Reports. 8, p. 1-4 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    Osteoblastic response to pectin nanocoating on titanium surfaces

    Gurzawska, K. A., Svava, R., Yihua, Y., Haugshøj, K. B., Dirscherl, K., Levery, S. B., Chrestensen, I. B., Damager, I., Weiss Nielsen, M., Jørgensen, Bodil, Jørgensen, Niklas Rye & Gotfredsen, Klaus, 2014, In: Materials Science and Engineering C: Materials for Biological Applications. 43, p. 117-125 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    Plasma plasminogen activator inhibitor-1 predicts myocardial infarction in HIV-1-infected individuals

    Knudsen, A., Katzenstein, T. L., Benfield, Thomas, Jørgensen, Niklas Rye, Kronborg, Gitte, Gerstoft, Jan, Obel, Niels, Kjær, Andreas & Lebech, Anne-Mette, 2014, In: AIDS. 28, 8, p. 1171-1179 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Recreational football improves bone mineral density and bone turnover marker profile in elderly men

    Helge, Eva Wulff, Rostgaard Andersen, T., Schmidt, J. F., Jørgensen, Niklas Rye, Hornstrup, T., Krustrup, P. & Bangsbo, Jens, 2014, In: Scandinavian Journal of Medicine & Science in Sports. 24, Suppl. 1, p. 98-104 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    The P2X7 receptor: a key player in immune-mediated bone loss?

    Kvist, T. M., Schwarz, Peter & Jørgensen, Niklas Rye, 2014, In: Scientific World Journal. 2014, p. 1-11 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    The structurally effect of surface coated rhamnogalacturonan I on response of the osteoblast-like cell line SaOS-2

    Svava, R., Gurzawska, K., Yihau, Y., Haugshøj, K. B., Dirscherl, K., Levery, S. B., Jørgensen, Niklas Rye, Gotfredsen, Klaus, Damager, I., Ulvskov, Peter & Jørgensen, Bodil, 2014, In: Journal of Biomedical Materials Research. Part A. 102, 6, p. 1961-1971 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published
  43. 2013
  44. Published

    Adipose derived mesenchymal stem cells – Their osteogenicity and osteoblast in vitro mineralization on titanium granule carriers

    Dahl, M., Syberg, S., Jørgensen, Niklas Rye & Pinholt, E. M., 13 Nov 2013, In: Journal of cranio-maxillo-facial surgery : official publication of the European Association for Cranio-Maxillo-Facial Surgery. 41, 2013, p. 213 -220 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    Functional polymorphisms in the P2X7 receptor gene are associated with osteoporosis

    Husted, L. B., Harsløf, T., Stenkjær, L., Carstens, M., Jørgensen, Niklas Rye & Langdahl, B. L., Mar 2013, In: Osteoporosis international : a journal established as result of cooperation between the European Foundation for Osteoporosis and the National Osteoporosis Foundation of the USA. 24, 3, p. 949-59 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    Association of P2X7 receptor polymorphisms with bone mineral density and osteoporosis risk in a cohort of Dutch fracture patients

    Wesselius, A., Bours, M. J. L., Henriksen, Z., Syberg, S., Petersen, S., Schwarz, Peter, Jørgensen, Niklas Rye, van Helden, S. & Dagnelie, P. C., 2013, In: Osteoporosis International. 24, 4, p. 1235-1246 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    Association of P2Y(2) receptor SNPs with bone mineral density and osteoporosis risk in a cohort of Dutch fracture patients

    Wesselius, A., Bours, M. J. L., Henriksen, Z., Syberg, S., Petersen, S., Schwarz, Peter, Jørgensen, Niklas Rye, van Helden, S. & Dagnelie, P. C., 2013, In: Purinergic Signalling. 9, 1, p. 41-9 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    Characterization of pectin nanocoatings at polystyrene and titanium surfaces

    Gurzawska, K. A., Dirscherl, K., Yihua, Y., Chrestensen, I. B., Jørgensen, Bodil, Svava, R., Nielsen, M. W., Jørgensen, Niklas Rye & Gotfredsen, Klaus, 2013, In: Journal of Surface Engineered Materials and Advanced Technology. 3, p. 20-28 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    Gastrointestinal Events with Clopidogrel: A Nationwide Population-Based Cohort Study

    Grove, E. L., Würtz, M., Schwarz, Peter, Jørgensen, Niklas Rye & Vestergaard, P., 2013, In: Journal of General Internal Medicine. 28, 2, p. 216-22 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    Non-synonymous polymorphisms in the P2RX ( 4 ) are related to bone mineral density and osteoporosis risk in a cohort of Dutch fracture patients

    Wesselius, A., Bours, M. J., Jørgensen, Niklas Rye, Wiley, J., Gu, B., van Helden, S., van Rhijn, L. & Dagnelie, P. C., 2013, In: Purinergic Signalling. 9, 1, p. 123-30 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  51. 2012
  52. Published

    Nanocoating of titanium implant surfaces with organic molecules. Polysaccharides including glycosaminoglycans

    Gurzawska, K. A., Svava, R., Jørgensen, Niklas Rye & Gotfredsen, Klaus, 2012, In: Journal of Biomedical Nanotechnology. 8, 6, p. 1012-24 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  53. 2009
  54. Published

    Alpha-hemolysin from Escherichia coli uses endogenous amplification through P2X receptor activation to induce hemolysis

    Skals, M., Jørgensen, Niklas Rye, Leipziger, J. & Praetorius, H. A., 2009, In: Proceedings of the National Academy of Science of the United States of America. 106, 10, p. 4030-5 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  55. 2008
  56. Published

    Variation in the purinergic P2RX(7) receptor gene and schizophrenia

    Hansen, T., Jakobsen, K. D., Fenger, M., Nielsen, J., Krane, K., Fink-Jensen, Anders, Lublin, H., Ullum, H., Timm, S., Wang, August Gabriel, Jørgensen, Niklas Rye & Werge, Thomas, 2008, In: Schizophrenia Research. 104, 1-3, p. 146-52 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

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ID: 985846